Anti-infection
阻害剤の選択性比較
カタログ番号 | 製品カタログ | 溶解度(25°C) | ||
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水 | DMSO | アルコール | ||
S5001 | Tofacitinib (CP-690550) Citrate | <1 mg/mL | 100 mg/mL | '<1 mg/mL |
S4157 | Chloroquine diphosphate | 100 mg/mL | <1 mg/mL | <1 mg/mL |
E0206 | Ginkgetin | -1 mg/mL | 50 mg/mL | -1 mg/mL |
S2572 | Streptomycin sulfate | 89 mg/mL | <1 mg/mL | <1 mg/mL |
S8279 | Shikonin (C.I. 75535) | <1 mg/mL | 57 mg/mL | 23 mg/mL |
S3226 | Dehydroabietic acid | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S4945 | Ethacridine lactate | 69 mg/mL | 69 mg/mL | ''20 mg/mL |
S5184 | Dexamethasone palmitate | <1 mg/mL | 100 mg/mL | ''100 mg/mL |
S3308 | Caftaric acid | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S1553 | Delafloxacin (ABT-492) | <1 mg/mL | 88 mg/mL | '<1 mg/mL |
S4946 | 2,3-Dihydroxybenzoic acid | -1 mg/mL | 30 mg/mL | -1 mg/mL |
S8068 | Chaetocin | <1 mg/mL | 100 mg/mL | <1 mg/mL |
S4430 | Hydroxychloroquine Sulfate (NSC 4375) | 67 mg/mL | <1 mg/mL | ''<1 mg/mL |
S4303 | 9-Aminoacridine | <1 mg/mL | 38 mg/mL | '38 mg/mL |
S5927 | Proguanil | <1 mg/mL | 51 mg/mL | '51 mg/mL |
S4417 | Ceftaroline Fosamil | <1 mg/mL | 73 mg/mL | ''''<1 mg/mL |
S6771 | MAC-545496 | ˂1 mg/mL | 84 mg/mL | ˂1 mg/mL |
S3711 | Carbasalate Calcium | 91 mg/mL | 11 mg/mL | <1 mg/mL |
S9341 | 3,4-Dimethoxycinnamic acid | -1 mg/mL | 42 mg/mL | -1 mg/mL |
S4515 | Ademetionine disulfate tosylate | 79 mg/mL | 79 mg/mL | <1 mg/mL |
S2430 | Azodicarbonamide | <1 mg/mL | 23 mg/mL | <1 mg/mL |
S6802 | Etosalamide | 6 mg/mL | 42 mg/mL | '42 mg/mL |
S7867 | Oleuropein | 100 mg/mL | 100 mg/mL | 100 mg/mL |
S3261 | Myrislignan | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S4549 | Antimonyl potassium tartrate trihydrate | 100 mg/mL | <1 mg/mL | <1 mg/mL |
S7465 | FTI 277 HCl | 17 mg/mL | 96 mg/mL | '14 mg/mL |
S1958 | Sulbactam | 47 mg/mL | 47 mg/mL | 47 mg/mL |
S3269 | Acetylcorynoline | -1 mg/mL | 40 mg/mL | -1 mg/mL |
S3270 | Genipin 1-O-beta-D-gentiobioside | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S3279 | Polyphyllin B (Formosanin C) | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S1282 | Artemisinin | <1 mg/mL | 57 mg/mL | 24 mg/mL |
S2264 | Artemether | <1 mg/mL | 60 mg/mL | 60 mg/mL |
S2479 | Lincomycin HCl | 89 mg/mL | 89 mg/mL | <1 mg/mL |
S1644 | Nitrofural | <1 mg/mL | 40 mg/mL | <1 mg/mL |
S4237 | Primaquine Diphosphate | 91 mg/mL | 91 mg/mL | <1 mg/mL |
S2469 | Fleroxacin | <1 mg/mL | <1 mg/mL | <1 mg/mL |
S3116 | Sulfathiazole | <1 mg/mL | 51 mg/mL | <1 mg/mL |
S2511 | Sulfadoxine | <1 mg/mL | 62 mg/mL | <1 mg/mL |
S3067 | Chlorhexidine 2HCl | <1 mg/mL | 100 mg/mL | <1 mg/mL |
S4147 | Azithromycin Dihydrate | 10 mg/mL | 100 mg/mL | 100 mg/mL |
S4191 | Betamipron | <1 mg/mL | 39 mg/mL | 39 mg/mL |
S2537 | Secnidazole | 37 mg/mL | 37 mg/mL | 37 mg/mL |
S4195 | Broxyquinoline | <1 mg/mL | 17 mg/mL | <1 mg/mL |
S4196 | Ethacridine lactate monohydrate | 5 mg/mL | 72 mg/mL | <1 mg/mL |
S2612 | Ribitol | 30 mg/mL | 30 mg/mL | <1 mg/mL |
S4726 | Lauric Acid | 20 mg/mL | 40 mg/mL | 40 mg/mL |
S3288 | Absinthin | -1 mg/mL | 10 mg/mL | -1 mg/mL |
S3941 | Pinocembrin | <1 mg/mL | 51 mg/mL | 51 mg/mL |
S4579 | Resorcinol | 22 mg/mL | 22 mg/mL | 22 mg/mL |
S9564 | p-Hydroxy-cinnamic Acid | <1 mg/mL | 33 mg/mL | 33 mg/mL |
S6288 | Chlorhexidine diacetate | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S5366 | Fipronil | -1 mg/mL | 87 mg/mL | -1 mg/mL |
S4420 | Mefloquine HCl | <1 mg/mL | 82 mg/mL | 82 mg/mL |
S4142 | Clopidol | <1 mg/mL | 1 mg/mL | <1 mg/mL |
S4592 | Captisol (SBE-β-CD) | 100 mg/mL | <1 mg/mL | <1 mg/mL |
S5700 | Phthalylsulfathiazole | -1 mg/mL | 80 mg/mL | '-1 mg/mL |
S4041 | Olsalazine Sodium | 41 mg/mL | 4 mg/mL | <1 mg/mL |
S4250 | Sulfamethoxypyridazine | <1 mg/mL | 56 mg/mL | '<1 mg/mL |
S5397 | Chlorhexidine | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S2271 | Berberine chloride (NSC 646666) | <1 mg/mL | 40 mg/mL | <1 mg/mL |
S2282 | Cinchonidine | <1 mg/mL | 59 mg/mL | 59 mg/mL |
S5475 | Novaluron | -1 mg/mL | 99 mg/mL | '-1 mg/mL |
S3218 | Amiloxate | ' mg/mL | ||
S5963 | Sulfathiazole sodium | 55 mg/mL | 55 mg/mL | ''<1 mg/mL |
S5967 | Berberine chloride hydrate | 39 mg/mL | 78 mg/mL | '<1 mg/mL |
S4172 | Cetylpyridinium Chloride | 68 mg/mL | 68 mg/mL | 68 mg/mL |
S6243 | Ethyl pyruvate | ' mg/mL | ||
S3695 | Cystamine dihydrochloride | 45 mg/mL | 14 mg/mL | '2 mg/mL |
S4175 | Sulfaguanidine | <1 mg/mL | 43 mg/mL | <1 mg/mL |
