Antiviral

阻害剤の選択性比較

カタログ番号 製品カタログ 溶解度(25°C)
DMSO アルコール
S1102 U0126-EtOH <1 mg/mL 85 mg/mL <1 mg/mL
S1537 Vadimezan (ASA404) <1 mg/mL 7 mg/mL ''''<1 mg/mL
S2713 Geldanamycin (NSC 122750) <1 mg/mL 36 mg/mL '<1 mg/mL
S1401 Tenofovir 2 mg/mL 4 mg/mL <1 mg/mL
S9926 ML-SA1 <1 mg/mL 18 mg/mL '2 mg/mL
E0010 Hypocrellin A <1 mg/mL 25 mg/mL ''<1 mg/mL
S4879 Tenofovir hydrate 10 mg/mL <1 mg/mL ''<1 mg/mL
S3356 Phosphonoacetic acid 28 mg/mL 28 mg/mL '''28 mg/mL
S3380 Tecovirimat <1 mg/mL 75 mg/mL ''''''75 mg/mL
S1623 Acetylcysteine (N-acetylcysteine) 33 mg/mL 33 mg/mL '33 mg/mL
S2239 Tubacin <1 mg/mL 100 mg/mL <1 mg/mL
S8750 NGI-1 (ML414) <1 mg/mL 79 mg/mL '<1 mg/mL
S6867 Glyceryl monocaprate (Monocaprin) <1 mg/mL 49 mg/mL ''49 mg/mL
S9303 Saikosaponin B2 -1 mg/mL 100 mg/mL -1 mg/mL
S2764 DTNB <1 mg/mL 79 mg/mL '79 mg/mL
S7775 Emricasan (IDN-6556) <1 mg/mL 100 mg/mL '''100 mg/mL
S9063 Harringtonine -1 mg/mL 100 mg/mL -1 mg/mL
S8932 Remdesivir (GS-5734) <1 mg/mL 100 mg/mL ''''16 mg/mL
S9669 U18666A 40 mg/mL 30 mg/mL '''''85 mg/mL
S6801 AKOS B018304 <1 mg/mL 53 mg/mL '2 mg/mL
S6814 GS-441524 <1 mg/mL 58 mg/mL '<1 mg/mL
S3251 Goitrin -1 mg/mL 100 mg/mL -1 mg/mL
S2504 Ribavirin (ICN-1229) 49 mg/mL 49 mg/mL ''<1 mg/mL
S1807 Aciclovir (BW 248U) <1 mg/mL 45 mg/mL ''<1 mg/mL
S1637 Docosanol <1 mg/mL <1 mg/mL '4 mg/mL
S2420 Aloperine 12 mg/mL 2 mg/mL '46 mg/mL
S2486 Moroxydine HCl 42 mg/mL 42 mg/mL '<1 mg/mL
S2467 Famciclovir 64 mg/mL 64 mg/mL '48 mg/mL
S1883 Idoxuridine <1 mg/mL 35 mg/mL '<1 mg/mL
S4184 Penciclovir 1 mg/mL 34 mg/mL ''<1 mg/mL
S8071 UNC0638 6 mg/mL 100 mg/mL 100 mg/mL
S9224 Dehydroandrographolide Succinate -1 mg/mL 100 mg/mL -1 mg/mL
S5684 Lapachol -1 mg/mL 48 mg/mL -1 mg/mL
S9278 Saikosaponin C -1 mg/mL 100 mg/mL -1 mg/mL
S4942 4-Hydroxy-3,5-dimethoxybenzyl alcohol -1 mg/mL 36 mg/mL ''-1 mg/mL
S5020 Tilorone dihydrochloride 96 mg/mL 43 mg/mL '96 mg/mL
S5016 Isoprinosine 100 mg/mL 100 mg/mL '2 mg/mL
S9078 Epigoitrin -1 mg/mL 4.89 mg/mL -1 mg/mL
S6067 2,4-dichlorobenzyl alcohol -1 mg/mL 35 mg/mL '-1 mg/mL
S2334 Oleanolic Acid <1 mg/mL 21 mg/mL 7 mg/mL
S9099 Orientin -1 mg/mL 89 mg/mL -1 mg/mL
S9328 5,6,7-Trimethoxyflavone -1 mg/mL 10 mg/mL '-1 mg/mL
S9120 Scutellarein -1 mg/mL 57 mg/mL -1 mg/mL
S4518 Chloroxylenol <1 mg/mL 31 mg/mL '31 mg/mL
S9136 Neochlorogenic acid -1 mg/mL 70 mg/mL -1 mg/mL
S4408 Procodazole <1 mg/mL 38 mg/mL '''<1 mg/mL

