Hydroxychloroquine Sulfate (NSC 4375)

For research use only. Not for use in humans.

製品コードS4430 別名:HCQ

Hydroxychloroquine Sulfate (NSC 4375)化学構造

CAS No. 747-36-4

Hydroxychloroquine Sulfate (NSC 4375, HCQ) is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.

サイズ 価格(税別)  
JPY 26400
JPY 38000
JPY 67900
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バルク問合せ

文献中Selleckの製品使用例(65)

製品安全説明書

Autophagy阻害剤の選択性比較

生物活性

製品説明 Hydroxychloroquine Sulfate (NSC 4375, HCQ) is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.
ターゲット
TLR9 [5] Autophagy [1]
体外試験

Hydroxychloroquine Sulfate is a potent inhibitor of autophagy. It prevents lysosomal acidification, thereby interfering with a key step in the autophagic process.HCQ treatment inhibits RCC (renal cell cancer) cell growth, promotes apoptosis, inhibits mitochondrial oxygen consumption, and increases rates of glycolysis[2].

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
Function assay M{\qemhGUy2EbIXlJINmdGy| NIXIXHhCdnSjZ3;ubZN1KGGldHn2bZR6KGG2IHj1cYFvKFSOUkmg[ZhxemW|c3XkJIlvKEiHSz3CcJVmKGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDDdGdDNWmwZIXj[YQhVkZva3HwdIFDKGyndnXsd{Bi\nSncjCyOEBpenNiYomgd5Bm[3S{b4Doc5RwdWW2cnnjJIFv[Wy7c3nzMEBKSzVyIE2gNE4yOSEQvF2u Ml25QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB{OUK4PVYoRjNyMkmyPFk3RC:jPh?=
Antiviral assay MXPW[ZJwKEV4IHPlcIx{ NX\DVmFvPDhiaB?= MXHJR|UxKG[xcjDhcpRqfmm{YXygZYN1cX[rdImgZYdicW6|dDDTRXJUNUOxVj2yJIlvKHSqZTDW[ZJwKEV4IHPlcIwhdGmwZTDheEA1QCCqIHL5JIludXWwb3\seY9z\XOlZX7j[U1j[XOnZDDhd5NigSBqZHX0[YN1cW6pIITo[UB3cXKjbDDOVEBxem:2ZXnuJIlvKHSqZTDueYNt\XW|IH;mJJRp\SCYZYLvJGU3KGOnbHzzLU4tKEmFNUCgQUAxNjZ5NkC4JO69VS5? M2LkOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzN{M{WzPFU6Lz5|MkO1N|g2QTxxYU6=
Function assay M3jlemhGUy2EbIXlJINmdGy| NYXse2N4SW62YXfvcol{fCCjY4Tpeol1gSCjdDDoeY1idiCWTGK3JIV5eHKnc4Pl[EBqdiCKRVutRox2\SClZXzsd{Bie3Onc4Pl[EBieyC{ZXT1Z5Rqd25iaX6gR2wzPjRvaX7keYNm\CCQRj3rZZBx[UJibHX2[Yx{KGGodHXyJFI1KGi{czDifUB{eGWldILvdIhwfG:vZYTybYMh[W6jbInzbZMtKEmFNUCgQUAxNjhizszNMi=> NV:2coRCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CyPVI5QTZpPkOwNlkzQDl4PD;hQi=>
Function assay MkXNTGVMOjl|IHPlcIx{ M3LweIhGWkdiYnnu[Ilv\yCjc4PhfZM7KESrc4DsZYNmdWWwdDDv[kBcO0ifLVTv[oV1cWyrZHWgLFUhdk1iZnnuZYwqKG[{b32gbGVTTyCvZX3idoFv\XNib3L0ZYlv\WRiZoLvcUBJTUt{OUOgZ4VtdHNuIFvpJF0hOi53MUG4PUDPxE1w MnvmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzJ|NUO4OVkoRjN{M{WzPFU6RC:jPh?=
