Anti-infection

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
水 DMSO アルコール
S1047 Vorinostat (SAHA) <1 mg/mL 52 mg/mL ''3 mg/mL
S1009 Dactolisib (BEZ235) <1 mg/mL 0.01 mg/mL <1 mg/mL
S1102 U0126-EtOH <1 mg/mL 85 mg/mL <1 mg/mL
S5001 Tofacitinib (CP-690550) Citrate <1 mg/mL 100 mg/mL '<1 mg/mL
S5979 2',3'-Dideoxyadenosine 47 mg/mL 47 mg/mL ''<1 mg/mL
S5967 Berberine chloride hydrate 39 mg/mL 78 mg/mL '<1 mg/mL
S4974 Oxacillin sodium 85 mg/mL 85 mg/mL ''8 mg/mL
S5199 Oxytetracycline hydrochloride 99 mg/mL 99 mg/mL ''<1 mg/mL
S4490 Tetracycline <1 mg/mL 89 mg/mL '''22 mg/mL
S5186 Cefpiramide <1 mg/mL 100 mg/mL ''<1 mg/mL
S4979 Procaine penicillin G 10 mg/mL 100 mg/mL '20 mg/mL
S5008 Ciprofloxacin hydrochloride 74 mg/mL 7 mg/mL '<1 mg/mL
S5495 Ceftiofur sodium 100 mg/mL 100 mg/mL '<1 mg/mL
S5959 Tenofovir Disoproxil <1 mg/mL 100 mg/mL '100 mg/mL
S4879 Tenofovir hydrate 10 mg/mL <1 mg/mL ''<1 mg/mL
S4945 Ethacridine lactate 69 mg/mL 69 mg/mL ''20 mg/mL
S4488 Delafloxacin Meglumine 100 mg/mL 100 mg/mL '''<1 mg/mL
S6584 Amdinocillin 65 mg/mL 65 mg/mL ''65 mg/mL
S4446 Dimercaprol ' mg/mL
S4425 Rifamycin S <1 mg/mL 100 mg/mL '100 mg/mL
S4436 Pleuromutilin <1 mg/mL 76 mg/mL '76 mg/mL
S4491 Cetylpyridinium chloride monohydrate 72 mg/mL 72 mg/mL '72 mg/mL
S9731 PF-00835231 <1 mg/mL 95 mg/mL '''95 mg/mL
S3500 Pentosan Polysulfate Sodium 100 mg/mL <1 mg/mL '<1 mg/mL
S3499 Monocaprylin <1 mg/mL 44 mg/mL ''44 mg/mL
S3496 Lefamulin acetate (Xenleta) 100 mg/mL 100 mg/mL '''''100 mg/mL
S0861 Laninamivir Octanoate <1 mg/mL 95 mg/mL '''''5 mg/mL
S3356 Phosphonoacetic acid 28 mg/mL 28 mg/mL '''28 mg/mL
S3380 Tecovirimat <1 mg/mL 75 mg/mL '''''75 mg/mL
S4417 Ceftaroline Fosamil <1 mg/mL 73 mg/mL ''''<1 mg/mL
S3226 Dehydroabietic acid -1 mg/mL 100 mg/mL -1 mg/mL
S3295 Taxifolin 7-rhamnoside -1 mg/mL 100 mg/mL -1 mg/mL
S3308 Caftaric acid -1 mg/mL 100 mg/mL -1 mg/mL
S3220 Trigonelline -1 mg/mL 50 mg/mL -1 mg/mL
S3261 Myrislignan -1 mg/mL 100 mg/mL -1 mg/mL
S9669 U18666A 40 mg/mL 30 mg/mL ''''85 mg/mL
S6867 Glyceryl monocaprate (Monocaprin) <1 mg/mL 49 mg/mL '49 mg/mL
S2764 DTNB <1 mg/mL 79 mg/mL 79 mg/mL
S6801 AKOS B018304 <1 mg/mL 53 mg/mL 2 mg/mL
S6802 Etosalamide 6 mg/mL 42 mg/mL '42 mg/mL
S8512 Cenicriviroc (TAK-652) <1 mg/mL 100 mg/mL ''100 mg/mL
S6845 GRL0617 <1 mg/mL 65 mg/mL 22 mg/mL
S6848 3'-Fluoro-3'-deoxythymidine (Alovudine) 20 mg/mL 49 mg/mL '40 mg/mL
S0833 EIDD-1931 15 mg/mL -1 mg/mL '3 mg/mL
S8969 Molnupiravir (EIDD-2801) 20 mg/mL 66 mg/mL '22 mg/mL
S1230 Flavopiridol (L86-8275) <1 mg/mL 15 mg/mL ''8 mg/mL
S2003 Maraviroc (UK-427857) <1 mg/mL 100 mg/mL '100 mg/mL
S2679 Flavopiridol (L86-8275) HCl <1 mg/mL 88 mg/mL '<1 mg/mL
S2728 AG-1478 (Tyrphostin AG-1478) <1 mg/mL 25 mg/mL 13 mg/mL
S1209 Fluorouracil (5-Fluorouracil, 5-FU) <1 mg/mL 26 mg/mL '<1 mg/mL
S1537 Vadimezan (ASA404) <1 mg/mL 7 mg/mL '''<1 mg/mL
S1117 Triciribine (NSC 154020) <1 mg/mL 64 mg/mL ''<1 mg/mL
S1228 Idarubicin HCl 5 mg/mL 100 mg/mL <1 mg/mL
S7046 Brefeldin A <1 mg/mL 4 mg/mL <1 mg/mL
S1189 Aprepitant (MK-0869) <1 mg/mL 107 mg/mL '15 mg/mL
S2713 Geldanamycin (NSC 122750) <1 mg/mL 36 mg/mL '<1 mg/mL
S1401 Tenofovir 2 mg/mL 4 mg/mL <1 mg/mL
S7015 Birinapant (TL32711) <1 mg/mL 100 mg/mL '55 mg/mL
S1400 Tenofovir (GS 1278) Disoproxil Fumarate <1 mg/mL 100 mg/mL '''44 mg/mL
S1704 Emtricitabine (BW 1592) 49 mg/mL 49 mg/mL ''9 mg/mL
S2597 Oseltamivir Phosphate <1 mg/mL 4 mg/mL '<1 mg/mL
S3021 Rimonabant (SR141716) <1 mg/mL 25 mg/mL '''2 mg/mL
S8030 Plerixafor (AMD3100) 3 mg/mL <1 mg/mL '100 mg/mL
S1896 Hydroxyurea (NSC-32065) 15 mg/mL 15 mg/mL ''<1 mg/mL
S1386 Nafamostat mesilate (FUT-175) 53 mg/mL 20 mg/mL '<1 mg/mL
S1627 Nitazoxanide (NSC 697855) <1 mg/mL 62 mg/mL '''<1 mg/mL
S1623 Acetylcysteine (N-acetylcysteine) 33 mg/mL 33 mg/mL '33 mg/mL
S1384 Mizoribine 51 mg/mL 1 mg/mL <1 mg/mL
S8047 Dynasore <1 mg/mL 64 mg/mL <1 mg/mL
S1848 Curcumin <1 mg/mL 73 mg/mL '<1 mg/mL
S4157 Chloroquine diphosphate 100 mg/mL <1 mg/mL <1 mg/mL
S2310 Honokiol (NSC 293100) <1 mg/mL 53 mg/mL '''<1 mg/mL
S2239 Tubacin <1 mg/mL 100 mg/mL <1 mg/mL
S1351 Ivermectin (MK-933) <1 mg/mL 100 mg/mL '28 mg/mL
S2527 Methacycline HCl 5 mg/mL 3 mg/mL <1 mg/mL
S1677 Chloramphenicol <1 mg/mL 65 mg/mL 65 mg/mL
S2716 Peramivir Trihydrate <1 mg/mL 0.2 mg/mL '<1 mg/mL
S2457 Clindamycin HCl 92 mg/mL 92 mg/mL <1 mg/mL
S1611 Cefoperazone <1 mg/mL 100 mg/mL <1 mg/mL
S3007 Zanamivir 25 mg/mL 2 mg/mL '<1 mg/mL
S2908 Hygromycin B 100 mg/mL <1 mg/mL '<1 mg/mL
S1997 Liranaftate <1 mg/mL <1 mg/mL '<1 mg/mL
S1791 Bacitracin Zinc <1 mg/mL 100 mg/mL <1 mg/mL
S2572 Streptomycin sulfate 89 mg/mL <1 mg/mL <1 mg/mL
S1618 Sulfameter <1 mg/mL 56 mg/mL <1 mg/mL
S1685 Sulfanilamide <1 mg/mL 34 mg/mL 17 mg/mL
S8279 Shikonin (C.I. 75535) <1 mg/mL 57 mg/mL 23 mg/mL
S8750 NGI-1 (ML414) <1 mg/mL 79 mg/mL <1 mg/mL
S5144 Neferine -1 mg/mL 100 mg/mL -1 mg/mL
S0515 PLpro inhibitor  <1 mg/mL 69 mg/mL '''35 mg/mL
S2830 Clindamycin <1 mg/mL 85 mg/mL 85 mg/mL
S7311 Q-VD-Oph <1 mg/mL 100 mg/mL '100 mg/mL
S0285 Bay 41-4109 racemate ˂1 mg/mL 79 mg/mL '11 mg/mL
S0038 AB-423 ˂1 mg/mL 77 mg/mL 77 mg/mL
S0289 KIN1148 <1 mg/mL 84 mg/mL '''''14 mg/mL
S5268 Solithromycin <1 mg/mL 100 mg/mL '25 mg/mL
S7975 Favipiravir (T-705) 5 mg/mL 31 mg/mL 22 mg/mL
S7550 Erythromycin Cyclocarbonate <1 mg/mL 100 mg/mL 100 mg/mL
S7784 Fumagillin <1 mg/mL 92 mg/mL 32 mg/mL
S0076 ABX464 <1 mg/mL 68 mg/mL 68 mg/mL
S1553 Delafloxacin (ABT-492) <1 mg/mL 88 mg/mL '<1 mg/mL
S4861 Oxindole -1 mg/mL 26 mg/mL '-1 mg/mL
S4946 2,3-Dihydroxybenzoic acid -1 mg/mL 30 mg/mL -1 mg/mL
S6676 Ebselen <1 mg/mL 55 mg/mL '<1 mg/mL
S4647 Cefmenoxime hydrochloride <1 mg/mL 70 mg/mL <1 mg/mL
S5499 Amantadine -1 mg/mL 1 mg/mL '-1 mg/mL
S4602 Acetohydroxamic acid 15 mg/mL 15 mg/mL 15 mg/mL
S8133 Resiquimod (R-848) <1 mg/mL 63 mg/mL ''''21 mg/mL
