Paclitaxel

For research use only. Not for use in humans.

製品コードS1150 別名:NSC 125973, PTX, Taxol, Onxal

Paclitaxel化学構造

CAS No. 33069-62-4

Paclitaxel (NSC 125973, PTX, Taxol, Onxal) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.

サイズ 価格(税別) 在庫  
10mM (1mL in DMSO) JPY 17100 あり
JPY 13600 あり
JPY 46800 あり
JPY 69700 あり
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バルク問合せ

文献中Selleckの製品使用例(206)

製品安全説明書

Antineoplastic and Immunosuppressive Antibiotics阻害剤の選択性比較

生物活性

製品説明 Paclitaxel (NSC 125973, PTX, Taxol, Onxal) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
ターゲット
Microtubule (human endothelial cells) [1]
0.1 pM
体外試験

Paclitaxel inhibits non-endothelial type human cells at 104 - to 105 -fold higher concentrations, with IC50 of 1 nM-10 nM. The selectivity of Paclitaxel inhibition of cell proliferation is also species specific, as mouse ECs are not sensitive to Paclitaxel at ultra low concentrations. Inhibition of human ECs by Paclitaxel at ultra low concentrations does not affect the cellular microtubule structure, and the treated cells do not show G2/M cell cycle arrest and apoptosis, suggesting a novel but as yet unidentified mechanism of action. In an in vitro angiogenesis assay, Paclitaxel at ultra low concentrations blocks human ECs from forming sprouts and tubes in the three-dimensional fibrin matrix. [1] In the presence of SMF, the efficient concentration of Paclitaxel on K562 cells is decreased from 50 to 10 ng/mL. The cell cycle arrest effect of Paclitaxel with or without SMF on K562 cells is correlated with DNA damage. [2] Paclitaxel alone causes a time-dependent inhibition of CDK1 in four cell lines including A549 cells, H358, H1395 cells and H1666 cells. [3]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
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NB14 NIDlfnVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW[4OpJMUUN3MDC9JFcvQDF|OTFOwG0> NIPuclQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
ES5 M{PwbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlTMTWM2OCB;IEeuPFY3PjJizszN NUH4W4NKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
SK-MEL-2 M2TMTGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkLrTWM2OCB;IEiuOFU6PzZizszN M1;kWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
COLO-800 M3jSTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXTuS4hvUUN3MDC9JFgvPDd6NzFOwG0> NV\yTmZORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
EB2 NHGwUJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWTqZmYzUUN3MDC9JFkvOTl6M{Wg{txO MmnsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
ES3 Mn;rS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVfYfW1qUUN3MDC9JFkvOzB4NkWg{txO NGPHS5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
SKM-1 M2[zUWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MlLQTWM2OCB;IEmuN|k1PTlizszN Mlv0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
MFM-223 NHHZfIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml\CTWM2OCB;IEmuOVAyOjdizszN MkTPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
LB2241-RCC NU\udFFtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MmSyTWM2OCB;IEGwMlA{QDZizszN MmPzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
EW-13 NEjkU4ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHnEPZRKSzVyIE2gNVAvOzN|MzFOwG0> MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
D-283MED M{DXd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NXzIV|ZkUUN3MDC9JFExNjR7NUmg{txO MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
EW-11 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{T3bmlEPTBiPTCxNU43Pjl2IN88US=> MkTPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
NCI-H128 MmfZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVfFbXViUUN3MDC9JFEzNjF|M{Sg{txO M1i0b|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
ES7 M1jDVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NE[3[FNKSzVyIE2gNVUvOjR7NDFOwG0> NVHYNFNERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
AM-38 MnvmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NV;KU4FvUUN3MDC9JFE2NjRzNk[g{txO MnXDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
NCI-H716 MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml3qTWM2OCB;IEG3MlkzQTlizszN Mn;hQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
NCI-H1770 NXnWXXYxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV7hVZRJUUN3MDC9JFE5NjN6NUGg{txO MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
JVM-3 MkTNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmKyTWM2OCB;IEKwMlg6QDVizszN NWK4UXJXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
CW-2 NIK2cpBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NF7TZ4RKSzVyIE2gNlEvOTN2OTFOwG0> NXzPTldZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
YT NF\PZ4VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mlj2TWM2OCB;IEKxMlQ3QTFizszN Ml\QQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
C8166 NVLKdZVsT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NX\k[XN7UUN3MDC9JFIzNjJ5NE[g{txO NGXPV3g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
SUP-T1 NYTq[JgxT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4njb2lEPTBiPTCyN{4zPTF{IN88US=> M1rQfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
KASUMI-1 MnfHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MoLOTWM2OCB;IEKzMlUyOTlizszN NYWwfnFbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
IM-9 NEjPS4FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGrLd|VKSzVyIE2gNlMvPjl5OTFOwG0> NWX0RYl5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
NH-12 M2fLRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NVL6OHE2UUN3MDC9JFI1NjF4NUSg{txO M3nUPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
WSU-NHL NYnZb2drT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnroTWM2OCB;IEK1MlczPjFizszN NITBfGQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
TUR NVv2NHl7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3LuVmlEPTBiPTCyOk43PTN|IN88US=> Mk\ZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
RL M3jnNmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIrRPVdKSzVyIE2gNlcvOjJ2MjFOwG0> NFS2bJI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
EW-12 NUD3Z5luT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV\WdYdHUUN3MDC9JFI5NjB5MEKg{txO NV6zNnJRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
KG-1 NYfSOm02T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NV7ESmNiUUN3MDC9JFI5NjJ6NkWg{txO NIX3OJg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
P31-FUJ MlnhS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEfadYdKSzVyIE2gNlkvODR6OTFOwG0> M1Hud|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
NB10 M3y1PGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2DCPGlEPTBiPTCzNU42ODlizszN MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
COLO205 MVfDfZRwfG:6aXPpeJkh[XO|YYm= M4jCc2dKPTBiPTCwMlAxOTd4IN88US=> MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek84QTB6OUWwK|44QTB6OUWwQE9iRg>?
SF539 MX\DfZRwfG:6aXPpeJkh[XO|YYm= Mm[yS2k2OCB;IECuNFA{PjZizszN NEPNWFI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95OUC4PVUxLz55OUC4PVUxRC:jPh?=
SNB75 MUXDfZRwfG:6aXPpeJkh[XO|YYm= NIXaRoVIUTVyIE2gNE4xODhyODFOwG0> NFq2R5Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95OUC4PVUxLz55OUC4PVUxRC:jPh?=
DMS114 MXvDfZRwfG:6aXPpeJkh[XO|YYm= NF7OboZIUTVyIE2gNE4xOTJ|IN88US=> M2fDNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzd7MEi5OVAoRjd7MEi5OVA9N2F-
OVCAR-3 M2XWUWN6fG:2b4jpZ4l1gSCjc4PhfS=> NVLmVHp7T0l3MDC9JFAvODF7NzFOwG0> Ml23QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzlyOEm1NEc,PzlyOEm1NFww[T5?
NCI-H460 MU\DfZRwfG:6aXPpeJkh[XO|YYm= NH;4UGpIUTVyIE2gNE4xOjF7IN88US=> MmLCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzlyOEm1NEc,PzlyOEm1NFww[T5?
HOP62 NVvqSHZWS3m2b4TvfIlkcXS7IHHzd4F6 M1W5TmdKPTBiPTCwMlA3PzFizszN M1rKXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzd7MEi5OVAoRjd7MEi5OVA9N2F-
mammary carcinoma NX\KUYtTS3m2b4TvfIlkcXS7IHHzd4F6 NHHWRnVKSzVyIE2gNE4zQTlizszN NHqye4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi96MUiyOlk5Lz56MUiyOlk5RC:jPh?=
NCI60 MnP5R5l1d3SxeHnjbZR6KGG|c3H5 MVfHTVUxKD1iMD6wNFA3PSEQvF2= MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek86PDZzNkWzK|46PDZzNkWzQE9iRg>?
