Bacterial

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Bacterial製品

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Bacterial阻害剤 (66)
新製品

製品コード	製品名称	製品説明	文献中Selleckの製品使用例
S5159	Doxycycline	Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor.	Nat Genet, 2024, 56(1):124-135 Cell Rep, 2024, 43(2):113808 Nat Commun, 2023, 14(1):6885
S1373	Daptomycin	Daptomycin is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.	Molecules, 2023, 28(2)621 Infect Drug Resist, 2023, 16:4867-4879 Infect Drug Resist, 2023, 16:4867-4879
S1835	Azithromycin	Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.	Sci Rep, 2023, 13(1):14453 Sci Rep, 2023, 13(1):14453 J Pers Med, 2022, 12(2)258
S2335	Oridonin	Oridonin, a diterpenoid purified from Rabdosia rubescens, is a traditional agent with antitumor, anti-bacterial and anti-inflammatory effects. Oridonin inhibits AKT1 and AKT2 kinase activity with IC50 of 8.4 μM and 8.9 μM, respectively.	Inflammopharmacology, 2023, 31(4):1993-2005 J Immunol Res, 2023, 2023:5293677 J Immunother Cancer, 2022, 10(9)e005116
S1403	Tigecycline	Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline induces autophagy by downregulating the PI3K-AKT-mTOR pathway.	Antimicrob Agents Chemother, 2024, 68(3):e0112023 EBioMedicine, 2022, 87:104397 Microorganisms, 2022, 10(7)1421
S9046	Berberine	Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.	Phytomedicine, 2023, 117:154918 Pharmacol Res, 2022, 185:106489 Phytother Res, 2022, 10.1002/ptr.7490
S2908	Hygromycin B	Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.	Cell Death Dis, 2023, 14(6):348 Bio Protoc, 2022, 12(17)e4506 Autophagy, 2021, 1-17
S3021	Rimonabant (SR141716)	Rimonabant (SR141716) is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Rimonabant is also a dual inhibitor of acyl CoA:cholesterol acyltransferases(ACAT) 1 and 2 and inhibits mycobacterial MmpL3.	Toxicol Lett, 2023, 374:48-56 Int J Biol Sci, 2022, 18(4):1401-1414 Mol Metab, 2022, 65:101597
S1741	Rifabutin (LM427)	Rifabutin (LM427, Ansamycin) is a semisynthetic ansamycin antibiotic, used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.	Int J Mol Sci, 2022, 23(13)7383 Int J Mol Sci, 2022, 23(22)13809 ACS Infect Dis, 2022, 8(10):2171-2186
S2420	Aloperine	Aloperine is an isolated alkaloid in sophora plants such as Sophora alopecuroides L, and exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.	Cancer Cell Int, 2021, 21(1):662 Tissue Cell, 2021, 74:101706 J Cancer Res Clin Oncol, 2020, 10.1007/s00432-020-03157-2
S7894	Tunicamycin	Tunicamycin, an antibiotic, can potently inhibit the N-linked glycosylation (NLG) by competitively inhibiting UDP-GlcNAc-dolichol-phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) activity and can target several types of tumors by reducing angiogenesis, inhibiting colony formation, and enhancing TRAIL-induced apoptosis.	Cell Discov, 2023, 9(1):92 Cell Discov, 2023, 9(1):92 Adv Sci (Weinh), 2023, 10(25):e2300414
S1097	BTZ043 Racemate	BTZ043 racemate is a decaprenylphosphoryl-β-_D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.	Drug Deliv Transl Res, 2021, 11(4):1766-1778 J Med Chem, 2020, 28;63(10):5367-5386 Blood Adv, 2019, 3(5):797-812
S3015	Amoxicillin	Amoxicillin (Amoxycillin) is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms.	Ther Drug Monit, 2023, 10.1097/FTD.0000000000001100 J Pharm Biomed Anal, 2022, 219:114904 ChemMedChem, 2022, e202200043
S5535	Moxifloxacin	Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.	Microorganisms, 2022, 10(7)1421 Transl Vis Sci Technol, 2018, 7(2):11 J Pharmacol Toxicol Methods, 2017, 90:39-47
S5784	Vancomycin	Vancomycin is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria.	Infect Drug Resist, 2023, 16:4867-4879 Infect Drug Resist, 2023, 16:4867-4879 Ann Palliat Med, 2021, 10(2):1748-1754
S1399	Teicoplanin	Teicoplanin (Teichomycin,Targocid,MDL-507) is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria.	Front Microbiol, 2022, 13:884034 ACS Omega, 2022, 7(48):43657-43664 ACS Appl Mater Interfaces, 2020, 12(14):16150-16158
S1839	Chloroxine	Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.	Biosensors (Basel), 2023, 13(6)571 ACS Synth Biol, 2022, 11(8):2820-2828 Front Microbiol, 2020, 10:2936
S1502	Cephalexin	Cephalexin (Cefalexin) is an antibiotic that can treat a number of bacterial infections.	Clin Cancer Res, 2018, 24(3):659-673 Blood Cancer J, 2017, 10.1038/bcj.2017.61 Theranostics, 2017, 7(7):2092-2107
S2565	Amoxicillin Sodium	Amoxicillin Sodium (Clavulanate,Amoxycillin sodium) is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.	J Pharm Biomed Anal, 2022, 219:114904 ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489
S2575	Vancomycin HCl	Vancomycin HCl is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent.	Front Microbiol, 2022, 13:884034 Elife, 2021, 10e64237 Gut Microbes, 2020, 12(1):1-20
S5492	Econazole	Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.	Toxicol Appl Pharmacol, 2023, 475:116638 Acta Pharm Sin B, 2022, 12(7):3085-3102 Am J Cancer Res, 2020, 10(1):263-274
S1505	Aztreonam	Aztreonam (SQ 26776) is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.	Antimicrob Agents Chemother, 2023, 10.1128/aac.00921-23 PLoS Pathog, 2016, 12(10):e1005932 Expert Opinion on Orphan Drugs, 2013, 1(7):549-556
S1677	Chloramphenicol	Chloramphenicol (Chloromycetin) is a bacteriostatic by inhibiting protein synthesis.	Cell Rep, 2021, 34(3):108631 EMBO Rep, 2021, e53081 Oncotarget, 2018, 9(40):26086-26095
S4146	Bacitracin	Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis.	Onco Targets Ther, 2020, 13:9543-9558 Anal Chem, 2017, 89(16):8501-8508 Chem Res Toxicol, 2017, 30(10):1804-1814
S4848	Dalbavancin	Dalbavancin is a lipoglycopeptide antibiotic that has bactericidal activity against Gram-positive bacteria including various staphylococci.	Cell Rep, 2022, 39(11):110945 Front Microbiol, 2022, 13:884034 ACS Omega, 2022, 7(48):43657-43664