S8588 ACSS2 inhibitor <1 mg/mL 7 mg/mL 2 mg/mL
S6549 PBTZ169 <1 mg/mL 5 mg/mL 4 mg/mL
S9303 Saikosaponin B2 -1 mg/mL 100 mg/mL -1 mg/mL
S0349 Inarigivir soproxil 25 mg/mL 100 mg/mL '''''60 mg/mL
S9018 Luteoloside -1 mg/mL 89 mg/mL -1 mg/mL
S7775 Emricasan (IDN-6556) <1 mg/mL 100 mg/mL ''100 mg/mL
S7273 SC75741 <1 mg/mL 35 mg/mL <1 mg/mL
S8068 Chaetocin <1 mg/mL 100 mg/mL <1 mg/mL
S9063 Harringtonine -1 mg/mL 100 mg/mL -1 mg/mL
S4430 Hydroxychloroquine Sulfate (NSC 4375) 67 mg/mL <1 mg/mL '<1 mg/mL
S9064 Trilobatin -1 mg/mL 87 mg/mL -1 mg/mL
S4303 9-Aminoacridine <1 mg/mL 38 mg/mL '38 mg/mL
S5704 Myclobutanil -1 mg/mL 58 mg/mL -1 mg/mL
S0147 KKL-10 <1 mg/mL 3 mg/mL <1 mg/mL
S4983 Sorbic acid <1 mg/mL 22 mg/mL 22 mg/mL
S9070 Isoxanthohumol -1 mg/mL 70 mg/mL -1 mg/mL
S4198 Aminothiazole 20 mg/mL 20 mg/mL 20 mg/mL
S5927 Proguanil <1 mg/mL 51 mg/mL '51 mg/mL
S3710 Fosfomycin calcium <1 mg/mL 0.1 mg/mL <1 mg/mL
S5166 Benzoyleneurea -1 mg/mL 32 mg/mL -1 mg/mL
S8932 Remdesivir (GS-5734) <1 mg/mL 100 mg/mL '''16 mg/mL
S6771 MAC-545496 ˂1 mg/mL 84 mg/mL ˂1 mg/mL
S4104 Diminazene Aceturate 100 mg/mL 19 mg/mL <1 mg/mL
S4105 Closantel Sodium <1 mg/mL 100 mg/mL 100 mg/mL
S4106 Closantel <1 mg/mL 100 mg/mL <1 mg/mL
S3711 Carbasalate Calcium 91 mg/mL 11 mg/mL <1 mg/mL
S6689 Merimepodib <1 mg/mL 90 mg/mL <1 mg/mL
S4701 2-Deoxy-D-glucose (2-DG) 32 mg/mL 32 mg/mL '1 mg/mL
S9341 3,4-Dimethoxycinnamic acid -1 mg/mL 42 mg/mL -1 mg/mL
S0433 Nucleozin <1 mg/mL 15 mg/mL <1 mg/mL
S0195 Walrycin B ' mg/mL
S0436 Pleconaril ˂1 mg/mL 76 mg/mL 76 mg/mL
S4515 Ademetionine disulfate tosylate 79 mg/mL 79 mg/mL <1 mg/mL
S3028 Geneticin (G418 Sulfate) 100 mg/mL <1 mg/mL <1 mg/mL
S7417 Puromycin (CL13900) 2HCl 100 mg/mL 100 mg/mL ''<1 mg/mL
S4780 7-Methoxy-4-methylcoumarin -1 mg/mL 38 mg/mL -1 mg/mL
S4783 Benzyl isothiocyanate -1 mg/mL 29 mg/mL -1 mg/mL
S7867 Oleuropein 100 mg/mL 100 mg/mL 100 mg/mL
S0467 Emodepside <1 mg/mL 100 mg/mL 20 mg/mL
S0470 RSV604 ˂1 mg/mL 78 mg/mL '9 mg/mL
S4549 Antimonyl potassium tartrate trihydrate 100 mg/mL <1 mg/mL <1 mg/mL
S6814 GS-441524 <1 mg/mL 58 mg/mL <1 mg/mL
S5183 PD 169316 <1 mg/mL 14 mg/mL <1 mg/mL
S7419 Blasticidin S HCl 91 mg/mL <1 mg/mL <1 mg/mL
S7465 FTI 277 HCl 17 mg/mL 96 mg/mL '14 mg/mL
S4854 Bedaquiline fumarate <1 mg/mL 100 mg/mL 4 mg/mL
S1958 Sulbactam 47 mg/mL 47 mg/mL 47 mg/mL
S3288 Absinthin -1 mg/mL 10 mg/mL -1 mg/mL
S5184 Dexamethasone palmitate <1 mg/mL 100 mg/mL ''100 mg/mL
S3251 Goitrin -1 mg/mL 100 mg/mL -1 mg/mL
S3269 Acetylcorynoline -1 mg/mL 40 mg/mL -1 mg/mL
S3270 Genipin 1-O-beta-D-gentiobioside -1 mg/mL 100 mg/mL -1 mg/mL
S3279 Polyphyllin B (Formosanin C) -1 mg/mL 100 mg/mL -1 mg/mL
S0796 JNJ-632 <1 mg/mL 76 mg/mL '''76 mg/mL
S1208 Doxorubicin (Adriamycin) HCl 20 mg/mL 100 mg/mL ''<1 mg/mL
S5235 Cefodizime <1 mg/mL 100 mg/mL ''<1 mg/mL
S5417 Spectinomycin dihydrochloride pentahydrate 99 mg/mL 99 mg/mL ''11 mg/mL
S5330 Amikacin Sulfate Salt 100 mg/mL <1 mg/mL ''<1 mg/mL
S5961 Prednisolone disodium phosphate 97 mg/mL 97 mg/mL '''<1 mg/mL
S5968 Kasugamycin hydrochloride hydrate 87 mg/mL <1 mg/mL '''<1 mg/mL
S5963 Sulfathiazole sodium 55 mg/mL 55 mg/mL ''<1 mg/mL
P1201 LL37 (Human cathelicidin) 50 mg/mL -1 mg/mL -1 mg/mL
S3350 Cholesteryl linoleate 100 mg/mL 100 mg/mL '''100 mg/mL
S3364 3-Hydroxyphenylacetic acid 30 mg/mL 30 mg/mL '''30 mg/mL
S2869 Adamantane <1 mg/mL <1 mg/mL 15 mg/mL
S3218 Amiloxate ' mg/mL
S3280 Linderene -1 mg/mL 100 mg/mL -1 mg/mL
S3210 3'-Hydroxy-4'-methoxyacetophenone <1 mg/mL 33 mg/mL 33 mg/mL
S0906 6-Methoxydihydroavicine <1 mg/mL 73 mg/mL 1.5 mg/mL
S6854 Triazavirin 20 mg/mL 57 mg/mL <1 mg/mL
S3013 Plerixafor (AMD3100) 8HCl 100 mg/mL <1 mg/mL <1 mg/mL
S1373 Daptomycin (LY146032) 100 mg/mL 100 mg/mL '<1 mg/mL
S1408 Linezolid (PNU-100766) <1 mg/mL 67 mg/mL '8 mg/mL
S1097 BTZ043 Racemate <1 mg/mL 22 mg/mL <1 mg/mL
S1403 Tigecycline (GAR-936) 100 mg/mL 100 mg/mL '<1 mg/mL
S2504 Ribavirin (ICN-1229) 49 mg/mL 49 mg/mL '<1 mg/mL
S1807 Aciclovir (BW 248U) <1 mg/mL 45 mg/mL '<1 mg/mL
S1374 Doripenem Hydrate 26 mg/mL 36 mg/mL <1 mg/mL
S1381 Meropenem 8 mg/mL 76 mg/mL <1 mg/mL
S1162 Pretomanid (PA-824) <1 mg/mL 72 mg/mL 16 mg/mL
S1934 Nystatin (Fungicidin) <1 mg/mL 19 mg/mL <1 mg/mL
S1741 Rifabutin (LM427) <1 mg/mL 60 mg/mL '40 mg/mL
S1370 Biapenem 16 mg/mL <1 mg/mL <1 mg/mL
S1371 Cefoselis Sulfate 5 mg/mL 3 mg/mL <1 mg/mL
S2159 Tebipenem Pivoxil <1 mg/mL 99 mg/mL 87 mg/mL
S1636 Amphotericin B <1 mg/mL 22 mg/mL <1 mg/mL
S1282 Artemisinin <1 mg/mL 57 mg/mL 24 mg/mL
S1399 Teicoplanin 100 mg/mL <1 mg/mL <1 mg/mL
S1505 Aztreonam 11 mg/mL 87 mg/mL <1 mg/mL
S1725 Terbinafine <1 mg/mL 58 mg/mL 58 mg/mL
S2510 Spectinomycin 2HCl 81 mg/mL 81 mg/mL <1 mg/mL
S1768 Cefditoren Pivoxil <1 mg/mL 100 mg/mL <1 mg/mL
S1839 Chloroxine <1 mg/mL 43 mg/mL <1 mg/mL
S2264 Artemether <1 mg/mL 60 mg/mL 60 mg/mL
S1998 D-Cycloserine 20 mg/mL <1 mg/mL <1 mg/mL
S2479 Lincomycin HCl 89 mg/mL 89 mg/mL <1 mg/mL
S1605 Cefdinir <1 mg/mL 79 mg/mL <1 mg/mL
S2152 Sitafloxacin Hydrate <1 mg/mL 4 mg/mL <1 mg/mL
S1502 Cephalexin 10 mg/mL 1 mg/mL <1 mg/mL
S1835 Azithromycin (CP-62993) <1 mg/mL 100 mg/mL '100 mg/mL
S1773 Oxytetracycline (Terramycin) <1 mg/mL 92 mg/mL 10 mg/mL
S1637 Docosanol <1 mg/mL <1 mg/mL 4 mg/mL
S2568 Neomycin sulfate 143 mg/mL <1 mg/mL '<1 mg/mL
S1777 Ethionamide <1 mg/mL 33 mg/mL 17 mg/mL
S1635 Erythromycin 3 mg/mL 147 mg/mL 147 mg/mL
S2420 Aloperine 12 mg/mL 2 mg/mL 46 mg/mL
S4226 Minocycline (CL 59806) HCl 1 mg/mL <1 mg/mL '<1 mg/mL
S2486 Moroxydine HCl 42 mg/mL 42 mg/mL <1 mg/mL
S1644 Nitrofural <1 mg/mL 40 mg/mL <1 mg/mL
S3079 Atovaquone <1 mg/mL 5 mg/mL <1 mg/mL
S4052 Netilmicin Sulfate 288 mg/mL <1 mg/mL <1 mg/mL
S4082 Spiramycin <1 mg/mL 100 mg/mL 100 mg/mL
S2565 Amoxicillin Sodium 78 mg/mL 78 mg/mL <1 mg/mL
S2544 Cefprozil hydrate <1 mg/mL <1 mg/mL <1 mg/mL
S2563 Oxacillin sodium monohydrate 88 mg/mL <1 mg/mL <1 mg/mL