Antiviral assay NYG2flN4XmW{bzDFOkBk\Wyucx?= MWPJR|kxKG[xcjDhcpRqfmm{YXygZYN1cX[rdImgZYdicW6|dDDTRXJUNUOxVj2yJIlvKHSqZTDW[ZJwKEV4IHPlcIwhdGmwZTDifUBu\WG|dYLpcochcW6oZXP0bY92eyC4aYLhcEB1cXSncjDv[kB{fXCncn7heIVvfCCocn;tJINwdXCxdX7kMZRz\WG2ZXSgWoVzdyCHNjDj[YxteyCkeTDN[YRq[W5iVHnzd5VmKEO3bIT1doUhUW6oZXP0bY92eyCGb4PlJEhVS0mGKUWwJIJ6KHSqZTDt[ZRpd2Rib3[gVoVm\CCjbnSgUZVmdmOqLDDJR|kxKD1iNT63PEDPxE1w MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{OjN3M{i1PUc,OzJ|NUO4OVk9N2F-
Antiproliferative assay NVTEVFlPSniSQ{OgZ4VtdHN? NVzkV4xyPzJiaILz NWDSb2lSSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDCfHBEOyClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKG2ndHjv[EwhUUN3MDC9JFM{KM7:TT6= NF\lUpU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NU[5PVE2Pyd-MkW2PVkyPTd:L3G+
qHTS assay NGPXN4xCPjd|IHPlcIx{ NILCcWxyUFSVIH;mJJBm\GmjdILpZ{Bk[W6lZYKgZ4VtdCCuaX7ld{B1dyCrZHXueIlngSCvdXz0bZBt\SCxcIDvdpR2dmm2aXXzJIZweiCmcoXnJJJmeHW{cH;zbY5oQiCScnntZZJ6KHOlcnXlckBnd3JiQU[3N{Bk\Wyucx?= M4jpXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEO1NVM6Lz5{OUSzOVE{QTxxYU6=
qHTS assay M2K3[WJVNTN5IHPlcIx{ MV3xTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW|IH\vdkBlenWpIILldJVzeG:|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhSlRvM{egZ4VtdHN? NXLs[INGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N|UyOzlpPkK5OFM2OTN7PD;hQi=>
qHTS assay M1XZenNMNU5vTVOgZ4VtdHN? MW\xTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW|IH\vdkBlenWpIILldJVzeG:|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhW0tvTj3NR{Bk\Wyucx?= NGDLOHY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N|UyOzl:L3G+
qHTS assay NVTDfFNTVkJvRVLjNUBk\Wyucx?= MYTxTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW|IH\vdkBlenWpIILldJVzeG:|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhVkJvRVLjNUBk\Wyucx?= MmDLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{WxN|koRjJ7NEO1NVM6RC:jPh?=
qHTS assay NIjzWHdNSU5vNTDj[Yxtew>? M1rWepFJXFNib3[gdIVlcWG2cnnjJINidmOncjDj[YxtKGyrbnXzJJRwKGmmZX70bYZ6KG23bITpdIxmKG:ycH;yeJVvcXSrZYOg[o9zKGS{dXegdoVxfXKyb4Ppcoc7KFC{aX3hdpkhe2O{ZXXuJIZweiCOQV6tOUBk\Wyucx?= NV2yNmcyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N|UyOzlpPkK5OFM2OTN7PD;hQi=>
Antiproliferative assay MoXKRVU1QSClZXzsdy=> NUHIeoU3OjVidXevcYw> MWGyNEBpenN? M{LFNmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIlvKGi3bXHuJGE2PDliY3XscJMh[XRiMkWgeYcwdWxidYCgeI8hOjBiaILzJIJ6KHiFRVzMbYdmdmOnIGLUR2EhW1BiYnHz[YQh[2WubIXsZZIhcW2yZXThcoNmKGGwYXz5d4l{ NFjOVnY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEW3NFk4Pyd-Mki1O|A6Pzd:L3G+
Antiproliferative assay NXvEZXl7STV2OTDj[Yxtew>? NXzIZo1UOjVidXevcYw> Mk\uOlAhcHK| NEHYbnpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBqdiCqdX3hckBCPTR7IHPlcIx{KGG2IEK1JJVoN22uIHHmeIVzKDZyIHjyd{BjgSC6Q1XMUIlo\W6lZTDSWGNCKFOSIHLhd4VlKGOnbHz1cIFzKGmvcHXkZY5k\SCjbnHsfZNqew>? NYL2PINrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki1O|A6PzdpPkK4OVcxQTd5PD;hQi=>