Antiviral製品

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1102

U0126-EtOH

U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. U0126 inhibits autophagy and mitophagy with antiviral activity.

S1537

Vadimezan (ASA404)

Vadimezan (ASA404, NSC 640488, DMXAA) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. DMXAA (Vadimezan) is also a STING agonist with potential antineoplastic activity. DMXAA (Vadimezan) potently induces IFN-β but relatively low TNF-α expression in vitro. DMXAA (Vadimezan) has antiviral activity. Phase 3.

S2713

Geldanamycin (NSC 122750)

Geldanamycin (NSC 122750) is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association. Geldanamycin attenuates virus infection-induced ALI (acute lung injury)/ARDS (acute respiratory distress syndrome) by reducing the host's inflammatory responses.

S1401

Tenofovir

Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections.

S9926

ML-SA1

ML-SA1 (Mucolipin synthetic agonist 1) is an activator of TRPML channels. ML-SA1 also inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 values of ML-SA1 against DENV2 RNA and ZIKV RNA are 8.93 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral.

E0010

Hypocrellin A

Hypocrellin A (HA) is a perylenequinone isolated from Shiraia bambusicola that shows antiviral, antimicrobial and anticancer activity through mediating multiple signaling pathways. Hypocrellin A also is a selective and potent inhibitor of PKC.

S4879

Tenofovir hydrate

Tenofovir (GS-1278) hydrate blocks reverse transcriptase and hepatitis B virus infections.

S3356

Phosphonoacetic acid

Phosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.

S3380

Tecovirimat

Tecovirimat (Arestvyr, SIGA-246, ST-246, TPOXX) is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat is developed for the treatment of smallpox infection.

S1623

Acetylcysteine (N-acetylcysteine)

Acetylcysteine (N-acetyl-l-cysteine, NAC) is a ROS(reactive oxygen species) inhibitor that antagonizes the activity of proteasome inhibitors. It is also a tumor necrosis factor production inhibitor. Acetylcysteine(N-acetyl-l-cysteine) suppresses TNF-induced NF-κB activation through inhibition of IκB kinases. Acetylcysteine(N-acetyl-l-cysteine) induces apoptosis via the mitochondria-dependent pathway. Acetylcysteine(N-acetyl-l-cysteine) inhibits ferroptosis and virus replication.Solutions of Acetylcysteine are best fresh-prepared.

S2239

Tubacin

Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM in a cell-free assay, approximately 350-fold selectivity over HDAC1. Tubacin reduces the replication of the Japanese Encephalitis Virus via the decrease of viral RNA synthesis.

S8750

NGI-1 (ML414)

NGI-1 (ML414) is an aminobenzamide-sulfonamide compound that targets both oligosaccharyltransferase (OST) isoforms and therefore may exhibit antiviral activity against flaviviruses.

S5554

Lanatoside C

Lanatoside C is a cardiac glycoside with antiviral and anti-tumor activity. Lanatoside C induces G2/M cell cycle arrest and induces autophagy and apoptosis via attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR signaling pathways.

S6867

Glyceryl monocaprate (Monocaprin)

Monocaprin (Glyceryl caprate) is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.

S9303

Saikosaponin B2

Saikosaponin B2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.

S2764

DTNB

DTNB (Ellman’s Reag, Ellmans Reagenz, 5,5′-Dithiobis(2-nitrobenzoic acid), 5,5′-Dithiobis-2-nitrobenzoesäure) is a non-fluorescent probe used to quantify the number or concentration of thiol groups in a sample. DTNB is also an allosteric inhibitor of dengue virus protease (NS2B-NS3pro) and Streptomyces proteases.