S3129 Trimethoprim <1 mg/mL 58 mg/mL '<1 mg/mL
S2028 Diclazuril <1 mg/mL 16 mg/mL <1 mg/mL
S1499 Cefaclor <1 mg/mL 11 mg/mL '<1 mg/mL
S1915 Sulfamethoxazole <1 mg/mL 51 mg/mL 23 mg/mL
S2120 Arbidol HCl <1 mg/mL 103 mg/mL 22 mg/mL
S2467 Famciclovir 64 mg/mL 64 mg/mL 48 mg/mL
S2574 Tetracycline HCl 96 mg/mL 96 mg/mL <1 mg/mL
S2575 Vancomycin HCl 100 mg/mL <1 mg/mL <1 mg/mL
S1851 Oxibendazole <1 mg/mL 1 mg/mL <1 mg/mL
S2501 Pyrantel Pamoate <1 mg/mL 100 mg/mL <1 mg/mL
S4030 Gentamicin Sulfate 100 mg/mL <1 mg/mL <1 mg/mL
S2514 Tobramycin 94 mg/mL <1 mg/mL <1 mg/mL
S1762 Pyrazinamide 12 mg/mL 25 mg/mL 2 mg/mL
S2530 7-Aminocephalosporanic acid <1 mg/mL 1 mg/mL <1 mg/mL
S2543 Ceftiofur HCl <1 mg/mL 100 mg/mL 22 mg/mL
S1691 Praziquantel <1 mg/mL 63 mg/mL 63 mg/mL
S4237 Primaquine Diphosphate 91 mg/mL 91 mg/mL <1 mg/mL
S1964 Rimantadine 33 mg/mL 33 mg/mL 33 mg/mL
S1883 Idoxuridine <1 mg/mL 35 mg/mL <1 mg/mL
S3162 Tylosin tartrate 200 mg/mL 300 mg/mL 300 mg/mL
S1916 Sulfisoxazole <1 mg/mL 53 mg/mL 2 mg/mL
S1770 Sulfadiazine <1 mg/mL 50 mg/mL <1 mg/mL
S3195 Azlocillin sodium salt 97 mg/mL 97 mg/mL 3 mg/mL
S4004 Ethambutol 2HCl 56 mg/mL 56 mg/mL <1 mg/mL
S2469 Fleroxacin <1 mg/mL <1 mg/mL <1 mg/mL
S3116 Sulfathiazole <1 mg/mL 51 mg/mL <1 mg/mL
S2506 Roxithromycin <1 mg/mL 167 mg/mL 167 mg/mL
S2048 Clindamycin Phosphate 101 mg/mL <1 mg/mL <1 mg/mL
S3055 Besifloxacin HCl 1 mg/mL <1 mg/mL <1 mg/mL
S2511 Sulfadoxine <1 mg/mL 62 mg/mL <1 mg/mL
S3067 Chlorhexidine 2HCl <1 mg/mL 100 mg/mL <1 mg/mL
S3059 Enrofloxacin <1 mg/mL 3 mg/mL <1 mg/mL
S4141 Dinitolmide <1 mg/mL 45 mg/mL 1 mg/mL
S1977 Sarafloxacin HCl <1 mg/mL 4 mg/mL <1 mg/mL
S4146 Bacitracin 100 mg/mL -1 mg/mL -1 mg/mL
S4147 Azithromycin Dihydrate 10 mg/mL 100 mg/mL 100 mg/mL
S4254 Apramycin Sulfate 100 mg/mL <1 mg/mL '<1 mg/mL
S4056 Retapamulin <1 mg/mL 104 mg/mL 104 mg/mL
S3015 Amoxicillin <1 mg/mL 73 mg/mL <1 mg/mL
S4184 Penciclovir 1 mg/mL 34 mg/mL <1 mg/mL
S4191 Betamipron <1 mg/mL 39 mg/mL 39 mg/mL
S1957 Sulfamethizole <1 mg/mL 54 mg/mL 10 mg/mL
S2537 Secnidazole 37 mg/mL 37 mg/mL 37 mg/mL
S4195 Broxyquinoline <1 mg/mL 17 mg/mL <1 mg/mL
S4196 Ethacridine lactate monohydrate 5 mg/mL 72 mg/mL <1 mg/mL
S4093 Bismuth Subcitrate Potassium 100 mg/mL <1 mg/mL <1 mg/mL
S4094 Tetramisole HCl 41 mg/mL <1 mg/mL <1 mg/mL
S2539 Lomefloxacin HCl 6 mg/mL 1 mg/mL <1 mg/mL
S2612 Ribitol 30 mg/mL 30 mg/mL <1 mg/mL
S3122 Amikacin hydrate 100 mg/mL <1 mg/mL <1 mg/mL
S3105 Nadifloxacin <1 mg/mL 20 mg/mL <1 mg/mL
S4234 Capreomycin Sulfate 100 mg/mL <1 mg/mL <1 mg/mL
S3133 Sulfamethazine <1 mg/mL 56 mg/mL <1 mg/mL
S1855 Pefloxacin Mesylate 67 mg/mL 14 mg/mL <1 mg/mL
S3179 Carbenicillin disodium 84 mg/mL 5 mg/mL <1 mg/mL
S3193 Ticarcillin sodium 86 mg/mL 86 mg/mL '<1 mg/mL
S1881 Protionamide <1 mg/mL 36 mg/mL 7 mg/mL
S1830 Oxfendazole <1 mg/mL 10 mg/mL <1 mg/mL
S4726 Lauric Acid 20 mg/mL 40 mg/mL 40 mg/mL
S5227 Erythromycin thiocyanate -1 mg/mL 100 mg/mL -1 mg/mL
S3941 Pinocembrin <1 mg/mL 51 mg/mL 51 mg/mL
S5352 Cefminox Sodium 100 mg/mL 100 mg/mL ''<1 mg/mL
S6235 Sodium dehydroacetate -1 mg/mL 38 mg/mL -1 mg/mL
S8071 UNC0638 6 mg/mL 100 mg/mL 100 mg/mL
S3621 Pazufloxacin mesylate 82 mg/mL 82 mg/mL '7 mg/mL
S5560 Midecamycin <1 mg/mL 100 mg/mL 100 mg/mL
S3999 α-santonin -1 mg/mL 49 mg/mL -1 mg/mL
S5406 Sultamicillin Tosylate 9 mg/mL 100 mg/mL 100 mg/mL
S5048 Fosfomycin Disodium 36 mg/mL <1 mg/mL -1 mg/mL
S5051 Pipemidic acid 60 mg/mL <1 mg/mL '-1 mg/mL
S5328 Gamithromycin <1 mg/mL 100 mg/mL '100 mg/mL
S4576 Sulfabenzamide <1 mg/mL 55 mg/mL <1 mg/mL
S5353 Cefpiramide sodium 100 mg/mL 100 mg/mL <1 mg/mL
S4848 Dalbavancin 100 mg/mL 100 mg/mL ''<1 mg/mL
S5081 Ceforanide -1 mg/mL 6 mg/mL -1 mg/mL
S5951 Cefoxitin <1 mg/mL 85 mg/mL 85 mg/mL
S5035 6-Aminopenicillanic acid <1 mg/mL 1 mg/mL <1 mg/mL
S5356 Ceftiofur -1 mg/mL 100 mg/mL -1 mg/mL
S9564 p-Hydroxy-cinnamic Acid <1 mg/mL 33 mg/mL 33 mg/mL
S5012 Octenidine Dihydrochloride -1 mg/mL 60 mg/mL -1 mg/mL
S2583 Thiamphenicol <1 mg/mL 71 mg/mL <1 mg/mL
S3623 Ceftibuten dihydrate -1 mg/mL 90 mg/mL -1 mg/mL
S6288 Chlorhexidine diacetate -1 mg/mL 100 mg/mL -1 mg/mL
S4850 Flucloxacillin sodium 95 mg/mL 95 mg/mL 5 mg/mL
S9224 Dehydroandrographolide Succinate -1 mg/mL 100 mg/mL -1 mg/mL
S4846 Meropenem Trihydrate 87 mg/mL 87 mg/mL 4 mg/mL
S5533 Tobramycin sulfate 100 mg/mL <1 mg/mL -1 mg/mL
S9226 Steviolbioside -1 mg/mL 100 mg/mL -1 mg/mL
S4594 Cephalothin sodium 83 mg/mL 10 mg/mL ''''<1 mg/mL
S4865 Cefetamet pivoxil hydrochloride <1 mg/mL 100 mg/mL 100 mg/mL
S5941 Besifloxacin <1 mg/mL <1 mg/mL <1 mg/mL
S4866 Nicarbazin <1 mg/mL 9 mg/mL <1 mg/mL
S5366 Fipronil -1 mg/mL 87 mg/mL -1 mg/mL
S4420 Mefloquine HCl <1 mg/mL 82 mg/mL 82 mg/mL
S4880 Cefathiamidine -1 mg/mL 94 mg/mL -1 mg/mL
S5531 Doripenem -1 mg/mL 60 mg/mL -1 mg/mL
S3971 Fusidine -1 mg/mL 100 mg/mL -1 mg/mL
S1617 Sulfapyridine <1 mg/mL 2 mg/mL <1 mg/mL
S5332 Cefquinome sulfate 9 mg/mL 100 mg/mL <1 mg/mL
S5278 Tedizolid (TR-700) -1 mg/mL 10 mg/mL -1 mg/mL
S4029 Colistin Sulfate 100 mg/mL <1 mg/mL <1 mg/mL
S4122 Tilmicosin 8 mg/mL 100 mg/mL <1 mg/mL
S2052 Oxytetracycline Dihydrate <1 mg/mL 5 mg/mL <1 mg/mL
S5532 Erythromycin estolate -1 mg/mL 100 mg/mL -1 mg/mL
S5535 Moxifloxacin -1 mg/mL 24 mg/mL -1 mg/mL
S5684 Lapachol -1 mg/mL 48 mg/mL -1 mg/mL
S4876 Robenidine Hydrochloride -1 mg/mL 74 mg/mL -1 mg/mL
S5625 Ammonium lactate ' mg/mL
S4869 Sulfamethoxazole sodium -1 mg/mL 55 mg/mL -1 mg/mL
S5719 Ceftizoxime sodium 81 mg/mL 81 mg/mL <1 mg/mL
S5054 Rifamycin sodium salt -1 mg/mL 100 mg/mL -1 mg/mL
S5207 Cephalexin Monohydrate <1 mg/mL 0.01 mg/mL <1 mg/mL
S4585 Succinylsulfathiazole <1 mg/mL 71 mg/mL '<1 mg/mL
S5491 Lomefloxacin -1 mg/mL 7 mg/mL -1 mg/mL
S4142 Clopidol <1 mg/mL 1 mg/mL <1 mg/mL
S4592 Captisol (SBE-β-CD) 100 mg/mL <1 mg/mL <1 mg/mL