S4307	Auranofin	Auranofin (SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.	Adv Healthc Mater, 2023, e2300591. Theranostics, 2022, 12(12):5451-5469 Oncotarget, 2018,
S3121	Ornidazole	Ornidazole (Ro7-0207, NSC 95075) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.	Biomedicines, 2023, 10.3390/biomedicines11092576 Biomedicines, 2023, 11(9)2576 Microorganisms, 2022, 10(7)1421
S1773	Oxytetracycline (Terramycin)	Oxytetracycline(Terramycin) is a broad-spectrum tetracycline antibiotic, used to treat infections with bacteria.	Sci Rep, 2018, 8(1):7653 Front Microbiol, 2016, 7: 1765
S4004	Ethambutol 2HCl	Ethambutol 2HCl (CL40881) is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.	mBio, 2022, 13(4):e0167222 Molecules, 2019, 25(1)
S4093	Bismuth Subcitrate Potassium	Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.	Cell Rep, 2022, 38(6):110359 J Clin Invest, 2020, 130(7):3901-3918
S3122	Amikacin hydrate	Amikacin(BAY416651 hydrate) is an aminoglycoside antibiotic used to treat different types of bacterial infections.	Microorganisms, 2022, 10(7)1421 Molecules, 2019, 25(1)
S5105	Proanthocyanidins	Proanthocyanidins (PAs), also known as condensed tannins, are a class of polyphenols found in a variety of plants. They are very powerful antioxidants that remove harmful free oxygen radicals from cells.	Viruses, 2022, 14(2)353 Viruses, 2022, 14(4)764
S4029	Colistin Sulfate	Colistin (Polymixin E) is a cyclic cationic decapeptide linked to a fatty acid side chain, it belongs to a group of similarly structured bacterial antimicrobial peptides.	Front Pharmacol, 2021, 12:744494 Biogerontology, 2016, 17(5-6):907-920
S4148	Ampicillin Trihydrate	Ampicillin Trihydrate (NCI-C56086,D-(-)-α-Aminobenzylpenicillin trihydrate) is a β-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.	Front Vet Sci, 2022, 9:994652 Bone Joint Res, 2020, 16;9(4):152-161
S4959	Skatole	Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.	Nutrients, 2023, 15(6)1490 Exp Cell Res, 2022, 421(1):113373
S5298	Amoxicillin trihydrate	Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.	ChemMedChem, 2022, e202200043 PLoS Comput Biol, 2020, 16(12):e1008489
S4720	Cefotaxime	Cefotaxime(HR-756) is a third-generation cephalosporin antibiotic and has broad spectrum activity against Gram positive and Gram negative bacteria.	Biosensors (Basel), 2024, 14(3)129 J Biol Chem, 2023, 299(6):104710 Carleton University, 2023, 10.22215/etd/2023-15364
S5440	Berberine Sulfate	Berberine sulfate (Umbellatine), an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.	Front Pharmacol, 2021, 12:632201 Biology (Basel), 2021, 10(3)250
S4279	Demeclocycline HCl	Demeclocycline HCl(Demeclocycline hydrochloride) is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections.	J Biol Chem, 2020, 10.1074/jbc.RA119.011633. Sci Rep, 2018, 8(1):7653
S5007	Delamanid	Delamanid (OPC-67683) is a new anti-tuberculosis drug with an excellent intracellular bactericidal activity and a high accumulation rate.	Microbiol Spectr, 2023, e0046523. Front Immunol, 2021, 12:796677
S4854	Bedaquiline fumarate	Bedaquiline fumarate (TMC-207), an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.	Adv Healthc Mater, 2022, e2102117 Microorganisms, 2022, 10(7)1421
S2457	Clindamycin HCl	Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.	Proc Natl Acad Sci U S A, 2016, 113(50):14408-14413
S2568	Neomycin sulfate	Neomycin sulfate(Framycin sulfate) is an aminoglycoside antibiotic, used to treat bacteria infections.	Mol Cell, 2020, 22 pii: S1097-2765(20)30231-8
S1855	Pefloxacin Mesylate	Pefloxacin Mesylate(Pefloxacinium mesylate) is a synthetic chemotherapeutic agent and an antibacterial agent with IC50 of 6.7 nM.	J Biol Chem, 2019, 294(49):18624-18638
S1881	Protionamide	Protionamide (Prothionamide, 1321-TH) is a drug used in the treatment of tuberculosis.	Mol Imaging Biol, 2021, 10.1007/s11307-021-01689-8
S5051	Pipemidic acid	Pipemidic acid (Acido pipemidico) is a pyridopyrimidine antibiotic derivative of piromidic acid with activity against gram-negative bacteria including Pseudomonas aeruginosa and some gram-positive bacteria. Pipemidic acid is an inhibitor of DNA gyrase that is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA. It can be used for the research of intestinal, urinary, and biliary tract infections.	Hum Mol Genet, 2020, ddaa244
S5356	Ceftiofur	Ceftiofur is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.	Vet J, 2018, 234:24-26
S5199	Oxytetracycline hydrochloride	Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.	Front Microbiol, 2016, 7:1765
S4490	Tetracycline	Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.	PeerJ, 2022, 10:e13719
S5533	Tobramycin sulfate	Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.	Oncotarget, 2018, 9(40):26086-26095
S5008	Ciprofloxacin (CPX) hydrochloride	Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).	Nanomaterials (Basel), 2021, 11(8)1984
S2052	Oxytetracycline Dihydrate	Oxytetracycline Dihydrate is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.	Front Microbiol, 2016, 7:1765
S3496	Lefamulin acetate (Xenleta)	Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.	J Biol Chem, 2022, 298(5):101909
S6549	PBTZ169	PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1.	Cell Death Dis, 2019, 10(4):319
S3655	Cefepime Dihydrochloride Monohydrate	Cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intra-abdominal infections.	ACS Chem Neurosci, 2021, 10.1021/acschemneuro.1c00608
S5330	Amikacin Sulfate Salt	Amikacin (BAY 41-6551) sulfate, a semisynthetic analog of kanamycin, is an aminoglycoside antibiotic which is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains.	Microorganisms, 2022, 10(7)1421
S4198	Aminothiazole	Aminothiazole(2-Aminothiazole,2-Thiazolylamine) can be used as a thyroid inhibitor and it has antibacterial activity.	J Electroanal Chem (Lausanne), 2020, 878:114733
