Anti-infection

阻害剤の選択性比較

カタログ番号	製品カタログ	溶解度(25°C)
カタログ番号	製品カタログ	水	DMSO	アルコール
S1047	Vorinostat (SAHA)	<1 mg/mL	52 mg/mL	'3 mg/mL
S1009	Dactolisib (BEZ235)	<1 mg/mL	0.01 mg/mL	'<1 mg/mL
S1102	U0126-EtOH	<1 mg/mL	85 mg/mL	''<1 mg/mL
S5001	Tofacitinib (CP-690550) Citrate	<1 mg/mL	100 mg/mL	'<1 mg/mL
S6845	GRL0617	<1 mg/mL	65 mg/mL	''22 mg/mL
S6848	3'-Fluoro-3'-deoxythymidine (Alovudine)	20 mg/mL	49 mg/mL	40 mg/mL
S4307	Auranofin			' mg/mL
S8969	EIDD-2801	20 mg/mL	66 mg/mL	'22 mg/mL
S0436	Pleconaril	˂1 mg/mL	76 mg/mL	76 mg/mL
S0470	RSV604	˂1 mg/mL	78 mg/mL	9 mg/mL
S0285	Bay 41-4109 racemate	˂1 mg/mL	79 mg/mL	11 mg/mL
S5183	PD 169316	<1 mg/mL	14 mg/mL	<1 mg/mL
S6814	GS-441524	<1 mg/mL	58 mg/mL	<1 mg/mL
S0038	AB-423	˂1 mg/mL	77 mg/mL	77 mg/mL
S6689	Merimepodib	<1 mg/mL	90 mg/mL	<1 mg/mL
S6771	MAC-545496	˂1 mg/mL	84 mg/mL	''˂1 mg/mL
S8932	Remdesivir (GS-5734)	<1 mg/mL	100 mg/mL	'16 mg/mL
S6676	Ebselen	<1 mg/mL	55 mg/mL	'<1 mg/mL
S4303	9-Aminoacridine	<1 mg/mL	38 mg/mL	38 mg/mL
S6549	PBTZ169	<1 mg/mL	5 mg/mL	4 mg/mL
S8873	Letermovir（AIC246）	<1 mg/mL	100 mg/mL	100 mg/mL
S1230	Flavopiridol (Alvocidib)	<1 mg/mL	15 mg/mL	8 mg/mL
S2003	Maraviroc	<1 mg/mL	100 mg/mL	'100 mg/mL
S1209	Fluorouracil (5-Fluorouracil, 5-FU)	<1 mg/mL	26 mg/mL	'<1 mg/mL
S1537	DMXAA (Vadimezan)	<1 mg/mL	7 mg/mL	''<1 mg/mL
S7046	Brefeldin A	<1 mg/mL	4 mg/mL	'<1 mg/mL
S7015	Birinapant	<1 mg/mL	100 mg/mL	''55 mg/mL
S1400	Tenofovir Disoproxil Fumarate	<1 mg/mL	100 mg/mL	'44 mg/mL
S1704	Emtricitabine	49 mg/mL	49 mg/mL	'9 mg/mL
S2597	Oseltamivir Phosphate	<1 mg/mL	4 mg/mL	<1 mg/mL
S3021	Rimonabant	<1 mg/mL	25 mg/mL	'2 mg/mL
S8030	Plerixafor (AMD3100)	3 mg/mL	<1 mg/mL	'100 mg/mL
S1386	Nafamostat Mesylate	53 mg/mL	20 mg/mL	'''<1 mg/mL
S1627	Nitazoxanide	<1 mg/mL	62 mg/mL	<1 mg/mL
S1623	Acetylcysteine	33 mg/mL	33 mg/mL	'33 mg/mL
S8047	Dynasore	<1 mg/mL	64 mg/mL	'<1 mg/mL
S4157	Chloroquine Phosphate	100 mg/mL	<1 mg/mL	'''<1 mg/mL
S2527	Methacycline HCl	5 mg/mL	3 mg/mL	<1 mg/mL
S1677	Chloramphenicol	<1 mg/mL	65 mg/mL	65 mg/mL
S2716	Peramivir Trihydrate	<1 mg/mL	0.2 mg/mL	<1 mg/mL
S1606	Clotrimazole	<1 mg/mL	11 mg/mL	69 mg/mL
S1956	Miconazole Nitrate	<1 mg/mL	96 mg/mL	1 mg/mL
S2557	Terbinafine HCl	<1 mg/mL	66 mg/mL	66 mg/mL
S2457	Clindamycin HCl	92 mg/mL	92 mg/mL	<1 mg/mL
S1611	Cefoperazone	<1 mg/mL	100 mg/mL	<1 mg/mL
S3007	Zanamivir	25 mg/mL	2 mg/mL	<1 mg/mL
S2908	Hygromycin B	100 mg/mL	<1 mg/mL	<1 mg/mL
S1854	Bifonazole	<1 mg/mL	62 mg/mL	20 mg/mL
S1876	Valaciclovir HCl	72 mg/mL	14 mg/mL	<1 mg/mL
S1997	Liranaftate	<1 mg/mL	<1 mg/mL	<1 mg/mL
S4042	Nafcillin Sodium	91 mg/mL	91 mg/mL	20 mg/mL
S1791	Bacitracin Zinc	<1 mg/mL	100 mg/mL	<1 mg/mL
S2572	Streptomycin sulfate	89 mg/mL	<1 mg/mL	<1 mg/mL
S1685	Sulfanilamide	<1 mg/mL	34 mg/mL	17 mg/mL
S8279	Shikonin	<1 mg/mL	57 mg/mL	23 mg/mL
S8750	NGI-1(ML414)	<1 mg/mL	79 mg/mL	<1 mg/mL
S2830	Clindamycin	<1 mg/mL	85 mg/mL	85 mg/mL
S7311	Q-VD-OPh	<1 mg/mL	100 mg/mL	'100 mg/mL
S5268	Solithromycin	<1 mg/mL	100 mg/mL	25 mg/mL
S7975	Favipiravir (T-705)	5 mg/mL	31 mg/mL	'22 mg/mL
S7550	Erythromycin Cyclocarbonate	<1 mg/mL	100 mg/mL	100 mg/mL
S7784	Fumagillin	<1 mg/mL	92 mg/mL	32 mg/mL
S4861	Oxindole	-1 mg/mL	26 mg/mL	-1 mg/mL
S3077	Tazobactam	<1 mg/mL	60 mg/mL	<1 mg/mL
S4946	2,3-Dihydroxybenzoic acid	-1 mg/mL	30 mg/mL	-1 mg/mL
S4647	Cefmenoxime hydrochloride	<1 mg/mL	70 mg/mL	<1 mg/mL
S5499	Amantadine	-1 mg/mL	1 mg/mL	-1 mg/mL
S4602	Acetohydroxamic acid	15 mg/mL	15 mg/mL	15 mg/mL
S9303	Saikosaponin B2	-1 mg/mL	100 mg/mL	-1 mg/mL
S9018	Luteoloside	-1 mg/mL	89 mg/mL	-1 mg/mL
S7775	Emricasan	<1 mg/mL	100 mg/mL	'''100 mg/mL
S9063	Harringtonine	-1 mg/mL	100 mg/mL	-1 mg/mL
S4430	Hydroxychloroquine Sulfate	67 mg/mL	<1 mg/mL	'<1 mg/mL
S9064	Trilobatin	-1 mg/mL	87 mg/mL	-1 mg/mL
S5704	Myclobutanil	-1 mg/mL	58 mg/mL	-1 mg/mL
S4983	Sorbic acid	<1 mg/mL	22 mg/mL	22 mg/mL
S9070	Isoxanthohumol	-1 mg/mL	70 mg/mL	-1 mg/mL
S4198	Aminothiazole	20 mg/mL	20 mg/mL	20 mg/mL
S9072	Sweroside	-1 mg/mL	71 mg/mL	-1 mg/mL
S5927	Proguanil	<1 mg/mL	51 mg/mL	51 mg/mL
S3710	Fosfomycin calcium	<1 mg/mL	0.1 mg/mL	<1 mg/mL
S5166	Benzoyleneurea	-1 mg/mL	32 mg/mL	-1 mg/mL
S5025	Efinaconazole	<1 mg/mL	69 mg/mL	69 mg/mL
S3667	Imipenem	63 mg/mL	1 mg/mL	<1 mg/mL
S4104	Diminazene Aceturate	100 mg/mL	19 mg/mL	<1 mg/mL
S4105	Closantel Sodium	<1 mg/mL	100 mg/mL	100 mg/mL
S4106	Closantel	<1 mg/mL	100 mg/mL	<1 mg/mL
S3711	Carbasalate Calcium	91 mg/mL	11 mg/mL	<1 mg/mL
S3732	Avibactam sodium	57 mg/mL	57 mg/mL	<1 mg/mL
S4701	2-Deoxy-D-glucose	32 mg/mL	32 mg/mL	'1 mg/mL
S9341	3,4-Dimethoxycinnamic acid	-1 mg/mL	42 mg/mL	-1 mg/mL
S2348	Rotenone (Barbasco)	<1 mg/mL	55 mg/mL	2 mg/mL
S4515	Ademetionine disulfate tosylate	79 mg/mL	79 mg/mL	<1 mg/mL
S3028	Geneticin	100 mg/mL	<1 mg/mL	<1 mg/mL
S7417	Puromycin 2HCl	100 mg/mL	100 mg/mL	<1 mg/mL
S4780	7-Methoxy-4-methylcoumarin	-1 mg/mL	38 mg/mL	-1 mg/mL
S4783	Benzyl isothiocyanate	-1 mg/mL	29 mg/mL	-1 mg/mL
S7867	Oleuropein	100 mg/mL	100 mg/mL	100 mg/mL
S4549	Antimonyl (potassium tartrate trihydrate)	100 mg/mL	<1 mg/mL	<1 mg/mL
S4286	Anidulafungin (LY303366)	<1 mg/mL	100 mg/mL	<1 mg/mL
S7419	Blasticidin S HCl	91 mg/mL	<1 mg/mL	'<1 mg/mL
S7465	FTI 277 HCl	17 mg/mL	96 mg/mL	'14 mg/mL
S4854	Bedaquiline fumarate	<1 mg/mL	100 mg/mL	4 mg/mL
S1958	Sulbactam	47 mg/mL	47 mg/mL	47 mg/mL
S4564	Diethylcarbamazine (citrate)	78 mg/mL	78 mg/mL	30 mg/mL
S4389	Bephenium Hydroxynaphthoate	<1 mg/mL	88 mg/mL	<1 mg/mL
S1208	Doxorubicin (Adriamycin) HCl	20 mg/mL	100 mg/mL	<1 mg/mL
S4408	Procodazole	<1 mg/mL	38 mg/mL	<1 mg/mL
S0443	Desciclovir	25 mg/mL	42 mg/mL	'''3 mg/mL
S9466	Methenamine Hippurate	-1 mg/mL	14 mg/mL	-1 mg/mL
S4404	Pasiniazid	<1 mg/mL	58 mg/mL	15 mg/mL
S6729	Besifovir	60 mg/mL	60 mg/mL	2 mg/mL
S6582	Ozenoxacin	<1 mg/mL	5 mg/mL	<1 mg/mL
S8871	Omadacycline tosylate	100 mg/mL	100 mg/mL	100 mg/mL
S6562	KKL-35	<1 mg/mL	32 mg/mL	<1 mg/mL
S3013	Plerixafor 8HCl (AMD3100 8HCl)	100 mg/mL	<1 mg/mL	'<1 mg/mL
S1373	Daptomycin	100 mg/mL	100 mg/mL	<1 mg/mL
S1408	Linezolid	<1 mg/mL	67 mg/mL	8 mg/mL
S1097	BTZ043 Racemate	<1 mg/mL	22 mg/mL	<1 mg/mL
S1517	Natamycin	<1 mg/mL	7 mg/mL	<1 mg/mL
S1403	Tigecycline	100 mg/mL	100 mg/mL	<1 mg/mL
S1878	Ganciclovir	<1 mg/mL	27 mg/mL	<1 mg/mL
S2504	Ribavirin	49 mg/mL	49 mg/mL	<1 mg/mL
S1807	Aciclovir	<1 mg/mL	45 mg/mL	<1 mg/mL
S1374	Doripenem Hydrate	26 mg/mL	36 mg/mL	<1 mg/mL
S1381	Meropenem	8 mg/mL	76 mg/mL	<1 mg/mL
S1162	PA-824	<1 mg/mL	72 mg/mL	16 mg/mL
S1934	Nystatin (Fungicidin)	<1 mg/mL	19 mg/mL	<1 mg/mL
S1741	Rifabutin	<1 mg/mL	60 mg/mL	40 mg/mL
S1370	Biapenem	16 mg/mL	<1 mg/mL	<1 mg/mL
S1351	Ivermectin	<1 mg/mL	100 mg/mL	'28 mg/mL
S1371	Cefoselis Sulfate	5 mg/mL	3 mg/mL	<1 mg/mL
S2159	Tebipenem Pivoxil	<1 mg/mL	99 mg/mL	87 mg/mL
S1636	Amphotericin B	<1 mg/mL	22 mg/mL	<1 mg/mL
S1282	Artemisinin	<1 mg/mL	57 mg/mL	24 mg/mL
S1399	Teicoplanin	100 mg/mL	<1 mg/mL	<1 mg/mL
S2468	Fenbendazole	<1 mg/mL	4 mg/mL	<1 mg/mL
S1505	Aztreonam	11 mg/mL	87 mg/mL	<1 mg/mL
S1725	Terbinafine	<1 mg/mL	58 mg/mL	58 mg/mL