S5331 Ceftezole sodium 92 mg/mL 92 mg/mL <1 mg/mL
S4595 Cefazolin Sodium 95 mg/mL 95 mg/mL '<1 mg/mL
S5333 Sulbenicillin Sodium 91 mg/mL 91 mg/mL '<1 mg/mL
S5936 Cefazolin <1 mg/mL 91 mg/mL <1 mg/mL
S4145 Decoquinate <1 mg/mL 0.01 mg/mL <1 mg/mL
S4596 Cefixime <1 mg/mL 90 mg/mL 1 mg/mL
S5700 Phthalylsulfathiazole -1 mg/mL 80 mg/mL '-1 mg/mL
S4148 Ampicillin Trihydrate 2 mg/mL 81 mg/mL <1 mg/mL
S4041 Olsalazine Sodium 41 mg/mL 4 mg/mL <1 mg/mL
S4150 Orbifloxacin <1 mg/mL 0.05 mg/mL <1 mg/mL
S4875 Cephapirin Benzathine -1 mg/mL 81 mg/mL -1 mg/mL
S4421 Josamycin ' mg/mL
S4885 Taurolidine -1 mg/mL 56 mg/mL -1 mg/mL
S4250 Sulfamethoxypyridazine <1 mg/mL 56 mg/mL '<1 mg/mL
S9278 Saikosaponin C -1 mg/mL 100 mg/mL -1 mg/mL
S5397 Chlorhexidine -1 mg/mL 100 mg/mL -1 mg/mL
S4156 Chlortetracycline HCl (NSC 13252) 1 mg/mL 5 mg/mL '''<1 mg/mL
S4158 Ceftriaxone disodium salt hemi (heptahydrate) 100 mg/mL 1 mg/mL <1 mg/mL
S4160 Penicillin G Sodium 71 mg/mL 71 mg/mL <1 mg/mL
S2271 Berberine chloride (NSC 646666) <1 mg/mL 40 mg/mL <1 mg/mL
S4942 4-Hydroxy-3,5-dimethoxybenzyl alcohol -1 mg/mL 36 mg/mL '-1 mg/mL
S5492 Econazole -1 mg/mL 76 mg/mL -1 mg/mL
S4874 Cefazedone -1 mg/mL 100 mg/mL -1 mg/mL
S9466 Methenamine Hippurate -1 mg/mL 14 mg/mL -1 mg/mL
S2282 Cinchonidine <1 mg/mL 59 mg/mL 59 mg/mL
S5475 Novaluron -1 mg/mL 99 mg/mL '-1 mg/mL
S9292 Dictamnine -1 mg/mL 33 mg/mL -1 mg/mL
S5296 Cephradine monohydrate 4 mg/mL <1 mg/mL -1 mg/mL
S5290 Ormetoprim <1 mg/mL 0.01 mg/mL <1 mg/mL
S5487 Cefoperazone sodium -1 mg/mL 100 mg/mL -1 mg/mL
S4610 Mebendazole <1 mg/mL 6 mg/mL <1 mg/mL
S4822 Silver Sulfadiazine <1 mg/mL 0.1 mg/mL <1 mg/mL
S5294 Cephalotin acid -1 mg/mL 79 mg/mL '-1 mg/mL
S5736 Benzathine penicilline -1 mg/mL 100 mg/mL -1 mg/mL
S4167 Cyromazine 1 mg/mL 33 mg/mL 2 mg/mL
S4612 Dapson <1 mg/mL 49 mg/mL '10 mg/mL
S1884 Sparfloxacin <1 mg/mL 9 mg/mL <1 mg/mL
S5722 Oxantel Pamoate -1 mg/mL 100 mg/mL -1 mg/mL
S1395 Polymyxin B sulphate 100 mg/mL <1 mg/mL <1 mg/mL
S2385 Hordenine <1 mg/mL 33 mg/mL 33 mg/mL
S4634 Sodium sulfadiazine 54 mg/mL 9 mg/mL '<1 mg/mL
S4959 Skatole -1 mg/mL 26 mg/mL -1 mg/mL
S5601 Balofloxacin Dihydrate <1 mg/mL 2 mg/mL 2 mg/mL
S4172 Cetylpyridinium Chloride 68 mg/mL 68 mg/mL 68 mg/mL
S4641 Tedizolid Phosphate <1 mg/mL 22 mg/mL <1 mg/mL
S6243 Ethyl pyruvate ' mg/mL
S3695 Cystamine dihydrochloride 45 mg/mL 14 mg/mL '2 mg/mL
S5291 sulfaisodimidine -1 mg/mL 55 mg/mL -1 mg/mL
S4175 Sulfaguanidine <1 mg/mL 43 mg/mL <1 mg/mL
S2395 Rheochrysidin <1 mg/mL 1 mg/mL <1 mg/mL
S3787 Picroside I -1 mg/mL 98 mg/mL -1 mg/mL
S3645 Kitasamycin <1 mg/mL 100 mg/mL '100 mg/mL
S6562 KKL-35 <1 mg/mL 32 mg/mL <1 mg/mL
S3644 Sulfamonomethoxine <1 mg/mL 56 mg/mL 4 mg/mL
S9016 Dipsacoside B -1 mg/mL 100 mg/mL -1 mg/mL
S5298 Amoxicillin trihydrate -1 mg/mL 30 mg/mL -1 mg/mL
S5546 Sulfacetamide -1 mg/mL 43 mg/mL -1 mg/mL
S5908 Garenoxacin <1 mg/mL 2 mg/mL <1 mg/mL
S4179 Mezlocillin Sodium 100 mg/mL 100 mg/mL <1 mg/mL
S4060 Erythromycin Ethylsuccinate <1 mg/mL 172 mg/mL 172 mg/mL
S5515 Penicillin G Procaine -1 mg/mL 100 mg/mL -1 mg/mL
S3649 Ceftazidime 100 mg/mL 4 mg/mL <1 mg/mL
S5289 Ceftezole -1 mg/mL 88 mg/mL '-1 mg/mL
S4062 Ronidazole <1 mg/mL 40 mg/mL <1 mg/mL
S4183 Paromomycin Sulfate 100 mg/mL <1 mg/mL <1 mg/mL
S3655 Cefepime Dihydrochloride Monohydrate 1 mg/mL 100 mg/mL <1 mg/mL
S5020 Tilorone dihydrochloride 96 mg/mL 43 mg/mL '96 mg/mL
S5637 Cefotiam Hexetil Hydrochloride -1 mg/mL 100 mg/mL -1 mg/mL
S4541 Triclosan <1 mg/mL 57 mg/mL 57 mg/mL
S4971 Buparvaquone <1 mg/mL 65 mg/mL '4 mg/mL
S5638 Cefozopran hydrochloride -1 mg/mL 100 mg/mL ''''-1 mg/mL
S5299 Tosufloxacin p-Toluenesulfonate Hydrate -1 mg/mL 100 mg/mL -1 mg/mL
S5644 Ceftriaxone Sodium -1 mg/mL 100 mg/mL -1 mg/mL
S4720 Cefotaxime <1 mg/mL 91 mg/mL <1 mg/mL
S4898 Sulfalozine sodium -1 mg/mL 56 mg/mL -1 mg/mL
S5295 Lincomycin Hydrochloride Monohydrate -1 mg/mL 92 mg/mL -1 mg/mL
S6761 Dalfopristin <1 mg/mL 100 mg/mL ''''100 mg/mL
S8871 Omadacycline tosylate 100 mg/mL 100 mg/mL 100 mg/mL
S4068 Tinidazole <1 mg/mL 49 mg/mL <1 mg/mL
S3676 Carbendazim <1 mg/mL 17 mg/mL <1 mg/mL
S2315 Kanamycin sulfate 52 mg/mL <1 mg/mL <1 mg/mL
S4192 Chlorquinaldol <1 mg/mL 46 mg/mL 6 mg/mL
S5420 Clindamycin alcoholate -1 mg/mL 95 mg/mL -1 mg/mL
S5816 pyrvinium <1 mg/mL 22 mg/mL <1 mg/mL
S4882 Resorantel -1 mg/mL 61 mg/mL -1 mg/mL
S5421 Fluoroquinolonic Acid -1 mg/mL 25 mg/mL '-1 mg/mL
S5292 Diazolidinyl urea -1 mg/mL 55 mg/mL -1 mg/mL
S6423 Tildipirosin -1 mg/mL 100 mg/mL -1 mg/mL
S4750 Sulfacetamide sodium salt hydrate 50 mg/mL 50 mg/mL 2 mg/mL
S5017 Oxyclozanide -1 mg/mL 80 mg/mL '-1 mg/mL
S9046 Berberine 1 mg/mL 45 mg/mL 5 mg/mL
S6582 Ozenoxacin <1 mg/mL 5 mg/mL <1 mg/mL
S8627 OSS_128167 <1 mg/mL 73 mg/mL <1 mg/mL
S4870 Cefodizime Sodium -1 mg/mL 100 mg/mL -1 mg/mL
S5887 Khellin <1 mg/mL 26 mg/mL 7 mg/mL
S4081 Sulfacetamide Sodium 51 mg/mL 19 mg/mL <1 mg/mL
S3636 Cefadroxil hydrate 1 mg/mL 7 mg/mL <1 mg/mL
S3637 Cefpirome sulfate 100 mg/mL 100 mg/mL <1 mg/mL
S4759 p-Coumaric Acid <1 mg/mL 32 mg/mL '32 mg/mL
S3638 Cefamandole nafate 100 mg/mL 100 mg/mL <1 mg/mL
S5440 Berberine Sulfate -1 mg/mL 20 mg/mL -1 mg/mL
S5948 Amodiaquine <1 mg/mL 71 mg/mL 22 mg/mL
S5016 Isoprinosine 100 mg/mL 100 mg/mL 2 mg/mL
S4978 Azathramycin <1 mg/mL 50 mg/mL '100 mg/mL
S3713 Moxidectin <1 mg/mL 100 mg/mL '100 mg/mL
S7411 Ascomycin (FK520) <1 mg/mL 100 mg/mL 100 mg/mL
S0146 Broxaldine <1 mg/mL 30 mg/mL <1 mg/mL
S1450 Nanchangmycin <1 mg/mL 100 mg/mL 100 mg/mL
S5784 Vancomycin <1 mg/mL 29 mg/mL <1 mg/mL
S9387 Maackiain -1 mg/mL 56 mg/mL -1 mg/mL
S3707 Ethopabate <1 mg/mL 47 mg/mL '47 mg/mL
S3708 Sulfachloropyridazine <1 mg/mL 56 mg/mL 9 mg/mL
S4201 Florfenicol <1 mg/mL 72 mg/mL 8 mg/mL
S4663 Fusidate Sodium 100 mg/mL 100 mg/mL 100 mg/mL
S3709 Furagin <1 mg/mL 52 mg/mL '<1 mg/mL
S5041 Difloxacin hydrochloride 98 mg/mL 98 mg/mL 98 mg/mL