S3709	Furagin	Furagin (NF-416, F-35, Akritoin, Furazidin, Furazidine) is 2-substituted 5-nitrofuran, chemically and structurally similar to well-known antibacterial compound nitrofurantoin with antimicrobial activities.	J Clin Med, 2023, 12(16)5166
S4203	Furaltadone HCl	Furaltadone HCl(Altafur hydrochloride) is an antibacterial and has distinct curative effect in the treatment of coccidiosis.	Eur J Pharmacol, 2018, 828:119-125
S6411	Nimorazole	Nimorazole is a water soluble, 5-nitroimidazole compound with antibacterial and potential radiosensitizing activity.	Microorganisms, 2022, 10(7)1421
S3802	Trigonelline Hydrochloride	Trigonelline (Nicotinic acid N-methylbetaine, Coffearine, Gynesine), a major alkaloid component of fenugreek, has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and also has been shown to reduce diabetic auditory neuropathy and platelet aggregation.	Biomed Pharmacother, 2021, 143:112204
S5047	Methyl α-D-mannopyranoside	Methyl α-D-mannopyranoside can be used as an intermediate for chemical sythesis and is a competitor inhibitor of the binding of mannose by Escherichia coli.	mBio, 2022, e0217721
S5410	Chloramphenicol sodium succinate	Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity.	Oncotarget, 2018, 9(40):26086-26095
S5208	Ciprofloxacin hydrochloride hydrate	Ciprofloxacin Hydrochloride (Ciloxan, Ceprimax, Oftacilox,Bay-09867 hydrochloride hydrate) is the hydrochloride salt form of ciprofloxacin, which is an antibiotic used to treat a number of bacterial infections.	Nanomaterials (Basel), 2021, 11(8)1984
S3065	Amikacin disulfate	Amikacin sulfate (BB-K8) binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.	Microorganisms, 2022, 10(7)1421
S4528	Furazolidone	Furazolidone(Furoxone) is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria.	Kaohsiung J Med Sci, 2020, 10.1002/kjm2.12281
S4536	Nitrofurantoin	Nitrofurantoin (Macrodantin, Furadantine, Furadonine) is an antibiotic used to treat bladder infections.It inhibits bacterial DNA, RNA, and cell wall protein synthesis.	J Clin Med, 2023, 12(16)5166
S9135	Artemisic acid	Artemisic acid (Artemisinic acid), an amorphane sesquiterpene isolated from Artemisia annua L., has a variety of pharmacological activity, such as antimalarial activity, anti-tumor activity, antipyretic effect, antibacterial activity, allelopathy effect and anti-adipogenesis effect.	ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S0906	6-Methoxydihydrosanguinarine	6-Methoxydihydrosanguinarine is an lkaloid isolated from the fruits of M.cordata. 6-Methoxydihydrosanguinarine shows strong cytotoxicity against MCF-7 and SF-268 cell lines with IC50 values of 0.61 μM and 0.54 μM, respectively.	Phytomedicine, 2022, 102:154164
S1162	Pretomanid (PA-824)	PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.
S1370	Biapenem	Biapenem (L-627, LJC10627) is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacterial strains.
S1768	Cefditoren Pivoxil	Cefditoren Pivoxil (ME-1207) is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria.
S1605	Cefdinir	Cefdinir (FK 482, PD 134393, CI-983) is an oral cephalosporin antibiotic, used to treat bacterial infections in many different parts of the body.	Cancers (Basel), 2023, 15(8)2373
S2544	Cefprozil hydrate	Cefprozil hydrate is a semi-synthetic broad-spectrum cephalosporin antibiotic, used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin.
S2563	Oxacillin sodium monohydrate	Oxacillin sodium monohydrate (Methicillin) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.
S3129	Trimethoprim	Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
S1915	Sulfamethoxazole	Sulfamethoxazole(Ro 4-2130) is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.
S1762	Pyrazinamide	Pyrazinamide (Pyrazinoic Acid Amide) is an agent used to treat tuberculosis.
S1791	Bacitracin Zinc	Bacitracin(Zinc Bacitracin) is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.
S2543	Ceftiofur HCl	Ceftiofur HCl (U-67279A,Excenel hydrochloride) is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection.
S1916	Sulfisoxazole	Sulfisoxazole (NU-445) is a sulfonamide antibacterial with an oxazole substituent.
S3195	Azlocillin sodium salt	Azlocillin is an acylampicillin with a broad spectrum against bacteria.
S1618	Sulfameter	Sulfameter is a long-acting sulfonamide antibacterial.
S1957	Sulfamethizole	Sulfamethizole is a sulfathiazole antibacterial agent.
S3133	Sulfamethazine	Sulfamethazine(Sulfadimidine,Sulfadimerazine) is a sulfonamide antibacterial.
S1685	Sulfanilamide	Sulfanilamide (Sulphanilamide) is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.
S3179	Carbenicillin disodium	Carbenicillin (BRL-2064,α-carboxybenzylpenicillin) is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.
S3193	Ticarcillin sodium	Ticarcillin (AB 2288, BRL 2288) is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
E2970^New	Gramicidin	Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is an antimicrobial peptide that destroys gram-positive bacteria. It inhibits the growth of bacteria by forming pores and channels in the cell wall, which increase its permeability to monovalent cations.
S5227	Erythromycin thiocyanate	Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
S5352	Cefminox Sodium	Cefminox Sodium (Meicelin, MT-141) is the sodium salt form of cefminox, a semi-synthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity.
S6235	Sodium dehydroacetate	Sodium dehydroacetate is the sodium salt of dehydroacetic acid, a fungicide and bactericide that is commonly used as a food preservative. Sodium dehydroacetate is a preservative that is used in the formulation of cosmetics and personal care products in order to extend the shelf-life by preventing microbial contamination.
S3621	Pazufloxacin mesylate	Pazufloxacin Mesylate (T-3762, Pazucross), also known as Pazucross and T-3762, is a quinolone antibacterial agent used for the intravenous therapy of several infections.
S5560	Midecamycin	Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.