MCF-7 MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYXHTVUxKD1iMD6wNFEyKM7:TR?= NYPnbphxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOUi3N|U6Pyd-OUi3N|U6PzxxYU6=
murine leukemic P388 MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml\TS2k2OCB;IECuNFE3KM7:TR?= NEXiSmQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi97OEezOVk4Lz57OEezOVk4RC:jPh?=
KB MmLqR5l1d3SxeHnjbZR6KGG|c3H5 MWPJR|UxKD1iMD6wNFYh|ryP MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yODl5OEKwNEc,OTB7N{iyNFA9N2F-
MCF7 M3zLVGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MVG3NkBp MoS3TWM2OCB;IECuNFAzKM7:TR?= NIfLV5I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUOyOVIzPid-MUGzNlUzOjZ:L3G+
MCF-7 MoDXR5l1d3SxeHnjbZR6KGG|c3H5 MmCxSWQ2OCB;IECuNFA1KM7:TR?= M4H1[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzM{O0OVY4Lz5zMUOzOFU3PzxxYU6=
uterine sarcoma (MES-SA) NF\TWFNEgXSxdH;4bYNqfHliYYPzZZk> MWHJR|UxKD1iMD6wNFAxPCEQvF2= MoTtQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF5MkixPVEoRjFzN{K4NVkyRC:jPh?=
nonsmall cell lung carcinoma (NCI-H460) NED1W4pEgXSxdH;4bYNqfHliYYPzZZk> Ml33TWM2OCB;IECuNFAxOTRizszN NXfjVY5xRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUG3NlgyQTFpPkGxO|I5OTlzPD;hQi=>
colon adenocarcinoma (HT-29) MnzjR5l1d3SxeHnjbZR6KGG|c3H5 MoXUTWM2OCB;IECuNFAxOTZizszN NIrCNY09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUeyPFE6OSd-MUG3NlgyQTF:L3G+
prostate carcinoma (DU-145) MUjDfZRwfG:6aXPpeJkh[XO|YYm= MlrFTWM2OCB;IECuNFA1QDlizszN NFvtdXE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUeyPFE6OSd-MUG3NlgyQTF:L3G+
SW626 MoPLR5l1d3SxeHnjbZR6KGG|c3H5 MnLOO|IhcA>? MYjJR|UxKD1iMD6wNFAxOSEQvF2= NYrwcldORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKwPFg1OjVpPkGyNFg5PDJ3PD;hQi=>
Lu1 M1nlUWN6fG:2b4jpZ4l1gSCjc4PhfS=> NUDxfXY4PzJiaB?= M3H6PWlEPTBiPTCwMlAyKM7:TR?= NFzEWGI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkC4PFQzPSd-MUKwPFg1OjV:L3G+
MCF7 MlS5R5l1d3SxeHnjbZR6KGG|c3H5 NFH1SGI4OiCq Mn;STWM2OCB;IECuNFIh|ryP MnzxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJyOEi0NlUoRjF{MEi4OFI2RC:jPh?=
P388 MojhR5l1d3SxeHnjbZR6KGG|c3H5 MnzvO|IhcA>? MXXJR|UxKD1iMD6wNkDPxE1? MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjB6OESyOUc,OTJyOEi0NlU9N2F-
LNCAP M4TGXGN6fG:2b4jpZ4l1gSCjc4PhfS=> NIWzRZI4OiCq MmHXTWM2OCB;IECuNFIh|ryP MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjB6OESyOUc,OTJyOEi0NlU9N2F-
KB NHXFTWREgXSxdH;4bYNqfHliYYPzZZk> MnXlO|IhcA>? MmTsTWM2OCB;IECuNFIh|ryP MmTTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJyOEi0NlUoRjF{MEi4OFI2RC:jPh?=
Col2 NXfmOIRwS3m2b4TvfIlkcXS7IHHzd4F6 NWHl[3lYPzJiaB?= NWq1VWx5UUN3MDC9JFAvODJizszN NHz3eFk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkC4PFQzPSd-MUKwPFg1OjV:L3G+
BC1 MXnDfZRwfG:6aXPpeJkh[XO|YYm= M1LD[FczKGh? NWnnRZlZUUN3MDC9JFAvODJizszN M2\WOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MEi4OFI2Lz5zMkC4PFQzPTxxYU6=
SK-MEL-2 NU\2NIFtS3m2b4TvfIlkcXS7IHHzd4F6 Ml;KO|IhcA>? MXPJR|UxKD1iMD6wO{DPxE1? M4PBcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MEi4OFI2Lz5zMkC4PFQzPTxxYU6=
L2987 MVHDfZRwfG:6aXPpeJkh[XO|YYm= MoW1TWM2OCB;IECuNkDPxE1? Mk\6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJ2NEO3PFMoRjF{NESzO|g{RC:jPh?=
colon adenocarcinoma RKO Mn\2R5l1d3SxeHnjbZR6KGG|c3H5 NX;rWY5zUUN3MDC9JFAvODFizszN M1HFe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{OEWyO|Y5Lz5zMki1Nlc3QDxxYU6=
NCI-H460 M2DJc2N6fG:2b4jpZ4l1gSCjc4PhfS=> MmrQOFghcA>? NUPkbnluUUN3MDC9JFAvODB7NTFOwG0> NF3OTo89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNE[5OVc6QCd-MUS2PVU4QTh:L3G+
MCF7 M1SyVmN6fG:2b4jpZ4l1gSCjc4PhfS=> MoPkOFghcA>? MmfxTWM2OCB;IECuNFEyOiEQvF2= NUnwenpmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUS2PVU4QThpPkG0Olk2Pzl6PD;hQi=>
SF268 MVHDfZRwfG:6aXPpeJkh[XO|YYm= NIjQUWY1QCCq M{Xub2lEPTBiPTCwMlAzOTdizszN M3KzPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF2Nkm1O|k5Lz5zNE[5OVc6QDxxYU6=
MDA-MB-231 MkjVR5l1d3SxeHnjbZR6KGG|c3H5 NH7vflE1QCCq Mk\sTWM2OCB;IECuNFA1PSEQvF2= NFrIZm49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEm4O|A2OSd-MUS5PFcxPTF:L3G+
MCF7 M{\0eWN6fG:2b4jpZ4l1gSCjc4PhfS=> MljIOFghcA>? M12ySWlEPTBiPTCwMlAxPDlizszN MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDl6N{C1NUc,OTR7OEewOVE9N2F-
A2780 M1zRdGN6fG:2b4jpZ4l1gSCjc4PhfS=> M4K5ZVQ5KGh? NVe5XHE6UUN3MDC9JFAvODJ3IN88US=> MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDl6N{C1NUc,OTR7OEewOVE9N2F-
PC3 MkDjR5l1d3SxeHnjbZR6KGG|c3H5 MmDVOFghcA>? NEPwW3BKSzVyIE2gNE4xPzdizszN MkCzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR7OEewOVEoRjF2OUi3NFUyRC:jPh?=
MCF7 NY\vToxES3m2b4TvfIlkcXS7IHHzd4F6 NGrjO3o4OiCq MX3JR|UxKD1iMD6wNFE1KM7:TR?= MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDl6N{C1Okc,OTR7OEewOVY9N2F-
multidrug-resistant MCF7 NUHuSZRkS3m2b4TvfIlkcXS7IHHzd4F6 NHm4dHQ4OiCq NEfnNI9KSzVyIE2gNE4{PTRizszN M1;ue|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF2OUi3NFU3Lz5zNEm4O|A2PjxxYU6=
PC3 MYnDfZRwfG:6aXPpeJkh[XO|YYm= NGnndYU1QCCq NV;RN5RiUUN3MDC9JFAvODF4IN88US=> MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwNkc,OTVyNEO0NFI9N2F-
Hep3B NVvIXWl[S3m2b4TvfIlkcXS7IHHzd4F6 M2XyUlQ5KGh? MnHBTWM2OCB;IECuNFMyKM7:TR?= NXHBTINDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODJpPkG1NFQ{PDB{PD;hQi=>
NCI-H460 MnrhR5l1d3SxeHnjbZR6KGG|c3H5 MkDJOFghcA>? MU\JR|UxKD1iMD6wNFk2KM7:TR?= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwOEc,OTVyNEO0NFQ9N2F-
MCF7 NEfaRmhEgXSxdH;4bYNqfHliYYPzZZk> NHrZdHU1QCCq MoXyTWM2OCB;IECuNFEyOiEQvF2= MonSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTVyNEO0NFQoRjF3MESzOFA1RC:jPh?=
SF268 MVLDfZRwfG:6aXPpeJkh[XO|YYm= MmTKOFghcA>? NWnsPFhbUUN3MDC9JFAvODJzNzFOwG0> MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwOEc,OTVyNEO0NFQ9N2F-
KB M3:wSWN6fG:2b4jpZ4l1gSCjc4PhfS=> M3vFdWVFPTBiPTCwMlAxODRizszN NG\3XIw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUC0N|QxPyd-MUWwOFM1ODd:L3G+
Lu1 MnnFR5l1d3SxeHnjbZR6KGG|c3H5 NIHWZmJGTDVyIE2gNE4xODJizszN NF3kd2Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUC0N|QxPyd-MUWwOFM1ODd:L3G+
LNCAP NIXIfG5EgXSxdH;4bYNqfHliYYPzZZk> M1LXNWVFPTBiPTCwMlAxPSEQvF2= NUXmRWRxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODdpPkG1NFQ{PDB5PD;hQi=>
RPE1 NHnK[IJEgXSxdH;4bYNqfHliYYPzZZk> NF75PHhGTDVyIE2gNE4xOjNizszN M3v6WlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3MESzOFA4Lz5zNUC0N|QxPzxxYU6=
Col2 NYj0[|NxS3m2b4TvfIlkcXS7IHHzd4F6 NIqxfGVGTDVyIE2gNE4xPDZizszN M3HvOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3MESzOFA4Lz5zNUC0N|QxPzxxYU6=
T47D MV3BdI9xfG:|aYOgZZN{[Xl? MXqyOEBp NUHUPW1tTUN3MDC9JFAvODNizszN NHW3fWU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUW2OlMxOCd-MUW1OlY{ODB:L3G+
DLD1 M{LEOWFxd3C2b4Ppd{Bie3OjeR?= Mnr3NlQhcA>? MWTFR|UxKD1iMD6wO|Uh|ryP MkfPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV3Nk[zNFAoRjF3NU[2N|AxRC:jPh?=
H1299 NFXib5FCeG:ydH;zbZMh[XO|YYm= NYXDW5ltOjRiaB?= NXTndIRxTUN3MDC9JFAvOTZ|IN88US=> M3HnT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3NU[2N|AxLz5zNUW2OlMxODxxYU6=
VA13 M1P1[WN6fG:2b4jpZ4l1gSCjc4PhfS=> MmHPOFghcA>? NXz4VXhRUUN3MDC9JFAvODB3IN88US=> M17xZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{OwNlQ{Lz5zNUezNFI1OzxxYU6=
WI 38 MlH0R5l1d3SxeHnjbZR6KGG|c3H5 MVq0PEBp MlrXTWM2OCB;IECuNFQh|ryP M4robFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{OwNlQ{Lz5zNUezNFI1OzxxYU6=
Hep G2 MYrDfZRwfG:6aXPpeJkh[XO|YYm= M4PXV|Q5KGh? M{ntbWlEPTBiPTC4MlEh|ryP NWPNW5o6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3N|AzPDNpPkG1O|MxOjR|PD;hQi=>
