Paclitaxel

For research use only. Not for use in humans.

製品コードS1150 別名:NSC 125973, PTX, Taxol, Onxal, Abraxane

Paclitaxel化学構造

CAS No. 33069-62-4

Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.

サイズ 価格(税別)  
10mM (1mL in DMSO) JPY 17100
JPY 13600
JPY 46800
JPY 69700
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バルク問合せ

文献中Selleckの製品使用例(236)

製品安全説明書

Antineoplastic and Immunosuppressive Antibiotics阻害剤の選択性比較

生物活性

製品説明 Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
ターゲット
Microtubule (human endothelial cells) [1]
0.1 pM
体外試験

Paclitaxel inhibits non-endothelial type human cells at 104 - to 105 -fold higher concentrations, with IC50 of 1 nM-10 nM. The selectivity of Paclitaxel inhibition of cell proliferation is also species specific, as mouse ECs are not sensitive to Paclitaxel at ultra low concentrations. Inhibition of human ECs by Paclitaxel at ultra low concentrations does not affect the cellular microtubule structure, and the treated cells do not show G2/M cell cycle arrest and apoptosis, suggesting a novel but as yet unidentified mechanism of action. In an in vitro angiogenesis assay, Paclitaxel at ultra low concentrations blocks human ECs from forming sprouts and tubes in the three-dimensional fibrin matrix. [1] In the presence of SMF, the efficient concentration of Paclitaxel on K562 cells is decreased from 50 to 10 ng/mL. The cell cycle arrest effect of Paclitaxel with or without SMF on K562 cells is correlated with DNA damage. [2] Paclitaxel alone causes a time-dependent inhibition of CDK1 in four cell lines including A549 cells, H358, H1395 cells and H1666 cells. [3]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
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EKVX NWfl[lMzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NGq4NGhKSzVyIE2gO{4yPjh4NTFOwG0> MlzRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
NB14 M4HjNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHPye25KSzVyIE2gO{45OTN7IN88US=> NFLFRZk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
ES5 NXizSGlCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXjJR|UxKD1iNz64OlY3OiEQvF2= NF;CSFI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
SK-MEL-2 MmW2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGj3VIdKSzVyIE2gPE41PTl5NjFOwG0> NIq0O2g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
COLO-800 NGDyfGlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mlf5TWM2OCB;IEiuOFc5PyEQvF2= NFH6Tm49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
EB2 NWSyR4JGT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4nhVWlEPTBiPTC5MlE6QDN3IN88US=> MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
ES3 M2XqSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFfjRldKSzVyIE2gPU4{ODZ4NTFOwG0> M3;QRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
SKM-1 NXnjSVI6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1zEfGlEPTBiPTC5MlM6PDV7IN88US=> Mo\lQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
MFM-223 M{TXW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIHBTYVKSzVyIE2gPU42ODF{NzFOwG0> MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
LB2241-RCC M4\mO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NFTwSYdKSzVyIE2gNVAvODN6NjFOwG0> NGmwTXU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
EW-13 NYjkPIR3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYTJR|UxKD1iMUCuN|M{OyEQvF2= MnjTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
D-283MED NH7iV2tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnTHTWM2OCB;IEGwMlQ6PTlizszN MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
EW-11 NILzOWdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX3WPGNFUUN3MDC9JFEyNjZ4OUSg{txO M3TIPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
NCI-H128 MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYPvO|g{UUN3MDC9JFEzNjF|M{Sg{txO M1LvS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
ES7 M1vKVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1zuW2lEPTBiPTCxOU4zPDl2IN88US=> NFr6SYQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
AM-38 NELtZnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4XvPGlEPTBiPTCxOU41OTZ4IN88US=> MoTVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
NCI-H716 M2\1UWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnPzTWM2OCB;IEG3MlkzQTlizszN Mlf6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
NCI-H1770 NFzLNnpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Ml[1TWM2OCB;IEG4MlM5PTFizszN NFrKd4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
JVM-3 NHK4bJJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MULJR|UxKD1iMkCuPFk5PSEQvF2= Mo\QQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
CW-2 NGjldW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWTadI1uUUN3MDC9JFIyNjF|NEmg{txO NV:y[XpMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
YT MVHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1PLZWlEPTBiPTCyNU41PjlzIN88US=> NGnx[Vc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
C8166 MkW0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVjJR|UxKD1iMkKuNlc1PiEQvF2= MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
SUP-T1 NHTFWpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUXIR5dOUUN3MDC9JFI{NjJ3MUKg{txO NHPZWIs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
KASUMI-1 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1fMRmlEPTBiPTCyN{42OTF7IN88US=> NH3jSpY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
IM-9 MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4HWPGlEPTBiPTCyN{43QTd7IN88US=> NILPOHg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
NH-12 MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlz6TWM2OCB;IEK0MlE3PTRizszN NWjCZos6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
WSU-NHL NEW0bnNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH71bVVKSzVyIE2gNlUvPzJ4MTFOwG0> MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
TUR NEmwUIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NHPRZmNKSzVyIE2gNlYvPjV|MzFOwG0> MlPMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
RL MnO1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{XpTWlEPTBiPTCyO{4zOjR{IN88US=> MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
EW-12 NIHtPWNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnzlTWM2OCB;IEK4MlA4ODJizszN Mn24QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
KG-1 NFOybVBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MofzTWM2OCB;IEK4MlI5PjVizszN M3;Fd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
P31-FUJ MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWn6W5VLUUN3MDC9JFI6NjB2OEmg{txO MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
NB10 MYTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn[yTWM2OCB;IEOxMlUxQSEQvF2= MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
COLO205 MXTDfZRwfG:6aXPpeJkh[XO|YYm= M2\iZ2dKPTBiPTCwMlAxOTd4IN88US=> MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek84QTB6OUWwK|44QTB6OUWwQE9iRg>?
SF539 MofXR5l1d3SxeHnjbZR6KGG|c3H5 NV2zWVhET0l3MDC9JFAvODB|Nk[g{txO M3PwelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzd7MEi5OVAoRjd7MEi5OVA9N2F-
SNB75 M{PXWmN6fG:2b4jpZ4l1gSCjc4PhfS=> M3LFRWdKPTBiPTCwMlAxQDB6IN88US=> NIf0OI49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95OUC4PVUxLz55OUC4PVUxRC:jPh?=
DMS114 M2X6PWN6fG:2b4jpZ4l1gSCjc4PhfS=> MmDQS2k2OCB;IECuNFEzOyEQvF2= NWS0bok{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{mwPFk2OCd-N{mwPFk2ODxxYU6=
OVCAR-3 MXHDfZRwfG:6aXPpeJkh[XO|YYm= NULHUZp5T0l3MDC9JFAvODF7NzFOwG0> MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek84QTB6OUWwK|44QTB6OUWwQE9iRg>?
NCI-H460 MkDmR5l1d3SxeHnjbZR6KGG|c3H5 MnGyS2k2OCB;IECuNFIyQSEQvF2= NUDwO2dqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{mwPFk2OCd-N{mwPFk2ODxxYU6=
HOP62 M3K0ZmN6fG:2b4jpZ4l1gSCjc4PhfS=> MmTDS2k2OCB;IECuNFY4OSEQvF2= Mn:wQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzlyOEm1NEc,PzlyOEm1NFww[T5?
mammary carcinoma M33pRmN6fG:2b4jpZ4l1gSCjc4PhfS=> M4\SWGlEPTBiPTCwMlI6QSEQvF2= Ml7rQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQDF6Mk[5PEc,QDF6Mk[5PFww[T5?
NCI60 Mke0R5l1d3SxeHnjbZR6KGG|c3H5 NVXyc5R7T0l3MDC9JFAvODByNkWg{txO NWPUS4lxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOUS2NVY2Oyd-OUS2NVY2OzxxYU6=
MCF-7 NFu2PXJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV3lSFduT0l3MDC9JFAvODBzMTFOwG0> NFTTVFc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi97OEezOVk4Lz57OEezOVk4RC:jPh?=
murine leukemic P388 NVzIZpJLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoWyS2k2OCB;IECuNFE3KM7:TR?= MkTtQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwQTh5M{W5O{c,QTh5M{W5O|ww[T5?