S2395 | Rheochrysidin | <1 mg/mL | 1 mg/mL | <1 mg/mL |
S3787 | Picroside I | -1 mg/mL | 98 mg/mL | -1 mg/mL |
S9016 | Dipsacoside B | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S5908 | Garenoxacin | <1 mg/mL | 2 mg/mL | <1 mg/mL |
S3649 | Ceftazidime | 100 mg/mL | 4 mg/mL | <1 mg/mL |
S4062 | Ronidazole | <1 mg/mL | 40 mg/mL | <1 mg/mL |
S4971 | Buparvaquone | <1 mg/mL | 65 mg/mL | '4 mg/mL |
S6761 | Dalfopristin | <1 mg/mL | 100 mg/mL | ''''100 mg/mL |
S4192 | Chlorquinaldol | <1 mg/mL | 46 mg/mL | 6 mg/mL |
S5292 | Diazolidinyl urea | -1 mg/mL | 55 mg/mL | -1 mg/mL |
S3210 | 3'-Hydroxy-4'-methoxyacetophenone | <1 mg/mL | 33 mg/mL | 33 mg/mL |
S5961 | Prednisolone disodium phosphate | 97 mg/mL | 97 mg/mL | '''<1 mg/mL |
S5887 | Khellin | <1 mg/mL | 26 mg/mL | 7 mg/mL |
S4081 | Sulfacetamide Sodium | 51 mg/mL | 19 mg/mL | <1 mg/mL |
S4759 | p-Coumaric Acid | <1 mg/mL | 32 mg/mL | '32 mg/mL |
S7411 | Ascomycin (FK520) | <1 mg/mL | 100 mg/mL | 100 mg/mL |
S0146 | Broxaldine | <1 mg/mL | 30 mg/mL | <1 mg/mL |
S6019 | 2-Phenylphenol | -1 mg/mL | 34 mg/mL | -1 mg/mL |
S9387 | Maackiain | -1 mg/mL | 56 mg/mL | -1 mg/mL |
S3364 | 3-Hydroxyphenylacetic acid | 30 mg/mL | 30 mg/mL | '''30 mg/mL |
S9084 | Rhoifolin | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S3801 | Sodium Houttuyfonate | <1 mg/mL | 2 mg/mL | <1 mg/mL |
S2613 | Clorsulon | <1 mg/mL | 76 mg/mL | 7 mg/mL |
S6442 | Chlorphenesin | 10 mg/mL | 41 mg/mL | 41 mg/mL |
S9342 | 1,4-Naphthoquinone | -1 mg/mL | 32 mg/mL | -1 mg/mL |
S2564 | Cloxacillin Sodium | 55 mg/mL | 55 mg/mL | 25 mg/mL |
S9112 | Kaempferitrin | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S5096 | SulfadiMethoxine sodium | -1 mg/mL | 66 mg/mL | '-1 mg/mL |
S9113 | Ononin | -1 mg/mL | 86 mg/mL | -1 mg/mL |
S5099 | 4-Aminophenylarsonic acid | -1 mg/mL | 43 mg/mL | -1 mg/mL |
S6459 | Nifurtimox | <1 mg/mL | 57 mg/mL | <1 mg/mL |
S4232 | Nithiamide | <1 mg/mL | 37 mg/mL | <1 mg/mL |
S3618 | Acetylspiramycin (ASPM) | <1 mg/mL | 100 mg/mL | '15 mg/mL |
P1201 | LL37 (Human cathelicidin) | 50 mg/mL | -1 mg/mL | -1 mg/mL |
S4236 | Proflavine Hemisulfate | 22 mg/mL | <1 mg/mL | <1 mg/mL |
S3746 | Lumefantrine | <1 mg/mL | 13 mg/mL | <1 mg/mL |
S5212 | Imidazolidinyl Urea | -1 mg/mL | 77 mg/mL | '-1 mg/mL |
S5210 | Sulfamethazine Sodium Salt | -1 mg/mL | 60 mg/mL | -1 mg/mL |
S0443 | Desciclovir | 25 mg/mL | 42 mg/mL | '3 mg/mL |
S4678 | Povidone iodine | 28 mg/mL | 28 mg/mL | '28 mg/mL |
S9131 | Punicalagin | -1 mg/mL | 100 mg/mL | -1 mg/mL |
S3139 | Methenamine | <1 mg/mL | 28 mg/mL | 9 mg/mL |
S5405 | Propylparaben | <1 mg/mL | 36 mg/mL | 36 mg/mL |
S4242 | Cetrimonium Bromide (CTAB) | 100 mg/mL | 5 mg/mL | 100 mg/mL |
S5214 | Imidocarb dipropionate | -1 mg/mL | 39 mg/mL | -1 mg/mL |
S6461 | Permethrin | <1 mg/mL | 78 mg/mL | 19 mg/mL |
S3978 | 5-Phenyl-2,4-pentadienoic acid | -1 mg/mL | 6 mg/mL | '-1 mg/mL |
S3220 | Trigonelline | -1 mg/mL | 50 mg/mL | -1 mg/mL |
S5390 | N-(Hytroxymethy)micotinamide | -1 mg/mL | 30 mg/mL | '-1 mg/mL |
S5355 | Piperaquine phosphate | 2 mg/mL | <1 mg/mL | -1 mg/mL |
S9560 | Anisodamine Hydrobromide | -1 mg/mL | 77 mg/mL | -1 mg/mL |
S5005 | Cefotiam hydrochloride | -1 mg/mL | 100 mg/mL | '-1 mg/mL |
S1962 | Sulphadimethoxine | <1 mg/mL | 62 mg/mL | <1 mg/mL |
S4555 | Carsalam | <1 mg/mL | 32 mg/mL | 2 mg/mL |
S7896 | Sodium Tauroursodeoxycholate (TUDC) | 100 mg/mL | 100 mg/mL | 71 mg/mL |
S9185 | Nitidine Chloride | -1 mg/mL | 11 mg/mL | -1 mg/mL |
Anti-infection製品
製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
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S5001 |
Tofacitinib (CP-690550) CitrateTofacitinib citrate (CP-690550, Tasocitinib) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity. |
![]() ![]() CP-690550 reduced the severity of ischemic damage. (A) CP-690550 (10 μM) suppressed IL-17 production by cdT cells and activated memory T cells. cdT cells and CD4+ CD44+ memory T cells isolated from C5BL6J mice through flow cytometry were stimulated for 24 h with plate-bound monoclonal antibodies to CD3 (2 ng/ml) and CD28 (1 ng/ml) in the presence or absence of IL-23 (25 ng/ml). IL-17A production and IL-17A expression level were measured by quantitative RT-PCR (a) and ELISA (b). (B) CBF reduction after brain ischemia. (C) Time-dependent changes in neurological score. *p < 0.05. (D) Infarct volume as visualized through TTC staining on day 3 in CP-690550 (CP)- and vehicle-treated mice.