S4203 Furaltadone HCl 72 mg/mL 17 mg/mL <1 mg/mL
S5657 Ertapenem sodium 100 mg/mL 100 mg/mL <1 mg/mL
S9078 Epigoitrin -1 mg/mL 4.89 mg/mL -1 mg/mL
S4986 Latamoxef sodium 100 mg/mL 100 mg/mL '<1 mg/mL
S9084 Rhoifolin -1 mg/mL 100 mg/mL -1 mg/mL
S6411 Nimorazole -1 mg/mL 45 mg/mL -1 mg/mL
S3058 Danofloxacin Mesylate 91 mg/mL <1 mg/mL <1 mg/mL
S4271 Isepamicin Sulphate 100 mg/mL <1 mg/mL <1 mg/mL
S3672 Cefonicid sodium 100 mg/mL 100 mg/mL ''<1 mg/mL
S4213 Dirithromycin <1 mg/mL 11 mg/mL 100 mg/mL
S6729 Besifovir 60 mg/mL 60 mg/mL 2 mg/mL
S4215 Ribostamycin Sulfate 100 mg/mL <1 mg/mL <1 mg/mL
S4216 Valnemulin HCl 100 mg/mL 100 mg/mL 100 mg/mL
S5055 Milbemycin Oxime <1 mg/mL 100 mg/mL 100 mg/mL
S4671 Cefradine 10 mg/mL <1 mg/mL <1 mg/mL
S5070 Mupirocin calcium 6 mg/mL 100 mg/mL '100 mg/mL
S6067 2,4-dichlorobenzyl alcohol -1 mg/mL 35 mg/mL -1 mg/mL
S6068 Doxycycline monohydrate -1 mg/mL 47 mg/mL -1 mg/mL
S5724 Dichlorophen -1 mg/mL 54 mg/mL '-1 mg/mL
S2334 Oleanolic Acid <1 mg/mL 21 mg/mL 7 mg/mL
S9099 Orientin -1 mg/mL 89 mg/mL -1 mg/mL
S2335 Oridonin (NSC-250682) <1 mg/mL 72 mg/mL 28 mg/mL
S3801 Sodium Houttuyfonate <1 mg/mL 2 mg/mL <1 mg/mL
S5776 Proflavine <1 mg/mL 23 mg/mL 2 mg/mL
S6444 Triclocarban <1 mg/mL 63 mg/mL 5 mg/mL
S4222 Piperacillin Sodium 100 mg/mL 100 mg/mL 100 mg/mL
S3650 Penicillin V potassium salt 77 mg/mL <1 mg/mL <1 mg/mL
S2613 Clorsulon <1 mg/mL 76 mg/mL 7 mg/mL
S9328 5,6,7-Trimethoxyflavone -1 mg/mL 10 mg/mL -1 mg/mL
S5036 Nisin 6.7 mg/mL 7 mg/mL <1 mg/mL
S6442 Chlorphenesin 10 mg/mL 41 mg/mL 41 mg/mL
S9342 1,4-Naphthoquinone -1 mg/mL 32 mg/mL -1 mg/mL
S2564 Cloxacillin Sodium 55 mg/mL 55 mg/mL 25 mg/mL
S3121 Ornidazole 2 mg/mL 44 mg/mL 44 mg/mL
S9112 Kaempferitrin -1 mg/mL 100 mg/mL -1 mg/mL
S5096 SulfadiMethoxine sodium -1 mg/mL 66 mg/mL '-1 mg/mL
S9113 Ononin -1 mg/mL 86 mg/mL -1 mg/mL
S6464 Ftaxilide <1 mg/mL 54 mg/mL 13 mg/mL
S5924 Olanexidine Hydrochloride semihydrate <1 mg/mL 82 mg/mL 82 mg/mL
S6459 Nifurtimox <1 mg/mL 57 mg/mL <1 mg/mL
S4232 Nithiamide <1 mg/mL 37 mg/mL <1 mg/mL
S3618 Acetylspiramycin (ASPM) <1 mg/mL 100 mg/mL '15 mg/mL
S9120 Scutellarein -1 mg/mL 57 mg/mL -1 mg/mL
S5410 Chloramphenicol sodium succinate -1 mg/mL 89 mg/mL -1 mg/mL
S4517 Cefotaxime sodium 95 mg/mL 95 mg/mL <1 mg/mL
S9122 Tectorigenin -1 mg/mL 60 mg/mL -1 mg/mL
S4518 Chloroxylenol <1 mg/mL 31 mg/mL 31 mg/mL
S5209 Enoxacin Sesquihydrate -1 mg/mL 4 mg/mL '-1 mg/mL
S3132 Sulfamerazine <1 mg/mL 53 mg/mL <1 mg/mL
S4236 Proflavine Hemisulfate 22 mg/mL <1 mg/mL <1 mg/mL
S5208 Ciprofloxacin hydrochloride hydrate -1 mg/mL 8 mg/mL -1 mg/mL
S5573 Tilmicosin phosphate -1 mg/mL 100 mg/mL -1 mg/mL
S3065 Amikacin disulfate 10 mg/mL <1 mg/mL <1 mg/mL
S4523 Dihydrostreptomycin sulfate 100 mg/mL <1 mg/mL <1 mg/mL
S3746 Lumefantrine <1 mg/mL 13 mg/mL <1 mg/mL
S5212 Imidazolidinyl Urea -1 mg/mL 77 mg/mL '-1 mg/mL
S5473 Pivmecillinam hydrochloride 95 mg/mL 95 mg/mL 95 mg/mL
S9444 Tomatine -1 mg/mL 100 mg/mL -1 mg/mL
S5210 Sulfamethazine Sodium Salt -1 mg/mL 60 mg/mL -1 mg/mL
S0443 Desciclovir 25 mg/mL 42 mg/mL '3 mg/mL
S4528 Furazolidone <1 mg/mL 45 mg/mL <1 mg/mL
S4678 Povidone iodine 28 mg/mL 28 mg/mL '28 mg/mL
S5201 Acetylisovaleryltylosin Tartrate -1 mg/mL 100 mg/mL '-1 mg/mL
S5206 Benzylpenicillin potassium -1 mg/mL 74 mg/mL -1 mg/mL
S9131 Punicalagin -1 mg/mL 100 mg/mL -1 mg/mL
S5211 4-Aminosalicylic acid -1 mg/mL 10 mg/mL '-1 mg/mL
S5094 Maduramycin Ammonium -1 mg/mL 100 mg/mL -1 mg/mL
S4833 Cefoxitin sodium 89 mg/mL 89 mg/mL <1 mg/mL
S4536 Nitrofurantoin <1 mg/mL 47 mg/mL <1 mg/mL
S9135 Artemisic acid -1 mg/mL 46 mg/mL -1 mg/mL
S5093 Rafoxanide -1 mg/mL 100 mg/mL '-1 mg/mL
S9136 Neochlorogenic acid -1 mg/mL 70 mg/mL -1 mg/mL
S3170 Ampicillin sodium 74 mg/mL 37 mg/mL 74 mg/mL
S5092 Febantel -1 mg/mL 89 mg/mL -1 mg/mL
S5350 Cefpodoxime proxetil <1 mg/mL 100 mg/mL 100 mg/mL
S4540 Sisomicin sulfate 100 mg/mL <1 mg/mL <1 mg/mL
S5405 Propylparaben <1 mg/mL 36 mg/mL 36 mg/mL
S4242 Cetrimonium Bromide (CTAB) 100 mg/mL 5 mg/mL 100 mg/mL
S5095 Olaquindox <1 mg/mL 0.01 mg/mL '<1 mg/mL
S5214 Imidocarb dipropionate -1 mg/mL 39 mg/mL -1 mg/mL
S6461 Permethrin <1 mg/mL 78 mg/mL 19 mg/mL
S3978 5-Phenyl-2,4-pentadienoic acid -1 mg/mL 6 mg/mL '-1 mg/mL
S5159 Doxycycline -1 mg/mL 88 mg/mL '-1 mg/mL
S4389 Bephenium Hydroxynaphthoate <1 mg/mL 88 mg/mL '<1 mg/mL
S4279 Demeclocycline HCl 26 mg/mL 100 mg/mL <1 mg/mL
S5390 N-(Hytroxymethy)micotinamide -1 mg/mL 30 mg/mL '-1 mg/mL
S5744 Spiramycin I -1 mg/mL 100 mg/mL -1 mg/mL
S4813 Cefuroxime axetil -1 mg/mL 100 mg/mL -1 mg/mL
S4393 Cephapirin Sodium ' mg/mL
S5354 Cefteram pivoxil <1 mg/mL 0.01 mg/mL <1 mg/mL
S4550 Azelaic acid 37 mg/mL 37 mg/mL '37 mg/mL
S4844 Cefcapene Pivoxil Hydrochloride -1 mg/mL 100 mg/mL -1 mg/mL
S5355 Piperaquine phosphate 2 mg/mL <1 mg/mL -1 mg/mL
S5351 Cefmetazole sodium 98 mg/mL 98 mg/mL 1 mg/mL
S9560 Anisodamine Hydrobromide -1 mg/mL 77 mg/mL -1 mg/mL
S5005 Cefotiam hydrochloride -1 mg/mL 100 mg/mL '-1 mg/mL
S4553 Bronopol 39 mg/mL 39 mg/mL 39 mg/mL
S5859 Sancycline <1 mg/mL 83 mg/mL '<1 mg/mL
S1962 Sulphadimethoxine <1 mg/mL 62 mg/mL <1 mg/mL
S5007 Delamanid <1 mg/mL 100 mg/mL '2 mg/mL
S4555 Carsalam <1 mg/mL 32 mg/mL 2 mg/mL
S4812 Ceftizoxime <1 mg/mL 76 mg/mL <1 mg/mL
S5863 Metronidazole Benzoate <1 mg/mL 55 mg/mL 13 mg/mL
S4404 Pasiniazid <1 mg/mL 58 mg/mL 15 mg/mL
S7896 Sodium Tauroursodeoxycholate (TUDC) 100 mg/mL 100 mg/mL 71 mg/mL
S4522 Dehydroacetic acid <1 mg/mL 33 mg/mL '33 mg/mL
S5108 Tylosin -1 mg/mL 100 mg/mL -1 mg/mL
S4408 Procodazole <1 mg/mL 38 mg/mL ''<1 mg/mL
S4847 Faropenem Sodium 61 mg/mL 12 mg/mL <1 mg/mL
S4565 Diiodohydroxyquinoline <1 mg/mL 13 mg/mL <1 mg/mL
S4999 Avermectin B1 -1 mg/mL 100 mg/mL -1 mg/mL
S9185 Nitidine Chloride -1 mg/mL 11 mg/mL -1 mg/mL
S5456 Isobavachalcone <1 mg/mL 64 mg/mL 64 mg/mL