KB NHfBPJZEgXSxdH;4bYNqfHliYYPzZZk> MmXuTWM2OCB;IECuNFA3KM7:TR?= M3jFdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFyOUe4NlAxLz5zMEm3PFIxODxxYU6=
MCF7 NULYW5J4SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MYS3NkBp M3fHWmlEPTBiPTCwMlAxOiEQvF2= MoPWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF|MkWyNlYoRjFzM{K1NlI3RC:jPh?=
MCF-7 M{PX[GN6fG:2b4jpZ4l1gSCjc4PhfS=> M1\4N2VFPTBiPTCwMlAxPCEQvF2= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTN|NEW2O{c,OTF|M{S1Olc9N2F-
uterine sarcoma (MES-SA) MXzDfZRwfG:6aXPpeJkh[XO|YYm= MnHDTWM2OCB;IECuNFAxODRizszN M37kSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzN{K4NVkyLz5zMUeyPFE6OTxxYU6=
nonsmall cell lung carcinoma (NCI-H460) NGfrPGFEgXSxdH;4bYNqfHliYYPzZZk> MoDNTWM2OCB;IECuNFAxOTRizszN NHTqTlA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUeyPFE6OSd-MUG3NlgyQTF:L3G+
colon adenocarcinoma (HT-29) MYjDfZRwfG:6aXPpeJkh[XO|YYm= NHnh[2JKSzVyIE2gNE4xODBzNjFOwG0> NWfteWNQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUG3NlgyQTFpPkGxO|I5OTlzPD;hQi=>
prostate carcinoma (DU-145) MWnDfZRwfG:6aXPpeJkh[XO|YYm= Ml;4TWM2OCB;IECuNFA1QDlizszN Mm\YQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF5MkixPVEoRjFzN{K4NVkyRC:jPh?=
SW626 MkLDR5l1d3SxeHnjbZR6KGG|c3H5 MlfCO|IhcA>? MoTjTWM2OCB;IECuNFAxODFizszN MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjB6OESyOUc,OTJyOEi0NlU9N2F-
Lu1 MWTDfZRwfG:6aXPpeJkh[XO|YYm= M{\UPVczKGh? M1fEUGlEPTBiPTCwMlAyKM7:TR?= MlPaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJyOEi0NlUoRjF{MEi4OFI2RC:jPh?=
MCF7 MXjDfZRwfG:6aXPpeJkh[XO|YYm= NEPOe5E4OiCq NY\1NYgxUUN3MDC9JFAvODJizszN M3zlRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MEi4OFI2Lz5zMkC4PFQzPTxxYU6=
P388 MV;DfZRwfG:6aXPpeJkh[XO|YYm= MXi3NkBp NVzWPXo3UUN3MDC9JFAvODJizszN MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjB6OESyOUc,OTJyOEi0NlU9N2F-
LNCAP M3TmVmN6fG:2b4jpZ4l1gSCjc4PhfS=> MXm3NkBp MmDrTWM2OCB;IECuNFIh|ryP MmTPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJyOEi0NlUoRjF{MEi4OFI2RC:jPh?=
KB M1fLR2N6fG:2b4jpZ4l1gSCjc4PhfS=> NHW2XlA4OiCq NGfERmxKSzVyIE2gNE4xOiEQvF2= M2D0R|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MEi4OFI2Lz5zMkC4PFQzPTxxYU6=
Col2 NXHJV2tSS3m2b4TvfIlkcXS7IHHzd4F6 MY[3NkBp MoHJTWM2OCB;IECuNFIh|ryP MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjB6OESyOUc,OTJyOEi0NlU9N2F-
BC1 NYfDVFJRS3m2b4TvfIlkcXS7IHHzd4F6 M3fKeFczKGh? MYTJR|UxKD1iMD6wNkDPxE1? NVW2SIlvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKwPFg1OjVpPkGyNFg5PDJ3PD;hQi=>
SK-MEL-2 M2\1SGN6fG:2b4jpZ4l1gSCjc4PhfS=> MlvGO|IhcA>? NU[x[HJDUUN3MDC9JFAvODdizszN MnL3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJyOEi0NlUoRjF{MEi4OFI2RC:jPh?=
L2987 MV7DfZRwfG:6aXPpeJkh[XO|YYm= MWjJR|UxKD1iMD6yJO69VQ>? NHTLcms9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkS0N|c5Oyd-MUK0OFM4QDN:L3G+
colon adenocarcinoma RKO NEnsPVdEgXSxdH;4bYNqfHliYYPzZZk> MY\JR|UxKD1iMD6wNUDPxE1? MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjh3Mke2PEc,OTJ6NUK3Olg9N2F-
NCI-H460 M3K5PGN6fG:2b4jpZ4l1gSCjc4PhfS=> MlHoOFghcA>? NHzPdXVKSzVyIE2gNE4xODl3IN88US=> NFvFeVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNE[5OVc6QCd-MUS2PVU4QTh:L3G+
MCF7 NWrtN5ptS3m2b4TvfIlkcXS7IHHzd4F6 M3;Nd|Q5KGh? NITzPJRKSzVyIE2gNE4xOTF{IN88US=> M{P2b|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF2Nkm1O|k5Lz5zNE[5OVc6QDxxYU6=
SF268 NUDUc4c1S3m2b4TvfIlkcXS7IHHzd4F6 NXP3[YloPDhiaB?= MX\JR|UxKD1iMD6wNlE4KM7:TR?= MmPWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR4OUW3PVgoRjF2Nkm1O|k5RC:jPh?=
MDA-MB-231 NEXNSFBEgXSxdH;4bYNqfHliYYPzZZk> NEfVe3g1QCCq M3m5bGlEPTBiPTCwMlAxPDVizszN MmXvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR7OEewOVEoRjF2OUi3NFUyRC:jPh?=
MCF7 MWnDfZRwfG:6aXPpeJkh[XO|YYm= MmXDOFghcA>? NHqxTlBKSzVyIE2gNE4xODR7IN88US=> MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDl6N{C1NUc,OTR7OEewOVE9N2F-
A2780 M4HQXGN6fG:2b4jpZ4l1gSCjc4PhfS=> NE[1N3Y1QCCq MknQTWM2OCB;IECuNFI2KM7:TR?= NEi3NXo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEm4O|A2OSd-MUS5PFcxPTF:L3G+
PC3 NWjTTmg1S3m2b4TvfIlkcXS7IHHzd4F6 NF[wbo01QCCq NUj2cpZMUUN3MDC9JFAvODd5IN88US=> MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDl6N{C1NUc,OTR7OEewOVE9N2F-
MCF7 NG\vWG5EgXSxdH;4bYNqfHliYYPzZZk> NU\GO2NSPzJiaB?= MnHJTWM2OCB;IECuNFAyPCEQvF2= NVLRZZhkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUS5PFcxPTZpPkG0PVg4ODV4PD;hQi=>
multidrug-resistant MCF7 M{HYfmN6fG:2b4jpZ4l1gSCjc4PhfS=> NFPUN4c4OiCq MUPJR|UxKD1iMD6zOVQh|ryP MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDl6N{C1Okc,OTR7OEewOVY9N2F-
PC3 NHf1WIxEgXSxdH;4bYNqfHliYYPzZZk> NVf0bZR7PDhiaB?= M17L[mlEPTBiPTCwMlAyPiEQvF2= M1XUSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3MESzOFAzLz5zNUC0N|QxOjxxYU6=
Hep3B NG\ONndEgXSxdH;4bYNqfHliYYPzZZk> NYPiZYZQPDhiaB?= MlPvTWM2OCB;IECuNFMyKM7:TR?= MkHmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTVyNEO0NFIoRjF3MESzOFAzRC:jPh?=
NCI-H460 MXXDfZRwfG:6aXPpeJkh[XO|YYm= NUHZVpFmPDhiaB?= MU\JR|UxKD1iMD6wNFk2KM7:TR?= Ml3DQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTVyNEO0NFQoRjF3MESzOFA1RC:jPh?=
MCF7 M{TufmN6fG:2b4jpZ4l1gSCjc4PhfS=> Mlm1OFghcA>? NH7qdYFKSzVyIE2gNE4xOTF{IN88US=> MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwOEc,OTVyNEO0NFQ9N2F-
SF268 M1rwTWN6fG:2b4jpZ4l1gSCjc4PhfS=> MYe0PEBp NHjTVHVKSzVyIE2gNE4xOjF5IN88US=> M4TkUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3MESzOFA1Lz5zNUC0N|QxPDxxYU6=
KB MYnDfZRwfG:6aXPpeJkh[XO|YYm= NVvrNGlETUR3MDC9JFAvODByNDFOwG0> MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwO{c,OTVyNEO0NFc9N2F-
Lu1 NIHRcJdEgXSxdH;4bYNqfHliYYPzZZk> MkTISWQ2OCB;IECuNFAzKM7:TR?= MkC3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTVyNEO0NFcoRjF3MESzOFA4RC:jPh?=
LNCAP M{\5V2N6fG:2b4jpZ4l1gSCjc4PhfS=> M{TsTGVFPTBiPTCwMlAxPSEQvF2= NH2xWY49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUC0N|QxPyd-MUWwOFM1ODd:L3G+
RPE1 NFvjd3FEgXSxdH;4bYNqfHliYYPzZZk> M{DmVWVFPTBiPTCwMlAzOyEQvF2= MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwO{c,OTVyNEO0NFc9N2F-
Col2 NYDNfHlvS3m2b4TvfIlkcXS7IHHzd4F6 NIK1W49GTDVyIE2gNE4xPDZizszN MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwO{c,OTVyNEO0NFc9N2F-
T47D M2X2e2Fxd3C2b4Ppd{Bie3OjeR?= MXOyOEBp MWrFR|UxKD1iMD6wN{DPxE1? NVL0RWV{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW1OlY{ODBpPkG1OVY3OzByPD;hQi=>
DLD1 MluxRZBweHSxc3nzJIF{e2G7 NFrvXJYzPCCq Mom1SWM2OCB;IECuNFc2KM7:TR?= NWj0NIk3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW1OlY{ODBpPkG1OVY3OzByPD;hQi=>
H1299 MUXBdI9xfG:|aYOgZZN{[Xl? MVqyOEBp NIjjcHZGSzVyIE2gNE4yPjNizszN MnvwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV3Nk[zNFAoRjF3NU[2N|AxRC:jPh?=
VA13 NYHHboV2S3m2b4TvfIlkcXS7IHHzd4F6 NF\heGs1QCCq MVXJR|UxKD1iMD6wNFUh|ryP Mn\pQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5M{CyOFMoRjF3N{OwNlQ{RC:jPh?=
WI 38 MlvxR5l1d3SxeHnjbZR6KGG|c3H5 MX20PEBp MXzJR|UxKD1iMD6wOEDPxE1? NID5WXg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUezNFI1Oyd-MUW3N|AzPDN:L3G+
Hep G2 NUn6PVVmS3m2b4TvfIlkcXS7IHHzd4F6 MoGzOFghcA>? M2PSXGlEPTBiPTC4MlEh|ryP NX;kZpZwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3N|AzPDNpPkG1O|MxOjR|PD;hQi=>
A549 M1K4TmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVTqZYo1PDhiaB?= NULqTXViUUN3MDC9JFEvOjVizszN M2\ERlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{i3OFYxLz5zNUe4O|Q3ODxxYU6=
SKOV3 NEjTNVNEgXSxdH;4bYNqfHliYYPzZZk> MYS0PEBp NVf0WVA{UUN3MDC9JFEvOzVizszN MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd6N{S2NEc,OTV5OEe0OlA9N2F-
KB NYrZW|EyS3m2b4TvfIlkcXS7IHHzd4F6 MUKzJIRigXN? MlL3TWM2OCB;IECuNFAyKM7:TR?= M3PhbVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4MEO4OVQ2Lz5zNkCzPFU1PTxxYU6=
1A9 M{Lh[2N6fG:2b4jpZ4l1gSCjc4PhfS=> M2\p[FMh\GG7cx?= M4\LSWlEPTBiPTCwMlAxOiEQvF2= NUGwXmRzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[wN|g2PDVpPkG2NFM5PTR3PD;hQi=>