A549 M4XnOGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWfNZmw4PDhiaB?= M1jtWWlEPTBiPTCxMlI2KM7:TR?= MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd6N{S2NEc,OTV5OEe0OlA9N2F-
SKOV3 M3nKXWN6fG:2b4jpZ4l1gSCjc4PhfS=> NUjzWmJrPDhiaB?= MlztTWM2OCB;IEGuN|Uh|ryP MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd6N{S2NEc,OTV5OEe0OlA9N2F-
KB MoTOR5l1d3SxeHnjbZR6KGG|c3H5 NGLUfo4{KGSjeYO= MWPJR|UxKD1iMD6wNFEh|ryP Mn7lQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZyM{i1OFUoRjF4MEO4OVQ2RC:jPh?=
1A9 NVG1XGNiS3m2b4TvfIlkcXS7IHHzd4F6 M2HTSFMh\GG7cx?= MUjJR|UxKD1iMD6wNFIh|ryP MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjB|OEW0OUc,OTZyM{i1OFU9N2F-
HCT8 MonjR5l1d3SxeHnjbZR6KGG|c3H5 NH7uTGw{KGSjeYO= M2HkOGlEPTBiPTCwMlAyOyEQvF2= M3fkT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4MEO4OVQ2Lz5zNkCzPFU1PTxxYU6=
A431 NGfCUIhE\WyuIHP5Z4xmKGG{cnXzeEBie3OjeR?= MWXFR|UxKD1iMD6wNFkh|ryP MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjN5N{G4O{c,OTZ|N{exPFc9N2F-
VA13 M1Xrc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV3SUotyPDhiaB?= Ml[5TWM2OCB;IECuNFA1OyEQvF2= MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjR7OUOyNkc,OTZ2OUmzNlI9N2F-
WI38 NGSxW|BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV[0PEBp NVqzWpUyUUN3MDC9JFAvODN2IN88US=> MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjR7OUOyNkc,OTZ2OUmzNlI9N2F-
HepG2 NYjjdodPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmjxOFghcA>? MXjJR|UxKD1iNj65JO69VQ>? NInGS4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkS5PVMzOid-MU[0PVk{OjJ:L3G+
Aro Ml7CR5l1d3SxeHnjbZR6KGG|c3H5 MYXJR|UxKD1iMD6wNFAzKM7:TR?= MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV|OUO3O{c,OTZ3M{mzO|c9N2F-
PT45 M33FcGN6fG:2b4jpZ4l1gSCjc4PhfS=> Mn3JTWM2OCB;IECuNFA2KM7:TR?= NEHoNYg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
A549 MnjsR5l1d3SxeHnjbZR6KGG|c3H5 M2DucmlEPTBiPTCwMlAxPiEQvF2= NWPrVIpURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
MCF7 NGrkb41EgXSxdH;4bYNqfHliYYPzZZk> NWjje3ZyUUN3MDC9JFAvODB5IN88US=> NFfRclI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
HeLa MVHDfZRwfG:6aXPpeJkh[XO|YYm= NXn1fJlEUUN3MDC9JFAvODB6IN88US=> MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV|OUO3O{c,OTZ3M{mzO|c9N2F-
Ovcar3 MV\DfZRwfG:6aXPpeJkh[XO|YYm= MoLHTWM2OCB;IECuNFEh|ryP MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV|OUO3O{c,OTZ3M{mzO|c9N2F-
HT29 MoPRR5l1d3SxeHnjbZR6KGG|c3H5 NF\kb3lKSzVyIE2gNE4xPSEQvF2= NVHoSpVHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
H295R M1jIVmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVLweJhqUUN3MDC9JFAvODhizszN MkOzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
BNL NHLsdXZEgXSxdH;4bYNqfHliYYPzZZk> M1K2TmlEPTBiPTCwMlIh|ryP M3rzeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
4T1 NWHiUI1{S3m2b4TvfIlkcXS7IHHzd4F6 NWHWN|NXUUN3MDC9JFAvOiEQvF2= NWnOWotrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
HepG2 M3\mdGN6fG:2b4jpZ4l1gSCjc4PhfS=> MV7JR|UxKD1iMD6zJO69VQ>? NIC0N449[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
U937 GTB MYPDfZRwfG:6aXPpeJkh[XO|YYm= M1nB[|czKGh? NHfSNG9KSzVyIE2gNE4xODV7IN88US=> NEKxelQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkW2Nlg1OCd-MU[1OlI5PDB:L3G+
RPMI 8226/s NFS5N|ZEgXSxdH;4bYNqfHliYYPzZZk> M13nflczKGh? MUfJR|UxKD1iMD6wNFch|ryP MnvkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3NkK4OFAoRjF4NU[yPFQxRC:jPh?=
CEM/s NVnI[mdDS3m2b4TvfIlkcXS7IHHzd4F6 NVXJUHJiPzJiaB?= M1\mXGlEPTBiPTCwMlAxPyEQvF2= NXrZWWxiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1OlI5PDBpPkG2OVYzQDRyPD;hQi=>
VA13 NYDz[Hk6S3m2b4TvfIlkcXS7IHHzd4F6 MWLJR|UxKD1iMD6wNFU6KM7:TR?= NGrRTVI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkeyOFg1Oid-MU[3NlQ5PDJ:L3G+
WI38 MlPaR5l1d3SxeHnjbZR6KGG|c3H5 MkjHTWM2OCB;IECuNFQ3QCEQvF2= NG\3THU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkeyOFg1Oid-MU[3NlQ5PDJ:L3G+
HepG2 MYDDfZRwfG:6aXPpeJkh[XO|YYm= NVmydFE4UUN3MDC9JFkvPDlizszN NXPJSFFuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[3NlQ5PDJpPkG2O|I1QDR{PD;hQi=>
HT29 MV\DfZRwfG:6aXPpeJkh[XO|YYm= NV\pTXJUTUN3MDC9JFAvODB4IN88US=> MkTwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ6N{C0NlgoRjF4OEewOFI5RC:jPh?=
K562 NX3IT2NRS3m2b4TvfIlkcXS7IHHzd4F6 MkXxSWM2OCB;IECuNFE1KM7:TR?= MmDOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ6N{C0NlgoRjF4OEewOFI5RC:jPh?=
MCF7 MWTDfZRwfG:6aXPpeJkh[XO|YYm= NEjBW3hGSzVyIE2gNE4xOzZizszN M2XkdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4OEewOFI5Lz5zNki3NFQzQDxxYU6=
VA-13 NWfvTIN2S3m2b4TvfIlkcXS7IHHzd4F6 NWn5fFN1UUN3MDC9JFAvODB3IN88US=> NXi1SnhERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[5N|M5PjhpPkG2PVM{QDZ6PD;hQi=>
WI38 M3v2VGN6fG:2b4jpZ4l1gSCjc4PhfS=> M2fPdmlEPTBiPTCwMlA1KM7:TR?= MoHSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ7M{O4OlgoRjF4OUOzPFY5RC:jPh?=
VA13 NH;1Z41EgXSxdH;4bYNqfHliYYPzZZk> MmP6TWM2OCB;IECuNFA2KM7:TR?= NF\BN5M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{C2O|E2PSd-MUewOlcyPTV:L3G+
WI38 M3fyfGN6fG:2b4jpZ4l1gSCjc4PhfS=> MXXJR|UxKD1iMD6wOEDPxE1? M1vKZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5ME[3NVU2Lz5zN{C2O|E2PTxxYU6=
Hep G2 M{W1XWN6fG:2b4jpZ4l1gSCjc4PhfS=> MljiTWM2OCB;IEiuNUDPxE1? MlPHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdyNkexOVUoRjF5ME[3NVU2RC:jPh?=
TW01 NXnzU|VUS3m2b4TvfIlkcXS7IHHzd4F6 M3fxTmlEPTBiPTCwMlAxODNizszN MmC3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzMUOyPFgoRjF5MUGzNlg5RC:jPh?=
MCF7 NEjK[GdEgXSxdH;4bYNqfHliYYPzZZk> MXfJR|UxKD1iMD6wNFA2KM7:TR?= MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzFzM{K4PEc,OTdzMUOyPFg9N2F-
MKN45 NEC2[odEgXSxdH;4bYNqfHliYYPzZZk> NH\iU|dKSzVyIE2gNE4xODB3IN88US=> Ml7iQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzMUOyPFgoRjF5MUGzNlg5RC:jPh?=
MES-SA NVv2VnRJS3m2b4TvfIlkcXS7IHHzd4F6 NGfVdWFKSzVyIE2gNE4xODB3IN88US=> M{Xhb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
HCT116 MUXDfZRwfG:6aXPpeJkh[XO|YYm= NVHJRmpoUUN3MDC9JFAvODByNjFOwG0> NUnhfIRpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexNVMzQDhpPkG3NVE{Ojh6PD;hQi=>
RPTEC NH7seIpEgXSxdH;4bYNqfHliYYPzZZk> NXTIU|hzUUN3MDC9JFAvODByOTFOwG0> MlSwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzMUOyPFgoRjF5MUGzNlg5RC:jPh?=
Hep3B MW\DfZRwfG:6aXPpeJkh[XO|YYm= MXfJR|UxKD1iMD6wNFU1KM7:TR?= NWnNSpV2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexNVMzQDhpPkG3NVE{Ojh6PD;hQi=>
NCI-H226 NE\CXI9EgXSxdH;4bYNqfHliYYPzZZk> NFzUOJZKSzVyIE2gNE4xODZ6IN88US=> NY\yeFRERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexNVMzQDhpPkG3NVE{Ojh6PD;hQi=>
A498 MnKzR5l1d3SxeHnjbZR6KGG|c3H5 MlrwTWM2OCB;IECuNFYyKM7:TR?= NIHDZog9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{GxN|I5QCd-MUexNVMzQDh:L3G+
MDA435/LCC6 NYLtWWRsSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NEHTcolKSzVyIE2gNE4xODJ7IN88US=> MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF3NEWwOUc,OTdzNUS1NFU9N2F-
multidrug resistant MDA435/LCC6 MYDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NITFPI5KSzVyIE2gNE4xODR6IN88US=> M1HEUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUW0OVA2Lz5zN{G1OFUxPTxxYU6=
P388 NUm0RYM6SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NHLYVWtKSzVyIE2gNE4xOjJizszN M1PBZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUW0OVA2Lz5zN{G1OFUxPTxxYU6=
adriamycin resistant P388 MmTYRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MYjJR|UxKD1iMD6wN{DPxE1? NFTDW2Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G1OFUxPSd-MUexOVQ2ODV:L3G+