S2510	Spectinomycin 2HCl	81 mg/mL	81 mg/mL	<1 mg/mL
S1768	Cefditoren Pivoxil	<1 mg/mL	100 mg/mL	<1 mg/mL
S1450	Nanchangmycin	<1 mg/mL	100 mg/mL	100 mg/mL
S1839	Chloroxine	<1 mg/mL	43 mg/mL	<1 mg/mL
S2264	Artemether	<1 mg/mL	60 mg/mL	60 mg/mL
S1666	Flucytosine	5 mg/mL	8 mg/mL	<1 mg/mL
S1998	D-Cycloserine	20 mg/mL	<1 mg/mL	<1 mg/mL
S2479	Lincomycin HCl	89 mg/mL	89 mg/mL	<1 mg/mL
S1605	Cefdinir	<1 mg/mL	79 mg/mL	<1 mg/mL
S3073	Caspofungin Acetate	100 mg/mL	-1 mg/mL	-1 mg/mL
S2528	Ciclopirox	<1 mg/mL	42 mg/mL	42 mg/mL
S2152	Sitafloxacin Hydrate	<1 mg/mL	4 mg/mL	<1 mg/mL
S1502	Cephalexin	10 mg/mL	1 mg/mL	<1 mg/mL
S1835	Azithromycin	<1 mg/mL	100 mg/mL	'100 mg/mL
S1773	Oxytetracycline (Terramycin)	<1 mg/mL	92 mg/mL	10 mg/mL
S1637	Docosanol	<1 mg/mL	<1 mg/mL	4 mg/mL
S2535	Econazole nitrate	<1 mg/mL	89 mg/mL	5 mg/mL
S2568	Neomycin sulfate	143 mg/mL	<1 mg/mL	<1 mg/mL
S1777	Ethionamide	<1 mg/mL	33 mg/mL	17 mg/mL
S1635	Erythromycin	3 mg/mL	147 mg/mL	147 mg/mL
S2420	Aloperine	12 mg/mL	2 mg/mL	46 mg/mL
S4226	Minocycline HCl	1 mg/mL	<1 mg/mL	<1 mg/mL
S2486	Moroxydine HCl	42 mg/mL	42 mg/mL	<1 mg/mL
S1644	Nitrofural	<1 mg/mL	40 mg/mL	<1 mg/mL
S3079	Atovaquone	<1 mg/mL	5 mg/mL	'<1 mg/mL
S4050	Valganciclovir HCl	78 mg/mL	78 mg/mL	<1 mg/mL
S4052	Netilmicin Sulfate	288 mg/mL	<1 mg/mL	<1 mg/mL
S4082	Spiramycin	<1 mg/mL	100 mg/mL	100 mg/mL
S2565	Amoxicillin Sodium	78 mg/mL	78 mg/mL	<1 mg/mL
S2544	Cefprozil hydrate	<1 mg/mL	<1 mg/mL	<1 mg/mL
S2563	Oxacillin sodium monohydrate	88 mg/mL	<1 mg/mL	<1 mg/mL
S3129	Trimethoprim	<1 mg/mL	58 mg/mL	<1 mg/mL
S2028	Diclazuril	<1 mg/mL	16 mg/mL	<1 mg/mL
S3161	Sertaconazole nitrate	<1 mg/mL	100 mg/mL	<1 mg/mL
S1499	Cefaclor	<1 mg/mL	11 mg/mL	<1 mg/mL
S1915	Sulfamethoxazole	<1 mg/mL	51 mg/mL	23 mg/mL
S2120	Arbidol HCl	<1 mg/mL	103 mg/mL	22 mg/mL
S2467	Famciclovir	64 mg/mL	64 mg/mL	48 mg/mL
S2031	Fenticonazole Nitrate	<1 mg/mL	104 mg/mL	2 mg/mL
S2574	Tetracycline HCl	96 mg/mL	96 mg/mL	<1 mg/mL
S2575	Vancomycin HCl	100 mg/mL	<1 mg/mL	<1 mg/mL
S1851	Oxibendazole	<1 mg/mL	1 mg/mL	<1 mg/mL
S2501	Pyrantel Pamoate	<1 mg/mL	100 mg/mL	<1 mg/mL
S4030	Gentamicin Sulfate	100 mg/mL	<1 mg/mL	<1 mg/mL
S2514	Tobramycin	94 mg/mL	<1 mg/mL	<1 mg/mL
S1762	Pyrazinamide	12 mg/mL	25 mg/mL	2 mg/mL
S1676	Amorolfine HCl	9 mg/mL	28 mg/mL	71 mg/mL
S4075	Zinc Pyrithione	<1 mg/mL	30 mg/mL	<1 mg/mL
S2530	7-Aminocephalosporanic acid	<1 mg/mL	1 mg/mL	<1 mg/mL
S2536	Miconazole	<1 mg/mL	83 mg/mL	83 mg/mL
S2543	Ceftiofur HCl	<1 mg/mL	100 mg/mL	22 mg/mL
S1691	Praziquantel	<1 mg/mL	63 mg/mL	'63 mg/mL
S4237	Primaquine Diphosphate	91 mg/mL	91 mg/mL	<1 mg/mL
S1964	Rimantadine	33 mg/mL	33 mg/mL	33 mg/mL
S1883	Idoxuridine	<1 mg/mL	35 mg/mL	<1 mg/mL
S3162	Tylosin tartrate	200 mg/mL	300 mg/mL	300 mg/mL
S1916	Sulfisoxazole	<1 mg/mL	53 mg/mL	2 mg/mL
S1770	Sulfadiazine	<1 mg/mL	50 mg/mL	<1 mg/mL
S3195	Azlocillin sodium salt	97 mg/mL	97 mg/mL	3 mg/mL
S4004	Ethambutol 2HCl	56 mg/mL	56 mg/mL	<1 mg/mL
S2469	Fleroxacin	<1 mg/mL	<1 mg/mL	<1 mg/mL
S2551	Sulbactam sodium	51 mg/mL	3 mg/mL	<1 mg/mL
S3116	Sulfathiazole	<1 mg/mL	51 mg/mL	<1 mg/mL
S1910	Tioconazole	<1 mg/mL	78 mg/mL	78 mg/mL
S2506	Roxithromycin	<1 mg/mL	167 mg/mL	167 mg/mL
S2048	Clindamycin Phosphate	101 mg/mL	<1 mg/mL	<1 mg/mL
S3055	Besifloxacin HCl	1 mg/mL	<1 mg/mL	<1 mg/mL
S4120	Sulconazole Nitrate	<1 mg/mL	92 mg/mL	<1 mg/mL
S2511	Sulfadoxine	<1 mg/mL	62 mg/mL	<1 mg/mL
S3067	Chlorhexidine 2HCl	<1 mg/mL	100 mg/mL	<1 mg/mL
S3059	Enrofloxacin	<1 mg/mL	3 mg/mL	<1 mg/mL
S4141	Dinitolmide	<1 mg/mL	45 mg/mL	1 mg/mL
S1977	Sarafloxacin HCl	<1 mg/mL	4 mg/mL	<1 mg/mL
S4146	Bacitracin	100 mg/mL	-1 mg/mL	-1 mg/mL
S4147	Azithromycin Dihydrate	10 mg/mL	100 mg/mL	100 mg/mL
S4044	Toltrazuril	<1 mg/mL	85 mg/mL	<1 mg/mL
S4254	Apramycin Sulfate	100 mg/mL	<1 mg/mL	<1 mg/mL
S4056	Retapamulin	<1 mg/mL	104 mg/mL	104 mg/mL
S3015	Amoxicillin	<1 mg/mL	73 mg/mL	<1 mg/mL
S4184	Penciclovir	1 mg/mL	34 mg/mL	<1 mg/mL
S4191	Betamipron	<1 mg/mL	39 mg/mL	39 mg/mL
S1957	Sulfamethizole	<1 mg/mL	54 mg/mL	10 mg/mL
S2537	Secnidazole	37 mg/mL	37 mg/mL	37 mg/mL
S4195	Broxyquinoline	<1 mg/mL	17 mg/mL	<1 mg/mL
S4196	Ethacridine lactate monohydrate	5 mg/mL	72 mg/mL	<1 mg/mL
S4093	Bismuth Subcitrate Potassium	100 mg/mL	<1 mg/mL	<1 mg/mL
S4094	Tetramisole HCl	41 mg/mL	<1 mg/mL	<1 mg/mL
S2539	Lomefloxacin HCl	6 mg/mL	1 mg/mL	<1 mg/mL
S2612	Ribitol	30 mg/mL	30 mg/mL	<1 mg/mL
S3122	Amikacin hydrate	100 mg/mL	<1 mg/mL	<1 mg/mL
S3105	Nadifloxacin	<1 mg/mL	20 mg/mL	<1 mg/mL
S4234	Capreomycin Sulfate	100 mg/mL	<1 mg/mL	<1 mg/mL
S3133	Sulfamethazine	<1 mg/mL	56 mg/mL	<1 mg/mL
S1855	Pefloxacin Mesylate	67 mg/mL	14 mg/mL	<1 mg/mL
S3154	Butenafine HCl	<1 mg/mL	70 mg/mL	70 mg/mL
S3156	Naftifine HCl	<1 mg/mL	<1 mg/mL	8 mg/mL
S1833	Butoconazole nitrate	<1 mg/mL	95 mg/mL	<1 mg/mL
S3179	Carbenicillin disodium	84 mg/mL	5 mg/mL	<1 mg/mL
S3193	Ticarcillin sodium	86 mg/mL	86 mg/mL	<1 mg/mL
S1881	Protionamide	<1 mg/mL	36 mg/mL	7 mg/mL
S1830	Oxfendazole	<1 mg/mL	10 mg/mL	<1 mg/mL
S4726	Lauric Acid	20 mg/mL	40 mg/mL	40 mg/mL
S5227	Erythromycin thiocyanate	-1 mg/mL	100 mg/mL	-1 mg/mL
S3941	Pinocembrin	<1 mg/mL	51 mg/mL	51 mg/mL
S5352	Cefminox Sodium	100 mg/mL	100 mg/mL	<1 mg/mL
S6235	Sodium dehydroacetate	-1 mg/mL	38 mg/mL	-1 mg/mL
S3621	Pazufloxacin mesylate	82 mg/mL	82 mg/mL	7 mg/mL
S5560	Midecamycin	<1 mg/mL	100 mg/mL	100 mg/mL
S3999	α-santonin	-1 mg/mL	49 mg/mL	-1 mg/mL
S5406	Sultamicillin Tosylate	9 mg/mL	100 mg/mL	100 mg/mL
S5048	Fosfomycin Disodium	36 mg/mL	<1 mg/mL	-1 mg/mL
S9200	Pneumocandin B0	-1 mg/mL	100 mg/mL	-1 mg/mL
S5051	Pipemidic acid	60 mg/mL	<1 mg/mL	-1 mg/mL
S5328	Gamithromycin	<1 mg/mL	100 mg/mL	100 mg/mL
S4576	Sulfabenzamide	<1 mg/mL	55 mg/mL	<1 mg/mL
S5353	Cefpiramide sodium	100 mg/mL	100 mg/mL	<1 mg/mL
S4848	Dalbavancin	100 mg/mL	100 mg/mL	<1 mg/mL
S5081	Ceforanide	-1 mg/mL	6 mg/mL	-1 mg/mL
S5951	Cefoxitin	<1 mg/mL	85 mg/mL	85 mg/mL
S5035	6-Aminopenicillanic acid	<1 mg/mL	1 mg/mL	<1 mg/mL
S5356	Ceftiofur	-1 mg/mL	100 mg/mL	-1 mg/mL
S9564	p-Hydroxy-cinnamic Acid	<1 mg/mL	33 mg/mL	33 mg/mL
S5012	Octenidine Dihydrochloride	-1 mg/mL	60 mg/mL	-1 mg/mL
S5411	Sultamicillin	-1 mg/mL	100 mg/mL	-1 mg/mL
S2583	Thiamphenicol	<1 mg/mL	71 mg/mL	<1 mg/mL
S3741	Benznidazole	<1 mg/mL	52 mg/mL	5 mg/mL
S3623	Ceftibuten dihydrate	-1 mg/mL	90 mg/mL	-1 mg/mL
S6288	Chlorhexidine diacetate	-1 mg/mL	100 mg/mL	-1 mg/mL
S4850	Flucloxacillin sodium	95 mg/mL	95 mg/mL	5 mg/mL
S9224	Dehydroandrographolide Succinate	-1 mg/mL	100 mg/mL	-1 mg/mL
S5944	Butenafine	<1 mg/mL	63 mg/mL	63 mg/mL
S4846	Meropenem Trihydrate	87 mg/mL	87 mg/mL	4 mg/mL
S5533	Tobramycin sulfate	100 mg/mL	<1 mg/mL	-1 mg/mL
S9226	Steviolbioside	-1 mg/mL	100 mg/mL	-1 mg/mL
S4594	Cephalothin	83 mg/mL	10 mg/mL	<1 mg/mL
S4865	Cefetamet pivoxil hydrochloride	<1 mg/mL	100 mg/mL	100 mg/mL
S5359	Butoconazole	-1 mg/mL	82 mg/mL	-1 mg/mL
S5941	Besifloxacin	<1 mg/mL	<1 mg/mL	<1 mg/mL
S4866	Nicarbazin	<1 mg/mL	9 mg/mL	<1 mg/mL
S5366	Fipronil	-1 mg/mL	87 mg/mL	-1 mg/mL
S4420	Mefloquine HCl	<1 mg/mL	82 mg/mL	82 mg/mL
S3966	Nifuratel	<1 mg/mL	57 mg/mL	<1 mg/mL