HCT8 MmTPR5l1d3SxeHnjbZR6KGG|c3H5 MnHMN{Bl[Xm| NH7HN|FKSzVyIE2gNE4xOTNizszN M{LZc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4MEO4OVQ2Lz5zNkCzPFU1PTxxYU6=
A431 NYrFT4ZDS2WubDDjfYNt\SCjcoLld5Qh[XO|YYm= MlziSWM2OCB;IECuNFA6KM7:TR?= NFnDOZM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkO3O|E5Pyd-MU[zO|cyQDd:L3G+
VA13 MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1KzVFQ5KGh? MYXJR|UxKD1iMD6wNFQ{KM7:TR?= MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjR7OUOyNkc,OTZ2OUmzNlI9N2F-
WI38 M{\zOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUHkbIFiPDhiaB?= MWjJR|UxKD1iMD6wN|Qh|ryP MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjR7OUOyNkc,OTZ2OUmzNlI9N2F-
HepG2 NULCbXl{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlO2OFghcA>? NHm2NFZKSzVyIE2gOk46KM7:TR?= M3mweFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NEm5N|IzLz5zNkS5PVMzOjxxYU6=
Aro NVfDVIZ7S3m2b4TvfIlkcXS7IHHzd4F6 MmTQTWM2OCB;IECuNFAxOiEQvF2= NWfxUVlHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
PT45 MYXDfZRwfG:6aXPpeJkh[XO|YYm= Mn7CTWM2OCB;IECuNFA2KM7:TR?= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV|OUO3O{c,OTZ3M{mzO|c9N2F-
A549 NEW3VZZEgXSxdH;4bYNqfHliYYPzZZk> MWLJR|UxKD1iMD6wNFYh|ryP M1TCNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
MCF7 MlnNR5l1d3SxeHnjbZR6KGG|c3H5 Mk\UTWM2OCB;IECuNFA4KM7:TR?= Mlf2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
HeLa NID6NYVEgXSxdH;4bYNqfHliYYPzZZk> MYnJR|UxKD1iMD6wNFgh|ryP MofyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
Ovcar3 NV;OTWxNS3m2b4TvfIlkcXS7IHHzd4F6 NVXoblF1UUN3MDC9JFAvODFizszN MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV|OUO3O{c,OTZ3M{mzO|c9N2F-
HT29 NXfGNWY4S3m2b4TvfIlkcXS7IHHzd4F6 M3\nO2lEPTBiPTCwMlA2KM7:TR?= MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV|OUO3O{c,OTZ3M{mzO|c9N2F-
H295R MVLDfZRwfG:6aXPpeJkh[XO|YYm= MYTJR|UxKD1iMD6wPEDPxE1? NInwNVI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
BNL M3raeGN6fG:2b4jpZ4l1gSCjc4PhfS=> M1vYbGlEPTBiPTCwMlIh|ryP M13UPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
4T1 MYjDfZRwfG:6aXPpeJkh[XO|YYm= MXnJR|UxKD1iMD6yJO69VQ>? Mn72QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
HepG2 M136VWN6fG:2b4jpZ4l1gSCjc4PhfS=> MWnJR|UxKD1iMD6zJO69VQ>? M13FUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
U937 GTB Mlj3R5l1d3SxeHnjbZR6KGG|c3H5 MkS5O|IhcA>? NVjFdmN1UUN3MDC9JFAvODB3OTFOwG0> NIHrSZo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkW2Nlg1OCd-MU[1OlI5PDB:L3G+
RPMI 8226/s NVjJTYdlS3m2b4TvfIlkcXS7IHHzd4F6 NVexVnFNPzJiaB?= Mmm4TWM2OCB;IECuNFA4KM7:TR?= MlPwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3NkK4OFAoRjF4NU[yPFQxRC:jPh?=
CEM/s MkL0R5l1d3SxeHnjbZR6KGG|c3H5 M1jCPFczKGh? NYPkfXE3UUN3MDC9JFAvODB5IN88US=> M2fwVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NU[yPFQxLz5zNkW2Nlg1ODxxYU6=
VA13 M2np[GN6fG:2b4jpZ4l1gSCjc4PhfS=> MknMTWM2OCB;IECuNFA2QSEQvF2= M2XiUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4N{K0PFQzLz5zNkeyOFg1OjxxYU6=
WI38 M1m4fWN6fG:2b4jpZ4l1gSCjc4PhfS=> NFW0XGNKSzVyIE2gNE4xPDZ6IN88US=> NEXzWm49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkeyOFg1Oid-MU[3NlQ5PDJ:L3G+
HepG2 M17IS2N6fG:2b4jpZ4l1gSCjc4PhfS=> MUjJR|UxKD1iOT60PUDPxE1? M1PCXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4N{K0PFQzLz5zNkeyOFg1OjxxYU6=
HT29 NXT2SIkyS3m2b4TvfIlkcXS7IHHzd4F6 Mk\XSWM2OCB;IECuNFA3KM7:TR?= NFzBOmg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNki3NFQzQCd-MU[4O|A1Ojh:L3G+
K562 NGO0eZFEgXSxdH;4bYNqfHliYYPzZZk> MX\FR|UxKD1iMD6wNVQh|ryP NV3PSYJlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[4O|A1OjhpPkG2PFcxPDJ6PD;hQi=>
MCF7 M2LzcmN6fG:2b4jpZ4l1gSCjc4PhfS=> MXjFR|UxKD1iMD6wN|Yh|ryP NW\HSnI5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[4O|A1OjhpPkG2PFcxPDJ6PD;hQi=>
VA-13 M33vWGN6fG:2b4jpZ4l1gSCjc4PhfS=> M2nDNGlEPTBiPTCwMlAxPSEQvF2= M3THc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4OUOzPFY5Lz5zNkmzN|g3QDxxYU6=
WI38 M1jLb2N6fG:2b4jpZ4l1gSCjc4PhfS=> NG\XPYxKSzVyIE2gNE4xPCEQvF2= NVHEboZPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[5N|M5PjhpPkG2PVM{QDZ6PD;hQi=>
VA13 M4[5dmN6fG:2b4jpZ4l1gSCjc4PhfS=> NW[wfJZ[UUN3MDC9JFAvODB3IN88US=> MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzB4N{G1OUc,OTdyNkexOVU9N2F-
WI38 NGnGXnJEgXSxdH;4bYNqfHliYYPzZZk> MXPJR|UxKD1iMD6wOEDPxE1? NHXNV489[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{C2O|E2PSd-MUewOlcyPTV:L3G+
Hep G2 NIewU2VEgXSxdH;4bYNqfHliYYPzZZk> MnfVTWM2OCB;IEiuNUDPxE1? NWjqO|ZYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUewOlcyPTVpPkG3NFY4OTV3PD;hQi=>
TW01 MlXvR5l1d3SxeHnjbZR6KGG|c3H5 MkHlTWM2OCB;IECuNFAxOyEQvF2= MnzZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzMUOyPFgoRjF5MUGzNlg5RC:jPh?=
MCF7 M1rjRWN6fG:2b4jpZ4l1gSCjc4PhfS=> M{PocWlEPTBiPTCwMlAxODVizszN M3O5dlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
MKN45 M3nxVWN6fG:2b4jpZ4l1gSCjc4PhfS=> MW\JR|UxKD1iMD6wNFA2KM7:TR?= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzFzM{K4PEc,OTdzMUOyPFg9N2F-
MES-SA MYnDfZRwfG:6aXPpeJkh[XO|YYm= NH;HNZBKSzVyIE2gNE4xODB3IN88US=> M4C3b|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
HCT116 M13NVWN6fG:2b4jpZ4l1gSCjc4PhfS=> Ml;TTWM2OCB;IECuNFAxPiEQvF2= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzFzM{K4PEc,OTdzMUOyPFg9N2F-
RPTEC NXHEWXR{S3m2b4TvfIlkcXS7IHHzd4F6 NIPZd4FKSzVyIE2gNE4xODB7IN88US=> NH;ITHQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{GxN|I5QCd-MUexNVMzQDh:L3G+
Hep3B MmTKR5l1d3SxeHnjbZR6KGG|c3H5 NW\RPFB4UUN3MDC9JFAvODB3NDFOwG0> M2XrWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
NCI-H226 M1PkSWN6fG:2b4jpZ4l1gSCjc4PhfS=> MXHJR|UxKD1iMD6wNFY5KM7:TR?= M2q5NlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
A498 MUfDfZRwfG:6aXPpeJkh[XO|YYm= MnXTTWM2OCB;IECuNFYyKM7:TR?= NGi1Nlk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{GxN|I5QCd-MUexNVMzQDh:L3G+
MDA435/LCC6 MVrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NEnKTG9KSzVyIE2gNE4xODJ7IN88US=> NYHTZ|FiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexOVQ2ODVpPkG3NVU1PTB3PD;hQi=>
multidrug resistant MDA435/LCC6 M{WwPGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NVPCW3Q4UUN3MDC9JFAvODB2ODFOwG0> M1jXVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUW0OVA2Lz5zN{G1OFUxPTxxYU6=
P388 MlLLRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MYPJR|UxKD1iMD6wNlIh|ryP MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF3NEWwOUc,OTdzNUS1NFU9N2F-
adriamycin resistant P388 MoDNRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? Mnz5TWM2OCB;IECuNFMh|ryP NHeybpU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G1OFUxPSd-MUexOVQ2ODV:L3G+
LT12 M{Hqb2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MmHtOFghcA>? Ml30TWM2OCB;IECuNFA3KM7:TR?= MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
SKOV3 NELzU2JCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NF;6O2w1QCCq NWrxVldmUUN3MDC9JFAvODFizszN NF7VeFM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G4NVE3PCd-MUexPFEyPjR:L3G+
NCI-H460 MkXKRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M3r3R|Q5KGh? Ml3uTWM2OCB;IECuNFEh|ryP MmPkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzOEGxOlQoRjF5MUixNVY1RC:jPh?=
SF268 NInuTm9CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NY\KT4lFPDhiaB?= M4LweGlEPTBiPTCwMlAyKM7:TR?= MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
RKO NEjpRmNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MX20PEBp M36zTWlEPTBiPTCwMlAyKM7:TR?= NYLJOFFDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
KB/HeLa M3T6cWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NXS2e4tlPDhiaB?= M{faS2lEPTBiPTCwMlAyKM7:TR?= MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