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S4157 |
Chloroquine diphosphateChloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs). |
![]() ![]() NCI-H929 EV and miR-137 OE cells were treated with ATM activator Chloroquine Phosphate (CQ), specific ATM inhibitor KU-55933, and ATR inhibitor AZ20 for 12 hr. Immunoblotting showed the expression of p-ATM, p-Chk2, p-BRCA1, p-ATR and p-Chk1. |
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E0206新 |
GinkgetinGinkgetin is a biflavone from Ginkgo biloba leaves with anti-cancer, anti-inflammatory, anti-microbial, anti-adipogenic, and neuroprotective activities. |
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S2572 |
Streptomycin sulfateStreptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor. |
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S8279 |
Shikonin (C.I. 75535)Shikonin (C.I. 75535, Anchusin, Anchusa acid, Alkanna Red, Isoarnebin 4, NSC 252844), a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. Shikonin exerts an anti-inflammatory effect by inhibiting tumor necrosis factor-α (TNF-α) and prevents activation of nuclear factor-κB (NF-κB) pathway via proteasome inhibition. |
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S3226 |
Dehydroabietic acidDehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways. |
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S4945 |
Ethacridine lactateEthacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. |
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S5184 |
Dexamethasone palmitateDexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity. |
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S3308 |
Caftaric acidCaftaric acid (CA, Caffeoyl tartaric acid) is a natural product that shows anti-oxidant and anti-inflammatory effects. |
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S1553 |
Delafloxacin (ABT-492)Delafloxacin (ABT-492, RX-3341, WQ-3034) is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens. |
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S4946 |
2,3-Dihydroxybenzoic acid2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties. |
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S8068 |
ChaetocinChaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR). |
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S4430 |
Hydroxychloroquine Sulfate (NSC 4375)Hydroxychloroquine Sulfate (NSC 4375, HCQ) is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. |
![]() ![]() C, SA-beta gal staining results of A549-LKB1 cells treated by trametinib (30 nmol/L), radiotherapy (2 Gy), and HCQ (50 μmol/L). Cells were treated by HCQ and/or trametinib 4 hours prior to radiotherapy. Drugs were washed out 24 hours after radiotherapy. Cells were incubated for additional 48 hours before staining. D, Clonogenic survival assay of A549-LKB1 cells treated with trametinib (30 nmol/L) and HCQ (50 μmol/L).
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S4303 |
9-Aminoacridine9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix. |
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S5927 |
ProguanilProguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication. |
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S4417 |
Ceftaroline FosamilCeftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). |
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S6771 |
MAC-545496MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. MAC-545496 shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model. |
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S3711 |
Carbasalate CalciumCarbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor. |
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S9341 |
3,4-Dimethoxycinnamic acid3,4-Dimethoxycinnamic acid (Caffeic acid dimethyl ether) is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM. |
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S4515 |
Ademetionine disulfate tosylateAdemetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. |
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S2430 |
AzodicarbonamideAzodicarbonamide is the first known nucleocapsid inhibitor that inhibits HIV-1 and a broad range of retroviruses by targeting the nucleocapsid CCHC domains. Azodicarbonamide inhibits the HIV-1RF-induced cytopathicity of CEM-SS cells with an EC50 of 38 µM in a standard cell-based antiviral assay . |
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S6802 |
EtosalamideEtosalamide (Ethosalamide) is an anti-inflammatory drug with antipyretic and analgesics properties. |
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S7867 |
OleuropeinOleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2. |
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S3261 |
MyrislignanMyrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the expressions of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) dose-dependently in LPS-stimulated macrophage cells. Myrislignan inhibits the NF-κB signalling pathway activation. |
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S4549 |
Antimonyl potassium tartrate trihydrateAntimonyl potassium tartrate trihydrate (Tartar emetic) is a powerful emetic, also used in the treatment of schistosomiasis and leishmaniasis. |
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S7465 |
FTI 277 HClFTI 277 HCl is the methyl ester of FTI 277, which is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia. |
![]() ![]() (A) HCT 116 cells were treated with Tram (0, 30, or 60 nM), and then treated with 10 μM FTI-277/4 μM GGTI-298 or vehicle control for 48 hr. CCK8 assays were performed to assess cell proliferation and growth. The data from a representative example of three independent experiments are presented as the mean±SD. (B) SW480 and MDA-MB-231 cells were treated with Tram (0, 80, 160 nM), and then treated with 10 μM FTI-277/4 μM GGTI-298 or vehicle control for 48 hr. CCK8 assays were performed to assess cell proliferation and growth. The data from a representative example of three independent experiments are presented as the mean±SD.
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S1958 |
SulbactamSulbactam is a beta-lactamase inhibitor with an average IC50 of 0.8 μM. |
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S3269 |
AcetylcorynolineAcetylcorynoline, a major alkaloid component derived from Corydalis bungeana which is a traditional Chinese medical herb, shows anti-inflammatory properties. Acetylcorynoline may decrease egl-1 expression to suppress apoptosis pathways and increase rpn5 expression to enhance the activity of proteasomes. |
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S3270 |
Genipin 1-O-beta-D-gentiobiosideGenipin 1-O-beta-D-gentiobioside (GG, Genipin 1-β-D-gentiobioside, Genipin 1-gentiobioside, Genipin 1-β-gentiobioside, Genipin gentiobioside) is a bioactive iridoid glycoside isolated from Gardenia jasminoides Ellis (Zhizi in Chinese) that exhibits hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities. |
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S3279 |
Polyphyllin B (Formosanin C)Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis. |
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S1282 |
ArtemisininArtemisinin (Qinghaosu, Artemisinine) is a sesquiterpene endoperoxide which is a potent antimalarial agent. |
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S2264 |
ArtemetherArtemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria. |
![]() ![]() Schistosomicidal effects of PZQ, ART(Artemether) and OXA on 14-day schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development. |
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S2479 |
Lincomycin HClLincomycin hydrochloride (Lincocin, NSC 70731) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis. |
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S1644 |
NitrofuralNitrofural (Nitrofurazone) is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg) |
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S4237 |
Primaquine DiphosphatePrimaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria. |
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S2469 |
FleroxacinFleroxacin (Ro 23-6240, AM-833) is a new broad-spectrum fluoroquinolone. |
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S3116 |
SulfathiazoleSulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug. |
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S2511 |
SulfadoxineSulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax. |
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S3067 |
Chlorhexidine 2HClChlorhexidine hydrochloride (NSC-185) is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms. |
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S4147 |
Azithromycin DihydrateAzithromycin Dihydrate is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin. |
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S4191 |
BetamipronBetamipron (CS-443) is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity. |
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S2537 |
SecnidazoleSecnidazole (Flagentyl, PM 185184, RP 14539) is a nitroimidazole anti-infective. |
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S4195 |
BroxyquinolineBroxyquinoline is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes. |
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S4196 |
Ethacridine lactate monohydrateEthacridine lactate monohydrate is an aromatic organic compound based on acridine used as an antiseptic agent. |
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S2612 |
RibitolRibitol (Adonitol) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis. |
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S4726 |
Lauric AcidLauric Acid (dodecanoic acid, N-Dodecanoic acid, Dodecylic acid) is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil. |
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S3288 |
AbsinthinAbsinthin (Absynthine) is a naturally produced triterpene lactone from Artemisia absinthium with anti-inflammatory properties. Absinthin significantly enhances the expression of matrix metalloproteinase-8 (MMP-8) and is a possible treatment candidate for Acute lung injury (ALI). |
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S3941 |
PinocembrinPinocembrin (Dihydrochrysin, Galangin flavanone, 5,7-Dihydroxyflavanone) is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry. Its vast range of pharmacological activities has been well researched including antimicrobial, anti-inflammatory, antioxidant, and anticancer activities. |
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S4573 |
m-Tolyl acetatem-Tolyl acetate is a pharmaceutical intermediate and antiseptic. |
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S4579 |
ResorcinolResorcinol is a chemical compound that serves as an antiseptic,an disinfectant, and a chemical intermediate for the production of many other pharmaceuticals. |
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S9564 |
p-Hydroxy-cinnamic Acidp-Hydroxy-cinnamic Acid has in vitro antimalarial activity and in vivo anti-osteoporotic properties. |
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S6288 |
Chlorhexidine diacetateChlorhexidine diacetate (Hibitane diacetate) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. |
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S5366 |
FipronilFipronil (Fluocyanobenpyrazole, Termidor) is a recalcitrant phenylpyrazole-based pesticide used for flea/tick treatment and termite control that is distributed in urban aquatic environments via stormwater and contributes to stream toxicity. |
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S9094 |
PogostonePogostone is one of the secondary metabolites from Pogostemon cablin (Blanco) Benth. (Lamiaceae), serving as the effective component of the antimicrobial activity. |
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S4420 |
Mefloquine HClMefloquine HCl is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug. |
![]() ![]() BALB/c mice, orally infected with E. multilocularis eggs, were treated by either mefloquine (100 mg/kg twice per week, n = 9), ABZ (200 mg/kg, 5 times per week, n = 8) or control-treated (placebo, n = 9). After 12 weeks of treatment, parasite lesion numbers in the liver were assessed microscopically (A).