Autophagy assay MWfOR2kuUDNzMkKgZ4VtdHN? MV:yOUB1dyB3MDD1US=> MWG2JIhzew>? MU\Jcohq[mm2aX;uJI9nKGG3dH;wbIFogSCrbjDoeY1idiCQQ1mtTFMyOjJiY3XscJMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gdJVv[3SjdHWgUGM{KGW6cILld5Nqd25iYYSgNlUhfG9iNUCgeW0h[W[2ZYKgOkBpenNiYomg[ox2d3Knc3PlcoNmKG2rY4Lvd4NweGmlIHHuZYx6e2m| M1zC[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3Nkm5NVU4Lz5{NU[5PVE2PzxxYU6=
Apoptosis assay MV;IOFYxKGOnbHzz MnnZNlUhfG9iN{WgeW0> NWXWdFAyOjRiaILz NGm5UlRKdmS3Y4Tpc44hd2ZiYYDvdJRwe2m|IHnuJIh2dWGwIFi0OlAh[2WubIOgZZQhOjVidH:gO|UhfU1iYX\0[ZIhOjRiaILzJIJ6KGGwbnX4bY4uXiC|dHHpcolv\y2kYYPl[EBndG:5IHP5eI9u\XS{eR?= NHLld3g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NU[5PVE2Pyd-MkW2PVkyPTd:L3G+
Autophagy assay MmTBTFQ3OCClZXzsdy=> MVSyOEBpenN? MXvJcohq[mm2aX;uJI9nKGG3dH;wbIFogSCrbjDoeY1idiCKNE[wJINmdGy|IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKEyFMz2yJIxmfmWuIHH0JGlEPTBiYX\0[ZIhOjRiaILzJIJ6KGmvbYXuc4Jtd3RiYX7hcJl{cXN? NYnJVpdMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW2PVkyPTdpPkK1Olk6OTV5PD;hQi=>
Antiviral assay MXnW[ZJwKEV4IHPlcIx{ MVuyJIRigXN? NUHteZRDSW62aY\pdoFtKGWoZnnjZYN6KGGpYXnud5QhW0GUUz3Dc3YuOiBqc4TyZYlvKEKjdmDheFEqKGmwIG\ldo8hTTZiY3XscJMh[XO|ZYPz[YQh[nliaX7obYJqfGmxbjDv[kB3cXKjbDDSUmEhemWybHnjZZRqd25ibXXhd5Vz\WRiYomgVnQuWEOUIHHmeIVzKDJiZHH5d{whTUN3MDC9JFQvOTdizszNMi=> NYHybGM{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOTZ7MD:nQmNpTU2ETEyvZV4>
Antiviral assay M1zuXHZmem9iRU[gZ4VtdHN? MkTsN{Bl[Xm| MXPJR|UxKGSndHXycYlv[XSrb36gZZQhVU:LIECuNFA1KHW|aX7nJGNmdGyWaYTldk0hT2yxIDjDWGcqKGG|c3H5MEBx\XKob4Lt[YQhOyCmYYnzJJBwe3RvaX7m[YN1cW:wIHnuJHNCWlNvQ3;WMVIhcW6oZXP0[YQhXmW{bzDFOkBk\WyuczygTWM2OCB;IEmuNlEh|ryPLh?= MmLhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMNVY6OC9pPlPoSW1DVDxxYU6=
Antiviral assay NE\Be4dX\XKxIFW2JINmdGy| MV2zJIRigXN? Mn;tTWM2OCCmZYTldo1qdmG2aX;uJIF1KE2RSTCwMlAyKHW|aX7nJGNmdGyWaYTldk0hT2yxIDjDWGcqKGG|c3H5MEBx\XKob4Lt[YQhOyCmYYnzJJBwe3RvaX7m[YN1cW:wIHnuJHNCWlNvQ3;WMVIhcW6oZXP0[YQhXmW{bzDFOkBk\WyuczygTWM2OCB;IEGxMlE4KM7:TT6= NWrPN4ZRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOTZ7MD:nQmNpTU2ETEyvZV4>
Antiviral assay NFXObHNX\XKxIFW2JINmdGy| Ml7qNkBl[Xm| MYPBcpRqfmm{YXyg[YZncWOjY4mgZYdicW6|dDDTRXJUNUOxVj2yJEh{fHKjaX6gRoF3WGG2MTmgbY4hXmW{bzDFOkBk\WyuczDhd5Nme3OnZDDifUBqdmirYnn0bY9vKG:oII\pdoFtKFKQQTDy[ZBtcWOjdHnvckBu\WG|dYLl[EBjgSCUVD3QR3Ih[W[2ZYKgNkBl[Xm|LDDFR|kxKD1iMkWuOFkh|ryPLh?= Ml;JQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMNVY6OC9pPlPoSW1DVDxxYU6=