P388 M4Wxe2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MmPWOFghcA>? M3LCbmlEPTBiPTCwMlA1KM7:TR?= MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
L1210 NVLtS5EySW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M3HIbVQ5KGh? NHnEemlKSzVyIE2gNE4xPiEQvF2= Ml3ZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzOEGxOlQoRjF5MUixNVY1RC:jPh?=
LT12 MDR NWnOfIZOSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MnG4OFghcA>? MkDKTWM2OCB;IECuOEDPxE1? M3;ZSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUixNVY1Lz5zN{G4NVE3PDxxYU6=
A2780 NVXHSWVuS3m2b4TvfIlkcXS7IHHzd4F6 MWDJR|UxKD1iMD6wNFEh|ryP MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzJyNkGzPUc,OTd{ME[xN|k9N2F-
A2780-1A9 NHPxc3BEgXSxdH;4bYNqfHliYYPzZZk> MofiTWM2OCB;IECuNFAyOSEQvF2= MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzJyNkGzPUc,OTd{ME[xN|k9N2F-
A549 NWLadGpFS3m2b4TvfIlkcXS7IHHzd4F6 NETaTpNKSzVyIE2gNE4xODN4IN88US=> NVLBRoZJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyNFYyOzlpPkG3NlA3OTN7PD;hQi=>
1A9PTX22 NXPmR5F1S3m2b4TvfIlkcXS7IHHzd4F6 MoHBTWM2OCB;IECuNFE6KM7:TR?= NUjLZ5Y2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyNFYyOzlpPkG3NlA3OTN7PD;hQi=>
1A9PTX10 Ml7BR5l1d3SxeHnjbZR6KGG|c3H5 MoXLTWM2OCB;IECuNFMh|ryP NFfnW2I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KwOlE{QSd-MUeyNFYyOzl:L3G+
A2780AD M1fZVWN6fG:2b4jpZ4l1gSCjc4PhfS=> M2jTRWlEPTBiPTCwMlkh|ryP MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzJyNkGzPUc,OTd{ME[xN|k9N2F-
KB MUDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NEHwTFNKSzVyIE2gNE4xODJ2NTFOwG0> NFq4T2o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KyPFg4Oyd-MUeyNlg5PzN:L3G+
COLO205 M3XoS2N6fG:2b4jpZ4l1gSCjc4PhfS=> M3ewbmlEPTBiPTCwMlAxOzNizszN NIflc4Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KyPFg4Oyd-MUeyNlg5PzN:L3G+
KB8.5 NGPKVWdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M{nhfWlEPTBiPTCwMlAzPiEQvF2= NX;FN4ZvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyNlg5PzNpPkG3NlI5QDd|PD;hQi=>
KBV1 MYLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MorvTWM2OCB;IEKuNFE{KM7:TR?= MkG1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{Mki4O|MoRjF5MkK4PFc{RC:jPh?=
A2780 NXXZO257S3m2b4TvfIlkcXS7IHHzd4F6 MoDmTWM2OCB;IECuNFAxPyEQvF2= NVLWWG5lRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyN|k2QTdpPkG3NlM6PTl5PD;hQi=>
2780AD MWfDfZRwfG:6aXPpeJkh[XO|YYm= M{[3VGlEPTBiPTCwMlU{PSEQvF2= NWTTUm5RRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyN|k2QTdpPkG3NlM6PTl5PD;hQi=>
1A9 NIL3UoNEgXSxdH;4bYNqfHliYYPzZZk> NYTKO2tDTUR3MDC9JFAvODBzIN88US=> NWPUSm86RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
MCF7 NWnlVVdVS3m2b4TvfIlkcXS7IHHzd4F6 MX\FSFUxKD1iMD6wNFEyKM7:TR?= MlyxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd|NUC4N|QoRjF5M{WwPFM1RC:jPh?=
DU145 MmL2R5l1d3SxeHnjbZR6KGG|c3H5 NGfrZ|JGTDVyIE2gNE4xODF|IN88US=> M3zBb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
KB M3;XSWN6fG:2b4jpZ4l1gSCjc4PhfS=> MVXFSFUxKD1iMD6wNFE5KM7:TR?= NUDHblk6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
A549 NX3aeYJKS3m2b4TvfIlkcXS7IHHzd4F6 NVTuV21{TUR3MDC9JFAvODB{MzFOwG0> NVn1NWhORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
LNCAP Mn7JR5l1d3SxeHnjbZR6KGG|c3H5 NH\LSXlGTDVyIE2gNE4xODJ4IN88US=> M1W4blxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
PC3 MoXMR5l1d3SxeHnjbZR6KGG|c3H5 NUD6TmpDTUR3MDC9JFAvODV3NTFOwG0> M1nnXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
KBVIN M{X1eWN6fG:2b4jpZ4l1gSCjc4PhfS=> MWPFSFUxKD1iMD6zNVEh|ryP MljhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd|NUC4N|QoRjF5M{WwPFM1RC:jPh?=
A2780 NYf2[nViS3m2b4TvfIlkcXS7IHHzd4F6 M1;XUmlEPTBiPTCwMlAxOTZizszN NH3vUpI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{O5OVQ3PSd-MUezPVU1PjV:L3G+
A2780/AD M2jtdmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVTXb3FFUUN3MDC9JFAvQTJizszN M2PGR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{m1OFY2Lz5zN{O5OVQ3PTxxYU6=
KB MVTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NXHTWWVjUUN3MDC9JFAvODB{NEWg{txO NWn1eGg1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVY2OjRpPkG3OFE3PTJ2PD;hQi=>
COLO205 M1L4bmN6fG:2b4jpZ4l1gSCjc4PhfS=> NWHLZmVjUUN3MDC9JFAvODB|MzFOwG0> NV\GSoxNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVY2OjRpPkG3OFE3PTJ2PD;hQi=>
KB8.5 NUnsdnpxSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NXzwO3NTUUN3MDC9JFAvODJ4IN88US=> MlvkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MU[1NlQoRjF5NEG2OVI1RC:jPh?=
KBV1 MVXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M{PzdWlEPTBiPTCyMlAyOyEQvF2= NUH2dXhuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVY2OjRpPkG3OFE3PTJ2PD;hQi=>
neural precursor NIKxZW1CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NHrvNndGSzVyIE2gNE4xOSEQvF2= NE[xc3c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxO|Y{OSd-MUe0NVc3OzF:L3G+
OVCAR-3 NGnC[INEgXSxdH;4bYNqfHliYYPzZZk> NYL4XpdwUUN3MDC9JFAvODByMjFOwG0> MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzRzOUC2OUc,OTd2MUmwOlU9N2F-
MDA-MB-231 MVrDfZRwfG:6aXPpeJkh[XO|YYm= MnjBTWM2OCB;IECuNFA1PSEQvF2= M3;SOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
MCF7 MnPXR5l1d3SxeHnjbZR6KGG|c3H5 MYHJR|UxKD1iMD6wNFQ6KM7:TR?= NIT4UIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxPVA3PSd-MUe0NVkxPjV:L3G+
NCI-H1299 M4W1ZWN6fG:2b4jpZ4l1gSCjc4PhfS=> MX65OkBp MnTiTWM2OCB;IECuNFE2KM7:TR?= NUDjSWllRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVkxPjVpPkG3OFE6ODZ3PD;hQi=>
A2780 M3;KXmN6fG:2b4jpZ4l1gSCjc4PhfS=> NFjJTXVKSzVyIE2gNE4xOjVizszN NHPUUJc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxPVA3PSd-MUe0NVkxPjV:L3G+
PC3 MW\DfZRwfG:6aXPpeJkh[XO|YYm= NVjWU4pEUUN3MDC9JFAvODd5IN88US=> MkjwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MUmwOlUoRjF5NEG5NFY2RC:jPh?=
LoVo NWSx[ZJRS3m2b4TvfIlkcXS7IHHzd4F6 NHmwepVKSzVyIE2gNE4xQSEQvF2= NYDXR4VFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVkxPjVpPkG3OFE6ODZ3PD;hQi=>
L2987 M{e2fGN6fG:2b4jpZ4l1gSCjc4PhfS=> MnLuTWM2OCB;IECuNkDPxE1? NF\zPHQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxPVA3PSd-MUe0NVkxPjV:L3G+
cells NIjyWJREgXSxdH;4bYNqfHliYYPzZZk> Mn7LTWM2OCB;IECuNFA2QSEQvF2= MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR2MkW3O{c,OTd2NEK1O|c9N2F-
cells MUDDfZRwfG:6aXPpeJkh[XO|YYm= MnnMTWM2OCB;IECuNFEh|ryP NF7OdXk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S4OVIxPyd-MUe0PFUzODd:L3G+
A2780 M1nEVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWHJR|UxKD1iMD6wNFI5KM7:TR?= MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR7MEi3PEc,OTd2OUC4O|g9N2F-
VA13 M17Qcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXjpcpFGUUN3MDC9JFAvODB3IN88US=> NFHnPIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S5NFg4QCd-MUe0PVA5Pzh:L3G+
WI38 NIi4WJNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmmwTWM2OCB;IECuNFQh|ryP NVzSbZRCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0PVA5PzhpPkG3OFkxQDd6PD;hQi=>
2780AD NEG0O4tIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MY\JR|UxKD1iMD6xPFMh|ryP MmS5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUC4O|goRjF5NEmwPFc5RC:jPh?=
HepG2 NHzKbo5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFvXbWlKSzVyIE2gPE4yKM7:TR?= NIfYeWU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S5NFg4QCd-MUe0PVA5Pzh:L3G+
HT29 MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlLKOFghcA>? M{fIW2dKPTBiPTCwMlAyPSEQvF2= NFn2c5Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S5PFk3OCd-MUe0PVg6PjB:L3G+
M21 MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4DkcVQ5KGh? NI\yVZNIUTVyIE2gNE4xOzdizszN NFXyfI89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S5PFk3OCd-MUe0PVg6PjB:L3G+
MCF7 M13UW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn[1OFghcA>? MUPHTVUxKD1iMD6wOVQh|ryP M3H0clxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEm4PVYxLz5zN{S5PFk3ODxxYU6=