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S4142 |
ClopidolClopidol (WR 61112) is an antiprotozoal agent. |
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S4592 |
Captisol (SBE-β-CD)Captisol (SBE-β-CD, Sulfobutylether-β-Cyclodextrin) is a novel, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs. |
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S5700 |
PhthalylsulfathiazolePhthalylsulfathiazole (Sulfathalidine) is a broad-spectrum antimicrobial that can treat different types of infections including intestinal. |
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S4041 |
Olsalazine SodiumOlsalazine Sodium is an anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond. |
![]() ![]() Values represent the average scores for each group ± S.E. (N = 10 per group). The differences between individual experimental groups and 17 days DSS only group were statistically significant (p < 0.05) for all groups.
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S6136 |
(±)-α-Bisabololα-bisabolol is a small, plant-derived, oily sesquiterpene alcohol with some anti-inflammatory and even anti-microbial properties. |
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S5757 |
IsoeugenolIsoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity. |
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S4250 |
SulfamethoxypyridazineSulfamethoxypyridazine (CL 13494) is a long-acting sulfonamide for treatment of Dermatitis herpetiformis. |
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S5397 |
ChlorhexidineChlorhexidine is a disinfectant and topical anti-infective agent that is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts. |
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S6173 |
AmylmetacresolAmylmetacresol is an antiseptic used to treat infections of the mouth and throat. |
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S6185 |
Arachidonic acidArachidonic acid (Arachidonate) is an unsaturated, essential fatty acid found in animal and human fat as well as in the liver, brain, and glandular organs. It is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. |
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S2271 |
Berberine chloride (NSC 646666)Berberine chloride (NSC 646666, Natural Yellow 18) is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator. |
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S2282 |
CinchonidineCinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry. |
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S5475 |
NovaluronNovaluron (Rimon) belongs to the class of insecticides called insect growth regulators with pesticide properties. |
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S3218 |
AmiloxateAmiloxate (Amiloxiate, Isoamyl Methoxycinnamate, Isopentyl 4-methoxycinnamate, Isoamyl 4-methoxycinnamate, Isoamyl p-methoxycinnamate, Isopentyl p-methoxycinnamate) is EMA-approved chemical UV-filter used in cosmetics. Amiloxate is a cinnamic acid derivative with anti-inflammatory activity. |
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S5963 |
Sulfathiazole sodiumSulfathiazole sodium, an antimicrobial agent, is an organosulfur compound that has been used as a short-acting sulfa drug. |
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S5967 |
Berberine chloride hydrateBerberine (Natural Yellow 18) chloride hydrate is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator. |
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S4172 |
Cetylpyridinium ChlorideCetylpyridinium chloride is a cationic quaternary ammonium compound used as oropharyngeal antiseptic. |
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S6243 |
Ethyl pyruvateEthyl pyruvate (CTI-01) is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions. |
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S3695 |
Cystamine dihydrochlorideCystamine dihydrochloride (Decarboxycystine, 2-Aminoethyl disulfide, 2,2'-Dithiobisethanamine) acts as an anti-infective agent, which is used in the treatment of urinary tract infections and also as a radiation-protective agent that interferes with sulfhydryl enzymes. |
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S4175 |
SulfaguanidineSulfaguanidine is a sulfonamide used as an anti-infective agent. |
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S2395 |
RheochrysidinRheochrysidin (Physcione) is an anthraquinone from roots of Rheum officinale Baill. |
![]() ![]() AmpC β-lactamase and MDH inhibition dose-response curves in the absence (black circles) and presence (red triangles) of DTT for (C and D) physcion. |
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S3787 |
Picroside IPicroside I (6'-Cinnamoylcatalpol), an iridoid glycoside, is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B. |
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S9016 |
Dipsacoside BDipsacoside B, extracted from the flowerbuds of Lonicera confusa DC, shows strong antimicrobial activity. |
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S5908 |
GarenoxacinGarenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes. |
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S3649 |
CeftazidimeCeftazidime is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa. |
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S4062 |
RonidazoleRonidazole is an antiprotozoal agent. |
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S4971 |
BuparvaquoneBuparvaquone (Butalex) is a second-generation hydroxynaphthoquinone related to parvaquone, with novel features that make it a promising compound for the therapy and prophylaxis of all forms of theileriosis. |
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S6761 |
DalfopristinDalfopristin (RP54476) is a semi-synthetic analogue of ostreogyrcin A. Quinupristin/dalfopristin (Q/D) is a parental streptogramin with a spectrum of activity that includes Gram-positive pathogens, including those resistant to other classes of antimicrobial compounds. |
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S4192 |
ChlorquinaldolChlorquinaldol is an antimicrobial agent used for local antisepsy. |
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S5292 |
Diazolidinyl ureaDiazolidinyl urea (Germall II) is an antimicrobial preservative used in cosmetics. |
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S3210 |
3'-Hydroxy-4'-methoxyacetophenone3'-Hydroxy-4'-methoxyacetophenone (Acetoisovanillone, Isoacetovanillone, Diosmin EP Impurity A) is an active P. spinosa extract with anti-inflammatory potential. |
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S5961 |
Prednisolone disodium phosphatePrednisolone disodium phosphate (Hydeltrasol, Prednisolone 21-phosphate disodium) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties that exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells. |
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S5887 |
KhellinKhellin (Methafrone, Visammin, Ammivisnagen, Khellinorm, Medekellin, Viscardan, Kalangin), a compound isolated from the seeds of Ammi Visnaga Lam (Umbelliferae), is used to treat a variety of maladies. |
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S4081 |
Sulfacetamide SodiumSulfacetamide Sodium is an anti-biotic. |
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S4759 |
p-Coumaric Acidp-Coumaric acid (4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant, anti-inflammatory, and antimicrobial activity. |
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S7411 |
Ascomycin (FK520)Ascomycin (FK520, FR 900520, Immunomycin), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3. |
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S0146 |
BroxaldineBroxaldine (Brobenzoxaldine, AL307) is an antiprotozoal drug and can be used in leprosy. |
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S6019 |
2-Phenylphenol2-Phenylphenol, found in lemon, is an antifungal agent and preservative used in food seasonings. |
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S9387 |
MaackiainMaackiain (Demethylpterocarpin) is a pterocarpan that is widely distributed in leguminous plants. It has anticancer and antimicrobial effects. |
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S3364 |
3-Hydroxyphenylacetic acid3-Hydroxyphenylacetic acid (3-HPAA) is a phenolic acid mostly found in olive oil wastewater and an intestinal metabolite of the dietary flavonoid quercetin. 3-Hydroxyphenylacetic acid exhibits antimicrobial properties. |
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S9084 |
RhoifolinRhoifolin (Rhoifoloside, Apigenin 7-O-neohesperidoside, Apigenin-7-O-rhamnoglucoside), a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects. |
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S3801 |
Sodium HouttuyfonateSodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis. |
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S2613 |
ClorsulonClorsulon (MK-401) is used in the treatment of Fasciola hepatica infections in calves and sheep. |
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S6442 |
ChlorphenesinChlorphenesin is a synthetic preservative used in skin care as a cosmetic biocide. |
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S9342 |
1,4-Naphthoquinone1,4-Naphthoquinone (α-Naphthoquinone, para-naphthoquinone, P-Naphthoquinone), found in diesel exhaust particles and it is an active metabolite of naphthalene, is a fumigant insecticide. |
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S2564 |
Cloxacillin SodiumCloxacillin Sodium is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin. |
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S9112 |
KaempferitrinKaempferitrin (Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside), isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities. |