S5406	Sultamicillin Tosylate	Sultamicillin Tosylate is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant.
S5048	Fosfomycin Disodium	Fosfomycin (Phosphonemycin) is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis.
S4576	Sulfabenzamide	Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) is an antibacterial/antimicrobial which also exhibit their antitumor effects through multiple mechanisms including inhibition of membrane bound carbonic anhydrases, prevention of microtubule assembly, cell cycle arrest, and inhibition of angiogenesis.
S5353	Cefpiramide sodium	Cefpiramide sodium (CPMS, SM-1652,wy-44635) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients.
S5081	Ceforanide	Ceforanide is a new cephalosporin with antibacterial activity and has a longer elimination half-life than any currently available cephalosporin.
S5951	Cefoxitin	Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
S3295	Taxifolin 7-rhamnoside	Taxifolin 7-rhamnoside (TR, Taxifolin 7-O-rhamnoside, Taxifolin 7-O-α-L-rhamnoside), a flavonoid isolated from Hypericum japonicum, shows antibacterial activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
S2596	Clindamycin palmitate HCl	Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.
S5012	Octenidine Dihydrochloride	Octenidine, a cationic surfactant, is active against gram-positive and gram-negative bacteria.
S2830	Clindamycin	Clindamycin inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
S3623	Ceftibuten dihydrate	Ceftibuten Dihydrate(Sch-39720 dihydrate) is the dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity.
S4850	Flucloxacillin sodium	Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.
S9224	Dehydroandrographolide Succinate	Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.
S4846	Meropenem Trihydrate	Meropenem is a broad-spectrum antibacterial agent of the carbapenem family with a broad spectrum of in vitro activity against Gram-positive and Gram-negative pathogens.
S9226	Steviolbioside	Steviolbioside (CCRIS-6025), a natural sweetener, exhibits moderate antituberculosis activity against M. tuberculosis strain H37RV in vitro.
S4594	Cephalothin sodium	Cephalothin (Cefalotin, Cephalotin) sodium is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.
S5941	Besifloxacin	Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis.
S3703	Phenethyl alcohol	Phenethyl alcohol (2-phenylethanol, 2-Phenylethyl alcohol, Benzeneethanol, Phenylethanol) is an antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
S5186	Cefpiramide	Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) is a pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.
S4880	Cefathiamidine	Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.
S5268	Solithromycin	Solithromycin (CEM-101, OP-1068), belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
S0534	PK150	PK150 is an analogue of Sorafenib, which shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 µM, respectively.
S1617	Sulfapyridine	Sulfapyridine is a sulfonamide antibacterial.
S5332	Cefquinome sulfate	Cefquinome sulphate is a veterinary, parenteral, and fourth-generation cephalosporin. Its antimicrobial potency and extensive antibacterial spectrum result from the introduction of a methoxyimino-aminothiazolyl moiety into the acyl side chain.
S5278	Tedizolid	Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.
E0365	Fucoidan	Fucoidan is an anionic sulfated polysaccharide extracted from marine brown algae with a large range of biological activities, including anti-inflammatory, anti-cancer, anti-viral, anti-oxidation, anticoagulant, antithrombotic, anti-angiogenic and anti-Helicobacter pylori, etc.
S5532	Erythromycin estolate	Erythromycin (Lubomycine B), a naturally occurring macrolide, is derived from Streptomyces erythrus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S5495	Ceftiofur sodium	Ceftiofur sodium is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.
S5625	Ammonium lactate	Ammonium lactate (Lac-hydrin) is the ammonium salt of lactic acid with mild anti-bacterial properties.
S4869	Sulfamethoxazole sodium	Sulfamethoxazole sodium is an antibiotic used for bacterial infections.
S5054	Rifamycin sodium salt	Rifamycin sodium is an antibacterial drug used for treatment of mycobacterium infections.
S3499	Monocaprylin	Monocaprylin (2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol, MC) exhibits an excellent antibacterial activity against Staphylococcus aureus and Escherichia coli.
S5491	Lomefloxacin	Lomefloxacin(SC47111A) is a fluoroquinolone antibiotic used to treat bacterial infections.
S5331	Ceftezole sodium	Ceftezole Sodium (Celoslin sodium, Falomesin sodium) is the sodium salt form of ceftezole, a semi-synthetic first-generation cephalosporin with antibacterial activity.
S4595	Cefazolin Sodium	Cefazolin Sodium (cefazoline, cephazolin, Ancef) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
S5936	Cefazolin	Cefazolin(Cephazolin) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
S4596	Cefixime	Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin.
S7550	Erythromycin Cyclocarbonate	Erythromycin Cyclocarbonate(Davercin), derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.
S4875	Cephapirin Benzathine	Cephapirin Benzathine is the benzathine salt form of cephapirin, which is a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity.
S4885	Taurolidine	Taurolidine (Taurolin, Tauroline, Tauroflex) is a synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities.
S4861	Oxindole	Oxindole (2-indolone, 2-Oxindole, Indolin-2-one) is an aromatic heterocyclic organic compound which causes sedation, muscle weakness, hypotension, and coma when dosed in excess.
S3142	Potassium sorbate	Potassium sorbate (Sorbic acid potassium) is a nonpoisonous food preservative isolated from Sorbus aucuparia. Potassium sorbate is an effective inhibitor of most molds and yeasts and some bacteria.
E0010	Hypocrellin A	Hypocrellin A (HA) is a perylenequinone isolated from Shiraia bambusicola that shows antiviral, antimicrobial and anticancer activity through mediating multiple signaling pathways. Hypocrellin A also is a selective and potent inhibitor of PKC.
S4647	Cefmenoxime hydrochloride	Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.
S4874	Cefazedone	Cefazedone (Refosporen, Cefazedonum) is a semisynthetic first-generation cephalosporin with antibacterial activity.
S6867	Glyceryl monocaprate (Monocaprin)	Monocaprin (Glyceryl caprate) is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.
S4602	Acetohydroxamic acid	Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.
S0715	ML406	ML406 is a small molecule probe that shows anti-tubercular activity via M.tuberculosis BioA (DAPA synthase) enzyme inhibition with an IC50 of 30 nM.
S9466	Methenamine Hippurate	Methenamine Hippurate is the hippurate salt form of methenamine, a prodrug and inactive weak base that is hydrolyzed to formaldehyde in acid urine.Methenamine Hippurate is the component of Hiprex drug which has antibacterial activity.