1A9 Mme5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVW3NkBp NUf6Vo9sT0l3MDC9JFAvODByN{Gg{txO MmjXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEK1O|IoRjF5NUSyOVczRC:jPh?=
1A9/Ptx22 NVTGNlV{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NU\GSZZOPzJiaB?= NU\6TplUT0l3MDC9JFAvODVzIN88US=> MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV2MkW3Nkc,OTd3NEK1O|I9N2F-
1A9/Ptx10 NVe1bmU3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVm3NkBp M3zyfWdKPTBiPTCwMlA3PCEQvF2= MkW4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEK1O|IoRjF5NUSyOVczRC:jPh?=
cells expressing MRP1 MlXuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmPnTWM2OCB;IECuNFAzPSEQvF2= NULUdZk6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1OlcyOjFpPkG3OVY4OTJzPD;hQi=>
cells expressing Pgp/MRP1 NGLNOHRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NELDOWdKSzVyIE2gNk44KM7:TR?= Mn7zQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NkexNlEoRjF5NU[3NVIyRC:jPh?=
VA13 Mnr4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGLPcY1KSzVyIE2gOUDPxE1? NE\nWG89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W5OVE{PCd-MUe1PVUyOzR:L3G+
MCF7 Mn71SpVv[3Srb36gZZN{[Xl? MmfiTWM2OCB;IECuNFAyQCEQvF2= NETGRZM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[wNVc{QSd-MUe2NFE4Ozl:L3G+
adriamycin-resistant MCF7 NGfZc49HfW6ldHnvckBie3OjeR?= M3;qOmlEPTBiPTC4MlIh|ryP MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZyMUezPUc,OTd4MEG3N|k9N2F-
RPMI8226 M3z3Z2N6fG:2b4jpZ4l1gSCjc4PhfS=> MUHHTVUxKD1iMD6wNFIh|ryP MonJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
HT29 MXHDfZRwfG:6aXPpeJkh[XO|YYm= NVnmRVJvT0l3MDC9JFAvODB{IN88US=> MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7NkOzNkc,OTd4OU[zN|I9N2F-
COLO205 MYPDfZRwfG:6aXPpeJkh[XO|YYm= MYjHTVUxKD1iMD6wNFMh|ryP MnW1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
HCC2998 MXHDfZRwfG:6aXPpeJkh[XO|YYm= M3\3XWdKPTBiPTCwMlAxOyEQvF2= MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7NkOzNkc,OTd4OU[zN|I9N2F-
HS578T M2T0OWN6fG:2b4jpZ4l1gSCjc4PhfS=> MmjhS2k2OCB;IECuNFA{KM7:TR?= M4DMTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
PC3 MVLDfZRwfG:6aXPpeJkh[XO|YYm= NVjVZ4dOT0l3MDC9JFAvODB2IN88US=> NUDtT5hGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
SNB75 MnXwR5l1d3SxeHnjbZR6KGG|c3H5 MlvxS2k2OCB;IECuNFA1KM7:TR?= MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7NkOzNkc,OTd4OU[zN|I9N2F-
A549 MlfzR5l1d3SxeHnjbZR6KGG|c3H5 NVHSU|JIT0l3MDC9JFAvODB2IN88US=> M37hbVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
KM12 NYfIRllwS3m2b4TvfIlkcXS7IHHzd4F6 MUTHTVUxKD1iMD6wNFQh|ryP M4nCZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
DU145 MlvIR5l1d3SxeHnjbZR6KGG|c3H5 Mo\QS2k2OCB;IECuNFA2KM7:TR?= NGDEZZk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
SK-OV3 Mm[wR5l1d3SxeHnjbZR6KGG|c3H5 NELkUFhIUTVyIE2gNE4xODhizszN MkPOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
NCI-H322M NVHhR4JGS3m2b4TvfIlkcXS7IHHzd4F6 MX7HTVUxKD1iMD6wNVMh|ryP MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7NkOzNkc,OTd4OU[zN|I9N2F-
UACC257 M3\i[2N6fG:2b4jpZ4l1gSCjc4PhfS=> NW\4[HkxT0l3MDC9JFAvODRizszN M3LNdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
HCT15 NHjDfVdEgXSxdH;4bYNqfHliYYPzZZk> NEnO[nlIUTVyIE2gNE4yPThizszN NGPHZWo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
ACHN M2rv[WN6fG:2b4jpZ4l1gSCjc4PhfS=> MUHHTVUxKD1iMD6zPVgh|ryP MlrqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
HeLa NIT3UldEgXSxdH;4bYNqfHliYYPzZZk> M{\3S2lEPTBiPTCwMlAxPTZizszN NIjKXFY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{e2OFE1QCd-MUe3OlQyPDh:L3G+
MCF7 NFvsOlVEgXSxdH;4bYNqfHliYYPzZZk> Mn7ETWM2OCB;IECuNFEzPCEQvF2= M3zmbVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5N{[0NVQ5Lz5zN{e2OFE1QDxxYU6=
A549 MUHDfZRwfG:6aXPpeJkh[XO|YYm= MnrnTWM2OCB;IECuNFEzPiEQvF2= M{nzfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5N{[0NVQ5Lz5zN{e2OFE1QDxxYU6=
HGC27 NXjmR3RuS3m2b4TvfIlkcXS7IHHzd4F6 NHK2c|hKSzVyIE2gNE44Pzd6IN88US=> MmixQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd5NkSxOFgoRjF5N{[0NVQ5RC:jPh?=
HL60 NIK1ZpBEgXSxdH;4bYNqfHliYYPzZZk> NV\EdGR4PzJiaB?= NFHKUYFKSzVyIE2gNE46OyEQvF2= M13XR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OEm2PFE3Lz5zN{i5OlgyPjxxYU6=
P388 M{HxfGN6fG:2b4jpZ4l1gSCjc4PhfS=> M1KyelczKGh? NGP0WVBKSzVyIE2gNE46OyEQvF2= NHHaZZM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{i5OlgyPid-MUe4PVY5OTZ:L3G+
BEL-7402 M{WxcGN6fG:2b4jpZ4l1gSCjc4PhfS=> NGL2cpUzPCCq NFjFS5JKSzVyIE2gNE46OyEQvF2= M3Tq[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OEm2PFE3Lz5zN{i5OlgyPjxxYU6=
A459 MmLPR5l1d3SxeHnjbZR6KGG|c3H5 MY[yOEBp M4\oOmlEPTBiPTCwMlk{KM7:TR?= NWD2VXNPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe4PVY5OTZpPkG3PFk3QDF4PD;hQi=>
HeLa MVzDfZRwfG:6aXPpeJkh[XO|YYm= NX\zcXR2UUN3MDC9JFAvODJizszN MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzMUCxO{c,OTd7MUGwNVc9N2F-
HepG2 M37h[GN6fG:2b4jpZ4l1gSCjc4PhfS=> MVHJR|UxKD1iMD64NkDPxE1? M{LwRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUGxNFE4Lz5zN{mxNVAyPzxxYU6=
BGC823 MUHDfZRwfG:6aXPpeJkh[XO|YYm= NHL2RWNKSzVyIE2gNU4yPSEQvF2= Mn3yQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7MUGwNVcoRjF5OUGxNFE4RC:jPh?=
Aro MYHDfZRwfG:6aXPpeJkh[XO|YYm= NXvEd2Z3PzJiaB?= MYPJR|UxKD1iMD6wNFAzKM7:TR?= MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
PT45 MXrDfZRwfG:6aXPpeJkh[XO|YYm= MUS3NkBp MoLZTWM2OCB;IECuNFA2KM7:TR?= M3XnVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUG1PFUyLz5zN{mxOVg2OTxxYU6=
A549 NXzHTIJOS3m2b4TvfIlkcXS7IHHzd4F6 M4GyT|czKGh? NYjIU5hwUUN3MDC9JFAvODB4IN88US=> M{XHNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUG1PFUyLz5zN{mxOVg2OTxxYU6=
MCF7 M4SwSGN6fG:2b4jpZ4l1gSCjc4PhfS=> NFXO[lY4OiCq NYrxe2N{UUN3MDC9JFAvODB5IN88US=> MmHuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7MUW4OVEoRjF5OUG1PFUyRC:jPh?=
HeLa NVrY[VYyS3m2b4TvfIlkcXS7IHHzd4F6 MVW3NkBp MoXPTWM2OCB;IECuNFA5KM7:TR?= NEfGfmw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
Ovcar3 M1vOcGN6fG:2b4jpZ4l1gSCjc4PhfS=> NXLjTWsyPzJiaB?= NELDZplKSzVyIE2gNE4xOSEQvF2= MkLnQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7MUW4OVEoRjF5OUG1PFUyRC:jPh?=
HT29 MVHDfZRwfG:6aXPpeJkh[XO|YYm= NVP5NJk{PzJiaB?= M2XIRmlEPTBiPTCwMlA2KM7:TR?= NGTBUpA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
A549T12 M1vydGN6fG:2b4jpZ4l1gSCjc4PhfS=> NXnwO2xrPzJiaB?= M{n5[mlEPTBiPTCwMlA3KM7:TR?= NHq0WpI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
H295R M3XIbmN6fG:2b4jpZ4l1gSCjc4PhfS=> M1LheFczKGh? MUXJR|UxKD1iMD6wPEDPxE1? MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
A549T24 NXXPS2t3S3m2b4TvfIlkcXS7IHHzd4F6 MVi3NkBp Mn7nTWM2OCB;IECuNVAzKM7:TR?= NWCxeox5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5NVU5PTFpPkG3PVE2QDVzPD;hQi=>
OE33 Mne3R5l1d3SxeHnjbZR6KGG|c3H5 NGD3[JA4OiCq NHfRe3JKSzVyIE2gNE4zKM7:TR?= M3rPNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUG1PFUyLz5zN{mxOVg2OTxxYU6=
HepG2 MU\DfZRwfG:6aXPpeJkh[XO|YYm= NUWwbnhtPzJiaB?= Mnf4TWM2OCB;IECuN{DPxE1? NYjUfopoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5NVU5PTFpPkG3PVE2QDVzPD;hQi=>
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L12 M4nQRWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M{WzclQ5KGh? MoT1TWM2OCB;IECuNFA3KM7:TR?= NFzVfXM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{m3N|M3OSd-MUe5O|M{PjF:L3G+
NCI-H460 MV3DfZRwfG:6aXPpeJkh[XO|YYm= MmDEOFghcA>? MnjKTWM2OCB;IECuNFEh|ryP MmD4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
SKOV3 MoniR5l1d3SxeHnjbZR6KGG|c3H5 M132XlQ5KGh? Mkm2TWM2OCB;IECuNFEh|ryP MojYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
SF268 Ml:4R5l1d3SxeHnjbZR6KGG|c3H5 M1zOZlQ5KGh? M1vXVWlEPTBiPTCwMlAyKM7:TR?= MlfzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
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KB/HeLa MV7DfZRwfG:6aXPpeJkh[XO|YYm= MWW0PEBp M3HudmlEPTBiPTCwMlAyKM7:TR?= Ml61QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