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S5096 |
SulfadiMethoxine sodiumSulfadimethoxine (Sulfadimethoxydiazine) is a long-lasting sulfonamide antimicrobial agent used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections. |
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S9113 |
OnoninOnonin (Formononetin glucoside, Formononetin 7-O-glucoside) is an isoflavone glycoside with anti-inflammtory effects. |
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S5099 |
4-Aminophenylarsonic acid4-Aminophenylarsonic acid (Arsanilic Acid) is an organoarsenic compound with activity as an anti-infective agent. |
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S6459 |
NifurtimoxNifurtimox (BAY-2502) is an antiprotozoal agent. |
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S4232 |
NithiamideNithiamide (CL 5279) is a non-5-nitroimidazole drugs. |
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S3618 |
Acetylspiramycin (ASPM)Acetylspiramycin (ASPM, Spiramycin II, Foromacidin B) is a macrolide antimicrobial agent. |
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P1201 |
LL37 (Human cathelicidin)LL37 (Human cathelicidin, Ropocamptide) is a cathelicidin-related antimicrobial peptide with potent chemotactic and immunomodulatory properties. |
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S4236 |
Proflavine HemisulfateProflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands. |
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S3746 |
LumefantrineLumefantrine (benflumetol) is an antimalarial agent used to treat acute uncomplicated malaria. |
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S5212 |
Imidazolidinyl UreaImidazolidinyl Urea (Imidurea) is an antimicrobial agent used as preservative in cosmetics. |
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S5210 |
Sulfamethazine Sodium SaltSulfamethazine (Sulfadimethyldiazine) is a sulfanilamide anti-infective agent used in the lifestock industry. |
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S0443 |
DesciclovirDesciclovir (DCV, 6-Deoxyacyclovir, BW A515U) is a prodrug of the antiherpetic agent acyclovir (ACV) that converted into ACV by xanthine oxidase in humans. |
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S4678 |
Povidone iodinePovidone iodine (Betadine, PVP iodine, PVP-I, Isodine) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It is used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. |
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S9131 |
PunicalaginPunicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects. |
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S3139 |
MethenamineMethenamine is an antibiotic used for the treatment of urinary tract infection. |
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S5405 |
PropylparabenPropylparaben (Propyl 4-hydroxybenzoate, Propyl p-hydroxybenzoate, nipasol), a natural substance found in many plants and some insects, is an antimicrobial, preservative and flavouring agent. |
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S4242 |
Cetrimonium Bromide (CTAB)Cetrimonium Bromide (CTAB) is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts. |
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S5214 |
Imidocarb dipropionateImidocarb is an antiprotozoal agent, used as dipropionate in the treatment of babesiosis and ehrlichiosis. |
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S6461 |
PermethrinPermethrin is a synthetic Type I pyrethroidal neurotoxic pesticide that has been responsible for accidental animal deaths. |
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S3978 |
5-Phenyl-2,4-pentadienoic acid5-Phenyl-2,4-pentadienoic acid (5-Phenylpenta-2,4-dienoic acid) is used as Synthetic building block, anti-malarial agent. |
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S3220 |
TrigonellineTrigonelline (Trigenolline) is a plant alkaloid and a major component of coffee and fenugreek with anti-degranulation, anti-diabetic, antioxidant, anti-inflammatory, and neuroprotective effects. Trigonelline inhibits FcεRI-mediated intracellular signaling pathways, such as phosphorylation of PLCγ1, PI3K, and Akt. Trigonelline (Trigenolline) also inhibits the microtubule formation in RBL-2H3 cells. |
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S5390 |
N-(Hytroxymethy)micotinamideN-(Hydroxymethyl)nicotinamide (Nikomethamide, Bilamid, N-hydroxymethylnicotinamide) is an antimicrobial agent. |
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S5355 |
Piperaquine phosphatePiperaquine phosphate is an orally active bisquinolone antimalarial drug. |
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S9560 |
Anisodamine HydrobromideAnisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs). |
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S5005 |
Cefotiam hydrochlorideCefotiam hydrochloride (Halospor, Pansporin, Pansporine) is the hydrochloride salt form of cefotiam and has a broad spectrum of activity against both gram-positive and gram-negative microorganisms. |
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S1962 |
SulphadimethoxineSulphadimethoxine is a non-reducing glucuronide. |
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S4555 |
CarsalamCarsalam (Carbonylsalicylamide) is a nonsteroidal anti-inflammatory drug. |
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S7896 |
Sodium Tauroursodeoxycholate (TUDC)Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis. |
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S4521 |
DEETDEET (N,N-Diethyl-meta-toluamide, diethyltoluamide) is a commen active ingredient insect repellent. |
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S9185 |
Nitidine ChlorideNitidine Chloride, a benzophenanthridine alkaloid found in species of the genus Zanthoxylum, has an anti-malarial activity. |
製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
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S5001 |
Tofacitinib (CP-690550) CitrateTofacitinib citrate (CP-690550, Tasocitinib) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity. |
![]() ![]() CP-690550 reduced the severity of ischemic damage. (A) CP-690550 (10 μM) suppressed IL-17 production by cdT cells and activated memory T cells. cdT cells and CD4+ CD44+ memory T cells isolated from C5BL6J mice through flow cytometry were stimulated for 24 h with plate-bound monoclonal antibodies to CD3 (2 ng/ml) and CD28 (1 ng/ml) in the presence or absence of IL-23 (25 ng/ml). IL-17A production and IL-17A expression level were measured by quantitative RT-PCR (a) and ELISA (b). (B) CBF reduction after brain ischemia. (C) Time-dependent changes in neurological score. *p < 0.05. (D) Infarct volume as visualized through TTC staining on day 3 in CP-690550 (CP)- and vehicle-treated mice.
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S4157 |
Chloroquine diphosphateChloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs). |
![]() ![]() NCI-H929 EV and miR-137 OE cells were treated with ATM activator Chloroquine Phosphate (CQ), specific ATM inhibitor KU-55933, and ATR inhibitor AZ20 for 12 hr. Immunoblotting showed the expression of p-ATM, p-Chk2, p-BRCA1, p-ATR and p-Chk1. |
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E0206新 |
GinkgetinGinkgetin is a biflavone from Ginkgo biloba leaves with anti-cancer, anti-inflammatory, anti-microbial, anti-adipogenic, and neuroprotective activities. |
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S2572 |
Streptomycin sulfateStreptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor. |
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S8279 |
Shikonin (C.I. 75535)Shikonin (C.I. 75535, Anchusin, Anchusa acid, Alkanna Red, Isoarnebin 4, NSC 252844), a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. Shikonin exerts an anti-inflammatory effect by inhibiting tumor necrosis factor-α (TNF-α) and prevents activation of nuclear factor-κB (NF-κB) pathway via proteasome inhibition. |
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S3226 |
Dehydroabietic acidDehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways. |
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S4945 |
Ethacridine lactateEthacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. |
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S5184 |
Dexamethasone palmitateDexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity. |
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S3308 |
Caftaric acidCaftaric acid (CA, Caffeoyl tartaric acid) is a natural product that shows anti-oxidant and anti-inflammatory effects. |
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S1553 |
Delafloxacin (ABT-492)Delafloxacin (ABT-492, RX-3341, WQ-3034) is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens. |
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S4946 |
2,3-Dihydroxybenzoic acid2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties. |
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S8068 |
ChaetocinChaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR). |
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S4430 |
Hydroxychloroquine Sulfate (NSC 4375)Hydroxychloroquine Sulfate (NSC 4375, HCQ) is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. |
![]() ![]() C, SA-beta gal staining results of A549-LKB1 cells treated by trametinib (30 nmol/L), radiotherapy (2 Gy), and HCQ (50 μmol/L). Cells were treated by HCQ and/or trametinib 4 hours prior to radiotherapy. Drugs were washed out 24 hours after radiotherapy. Cells were incubated for additional 48 hours before staining. D, Clonogenic survival assay of A549-LKB1 cells treated with trametinib (30 nmol/L) and HCQ (50 μmol/L).