S4880	Cefathiamidine	-1 mg/mL	94 mg/mL	-1 mg/mL
S5531	Doripenem	-1 mg/mL	60 mg/mL	-1 mg/mL
S3971	Fusidine	-1 mg/mL	100 mg/mL	-1 mg/mL
S1617	Sulfapyridine	<1 mg/mL	2 mg/mL	<1 mg/mL
S5332	Cefquinome sulfate	9 mg/mL	100 mg/mL	<1 mg/mL
S5278	Tedizolid (TR-700)	-1 mg/mL	10 mg/mL	-1 mg/mL
S4029	Colistin Sulfate	100 mg/mL	<1 mg/mL	<1 mg/mL
S4122	Tilmicosin	8 mg/mL	100 mg/mL	<1 mg/mL
S2052	Oxytetracycline Dihydrate	<1 mg/mL	5 mg/mL	<1 mg/mL
S5532	Erythromycin estolate	-1 mg/mL	100 mg/mL	-1 mg/mL
S5535	Moxifloxacin	-1 mg/mL	24 mg/mL	-1 mg/mL
S5684	Lapachol	-1 mg/mL	48 mg/mL	-1 mg/mL
S4876	Robenidine Hydrochoride	-1 mg/mL	74 mg/mL	-1 mg/mL
S4869	Sulfamethoxazole sodium	-1 mg/mL	55 mg/mL	-1 mg/mL
S5719	Ceftizoxime sodium	81 mg/mL	81 mg/mL	<1 mg/mL
S2058	Tolnaftate	<1 mg/mL	62 mg/mL	<1 mg/mL
S5054	Rifamycin sodium salt	-1 mg/mL	100 mg/mL	-1 mg/mL
S4584	Butylparaben	38 mg/mL	38 mg/mL	38 mg/mL
S5207	Cephalexin Monohydrate	<1 mg/mL	0.01 mg/mL	<1 mg/mL
S4585	Succinylsulfathiazole	<1 mg/mL	71 mg/mL	<1 mg/mL
S5491	Lomefloxacin	-1 mg/mL	7 mg/mL	-1 mg/mL
S4142	Clopidol	<1 mg/mL	1 mg/mL	<1 mg/mL
S4592	SBE-β-CD	100 mg/mL	<1 mg/mL	<1 mg/mL
S5331	Ceftezole sodium	92 mg/mL	92 mg/mL	<1 mg/mL
S4595	Cefazolin Sodium	95 mg/mL	95 mg/mL	<1 mg/mL
S5333	Sulbenicillin Sodium	91 mg/mL	91 mg/mL	<1 mg/mL
S5936	Cefazolin	<1 mg/mL	91 mg/mL	<1 mg/mL
S4145	Decoquinate	<1 mg/mL	0.01 mg/mL	<1 mg/mL
S4596	Cefixime	<1 mg/mL	90 mg/mL	1 mg/mL
S5700	Phthalylsulfathiazole	-1 mg/mL	80 mg/mL	-1 mg/mL
S4148	Ampicillin Trihydrate	2 mg/mL	81 mg/mL	<1 mg/mL
S4996	Tavaborole (AN-2690)	<1 mg/mL	30 mg/mL	30 mg/mL
S2259	Aloe-emodin	<1 mg/mL	3 mg/mL	<1 mg/mL
S4041	Olsalazine Sodium	41 mg/mL	4 mg/mL	<1 mg/mL
S4150	Orbifloxacin	<1 mg/mL	0.05 mg/mL	<1 mg/mL
S4620	Cefuroxime sodium	89 mg/mL	89 mg/mL	<1 mg/mL
S4875	Cephapirin Benzathine	-1 mg/mL	81 mg/mL	-1 mg/mL
S4885	Taurolidine	-1 mg/mL	56 mg/mL	-1 mg/mL
S4250	Sulfamethoxypyridazine	<1 mg/mL	56 mg/mL	<1 mg/mL
S9278	Saikosaponin C	-1 mg/mL	100 mg/mL	-1 mg/mL
S5397	Chlorhexidine	-1 mg/mL	100 mg/mL	-1 mg/mL
S4156	Chlortetracycline HCl	1 mg/mL	5 mg/mL	<1 mg/mL
S4158	Ceftriaxone Sodium Trihydrate	100 mg/mL	1 mg/mL	<1 mg/mL
S4160	Penicillin G Sodium	71 mg/mL	71 mg/mL	<1 mg/mL
S2271	Berberine chloride	<1 mg/mL	40 mg/mL	<1 mg/mL
S4942	4-Hydroxy-3,5-dimethoxybenzyl alcohol	-1 mg/mL	36 mg/mL	-1 mg/mL
S5492	Econazole	-1 mg/mL	76 mg/mL	-1 mg/mL
S4874	Cefazedone	-1 mg/mL	100 mg/mL	-1 mg/mL
S2282	Cinchonidine	<1 mg/mL	59 mg/mL	59 mg/mL
S5475	Novaluron	-1 mg/mL	99 mg/mL	-1 mg/mL
S9292	Dictamnine	-1 mg/mL	33 mg/mL	-1 mg/mL
S5296	Cephradine monohydrate	4 mg/mL	<1 mg/mL	-1 mg/mL
S5290	Ormetoprim	<1 mg/mL	0.01 mg/mL	<1 mg/mL
S5487	Cefoperazone sodium	-1 mg/mL	100 mg/mL	-1 mg/mL
S4610	Mebendazole	<1 mg/mL	6 mg/mL	<1 mg/mL
S4822	Silver Sulfadiazine	<1 mg/mL	0.1 mg/mL	<1 mg/mL
S5294	Cephalotin acid	-1 mg/mL	79 mg/mL	-1 mg/mL
S5736	Benzathine penicilline	-1 mg/mL	100 mg/mL	-1 mg/mL
S4167	Cyromazine	1 mg/mL	33 mg/mL	2 mg/mL
S4612	Dapson	<1 mg/mL	49 mg/mL	10 mg/mL
S1884	Sparfloxacin	<1 mg/mL	9 mg/mL	<1 mg/mL
S5722	Oxantel Pamoate	-1 mg/mL	100 mg/mL	-1 mg/mL
S1395	Polymyxin B sulphate	100 mg/mL	<1 mg/mL	<1 mg/mL
S2385	Hordenine	<1 mg/mL	33 mg/mL	33 mg/mL
S4634	Sodium sulfadiazine	54 mg/mL	9 mg/mL	<1 mg/mL
S4959	Skatole	-1 mg/mL	26 mg/mL	-1 mg/mL
S5601	Balofloxacin Dihydrate	<1 mg/mL	2 mg/mL	2 mg/mL
S4172	Cetylpyridinium Chloride	68 mg/mL	68 mg/mL	68 mg/mL
S4641	Tedizolid Phosphate	<1 mg/mL	22 mg/mL	<1 mg/mL
S3695	Cystamine dihydrochloride	45 mg/mL	14 mg/mL	2 mg/mL
S5291	sulfaisodimidine	-1 mg/mL	55 mg/mL	-1 mg/mL
S4175	Sulfaguanidine	<1 mg/mL	43 mg/mL	<1 mg/mL
S2395	Rheochrysidin	<1 mg/mL	1 mg/mL	<1 mg/mL
S3787	Picroside I	-1 mg/mL	98 mg/mL	-1 mg/mL
S3645	Kitasamycin	<1 mg/mL	100 mg/mL	100 mg/mL
S4178	Climbazole	<1 mg/mL	59 mg/mL	59 mg/mL
S3644	Sulfamonomethoxine	<1 mg/mL	56 mg/mL	4 mg/mL
S9016	Dipsacoside B	-1 mg/mL	100 mg/mL	-1 mg/mL
S3646	Thimerosal	80 mg/mL	80 mg/mL	20 mg/mL
S5298	Amoxicillin trihydrate	-1 mg/mL	30 mg/mL	-1 mg/mL
S5546	Sulfacetamide	-1 mg/mL	43 mg/mL	-1 mg/mL
S5908	Garenoxacin	<1 mg/mL	2 mg/mL	<1 mg/mL
S4179	Mezlocillin Sodium	100 mg/mL	100 mg/mL	<1 mg/mL
S4060	Erythromycin Ethylsuccinate	<1 mg/mL	172 mg/mL	172 mg/mL
S5515	Penicillin G Procaine	-1 mg/mL	100 mg/mL	-1 mg/mL
S3649	Ceftazidime	100 mg/mL	4 mg/mL	<1 mg/mL
S5289	Ceftezole	-1 mg/mL	88 mg/mL	-1 mg/mL
S4062	Ronidazole	<1 mg/mL	40 mg/mL	<1 mg/mL
S4183	Paromomycin Sulfate	100 mg/mL	<1 mg/mL	<1 mg/mL
S3655	Cefepime Dihydrochloride Monohydrate	1 mg/mL	100 mg/mL	<1 mg/mL
S5020	Tilorone dihydrochloride	96 mg/mL	43 mg/mL	96 mg/mL
S5637	Cefotiam Hexetil Hydrochloride	-1 mg/mL	100 mg/mL	-1 mg/mL
S4541	Triclosan	<1 mg/mL	57 mg/mL	57 mg/mL
S4971	Buparvaquone	<1 mg/mL	65 mg/mL	4 mg/mL
S5638	Cefozopran hydrochloride	-1 mg/mL	100 mg/mL	-1 mg/mL
S4187	Salicylanilide	<1 mg/mL	43 mg/mL	18 mg/mL
S5299	Tosufloxacin p-Toluenesulfonate Hydrate	-1 mg/mL	100 mg/mL	-1 mg/mL
S5644	Ceftriaxone Sodium	-1 mg/mL	100 mg/mL	-1 mg/mL
S4720	Cefotaxime	<1 mg/mL	91 mg/mL	<1 mg/mL
S4898	Sulfalozine sodium	-1 mg/mL	56 mg/mL	-1 mg/mL
S5295	Lincomycin Hydrochloride Monohydrate	-1 mg/mL	92 mg/mL	-1 mg/mL
S4068	Tinidazole	<1 mg/mL	49 mg/mL	<1 mg/mL
S3676	Carbendazim	<1 mg/mL	17 mg/mL	<1 mg/mL
S2315	Kanamycin sulfate	52 mg/mL	<1 mg/mL	<1 mg/mL
S4192	Chlorquinaldol	<1 mg/mL	46 mg/mL	6 mg/mL
S4258	Luliconazole	<1 mg/mL	71 mg/mL	5 mg/mL
S5420	Clindamycin alcoholate	-1 mg/mL	95 mg/mL	-1 mg/mL
S5816	pyrvinium	<1 mg/mL	22 mg/mL	<1 mg/mL
S4882	Resorantel	-1 mg/mL	61 mg/mL	-1 mg/mL
S5421	Fluoroquinolonic Acid	-1 mg/mL	25 mg/mL	-1 mg/mL
S5292	Diazolidinyl urea	-1 mg/mL	55 mg/mL	-1 mg/mL
S6423	Tildipirosin	-1 mg/mL	100 mg/mL	-1 mg/mL
S4750	Sulfacetamide sodium salt hydrate	50 mg/mL	50 mg/mL	2 mg/mL
S5017	Oxyclozanide	-1 mg/mL	80 mg/mL	-1 mg/mL
S9046	Berberine	1 mg/mL	45 mg/mL	5 mg/mL
S4870	Cefodizime Sodium	-1 mg/mL	100 mg/mL	-1 mg/mL
S9057	Sinigrin	-1 mg/mL	79 mg/mL	-1 mg/mL
S5887	Khellin	<1 mg/mL	26 mg/mL	7 mg/mL
S4081	Sulfacetamide Sodium	51 mg/mL	19 mg/mL	<1 mg/mL
S3636	Cefadroxil hydrate	1 mg/mL	7 mg/mL	<1 mg/mL
S3637	Cefpirome sulfate	100 mg/mL	100 mg/mL	<1 mg/mL
S4759	p-Coumaric Acid	<1 mg/mL	32 mg/mL	32 mg/mL
S3638	Cefamandole nafate	100 mg/mL	100 mg/mL	<1 mg/mL
S5440	Berberine Sulfate	-1 mg/mL	20 mg/mL	-1 mg/mL
S5948	Amodiaquine	<1 mg/mL	71 mg/mL	22 mg/mL
S5016	Isoprinosine	100 mg/mL	100 mg/mL	2 mg/mL
S2534	Isoconazole nitrate	<1 mg/mL	41 mg/mL	4 mg/mL
S4978	Azaerythromycin A\|Azaerythromycin	<1 mg/mL	50 mg/mL	100 mg/mL
S3713	Moxidectin	<1 mg/mL	100 mg/mL	100 mg/mL
S7411	Ascomycin (FK520)	<1 mg/mL	100 mg/mL	100 mg/mL
S5784	Vancomycin	<1 mg/mL	29 mg/mL	<1 mg/mL
S3705	Chlorobutanol	<1 mg/mL	35 mg/mL	35 mg/mL
S9387	Maackiain	-1 mg/mL	56 mg/mL	-1 mg/mL
S3707	Ethopabate	<1 mg/mL	47 mg/mL	47 mg/mL
S3708	Sulfachloropyridazine	<1 mg/mL	56 mg/mL	9 mg/mL
S4201	Florfenicol	<1 mg/mL	72 mg/mL	8 mg/mL
S4663	Fusidate Sodium	100 mg/mL	100 mg/mL	100 mg/mL
S3709	Furagin	<1 mg/mL	52 mg/mL	<1 mg/mL