P388 M2LTXmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NIPBWI81QCCq MkLnTWM2OCB;IECuNFQh|ryP MojsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
cells assessed as accumulation at G2/M phase after 24 hrs by flow cytometric analysis Ml7FR4VtdCCleXPs[UBienKnc4SgZZN{[Xl? NYPWS3U{TUN3MDC9JFAvODR7IN88US=> NIXrd4k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{m3N|M3OSd-MUe5O|M{PjF:L3G+
L1210 NWDFWnpuSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NF3nSo01QCCq NV;6WodMUUN3MDC9JFAvODZizszN MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzl5M{O2NUc,OTd7N{OzOlE9N2F-
cells after 48 hrs by XTT assay M33vTGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M2nmPWlEPTBiPTCwMlQh|ryP MmPzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
A2780 NH25WYNEgXSxdH;4bYNqfHliYYPzZZk> NVzSXFZ5UUN3MDC9JFAvODB4MzFOwG0> MmP0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyMEGwPFcoRjF6MECxNFg4RC:jPh?=
BGC823 MULDfZRwfG:6aXPpeJkh[XO|YYm= MlfGTWM2OCB;IECuNFA4KM7:TR?= MnzyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyMEGwPFcoRjF6MECxNFg4RC:jPh?=
A549 MlPxR5l1d3SxeHnjbZR6KGG|c3H5 MmX0TWM2OCB;IECuNFE6KM7:TR?= NFvYSFY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOECwNVA5Pyd-MUiwNFExQDd:L3G+
HCT8 Mnv0R5l1d3SxeHnjbZR6KGG|c3H5 NWr1RoJtUUN3MDC9JFAvODN5IN88US=> MnXHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyMEGwPFcoRjF6MECxNFg4RC:jPh?=
Bel7402 NYCyXYg5S3m2b4TvfIlkcXS7IHHzd4F6 NG\sbVhKSzVyIE2gNE4yKM7:TR?= NXqwdIRTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiwNFExQDdpPkG4NFAyODh5PD;hQi=>
cells by alamar blue assay MX7GeY5kfGmxbjDhd5NigQ>? MXTJR|UxKD1iMD6wOEDPxE1? NGfuTmw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEC3NFk3PSd-MUiwO|A6PjV:L3G+
PANC1 NVXiVWE5S3m2b4TvfIlkcXS7IHHzd4F6 M2LaN|czKGh? NWf3NoNWUUN3MDC9JFAvODB5IN88US=> Mlr2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyOEGyOVcoRjF6MEixNlU4RC:jPh?=
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AsPC1 MXPDfZRwfG:6aXPpeJkh[XO|YYm= NIHBcXg4OiCq NV;tTHk2UUN3MDC9JFAvODJizszN Mne5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyOEGyOVcoRjF6MEixNlU4RC:jPh?=
NCI/ADR MlP0R5l1d3SxeHnjbZR6KGG|c3H5 MU[3NkBp NGjyZo5KSzVyIE2gNUDPxE1? NYXUNFNYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiwPFEzPTdpPkG4NFgyOjV5PD;hQi=>
SK-BR3 MV7BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MmjWPVYhcA>? MXnHTVUxKD1iNj6xJO69VQ>? NYXaOmZLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUixOlQzODVpPkG4NVY1OjB3PD;hQi=>
A2780 NEPMO|dCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M3HoSVk3KGh? NYnoOmsyUUN3MDC9JFAvODJ|NDFOwG0> NHfPXmI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEG3O|AyPCd-MUixO|cxOTR:L3G+
SNU398 NYXGfIRISXCxcITvd4l{KGG|c3H5 NELFOnIzPCCq MlX0SWM2OCB;IECuNFEyKM7:TR?= MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDF7N{[xOEc,OThzOUe2NVQ9N2F-
HCT116 MXXBdI9xfG:|aYOgZZN{[Xl? NFvFbm8zPCCq M3jXUWVEPTBiPTCwMlAzPCEQvF2= MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDF7N{[xOEc,OThzOUe2NVQ9N2F-
T47D MnfhRZBweHSxc3nzJIF{e2G7 M{DVSVI1KGh? M1XvVGVEPTBiPTCwMlA{PiEQvF2= NVXTdml2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUixPVc3OTRpPkG4NVk4PjF2PD;hQi=>
SJSA1 MlPOR5l1d3SxeHnjbZR6KGG|c3H5 M3XZWlYhcA>? NFP1b|VKSzVyIE2gNE4xODN{IN88US=> NWP3b3A4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiyOFM3QTZpPkG4NlQ{Pjl4PD;hQi=>
P388 MWrDfZRwfG:6aXPpeJkh[XO|YYm= MoLWO|IhcA>? NGDFepdKSzVyIE2gNE46OyEQvF2= MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDJ6MUm1Nkc,OTh{OEG5OVI9N2F-
HL60 NHfLfHNEgXSxdH;4bYNqfHliYYPzZZk> NEHFd2M4OiCq NGTxZYRKSzVyIE2gNE46OyEQvF2= MojrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh{OEG5OVIoRjF6MkixPVUzRC:jPh?=
Bel7402 NWTIR49US3m2b4TvfIlkcXS7IHHzd4F6 NFnpUmYzPCCq NYrOW|l6UUN3MDC9JFAvQTNizszN M37XSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MkixPVUzLz5zOEK4NVk2OjxxYU6=
A549 MlfzR5l1d3SxeHnjbZR6KGG|c3H5 MUeyOEBp M1PGc2lEPTBiPTCwMlk{KM7:TR?= MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDJ6MUm1Nkc,OTh{OEG5OVI9N2F-
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KBV20C M2DiOGN6fG:2b4jpZ4l1gSCjc4PhfS=> MXm0PEBp NI\LcXBKSzVyIE2gNU41PCEQvF2= M3noTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6Mkm1OFkxLz5zOEK5OVQ6ODxxYU6=
DU145 NGG3OFREgXSxdH;4bYNqfHliYYPzZZk> MVy3NkBp Mlr2TWM2OCB;IECuNFA2KM7:TR?= NHnDb2Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOwPFU3Pid-MUizNFg2PjZ:L3G+
HL60 NYnNOpZZS3m2b4TvfIlkcXS7IHHzd4F6 NVzyNHdlPzJiaB?= NHHyb3JKSzVyIE2gNE4xODVizszN NXnXXHpJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUizNFg2PjZpPkG4N|A5PTZ4PD;hQi=>
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MESSA Mnv4R5l1d3SxeHnjbZR6KGG|c3H5 MXq3NkBp M{TucWlEPTBiPTCwMlAxPSEQvF2= MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDNyOEW2Okc,OTh|MEi1OlY9N2F-
P388 NF7QVFhEgXSxdH;4bYNqfHliYYPzZZk> NYn6eHFGPzJiaB?= MoDRTWM2OCB;IECuNFEh|ryP M3TVbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6M{C4OVY3Lz5zOEOwPFU3PjxxYU6=
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MESSA/DX5 NEHaZYVEgXSxdH;4bYNqfHliYYPzZZk> NF7xN244OiCq NEjxZo5KSzVyIE2gOUDPxE1? M4jZ[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6M{C4OVY3Lz5zOEOwPFU3PjxxYU6=
K562 M2jVfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnKzO|IhcA>? NVuxT2sxUUN3MDC9JFAvODByNjFOwG0> MlrxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh|MUOzNFcoRjF6M{GzN|A4RC:jPh?=
KB3-1 M3HlWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX63NkBp NXzWfmJ1UUN3MDC9JFAvODB{IN88US=> NGL3dGo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOxN|MxPyd-MUizNVM{ODd:L3G+
HepG2 M4PiPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVS3NkBp NU\R[JpqUUN3MDC9JFAvODB5IN88US=> NHvERnM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOxN|MxPyd-MUizNVM{ODd:L3G+
KB V1 MnjQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWXzW3BPPzJiaB?= MnX6TWM2OCB;IEig{txO NWjDfotHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUizNVM{ODdpPkG4N|E{OzB5PD;hQi=>
A549 M1HQPWN6fG:2b4jpZ4l1gSCjc4PhfS=> NV\SfnpnOyCmYYnz NHzCRYZKSzVyIE2gNE4xODdizszN M{\MSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEG5NVU1Lz5zOESxPVE2PDxxYU6=
MCF7 MWHDfZRwfG:6aXPpeJkh[XO|YYm= NH76WmM{KGSjeYO= M{jq[WlEPTBiPTCwMlAyOTdizszN M3jTclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEG5NVU1Lz5zOESxPVE2PDxxYU6=
HepG2 NWfDPW42S3m2b4TvfIlkcXS7IHHzd4F6 M3L0eFMh\GG7cx?= M{m3UGlEPTBiPTCwMlA1PjhizszN NHzZS|c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOESxPVE2PCd-MUi0NVkyPTR:L3G+
MDA-MB-231 NHPwd25EgXSxdH;4bYNqfHliYYPzZZk> M{nRPFMh\GG7cx?= M3;5fGlEPTBiPTCwMlA4ODNizszN MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDRzOUG1OEc,OTh2MUmxOVQ9N2F-
Hep3B NED6Z3dEgXSxdH;4bYNqfHliYYPzZZk> NVHufI01OyCmYYnz MkS5TWM2OCB;IECuNVMh|ryP M3HLb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEG5NVU1Lz5zOESxPVE2PDxxYU6=
CCRF-CEM NV3LWlF2S3m2b4TvfIlkcXS7IHHzd4F6 M4flW|czKGh? MUfJR|UxKD1iMD6wNFEzPzRizszN NEfEZVE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES1NFQ2Pid-MUi0OVA1PTZ:L3G+
HCT116 M2fhfWN6fG:2b4jpZ4l1gSCjc4PhfS=> M3:wOFczKGh? MofTTWM2OCB;IECuNFAyOyEQvF2= MnezQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NUC0OVYoRjF6NEWwOFU3RC:jPh?=
MX1 MX3DfZRwfG:6aXPpeJkh[XO|YYm= M37ZcFczKGh? NHvSSFFKSzVyIE2gNE4xOzVizszN NIq3U|k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES1NFQ2Pid-MUi0OVA1PTZ:L3G+
HeLa NFyxcItCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M4D6UVQ5KGh? NHLibYhKSzVyIE2gNE4xODF3IN88US=> NWTONHFERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0OlE6QTdpPkG4OFYyQTl5PD;hQi=>
HT29 M1fBOmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MWe0PEBp MXnJR|UxKD1iMD6wNFE6KM7:TR?= MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR4MUm5O{c,OTh2NkG5PVc9N2F-