S9292	Dictamnine	Dictamnine, a natural plant product, has been reported to have antimicrobial activity against bacteria and fungi.
S5296	Cephradine monohydrate	Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
S5487	Cefoperazone sodium	Cefoperazone(CP 52640-2) Sodium is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.
S4822	Silver Sulfadiazine	Silver sulfadiazine is a bactericidal for many gram- negative and gram-positive bacteria as well as being effective against yeast.
S5736	Benzathine penicilline	Benzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections.
S1884	Sparfloxacin	Sparfloxacin (AT-4140, CI-978, PD 131501,Zagam) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.
S2385	Hordenine	Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.
S4634	Sodium sulfadiazine	Sodium Sulfadiazine (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.
S5291	sulfaisodimidine	Sulfaisodimidine (Sulfamethin) is a sulfonamide antibacterial.
S5235	Cefodizime	Cefodizime (CEF, CDZ) is an aminothiazolyl cephalosporin with a broad spectrum of antibacterial activity.
S5417	Spectinomycin dihydrochloride pentahydrate	Spectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome.
S3644	Sulfamonomethoxine	Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
S5546	Sulfacetamide	Sulfacetamide (Acetosulfamine) is a synthetic sulfanylacetamide derivative with bacteriostatic activity. It is an anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
S4179	Mezlocillin Sodium	Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.
S4060	Erythromycin Ethylsuccinate	Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
S5515	Penicillin G Procaine	Procaine benzylpenicillin (Procaine benzylpenicillin,PGP), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
S5289	Ceftezole	Ceftezole (Celoslin, Falomesin) is a semi-synthetic first-generation cephalosporin with antibacterial activity.
S6872	Merbromin	Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the K_M and decreasing the K_cat of 3CLpro.
S5637	Cefotiam Hexetil Hydrochloride	Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.
S5638	Cefozopran hydrochloride	Cefozopran Hydrochloride is the hydrochloride salt form of cefozopran, a semi-synthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity.
S5644	Ceftriaxone Sodium	Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.	Biosensors (Basel), 2024, 14(3)129
S8871	Omadacycline tosylate	Omadacycline tosylate(PTK 0796 tosylate,Amadacycline tosylate) is a first-in-class aminomethylcycline antibiotic, demonstrating antimicrobial activity in vitro against a range of Gram-positive and Gram-negative aerobes and some anaerobic bacteria.
S5420	Clindamycin alcoholate	Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S4750	Sulfacetamide sodium salt hydrate	Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.
S6584	Amdinocillin	Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms.
E0052	Merafloxacin	Merafloxacin (CI-934) is a fluoroquinolone antibacterial thats inhibit -1 frameshifting efficiency of SARS-CoV-2 and other betacoronaviruses.
S3636	Cefadroxil hydrate	Cefadroxil(BL-S 578 hydrate) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
S3637	Cefpirome sulfate	Cefpirome(HR-810 sulfate) is a fourth-generation cephalosporin and is considered highly active against Gram-negative bacteria.
S3638	Cefamandole nafate	Cefamandole Nafate is the sodium salt form of cefamandole formyl ester. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall, interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
S3350	Cholesteryl linoleate	Cholesteryl linoleate is less polar lipid in human nasal fluid that contributes to the inherent antibacterial activity.
S0147	KKL-10	KKL-10 is an inhibitor of ribosome rescue that exhibits exceptional broad-spectrum antimicrobial activity against bacteria.
S4983	Sorbic acid	Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
S0843	Filastatin	Filastatin, a long-lasting inhibitor of Candida albicans filamentation, inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay.
S3708	Sulfachloropyridazine	Sulfachloropyridazine is an antibiotic used to treat a variety of bacterial infections.
S4201	Florfenicol	Florfenicol (SCH-25298,(-)-Florfenicol) is a fluorinated synthetic analog of thiamphenicol with broad-spectrum, primarily bacteriostatic activity.
S4663	Fusidate Sodium	Fusidate Sodium (Fucidin, SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
S3710	Fosfomycin calcium	Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
S4986	Latamoxef sodium	Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects.
S6031	2,6-Dihydroxybenzoic acid	2,6-Dihydroxybenzoic acid (γ-resorcylic acid, 2-Carboxyresorcinol, 2,6-Resorcylic acid) is a phenolic compound which is known to have poor biological performance such as DPPH scavenging activity and microbial growth inhibition.
S5166	Benzoyleneurea	Benzoyleneurea (2,4-Dihydroxyquinazoline, Quinazolinedione, Quinazoline-2,4-diol) scaffold is used in the synthesis of novel protein geranylgeranyltransferase-I inhibitors.
S3058	Danofloxacin Mesylate	Danofloxacin (CP-76136-27) is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM.
S4271	Isepamicin Sulphate	Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit.
S3672	Cefonicid sodium	Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.
S6090	JFD01307SC	JFD01307SC ([(1,1-dioxidotetrahydrothien-3-yl)amino]acetic acid) shows activity against M.tuberculosis with minimum inhibitory concentrations (MICs) in the range of 8 to 16 µg/ml. JFD01307SC may targets enzymes involved in glutamine biosynthesis.
S4213	Dirithromycin	Dirithromycin (LY-237216, ASE 136,Dynabac) is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides.
E4353^New	Ampicillin	Ampicillin (D-(-)-alpha-Aminobenzylpenicillin) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. It exhibits a good minimum inhibitory concentration for Staphylococcus aureus, Escherichia coli, Hemophilus influenzae, and Streptococcus pneumoniae with MICs of 0.6–1 mg/L, 4 mg/L, 0.25 mg/L, and 0.03-0.06 mg/L, respectively.
S4216	Valnemulin HCl	Valnemulin HCl is a broad-spectrum bacteriostatic agent inhibiting protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.
E0828	Mitonafide	Mitonafide inhibits the activity of Mycobacterium tuberculosis NAD+ dependent DNA ligase A at concentrations of 50 µM.
E0816	Oritavancin Diphosphate	Oritavancin Diphosphate is an orally active glycopeptide antibiotic which is active against Gram-positive bacteria and also has antibacterial activity against multidrug-resistant Streptococcus pneumoniae.
S4105	Closantel Sodium	Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
S5070	Mupirocin calcium	Mupirocin Calcium (Pseudomonic acid A) is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens,which inhibits bacterial protein synthesis and is used as an antibiotic.