LT12 M3HF[mFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MkmyOFghcA>? NW[5U3NoUUN3MDC9JFAvODB4IN88US=> NVXpXlFpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
SKOV3 NGDkTZJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MkPXOFghcA>? MnLkTWM2OCB;IECuNFEh|ryP NXzNPVRRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
NCI-H460 M1XLemFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NX;SU3lkPDhiaB?= MVLJR|UxKD1iMD6wNUDPxE1? M2njdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUixNVY1Lz5zN{G4NVE3PDxxYU6=
SF268 NHi2WGZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MkLEOFghcA>? NF;GT4tKSzVyIE2gNE4xOSEQvF2= NYrGeY9yRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
RKO M1rqV2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NYLD[mpIPDhiaB?= MkHhTWM2OCB;IECuNFEh|ryP MkizQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzOEGxOlQoRjF5MUixNVY1RC:jPh?=
KB/HeLa MlH4RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NYTxPG95PDhiaB?= NFLZS21KSzVyIE2gNE4xOSEQvF2= NV;kSFJORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
P388 MX\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NXz4UWZXPDhiaB?= NH7DfYpKSzVyIE2gNE4xPCEQvF2= NGDJUJE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G4NVE3PCd-MUexPFEyPjR:L3G+
L1210 MXnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MmDpOFghcA>? M3;3TWlEPTBiPTCwMlA3KM7:TR?= NUH2cnFRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
LT12 MDR MYLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NHrMbIU1QCCq NVjm[It5UUN3MDC9JFAvPCEQvF2= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
A2780 NWXC[nQ2S3m2b4TvfIlkcXS7IHHzd4F6 MWHJR|UxKD1iMD6wNFEh|ryP MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzJyNkGzPUc,OTd{ME[xN|k9N2F-
A2780-1A9 NVXj[IdnS3m2b4TvfIlkcXS7IHHzd4F6 NVWyNGVOUUN3MDC9JFAvODBzMTFOwG0> M{W4TVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkC2NVM6Lz5zN{KwOlE{QTxxYU6=
A549 M2DRbWN6fG:2b4jpZ4l1gSCjc4PhfS=> NFK0[nVKSzVyIE2gNE4xODN4IN88US=> MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzJyNkGzPUc,OTd{ME[xN|k9N2F-
1A9PTX22 NFHrT|dEgXSxdH;4bYNqfHliYYPzZZk> NFzCXWdKSzVyIE2gNE4xOTlizszN M1[4U|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkC2NVM6Lz5zN{KwOlE{QTxxYU6=
1A9PTX10 MofWR5l1d3SxeHnjbZR6KGG|c3H5 NWjyWo1RUUN3MDC9JFAvODNizszN NUnjZlRjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyNFYyOzlpPkG3NlA3OTN7PD;hQi=>
A2780AD NYnhcG0yS3m2b4TvfIlkcXS7IHHzd4F6 Mn:2TWM2OCB;IECuPUDPxE1? MmPoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{ME[xN|koRjF5MkC2NVM6RC:jPh?=
KB M2rPV2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MWjJR|UxKD1iMD6wNFI1PSEQvF2= Ml;lQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{Mki4O|MoRjF5MkK4PFc{RC:jPh?=
COLO205 NH[4R2lEgXSxdH;4bYNqfHliYYPzZZk> MlWwTWM2OCB;IECuNFA{OyEQvF2= NIH6RXE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KyPFg4Oyd-MUeyNlg5PzN:L3G+
KB8.5 MXjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NFLBZ2dKSzVyIE2gNE4xOjZizszN NYXxUGVIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyNlg5PzNpPkG3NlI5QDd|PD;hQi=>
KBV1 M1faeGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NYfLdZBWUUN3MDC9JFIvODF|IN88US=> NEXHW5U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KyPFg4Oyd-MUeyNlg5PzN:L3G+
A2780 MYHDfZRwfG:6aXPpeJkh[XO|YYm= NGD0OnNKSzVyIE2gNE4xODB5IN88US=> NUmxW5NuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyN|k2QTdpPkG3NlM6PTl5PD;hQi=>
2780AD M{jGSGN6fG:2b4jpZ4l1gSCjc4PhfS=> M1jWeGlEPTBiPTCwMlU{PSEQvF2= MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzJ|OUW5O{c,OTd{M{m1PVc9N2F-
1A9 NInsNI5EgXSxdH;4bYNqfHliYYPzZZk> NIf2VHNGTDVyIE2gNE4xODFizszN NUTrZnpbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
MCF7 MXvDfZRwfG:6aXPpeJkh[XO|YYm= NHPWXINGTDVyIE2gNE4xODFzIN88US=> M2Dm[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
DU145 MoTtR5l1d3SxeHnjbZR6KGG|c3H5 NHLWb|lGTDVyIE2gNE4xODF|IN88US=> NYXMSZlDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
KB MUTDfZRwfG:6aXPpeJkh[XO|YYm= MlewSWQ2OCB;IECuNFAyQCEQvF2= MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzN3MEizOEc,OTd|NUC4N|Q9N2F-
A549 NGfmRXJEgXSxdH;4bYNqfHliYYPzZZk> NXewd4trTUR3MDC9JFAvODB{MzFOwG0> NVPyR3NqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
LNCAP MULDfZRwfG:6aXPpeJkh[XO|YYm= Mmn6SWQ2OCB;IECuNFAzPiEQvF2= NVHNPFJxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
PC3 NF;zblhEgXSxdH;4bYNqfHliYYPzZZk> M3jTOGVFPTBiPTCwMlA2PTVizszN NV3RPHplRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
KBVIN M2DkNGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWfwSm9TTUR3MDC9JFAvOzFzIN88US=> M2nrSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
A2780 MXvDfZRwfG:6aXPpeJkh[XO|YYm= NHX1RoVKSzVyIE2gNE4xODF4IN88US=> NXr3Z3YxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezPVU1PjVpPkG3N|k2PDZ3PD;hQi=>
A2780/AD NI\yR5NEgXSxdH;4bYNqfHliYYPzZZk> NVTKV|hEUUN3MDC9JFAvQTJizszN NVnK[JFURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezPVU1PjVpPkG3N|k2PDZ3PD;hQi=>
KB NXviTmJ{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MYnJR|UxKD1iMD6wNFI1PSEQvF2= MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzRzNkWyOEc,OTd2MU[1NlQ9N2F-
COLO205 NUDLRmYxS3m2b4TvfIlkcXS7IHHzd4F6 NWHlempQUUN3MDC9JFAvODB|MzFOwG0> MnzyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MU[1NlQoRjF5NEG2OVI1RC:jPh?=
KB8.5 NHix[XBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MlfjTWM2OCB;IECuNFI3KM7:TR?= NUXUVlAzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVY2OjRpPkG3OFE3PTJ2PD;hQi=>
KBV1 M4Lp[WFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NUTqR4pJUUN3MDC9JFIvODF|IN88US=> Mk\TQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MU[1NlQoRjF5NEG2OVI1RC:jPh?=
neural precursor M1HkdGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MX7FR|UxKD1iMD6wNUDPxE1? M1XrTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG3OlMyLz5zN{SxO|Y{OTxxYU6=
OVCAR-3 NIHCW29EgXSxdH;4bYNqfHliYYPzZZk> NUnHSYZiUUN3MDC9JFAvODByMjFOwG0> M{nDb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
MDA-MB-231 MV;DfZRwfG:6aXPpeJkh[XO|YYm= NFjhNZJKSzVyIE2gNE4xODR3IN88US=> NEDMV4E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxPVA3PSd-MUe0NVkxPjV:L3G+
MCF7 MVvDfZRwfG:6aXPpeJkh[XO|YYm= MVzJR|UxKD1iMD6wNFQ6KM7:TR?= M2m0SlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
NCI-H1299 MXTDfZRwfG:6aXPpeJkh[XO|YYm= MoXTPVYhcA>? NYTUOIFQUUN3MDC9JFAvODF3IN88US=> M4fkelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
A2780 MX\DfZRwfG:6aXPpeJkh[XO|YYm= NV3GbmdTUUN3MDC9JFAvODJ3IN88US=> M3riTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
PC3 NVrvV|Q{S3m2b4TvfIlkcXS7IHHzd4F6 MX7JR|UxKD1iMD6wO|ch|ryP NVThV2ZMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVkxPjVpPkG3OFE6ODZ3PD;hQi=>
LoVo NGn5UlBEgXSxdH;4bYNqfHliYYPzZZk> MX3JR|UxKD1iMD6wPUDPxE1? NULSfXVTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVkxPjVpPkG3OFE6ODZ3PD;hQi=>
L2987 MmmwR5l1d3SxeHnjbZR6KGG|c3H5 M2LSXGlEPTBiPTCwMlIh|ryP Mn\pQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MUmwOlUoRjF5NEG5NFY2RC:jPh?=
cells NUXjVGgyS3m2b4TvfIlkcXS7IHHzd4F6 NYjaSm1HUUN3MDC9JFAvODB3OTFOwG0> NUnzTGVXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFI2PzdpPkG3OFQzPTd5PD;hQi=>
cells M1T3S2N6fG:2b4jpZ4l1gSCjc4PhfS=> NWfxe4xCUUN3MDC9JFAvODFizszN MoXhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OEWyNFcoRjF5NEi1NlA4RC:jPh?=
A2780 NEWwbWZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVjJR|UxKD1iMD6wNFI5KM7:TR?= MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR7MEi3PEc,OTd2OUC4O|g9N2F-