S5041	Difloxacin hydrochloride	98 mg/mL	98 mg/mL	98 mg/mL
S4203	Furaltadone HCl	72 mg/mL	17 mg/mL	<1 mg/mL
S5657	Ertapenem sodium	100 mg/mL	100 mg/mL	<1 mg/mL
S9078	Epigoitrin	-1 mg/mL	4.89 mg/mL	-1 mg/mL
S4986	Latamoxef sodium	100 mg/mL	100 mg/mL	<1 mg/mL
S5033	Terconazole	<1 mg/mL	49 mg/mL	100 mg/mL
S9084	Rhoifolin	-1 mg/mL	100 mg/mL	-1 mg/mL
S6411	Nimorazole	-1 mg/mL	45 mg/mL	-1 mg/mL
S3058	Danofloxacin Mesylate	91 mg/mL	<1 mg/mL	<1 mg/mL
S4271	Isepamicin Sulphate	100 mg/mL	<1 mg/mL	<1 mg/mL
S3672	Cefonicid sodium	100 mg/mL	100 mg/mL	<1 mg/mL
S4213	Dirithromycin	<1 mg/mL	11 mg/mL	100 mg/mL
S4215	Ribostamycin Sulfate	100 mg/mL	<1 mg/mL	<1 mg/mL
S4216	Valnemulin HCl	100 mg/mL	100 mg/mL	100 mg/mL
S5055	Milbemycin Oxime	<1 mg/mL	100 mg/mL	100 mg/mL
S4671	Cefradine	10 mg/mL	<1 mg/mL	<1 mg/mL
S5070	Mupirocin calcium	6 mg/mL	100 mg/mL	100 mg/mL
S6067	2,4-dichlorobenzyl alcohol	-1 mg/mL	35 mg/mL	-1 mg/mL
S6068	Doxycycline monohydrate	-1 mg/mL	47 mg/mL	-1 mg/mL
S5724	Dichlorophene	-1 mg/mL	54 mg/mL	-1 mg/mL
S5829	Monomyristin	<1 mg/mL	60 mg/mL	60 mg/mL
S2334	Oleanolic Acid	<1 mg/mL	21 mg/mL	7 mg/mL
S9099	Orientin	-1 mg/mL	89 mg/mL	-1 mg/mL
S3801	Sodium Houttuyfonate	<1 mg/mL	2 mg/mL	<1 mg/mL
S5776	Proflavine	<1 mg/mL	23 mg/mL	2 mg/mL
S6444	Triclocarban	<1 mg/mL	63 mg/mL	5 mg/mL
S4222	Piperacillin Sodium	100 mg/mL	100 mg/mL	100 mg/mL
S4601	5-Chloro-8-hydroxy-7-iodoquinoline	<1 mg/mL	61 mg/mL	1 mg/mL
S3650	Penicillin V potassium salt	77 mg/mL	<1 mg/mL	<1 mg/mL
S6451	Salifungin	<1 mg/mL	65 mg/mL	5 mg/mL
S2613	Clorsulon	<1 mg/mL	76 mg/mL	7 mg/mL
S9328	5,6,7-Trimethoxyflavone	-1 mg/mL	10 mg/mL	-1 mg/mL
S4111	Dicloxacillin Sodium	100 mg/mL	100 mg/mL	22 mg/mL
S5065	Ganciclovir sodium	55 mg/mL	<1 mg/mL	-1 mg/mL
S5036	Nisin	6.7 mg/mL	7 mg/mL	<1 mg/mL
S6442	Chlorphenesin	10 mg/mL	41 mg/mL	41 mg/mL
S3722	Isavuconazole	<1 mg/mL	87 mg/mL	87 mg/mL
S5541	Dimetridazole	-1 mg/mL	28 mg/mL	-1 mg/mL
S9342	1,4-Naphthoquinone	-1 mg/mL	32 mg/mL	-1 mg/mL
S2564	Cloxacillin Sodium	55 mg/mL	55 mg/mL	25 mg/mL
S3121	Ornidazole	2 mg/mL	44 mg/mL	44 mg/mL
S3979	Zinc Undecylenate	-1 mg/mL	36 mg/mL	-1 mg/mL
S9112	Kaempferitrin	-1 mg/mL	100 mg/mL	-1 mg/mL
S5096	SulfadiMethoxine sodium	-1 mg/mL	66 mg/mL	-1 mg/mL
S9113	Ononin	-1 mg/mL	86 mg/mL	-1 mg/mL
S6464	Ftaxilide	<1 mg/mL	54 mg/mL	13 mg/mL
S5924	Olanexidine Hydrochloride semihydrate	<1 mg/mL	82 mg/mL	82 mg/mL
S6459	Nifurtimox	<1 mg/mL	57 mg/mL	<1 mg/mL
S4232	Nithiamide	<1 mg/mL	37 mg/mL	<1 mg/mL
S3618	Acetylspiramycin (ASPM)	<1 mg/mL	100 mg/mL	15 mg/mL
S9120	Scutellarein	-1 mg/mL	57 mg/mL	-1 mg/mL
S5410	Chloramphenicol sodium succinate	-1 mg/mL	89 mg/mL	-1 mg/mL
S6467	Fosfluconazole	<1 mg/mL	19 mg/mL	<1 mg/mL
S4517	Cefotaxime sodium	95 mg/mL	95 mg/mL	<1 mg/mL
S9122	Tectorigenin	-1 mg/mL	60 mg/mL	-1 mg/mL
S4518	Chloroxylenol	<1 mg/mL	31 mg/mL	31 mg/mL
S5209	Enoxacin Sesquihydrate	-1 mg/mL	4 mg/mL	-1 mg/mL
S3132	Sulfamerazine	<1 mg/mL	53 mg/mL	<1 mg/mL
S4236	Proflavine Hemisulfate	22 mg/mL	<1 mg/mL	<1 mg/mL
S5208	Ciprofloxacin hydrochloride hydrate	-1 mg/mL	8 mg/mL	-1 mg/mL
S5573	Tilmicosin phosphate	-1 mg/mL	100 mg/mL	-1 mg/mL
S3065	Amikacin disulfate	10 mg/mL	<1 mg/mL	<1 mg/mL
S4523	Dihydrostreptomycin sulfate	100 mg/mL	<1 mg/mL	<1 mg/mL
S3746	Lumefantrine	<1 mg/mL	13 mg/mL	<1 mg/mL
S5212	Imidazolidinyl Urea	-1 mg/mL	77 mg/mL	-1 mg/mL
S5473	Pivmecillinam hydrochloride	95 mg/mL	95 mg/mL	95 mg/mL
S9444	Tomatine	-1 mg/mL	100 mg/mL	-1 mg/mL
S4525	Ethylparaben	<1 mg/mL	33 mg/mL	33 mg/mL
S5210	Sulfamethazine Sodium Salt	-1 mg/mL	60 mg/mL	-1 mg/mL
S4528	Furazolidone	<1 mg/mL	45 mg/mL	<1 mg/mL
S4678	Povidone iodine	28 mg/mL	28 mg/mL	28 mg/mL
S5201	Acetylisovaleryltylosin Tartrate	-1 mg/mL	100 mg/mL	-1 mg/mL
S5206	Benzylpenicillin potassium	-1 mg/mL	74 mg/mL	-1 mg/mL
S5211	4-Aminosalicylic acid	-1 mg/mL	10 mg/mL	-1 mg/mL
S5094	Maduramycin Ammonium	-1 mg/mL	100 mg/mL	-1 mg/mL
S4833	Cefoxitin sodium	89 mg/mL	89 mg/mL	<1 mg/mL
S4536	Nitrofurantoin	<1 mg/mL	47 mg/mL	<1 mg/mL
S9135	Artemisic acid	-1 mg/mL	46 mg/mL	-1 mg/mL
S5093	Rafoxanide	-1 mg/mL	100 mg/mL	-1 mg/mL
S9136	Neochlorogenic acid	-1 mg/mL	70 mg/mL	-1 mg/mL
S3170	Ampicillin sodium	74 mg/mL	37 mg/mL	74 mg/mL
S5092	Febantel	-1 mg/mL	89 mg/mL	-1 mg/mL
S5350	Cefpodoxime proxetil	<1 mg/mL	100 mg/mL	100 mg/mL
S5557	Aklomide	-1 mg/mL	40 mg/mL	-1 mg/mL
S4540	Sisomicin sulfate	100 mg/mL	<1 mg/mL	<1 mg/mL
S4878	Neticonazole Hydrochloride	-1 mg/mL	67 mg/mL	-1 mg/mL
S5405	Propylparaben	<1 mg/mL	36 mg/mL	36 mg/mL
S4242	Cetrimonium Bromide (CTAB)	100 mg/mL	5 mg/mL	100 mg/mL
S5095	Olaquindox	<1 mg/mL	0.01 mg/mL	<1 mg/mL
S5214	Imidocarb dipropionate	-1 mg/mL	39 mg/mL	-1 mg/mL
S6461	Permethrin	<1 mg/mL	78 mg/mL	19 mg/mL
S3978	5-Phenyl-2,4-pentadienoic acid	-1 mg/mL	6 mg/mL	-1 mg/mL
S5159	Doxycycline	-1 mg/mL	88 mg/mL	-1 mg/mL
S4279	Demeclocycline HCl	26 mg/mL	100 mg/mL	<1 mg/mL
S5390	N-(Hytroxymethy)micotinamide	-1 mg/mL	30 mg/mL	-1 mg/mL
S5744	Spiramycin I	-1 mg/mL	100 mg/mL	-1 mg/mL
S4813	Cefuroxime axetil	-1 mg/mL	100 mg/mL	-1 mg/mL
S5373	Pseudolaric Acid B	<1 mg/mL	86 mg/mL	86 mg/mL
S5354	Cefteram pivoxil	<1 mg/mL	0.01 mg/mL	<1 mg/mL
S4843	Potassium acetate	-1 mg/mL	6 mg/mL	-1 mg/mL
S4550	Azelaic acid	37 mg/mL	37 mg/mL	37 mg/mL
S4844	Cefcapene Pivoxil Hydrochloride	-1 mg/mL	100 mg/mL	-1 mg/mL
S5355	Piperaquine phosphate	2 mg/mL	<1 mg/mL	-1 mg/mL
S5351	Cefmetazole sodium	98 mg/mL	98 mg/mL	1 mg/mL
S9560	Anisodamine Hydrobromide	-1 mg/mL	77 mg/mL	-1 mg/mL
S3910	4',7-Dimethoxyisoflavone	-1 mg/mL	4 mg/mL	-1 mg/mL
S5009	Brivudine	-1 mg/mL	66 mg/mL	-1 mg/mL
S4287	Micafungin Sodium	100 mg/mL	-1 mg/mL	-1 mg/mL
S5005	Cefotiam hydrochloride	-1 mg/mL	100 mg/mL	-1 mg/mL
S4553	Bronopol	39 mg/mL	39 mg/mL	39 mg/mL
S5859	Sancycline	<1 mg/mL	83 mg/mL	<1 mg/mL
S1962	Sulphadimethoxine	<1 mg/mL	62 mg/mL	<1 mg/mL
S5007	Delamanid	<1 mg/mL	100 mg/mL	2 mg/mL
S4555	Carsalam	<1 mg/mL	32 mg/mL	2 mg/mL
S4812	Ceftizoxime	<1 mg/mL	76 mg/mL	<1 mg/mL
S5863	Metronidazole Benzoate	<1 mg/mL	55 mg/mL	13 mg/mL
S4559	Cloxiquine	<1 mg/mL	35 mg/mL	35 mg/mL
S7896	Sodium Tauroursodeoxycholate (TUDC)	100 mg/mL	100 mg/mL	71 mg/mL
S4522	Dehydroacetic acid	<1 mg/mL	33 mg/mL	33 mg/mL
S5108	Tylosin	-1 mg/mL	100 mg/mL	-1 mg/mL
S4847	Faropenem Sodium	61 mg/mL	12 mg/mL	<1 mg/mL
S4565	Diiodohydroxyquinoline	<1 mg/mL	13 mg/mL	<1 mg/mL
S4999	Avermectin B1	-1 mg/mL	100 mg/mL	-1 mg/mL
S9185	Nitidine Chloride	-1 mg/mL	11 mg/mL	-1 mg/mL
S5456	Isobavachalcone	<1 mg/mL	64 mg/mL	64 mg/mL
S5247	Selamectin	-1 mg/mL	100 mg/mL	-1 mg/mL

Anti-infection製品

All (571) Anti-infection阻害剤(109) Anti-infection活性剤(1)

製品コード	製品説明	文献中Selleckの製品使用例	お客様のフィードバック
S1047	Vorinostat (SAHA) Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay. Vorinostat abrogates productive HPV-18 DNA amplification.	Nat Biotechnol, 2020, 10.1038/s41587-019-0388-4 Cancer Cell, 2020, 13;37(4):599-617 e7 Nucleic Acids Res, 2020, 10.1093/nar/gkaa088	Western blot analysis of histone H3 acetylation in the spleen of untreated and vorinostat-treated hNF-E2 tg mice (n = 4 of each genotype).