S4106	Closantel	Closantel (R-31520,nsc 335306) is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.	J Fungi (Basel), 2024, 10(2)131
S3712	Tulathromycin A	Tulathromycin A is a novel long-acting semi-synthetic tribasic macyocyclic antibiotic of the triamilide group and used for the treatment of pulmonary diseases of swine and cattle.
S6067	2,4-dichlorobenzyl alcohol	2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections.
S9099	Orientin	Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.
S5776	Proflavine	Proflavine (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria. It is a topical antiseptic used mainly in wound dressings.
S6444	Triclocarban	Triclocarban is an antibacterial agent common used in personal care products.
S3650	Penicillin V potassium salt	Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
S0423	GSK2200150A	GSK2200150A is identified by high-throughput screening (HTS) campaign that can be used as an anti-tuberculosis (TB) agent (MIC = 0.38 µM).
S9328	5,6,7-Trimethoxyflavone	5,6,7-Trimethoxyflavone (Baicalein Trimethyl Ether), methylations of the hydroxyl groups of oroxylin A or baicalein, has various pharmacological activities including antiviral, anticancer and antibacterial.
E2952^New	2-Chloroacetamide	2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase.
S6464	Ftaxilide	Ftaxilide is a novel antituberculosis agent.
S5924	Olanexidine Hydrochloride semihydrate	Olanexidine (OPB-2045, OPB-2045G) is a monobiguanide compound with bactericidal activity.
S0195	Walrycin B	Walrycin B is an antibacterial compound and a potent inhibitor of WalR targeting the WalR response regulator.
S4517	Cefotaxime sodium	Cefotaxime sodium salt(HR-756) is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.	Biosensors (Basel), 2024, 14(3)129
S9122	Tectorigenin	Tectorigenin (TEC) is an isoflavone isolated from various medicinal plants, such as Pueraria thunbergiana Benth, Belamcanda chinensis, and Iris unguicularis. It has been reported to exert pharmacological actions, including antitumor and antibacterial effects, free radical neutralization, and selective estrogen receptor modulation.
S4518	Chloroxylenol	Chloroxylenol is a broad-spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.
S5209	Enoxacin Sesquihydrate	Enoxacin sesquihydrate (Enoxacin hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
S9377	Eugenyl acetate	Eugenyl acetate, an aromatic component of clove essential oil, exhibits various pharmacological activities, including antibacterial and anti-virulence activities against drug-resistant A. baumannii clinical isolates.
S3132	Sulfamerazine	Sulfamerazine (RP 2632,sulphamerazine) is a sulfonamide antibacterial.
S4523	Dihydrostreptomycin sulfate	Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep. Dihydrostreptomycin is a derivative of streptomycin.
S5473	Pivmecillinam hydrochloride	Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections.
S5202	Quinocetone	Quinocetone is a novel veterinary chemicals that is also bacteriocide and potential anti-tumor agent.
S4780	7-Methoxy-4-methylcoumarin	7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label.
S5201	Acetylisovaleryltylosin Tartrate	Acetylisovaleryltylosin tartrate (AK105039) is an antimicrobial of the macrolide group with antibacterial activity against Gram-positive bacteria.
S5211	4-Aminosalicylic acid	4-Aminosalicylic acid (Para-aminosalicylic acid, Aminosalicylic acid, 4-aminosalicylate) is an antitubercular agent with bacteriostatic activity against Mycobacterium tuberculosis.
S4833	Cefoxitin sodium	Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
S9136	Neochlorogenic acid	Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.
S5350	Cefpodoxime proxetil	Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.
S5095	Olaquindox	Olaquindox (Bisergon, Bayernox, Bayonox, Olachindox) is an oral anti-bacterial agent used as an additive to animal food.
S4544	Urethane	Urethane (Carbamic acid ethyl ester, Ethyl carbamate, Ethylurethane) is a kind of antineoplastic agent that is also used as a veterinary anesthetic. It is a intermediate in organic synthesis.	DSpace, 2023, Volume 30 Issue 11
S4425	Rifamycin S	Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation.
S4813	Cefuroxime axetil	Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.
S4436	Pleuromutilin	Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
S4393	Cephapirin Sodium	Cephapirin Sodium (Cefapirin) is the sodium salt form of cephapirin, a semi-synthetic, first-generation cephalosporin antibiotic with bactericidal activity.Cephapirin Sodium is effective against gram-negative and gram-positive organisms.
S4547	8-Hydroxyquinoline	8-Hydroxyquinoline (8-Oxychinolin, 8-Quinolinol, Oxine) is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes.
S5354	Cefteram pivoxil	Cefteram Pivoxil is the pivalate ester prodrug of cefteram, a semi-synthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity.
S3280	Linderene	Linderene (Lindenenol) is a furanosesquiterpenoid isolated from Lindera pulcherrima with antibacterial and antioxidant activities.
S4550	Azelaic acid	Azelaic acid (Nonanedioic acid, Finacea, Azelex, Anchoic acid) is an organic compound produced by the ozonolysis of oleic acid and possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity.
S4844	Cefcapene Pivoxil Hydrochloride	Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity.
E0515	Cefatrizine	Cefatrizine, a broad-spectrum, semisynthetic, first-generation cephalosporin with antibacterial activity, binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
S4553	Bronopol	Bronopol (2-bromo-2-nitropropane-1,3-diol) is antibacterial agent, used as preservative in cosmetic industry.
S7739	Telacebec	Telacebec is a novel antituberculosis drug that targets Mycobacterium tuberculosis cellular energy production through inhibition of the mycobacterial cytochrome bc1 complex. Telacebec (Q203, IAP6) is active against Mycobacterium tuberculosis H37Rv with MIC50 of 2.7 nM in culture broth medium.
S5863	Metronidazole Benzoate	Metronidazole Benzoate (Benzoyl metronidazole) is the benzoate ester of metronidazole, a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
S4404	Pasiniazid	Pasiniazid(Paraniazide,Pasiniazide) is a composition of isoniazid and 4-aminosalicylic acid, used to treat tuberculosis patients.
S4522	Dehydroacetic acid	Dehydroacetic acid (Biocide 470F, Methylacetopyronone) is an organic compound, used mostly as a fungicide and bactericide.
S4408	Procodazole	Procodazole (Propazol, 2-Benzimidazolepropionic acid, 3-(1H-benzimidazole-2) propanoic acid) is used as a potentiator which is non-specific active immunoprotective against viral and bacterial infections.