VA13 MkHZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NF7QN29KSzVyIE2gNE4xODVizszN M4jITFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEmwPFc5Lz5zN{S5NFg4QDxxYU6=
WI38 NETa[GZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmjzTWM2OCB;IECuNFQh|ryP NH[1[pk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S5NFg4QCd-MUe0PVA5Pzh:L3G+
2780AD Ml;kS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmOzTWM2OCB;IECuNVg{KM7:TR?= MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR7MEi3PEc,OTd2OUC4O|g9N2F-
HepG2 M4nGWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NU\L[mVbUUN3MDC9JFgvOSEQvF2= M2fDU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEmwPFc5Lz5zN{S5NFg4QDxxYU6=
HT29 M3rUeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlvpOFghcA>? Ml3qS2k2OCB;IECuNFE2KM7:TR?= MlLzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUi5OlAoRjF5NEm4PVYxRC:jPh?=
M21 MmnrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M37pR|Q5KGh? MkPVS2k2OCB;IECuNFM4KM7:TR?= MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR7OEm2NEc,OTd2OUi5OlA9N2F-
MCF7 MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoLrOFghcA>? NX\rUWJzT0l3MDC9JFAvODV2IN88US=> MorIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUi5OlAoRjF5NEm4PVYxRC:jPh?=
1A9 NH7FTo1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{HpTVczKGh? MnHZS2k2OCB;IECuNFAxPzFizszN Ml3rQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEK1O|IoRjF5NUSyOVczRC:jPh?=
1A9/Ptx22 MmXPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEDGVXA4OiCq Mn7PS2k2OCB;IECuNFUyKM7:TR?= NWLOXHpFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1OFI2PzJpPkG3OVQzPTd{PD;hQi=>
1A9/Ptx10 MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYG3NkBp M4WxNmdKPTBiPTCwMlA3PCEQvF2= Ml;nQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEK1O|IoRjF5NUSyOVczRC:jPh?=
cells expressing MRP1 NHq1XYxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnzvTWM2OCB;IECuNFAzPSEQvF2= NEfkS|k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W2O|EzOSd-MUe1OlcyOjF:L3G+
cells expressing Pgp/MRP1 NV7kb4VJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3zHcGlEPTBiPTCyMlch|ryP M4XudlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NU[3NVIyLz5zN{W2O|EzOTxxYU6=
VA13 M2LGd2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NY\NU21GUUN3MDC9JFUh|ryP Mm\FQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3OUWxN|QoRjF5NUm1NVM1RC:jPh?=
MCF7 M2fiWmZ2dmO2aX;uJIF{e2G7 NYPIVWxKUUN3MDC9JFAvODBzODFOwG0> MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZyMUezPUc,OTd4MEG3N|k9N2F-
adriamycin-resistant MCF7 NYTvSY9tTnWwY4Tpc44h[XO|YYm= NHHrfnlKSzVyIE2gPE4zKM7:TR?= MnTQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4MEG3N|koRjF5NkCxO|M6RC:jPh?=
RPMI8226 Ml3oR5l1d3SxeHnjbZR6KGG|c3H5 MUnHTVUxKD1iMD6wNFIh|ryP M17BWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
HT29 NX\BU2M3S3m2b4TvfIlkcXS7IHHzd4F6 MmHOS2k2OCB;IECuNFAzKM7:TR?= NV;CcVlwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
COLO205 NVjGNGJ3S3m2b4TvfIlkcXS7IHHzd4F6 MkHDS2k2OCB;IECuNFA{KM7:TR?= Mn\RQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
HCC2998 NVrpTXlyS3m2b4TvfIlkcXS7IHHzd4F6 NXyxdoJxT0l3MDC9JFAvODB|IN88US=> MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7NkOzNkc,OTd4OU[zN|I9N2F-
HS578T NULibXF1S3m2b4TvfIlkcXS7IHHzd4F6 NYPjeVJXT0l3MDC9JFAvODB|IN88US=> NGrBeoo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
PC3 NGOyXXhEgXSxdH;4bYNqfHliYYPzZZk> MnH2S2k2OCB;IECuNFA1KM7:TR?= M4ftWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
SNB75 MXjDfZRwfG:6aXPpeJkh[XO|YYm= NV3rcJJsT0l3MDC9JFAvODB2IN88US=> M{\WV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
A549 MmixR5l1d3SxeHnjbZR6KGG|c3H5 NEKxRoZIUTVyIE2gNE4xODRizszN M4jTOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
KM12 MmDYR5l1d3SxeHnjbZR6KGG|c3H5 NX\FWpV3T0l3MDC9JFAvODB2IN88US=> MkXlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
DU145 NEXmTndEgXSxdH;4bYNqfHliYYPzZZk> NIjCe|VIUTVyIE2gNE4xODVizszN M33XUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
SK-OV3 NFTEXG1EgXSxdH;4bYNqfHliYYPzZZk> MVHHTVUxKD1iMD6wNFgh|ryP MlrEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
NCI-H322M NGjOclJEgXSxdH;4bYNqfHliYYPzZZk> M1rqbmdKPTBiPTCwMlAyOyEQvF2= NV3USZc{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
UACC257 MkHBR5l1d3SxeHnjbZR6KGG|c3H5 NIDHZpFIUTVyIE2gNE4xPCEQvF2= M3r0TFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
HCT15 MUTDfZRwfG:6aXPpeJkh[XO|YYm= M3\yfWdKPTBiPTCwMlE2QCEQvF2= NHn1Ono9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
ACHN NF7mfIxEgXSxdH;4bYNqfHliYYPzZZk> NEXSV49IUTVyIE2gNE4{QThizszN MoHOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
HeLa MVHDfZRwfG:6aXPpeJkh[XO|YYm= MVXJR|UxKD1iMD6wNFU3KM7:TR?= NIn6U|A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{e2OFE1QCd-MUe3OlQyPDh:L3G+
MCF7 NHXwUHJEgXSxdH;4bYNqfHliYYPzZZk> MUDJR|UxKD1iMD6wNVI1KM7:TR?= M4rST|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5N{[0NVQ5Lz5zN{e2OFE1QDxxYU6=
A549 MVXDfZRwfG:6aXPpeJkh[XO|YYm= NFzKNJVKSzVyIE2gNE4xOTJ4IN88US=> M1K0[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5N{[0NVQ5Lz5zN{e2OFE1QDxxYU6=
HGC27 NFXUPFZEgXSxdH;4bYNqfHliYYPzZZk> NUTXN3pTUUN3MDC9JFAvPzd5ODFOwG0> MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzd4NEG0PEc,OTd5NkSxOFg9N2F-
HL60 M2DWZmN6fG:2b4jpZ4l1gSCjc4PhfS=> MUm3NkBp MlHUTWM2OCB;IECuPVMh|ryP M4rBU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OEm2PFE3Lz5zN{i5OlgyPjxxYU6=
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MESSA/DX5 NVzv[W46S3m2b4TvfIlkcXS7IHHzd4F6 M4jnUFczKGh? MUXJR|UxKD1iNTFOwG0> M{nrdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6M{C4OVY3Lz5zOEOwPFU3PjxxYU6=
K562 NUXqNIZMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4nnbVczKGh? M2\vS2lEPTBiPTCwMlAxODZizszN NGW5Sow9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOxN|MxPyd-MUizNVM{ODd:L3G+
KB3-1 NXHoUJpPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXvkdFhpPzJiaB?= MmHoTWM2OCB;IECuNFAzKM7:TR?= NInqfJQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOxN|MxPyd-MUizNVM{ODd:L3G+
HepG2 Mnf0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUO3NkBp NWjR[4E6UUN3MDC9JFAvODB5IN88US=> M4TMUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6M{GzN|A4Lz5zOEOxN|MxPzxxYU6=
KB V1 MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYS3NkBp MknpTWM2OCB;IEig{txO M1W5elxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6M{GzN|A4Lz5zOEOxN|MxPzxxYU6=
A549 NETnRnBEgXSxdH;4bYNqfHliYYPzZZk> MYizJIRigXN? NHrzOWhKSzVyIE2gNE4xODdizszN M17XS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEG5NVU1Lz5zOESxPVE2PDxxYU6=
MCF7 M1nPOmN6fG:2b4jpZ4l1gSCjc4PhfS=> MW[zJIRigXN? Mo\zTWM2OCB;IECuNFEyPyEQvF2= M3jFc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEG5NVU1Lz5zOESxPVE2PDxxYU6=
HepG2 NIT1W3pEgXSxdH;4bYNqfHliYYPzZZk> MkDFN{Bl[Xm| MXPJR|UxKD1iMD6wOFY5KM7:TR?= NFPkSmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOESxPVE2PCd-MUi0NVkyPTR:L3G+
MDA-MB-231 MYDDfZRwfG:6aXPpeJkh[XO|YYm= NYTNcJR2OyCmYYnz M17lS2lEPTBiPTCwMlA4ODNizszN NULhXGFDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0NVkyPTRpPkG4OFE6OTV2PD;hQi=>
Hep3B MUDDfZRwfG:6aXPpeJkh[XO|YYm= MXmzJIRigXN? NXrLNWtCUUN3MDC9JFAvOTNizszN MlrTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2MUmxOVQoRjF6NEG5NVU1RC:jPh?=
CCRF-CEM NUHxN2U6S3m2b4TvfIlkcXS7IHHzd4F6 MYq3NkBp MYDJR|UxKD1iMD6wNFEzPzRizszN M3vwRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEWwOFU3Lz5zOES1NFQ2PjxxYU6=