S7775

Emricasan (IDN-6556)

Emricasan (IDN-6556, PF 03491390, PF-03491390) is a potent irreversible pan-caspase inhibitor. Emricasan is an inhibitor of Zika virus infection.

S9063

Harringtonine

Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.

S8932

Remdesivir (GS-5734)

Remdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.

S9669

U18666A

U18666A (U18) is an inhibitor of intra-cellular cholesterol transport that inhibits dengue virus entry and replication.

S6801

AKOS B018304

AKOS B018304, an arylalkylidene derivative with polar substitution at para-position, is a potent inhibitor of chikungunya virus with low micro molar activity.

S6814

GS-441524

GS-441524, a molecular precursor to a pharmacologically active nucleoside triphosphate molecule, is a potent inhibitor of feline infectious peritonitis virus (FIPV) with EC50 of 0.78 μM.

S3251

Goitrin

Goitrin (DL-Goitrin, (R, S)-Goitrin, R,S-goitrin) is one of the main constituent of Radix isatidis (Banlangen) which is widely used as a traditional Chinese medicine for treating fever and removing toxic heat. Goitrin exhibits antiviral and antiendotoxin activity.

S2504

Ribavirin (ICN-1229)

Ribavirin (NSC-163039, ICN-1229, RTCA, Tribavirin), a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.

S1807

Aciclovir (BW 248U)

Acyclovir (BW 248U, Acyclovir, Acycloguanosine, Zovirax, ACV, NSC 645011) is a synthetic nucleoside analogue active against herpesviruses. Acyclovir induces cell cycle perturbation and apoptosis in Jurkat leukemia cells.

S1637

Docosanol

Docosanol is a saturated fatty alcoholused traditionally as an emollient, emulsifier, and thickener in cosmetics, nutritional supplement. (ED50=2.5 mg/mL for plaque inhibition, and ED50=1.7 mg/mL for inhibition of virus production)

S2420

Aloperine

Aloperine is an isolated alkaloid in sophora plants such as Sophora alopecuroides L, and exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.

S2486

Moroxydine HCl

Moroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.

S2467

Famciclovir

Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.

S1883

Idoxuridine

Idoxuridine (NSC 39661, SKF 14287) is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.

S4184

Penciclovir

Penciclovir (BRL-39123, VSA 671) is a purine acyclic nucleoside analogue with potent antiviral activity.

S8071

UNC0638

UNC0638 is a potent, selective and cell-penetrant chemical probe for G9a and GLP histone methyltransferase with IC50 of <15 nM and 19 nM, respectively, shows selectivity over a wide range of epigenetic and non-epigenetic targets. UNC0638 has anti-viral activities.

S9224

Dehydroandrographolide Succinate

Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.

S5684

Lapachol

Lapachol (Tecomin, CI75490, Bethabarra wood, Greenhartin), a natural compound isolated from the bark of the lapacho tree, shows both antimicrobial and antiviral activity.

S9278

Saikosaponin C

Saikosaponin C is a triterpene saponin found in Bupleurum that exhibits antiviral and pro-angiogenic activities.

S4942

4-Hydroxy-3,5-dimethoxybenzyl alcohol

4-Hydroxy-3,5-dimethoxybenzyl alcohol (Syringic alcohol, Syringyl alcohol) is a kind of phenol with antiviral properties.

S5020

Tilorone dihydrochloride

Tilorone dihydrochloride is a broad-spectrum, orally active antiviral agent that activates interferon production. It has antitumor, anti-inflammatory properties.

S5016

Isoprinosine

Isoprinosine (Inosine pranobex, Immunovir, Groprinosin, Delimmun) is an immunopharmacologic agent with antiviral activities.

S9078

Epigoitrin

Epigoitrin (Goitrin, BA-51-090278), the main bioactive constituent of Radix isatidis, exerts antiviral, anticancer, and antithyroid activities.

S6067

2,4-dichlorobenzyl alcohol

2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections.