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S4303 |
9-Aminoacridine9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix. |
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S5927 |
ProguanilProguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication. |
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S4417 |
Ceftaroline FosamilCeftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). |
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S6771 |
MAC-545496MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. MAC-545496 shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model. |
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S3711 |
Carbasalate CalciumCarbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor. |
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S9341 |
3,4-Dimethoxycinnamic acid3,4-Dimethoxycinnamic acid (Caffeic acid dimethyl ether) is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM. |
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S4515 |
Ademetionine disulfate tosylateAdemetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. |
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S2430 |
AzodicarbonamideAzodicarbonamide is the first known nucleocapsid inhibitor that inhibits HIV-1 and a broad range of retroviruses by targeting the nucleocapsid CCHC domains. Azodicarbonamide inhibits the HIV-1RF-induced cytopathicity of CEM-SS cells with an EC50 of 38 µM in a standard cell-based antiviral assay . |
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S6802 |
EtosalamideEtosalamide (Ethosalamide) is an anti-inflammatory drug with antipyretic and analgesics properties. |
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S7867 |
OleuropeinOleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2. |
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S3261 |
MyrislignanMyrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the expressions of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) dose-dependently in LPS-stimulated macrophage cells. Myrislignan inhibits the NF-κB signalling pathway activation. |
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S4549 |
Antimonyl potassium tartrate trihydrateAntimonyl potassium tartrate trihydrate (Tartar emetic) is a powerful emetic, also used in the treatment of schistosomiasis and leishmaniasis. |
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S7465 |
FTI 277 HClFTI 277 HCl is the methyl ester of FTI 277, which is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia. |
![]() ![]() (A) HCT 116 cells were treated with Tram (0, 30, or 60 nM), and then treated with 10 μM FTI-277/4 μM GGTI-298 or vehicle control for 48 hr. CCK8 assays were performed to assess cell proliferation and growth. The data from a representative example of three independent experiments are presented as the mean±SD. (B) SW480 and MDA-MB-231 cells were treated with Tram (0, 80, 160 nM), and then treated with 10 μM FTI-277/4 μM GGTI-298 or vehicle control for 48 hr. CCK8 assays were performed to assess cell proliferation and growth. The data from a representative example of three independent experiments are presented as the mean±SD.
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S1958 |
SulbactamSulbactam is a beta-lactamase inhibitor with an average IC50 of 0.8 μM. |
製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
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S3269 |
AcetylcorynolineAcetylcorynoline, a major alkaloid component derived from Corydalis bungeana which is a traditional Chinese medical herb, shows anti-inflammatory properties. Acetylcorynoline may decrease egl-1 expression to suppress apoptosis pathways and increase rpn5 expression to enhance the activity of proteasomes. |
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S3270 |
Genipin 1-O-beta-D-gentiobiosideGenipin 1-O-beta-D-gentiobioside (GG, Genipin 1-β-D-gentiobioside, Genipin 1-gentiobioside, Genipin 1-β-gentiobioside, Genipin gentiobioside) is a bioactive iridoid glycoside isolated from Gardenia jasminoides Ellis (Zhizi in Chinese) that exhibits hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities. |
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S3279 |
Polyphyllin B (Formosanin C)Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis. |
2021, 22(1):550 |
製品コード | 製品説明 | 文献中Selleckの製品使用例 | お客様のフィードバック |
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S1282 |
ArtemisininArtemisinin (Qinghaosu, Artemisinine) is a sesquiterpene endoperoxide which is a potent antimalarial agent. |
2021, 12:634368 2021, 95:107541 2020, 29:104810 |
|
S2264 |
ArtemetherArtemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria. |
2022, 10.1007/s13577-022-00671-y 2021, 11(1):14571 2021, 34(6):1911-1918 |
![]() ![]() Schistosomicidal effects of PZQ, ART(Artemether) and OXA on 14-day schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development. |
S2479 |
Lincomycin HClLincomycin hydrochloride (Lincocin, NSC 70731) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis. |
2022, 10.1007/s13577-022-00671-y 2021, 10.1007/s13577-021-00639-4 2021, 34(6):1911-1918 |
|
S1644 |
NitrofuralNitrofural (Nitrofurazone) is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg) |
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S4237 |
Primaquine DiphosphatePrimaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria. |
2021, 12:695009 2019, 8(2):97-108 |
|
S2469 |
FleroxacinFleroxacin (Ro 23-6240, AM-833) is a new broad-spectrum fluoroquinolone. |
||
S3116 |
SulfathiazoleSulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug. |
||
S2511 |
SulfadoxineSulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax. |
||
S3067 |
Chlorhexidine 2HClChlorhexidine hydrochloride (NSC-185) is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms. |
2020, 20(1):275 |
|
S4147 |
Azithromycin DihydrateAzithromycin Dihydrate is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin. |
2022, 10.1002/jcb.30213 2020, 16(12):e1008489 2020, 2020.10.02.324228 |
|
S4191 |
BetamipronBetamipron (CS-443) is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity. |
||
S2537 |
SecnidazoleSecnidazole (Flagentyl, PM 185184, RP 14539) is a nitroimidazole anti-infective. |
||
S4195 |
BroxyquinolineBroxyquinoline is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes. |
||
S4196 |
Ethacridine lactate monohydrateEthacridine lactate monohydrate is an aromatic organic compound based on acridine used as an antiseptic agent. |
2014, 35(12):2822-30 |
|
S2612 |
RibitolRibitol (Adonitol) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis. |
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S4726 |
Lauric AcidLauric Acid (dodecanoic acid, N-Dodecanoic acid, Dodecylic acid) is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil. |
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S3288 |
AbsinthinAbsinthin (Absynthine) is a naturally produced triterpene lactone from Artemisia absinthium with anti-inflammatory properties. Absinthin significantly enhances the expression of matrix metalloproteinase-8 (MMP-8) and is a possible treatment candidate for Acute lung injury (ALI). |
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S3941 |
PinocembrinPinocembrin (Dihydrochrysin, Galangin flavanone, 5,7-Dihydroxyflavanone) is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry. Its vast range of pharmacological activities has been well researched including antimicrobial, anti-inflammatory, antioxidant, and anticancer activities. |
2020, 17(1):337 |
|
S4573 |
m-Tolyl acetatem-Tolyl acetate is a pharmaceutical intermediate and antiseptic. |
||
S4579 |
ResorcinolResorcinol is a chemical compound that serves as an antiseptic,an disinfectant, and a chemical intermediate for the production of many other pharmaceuticals. |
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S9564 |
p-Hydroxy-cinnamic Acidp-Hydroxy-cinnamic Acid has in vitro antimalarial activity and in vivo anti-osteoporotic properties. |
||
S6288 |
Chlorhexidine diacetateChlorhexidine diacetate (Hibitane diacetate) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. |
2020, 20(1):275 |
|
S5366 |
FipronilFipronil (Fluocyanobenpyrazole, Termidor) is a recalcitrant phenylpyrazole-based pesticide used for flea/tick treatment and termite control that is distributed in urban aquatic environments via stormwater and contributes to stream toxicity. |
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S9094 |
PogostonePogostone is one of the secondary metabolites from Pogostemon cablin (Blanco) Benth. (Lamiaceae), serving as the effective component of the antimicrobial activity. |
2021, 278:114250 |
|
S4420 |
Mefloquine HClMefloquine HCl is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug. |
2021, 23(1)40 2020, 2020/9/20.4.7.30734 2018, 8(2):331-340 |
![]() ![]() BALB/c mice, orally infected with E. multilocularis eggs, were treated by either mefloquine (100 mg/kg twice per week, n = 9), ABZ (200 mg/kg, 5 times per week, n = 8) or control-treated (placebo, n = 9). After 12 weeks of treatment, parasite lesion numbers in the liver were assessed microscopically (A).