S1009	Dactolisib (BEZ235) Dactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3^TopBP1-ER cell. Dactolisib induces autophagy and suppresses HIV-1 replication. Phase 2.	Nat Commun, 2020, 14;11(1):1825 Genome Med, 2020, 18;12(1):17 Biomaterials, 2020, 246:120012	Three-dimensional responses of MCF7/IGF-1R cells to TAM (1 μM), E2 and IGF-1. Compared to parental MCF7 cells (a), MCF7/IGF-1R cells (b) in three-dimensional (3D) culture formed bigger acini in response to IGF-1 stimulation and displayed significant TAM resistance when treated with TAM (1 μM) + E2 + IGF-1, which was removable by kinase inhibitors BMS-536924, U0126 and BEZ235 (c). Cells (10,000/well) were seeded in 96-well plates. Acini were formed on 100% Matrigel and cultured for 14 days in starving medium containing 2% Matrigel and 5% charcoal/dextran-stripped fetal bovine serum with the treatments as indicated. Concentrations used: TAM (1 μM), E2 (1 nM) and IGF-1 (100 ng/mL). Confocal image original magnification, × 20. Red, rhodamine phalloidin (actin). Blue, Hoechst blue stain. Results are representative of two individual experiments.
S1102	U0126-EtOH U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. U0126 inhibits autophagy and mitophagy with antiviral activity.	Sci Adv, 2020, 1;6(18):eaaz7001 Autophagy, 2020, 16(6):1061-1076 EMBO Mol Med, 2020, 12(4):e11177	Cells were stimulated with TPA (10 nM) for 15 min in the presence of the indicated concentrations of U0126. Samples were collected and analyzed by Western blot to detect phosphorylated p42/p44 MAPK.
S5001	Tofacitinib (CP-690550) Citrate Tofacitinib citrate (CP-690550 citrate) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity.	J Clin Invest, 2020, 130(2):863-876 Cancer Discov, 2020, 10(4):608-625 J Neuroinflammation, 2020, 29;17(1):170	CP-690550 reduced the severity of ischemic damage. (A) CP-690550 (10 μM) suppressed IL-17 production by cdT cells and activated memory T cells. cdT cells and CD4+ CD44+ memory T cells isolated from C5BL6J mice through flow cytometry were stimulated for 24 h with plate-bound monoclonal antibodies to CD3 (2 ng/ml) and CD28 (1 ng/ml) in the presence or absence of IL-23 (25 ng/ml). IL-17A production and IL-17A expression level were measured by quantitative RT-PCR (a) and ELISA (b). (B) CBF reduction after brain ischemia. (C) Time-dependent changes in neurological score. *p < 0.05. (D) Infarct volume as visualized through TTC staining on day 3 in CP-690550 (CP)- and vehicle-treated mice.
S6845^新	GRL0617 GRL0617 is a potent, selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLPro)/deubiquitinase with IC50 of 0.6 μM and Ki of 0.49 μM. GRL0617 inhibits SARS-CoV viral replication in Vero E6 cells with EC50 of 15 microM and has no associated cytotoxicity.
S6848^新	3'-Fluoro-3'-deoxythymidine (Alovudine) 3'-Fluoro-3'-deoxythymidine (Alovudine) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer.
S4307^新	Auranofin Auranofin (SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.
S8969^新	EIDD-2801 EIDD-2801 is an orally bioavailable prodrug of the ribonucleoside analog β-d-N⁴-hydroxycytidine (NHC; EIDD-1931) with broad-spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and the causative agent of COVID-19.
S0436^新	Pleconaril Pleconaril is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication with IC50 of < 0.050 μM.
S0470^新	RSV604 RSV604, a novel benzodiazepine, is an inhibitor of respiratory syncytial virus (RSV) with EC50 of 0.86 μM. RSV604 has significant potential for the effective treatment of RSV disease. Phase 2.
S0285^新	Bay 41-4109 racemate BAY 41-4109 racemate is a mixture of R-isomer of BAY 41-4109 and S-isomer of BAY 41-4109. BAY 41-4109 an antiviral compound that inhibits human hepatitis B virus (HBV) with IC50 of 53 nM.
S5183^新	PD 169316 PD 169316 is a potent, selective and cell-permeable p38 MAP kinase inhibitor with IC50 of 89 nM. PD169316 abrogates signaling initiated by both TGFbeta and Activin A. PD169316 shows antiviral activity against Enterovirus71.
S6814^新	GS-441524 GS-441524, a molecular precursor to a pharmacologically active nucleoside triphosphate molecule, is a potent inhibitor of feline infectious peritonitis virus (FIPV) with EC50 of 0.78 μM.
S0038^新	AB-423 AB-423, a member of the sulfamoylbenzamide (SBA) class of hepatitis B virus (HBV) capsid inhibitors, shows potent inhibition of HBV replication with EC50 of 0.08 μM - 0.27 μM and EC90 of 0.33 μM - 1.32 μM in cells. Phase 1.
S6689^新	Merimepodib Merimepodib is a potent, specific, and reversible inosine monophosphate dehydrogenase(IMPDH) inhibitor with antiviral activity against hepatitis C virus (HCV) and a variety of DNA and RNA viruses in vitro.Merimepodib is an immunosuppressive agent.
S6771^新	MAC-545496 MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. MAC-545496 shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model.
S8932^新	Remdesivir (GS-5734) Remdesivir,a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.
S6676^新	Ebselen Ebselen is a small-molecule capsid inhibitor of HIV-1 Replication with IC50 of 46.1 nM in TR-FRET assay.
S4303^新	9-Aminoacridine 9-Aminoacridine is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.
S6549^新	PBTZ169 PBTZ169, an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1.	Cell Death Dis, 2019, 10(4):319
S8873^新	Letermovir（AIC246） Letermovir(AIC246, MK-8228) is a novel anti-CMV compound which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors.
S1230	Flavopiridol (Alvocidib) Flavopiridol (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4, CDK6, and CDK9 with IC50 values in the 20-100 nM range. It is more selective for CDK1, 2, 4, 6, 9 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol induces autophagy and ER stress. Flavopiridol blocks HIV-1 replication. Phase 1/2.	Nature, 2020, 580(7801):147-150 Mol Cell, 2020, 7;S1097-2765(20)30269-0 Nucleic Acids Res, 2020, 24;gkaa268	(C) In vivo treatment of Tg:Pomc-Pttg;Pomc-eGFP embryos with small-molecule CDK inhibitors (50 μM) or 0.2% DMSO as control from 18 to 40 hpf. One hundred to one hundred fifty embryos were treated with each compound. Representative images of live embryos are shown with gross morphology (Right) and pituitary Pomc-GFP-positive cells at higher magnification (Left) at 40 hpf. Embryos exposed to flavopiridol developed early developmental defect before pituitary POMC cell ontogeny occurs. (D) Relative expression of pituitary Pomc-eGFP fluorescence analyzed using Volocity 5.2 software (Improvision; mean ±SE of relative expression, n = 7). (E) R-roscovitine specifically suppresses expansion of pituitary POMC cells overexpressing zPttg from 18 to 48 hpf. Double transgenic Tg:Pomc-Pttg;Prl-RFP embryos were generated by breeding Tg:Pomc-Pttg fish with a previously generated PRL-RFP transgenic line, in which RFP was targeted to pituitary lactotrophs by a zebrafish Prolactin promoter (34). Representative fluorescent microscopy of pituitary POMC-eGFP (a and b) and PRL-RFP (c and d) expression in live Tg:Pomc-Pttg; Pomc-eGFP and Tg:Pomc-Pttg;Prl-RFP embryos treated with 0.2% DMSO (a and c) or 50 μM R-roscovitine (b and d). (F) Relative expression of pituitary POMC-eGFP or PRL-RFP fluorescence were analyzed (mean ±SE of relative expression; n = 10). Results represent one of three similar experiments;P < 0.02 and *P < 0.000005. (Scale bar, 50 μm.)
S2003	Maraviroc Maraviroc is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively. Maraviroc is used in the treatment of HIV infection.	Sci Adv, 2020, 22;6(21):eaaz8521 Mucosal Immunol, 2020, 28 Mol Cancer Ther, 2020, 13;molcanther11722019	CCR5 antagonists block FBS-induced breast cancer cell invasion. 3D reconstruction of FBS-induced invasion into collagen gels by Hs578T (A) or SUM-159 (C) breast cancer cells in presence of CCR5 antagonists (100 nmol/L). The corresponding quantifications (mean ±SEM, n = 3) and analysis (Bonferronit test) are displayed in B and D.
S1209	Fluorouracil (5-Fluorouracil, 5-FU) Fluorouracil (5-Fluorouracil, 5-FU) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.	Cancer Cell, 2020, 37(3):371-386 J Hematol Oncol, 2020, 1;13(1):40 Cancer Lett, 2020, 473:74-89	DNA-PKcs suppression mediated ROS production and GSH content in HepG2 cells exposed to CDDP and 5-Fu. a DNA-PKcs inhibition promoted ROS production in HepG2 cells treated with indicated concentrations of CDDP and 5-Fu. DCFH-DA fluorescent analysis was performed to assess the ROS level. Data presented were mean ?SD of three independent experiments.
S1537	DMXAA (Vadimezan) DMXAA (Vadimezan) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. DMXAA (Vadimezan) is also a STING agonist with potential antineoplastic activity. DMXAA (Vadimezan) potently induces IFN-β but relatively low TNF-α expression in vitro. DMXAA (Vadimezan) has antiviral activity. Phase 3.	Immunity, 2020, 7 pii: S1074-7613(20)30129-1 Cancer Discov, 2019, 9(6):722-737 ChemMedChem, 2018, 13(19):2057-2064	(B and C) sh-scrambled or sh-ck2a–transducted L929 cells (B) and Raw cells (C) were stimulated by DMXAA (100 μg/ml) for various times. Cytosolic and nuclear extracts were prepared as described in Materials and Methods. Five percent of the cytosolic proteins and 20% of the nuclear proteins were resolved by 10% SDS-PAGE. Subsequently, immunoblotting was conducted by indicated Abs. The amounts of Tubulin and Lamin B1 in cytosol versus nuclei detected by respective Abs were used as internal control for fractionation.
S7046	Brefeldin A Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy.	Cell Host Microbe, 2020, 11;27(3):476-485 e7 Ann Transl Med, 2020, 8(8):532 Nat Microbiol, 2019, 4(5):813-825	Cells were treated with brefeldin A or manumycin A, and the resulting supernatant was collected after 48 h for exosomal preparation (lanes 1 and 2), or exosomes obtained from C81 cells were trypsin-treated or freeze/thawed (F/T) and then trypsin-treated (lanes 3 and 4). Lanes 5 and 6, input exosome controls from C81 or CEM cells, respectively. Resulting exosomes were assayed for the presence of Tax by Western blotting.