S2334

Oleanolic Acid

Oleanolic Acid (Caryophyllin) is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana, which exerts antitumor and antiviral properties.

S9099

Orientin

Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.

S9328

5,6,7-Trimethoxyflavone

5,6,7-Trimethoxyflavone (Baicalein Trimethyl Ether), methylations of the hydroxyl groups of oroxylin A or baicalein, has various pharmacological activities including antiviral, anticancer and antibacterial.

S9120

Scutellarein

Scutellarein (6-Hydroxyapigenin), extracted from the perennial herb Scutellaria lateriflora, has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities

S4518

Chloroxylenol

Chloroxylenol is a broad-spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.

S9136

Neochlorogenic acid

Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.

S4408

Procodazole

Procodazole (Propazol, 2-Benzimidazolepropionic acid, 3-(1H-benzimidazole-2) propanoic acid) is used as a potentiator which is non-specific active immunoprotective against viral and bacterial infections.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S1102

U0126-EtOH

U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. U0126 inhibits autophagy and mitophagy with antiviral activity.

S1537

Vadimezan (ASA404)

Vadimezan (ASA404, NSC 640488, DMXAA) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. DMXAA (Vadimezan) is also a STING agonist with potential antineoplastic activity. DMXAA (Vadimezan) potently induces IFN-β but relatively low TNF-α expression in vitro. DMXAA (Vadimezan) has antiviral activity. Phase 3.

S2713

Geldanamycin (NSC 122750)

Geldanamycin (NSC 122750) is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association. Geldanamycin attenuates virus infection-induced ALI (acute lung injury)/ARDS (acute respiratory distress syndrome) by reducing the host's inflammatory responses.

S1401

Tenofovir

Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections.

S9926

ML-SA1

ML-SA1 (Mucolipin synthetic agonist 1) is an activator of TRPML channels. ML-SA1 also inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 values of ML-SA1 against DENV2 RNA and ZIKV RNA are 8.93 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral.

E0010

Hypocrellin A

Hypocrellin A (HA) is a perylenequinone isolated from Shiraia bambusicola that shows antiviral, antimicrobial and anticancer activity through mediating multiple signaling pathways. Hypocrellin A also is a selective and potent inhibitor of PKC.

S4879

Tenofovir hydrate

Tenofovir (GS-1278) hydrate blocks reverse transcriptase and hepatitis B virus infections.

S3356

Phosphonoacetic acid

Phosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.

S3380

Tecovirimat

Tecovirimat (Arestvyr, SIGA-246, ST-246, TPOXX) is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat is developed for the treatment of smallpox infection.

S1623

Acetylcysteine (N-acetylcysteine)

Acetylcysteine (N-acetyl-l-cysteine, NAC) is a ROS(reactive oxygen species) inhibitor that antagonizes the activity of proteasome inhibitors. It is also a tumor necrosis factor production inhibitor. Acetylcysteine(N-acetyl-l-cysteine) suppresses TNF-induced NF-κB activation through inhibition of IκB kinases. Acetylcysteine(N-acetyl-l-cysteine) induces apoptosis via the mitochondria-dependent pathway. Acetylcysteine(N-acetyl-l-cysteine) inhibits ferroptosis and virus replication.Solutions of Acetylcysteine are best fresh-prepared.

S2239

Tubacin

Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM in a cell-free assay, approximately 350-fold selectivity over HDAC1. Tubacin reduces the replication of the Japanese Encephalitis Virus via the decrease of viral RNA synthesis.

S8750

NGI-1 (ML414)

NGI-1 (ML414) is an aminobenzamide-sulfonamide compound that targets both oligosaccharyltransferase (OST) isoforms and therefore may exhibit antiviral activity against flaviviruses.

S5554

Lanatoside C

Lanatoside C is a cardiac glycoside with antiviral and anti-tumor activity. Lanatoside C induces G2/M cell cycle arrest and induces autophagy and apoptosis via attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR signaling pathways.

S6867

Glyceryl monocaprate (Monocaprin)

Monocaprin (Glyceryl caprate) is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.

S9303

Saikosaponin B2

Saikosaponin B2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.