S4565	Diiodohydroxyquinoline	Diiodohydroxyquinoline (Iodoquinol) is a topical therapeutic agent,a quinoline derivative, with satisfactory antibacterial properties.
S5456	Isobavachalcone	Isobavachalcone (Corylifolinin), a naturally occurring chalcone compound derived from the seeds of Psoralea corylifolia L., has long been used in traditional Chinese medicine as anthelmintic, antibacterial, aphrodisiac, astringent and antiplatelet agent.
S2908	Hygromycin B	Hygromycin B (Hygrovetine), a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.	Cell Death Dis, 2023, 14(6):348 Bio Protoc, 2022, 12(17)e4506 Autophagy, 2021, 1-17
S3021	Rimonabant (SR141716)	Rimonabant (SR141716) is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Rimonabant is also a dual inhibitor of acyl CoA:cholesterol acyltransferases(ACAT) 1 and 2 and inhibits mycobacterial MmpL3.	Toxicol Lett, 2023, 374:48-56 Int J Biol Sci, 2022, 18(4):1401-1414 Mol Metab, 2022, 65:101597
S7894	Tunicamycin	Tunicamycin, an antibiotic, can potently inhibit the N-linked glycosylation (NLG) by competitively inhibiting UDP-GlcNAc-dolichol-phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) activity and can target several types of tumors by reducing angiogenesis, inhibiting colony formation, and enhancing TRAIL-induced apoptosis.	Cell Discov, 2023, 9(1):92 Cell Discov, 2023, 9(1):92 Adv Sci (Weinh), 2023, 10(25):e2300414
S1677	Chloramphenicol	Chloramphenicol (Chloromycetin) is a bacteriostatic by inhibiting protein synthesis.	Cell Rep, 2021, 34(3):108631 EMBO Rep, 2021, e53081 Oncotarget, 2018, 9(40):26086-26095
S4307	Auranofin	Auranofin (SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.	Adv Healthc Mater, 2023, e2300591. Theranostics, 2022, 12(12):5451-5469 Oncotarget, 2018,
S5105	Proanthocyanidins	Proanthocyanidins (PAs), also known as condensed tannins, are a class of polyphenols found in a variety of plants. They are very powerful antioxidants that remove harmful free oxygen radicals from cells.	Viruses, 2022, 14(2)353 Viruses, 2022, 14(4)764
S4854	Bedaquiline fumarate	Bedaquiline fumarate (TMC-207), an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.	Adv Healthc Mater, 2022, e2102117 Microorganisms, 2022, 10(7)1421
S2457	Clindamycin HCl	Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.	Proc Natl Acad Sci U S A, 2016, 113(50):14408-14413
S1881	Protionamide	Protionamide (Prothionamide, 1321-TH) is a drug used in the treatment of tuberculosis.	Mol Imaging Biol, 2021, 10.1007/s11307-021-01689-8
S5199	Oxytetracycline hydrochloride	Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.	Front Microbiol, 2016, 7:1765
S4490	Tetracycline	Tetracycline (TC) is a broad-spectrum antibiotic that exhibits activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.	PeerJ, 2022, 10:e13719
S5008	Ciprofloxacin (CPX) hydrochloride	Ciprofloxacin (CPX) hydrochloride, a fluorinated quinolone, is a β-diketone antibiotic with a broad spectrum antibacterial activity. Ciprofloxacin is an inhibitor of bacterial DNA gyrase (a subclass of Type II topoisomerases).	Nanomaterials (Basel), 2021, 11(8)1984
S3496	Lefamulin acetate (Xenleta)	Lefamulin acetate (Xenleta, BC-3781 acetate) is a pleuromutilin antibiotic for community-acquired bacterial pneumonia (CABP) treatment. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, thus preventing the binding of transfer RNA for peptide transfer.	J Biol Chem, 2022, 298(5):101909
S6549	PBTZ169	PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1.	Cell Death Dis, 2019, 10(4):319
S4198	Aminothiazole	Aminothiazole(2-Aminothiazole,2-Thiazolylamine) can be used as a thyroid inhibitor and it has antibacterial activity.	J Electroanal Chem (Lausanne), 2020, 878:114733
S5047	Methyl α-D-mannopyranoside	Methyl α-D-mannopyranoside can be used as an intermediate for chemical sythesis and is a competitor inhibitor of the binding of mannose by Escherichia coli.	mBio, 2022, e0217721
S1162	Pretomanid (PA-824)	PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.
S1762	Pyrazinamide	Pyrazinamide (Pyrazinoic Acid Amide) is an agent used to treat tuberculosis.
S1791	Bacitracin Zinc	Bacitracin(Zinc Bacitracin) is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, a membrane carrier molecule that transports the building-blocks of the peptidoglycan bacterial cell wall outside of the inner membrane. It inhibits cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.
S1618	Sulfameter	Sulfameter is a long-acting sulfonamide antibacterial.
S1685	Sulfanilamide	Sulfanilamide (Sulphanilamide) is a competitive inhibitor for bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.
E2970^New	Gramicidin	Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is an antimicrobial peptide that destroys gram-positive bacteria. It inhibits the growth of bacteria by forming pores and channels in the cell wall, which increase its permeability to monovalent cations.
S3295	Taxifolin 7-rhamnoside	Taxifolin 7-rhamnoside (TR, Taxifolin 7-O-rhamnoside, Taxifolin 7-O-α-L-rhamnoside), a flavonoid isolated from Hypericum japonicum, shows antibacterial activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).
S2596	Clindamycin palmitate HCl	Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.
S2830	Clindamycin	Clindamycin inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
S9226	Steviolbioside	Steviolbioside (CCRIS-6025), a natural sweetener, exhibits moderate antituberculosis activity against M. tuberculosis strain H37RV in vitro.
S3703	Phenethyl alcohol	Phenethyl alcohol (2-phenylethanol, 2-Phenylethyl alcohol, Benzeneethanol, Phenylethanol) is an antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
S5186	Cefpiramide	Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) is a pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.
S0534	PK150	PK150 is an analogue of Sorafenib, which shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 µM, respectively.
E0365	Fucoidan	Fucoidan is an anionic sulfated polysaccharide extracted from marine brown algae with a large range of biological activities, including anti-inflammatory, anti-cancer, anti-viral, anti-oxidation, anticoagulant, antithrombotic, anti-angiogenic and anti-Helicobacter pylori, etc.
S5495	Ceftiofur sodium	Ceftiofur sodium is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.