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アッセイ
Methods Test Index PMID
Western blot
p62 / LC3-I / LC3-II / GAPDH; 

PubMed: 31268153     


Effects of BC001 and/or HCQ on the expression of Beclin1, LC3 and p62. (C) The expression of p62 and LC3 in BGC823 cells treated with HCQ and/or BC001.

NLRP3 / β-actin; 

PubMed: 31775905     


NLRP3 expression in neutrophils. Neutrophils were pretreated with the indicated concentrations of hydroxychloroquine for 1 h and stimulated with SAA (10 μg/ml) for 24 h. Cellular lysates were analyzed by Western using anti-NLRP3 or anti-β-actin antibodies. Three experiments were performed using different neutrophils, and a representative result is shown.

p-NF-κB / β-actin; 

PubMed: 31775905     


Phosphorylation of NF-κB p65 in SAA-treated neutrophils. Neutrophils were pretreated with the indicated concentrations of hydroxychloroquine for 2 h and stimulated with SAA (10 μg/ml) for 20 min. Cells were lysed and cellular lysates were subjected to Western blot using anti-phosphor-NF-κB and β-actin antibodies. Data are representative of two independent experiments.

NOX2 / β-actin; 

PubMed: 32260307     


Western blot representative for NOX2 protein expression of HUVECs untreated (cont) or treated with 100 ng/mL TNF-α (a) or 20% preeclampsia (PE) sera (b) with or without apocynin (apo, 100 μM) or hydroxychloroquine (HCQ, 1 μg/mL). β-actin was used as a loading control.

31268153 31775905 32260307
IHC
HE staining of spleen tissue; 

PubMed: 29456648     


Hematoxylin and eosin staining of the spleen tissue in each group (magnification, ×400). PDS, prednisone; H-HCQ, high-dose hydroxychloroquine; L-HCQ, low-dose hydroxychloroquine; ART, artemisinin.

29456648
Immunofluorescence
ZO-1; 

PubMed: 32260307     


Immunofluorescent staining of ZO-1 on HUVECs treated with 100 ng/mL recombinant TNF-α or 20% preeclampsia sera for 16–22 h. Representative images from one of six experiments are shown. (A) Control untreated HUVECs, (B) TNF-α 100 ng/mL, (C) TNF-α 100 ng/mL with hydroxychloroquine 1 μg/mL, (D) control HUVECs treated with 20% normal pregnancy sera, (E) 20% preeclampsia sera, and (F) preeclampsia sera with hydroxychloroquine 1 μg/mL. Arrows show the ZO-1 staining on the endothelial cell border.

32260307
体内試験 The treatment of Hydroxychloroquine Sulfate reduces the infarct size in an in vivo rat model of I/R injury and the cardioprotective effect of Hydroxychloroquine is ERK1/2 dependent[3]. In addition, Hydroxychloroquine Sulfate shows an early vascular protective effect. HCQ seems to prevent the occurrence of endothelial dysfunction(ED) in treated animals[4].