|
S4142 |
ClopidolClopidol (WR 61112) is an antiprotozoal agent. |
||
S4592 |
Captisol (SBE-β-CD)Captisol (SBE-β-CD, Sulfobutylether-β-Cyclodextrin) is a novel, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs. |
2022, S1550-4131(22)00083-3 2022, 34(1):171-183.e6 2021, S0092-8674(21)00690-5 |
|
S5700 |
PhthalylsulfathiazolePhthalylsulfathiazole (Sulfathalidine) is a broad-spectrum antimicrobial that can treat different types of infections including intestinal. |
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S4041 |
Olsalazine SodiumOlsalazine Sodium is an anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond. |
2017, 8(1):228-237 |
![]() ![]() Values represent the average scores for each group ± S.E. (N = 10 per group). The differences between individual experimental groups and 17 days DSS only group were statistically significant (p < 0.05) for all groups.
|
S6136 |
(±)-α-Bisabololα-bisabolol is a small, plant-derived, oily sesquiterpene alcohol with some anti-inflammatory and even anti-microbial properties. |
||
S5757 |
IsoeugenolIsoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity. |
||
S4250 |
SulfamethoxypyridazineSulfamethoxypyridazine (CL 13494) is a long-acting sulfonamide for treatment of Dermatitis herpetiformis. |
||
S5397 |
ChlorhexidineChlorhexidine is a disinfectant and topical anti-infective agent that is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts. |
2021, 10.1111/jcmm.16673 2020, 20(1):275 |
|
S6173 |
AmylmetacresolAmylmetacresol is an antiseptic used to treat infections of the mouth and throat. |
||
S6185 |
Arachidonic acidArachidonic acid (Arachidonate) is an unsaturated, essential fatty acid found in animal and human fat as well as in the liver, brain, and glandular organs. It is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. |
2022, 10(1):20 |
|
S2271 |
Berberine chloride (NSC 646666)Berberine chloride (NSC 646666, Natural Yellow 18) is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator. |
2021, 12:632201 2021, 26(5)1210 2021, 10(3)250 |
|
S2282 |
CinchonidineCinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry. |
2019, 91(8):1440-1447 |
|
S5475 |
NovaluronNovaluron (Rimon) belongs to the class of insecticides called insect growth regulators with pesticide properties. |
||
S3218 |
AmiloxateAmiloxate (Amiloxiate, Isoamyl Methoxycinnamate, Isopentyl 4-methoxycinnamate, Isoamyl 4-methoxycinnamate, Isoamyl p-methoxycinnamate, Isopentyl p-methoxycinnamate) is EMA-approved chemical UV-filter used in cosmetics. Amiloxate is a cinnamic acid derivative with anti-inflammatory activity. |
||
S5963 |
Sulfathiazole sodiumSulfathiazole sodium, an antimicrobial agent, is an organosulfur compound that has been used as a short-acting sulfa drug. |
||
S5967 |
Berberine chloride hydrateBerberine (Natural Yellow 18) chloride hydrate is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator. |
2021, 12:632201 |
|
S4172 |
Cetylpyridinium ChlorideCetylpyridinium chloride is a cationic quaternary ammonium compound used as oropharyngeal antiseptic. |
||
S6243 |
Ethyl pyruvateEthyl pyruvate (CTI-01) is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions. |
||
S3695 |
Cystamine dihydrochlorideCystamine dihydrochloride (Decarboxycystine, 2-Aminoethyl disulfide, 2,2'-Dithiobisethanamine) acts as an anti-infective agent, which is used in the treatment of urinary tract infections and also as a radiation-protective agent that interferes with sulfhydryl enzymes. |
||
S4175 |
SulfaguanidineSulfaguanidine is a sulfonamide used as an anti-infective agent. |
||
S2395 |
RheochrysidinRheochrysidin (Physcione) is an anthraquinone from roots of Rheum officinale Baill. |
2015, 10.1021/cb5009487 |
![]() ![]() AmpC β-lactamase and MDH inhibition dose-response curves in the absence (black circles) and presence (red triangles) of DTT for (C and D) physcion. |
S3787 |
Picroside IPicroside I (6'-Cinnamoylcatalpol), an iridoid glycoside, is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B. |
||
S9016 |
Dipsacoside BDipsacoside B, extracted from the flowerbuds of Lonicera confusa DC, shows strong antimicrobial activity. |
||
S5908 |
GarenoxacinGarenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes. |
||
S3649 |
CeftazidimeCeftazidime is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa. |
||
S4062 |
RonidazoleRonidazole is an antiprotozoal agent. |
||
S4971 |
BuparvaquoneBuparvaquone (Butalex) is a second-generation hydroxynaphthoquinone related to parvaquone, with novel features that make it a promising compound for the therapy and prophylaxis of all forms of theileriosis. |
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S6761 |
DalfopristinDalfopristin (RP54476) is a semi-synthetic analogue of ostreogyrcin A. Quinupristin/dalfopristin (Q/D) is a parental streptogramin with a spectrum of activity that includes Gram-positive pathogens, including those resistant to other classes of antimicrobial compounds. |
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S4192 |
ChlorquinaldolChlorquinaldol is an antimicrobial agent used for local antisepsy. |
||
S5292 |
Diazolidinyl ureaDiazolidinyl urea (Germall II) is an antimicrobial preservative used in cosmetics. |
||
S3210 |
3'-Hydroxy-4'-methoxyacetophenone3'-Hydroxy-4'-methoxyacetophenone (Acetoisovanillone, Isoacetovanillone, Diosmin EP Impurity A) is an active P. spinosa extract with anti-inflammatory potential. |
||
S5961 |
Prednisolone disodium phosphatePrednisolone disodium phosphate (Hydeltrasol, Prednisolone 21-phosphate disodium) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties that exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells. |
2021, 18(1):154-162 2021, 10.5152/eurjrheum.2021.20054 |
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S5887 |
KhellinKhellin (Methafrone, Visammin, Ammivisnagen, Khellinorm, Medekellin, Viscardan, Kalangin), a compound isolated from the seeds of Ammi Visnaga Lam (Umbelliferae), is used to treat a variety of maladies. |
||
S4081 |
Sulfacetamide SodiumSulfacetamide Sodium is an anti-biotic. |
2020, 4;10(5):1585-1597 |
|
S4759 |
p-Coumaric Acidp-Coumaric acid (4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant, anti-inflammatory, and antimicrobial activity. |
2021, 21(5):503 2015, 26(11):1379-84 |
|
S7411 |
Ascomycin (FK520)Ascomycin (FK520, FR 900520, Immunomycin), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3. |
2020, 30(4):325-335 2019, 34(6):648-661 |
|
S0146 |
BroxaldineBroxaldine (Brobenzoxaldine, AL307) is an antiprotozoal drug and can be used in leprosy. |
||
S6019 |
2-Phenylphenol2-Phenylphenol, found in lemon, is an antifungal agent and preservative used in food seasonings. |