HCT116 MUTDfZRwfG:6aXPpeJkh[XO|YYm= M{jIVFczKGh? Mom3TWM2OCB;IECuNFAyOyEQvF2= NHezS3A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES1NFQ2Pid-MUi0OVA1PTZ:L3G+
MX1 NH;VZ41EgXSxdH;4bYNqfHliYYPzZZk> NGDy[lM4OiCq MYXJR|UxKD1iMD6wN|Uh|ryP MkPrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NUC0OVYoRjF6NEWwOFU3RC:jPh?=
HeLa NEPDR3NCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NY\OfW51PDhiaB?= MnHETWM2OCB;IECuNFAyPSEQvF2= NXHmdZV{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0OlE6QTdpPkG4OFYyQTl5PD;hQi=>
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U2OS M1n6cGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MXy0PEBp NIf6[pRKSzVyIE2gNE4xOjRizszN MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR4MUm5O{c,OTh2NkG5PVc9N2F-
A2780 MUHDfZRwfG:6aXPpeJkh[XO|YYm= MofXO|IhcA>? M2W5RmlEPTBiPTCwMlAxOTN6IN88US=> MmXOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NkW4OFYoRjF6NE[1PFQ3RC:jPh?=
MCF7 M2DOOWN6fG:2b4jpZ4l1gSCjc4PhfS=> NVPxZpVIPzJiaB?= M2jrWGlEPTBiPTCwMlAxOTdizszN M{DJNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NE[1PFQ3Lz5zOES2OVg1PjxxYU6=
LCC6 M{PjemN6fG:2b4jpZ4l1gSCjc4PhfS=> MUC3NkBp M4HyWmlEPTBiPTCwMlAxOzFizszN NFH0[pc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES2OVg1Pid-MUi0OlU5PDZ:L3G+
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NCI/ADR MojUR5l1d3SxeHnjbZR6KGG|c3H5 M2fkR|czKGh? NVf5VJpmUUN3MDC9JFAvOyEQvF2= NF;XWI49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES2OVg1Pid-MUi0OlU5PDZ:L3G+
1A9PTX10 MWfDfZRwfG:6aXPpeJkh[XO|YYm= MmiyO|IhcA>? NYPzSYpXUUN3MDC9JFAvPTN{OUWg{txO M{\CdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NE[1PFQ3Lz5zOES2OVg1PjxxYU6=
HT29 NYrFZop5SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MoTxS2k2OCB;IECuNFE2KM7:TR?= NUC3PYRtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1NFI3OzlpPkG4OVAzPjN7PD;hQi=>
M21 NGPFTmtCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NXW3TmFVT0l3MDC9JFAvODN5IN88US=> NFrxfI89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEWwNlY{QSd-MUi1NFI3Ozl:L3G+
MCF7 NVnKfpRqSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M13EbWdKPTBiPTCwMlA2PCEQvF2= MmTiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3MEK2N|koRjF6NUCyOlM6RC:jPh?=
HepG2 MkXWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4PyS|czKGh? MYjJR|UxKD1iMD6wNFU6KM7:TR?= MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDVzMkm4OEc,OTh3MUK5PFQ9N2F-
HepG2/Dox M2\lOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4f4UlczKGh? MkXjTWM2OCB;IEGuOEDPxE1? MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDVzMkm4OEc,OTh3MUK5PFQ9N2F-
HT29 NFjMPIdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYfjNYhHPDhiaB?= MUfHTVUxKD1iMD6wNVUh|ryP NH;SSlg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEW3PVM5Pyd-MUi1O|k{QDd:L3G+
M21 M3[1[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVe0PEBp NYPHeo5IT0l3MDC9JFAvODN5IN88US=> MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDV5OUO4O{c,OTh3N{mzPFc9N2F-
MCF7 MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXXWPYRmPDhiaB?= Mn\aS2k2OCB;IECuNFU1KM7:TR?= MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDV5OUO4O{c,OTh3N{mzPFc9N2F-
KB403 MWjDfZRwfG:6aXPpeJkh[XO|YYm= MX:yOEBp M1v6SWlEPTBiPTCwMlAxOSEQvF2= MlmxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3OE[0PVEoRjF6NUi2OFkyRC:jPh?=
WRL68 MnvER5l1d3SxeHnjbZR6KGG|c3H5 NVXRVpd{OjRiaB?= NHrNO|RKSzVyIE2gNE4xODRizszN NVzNbFVuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1PFY1QTFpPkG4OVg3PDlzPD;hQi=>
MCF7 M4TJOmN6fG:2b4jpZ4l1gSCjc4PhfS=> NFXrT2EzPCCq NUmzfosyUUN3MDC9JFAvODB4IN88US=> M4r0fFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NUi2OFkyLz5zOEW4OlQ6OTxxYU6=
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HEPG2 MXjDfZRwfG:6aXPpeJkh[XO|YYm= MW[yOEBp MnPwTWM2OCB;IECuNFA6KM7:TR?= MnnxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3OE[0PVEoRjF6NUi2OFkyRC:jPh?=
HCT116 MkixR5l1d3SxeHnjbZR6KGG|c3H5 NVy0[mZYUUN3MDC9JFAvODF|NjFOwG0> NWHT[Y9WRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi2NFY2PDBpPkG4OlA3PTRyPD;hQi=>
SF268 NHjWS3ZEgXSxdH;4bYNqfHliYYPzZZk> NHLxVlBKSzVyIE2gNE4xOTV|IN88US=> MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZyNkW0NEc,OTh4ME[1OFA9N2F-
A549 MUjDfZRwfG:6aXPpeJkh[XO|YYm= MX;JR|UxKD1iMD6wNlMyKM7:TR?= M1jzdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NkC2OVQxLz5zOE[wOlU1ODxxYU6=
MDA-MB-231 NEHBcJdEgXSxdH;4bYNqfHliYYPzZZk> NX;CeWJJUUN3MDC9JFAvODRyNTFOwG0> MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZyNkW0NEc,OTh4ME[1OFA9N2F-
SF295 M3jQUmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVTGfpJ[UUN3MDC9JFAvOjlizszN MlvEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4ME[1OFAoRjF6NkC2OVQxRC:jPh?=
MDA-MB-435 M4jhV2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NWnUTnR[PzJiaB?= NUPtR|hET0l3MDC9JFAvODB2IN88US=> MnLZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4MUC5PVUoRjF6NkGwPVk2RC:jPh?=
HT29 M{ezTmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M4rPVVQ5KGh? NEfzXJNIUTVyIE2gNE4xOTVizszN NF;xVXc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOE[xO|QyPCd-MUi2NVc1OTR:L3G+
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Eca109 NHOyO5NEgXSxdH;4bYNqfHliYYPzZZk> MmSxTWM2OCB;IEKuO|Mh|ryP NEizVGU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEewNVI5OSd-MUi3NFEzQDF:L3G+
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MCF7 NGjMTmREgXSxdH;4bYNqfHliYYPzZZk> NIfCN2NKSzVyIE2gNk46QCEQvF2= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDdyMUK4NUc,OTh5MEGyPFE9N2F-
HeLa MkDmR5l1d3SxeHnjbZR6KGG|c3H5 NHnIPVlKSzVyIE2gN{4yOSEQvF2= MlzGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5MEGyPFEoRjF6N{CxNlgyRC:jPh?=
HCT8 MXPDfZRwfG:6aXPpeJkh[XO|YYm= NF\tWW5KSzVyIE2gN{4zQSEQvF2= NUXGZVN[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3NFEzQDFpPkG4O|AyOjhzPD;hQi=>
K562 NXK3bXl3S3m2b4TvfIlkcXS7IHHzd4F6 MWHJR|UxKD1iMz62OUDPxE1? MlzTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5MEGyPFEoRjF6N{CxNlgyRC:jPh?=
HepG2 M1LWcGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M3LYZlQ5KGh? NXTmVJo4UUN3MDC9JFAvPjJizszN NV64TIs1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3NFE{ODFpPkG4O|AyOzBzPD;hQi=>
PC3 MoD5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NWPyVllyPDhiaB?= NEjBS3FKSzVyIE2gNk44OyEQvF2= MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDdyMUOwNUc,OTh5MEGzNFE9N2F-
HCT116 NGjQNY9CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MWC0PEBp MoHaTWM2OCB;IE[uNVgh|ryP NWW4S5F3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3NFE{ODFpPkG4O|AyOzBzPD;hQi=>
A549 MX;DfZRwfG:6aXPpeJkh[XO|YYm= NUntWHdpUUN3MDC9JFAvODB{IN88US=> NYXZdldkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3NVU4QDJpPkG4O|E2Pzh{PD;hQi=>
CCRF-CEM M4[3cGN6fG:2b4jpZ4l1gSCjc4PhfS=> MW[3NkBp NXLJOY5HUUN3MDC9JFAvODBzMTFOwG0> M{fMdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{WyPFY6Lz5zOEe1Nlg3QTxxYU6=
SKOV3 Mm\TRY51cWOjbnPldkBie3OjeR?= MVO3NkBp NV;VfXZTUUN3MDC9JFAvODBzM{Sg{txO NYTvTJZrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3OlI{PThpPkG4O|YzOzV6PD;hQi=>
MCF7 M3;OUmN6fG:2b4jpZ4l1gSCjc4PhfS=> NEHhVVVGTDVyIE2gNE4xODN{IN88US=> MlKyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7Mk[3NFEoRjF6OUK2O|AyRC:jPh?=
NCI/ADR-RES MXLDfZRwfG:6aXPpeJkh[XO|YYm= M3X0dGVFPTBiPTCxMlUh|ryP NF\LWm09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEmyOlcxOSd-MUi5NlY4ODF:L3G+
PANC1 NXrCU5BMS3m2b4TvfIlkcXS7IHHzd4F6 NUP5WlI5PzJiaB?= M4DleWlEPTBiPTCwMlAxQTlizszN MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDl3MUe4O{c,OTh7NUG3PFc9N2F-