Anti-infection製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1047

Vorinostat (SAHA)

Vorinostat (suberoylanilide hydroxamic acid, SAHA, MK0683) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay. Vorinostat abrogates productive HPV-18 DNA amplification.
Neuro Oncol, 2021, 23(3):376-386
Neuro Oncol, 2021, 23(2):226-239
Elife, 2021, 10e63810
S1009

Dactolisib (BEZ235)

Dactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3TopBP1-ER cell. Dactolisib induces autophagy and suppresses HIV-1 replication. Phase 2.
Cell Rep, 2021, 34(11):108870
Cell Rep, 2021, 35(1):108940
Oncogenesis, 2021, 10(1):8
S1102

U0126-EtOH

U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. U0126 inhibits autophagy and mitophagy with antiviral activity.
Theranostics, 2021, 11(3):996-1015
ACS Appl Mater Interfaces, 2021, 13(1):97-111
Cell Rep, 2021, 35(5):109069
S5001

Tofacitinib (CP-690550) Citrate

Tofacitinib citrate (CP-690550, Tasocitinib) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity.
Cancer Res, 2021, canres.2125.2020
Cell Rep, 2021, 34(3):108627
Arthritis Rheumatol, 2021, 10.1002/art.41666
S5979新

2',3'-Dideoxyadenosine

2',3'-Dideoxyadenosine (ddA, ddAdo) is an anti-human immunodeficiency virus agent against human immunodeficiency virus (HIV) and human hepatitis B virus (HBV) replication.
S5967新

Berberine chloride hydrate

Berberine (Natural Yellow 18) chloride hydrate is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.
S4974新

Oxacillin sodium

Oxacillin sodium (salt) is a narrow-spectrum β-lactam antibiotic that can be used for treatment of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia.
S5199新

Oxytetracycline hydrochloride

Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
S4490新

Tetracycline

Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.
S5186新

Cefpiramide

Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) is a pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.
S4979新

Procaine penicillin G

Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic.
S5008新

Ciprofloxacin hydrochloride

Ciprofloxacin (CPX, Cetraxal, Ciloxan, Cipro, Bay-09867) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).
S5495新

Ceftiofur sodium

Ceftiofur sodium is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.
S5959新

Tenofovir Disoproxil

Tenofovir Disoproxil (Bis(POC)-PMPA, GS 4331) is a prodrug of tenofovir, which is metabolised intracellularly to its active anabolite tenofovir diphosphate, a competitive inhibitor of HIV-1 reverse transcriptase and terminates the growing DNA chain.
S4879新

Tenofovir hydrate

Tenofovir (GS-1278) hydrate blocks reverse transcriptase and hepatitis B virus infections.
S4945新

Ethacridine lactate

Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
S4488新

Delafloxacin Meglumine

Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens.
S6584新

Amdinocillin

Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms.
S4446新

Dimercaprol

Dimercaprol (Bal, 2,3-Dimercapto-1-propanol, Dithioglycerol) is an acrolein scavenger that inhibits HIV-1 tat activity, viral production, and infectivity in vitro.
S4425新

Rifamycin S

Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation.
S4436新

Pleuromutilin

Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
S4491新

Cetylpyridinium chloride monohydrate

Cetylpyridinium chloride (CPC, Hexadecylpyridinium chloride) monohydrate is a broad-spectrum antimicrobial agent that possesses virucidal activity against susceptible and resistant strains of influenza virus by targeting and disrupting the viral envelope.
S9731新

PF-00835231

PF-00835231 is a 3CLpro (Mpro) inhibitor that may targets SARS-CoV-2 protease 3CLpro as a potential new treatment for COVID-19.
S3500新

Pentosan Polysulfate Sodium

Pentosan Polysulfate Sodium (PPS, Elmiron) is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also exhibits anti-HIV-1 activity.
S3499新

Monocaprylin

Monocaprylin (2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol, MC) exhibits an excellent antibacterial activity against Staphylococcus aureus and Escherichia coli.
S3496新

Lefamulin acetate (Xenleta)

Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.
S0861新

Laninamivir Octanoate

Laninamivir octanoate (CS-8958, R-118958, Inavir, LANI), a prodrug of Laninamivir (R-125489), is a long-acting neuraminidase (NA) inhibitor with superior anti-influenza virus activity.
S3356新

Phosphonoacetic acid

Phosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.
S3380新

Tecovirimat

Tecovirimat (Arestvyr, SIGA-246, ST-246, TPOXX) is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat is developed for the treatment of smallpox infection.
S4417新

Ceftaroline Fosamil

Ceftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).
S3226新

Dehydroabietic acid

Dehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways.
S3295新

Taxifolin 7-rhamnoside

Taxifolin 7-rhamnoside (TR, Taxifolin 7-O-rhamnoside, Taxifolin 7-O-α-L-rhamnoside), a flavonoid isolated from Hypericum japonicum, shows antibacterial activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
S3308新

Caftaric acid

Caftaric acid (CA, Caffeoyl tartaric acid) is a natural product that shows anti-oxidant and anti-inflammatory effects.
S3220新

Trigonelline

Trigonelline (Trigenolline) is a plant alkaloid and a major component of coffee and fenugreek with anti-degranulation, anti-diabetic, antioxidant, anti-inflammatory, and neuroprotective effects. Trigonelline inhibits FcεRI-mediated intracellular signaling pathways, such as phosphorylation of PLCγ1, PI3K, and Akt. Trigonelline (Trigenolline) also inhibits the microtubule formation in RBL-2H3 cells.
S3261新

Myrislignan

Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the expressions of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) dose-dependently in LPS-stimulated macrophage cells. Myrislignan inhibits the NF-κB signalling pathway activation.
S9669新

U18666A

U18666A (U18) is an inhibitor of intra-cellular cholesterol transport that inhibits dengue virus entry and replication.
S6867新

Glyceryl monocaprate (Monocaprin)

Monocaprin (Glyceryl caprate) is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.
S2764新

DTNB

DTNB (Ellman’s Reag, Ellmans Reagenz, 5,5′-Dithiobis(2-nitrobenzoic acid), 5,5′-Dithiobis-2-nitrobenzoesäure) is a non-fluorescent probe used to quantify the number or concentration of thiol groups in a sample. DTNB is also an allosteric inhibitor of dengue virus protease (NS2B-NS3pro) and Streptomyces proteases.
S6801新

AKOS B018304

AKOS B018304, an arylalkylidene derivative with polar substitution at para-position, is a potent inhibitor of chikungunya virus with low micro molar activity.
S6802新

Etosalamide

Etosalamide (Ethosalamide) is an anti-inflammatory drug with antipyretic and analgesics properties.
S8512新

Cenicriviroc (TAK-652)

Cenicriviroc (CVC, TAK-652, TBR-652) is a potent, orally active dual inhibitor of CC chemokine receptor 2 (CCR2) and CCR5. Cenicriviroc also inhibits HIV-1 and HIV-2 with potent anti-inflammatory and antiinfective activity.
S6845新

GRL0617

GRL0617 is a potent, selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLPro)/deubiquitinase with IC50 of 0.6 μM and Ki of 0.49 μM. GRL0617 inhibits SARS-CoV viral replication in Vero E6 cells with EC50 of 15 microM and has no associated cytotoxicity.
S6848新

3'-Fluoro-3'-deoxythymidine (Alovudine)

3'-Fluoro-3'-deoxythymidine (Alovudine, CL 184824, FddThd, FLT, MIV-310) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer.
S4307新

Auranofin

Auranofin (Ridaura, SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.

Oncotarget, 2018,
S0833新

EIDD-1931

EIDD-1931 (Beta-d-N4-hydroxycytidine, β-d-N4-hydroxycytidine, NHC) is an active metabolite of EIDD-2801, a promising COVID-19 inhibitor. EIDD-1931 (NHC) has broad spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and related zoonotic group 2b or 2c Bat-CoVs with average IC50 of 0.15 μM, as well as increased potency against a coronavirus bearing resistance mutations to the nucleoside analog inhibitor remdesivir.
S8969新

Molnupiravir (EIDD-2801)

Molnupiravir (EIDD-2801, MK-4482) is an orally bioavailable prodrug of the ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) with broad-spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and the causative agent of COVID-19.
S1230

Flavopiridol (L86-8275)

Flavopiridol (L86-8275, Alvocidib, NSC 649890, HMR-1275) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4, CDK6, and CDK9 with IC50 values in the 20-100 nM range. It is more selective for CDK1, 2, 4, 6, 9 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol induces autophagy and ER stress. Flavopiridol blocks HIV-1 replication. Phase 1/2.
Nature, 2021, 10.1038/s41586-021-03445-y
J Cell Biol, 2021, 220(7)e202008146
J Control Release, 2021, 333:246-257
S2003

Maraviroc (UK-427857)

Maraviroc (UK-427857) is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively. Maraviroc is used in the treatment of HIV infection.
Breast Cancer Res, 2021, 23(1):11
FASEB J, 2021, 35(4):e21402
Sci Adv, 2020, 22;6(21):eaaz8521
S2679

Flavopiridol (L86-8275) HCl

Flavopiridol HCl (L86-8275, NSC 649890, Alvocidib, HMR-1275, DSP-2033) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM in cell-free assays. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Flavopiridol HCl induces autophagy and ER stress. Flavopiridol HCl blocks HIV-1 replication. Phase 1/2.
Nature, 2021, 10.1038/s41586-021-03445-y
J Control Release, 2021, 333:246-257
PLoS Pathog, 2021, 17(4):e1009567
S2728

AG-1478 (Tyrphostin AG-1478)

AG-1478 (Tyrphostin AG-1478, NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. AG-1478 (Tyrphostin AG-1478) inhibits encephalomyocarditis virus (EMCV) and hepatitis c virus (HCV) by targeting phosphatidylinositol 4-kinase IIIα (PI4KA).
Theranostics, 2021, 11(3):996-1015
Oncogenesis, 2021, 10(3):25
Am J Transl Res, 2021, 13(2):708-718
S1209

Fluorouracil (5-Fluorouracil, 5-FU)

Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.
Theranostics, 2021, 11(9):4011-4029
Cell Rep, 2021, 34(10):108814
Cell Death Dis, 2021, 12(4):337
S1537

Vadimezan (ASA404)

Vadimezan (ASA404, NSC 640488, DMXAA) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. DMXAA (Vadimezan) is also a STING agonist with potential antineoplastic activity. DMXAA (Vadimezan) potently induces IFN-β but relatively low TNF-α expression in vitro. DMXAA (Vadimezan) has antiviral activity. Phase 3.
J Immunol, 2021, 206(9):2061-2074
Immunity, 2020, 7 pii: S1074-7613(20)30129-1
Sci Rep, 2020, 10(1):21360
S1117

Triciribine (NSC 154020)

Triciribine (NSC 154020, VD-0002, vqd-002, API-2, TCN) is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.
Aging (Albany NY), 2021, 13(5):7096-7119
J Cell Physiol, 2021, 10.1002/jcp.30343
Mol Cancer Ther, 2020, molcanther.0369.2020
S1228

Idarubicin HCl

Idarubicin HCl (4-demethoxydaunorubicin, NSC256439, 4-DMDR) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL in a cell-free assay. Idarubicin induces mTOR-dependent cytotoxic autophagy.
Int J Mol Sci, 2021, 22(3)1362
Cancers (Basel), 2021, 13(3)581
Cell, 2020, 182(3):685-712.e19
S7046

Brefeldin A

Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy.
Nat Biomed Eng, 2021, 10.1038/s41551-020-00675-9
Micromachines (Basel), 2021, 12(2)112
Cell Host Microbe, 2020, 11;27(3):476-485 e7
S1189

Aprepitant (MK-0869)

Aprepitant (MK-0869, L-754030) is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM. Aprepitant reduces levels of pro-inflammatory cytokines including G-CSF, IL-6, IL-8 and TNFα. Aprepitant inhibits HIV infection of human macrophages.
Nat Commun, 2020, 29;11(1):2673
Neuron, 2019, 103(3):432-444
Cell Syst, 2019, 8(2):97-108
S2713

Geldanamycin (NSC 122750)

Geldanamycin (NSC 122750) is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association. Geldanamycin attenuates virus infection-induced ALI (acute lung injury)/ARDS (acute respiratory distress syndrome) by reducing the host's inflammatory responses.
Anal Chem, 2020, 92(1):1363-1371
Anal Chem, 2020, 10.1021/acs.analchem.0c02756
Cell Biol Toxicol, 2020,
S1401