||
S9387 |
MaackiainMaackiain (Demethylpterocarpin) is a pterocarpan that is widely distributed in leguminous plants. It has anticancer and antimicrobial effects. |
||
S3364 |
3-Hydroxyphenylacetic acid3-Hydroxyphenylacetic acid (3-HPAA) is a phenolic acid mostly found in olive oil wastewater and an intestinal metabolite of the dietary flavonoid quercetin. 3-Hydroxyphenylacetic acid exhibits antimicrobial properties. |
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S9084 |
RhoifolinRhoifolin (Rhoifoloside, Apigenin 7-O-neohesperidoside, Apigenin-7-O-rhamnoglucoside), a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects. |
||
S3801 |
Sodium HouttuyfonateSodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis. |
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S2613 |
ClorsulonClorsulon (MK-401) is used in the treatment of Fasciola hepatica infections in calves and sheep. |
2022, 10.1007/s13577-022-00671-y 2021, 34(6):1911-1918 2021, 10.1007/s13577-021-00579-z |
|
S6442 |
ChlorphenesinChlorphenesin is a synthetic preservative used in skin care as a cosmetic biocide. |
||
S9342 |
1,4-Naphthoquinone1,4-Naphthoquinone (α-Naphthoquinone, para-naphthoquinone, P-Naphthoquinone), found in diesel exhaust particles and it is an active metabolite of naphthalene, is a fumigant insecticide. |
||
S2564 |
Cloxacillin SodiumCloxacillin Sodium is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin. |
||
S9112 |
KaempferitrinKaempferitrin (Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside), isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities. |
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S5096 |
SulfadiMethoxine sodiumSulfadimethoxine (Sulfadimethoxydiazine) is a long-lasting sulfonamide antimicrobial agent used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections. |
2018, 9(6):646 |
|
S9113 |
OnoninOnonin (Formononetin glucoside, Formononetin 7-O-glucoside) is an isoflavone glycoside with anti-inflammtory effects. |
||
S5099 |
4-Aminophenylarsonic acid4-Aminophenylarsonic acid (Arsanilic Acid) is an organoarsenic compound with activity as an anti-infective agent. |
||
S6459 |
NifurtimoxNifurtimox (BAY-2502) is an antiprotozoal agent. |
||
S4232 |
NithiamideNithiamide (CL 5279) is a non-5-nitroimidazole drugs. |
||
S3618 |
Acetylspiramycin (ASPM)Acetylspiramycin (ASPM, Spiramycin II, Foromacidin B) is a macrolide antimicrobial agent. |
||
P1201 |
LL37 (Human cathelicidin)LL37 (Human cathelicidin, Ropocamptide) is a cathelicidin-related antimicrobial peptide with potent chemotactic and immunomodulatory properties. |
||
S4236 |
Proflavine HemisulfateProflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands. |
||
S3746 |
LumefantrineLumefantrine (benflumetol) is an antimalarial agent used to treat acute uncomplicated malaria. |
2021, AAC.02137-20 2020, 10.1021/acsinfecdis.0c00522 |
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S5212 |
Imidazolidinyl UreaImidazolidinyl Urea (Imidurea) is an antimicrobial agent used as preservative in cosmetics. |
||
S5210 |
Sulfamethazine Sodium SaltSulfamethazine (Sulfadimethyldiazine) is a sulfanilamide anti-infective agent used in the lifestock industry. |
||
S0443 |
DesciclovirDesciclovir (DCV, 6-Deoxyacyclovir, BW A515U) is a prodrug of the antiherpetic agent acyclovir (ACV) that converted into ACV by xanthine oxidase in humans. |
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S4678 |
Povidone iodinePovidone iodine (Betadine, PVP iodine, PVP-I, Isodine) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It is used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. |
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S9131 |
PunicalaginPunicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects. |
2020, 30;181(3):637-652.e15. 2020, 30;181(3):637-652e15 |
|
S3139 |
MethenamineMethenamine is an antibiotic used for the treatment of urinary tract infection. |
||
S5405 |
PropylparabenPropylparaben (Propyl 4-hydroxybenzoate, Propyl p-hydroxybenzoate, nipasol), a natural substance found in many plants and some insects, is an antimicrobial, preservative and flavouring agent. |
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S4242 |
Cetrimonium Bromide (CTAB)Cetrimonium Bromide (CTAB) is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts. |
2021, 10.1139/bcb-2020-0570 2018, 9(6) |
|
S5214 |
Imidocarb dipropionateImidocarb is an antiprotozoal agent, used as dipropionate in the treatment of babesiosis and ehrlichiosis. |
2017, 8(1):823 |
|
S6461 |
PermethrinPermethrin is a synthetic Type I pyrethroidal neurotoxic pesticide that has been responsible for accidental animal deaths. |
||
S3978 |
5-Phenyl-2,4-pentadienoic acid5-Phenyl-2,4-pentadienoic acid (5-Phenylpenta-2,4-dienoic acid) is used as Synthetic building block, anti-malarial agent. |
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S3220 |
TrigonellineTrigonelline (Trigenolline) is a plant alkaloid and a major component of coffee and fenugreek with anti-degranulation, anti-diabetic, antioxidant, anti-inflammatory, and neuroprotective effects. Trigonelline inhibits FcεRI-mediated intracellular signaling pathways, such as phosphorylation of PLCγ1, PI3K, and Akt. Trigonelline (Trigenolline) also inhibits the microtubule formation in RBL-2H3 cells. |
2021, 143:112204 |
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S5390 |
N-(Hytroxymethy)micotinamideN-(Hydroxymethyl)nicotinamide (Nikomethamide, Bilamid, N-hydroxymethylnicotinamide) is an antimicrobial agent. |
||
S5355 |
Piperaquine phosphatePiperaquine phosphate is an orally active bisquinolone antimalarial drug. |
||
S9560 |
Anisodamine HydrobromideAnisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs). |
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S5005 |
Cefotiam hydrochlorideCefotiam hydrochloride (Halospor, Pansporin, Pansporine) is the hydrochloride salt form of cefotiam and has a broad spectrum of activity against both gram-positive and gram-negative microorganisms. |
||
S1962 |
SulphadimethoxineSulphadimethoxine is a non-reducing glucuronide. |
||
S4555 |
CarsalamCarsalam (Carbonylsalicylamide) is a nonsteroidal anti-inflammatory drug. |
||
S7896 |
Sodium Tauroursodeoxycholate (TUDC)Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis. |
2019, 7(1):145 2019, 15(9):1905-1920 2018, 37:269-280 |
|
S4521 |
DEETDEET (N,N-Diethyl-meta-toluamide, diethyltoluamide) is a commen active ingredient insect repellent. |
||
S9185 |
Nitidine ChlorideNitidine Chloride, a benzophenanthridine alkaloid found in species of the genus Zanthoxylum, has an anti-malarial activity. |
2021, 101(Pt A):108273 2020, 14:216 |