DLD1 M4XqWGN6fG:2b4jpZ4l1gSCjc4PhfS=> MlrCO|IhcA>? NV\5XoJWUUN3MDC9JFAvODJ{IN88US=> NInZ[IY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEm1NVc5Pyd-MUi5OVE4QDd:L3G+
AsPC1 MkDsR5l1d3SxeHnjbZR6KGG|c3H5 NFjZRXE4OiCq MWfJR|UxKD1iMD6wPFkh|ryP NVfncoZCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5OVE4QDdpPkG4PVUyPzh5PD;hQi=>
NCI/ADR-RES NUP2SndoS3m2b4TvfIlkcXS7IHHzd4F6 MYq3NkBp NGDDWlNKSzVyIE2gNU4{KM7:TR?= NHjDW5A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEm1NVc5Pyd-MUi5OVE4QDd:L3G+
MCF7 MofYR5l1d3SxeHnjbZR6KGG|c3H5 MmfWSWQ2OCB;IECuNFAzOSEQvF2= MmTNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7N{e2OVkoRjF6OUe3OlU6RC:jPh?=
NCI/ADR-RES MYnDfZRwfG:6aXPpeJkh[XO|YYm= MoHxSWQ2OCB;IEKg{txO NHmxUGY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEm3O|Y2QSd-MUi5O|c3PTl:L3G+
A431 MWDDfZRwfG:6aXPpeJkh[XO|YYm= MkXHO|IhcA>? MV3JR|UxKD1iMD6wNlUyKM7:TR?= NUXKW2hvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5PVA2PzRpPkG4PVkxPTd2PD;hQi=>
MCF7 NVzwN5F7S3m2b4TvfIlkcXS7IHHzd4F6 NV7jdYg2PzJiaB?= Mn7vTWM2OCB;IECuNFM6KM7:TR?= M4ryc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUmwOVc1Lz5zOEm5NFU4PDxxYU6=
MDA-MB-231 M2nIXGN6fG:2b4jpZ4l1gSCjc4PhfS=> NVvkNVdVPzJiaB?= Mn;FTWM2OCB;IECuNFQ4OSEQvF2= MmXLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7OUC1O|QoRjF6OUmwOVc1RC:jPh?=
SKOV3 MlTqR5l1d3SxeHnjbZR6KGG|c3H5 NXqydZcxPzJiaB?= NYDYPZZvUUN3MDC9JFAvODZ3ODFOwG0> M1L5UlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUmwOVc1Lz5zOEm5NFU4PDxxYU6=
PANC1 M{W1fWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFzI[2Q4OiCq MYXJR|UxKD1iMD6wNFk6KM7:TR?= M{TCbVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEKyOlc6Lz5zOUCyNlY4QTxxYU6=
DLD1 NV:0XIhRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUe3NkBp NF\DR|ZKSzVyIE2gNE4xOjJizszN M3nQVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEKyOlc6Lz5zOUCyNlY4QTxxYU6=
AsPC1 MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXTUWWJGPzJiaB?= M1\jWGlEPTBiPTCwMlA5QSEQvF2= NIjXeG49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUCyNlY4QSd-MUmwNlI3Pzl:L3G+
NCI/ADR NUjh[YxWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlvCO|IhcA>? NVzGemNTUUN3MDC9JFEvOyEQvF2= NX3CXlNDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNlI3PzlpPkG5NFIzPjd7PD;hQi=>
A2780 M4PuWmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MnfXNkBl[Xm| NWPJWmZTUUN3MDC9JFAvODJ|NDFOwG0> MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB{OEGwNkc,OTlyMkixNFI9N2F-
KB MVfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MkjvN{Bl[Xm| MlfMTWM2OCB;IECuNFAzPSEQvF2= MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB2MUK0O{c,OTlyNEGyOFc9N2F-
COLO205 NWLZN2dYSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MXeyOEBp M4H3SmlEPTBiPTCwMlAxOzNizszN MoDGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNEGyOFcoRjF7MESxNlQ4RC:jPh?=
KB 8.5 MoXRRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NEHOXo8{KGSjeYO= MlLiTWM2OCB;IECuNFI3KM7:TR?= MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB2MUK0O{c,OTlyNEGyOFc9N2F-
KBV1 M1LweGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MlrRN{Bl[Xm| NV;QdI5oUUN3MDC9JFIvODF|IN88US=> NWnaPGdqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOFEzPDdpPkG5NFQyOjR5PD;hQi=>
KB NH3tW5lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlnRO|IhcA>? NXe5UoFvUUN3MDC9JFAvODB|MzFOwG0> MmfmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3O|MoRjF7MEWzO|c{RC:jPh?=
KB-7D NVjOOnllT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml;yO|IhcA>? MlfXTWM2OCB;IECuNFA4QSEQvF2= M1W5T|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|c{Lz5zOUC1N|c4OzxxYU6=
Pgp170 overexpressing multidrug resistant-KB-TAX50 MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4Gx[VczKGh? NGD0UplKSzVyIE2gNE4zPzNizszN NYLGd2RkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4PzNpPkG5NFU{Pzd|PD;hQi=>
NPC-TW01 MWTDfZRwfG:6aXPpeJkh[XO|YYm= M4DJSFczKGh? NVH5eYhXUUN3MDC9JFAvODB4IN88US=> MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3M{e4NUc,OTlyNUO3PFE9N2F-
MES-SA NX7GUmJ2S3m2b4TvfIlkcXS7IHHzd4F6 NWLPbpB4PzJiaB?= NFSzeZlKSzVyIE2gNE4xODhizszN M2XDXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|gyLz5zOUC1N|c5OTxxYU6=
NCI-H838 MUHDfZRwfG:6aXPpeJkh[XO|YYm= Mlq3O|IhcA>? MXfJR|UxKD1iMD6wNlYh|ryP MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3M{e4NUc,OTlyNUO3PFE9N2F-
HCT116 MmO2R5l1d3SxeHnjbZR6KGG|c3H5 NYXW[IM5PzJiaB?= NXvkZoxzUUN3MDC9JFAvODZzIN88US=> MmnuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3PFEoRjF7MEWzO|gyRC:jPh?=
cells after 72 hrs by MTT assay MUjDfZRwfG:6aXPpeJkh[XO|YYm= M{DBRmlEPTBiPTC1MlE1KM7:TR?= NFTYUJI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC1N|c5OSd-MUmwOVM4QDF:L3G+
Hep3B NID2OohEgXSxdH;4bYNqfHliYYPzZZk> NGTqUFk4OiCq MWLJR|UxKD1iNz6yOkDPxE1? MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3M{e4NUc,OTlyNUO3PFE9N2F-
A498 M1PMNGN6fG:2b4jpZ4l1gSCjc4PhfS=> Mnv3O|IhcA>? MWHJR|UxKD1iOD64NUDPxE1? MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3M{e4NUc,OTlyNUO3PFE9N2F-
NB4 MVjDfZRwfG:6aXPpeJkh[XO|YYm= MnPiOFghcA>? NV\FW5N6UUN3MDC9JFAvOSEQvF2= NIHudGQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC3NlIxQSd-MUmwO|IzODl:L3G+
A549 NV3jeoZ[S3m2b4TvfIlkcXS7IHHzd4F6 NInySWg1QCCq NIPkT2JKSzVyIE2gNE4yKM7:TR?= M4DoV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEeyNlA6Lz5zOUC3NlIxQTxxYU6=
MCF7 MnLvR5l1d3SxeHnjbZR6KGG|c3H5 MmeyOFghcA>? MmfkTWM2OCB;IECuNUDPxE1? NFLoV5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC3NlIxQSd-MUmwO|IzODl:L3G+
SH-SY5Y NH:x[nFEgXSxdH;4bYNqfHliYYPzZZk> NW\TSmdsPDhiaB?= NFXyRphKSzVyIE2gNE4zKM7:TR?= MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB5MkKwPUc,OTlyN{KyNFk9N2F-
PC3 M2n4XGN6fG:2b4jpZ4l1gSCjc4PhfS=> NHfob4I1QCCq MorITWM2OCB;IECuNkDPxE1? MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB5MkKwPUc,OTlyN{KyNFk9N2F-
DLD1 MnTzR5l1d3SxeHnjbZR6KGG|c3H5 NELrd4w4OiCq NIe3OYRIUTVyIE2gNE4xOSEQvF2= MnTSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyOEGyOFkoRjF7MEixNlQ6RC:jPh?=
B16 MkfhR5l1d3SxeHnjbZR6KGG|c3H5 NWLOSmhmPzJiaB?= NVHIT5pXT0l3MDC9JFAvODFizszN MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB6MUK0PUc,OTlyOEGyOFk9N2F-
A172 NG\VXZpEgXSxdH;4bYNqfHliYYPzZZk> MUW3NkBp M2nHZmdKPTBiPTCwMlAyKM7:TR?= M3y3RlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEixNlQ6Lz5zOUC4NVI1QTxxYU6=
HeLa NYH2S2RiS3m2b4TvfIlkcXS7IHHzd4F6 MnHoO|IhcA>? NUn5dVZYT0l3MDC9JFAvODJizszN MkjzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyOEGyOFkoRjF7MEixNlQ6RC:jPh?=
U87 M3HFWWN6fG:2b4jpZ4l1gSCjc4PhfS=> M{TjdlczKGh? NFfoTWVIUTVyIE2gNE4xOiEQvF2= M2PndlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEixNlQ6Lz5zOUC4NVI1QTxxYU6=
SiHa MVXDfZRwfG:6aXPpeJkh[XO|YYm= M{mzUVczKGh? M2X4dmdKPTBiPTCwMlA{KM7:TR?= NEXqNpk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC4NVI1QSd-MUmwPFEzPDl:L3G+
HeLa MnTkRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MVK5OkBp NHSx[nNKSzVyIE2gNE4xODFizszN NV;Feod6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwPVE2PzlpPkG5NFkyPTd7PD;hQi=>
SKOV3 M2HkeGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NYHybG0xQTZiaB?= NGqybpNKSzVyIE2gNE4xOTZizszN NHLhepY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC5NVU4QSd-MUmwPVE2Pzl:L3G+
BGC823 NHntdlFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= Mo\mPVYhcA>? MUfJR|UxKD1iMD6wNVg6KM7:TR?= Mn3oQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyOUG1O|koRjF7MEmxOVc6RC:jPh?=