S3499	Monocaprylin	Monocaprylin (2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol, MC) exhibits an excellent antibacterial activity against Staphylococcus aureus and Escherichia coli.
S7550	Erythromycin Cyclocarbonate	Erythromycin Cyclocarbonate(Davercin), derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.
S4861	Oxindole	Oxindole (2-indolone, 2-Oxindole, Indolin-2-one) is an aromatic heterocyclic organic compound which causes sedation, muscle weakness, hypotension, and coma when dosed in excess.
S3142	Potassium sorbate	Potassium sorbate (Sorbic acid potassium) is a nonpoisonous food preservative isolated from Sorbus aucuparia. Potassium sorbate is an effective inhibitor of most molds and yeasts and some bacteria.
E0010	Hypocrellin A	Hypocrellin A (HA) is a perylenequinone isolated from Shiraia bambusicola that shows antiviral, antimicrobial and anticancer activity through mediating multiple signaling pathways. Hypocrellin A also is a selective and potent inhibitor of PKC.
S4647	Cefmenoxime hydrochloride	Cefmenoxime (SCE-1365), a potent inhibitor of Enterobacteriaceae, is a cephalosporin antibiotic that is administered intravenously or intramuscularly.
S6867	Glyceryl monocaprate (Monocaprin)	Monocaprin (Glyceryl caprate) is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.
S4602	Acetohydroxamic acid	Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.
S6872	Merbromin	Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the K_M and decreasing the K_cat of 3CLpro.
S6584	Amdinocillin	Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms.
E0052	Merafloxacin	Merafloxacin (CI-934) is a fluoroquinolone antibacterial thats inhibit -1 frameshifting efficiency of SARS-CoV-2 and other betacoronaviruses.
S0147	KKL-10	KKL-10 is an inhibitor of ribosome rescue that exhibits exceptional broad-spectrum antimicrobial activity against bacteria.
S4983	Sorbic acid	Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
S3710	Fosfomycin calcium	Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
S6031	2,6-Dihydroxybenzoic acid	2,6-Dihydroxybenzoic acid (γ-resorcylic acid, 2-Carboxyresorcinol, 2,6-Resorcylic acid) is a phenolic compound which is known to have poor biological performance such as DPPH scavenging activity and microbial growth inhibition.
S5166	Benzoyleneurea	Benzoyleneurea (2,4-Dihydroxyquinazoline, Quinazolinedione, Quinazoline-2,4-diol) scaffold is used in the synthesis of novel protein geranylgeranyltransferase-I inhibitors.
S6090	JFD01307SC	JFD01307SC ([(1,1-dioxidotetrahydrothien-3-yl)amino]acetic acid) shows activity against M.tuberculosis with minimum inhibitory concentrations (MICs) in the range of 8 to 16 µg/ml. JFD01307SC may targets enzymes involved in glutamine biosynthesis.
E4353^New	Ampicillin	Ampicillin (D-(-)-alpha-Aminobenzylpenicillin) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. It exhibits a good minimum inhibitory concentration for Staphylococcus aureus, Escherichia coli, Hemophilus influenzae, and Streptococcus pneumoniae with MICs of 0.6–1 mg/L, 4 mg/L, 0.25 mg/L, and 0.03-0.06 mg/L, respectively.
E0828	Mitonafide	Mitonafide inhibits the activity of Mycobacterium tuberculosis NAD+ dependent DNA ligase A at concentrations of 50 µM.
E0816	Oritavancin Diphosphate	Oritavancin Diphosphate is an orally active glycopeptide antibiotic which is active against Gram-positive bacteria and also has antibacterial activity against multidrug-resistant Streptococcus pneumoniae.
S4105	Closantel Sodium	Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
S4106	Closantel	Closantel (R-31520,nsc 335306) is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.	J Fungi (Basel), 2024, 10(2)131
S3712	Tulathromycin A	Tulathromycin A is a novel long-acting semi-synthetic tribasic macyocyclic antibiotic of the triamilide group and used for the treatment of pulmonary diseases of swine and cattle.
S0423	GSK2200150A	GSK2200150A is identified by high-throughput screening (HTS) campaign that can be used as an anti-tuberculosis (TB) agent (MIC = 0.38 µM).
E2952^New	2-Chloroacetamide	2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase.
S6464	Ftaxilide	Ftaxilide is a novel antituberculosis agent.
S0195	Walrycin B	Walrycin B is an antibacterial compound and a potent inhibitor of WalR targeting the WalR response regulator.
S4780	7-Methoxy-4-methylcoumarin	7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label.
S5201	Acetylisovaleryltylosin Tartrate	Acetylisovaleryltylosin tartrate (AK105039) is an antimicrobial of the macrolide group with antibacterial activity against Gram-positive bacteria.
S4544	Urethane	Urethane (Carbamic acid ethyl ester, Ethyl carbamate, Ethylurethane) is a kind of antineoplastic agent that is also used as a veterinary anesthetic. It is a intermediate in organic synthesis.	DSpace, 2023, Volume 30 Issue 11
S4425	Rifamycin S	Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation.
S4436	Pleuromutilin	Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
E0515	Cefatrizine	Cefatrizine, a broad-spectrum, semisynthetic, first-generation cephalosporin with antibacterial activity, binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
S7739	Telacebec	Telacebec is a novel antituberculosis drug that targets Mycobacterium tuberculosis cellular energy production through inhibition of the mycobacterial cytochrome bc1 complex. Telacebec (Q203, IAP6) is active against Mycobacterium tuberculosis H37Rv with MIC50 of 2.7 nM in culture broth medium.
S4404	Pasiniazid	Pasiniazid(Paraniazide,Pasiniazide) is a composition of isoniazid and 4-aminosalicylic acid, used to treat tuberculosis patients.
E2970^New	Gramicidin	Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is an antimicrobial peptide that destroys gram-positive bacteria. It inhibits the growth of bacteria by forming pores and channels in the cell wall, which increase its permeability to monovalent cations.
E4353^New	Ampicillin	Ampicillin (D-(-)-alpha-Aminobenzylpenicillin) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. It exhibits a good minimum inhibitory concentration for Staphylococcus aureus, Escherichia coli, Hemophilus influenzae, and Streptococcus pneumoniae with MICs of 0.6–1 mg/L, 4 mg/L, 0.25 mg/L, and 0.03-0.06 mg/L, respectively.
E2952^New	2-Chloroacetamide	2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase.

Bacterial阻害剤の選択性比較