S7015	Birinapant Birinapant is a SMAC mimetic antagonist, mostly to cIAP1 with K_d of <1 nM in a cell-free assay, less potent to XIAP. Birinapant helps to induce apoptosis in latent HIV-1-infected cells. Phase 2.	Cell Rep, 2020, 30(4):1260-1270 Cell Rep, 2020, 21;31(3):107547 Cell Death Differ, 2020, 26	Western blot analysis of XIAP and cIAP1 expression and PARP cleavage in H460, A549 and 34LU cells pre-treated with vorinostat or entinostat for 6h followed by the SMAC mimetic birinapant for 24h.
S1400	Tenofovir Disoproxil Fumarate Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination.	Antimicrob Agents Chemother, 2019, 64(1) Antimicrob Agents Chemother, 2018, 62(6) Antimicrob Agents Chemother, 2018, 62(9)	Human PBMCs containing indicated concentrations of Tenofovir disoproxil fumarate were inoculated with 5 ng mock-exposed or semen-exposed R5-HIV-luciferase, or 50 ng R5-HIV-luciferase as infectivity matched control. Infection rates were determined 3 days post inoculation.
S1704	Emtricitabine Emtricitabine (FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor. Intracellular half-life is 39 h.	JCI Insight, 2019, 4(12) Nat Med, 2018, 24(5):604-609 Antimicrob Agents Chemother, 2018, 62(9)
S2597	Oseltamivir Phosphate Oseltamivir Phosphate is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.	J Cell Mol Med, 2018, 22(3):1826-1839 Infect Immun, 2015, 10.1128/IAI.03118-14 Drug Metab Dispos, 2014, 42(9):1522-31	Nystatin, filipin III, and oseltamivir inhibit the labeling of trophozoites by CTXB and GM1 antibodies. (A) Trophozoites were treated with nystatin (27 μM), filipin III (7.6 μM), and oseltamivir (20 μM) for 30 min before labeling with Alexa Fluor-conjugated CTXB antibody (images a to d) and GM1 antibody (images a′ to d′). Myriocin (27 μM), a sphingolipid inhibitor, was used as a negative control (images e and e′). N, nucleus; PM, plasma membrane; F, flagella; VD, ventral disc. Bars, 5 μm. (B and C) Changes in intensity of control and inhibitor-treated trophozoites. For intensity measurements, cells were randomly selected from 10 to 15 fields from 3 to 5 separate experiments. Approximately 50 cells were considered for each condition and were analyzed using Zeiss Zen 2009 confocal software. One-way ANOVAs were performed to evaluate differences (means ± SDs) between the treatment and control groups. Mean intensities from 3 to 5 separate experiments are shown in panels B and C. Statistical significance was calculated using a one-way ANOVA test, followed by the Tukey (B) and Holm-Šídák (C) methods. , P < 0.05; , P < 0.01; **, P < 0.001; NS, not significant.
S3021	Rimonabant Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Rimonabant is also a dual inhibitor of acyl CoA:cholesterol acyltransferases(ACAT) 1 and 2 and inhibits mycobacterial MmpL3.	Microbiol Immunol, 2020, 10.1111/1348-0421.12777
S8030	Plerixafor (AMD3100) Plerixafor (AMD3100) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor inhibits human immunodeficiency virus (HIV) replication.	Cell Chem Biol, 2020, 10.1016/j.chembiol.2020.01.010 Mol Oncol, 2020, 14(4):779-794 J Biol Chem, 2020, 1 pii: jbc	BLI of NSG mice engrafted with BV173, treated with no therapy (control), plerixafor: 1 mg/kg IP daily, ESKM 100 ug twice weekly, and a combination of ESKM and plerixafor. (A) Logarithmic plot of BLI of leukemia growth measured weekly. Error bars are 5-95% confidence intervals. There was a small but not significant difference between ESKM and combination treated group. (B) End of therapy (day 34) BLI.
S1386	Nafamostat Mesylate Nafamostat mesilate is a synthetic serine protease inhibitor, used as an anticoagulant during hemodialysis. Nafamostat mesylate blocks activation of SARS-CoV-2 and is investigated as a new treatment option for COVID-19. Nafamostat Mesilate attenuates inflammation and apoptosis.	Br J Pharmacol, 2018, 175(17):3516-3533 Cancer Lett, 2016, 380(1):87-97 Med Oncol, 2016, 33(5):53	Immunofluorescence of NF-κB/p65 in HCT 116 and SW 1116 cells exposed to TNFα (25 ng/ml) with or without nafamostat mesilate(FLU) (100 μM). Scale bars: 20 μm.
S1627	Nitazoxanide Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM)	bioRxiv, 2020, 2020/9/20.4.7.30734 Nat Chem Biol, 2018, 14(1):94-101
S1623	Acetylcysteine Acetylcysteine(N-acetyl-l-cysteine) is a ROS(reactive oxygen species) inhibitor that antagonizes the activity of proteasome inhibitors. It is also a tumor necrosis factor production inhibitor. Acetylcysteine(N-acetyl-l-cysteine) suppresses TNF-induced NF-κB activation through inhibition of IκB kinases. Acetylcysteine(N-acetyl-l-cysteine) induces apoptosis via the mitochondria-dependent pathway. Acetylcysteine(N-acetyl-l-cysteine) inhibits ferroptosis and virus replication.Solutions of Acetylcysteine are best fresh-prepared.	Cell Death Differ, 2020, 10.1038/s41418-020-0496-1 J Hazard Mater, 2020, 5;391:122203 Oxid Med Cell Longev, 2020, 13;2020:3145182	(C) Double immunolabeling showed CK-labeled cells (green) co-expressed with 40, 6-diamidino-2-phenylindole (DAPI) (blue), scale bars are 50 μm.
S8047	Dynasore Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM in a cell-free assay, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase. Dynasore suppresses mTORC1 activity and induces autophagy. Dynasore inhibits the entry of several viruses, including herpes simplex virus (HSV).	Nat Cell Biol, 2020, 1 J Immunol, 2020, 204(5):1146-1157 Sci Rep, 2020, 26;10(1):8686	Immunocytochemistry demonstrates NR4A1 nuclear location at control (non-chymase treated) in HL-1 cells (a). Chymase (2.5 ug/ml) treatment for 2 h induces NR4A1 (red) cytoplasmic translocation in HL-1 cells as well as myosin (green) disruption (panel b). Active chymase enters HL-1 cells and is prevented by Dynasore (c and d). There marked entry into HL-1 cell nuclei and cytoplasm after treatment with chymase (5 ug/ml) for 2 h that is prevented by pre-treatment with Dynasore. Lack of co-staining with caveolin 3 (green) demonstrates that chymase is not transported via caveolae. Dynasore prevents transferrin uptake in HL-1 cells.
S4157	Chloroquine Phosphate Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs).	Autophagy, 2020, 10.1080/15548627.2020.1740529 Autophagy, 2020, 22:1-10 EMBO Rep, 2020, 6;21(5):e49232	NCI-H929 EV and miR-137 OE cells were treated with ATM activator Chloroquine Phosphate (CQ), specific ATM inhibitor KU-55933, and ATR inhibitor AZ20 for 12 hr. Immunoblotting showed the expression of p-ATM, p-Chk2, p-BRCA1, p-ATR and p-Chk1.
S2527	Methacycline HCl Methacycline HCl is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various infections.	Cancer Cell Int, 2020, 19;20:58 Sci Rep, 2018, 8(1):7653
S1677	Chloramphenicol Chloramphenicol is a bacteriostatic by inhibiting protein synthesis.
S2716	Peramivir Trihydrate Peramivir Trihydrate is a trihydrate of the anti-infection agent peramivir (RWJ-270201,BCX-1812) which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.	Emerg Microbes Infec, 2014, 3, e78 Emerg Microbes Infect, 2014, 3(11):e78	Dose-response curve of the SH5190, SH5190 R292K and the A(H1N1)pdm09 (2167) viruses in the presence of peramivir (C) using a chemiluminescent (NA-star) assay. The NA activity of the H7N9 or H1N1 viruses under increasing concentrations (0.03-1000 nM) of the NAIs was determined. Each data point represents the normalized mean ± SEM neuraminidase activity from three replicated wells. The experiments were repeated twice.
S1606	Clotrimazole Clotrimazole alters the permeability of the fungal cell wall by inhibiting the biosynthesis of ergosterol, used in the treatment of fungal infections.	J Cell Physiol, 2020, 10.1002 J Biol Chem, 2018, 293(1):333-344
S1956	Miconazole Nitrate Miconazole Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS, used to treat vaginal yeast infections.	Biomol Ther (Seoul), 2020, 25 Cell Death Dis, 2019, 10(6):413 FASEB J, 2019, 10.1096/fj.201802603RR
S2557	Terbinafine HCl Terbinafine HCl inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.	J Cell Mol Med, 2020, 25
S2457	Clindamycin HCl Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.	Proc Natl Acad Sci U S A, 2016, 113(50):14408-14413
S1611	Cefoperazone Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [³H]E₂17βG uptake with IC50 of 199 μM.
S3007	Zanamivir Zanamivir is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.	Emerg Microbes Infec, 2014, 3, e78 Emerg Microbes Infect, 2014, 3(11):e78	Dose-response curve of the SH5190, SH5190 R292K and the A(H1N1)pdm09 (2167) viruses in the presence of oseltamivir zanamivir (B) using a chemiluminescent (NA-star) assay. The NA activity of the H7N9 or H1N1 viruses under increasing concentrations (0.03-1000 nM) of the NAIs was determined. Each data point represents the normalized mean ± SEM neuraminidase activity from three replicated wells. The experiments were repeated twice.
S2908	Hygromycin B Hygromycin B, a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.	Cell Rep, 2020, 30(1):25-36 Mol Pharmacol, 2019, 96(1):13-25
S1854	Bifonazole Bifonazole is a substituted imidazole antifungal agent.	Nature, 2018, 560(7718):372-376	Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
S1876	Valaciclovir HCl Valaciclovir HCl, an aciclovir prodrug, inhibits activity of virus DNA polymerase, used to treat infections caused by herpes simplex virus (HSV) and varicella zoster virus, and for prophylaxis against cytomegalovirus (CMV).
S1997	Liranaftate Liranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities.
S4042	Nafcillin Sodium Nafcillin sodium reversibly inhibits β-lactamase with K_d of 33 mM.
S1791	Bacitracin Zinc Bacitracin is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.
S2572	Streptomycin sulfate Streptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor.
S1685	Sulfanilamide Sulfanilamide (Sulphanilamide) is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.
S8279	Shikonin Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay.	Phytomedicine, 2020, 68:153189 Acta Biochim Biophys Sin (Shanghai), 2020, 52(1):9-17 Int J Biol Sci, 2020, 16(1):147-161
S8750	NGI-1(ML414) NGI-1 is an aminobenzamide-sulfonamide compound that targets both oligosaccharyltransferase (OST) isoforms and therefore may exhibit antiviral activity against flaviviruses.
S2830	Clindamycin Clindamycin inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
S7311	Q-VD-OPh Q-VD-Oph is a potent pan-caspase inhibitor with IC50 ranged from 25 to 400 nM for caspases 1,3,8, and 9. Q-VD-OPh can inhibits HIV infection.	Nat Immunol, 2020, 21(5):546-554 Nat Commun, 2020, 24;11(1):1996 Cell Rep, 2020, 21;31(3):107547	UA and Q-VD-Oph attenuated TNF-α-induced unclear translocation of NF-κB (C) and P-STAT3(S727) (D) in BEAS-2B cells.
S5268	Solithromycin Solithromycin, belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
S4970	Cis-Geraniol\|Neryl alcohol Nerol is a monoterpene found in many essential oils such as lemongrass and hops.
S7975	Favipiravir (T-705) Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.	Viruses, 2020, 22;12(3) pii: E351 Mol Ther Methods Clin Dev, 2019, 14:47-55 PLoS Negl Trop Dis, 2019, 13(11):e0007904	(A) BoDV-1 infection was measured by IFA. BoDV-1 P40 was detected with a primary monoclonal antibody (red), nuclei were stained with DAPI (blue), merged image (scale bars: 50 μm). Favipiravir: T-705
S4941	Farnesol Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects.
S7550	Erythromycin Cyclocarbonate Erythromycin Cyclocarbonate, derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.
S4599	Benzyl benzoate Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
S7784	Fumagillin Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.
S4861	Oxindole Oxindole is an aromatic heterocyclic organic compound which causes sedation, muscle weakness, hypotension, and coma when dosed in excess.
S3077	Tazobactam Tazobactam is a β-lactamases Inhibitor with antibacterial activity. It also inhibits the class D oxacillinase OXA-2. It is used in combination with piperacillin and other β-lactam antibiotics to broaden their spectrum and enhance their effect.
S4946	2,3-Dihydroxybenzoic acid 2,3-Dihydroxybenzoic acid is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties.
S4647	Cefmenoxime hydrochloride Cefmenoxime, a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.
S5499	Amantadine Amantadine is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.