U2OS NVfNd|RWSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MVe0PEBp NFi3cXFKSzVyIE2gNE4xOjRizszN NFT2PYw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES2NVk6Pyd-MUi0OlE6QTd:L3G+
A2780 M{PTSmN6fG:2b4jpZ4l1gSCjc4PhfS=> NETlfpM4OiCq MVrJR|UxKD1iMD6wNFE{QCEQvF2= MonkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NkW4OFYoRjF6NE[1PFQ3RC:jPh?=
MCF7 NGfpVINEgXSxdH;4bYNqfHliYYPzZZk> MX23NkBp M{PtW2lEPTBiPTCwMlAxOTdizszN MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR4NUi0Okc,OTh2NkW4OFY9N2F-
LCC6 NGXQPVlEgXSxdH;4bYNqfHliYYPzZZk> Mlu2O|IhcA>? NH:5dndKSzVyIE2gNE4xODNzIN88US=> MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR4NUi0Okc,OTh2NkW4OFY9N2F-
1A9PTX22 NWPPXYdES3m2b4TvfIlkcXS7IHHzd4F6 MUi3NkBp M3LtWmlEPTBiPTCwMlE3ODdizszN NIDZb2Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES2OVg1Pid-MUi0OlU5PDZ:L3G+
NCI/ADR M3HnS2N6fG:2b4jpZ4l1gSCjc4PhfS=> M3rye|czKGh? MnLkTWM2OCB;IECuN{DPxE1? NG\OdnA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOES2OVg1Pid-MUi0OlU5PDZ:L3G+
1A9PTX10 MoHaR5l1d3SxeHnjbZR6KGG|c3H5 MVG3NkBp NX\NbHJVUUN3MDC9JFAvPTN{OUWg{txO MoHoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NkW4OFYoRjF6NE[1PFQ3RC:jPh?=
HT29 MlTFRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MkX1S2k2OCB;IECuNFE2KM7:TR?= M33uXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NUCyOlM6Lz5zOEWwNlY{QTxxYU6=
M21 MmjKRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M17w[mdKPTBiPTCwMlA{PyEQvF2= MoPWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3MEK2N|koRjF6NUCyOlM6RC:jPh?=
MCF7 MXnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NYfaNpF5T0l3MDC9JFAvODV2IN88US=> NV32OnBlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1NFI3OzlpPkG4OVAzPjN7PD;hQi=>
HepG2 MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXjUd2p6PzJiaB?= NELCTItKSzVyIE2gNE4xODV7IN88US=> MmXsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3MUK5PFQoRjF6NUGyPVg1RC:jPh?=
HepG2/Dox MmLWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHmyWFY4OiCq MnjzTWM2OCB;IEGuOEDPxE1? NWTTTIM3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1NVI6QDRpPkG4OVEzQTh2PD;hQi=>
HT29 NHLLbZRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Moi2OFghcA>? MlTJS2k2OCB;IECuNFE2KM7:TR?= NH3WUow9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEW3PVM5Pyd-MUi1O|k{QDd:L3G+
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MCF7 NFLOcnRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M362NFQ5KGh? MojFS2k2OCB;IECuNFU1KM7:TR?= MmrMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3N{mzPFcoRjF6NUe5N|g4RC:jPh?=
KB403 NH7FS|hEgXSxdH;4bYNqfHliYYPzZZk> M3znZlI1KGh? MljCTWM2OCB;IECuNFAyKM7:TR?= MlW0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3OE[0PVEoRjF6NUi2OFkyRC:jPh?=
WRL68 MmPtR5l1d3SxeHnjbZR6KGG|c3H5 MlWxNlQhcA>? MVjJR|UxKD1iMD6wNFQh|ryP NH7wd289[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEW4OlQ6OSd-MUi1PFY1QTF:L3G+
MCF7 MlrBR5l1d3SxeHnjbZR6KGG|c3H5 M1j3dlI1KGh? M3z6emlEPTBiPTCwMlAxPiEQvF2= M3n5O|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NUi2OFkyLz5zOEW4OlQ6OTxxYU6=
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HEPG2 M4LRV2N6fG:2b4jpZ4l1gSCjc4PhfS=> NWHwNpZzOjRiaB?= MWLJR|UxKD1iMD6wNFkh|ryP M{DCd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NUi2OFkyLz5zOEW4OlQ6OTxxYU6=
HCT116 MXXDfZRwfG:6aXPpeJkh[XO|YYm= MWXJR|UxKD1iMD6wNVM3KM7:TR?= MnHVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4ME[1OFAoRjF6NkC2OVQxRC:jPh?=
SF268 Mn7kR5l1d3SxeHnjbZR6KGG|c3H5 NF;n[nhKSzVyIE2gNE4xOTV|IN88US=> MlTEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh4ME[1OFAoRjF6NkC2OVQxRC:jPh?=
A549 NXrYeFhLS3m2b4TvfIlkcXS7IHHzd4F6 MWLJR|UxKD1iMD6wNlMyKM7:TR?= NXf5[YZ4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi2NFY2PDBpPkG4OlA3PTRyPD;hQi=>
MDA-MB-231 Ml7PR5l1d3SxeHnjbZR6KGG|c3H5 NXPTU3ZCUUN3MDC9JFAvODRyNTFOwG0> NGHZZ4g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOE[wOlU1OCd-MUi2NFY2PDB:L3G+
SF295 NUPxPZo4S3m2b4TvfIlkcXS7IHHzd4F6 NXHDWXRsUUN3MDC9JFAvOjlizszN MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZyNkW0NEc,OTh4ME[1OFA9N2F-
MDA-MB-435 NE\QRnpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NHL3dZI4OiCq MUXHTVUxKD1iMD6wNFQh|ryP MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZzMEm5OUc,OTh4MUC5PVU9N2F-
HT29 MnztRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M2DZUlQ5KGh? MkTXS2k2OCB;IECuNFE2KM7:TR?= NYTsepNJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi2NVc1OTRpPkG4OlE4PDF2PD;hQi=>
M21 NWfvRmlmSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M4\nRVQ5KGh? NIXWVGdIUTVyIE2gNE4xOzdizszN MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZzN{SxOEc,OTh4MUe0NVQ9N2F-
MCF7 NUjBXGtxSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M{jhOVQ5KGh? NEPiVo1IUTVyIE2gNE4xPTRizszN MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZzN{SxOEc,OTh4MUe0NVQ9N2F-
SKOV3 M4PwO2N6fG:2b4jpZ4l1gSCjc4PhfS=> Mn63TWM2OCB;IEKuOFMh|ryP NX3RUItwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3NFEzQDFpPkG4O|AyOjhzPD;hQi=>
KB MlznR5l1d3SxeHnjbZR6KGG|c3H5 NV3GTXZkUUN3MDC9JFIvPTRizszN NFnMV5Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEewNVI5OSd-MUi3NFEzQDF:L3G+
Eca109 MVPDfZRwfG:6aXPpeJkh[XO|YYm= Mki4TWM2OCB;IEKuO|Mh|ryP NYjsUlFRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3NFEzQDFpPkG4O|AyOjhzPD;hQi=>
PC3 M3;uUWN6fG:2b4jpZ4l1gSCjc4PhfS=> NGD4NWZKSzVyIE2gNk45PSEQvF2= Ml;pQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5MEGyPFEoRjF6N{CxNlgyRC:jPh?=
SMMC7721 NFX2[mdEgXSxdH;4bYNqfHliYYPzZZk> NIrTeFBKSzVyIE2gNk45PiEQvF2= M3TBR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{CxNlgyLz5zOEewNVI5OTxxYU6=
MCF7 NEPsPG1EgXSxdH;4bYNqfHliYYPzZZk> M2PaTmlEPTBiPTCyMlk5KM7:TR?= NWDrPZl{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3NFEzQDFpPkG4O|AyOjhzPD;hQi=>
HeLa MknCR5l1d3SxeHnjbZR6KGG|c3H5 NVPZNVVHUUN3MDC9JFMvOTFizszN Mm\sQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5MEGyPFEoRjF6N{CxNlgyRC:jPh?=
HCT8 NGPxfo5EgXSxdH;4bYNqfHliYYPzZZk> NVzaR3F7UUN3MDC9JFMvOjlizszN MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDdyMUK4NUc,OTh5MEGyPFE9N2F-
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HepG2 MlfNRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MYm0PEBp MkHiTWM2OCB;IECuOlIh|ryP Mn:1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5MEGzNFEoRjF6N{CxN|AyRC:jPh?=
PC3 M3;FUGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M4P2cFQ5KGh? M4LkbGlEPTBiPTCyMlc{KM7:TR?= M3\ublxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{CxN|AyLz5zOEewNVMxOTxxYU6=
HCT116 MYDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MXG0PEBp NYjaUIV4UUN3MDC9JFYvOThizszN NFn5NGI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEewNVMxOSd-MUi3NFE{ODF:L3G+
A549 NXyzRYx2S3m2b4TvfIlkcXS7IHHzd4F6 NF\jb|NKSzVyIE2gNE4xODJizszN M2jLV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{G1O|gzLz5zOEexOVc5OjxxYU6=
CCRF-CEM NWLUO5oyS3m2b4TvfIlkcXS7IHHzd4F6 NIjDSFE4OiCq NE\IeYFKSzVyIE2gNE4xODFzIN88US=> MkCxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5NUK4OlkoRjF6N{WyPFY6RC:jPh?=
SKOV3 NYjkfZp5SW62aXPhcoNmeiCjc4PhfS=> NUPMNopnPzJiaB?= MkX3TWM2OCB;IECuNFAyOzRizszN M2L3cVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{[yN|U5Lz5zOEe2NlM2QDxxYU6=
MCF7 MlnMR5l1d3SxeHnjbZR6KGG|c3H5 MkjqSWQ2OCB;IECuNFA{OiEQvF2= NYS1S5JIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5NlY4ODFpPkG4PVI3PzBzPD;hQi=>
NCI/ADR-RES NHHGNnBEgXSxdH;4bYNqfHliYYPzZZk> M3fBR2VFPTBiPTCxMlUh|ryP MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDl{NkewNUc,OTh7Mk[3NFE9N2F-
PANC1 NIfRTGFEgXSxdH;4bYNqfHliYYPzZZk> MnH3O|IhcA>? MUPJR|UxKD1iMD6wNFk6KM7:TR?= M33LclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUWxO|g4Lz5zOEm1NVc5PzxxYU6=
DLD1 NWnOXppvS3m2b4TvfIlkcXS7IHHzd4F6 NH3nSHg4OiCq NVLzcZQ1UUN3MDC9JFAvODJ{IN88US=> MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDl3MUe4O{c,OTh7NUG3PFc9N2F-