Tenofovir

Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections.
Antiviral Res, 2021, S0166-3542(21)00068-1
PLoS Pathog, 2020, 16(12):e1009024
Cells, 2020, 17;9(4) pii: E1003
S7015

Birinapant (TL32711)

Birinapant (TL32711) is a SMAC mimetic antagonist, mostly to cIAP1 with Kd of <1 nM in a cell-free assay, less potent to XIAP. Birinapant helps to induce apoptosis in latent HIV-1-infected cells. Phase 2.
Nat Commun, 2021, 12(1):2482
EMBO Mol Med, 2021, e13466
Cell Death Discov, 2021, 7(1):36
S1400

Tenofovir (GS 1278) Disoproxil Fumarate

Tenofovir Disoproxil Fumarate (GS-1278, Tenofovir DF) belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination.
J Virol, 2021, JVI.01777-20
ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00536
Antimicrob Agents Chemother, 2019, 64(1)
S1704

Emtricitabine (BW 1592)

Emtricitabine (BW1592, FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor. Intracellular half-life is 39 h.
J Virol, 2021, JVI.01777-20
ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00536
JCI Insight, 2019, 4(12)
S2597

Oseltamivir Phosphate

Oseltamivir Phosphate is a potent and selective inhibitor of the neuraminidase that is essential for replication of influenza A and B viruses, used to prevent influenza.
J Ethnopharmacol, 2021, S0378-8741(21)00290-7
J Cell Mol Med, 2018, 22(3):1826-1839
Infect Immun, 2015, 10.1128/IAI.03118-14
S3021

Rimonabant (SR141716)

Rimonabant (SR141716) is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Rimonabant is also a dual inhibitor of acyl CoA:cholesterol acyltransferases(ACAT) 1 and 2 and inhibits mycobacterial MmpL3.
Nat Commun, 2020, 11(1):5962
Sci Rep, 2020, 10(1):15556
Microbiol Immunol, 2020, 10.1111/1348-0421.12777
S8030

Plerixafor (AMD3100)

Plerixafor (AMD3100, JM 3100, SID791) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor inhibits human immunodeficiency virus (HIV) replication.
Diab Vasc Dis Res, 2021, 18(2):14791641211002473
Nat Commun, 2020, 11(1):5400
Cell Rep, 2020, 33(1):108221
S1896

Hydroxyurea (NSC-32065)

Hydroxyurea (NSC-32065, NCI-C04831, Hydroxycarbamide) is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase. Hydroxyurea activates apoptosis and autophagy. Hydroxyurea is used to treat HIV infection.
Cell Death Dis, 2021, 12(2):183
Carcinogenesis, 2021, bgab002
Cell Death Differ, 2021, 10.1038/s41418-020-00733-4
S1386

Nafamostat mesilate (FUT-175)

Nafamostat mesilate (FUT-175) is a synthetic serine protease inhibitor, used as an anticoagulant during hemodialysis. Nafamostat mesylate blocks activation of SARS-CoV-2 and is investigated as a new treatment option for COVID-19. Nafamostat Mesilate attenuates inflammation and apoptosis.
bioRxiv, 2021, 2021.03.31.437960
EMBO J, 2020, e2020106057
bioRxiv, 2020, 2020.10.02.324228
S1627

Nitazoxanide (NSC 697855)

Nitazoxanide (NSC 697855, NTZ) is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent(IC50 for canine influenza virus ranges from 0.17 to 0.21 μM). Nitazoxanide modulates autophagy and inhibits mTORC1 signaling.
Biomed J, 2020, S2319-4170(20)30066-4
bioRxiv, 2020, 2020/9/20.4.7.30734
Nat Chem Biol, 2018, 14(1):94-101
S1623

Acetylcysteine (N-acetylcysteine)

Acetylcysteine (N-acetyl-l-cysteine, NAC) is a ROS(reactive oxygen species) inhibitor that antagonizes the activity of proteasome inhibitors. It is also a tumor necrosis factor production inhibitor. Acetylcysteine(N-acetyl-l-cysteine) suppresses TNF-induced NF-κB activation through inhibition of IκB kinases. Acetylcysteine(N-acetyl-l-cysteine) induces apoptosis via the mitochondria-dependent pathway. Acetylcysteine(N-acetyl-l-cysteine) inhibits ferroptosis and virus replication.Solutions of Acetylcysteine are best fresh-prepared.
Redox Biol, 2021, S2213-2317(21)00076-8
J Exp Clin Cancer Res, 2021, 40(1):121
Mol Oncol, 2021, 10.1002/1878-0261.12936
S1384

Mizoribine

Mizoribine (Bredinin, NSC 289637) is an imidazole nucleoside and an immunosuppressant that inhibits HCV RNA replication with IC50 of ~ 100 μM for anti-HCV activity. Mizoribine is a selective inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH) and guanosine monophosphate synthetase. Mizoribine also inhibits SARS-CoV.
JCI Insight, 2020, 9;5(7):e135071
Cancer Cell, 2017, 32(5):624-638
S8047

Dynasore

Dynasore is a cell-permeable, reversible non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2, with IC50 of 15 μM in a cell-free assay, also inhibits the mitochondrial dynamin Drp1, with no effect against other small GTPase. Dynasore suppresses mTORC1 activity and induces autophagy. Dynasore inhibits the entry of several viruses, including herpes simplex virus (HSV).
Theranostics, 2021, 11(5):2364-2380
Front Microbiol, 2021, 12:636307
Theranostics, 2021, 11(5):2364-2380
S1848

Curcumin

Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM）and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.
Phytomedicine, 2021, 85:153547
Adv Biol Regul, 2021, S2212-4926(20)30091-9
Mol Cell, 2020, 80(3):525-540.e9
S4157

Chloroquine diphosphate

Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs).
Theranostics, 2021, 11(2):700-714
Autophagy, 2021, 1-19
Cell Death Dis, 2021, 12(1):65
S2310

Honokiol (NSC 293100)

Honokiol (NSC 293100) is the active principle of magnolia extract that inhibits Akt-phosphorylation and promotes ERK1/2 phosphorylation. Honokiol causes G0/G1 phase arrest, induces apoptosis, and autophagy via the ROS/ERK1/2 signaling pathway. Honokiol inhibits hepatitis C virus (HCV) infection. Phase 3.
Front Cell Dev Biol, 2021, 9:619475
Pathogens, 2021, 10(2)244
Cell Death Dis, 2021, 12(2):173
S2239

Tubacin

Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM in a cell-free assay, approximately 350-fold selectivity over HDAC1. Tubacin reduces the replication of the Japanese Encephalitis Virus via the decrease of viral RNA synthesis.
Cancers (Basel), 2020, 12(11)E3172
FASEB J, 2020, 10.1096/fj.202001508R
Int J Mol Sci, 2020, 22(1)E142
S1351

Ivermectin (MK-933)

Ivermectin (MK-933, IVM) is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug. Ivermectin (MK-933, IVM) is a specific positive allosteric effector of P2X4 and α7 nicotinic acetylcholine receptors (nAChRs). Ivermectin has potent antiviral activity towards both HIV-1 and dengue virus. Ivermectin induces autophagy through the AKT/mTOR signaling pathway and mitophagy.
Nat Cell Biol, 2020,
Blood Cancer J, 2020, 10(6):72
Cancers (Basel), 2020, 12(9)E2668
S2527

Methacycline HCl

Methacycline HCl (Rondomycin) is a tetracycline antibiotic, and also an inhibitor of epithelial–mesenchymal transition (EMT) with IC50 of roughly 5 μM, used to treat various infections.
Cancer Cell Int, 2020, 19;20:58
Hum Cell, 2020, 10.1007/s13577-020-00425-8
Hum Cell, 2020, 10.1007/s13577-020-00420-z
S1677

Chloramphenicol

Chloramphenicol (Chloromycetin) is a bacteriostatic by inhibiting protein synthesis.
Cell Rep, 2021, 34(3):108631
Oncotarget, 2018, 9(40):26086-26095
S2716

Peramivir Trihydrate

Peramivir Trihydrate (BCX-1812, RWJ-270201, S-021812) is a trihydrate of the anti-infection agent peramivir which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
Emerg Microbes Infec, 2014, 3, e78
Emerg Microbes Infect, 2014, 3(11):e78
S2457

Clindamycin HCl

Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
Proc Natl Acad Sci U S A, 2016, 113(50):14408-14413
S1611

Cefoperazone

Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.
S3007

Zanamivir

Zanamivir (GG167) is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.
Emerg Microbes Infec, 2014, 3, e78
Emerg Microbes Infect, 2014, 3(11):e78
S2908

Hygromycin B

Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.
Autophagy, 2021, 1-17
PLoS Pathog, 2021, 17(4):e1009530
Cell Res, 2020,
S1997

Liranaftate

Liranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities.
S1791

Bacitracin Zinc

Bacitracin is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.

S2572

Streptomycin sulfate

Streptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor.
Biosci Rep, 2021, BSR20200842
Nutrients, 2020, 12(6):E1901
NPJ Precis Oncol, 2020, 4:21
S1618

Sulfameter

Sulfameter is a long-acting sulfonamide antibacterial.
S1685

Sulfanilamide

Sulfanilamide (Sulphanilamide) is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.
S8279

Shikonin (C.I. 75535)

Shikonin (C.I. 75535, Anchusin, Anchusa acid, Alkanna Red, Isoarnebin 4, NSC 252844), a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. Shikonin exerts an anti-inflammatory effect by inhibiting tumor necrosis factor-α (TNF-α) and prevents activation of nuclear factor-κB (NF-κB) pathway via proteasome inhibition.
Rheumatology (Oxford), 2020, keaa473
Am J Cancer Res, 2020, 10(11):3784-3800
Antiviral Res, 2020, 182:104924
S8750

NGI-1 (ML414)

NGI-1 (ML414) is an aminobenzamide-sulfonamide compound that targets both oligosaccharyltransferase (OST) isoforms and therefore may exhibit antiviral activity against flaviviruses.
S5144

Neferine

Neferine ((R)-1,2-Dimethoxyaporphine), a natural component of Nelumbo nucifera, has antitumor efficiency. Neferine induces apoptosis in renal cancer cells. Neferine prevents autophagy through activation of Akt/mTOR pathway and Nrf2 in muscle cells. Neferine strongly inhibits NF-κB activation. Neferine possesses a number of therapeutic effects such as anti-diabetic, anti-aging, anti-microbial, anti-thrombotic, anti-arrhythmic, anti-inflammatory and even anti-HIV.
Oncol Rep, 2020, 44(3):1116-1126
S0515

PLpro inhibitor 

PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor with IC50 of 2.6 μM.
S2830

Clindamycin

Clindamycin inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
S7311

Q-VD-Oph

Q-VD-Oph (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a potent pan-caspase inhibitor with IC50 ranged from 25 to 400 nM for caspases 1,3,8, and 9. Q-VD-OPh can inhibits HIV infection.
Haematologica, 2021, 10.3324/haematol.2020.259531
Autophagy, 2021, 1-18
Int J Mol Sci, 2021, 22(8)3811
S5554

Lanatoside C

Lanatoside C is a cardiac glycoside with antiviral and anti-tumor activity. Lanatoside C induces G2/M cell cycle arrest and induces autophagy and apoptosis via attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR signaling pathways.
S0285

Bay 41-4109 racemate

BAY 41-4109 racemate (BAY41-4109 Racemic) is a mixture of R-isomer of BAY 41-4109 and S-isomer of BAY 41-4109. BAY 41-4109 an antiviral compound that inhibits human hepatitis B virus (HBV) with IC50 of 53 nM.
Nat Commun, 2021, 12(1):2114
S0038

AB-423

AB-423, a member of the sulfamoylbenzamide (SBA) class of hepatitis B virus (HBV) capsid inhibitors, shows potent inhibition of HBV replication with EC50 of 0.08 μM - 0.27 μM and EC90 of 0.33 μM - 1.32 μM in cells. Phase 1.
S0289

KIN1148

KIN1148 is an agonist of interferon regulatory factor 3 (IRF3) that induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters. KIN1148 is an influenza vaccine adjuvant that enhances flu vaccine efficacy.
S5268

Solithromycin

Solithromycin (CEM-101, OP-1068), belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
S7975

Favipiravir (T-705)

Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.

mBio, 2021, 12(1)e02754-20
Antiviral Res, 2021, S0166-3542(21)00068-1
Viruses, 2020, 22;12(3) pii: E351
S4941

Farnesol

Farnesol is a natural sesquiterpene alcohol that is potent in treating antimetabolic disorders, anti-inflammation, showing antioxidant, anticancer, and antibiotic effects.
S7550

Erythromycin Cyclocarbonate

Erythromycin Cyclocarbonate, derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.