S4602	Acetohydroxamic acid Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.
S9303	Saikosaponin B2 Saikosaponin B2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.	Phytomedicine, 2019, 67:153163
S9018	Luteoloside Luteoloside is a member of the flavonoids family that exhibits several bioactivities including anti-microbial and anti-cancer activities. It is an inhibitor of 3C Protease of Enterovirus 71 with an IC50 value of 0.36 mM.
S5345	Nerolidol Nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.	Int Immunopharmacol, 2020, 80:106118
S7775	Emricasan Emricasan is a potent irreversible pan-caspase inhibitor. Emricasan is an inhibitor of Zika virus infection.	Nature, 2020, 580(7803):391-395 Nat Immunol, 2020, 21(5):546-554 Immunity, 2020, 22 pii: S1074-7613(20)30160-6
S9063	Harringtonine Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.
S4430	Hydroxychloroquine Sulfate Hydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.	Nat Commun, 2020, 24;11(1):1985 Geroscience, 2020, 10.1007/s11357-020-00166-4 J Cell Physiol, 2020, 10.1002/jcp.29433	C, SA-beta gal staining results of A549-LKB1 cells treated by trametinib (30 nmol/L), radiotherapy (2 Gy), and HCQ (50 μmol/L). Cells were treated by HCQ and/or trametinib 4 hours prior to radiotherapy. Drugs were washed out 24 hours after radiotherapy. Cells were incubated for additional 48 hours before staining. D, Clonogenic survival assay of A549-LKB1 cells treated with trametinib (30 nmol/L) and HCQ (50 μmol/L).
S9064	Trilobatin Trilobatin, a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect.
S5704	Myclobutanil Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S4983	Sorbic acid Sorbic acid is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
S9070	Isoxanthohumol Isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
S4198	Aminothiazole Aminothiazole can be used as a thyroid inhibitor and it has antibacterial activity.
S9072	Sweroside Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S5927	Proguanil Proguanil is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
S3710	Fosfomycin calcium Fosfomycin is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
S5166	Benzoyleneurea Benzoyleneurea scaffold is used in the synthesis of novel protein geranylgeranyltransferase-I inhibitors.
S5025	Efinaconazole Efinaconazole is an inhibitor of 14 alpha-demethylase which is involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes.
S3667	Imipenem Imipenem acts as an inhibitor of AmpC β-lactamase and is an antibiotic useful for the treatment of a number of bacterial infections.
S4104	Diminazene Aceturate Diminazene is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent.	Am J Physiol Lung Cell Mol Physiol, 2020, 10.1152/ajplung.00025.2020
S4105	Closantel Sodium Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
S4106	Closantel Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
S3711	Carbasalate Calcium Carbasalate calcium is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor.
S3732	Avibactam sodium Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor with IC50 values of 8, 80, and 38 nM for TEM-1, P99, and KPC-2 β-lactamases, respectively.	mBio, 2020, 14;11(2) pii: e00603-20
S4701	2-Deoxy-D-glucose 2-Deoxy-D-glucose, an analog of glucose, is a glycolytic inhibitor with antiviral activity. 2-Deoxy-D-glucose induces apoptosis and inhibits Herpes Simplex Virus type-1 (HSV-1) receptor expression.	Cancer Cell, 2020, 13;37(4):599-617 e7 PLoS Pathog, 2020, 9;16(6):e1008568 Metabolism, 2020, 13;107:154231	(B) 2-DG activates AMPK and suppresses H3K27me3, PRC2 of ovarian cancer cells in normoglycemic condition.
S9341	3,4-Dimethoxycinnamic acid 3,4-Dimethoxycinnamic acid is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S2348	Rotenone (Barbasco) Rotenone is a botanical insecticide that is an inhibitor of mitochondrial electron transport.	G3 (Bethesda), 2020, 4;10(5):1585-1597 Nat Commun, 2019, 10(1):3856 Mol Neurobiol, 2018, 55(5):4078-4089
S4515	Ademetionine disulfate tosylate Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.
S3028	Geneticin Geneticin (G418 Sulfate), an aminoglycoside antibiotic, is an elongation inhibitor of 80 S ribosomes that blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.	Mol Ther Oncolytics, 2020, 29;17:21-30 G3 (Bethesda), 2020, 4;10(5):1585-1597 Mol Cell, 2019, 75(6):1103-1116.e9
S7417	Puromycin 2HCl Puromycin 2HCl is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.	Autophagy, 2020, 15:1-13 Cell Rep, 2020, 30(2):497-509 Oncogene, 2020, 39(21):4212-4226
S4780	7-Methoxy-4-methylcoumarin 7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label.
S4783	Benzyl isothiocyanate Benzyl isothiocyanate (BITC) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities.	Biomolecules, 2019, 9(12)
S7867	Oleuropein Oleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2.
S4549	Antimonyl (potassium tartrate trihydrate) Antimony potassium tartrate trihydrate is a powerful emetic, also used in the treatment of schistosomiasis and leishmaniasis.
S4286	Anidulafungin (LY303366) Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.	Antimicrob Agents Chemother, 2020, 64(2) BMC Infect Dis, 2020, 19;20(1):287 Front Microbiol, 2020, 10:2936	Effect of Anidulafungin on hemolysis. Arithmetic means ± SEM (n = 8) of the percentage of hemolytic erythrocytes following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Anidulafungin (1.5-6 μg/ml). ***(p<0.001) indicates significant difference from the absence of Anidulafungin (ANOVA).
S7419	Blasticidin S HCl Blasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes, and acts as a DNA and protein synthesis inhibitor, used to select transfected cells carrying bsr or BSD resistance genes.	Cells, 2020, 9(1) Nat Chem Biol, 2019, 15(11):1110-1119 Cell, 2018, 174(6):1477-1491
S7465	FTI 277 HCl FTI 277 HCl is the methyl ester of FTI 277, which is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.	Nat Commun, 2019, 10(1):273 Cancer Lett, 2018, 442:202-212 Oncol Rep, 2018, 40(4):2171-2182	(A) HCT 116 cells were treated with Tram (0, 30, or 60 nM), and then treated with 10 μM FTI-277/4 μM GGTI-298 or vehicle control for 48 hr. CCK8 assays were performed to assess cell proliferation and growth. The data from a representative example of three independent experiments are presented as the mean±SD. (B) SW480 and MDA-MB-231 cells were treated with Tram (0, 80, 160 nM), and then treated with 10 μM FTI-277/4 μM GGTI-298 or vehicle control for 48 hr. CCK8 assays were performed to assess cell proliferation and growth. The data from a representative example of three independent experiments are presented as the mean±SD.
S4854	Bedaquiline fumarate Bedaquiline fumarate, an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.
S1958	Sulbactam Sulbactam is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.
S4564	Diethylcarbamazine (citrate) Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria and is highly specific for several parasites and does not contain any toxic metallic elements.
S4389^新	Bephenium Hydroxynaphthoate Bephenium is an activator of B-type Acetylcholine receptor (AChR). Bephenium selectively activates the Hco-L-AChR1 subtype made of Hco-UNC-29.1, Hco-UNC-38, Hco-UNC-63, Hco-ACR-8 subunits. Bephenium hydroxynaphthoate is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.
S1208	Doxorubicin (Adriamycin) HCl Doxorubicin (Adriamycin) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage, mitophagy and apoptosis in tumor cells. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.	Nat Commun, 2020, 24;11(1):1972 PLoS Biol, 2020, 23;18(3):e3000666 Cancer Res, 2020, 10.1158/0008-5472.CAN-19-2069	Cell viabilities with increasing concentrations of cisplatin (CP) and doxorubicin (DOXO) under normoxic and hypoxic condition for 48 hours were determined by MTT assay. IC50 values are presented as the means ?SDs (n=4) and * denotes p<0.05.
S4408^新	Procodazole Procodazole is used as a potentiator which is non-specific active immunoprotective against viral and bacterial infections.
S0443^新	Desciclovir Desciclovir (DCV) is a prodrug of the antiherpetic agent acyclovir (ACV) that converted into ACV by xanthine oxidase in humans.
S6761^新	Dalfopristin Dalfopristin is a semi-synthetic analogue of ostreogyrcin A, Quinupristin/dalfopristin is a new combination streptogramin product with a selective spectrum of antibacterial activity, mainly against gram-positive aerobic bacteria.
S9466^新	Methenamine Hippurate Methenamine Hippurate is the hippurate salt form of methenamine, a prodrug and inactive weak base that is hydrolyzed to formaldehyde in acid urine.Methenamine Hippurate is the component of Hiprex drug which has antibacterial activity.
S4393^新	Cephapirin Sodium Cephapirin Sodium is the sodium salt form of cephapirin, a semi-synthetic, first-generation cephalosporin antibiotic with bactericidal activity.Cephapirin Sodium is effective against gram-negative and gram-positive organisms.
S4404^新	Pasiniazid Pasiniazid is a composition of isoniazid and 4-aminosalicylic acid, used to treat tuberculosis patients.
S6729^新	Besifovir Besifovir is novel and potent acyclic nucleotide phosphonate used to treat hepatitis B virus (HBV) infection.
S4421^新	Josamycin Josamycin is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
S6582^新	Ozenoxacin Ozenoxacin is a quinolone antibiotic used for the treatment of impetigo.
S8871^新	Omadacycline tosylate Omadacycline is a first-in-class aminomethylcycline antibiotic, demonstrating antimicrobial activity in vitro against a range of Gram-positive and Gram-negative aerobes and some anaerobic bacteria.
S6562^新	KKL-35 KKL-35 inhibits the trans-translation tagging reaction with an IC50 of 0.9 µM. It has broad-spectrum antibiotic activity.
S3013	Plerixafor 8HCl (AMD3100 8HCl) Plerixafor 8HCl (AMD3100 8HCl) is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor can be used as an anti-HIV agent.	Mol Oncol, 2020, 14(4):779-794 Biol Reprod, 2019, 101(1):102-111 Gastroenterology, 2018, 155(3):880-891.e8	BLI of NSG mice engrafted with BV173, treated with no therapy (control), plerixafor: 1 mg/kg IP daily, ESKM 100 ug twice weekly, and a combination of ESKM and plerixafor. (A) Logarithmic plot of BLI of leukemia growth measured weekly. Error bars are 5-95% confidence intervals. There was a small but not significant difference between ESKM and combination treated group. (B) End of therapy (day 34) BLI.
S1373	Daptomycin Daptomycin is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.	Front Microbiol, 2020, 21;11:646 PLoS One, 2020, 15(2):e0228509 ACS Infect Dis, 2019, 5(4):539-549	Same experiment as in Figure 2 with fluorescent daptomycin shown as confocal images. A 7/3 DOPC/DOPG GUV (including 1% Rh-PE) was introduced at time zero into a solution containing 1 uM daptomycin with 0.5 uM BODIPY-daptomycin and 1 mM Ca2+. To show colocalization of lipid and peptide in aggregates, confocal images were taken: red for RH-PE and green for BODIPY-daptomycin. As the protrusion length decreased, aggregates appeared on the GUV surface containing both lipid and peptide. The scale bar is 10 um.
S1408	Linezolid Linezolid is a synthetic antibiotic used for the treatment of serious infections.	Front Microbiol, 2020, 11:265 J Mol Cell Biol, 2019, pii: mjz020 PLoS One, 2019, 14(10):e0222970
S1097	BTZ043 Racemate BTZ043 racemate is a decaprenylphosphoryl-β-_D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.	J Med Chem, 2020, 28;63(10):5367-5386 Biochem Pharmacol, 2019, 162:41-54 Blood Adv, 2019, 3(5):797-812
S1517	Natamycin Natamycin, a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil; with little to no flavour interference	Expert Opin Drug Deliv, 2020, 17(3):407-421
S1403	Tigecycline Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation.	Sci Rep, 2018, 8(1):11747 BMC Infect Dis, 2017, 17(1):197 J Clin Invest, 2016, 3;126(10):3739-3757	CHX blocked Pim-1 AUG isoform translocation from the cytosol to mitochondria and led to reduced pBADS112. Cox-2 was examined to assess the effect of tigecycline on mitochondrial translation. Cy-Cox-2: cytoplasmic Cox-2; Mt-Cox-2: mitochondrial Cox-2.
S1878	Ganciclovir Ganciclovir is an antiviral drug for feline herpesvirus type-1 with IC50 of 5.2 μM in a cell-free assay.	Mol Cancer Ther, 2020, 19(3):966-971 PLoS One, 2019, 14(6):e0218471 Cell Stem Cell, 2017, 20(3):407-414.e4	Effect of ganciclovir on viral DNA accumulation (A,B) and induction of TGF-β1 production after human cytomegalovirus infection in human trabecular meshwork cells (C). Cells were harvested at 5 day post-infection at a high multiplicity of infection (MOI 1) under the treatment with different concentrations of ganciclovir (GAN). Treatment with 10 μmol of ganciclovir significantly decreased the viral DNA accumulation (p < 0.001) (A,B). However, treatment with ganciclovir did not affect the TGF-β production using a TGF-β1 luciferase bioassay. Results are expressed as the mean +/− standard deviation of three different experiments.