AsPC1 MVLDfZRwfG:6aXPpeJkh[XO|YYm= NWD0eYQ2PzJiaB?= NXH0R49VUUN3MDC9JFAvODh7IN88US=> NVrFWmRURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5OVE4QDdpPkG4PVUyPzh5PD;hQi=>
NCI/ADR-RES MW\DfZRwfG:6aXPpeJkh[XO|YYm= NIrFeWU4OiCq NVLVSWs{UUN3MDC9JFEvOyEQvF2= NWL6Ro9JRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5OVE4QDdpPkG4PVUyPzh5PD;hQi=>
MCF7 NWLUT3dKS3m2b4TvfIlkcXS7IHHzd4F6 MX3FSFUxKD1iMD6wNFIyKM7:TR?= M{nJdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUe3OlU6Lz5zOEm3O|Y2QTxxYU6=
NCI/ADR-RES M1\5bWN6fG:2b4jpZ4l1gSCjc4PhfS=> M2rOPGVFPTBiPTCyJO69VQ>? MlrlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7N{e2OVkoRjF6OUe3OlU6RC:jPh?=
A431 MXjDfZRwfG:6aXPpeJkh[XO|YYm= MUe3NkBp NXruSnhkUUN3MDC9JFAvODJ3MTFOwG0> M3vMdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUmwOVc1Lz5zOEm5NFU4PDxxYU6=
MCF7 NI\iUHpEgXSxdH;4bYNqfHliYYPzZZk> MUm3NkBp NEnEfnpKSzVyIE2gNE4xOzlizszN NH72cmc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEm5NFU4PCd-MUi5PVA2PzR:L3G+
MDA-MB-231 MXnDfZRwfG:6aXPpeJkh[XO|YYm= M{H2RVczKGh? MVLJR|UxKD1iMD6wOFcyKM7:TR?= MlLUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7OUC1O|QoRjF6OUmwOVc1RC:jPh?=
SKOV3 NXPiRZVpS3m2b4TvfIlkcXS7IHHzd4F6 NYjVbFBJPzJiaB?= M3LXZWlEPTBiPTCwMlA3PThizszN MnzhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7OUC1O|QoRjF6OUmwOVc1RC:jPh?=
PANC1 MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1G4c|czKGh? MVzJR|UxKD1iMD6wNFk6KM7:TR?= MlTjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyMkK2O|koRjF7MEKyOlc6RC:jPh?=
DLD1 MnLyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NI\xNJM4OiCq MoXPTWM2OCB;IECuNFIzKM7:TR?= NGDZUoY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUCyNlY4QSd-MUmwNlI3Pzl:L3G+
AsPC1 NIGxVlVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIHqRnc4OiCq MkSzTWM2OCB;IECuNFg6KM7:TR?= NYCxPJhkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNlI3PzlpPkG5NFIzPjd7PD;hQi=>
NCI/ADR MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mn36O|IhcA>? MXnJR|UxKD1iMT6zJO69VQ>? Ml[1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyMkK2O|koRjF7MEKyOlc6RC:jPh?=
A2780 MVzBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MVWyJIRigXN? M1PUd2lEPTBiPTCwMlAzOzRizszN M1vmOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEK4NVAzLz5zOUCyPFExOjxxYU6=
KB M{K4R2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NUDwZZlKOyCmYYnz NVfEXGFuUUN3MDC9JFAvODB{NTFOwG0> NI\JfXA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC0NVI1Pyd-MUmwOFEzPDd:L3G+
COLO205 MWrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MVuyOEBp NGjidXRKSzVyIE2gNE4xODN|IN88US=> MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB2MUK0O{c,OTlyNEGyOFc9N2F-
KB 8.5 MknMRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NXO5VoJkOyCmYYnz NVPZdnY1UUN3MDC9JFAvODJ4IN88US=> NVPJ[XRMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOFEzPDdpPkG5NFQyOjR5PD;hQi=>
KBV1 MVvBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M2fMZlMh\GG7cx?= MYrJR|UxKD1iMj6wNVMh|ryP NIe5Rpc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC0NVI1Pyd-MUmwOFEzPDd:L3G+
KB NWe3PXk6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGPXSmk4OiCq MX7JR|UxKD1iMD6wNFM{KM7:TR?= NV23UVNrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4PzNpPkG5NFU{Pzd|PD;hQi=>
KB-7D NGOwXpRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVjvT45UPzJiaB?= NVT2dZd4UUN3MDC9JFAvODB5OTFOwG0> MmnWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3O|MoRjF7MEWzO|c{RC:jPh?=
Pgp170 overexpressing multidrug resistant-KB-TAX50 NYn3d2MxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV22N2NpPzJiaB?= NHHwbmhKSzVyIE2gNE4zPzNizszN MnTEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3O|MoRjF7MEWzO|c{RC:jPh?=
NPC-TW01 MoPKR5l1d3SxeHnjbZR6KGG|c3H5 MVe3NkBp NFXrdGlKSzVyIE2gNE4xODZizszN NXrxT|VsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4QDFpPkG5NFU{PzhzPD;hQi=>
MES-SA NUi2bVBFS3m2b4TvfIlkcXS7IHHzd4F6 NGHyZ2I4OiCq NEHuWVFKSzVyIE2gNE4xODhizszN M4[yZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|gyLz5zOUC1N|c5OTxxYU6=
NCI-H838 NVu4WFBES3m2b4TvfIlkcXS7IHHzd4F6 MoCxO|IhcA>? Mm\ITWM2OCB;IECuNFI3KM7:TR?= NF35NI89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC1N|c5OSd-MUmwOVM4QDF:L3G+
HCT116 MX\DfZRwfG:6aXPpeJkh[XO|YYm= MYG3NkBp M4LpeGlEPTBiPTCwMlA3OSEQvF2= Moj5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3PFEoRjF7MEWzO|gyRC:jPh?=
cells after 72 hrs by MTT assay MYLDfZRwfG:6aXPpeJkh[XO|YYm= MnvTTWM2OCB;IEWuNVQh|ryP MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3M{e4NUc,OTlyNUO3PFE9N2F-
Hep3B NX7ZWYxIS3m2b4TvfIlkcXS7IHHzd4F6 M3nzc|czKGh? NFTnboxKSzVyIE2gO{4zPiEQvF2= NHzGSo49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC1N|c5OSd-MUmwOVM4QDF:L3G+
A498 MkC5R5l1d3SxeHnjbZR6KGG|c3H5 NU\mdnoyPzJiaB?= M4[2WWlEPTBiPTC4MlgyKM7:TR?= MkfSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3PFEoRjF7MEWzO|gyRC:jPh?=
NB4 NWnpXFhwS3m2b4TvfIlkcXS7IHHzd4F6 MomyOFghcA>? NGjLclJKSzVyIE2gNE4yKM7:TR?= MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB5MkKwPUc,OTlyN{KyNFk9N2F-
A549 NGHDXmdEgXSxdH;4bYNqfHliYYPzZZk> MUe0PEBp MWLJR|UxKD1iMD6xJO69VQ>? MkLXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyN{KyNFkoRjF7MEeyNlA6RC:jPh?=
MCF7 NIjyV2VEgXSxdH;4bYNqfHliYYPzZZk> MmTyOFghcA>? NFzzTWNKSzVyIE2gNE4yKM7:TR?= NVzVWJhERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwO|IzODlpPkG5NFczOjB7PD;hQi=>
SH-SY5Y MmTRR5l1d3SxeHnjbZR6KGG|c3H5 MXu0PEBp M4C2[GlEPTBiPTCwMlIh|ryP NFvzUGg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC3NlIxQSd-MUmwO|IzODl:L3G+
PC3 M162UWN6fG:2b4jpZ4l1gSCjc4PhfS=> M2rRW|Q5KGh? MYLJR|UxKD1iMD6yJO69VQ>? M13MXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEeyNlA6Lz5zOUC3NlIxQTxxYU6=
DLD1 Ml64R5l1d3SxeHnjbZR6KGG|c3H5 M2rzbFczKGh? MWrHTVUxKD1iMD6wNUDPxE1? NEnWU5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC4NVI1QSd-MUmwPFEzPDl:L3G+
B16 MojxR5l1d3SxeHnjbZR6KGG|c3H5 NY\i[2dXPzJiaB?= NX7VPHIzT0l3MDC9JFAvODFizszN NXT0WYhIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwPFEzPDlpPkG5NFgyOjR7PD;hQi=>
A172 MmLHR5l1d3SxeHnjbZR6KGG|c3H5 M1e1W|czKGh? MUHHTVUxKD1iMD6wNUDPxE1? NIXJeWM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC4NVI1QSd-MUmwPFEzPDl:L3G+
HeLa NVWwZYR3S3m2b4TvfIlkcXS7IHHzd4F6 MmroO|IhcA>? NUm4ZnR7T0l3MDC9JFAvODJizszN M4jT[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEixNlQ6Lz5zOUC4NVI1QTxxYU6=
U87 MUTDfZRwfG:6aXPpeJkh[XO|YYm= MYq3NkBp NXrve4VKT0l3MDC9JFAvODJizszN M17yVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEixNlQ6Lz5zOUC4NVI1QTxxYU6=
SiHa NG\kUG9EgXSxdH;4bYNqfHliYYPzZZk> Mkm4O|IhcA>? MmjwS2k2OCB;IECuNFMh|ryP NV[0V5FbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwPFEzPDlpPkG5NFgyOjR7PD;hQi=>
HeLa NFSydXZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NIq1cpo6PiCq MknUTWM2OCB;IECuNFAyKM7:TR?= MlzhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyOUG1O|koRjF7MEmxOVc6RC:jPh?=
SKOV3 Mom4RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NWLLbIVtQTZiaB?= MlOwTWM2OCB;IECuNFE3KM7:TR?= NX3K[FMxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwPVE2PzlpPkG5NFkyPTd7PD;hQi=>
BGC823 MknERY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M1;BUVk3KGh? M4qzbmlEPTBiPTCwMlAyQDlizszN MnvRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyOUG1O|koRjF7MEmxOVc6RC:jPh?=
HCT116 MUTDfZRwfG:6aXPpeJkh[XO|YYm= M3G1SlczKGh? NFPD[3RKSzVyIE2gNE4xODFzIN88US=> NV;GZmNoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmxNlQzPTBpPkG5NVI1OjVyPD;hQi=>
CCRF-CEM NGTZVWtEgXSxdH;4bYNqfHliYYPzZZk> NVjxS4trPzJiaB?= NF60fo1KSzVyIE2gNE4xODNzIN88US=> NV\x[pFiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmxNlQzPTBpPkG5NVI1OjVyPD;hQi=>
MX1 MUHDfZRwfG:6aXPpeJkh[XO|YYm= MV23NkBp MXvJR|UxKD1iMD6wOFYh|ryP MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF{NEK1NEc,OTlzMkSyOVA9N2F-</