HCT116 M3W5OWN6fG:2b4jpZ4l1gSCjc4PhfS=> NFTHeYc4OiCq MnL6TWM2OCB;IECuNFAyOSEQvF2= MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF{NEK1NEc,OTlzMkSyOVA9N2F-
CCRF-CEM MnrKR5l1d3SxeHnjbZR6KGG|c3H5 NV\UUnR{PzJiaB?= Ml;oTWM2OCB;IECuNFA{OSEQvF2= NFe0fZo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUGyOFI2OCd-MUmxNlQzPTB:L3G+
MX1 NVvoT4tuS3m2b4TvfIlkcXS7IHHzd4F6 NVzFSWZGPzJiaB?= MVvJR|UxKD1iMD6wOFYh|ryP NFHTV2Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUGyOFI2OCd-MUmxNlQzPTB:L3G+
HCT116 NUHiTZZWS3m2b4TvfIlkcXS7IHHzd4F6 M{XC[VQh\GG7cx?= M2e5XGlEPTBiPTCwMlAxOTFizszN NWjPbWZvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmxNlgyPTZpPkG5NVI5OTV4PD;hQi=>
HT-29 MmP1R5l1d3SxeHnjbZR6KGG|c3H5 MnPxOEBl[Xm| MkS5TWM2OCB;IECuNFA{PiEQvF2= NHjp[os9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUGyPFE2Pid-MUmxNlgyPTZ:L3G+
A2780 MW\DfZRwfG:6aXPpeJkh[XO|YYm= NH;JWVY1QCCq NWi4cYZIUUN3MDC9JFAvODBzMzFOwG0> MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF{OEm3Nkc,OTlzMki5O|I9N2F-
KB M{n6Xmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MV7FSFUxKD1iMD6wNlMh|ryP MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF4MUOxOkc,OTlzNkGzNVY9N2F-
HepG2 MWfDfZRwfG:6aXPpeJkh[XO|YYm= MkPYS2k2OCB;IECuNFAyKM7:TR?= NFKxfoc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUG5OVkxOSd-MUmxPVU6ODF:L3G+
WI38 MoHWR5l1d3SxeHnjbZR6KGG|c3H5 NHXrRY5IUTVyIE2gNE4xOTN5IN88US=> NEXIW409[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUG5OVkxOSd-MUmxPVU6ODF:L3G+
RKO NFP4bmpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MmW4TWM2OCB;IECuNFIh|ryP NV\oSWdkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyNlAxOThpPkG5NlIxODF6PD;hQi=>
KB/HeLa M{D3XGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M{T2ZmlEPTBiPTCwMlA{KM7:TR?= NWnNPG9kRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyNlAxOThpPkG5NlIxODF6PD;hQi=>
SKOV3 MmLTRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NHKzenBKSzVyIE2gNE4xPSEQvF2= NF3JNI49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKyNFAyQCd-MUmyNlAxOTh:L3G+
SF268 NUjWeHpiSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MlvITWM2OCB;IECuNFUh|ryP M{HZVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkKwNFE5Lz5zOUKyNFAyQDxxYU6=
P388 M4HYc2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NGD1UoQ1QCCq NIOzVopKSzVyIE2gNE4xPSEQvF2= M{\uNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkKwNFE5Lz5zOUKyNFAyQDxxYU6=
cells ectopic expression of human NH7XemNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NYTv[I5oPDhiaB?= MmLjTWM2OCB;IECuNFUh|ryP MoDQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{MkCwNVgoRjF7MkKwNFE5RC:jPh?=
L1210 NYTJOoJvSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NWj3eohyPDhiaB?= MlP0TWM2OCB;IECuNFYh|ryP MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ{MECxPEc,OTl{MkCwNVg9N2F-
NCI-H460 NFXaSGJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M1XqS2lEPTBiPTCwMlA4KM7:TR?= MlnNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{MkCwNVgoRjF7MkKwNFE5RC:jPh?=
Mny2RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NEe4VZU1QCCq NXT6RnhVUUN3MDC9JFAvOyEQvF2= NV;KSGNzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyNlAxOThpPkG5NlIxODF6PD;hQi=>
MCF7 M4PwTmN6fG:2b4jpZ4l1gSCjc4PhfS=> MXy3NkBp NEnvR2NKSzVyIE2gNE4xODF{IN88US=> MoS3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
A2780 M3:xeWN6fG:2b4jpZ4l1gSCjc4PhfS=> NInzOlY4OiCq MVvJR|UxKD1iMD6wNFE{QCEQvF2= NELKeVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKzPVI1OCd-MUmyN|kzPDB:L3G+
wild type A2780 NWTDZ2FES3m2b4TvfIlkcXS7IHHzd4F6 NU\MfXdwPzJiaB?= MVXJR|UxKD1iMD6wNFE4KM7:TR?= NYTHVmx2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyN|kzPDBpPkG5NlM6OjRyPD;hQi=>
cisplatin-resistant A2780 M33nfmN6fG:2b4jpZ4l1gSCjc4PhfS=> NInJW3k4OiCq MmS5TWM2OCB;IECuNFAzOiEQvF2= MnuwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
LCC-6 M{jS[2N6fG:2b4jpZ4l1gSCjc4PhfS=> MUK3NkBp MVTJR|UxKD1iMD6wNFI1PSEQvF2= M4HsWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkO5NlQxLz5zOUKzPVI1ODxxYU6=
HT-29 MnT1R5l1d3SxeHnjbZR6KGG|c3H5 NX7abIU2PzJiaB?= NV;hRpA2UUN3MDC9JFAvODB|NjFOwG0> MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ|OUK0NEc,OTl{M{myOFA9N2F-
H460 NH\GXGVEgXSxdH;4bYNqfHliYYPzZZk> NWrDOlBTPzJiaB?= M{\QVWlEPTBiPTCwMlAxPDlizszN MoTtQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
topotecan-resistant A2780 MXLDfZRwfG:6aXPpeJkh[XO|YYm= NFPu[W44OiCq Mmn3TWM2OCB;IECuNFA4OiEQvF2= NXGzenpmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyN|kzPDBpPkG5NlM6OjRyPD;hQi=>
PANC1 NVLqWJVlS3m2b4TvfIlkcXS7IHHzd4F6 MnvKO|IhcA>? NVm0UVZ1UUN3MDC9JFAvODJ3NzFOwG0> NELFZ2M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKzPVI1OCd-MUmyN|kzPDB:L3G+
1A9PTX22 NXzoOGo2S3m2b4TvfIlkcXS7IHHzd4F6 MoDxO|IhcA>? M3fMc2lEPTBiPTCwMlE3ODdizszN MlvSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
NCI/ADR M170OGN6fG:2b4jpZ4l1gSCjc4PhfS=> NEj1eWM4OiCq MUDJR|UxKD1iMD6zJO69VQ>? MmPUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
A2780 NHmzbmZHfW6ldHnvckBie3OjeR?= NFfue2hKSzVyIE2gNE4{QDZizszN NFnnTlM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKzPVI1OCd-MUmyN|kzPDB:L3G+
1A9PTX10 MV\DfZRwfG:6aXPpeJkh[XO|YYm= MVq3NkBp NVHRXmRYUUN3MDC9JFAvPTN{OUWg{txO MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ|OUK0NEc,OTl{M{myOFA9N2F-
A2780/ADR NHuxUopEgXSxdH;4bYNqfHliYYPzZZk> MkX6O|IhcA>? MlXYTWM2OCB;IEGuNlM6KM7:TR?= NYL0W4dPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyN|kzPDBpPkG5NlM6OjRyPD;hQi=>
A549 NUnHcVZoS3m2b4TvfIlkcXS7IHHzd4F6 MXiyOEBp MWHJR|UxKD1iMD6wNFUzKM7:TR?= NXTRNmRrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyOFUzPjFpPkG5NlQ2OjZzPD;hQi=>
PC3M M{DQWGN6fG:2b4jpZ4l1gSCjc4PhfS=> MlPNNlQhcA>? M2LzU2lEPTBiPTCwMlAzPyEQvF2= Moj4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{NEWyOlEoRjF7MkS1NlYyRC:jPh?=
HCT8 NXzrdZE2S3m2b4TvfIlkcXS7IHHzd4F6 MkfLNlQhcA>? NIXBdJNKSzVyIE2gNE4xOzdizszN NXvUZ|dERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyOFUzPjFpPkG5NlQ2OjZzPD;hQi=>
Bel7402 MYfDfZRwfG:6aXPpeJkh[XO|YYm= MofNNlQhcA>? MkG1TWM2OCB;IECuNFk2KM7:TR?= MlO3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{NEWyOlEoRjF7MkS1NlYyRC:jPh?=
A2780 NIfwXHREgXSxdH;4bYNqfHliYYPzZZk> NUH1UXBlUUN3MDC9JFAvODF2IN88US=> M2rpe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkiyNVg3Lz5zOUK4NlE5PjxxYU6=
SNU398 M{fHcWFxd3C2b4Ppd{Bie3OjeR?= Ml;JOFghcA>? MoXOS2k2OCB;IECuNFEh|ryP MlW3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{OEKxPFgoRjF7MkiyNVg5RC:jPh?=
HCT116 NI\yT3dCeG:ydH;zbZMh[XO|YYm= NWfPe5F4PDhiaB?= Mmf4SWM2OCB;IECuNFI{KM7:TR?= NV30VIRqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyPFIyQDhpPkG5NlgzOTh6PD;hQi=>
T47D MnPzRZBweHSxc3nzJIF{e2G7 NG[2SZc1QCCq NET0c|FGSzVyIE2gNE4xOzVizszN MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ6MkG4PEc,OTl{OEKxPFg9N2F-
PC3 NELufnlEgXSxdH;4bYNqfHliYYPzZZk> NHrFWVc1KGSjeYO= NXfqOYlTUUN3MDC9JFAvODBzNDFOwG0> MmDHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl|NUmxOlkoRjF7M{W5NVY6RC:jPh?=
A2780 M{XLTGN6fG:2b4jpZ4l1gSCjc4PhfS=> M17sUFQh\GG7cx?= NXTkO5BZUUN3MDC9JFAvODF2OTFOwG0> MkfkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl|NUmxOlkoRjF7M{W5NVY6RC:jPh?=
K562 MoLYR5l1d3SxeHnjbZR6KGG|c3H5 MYe0PEBp NXPaXIN2UUN3MDC9JFEvOTZizszN MmHsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl|NUmxPFUoRjF7M{W5NVg2RC:jPh?=
MCF7 M{HCc2N6fG:2b4jpZ4l1gSCjc4PhfS=> MUS0PEBp NIW1V2lKSzVyIE2gNk4yOSEQvF2= NV2zSGdERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmzOVkyQDVpPkG5N|U6OTh3PD;hQi=>
A549 NH20VYpEgXSxdH;4bYNqfHliYYPzZZk> M{S4