S2504	Ribavirin Ribavirin, a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.	Toxicology, 2020, 15;435:152422 bioRxiv, 2020, 2020/9/20.4.7.30734 PLoS Negl Trop Dis, 2019, 13(7):e0007595	(E) Left panel, Western blot showed that 20 μM Ribavirin effectively inhibits elevated Sox2 expression in irradiated SW1990 cells. Right panel, qPCR analysis showed that Sox2 mRNA level in irradiated SW1990 cells at 48 hours was lower than that in non-irradiated SW1990 cells, *p < 0.05. (F) Left panel, Western blot showed 20 μM Ribavirin inhibits elevated Sox2 expression in irradiated BxPc-3 cells. Right panel, qPCR analysis showed that there is no significant fluctuation of Sox2 mRNA in irradiated BxPc-3 cells and Ribavirin did not influence sox2 mRNA level in irradiated BxPc-3 cells.
S1807	Aciclovir Aciclovir is a synthetic nucleoside analogue active against herpesviruses.	Sci Adv, 2019, 5(8):eaax0780 Nat Immunol, 2019, 20(12):1681-1691 Oncol Rep, 2017, 37(4):2109-2120	(A) HONE1 and (B) HK1-EBV cells were treated with TPA (40 ng/ml) and SB (3 mM) for EBV induction. After 3 h, uninduced and induced HONE1 and HK1-EBV cells were treated with the vehicle control (0.006% DMSO) or indicated concentrations of berberine for 48 h. Subsequently, the culture medium was harvested for quantitative-PCR analysis with EBNA1 primers. Each sample was normalized to the amount of the GAPDH gene; *p<0.05, compared with the control group.
S1374	Doripenem Hydrate Doripenem Hydrate is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections.	ACS Chem Biol, 2018, 13(8):2020-2026
S1381	Meropenem Meropenem is an ultra-broad spectrum injectable antibiotic.
S1162	PA-824 PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.
S1934	Nystatin (Fungicidin) Nystatin, which belongs to the polyene group of antimycotics, is frequently used as a topical agent in the treatment of oro-pharyngeal candidosis.	Biochim Biophys Acta Mol Cell Res, 2020, 1867(5):118676 Fish Shellfish Immunol, 2019, 84:138-147 International Journal of Peptide Research and Therapeutics, 2015, 10.1007/s10989-014-9440-x
S1741	Rifabutin Rifabutin is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.	Antibiotics (Basel), 2020, 9(2)
S1370	Biapenem Biapenem is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacterial strains.
S1351	Ivermectin Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug.	J Cell Mol Med, 2020, 24(9):5387-5401 Cureus, 2020, 12(1):e6714 Cell Death Dis, 2019, 10(2):118
S1371	Cefoselis Sulfate Cefoselis is a widely used beta-lactam antibiotic.
S2159	Tebipenem Pivoxil Tebipenem pivoxil is an oral carbapenem antibiotic, use to treat otolaryngologic and respiratory infections.
S1636	Amphotericin B Amphotericin B (AmB) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes.	J Antimicrob Chemother, 2019, 74(10):2950-2958 J Antimicrob Chemother, 2019, 74(10):2943-2949 Sci Rep, 2019, 9(1):9482
S1282	Artemisinin Artemisinin is a sesquiterpene endoperoxide which is a potent antimalarial agent.	Antiviral Res, 2020, 29:104810 Biomed Pharmacother, 2019, 117:109181
S1399	Teicoplanin Teicoplanin is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria.	Clin Exp Dent Res, 2016, 2(1):35-43
S2468	Fenbendazole Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.
S1505	Aztreonam Aztreonam is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.	Expert Opinion on Orphan Drugs, 2013, 1(7):549-556
S1725	Terbinafine Terbinafine is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.	J Cell Mol Med, 2020, 25 Eur J Pharm Sci, 2019, 136:104945 BMC Microbiol, 2018, 18(1):203
S2510	Spectinomycin 2HCl Spectinomycin 2HCl is a new parenteral antibiotic prepared from Streptomyces spectabilis.
S1768	Cefditoren Pivoxil Cefditoren Pivoxil is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria.
S1450	Nanchangmycin Nanchangmycin is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for mammals and plants.	Antimicrob Agents Chemother, 2020, 1;AAC.00289-20 J Virol, 2017, 91(23) Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 2015, 32(5):686-701
S1839	Chloroxine Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.	Front Microbiol, 2020, 10:2936
S2264	Artemether Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.	Cancer Cell Int, 2020, 19;20:58 PLoS Negl Trop Dis, 2015, 9(3):e0003593	Schistosomicidal effects of PZQ, ART(Artemether) and OXA on 14-day schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.
S1666	Flucytosine Flucytosine (5-Fluorocytosine, 5-FC) is an antifungal drug with IC50 of 0.93 μM in C. albicans.
S1998	D-Cycloserine D-cycloserine is an analog of the amino acid D-alanine, used as an antibiotic in the treatment of tuberculosis.
S2479	Lincomycin HCl Lincomycin hydrochloride(Lincocin) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.	Cancer Cell Int, 2020, 19;20:58 Proc Natl Acad Sci U S A, 2016, 113(50):14408-14413
S1605	Cefdinir Cefdinir is an oral cephalosporin antibiotic, used to treat bacterial infections in many different parts of the body.
S3073	Caspofungin Acetate Caspofungin acetate is an lipopeptide antifungal β-1,3-glucan synthase inhibitor.	Antimicrob Agents Chemother, 2020, 64(2) Biotechnol Adv, 2019, 37(6):107352 J Antimicrob Chemother, 2019, 74(10):2950-2958
S2528	Ciclopirox Ciclopirox is a broad-spectrum antifungal agent working as an iron chelator.
S2152	Sitafloxacin Hydrate Sitafloxacin Hydrate is a new-generation, broad-spectrum oral fluoroquinolone antibiotic.	Interact Cardiovasc Thorac Surg, 2018, 10.1093/icvts/ivy209 mSphere, 2018, 3(5)
S1502	Cephalexin Cephalexin is an antibiotic that can treat a number of bacterial infections.	Clin Cancer Res, 2018, 24(3):659-673 Theranostics, 2017, 7(7):2092-2107 Blood Cancer J, 2017, 10.1038/bcj.2017.61
S1835	Azithromycin Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.	Cancer Cell Int, 2020, 19;20:58 Clin Transl Med, 2020, 9(1):22 mBio, 2018, 9(5)
S1773	Oxytetracycline (Terramycin) Oxytetracycline is a broad-spectrum tetracycline antibiotic, used to treat infections with bacteria.	Sci Rep, 2018, 8(1):7653 Front Microbiol, 2016, 7: 1765	Effect of FDA approved drugs on EBOV transfected donor and recipient immune cells. (A) Varying concentrations of Cambinol and Esomepraole (1 nM, 1 μM, 10 μM), Oxytetracycline (1 nM, 10 nM, 10 μM), and DMSO (0.00001, 0.0001, 0.001%) treatments were administered to VP40-transfected 293T cells, followed by incubation for 3 days. Supernatant was centrifuged to remove cellular material and subsequently incubated for 72 h at 4°C with 20 μL of 30% slurry of NT80/82 beads. The NT pellet was washed twice with PBS and resuspended in SDS Laemmli buffer, followed by Western blot analysis for levels of exosomal markers CD63 and Alix. Actin levels were also analyzed. Mid-log phase EVTR2C cells (containing VP40) were treated with either low (0.1 μM), medium (1 μM), or high (10 μM) concentrations of Oxytetracycline and incubated for 5 days along with untreated 293T cells. Cell-free supernatants were harvested, filtered, and used to treat CEM (B), Jurkat (C), and U937 (D) cells. Cells were incubated for 5 days and assayed with CellTiter-Glo for viability. Statistical significance was determined using two-tailed student’s t-test with all groups compared to the untreated 293T cell control groups. RLU, Relative Luminescent Units. ∗p < 0.05, ∗∗∗p < 0.001.
S1637	Docosanol Docosanol is a saturated fatty alcoholused traditionally as an emollient, emulsifier, and thickener in cosmetics, nutritional supplement. (ED50=2.5 mg/mL for plaque inhibition, and ED50=1.7 mg/mL for inhibition of virus production)
S2535	Econazole nitrate Econazole Nitrate is a Ca2+ channel blocker, used as an antifungal medicine that fights infections caused by fungus.	Biomol Ther (Seoul), 2020, 25
S2568	Neomycin sulfate Neomycin sulfate is an aminoglycoside antibiotic, used to treat bacteria infections.	Mol Cell, 2020, 22 pii: S1097-2765(20)30231-8
S1777	Ethionamide Ethionamide is an antibiotic used in the treatment of tuberculosis.
S1635	Erythromycin Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).	J Med Chem, 2018, 61(9):4189-4202
S2420	Aloperine Aloperine is an isolated alkaloid in sophora plants such as Sophora alopecuroides L, and exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.	J Cancer Res Clin Oncol, 2020, 10.1007/s00432-020-03157-2 PeerJ, 2019, 7:e7652 Onco Targets Ther, 2018, 11:2735-2743
S4226	Minocycline HCl Minocycline HCl is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis.	J Neurosci, 2020, 40(2):297-310 Antimicrob Agents Chemother, 2020, 6 pii: AAC Neuropharmacology, 2020, 11:108132
S2486	Moroxydine HCl Moroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.	Cancer Cell Int, 2020, 19;20:58
S1644	Nitrofural Nitrofural is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg)
S3079	Atovaquone Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.	Sci Transl Med, 2015, 7(290):290ra89
S4050	Valganciclovir HCl Valganciclovir HCl is a prodrug for ganciclovir with antiviral activity used to treat cytomegalovirus infections.	Transl Res, 2016, 177:113-126
S4052	Netilmicin Sulfate Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics.	J Cancer Res Clin Oncol, 2019, 145(6):1495-1507
S4082	Spiramycin Spiramycin is a 16-membered ring macrolide (antibiotic).	Chemistry, 2020, 10.1002/chem.201905599
S2565	Amoxicillin Sodium Amoxicillin Sodium is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.	Toxicol Appl Pharmacol, 2015, 285(1):51-60
S2544	Cefprozil hydrate Cefprozil hydrate is a semi-synthetic broad-spectrum cephalosporin antibiotic, used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin.
S2563	Oxacillin sodium monohydrate Oxacillin sodium monohydrate is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.
S3129	Trimethoprim Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
S2028	Diclazuril Diclazuril is an anti-coccidial drug.
S3161	Sertaconazole nitrate Sertaconazole nitrate is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections.
S1499	Cefaclor Cefaclor is a cephalosporin antibiotic.
S1915	Sulfamethoxazole Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.
S2120	Arbidol HCl Arbidol HCl is a broad-spectrum antiviral compound that blocks viral fusion, used in treatment of influenza and other respiratory viral infections.
S2467	Famciclovir Famciclovir is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.	Cancer Cell Int, 2020, 19;20:58
S2031	Fenticonazole Nitrate Fenticonazole Nitrate is an azole antifungal agent.
S2574	Tetracycline HCl Tetracycline HCl is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.	PLoS Pathog, 2020, 16;16(3):e1008341 Sci Rep, 2018, 8(1):7653
S2575	Vancomycin HCl Vancomycin HCl is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent.
S1851	Oxibendazole Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.	Oncol Lett, 2018, 15(2):2218-2226
S2501	Pyrantel Pamoate Pyrantel Pamoate is a depolarizing neuromuscular blocking agent.
S4030	Gentamicin Sulfate Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.
S2514	Tobramycin Tobramycin is an aminoglycoside antibiotic with an IC50 of 9.7 μM.
S1762	Pyrazinamide Pyrazinamide is an agent used to treat tuberculosis.
S1676	Amorolfine HCl Amorolfine HCl is an antifungal reagent.	Cell Chem Biol, 2019, 26(4):593-599 Nature, 2018, 560(7718):372-376	b, GC–MS-based quantification of three metabolite levels in human glioma cells (GBM528) treated for 24 h with the indicated small molecules at the following concentrations: tamoxifen, 100 nM; clemastine, 2 μM; ifenprodil, 2 μM; ketoconazole, 2.5 μM; amorolfine, 100 nM. Left, lanosterol; centre, zymostenol; right, 14-dehydrozymostenol. n = 2 wells per condition.
S4075	Zinc Pyrithione Zinc pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.	Biol Reprod, 2019, 100(2):468-478 Cell Syst, 2017, 4(6-:600-610
S2530	7-Aminocephalosporanic acid 7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.
S2536	Miconazole Miconazole (Monistat) is an imidazole antifungal agent.	Biomol Ther (Seoul), 2020, 25
S2543	Ceftiofur HCl Ceftiofur HCl is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection.
S1691	Praziquantel Praziquantel is an anthelmintic effective against flatworms.

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Anti-infection

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Anti-infection製品