お薦めの試験操作(参考用のみ)

キナーゼ試験:[2]
- 合併

In vitro kinase assays:

with purified proteins, recombinant S6 protein and recombinant active P70S6K are incubated in 1x kinase buffer with various amount of HCQ or RAD001 in the presence (25 μM) or absence of ATP for 30 minutes at 30°C. Total and phosphorylated S6 at ser235/236 and ser240/244 are detected by western analysis using phosphospecific antibodies. Note that recombinant GST-tagged S6 (53 kd) is distinguished from endogenous S6 (32 kd) on the western blot.
細胞試験: [2]
- 合併
  • 細胞株: Human RCC cell lines
  • 濃度: 75 or 100 μM
  • 反応時間: 48 h
  • 実験の流れ: All cells are cultured in RPMI with 10% FBS, 1% glutamine, and 1% Pen/Strep. cells are seeded on the appropriated plates overnight and treated with HCQ (75 or 100 μM) for 48 hours.
    (参考用のみ)
動物試験:[3]
- 合併
  • 動物モデル: Male Sprague Dawley (SD) rats
  • 投薬量: 200 mg/kg
  • 投与方法: oral administration
    (参考用のみ)

溶解度 (25°C)

体外 Water 67 mg/mL (154.39 mM)
DMSO Insoluble
Ethanol Insoluble

* 溶解度測定はSelleck技術部門によって行われており、その他文献に示されている溶解度と差異がある可能性がありますが、同一ロットの生産工程で起きる正常な現象ですからご安心ください。

化学情報

分子量 433.95
化学式

C18H28ClN3O5S

CAS No. 747-36-4
Storage powder
in solvent
別名 HCQ
Smiles CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O

投与溶媒組成計算器(クリア溶液)

ステップ1:実験データを入力してください。(実験操作によるロスを考慮し、動物数を1匹分多くして計算・調製することを推奨します)
投与量 mg/kg 動物平均体重 g 投与体積(動物毎) ul 動物数
ステップ2:投与溶媒の組成を入力してください。(ロット毎に適した溶解組成が異なる場合があります。詳細については弊社までお問い合わせください)
% DMSO % % Tween 80 % ddH2O
計算リセット

便利ツール

モル濃度計算器

モル濃度計算器

求めたい質量、体積または濃度を計算してください。

質量 (mg) = 濃度 (mM) x 体積 (mL) x 分子量 (g/mol)

モル濃度計算器方程式

  • 質量
    濃度
    体積
    分子量

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとSDS/COA(製品ページで利用可能な)。

希釈計算器

希釈計算器

貯蔵液を準備するために必要な希釈率を計算してください。Selleck希釈計算器は、以下の方程式に基づきます:

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます:C1V1 = C2V2 ( 入力 出力 )

  • C1
    V1
    C2
    V2

常に貯蔵液を準備するとき、小びんラベルとSDS/COA(オンラインで利用できる)で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

  • 連続希釈剤

  • 計算結果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください:

総分子量:g/mol

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

質量 濃度 体積 分子量

臨床試験

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04007562 Unknown status Drug: Hydroxychloroquine Sulfate LIPIN1 Deficiency Assistance Publique - Hôpitaux de Paris July 2019 --

技術サポート

ストックの作り方、阻害剤の保管方法、細胞実験や動物実験の際に注意すべき点など、製品を取扱う時に問い合わせが多かった質問に対しては取扱説明書でお答えしています。

Handling Instructions

他に質問がある場合は、お気軽にお問い合わせください。

  • * 必須

Autophagyシグナル伝達経路

Tags: Hydroxychloroquine Sulfate (NSC 4375)を買う | Hydroxychloroquine Sulfate (NSC 4375) ic50 | Hydroxychloroquine Sulfate (NSC 4375)供給者 | Hydroxychloroquine Sulfate (NSC 4375)を購入する | Hydroxychloroquine Sulfate (NSC 4375)費用 | Hydroxychloroquine Sulfate (NSC 4375)生産者 | オーダーHydroxychloroquine Sulfate (NSC 4375) | Hydroxychloroquine Sulfate (NSC 4375)化学構造 | Hydroxychloroquine Sulfate (NSC 4375)分子量 | Hydroxychloroquine Sulfate (NSC 4375)代理店
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細胞株 試験類型 濃度 培養時間 溶剤類型 活性叙述 PMID