S4599

Benzyl benzoate

Benzyl benzoate (Ascabiol, Novoscabin, Scabitox, Benzoic acid benzyl ester) is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
S7784

Fumagillin

Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.

S0076

ABX464

ABX464 (SPL-464) is a novel anti-HIV molecule that inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) from 5 different donors with IC50 ranging between 0.1 μM and 0.5 μM.
S1553

Delafloxacin (ABT-492)

Delafloxacin (ABT-492, RX-3341, WQ-3034) is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens.
S4861

Oxindole

Oxindole (2-indolone, 2-Oxindole, Indolin-2-one) is an aromatic heterocyclic organic compound which causes sedation, muscle weakness, hypotension, and coma when dosed in excess.
S4946

2,3-Dihydroxybenzoic acid

2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties.
S6676

Ebselen

Ebselen (DR 3305, SPI-1005, PZ-51, CCG-39161) is a small-molecule capsid inhibitor of HIV-1 Replication with IC50 of 46.1 nM in TR-FRET assay.
Viruses, 2021, 13(2)173
Antiviral Res, 2020, 182:104924
S4647

Cefmenoxime hydrochloride

Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.
S5499

Amantadine

Amantadine (1-Adamantanamine, 1-Adamantylamine, 1-Aminoadamantane) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.
S4602

Acetohydroxamic acid

Acetohydroxamic acid (N-Hydroxyacetamide, Methylhydroxamic acid, Acetic acid|oxime, Lithostat) is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.
S8133

Resiquimod (R-848)

Resiquimod (R-848, S28463) is an immune response modifier that acts as a potent TLR 7/TLR 8 agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. Resiquimod reduces hepatitis C virus (HCV) infection. Phase 2.
Pharmaceutics, 2021, 13(3)365
bioRxiv, 2021, 2021.03.31.437792
Vaccines (Basel), 2020, 15;8(2):E186
S8588

ACSS2 inhibitor

ACSS2 inhibitor is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2). ACSS2 inhibitor also inhibits the respiratory syncytial virus (RSV).
JCI Insight, 2021, 6(7)144156
S6549

PBTZ169

PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1.
Cell Death Dis, 2019, 10(4):319
S9303

Saikosaponin B2

Saikosaponin B2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.
Phytomedicine, 2019, 67:153163
S0349

Inarigivir soproxil

Inarigivir soproxil (GS 9992, SB 9200) is an oral agonist of innate immunity that is believed to act via the activation of the RIG-I and NOD2 pathways. Inarigivir soproxil has broad-spectrum antiviral activity against RNA viruses with EC50 of 2.2 μM and 1.0 μM for HCV 1a and HCV 1b.
S9018

Luteoloside

Luteoloside (Cynaroside, Luteolin 7-β-D-Glucopyranoside) is a member of the flavonoids family that exhibits several bioactivities including anti-microbial and anti-cancer activities. It is an inhibitor of 3C Protease of Enterovirus 71 with an IC50 value of 0.36 mM.
S5345

Nerolidol

Nerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.
Int Immunopharmacol, 2020, 80:106118
S7775

Emricasan (IDN-6556)

Emricasan (IDN-6556, PF 03491390, PF-03491390) is a potent irreversible pan-caspase inhibitor. Emricasan is an inhibitor of Zika virus infection.
Cell Death Differ, 2021, 10.1038/s41418-020-00685-9
Cell Death Dis, 2021, 12(2):140
Biochim Biophys Acta Mol Cell Biol Lipids, 2021, 1866(5):158902
S7273

SC75741

SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM. SC75741 efficiently blocks influenza virus propagation.
Biomed Res Int, 2021, 2021:8621464
Int J Cancer, 2020, 10.1002/ijc.33371
Front Cell Dev Biol, 2020, 8:606123
S8068

Chaetocin

Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR).
Stem Cells Int, 2021, 2021:8888416
Nat Commun, 2020, 11(1):4709
Front Endocrinol (Lausanne), 2020, 11:323
S9063

Harringtonine

Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.
S4430

Hydroxychloroquine Sulfate (NSC 4375)

Hydroxychloroquine Sulfate (NSC 4375, HCQ) is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.

Autophagy, 2021, 1-14
Cell Rep, 2021, 35(1):108940
Cell Death Dis, 2021, 12(4):347
S9064

Trilobatin

Trilobatin (P-Phlorizin), a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect.
S4303

9-Aminoacridine

9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.
S5704

Myclobutanil

Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S0147

KKL-10

KKL-10 is an inhibitor of ribosome rescue that exhibits exceptional broad-spectrum antimicrobial activity against bacteria.
S4983

Sorbic acid

Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
S9070

Isoxanthohumol

Isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
S4198

Aminothiazole

Aminothiazole can be used as a thyroid inhibitor and it has antibacterial activity.
J Electroanal Chem (Lausanne), 2020, 878:114733
S5927

Proguanil

Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
S3710

Fosfomycin calcium

Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
S5166

Benzoyleneurea

Benzoyleneurea (2,4-Dihydroxyquinazoline, Quinazolinedione, Quinazoline-2,4-diol) scaffold is used in the synthesis of novel protein geranylgeranyltransferase-I inhibitors.
S8932

Remdesivir (GS-5734)

Remdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.
Nat Commun, 2021, 12(1):668
Cell Rep, 2021, 35(1):108940
mBio, 2021, 12(1)e02754-20
S6771

MAC-545496

MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. MAC-545496 shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model.
S4104

Diminazene Aceturate

Diminazene is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent.
Am J Physiol Lung Cell Mol Physiol, 2020, 10.1152/ajplung.00025.2020
S4105

Closantel Sodium

Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
S4106

Closantel

Closantel (R-31520) is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
S3711

Carbasalate Calcium

Carbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor.
S6689

Merimepodib

Merimepodib (Merimempodib, MMPD, VI-21,497, VX-497) is a potent, specific, and reversible inosine monophosphate dehydrogenase(IMPDH) inhibitor with antiviral activity against hepatitis C virus (HCV) and a variety of DNA and RNA viruses in vitro.Merimepodib is an immunosuppressive agent.
S4701

2-Deoxy-D-glucose (2-DG)

2-Deoxy-D-glucose (2-DG, 2-deoxyglucose, NSC 15193, 2-Deoxy-D-arabino-hexose, D-Arabino-2-deoxyhexose), an analog of glucose, is a glycolytic inhibitor with antiviral activity. 2-Deoxy-D-glucose induces apoptosis and inhibits Herpes Simplex Virus type-1 (HSV-1) receptor expression.
Cancer Cell, 2020, 38(5):672-684.e6
Cancer Cell, 2020, 13;37(4):599-617 e7
Elife, 2020, 9e56749
S9341

3,4-Dimethoxycinnamic acid

3,4-Dimethoxycinnamic acid (Caffeic acid dimethyl ether) is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S0433

Nucleozin

Nucleozin is an antivirus agent that targets influenza A nucleoprotein (NP). Nucleozin triggers the aggregation of NP and inhibits its nuclear accumulation.
S0195

Walrycin B

Walrycin B is an antibacterial compound and a potent inhibitor of WalR targeting the WalR response regulator.
S0436

Pleconaril

Pleconaril (APO-P001, Picovir, VP 63843, WIN 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication with IC50 of < 0.050 μM.
S4515

Ademetionine disulfate tosylate

Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.
S3028

Geneticin (G418 Sulfate)

Geneticin (G418 Sulfate), an aminoglycoside antibiotic, is an elongation inhibitor of 80 S ribosomes that blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
Sci Adv, 2021, 7(7)eabd2645
Autophagy, 2021, 1-17
Redox Biol, 2021, 41:101904
S7417

Puromycin (CL13900) 2HCl

Puromycin 2HCl (CL13900) is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.

Nucleic Acids Res, 2021, gkab034
Theranostics, 2021, 11(6):2966-2986
Autophagy, 2021, 1-17
S4780

7-Methoxy-4-methylcoumarin

7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label.
S4783

Benzyl isothiocyanate

Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities.
Biomolecules, 2019, 9(12)
S7867

Oleuropein

Oleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2.
J Med Virol, 2019, 91(8):1440-1447
S0467

Emodepside

Emodepside (QHT06, BAY 44-4400, PF 1022-221), a semisynthetic derivative of PF1022A, is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Emodepside activates Ca-dependent SLO-1-like K channels.
S0470

RSV604

RSV604 (A-60444), a novel benzodiazepine, is an inhibitor of respiratory syncytial virus (RSV) with EC50 of 0.86 μM. RSV604 has significant potential for the effective treatment of RSV disease. Phase 2.
S4549

Antimonyl potassium tartrate trihydrate

Antimonyl potassium tartrate trihydrate (Tartar emetic) is a powerful emetic, also used in the treatment of schistosomiasis and leishmaniasis.
S6814

GS-441524

GS-441524, a molecular precursor to a pharmacologically active nucleoside triphosphate molecule, is a potent inhibitor of feline infectious peritonitis virus (FIPV) with EC50 of 0.78 μM.
Front Pharmacol, 2020, 11:606097
S5183

PD 169316

PD 169316 is a potent, selective and cell-permeable p38 MAP kinase inhibitor with IC50 of 89 nM. PD169316 abrogates signaling initiated by both TGFbeta and Activin A. PD169316 shows antiviral activity against Enterovirus71.
S7419

Blasticidin S HCl

Blasticidin S HCl is a nucleoside antibiotic isolated from Stretomyces girseochromogenes, and acts as a DNA and protein synthesis inhibitor, used to select transfected cells carrying bsr or BSD resistance genes.

Theranostics, 2021, 11(6):2966-2986