S2764

DTNB

DTNB (Ellman’s Reag, Ellmans Reagenz, 5,5′-Dithiobis(2-nitrobenzoic acid), 5,5′-Dithiobis-2-nitrobenzoesäure) is a non-fluorescent probe used to quantify the number or concentration of thiol groups in a sample. DTNB is also an allosteric inhibitor of dengue virus protease (NS2B-NS3pro) and Streptomyces proteases.

S7775

Emricasan (IDN-6556)

Emricasan (IDN-6556, PF 03491390, PF-03491390) is a potent irreversible pan-caspase inhibitor. Emricasan is an inhibitor of Zika virus infection.

S9063

Harringtonine

Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.

S8932

Remdesivir (GS-5734)

Remdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.

S9669

U18666A

U18666A (U18) is an inhibitor of intra-cellular cholesterol transport that inhibits dengue virus entry and replication.

S6801

AKOS B018304

AKOS B018304, an arylalkylidene derivative with polar substitution at para-position, is a potent inhibitor of chikungunya virus with low micro molar activity.

S6814

GS-441524

GS-441524, a molecular precursor to a pharmacologically active nucleoside triphosphate molecule, is a potent inhibitor of feline infectious peritonitis virus (FIPV) with EC50 of 0.78 μM.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S3251

Goitrin

Goitrin (DL-Goitrin, (R, S)-Goitrin, R,S-goitrin) is one of the main constituent of Radix isatidis (Banlangen) which is widely used as a traditional Chinese medicine for treating fever and removing toxic heat. Goitrin exhibits antiviral and antiendotoxin activity.

製品コード 製品説明 文献中Selleckの製品使用例 お客様のフィードバック
S2504

Ribavirin (ICN-1229)

Ribavirin (NSC-163039, ICN-1229, RTCA, Tribavirin), a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.

2021, S0166-3542(21)00068-1

2021, 22(9)4559

2020, acsinfecdis.0c00486

S1807

Aciclovir (BW 248U)

Acyclovir (BW 248U, Acyclovir, Acycloguanosine, Zovirax, ACV, NSC 645011) is a synthetic nucleoside analogue active against herpesviruses. Acyclovir induces cell cycle perturbation and apoptosis in Jurkat leukemia cells.

2020, 6(49)eabd9443

2020, 6(11):2926-2937

2020, AAC.00245-20

S1637

Docosanol

Docosanol is a saturated fatty alcoholused traditionally as an emollient, emulsifier, and thickener in cosmetics, nutritional supplement. (ED50=2.5 mg/mL for plaque inhibition, and ED50=1.7 mg/mL for inhibition of virus production)

S2420

Aloperine

Aloperine is an isolated alkaloid in sophora plants such as Sophora alopecuroides L, and exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.

2020, 10.1007/s00432-020-03157-2

2019, 20(21)E5315

2019, 7:e7652

S2486

Moroxydine HCl

Moroxydine HCl is a synthetic antiviral compound chemically belonging to the series of the heterocyclic biguanidines.

2021, 10.1007/s13577-021-00579-z

2020, 19;20:58

2020, 10.1007/s13577-020-00425-8

S2467

Famciclovir

Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.

2021, 10.1007/s13577-021-00579-z

2020, 6(49)eabd9443

2020, 19;20:58

S1883

Idoxuridine

Idoxuridine (NSC 39661, SKF 14287) is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.

S4184

Penciclovir

Penciclovir (BRL-39123, VSA 671) is a purine acyclic nucleoside analogue with potent antiviral activity.

2021, 10.1021/acsinfecdis.1c00083

2021, S0166-3542(21)00068-1

2020, 6(49)eabd9443

S8071

UNC0638

UNC0638 is a potent, selective and cell-penetrant chemical probe for G9a and GLP histone methyltransferase with IC50 of <15 nM and 19 nM, respectively, shows selectivity over a wide range of epigenetic and non-epigenetic targets. UNC0638 has anti-viral activities.

2021, 7(3)eaba8053

2021, 2021:6650781

2021, 16(6):e0252504

S9224

Dehydroandrographolide Succinate

Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.

S5684

Lapachol

Lapachol (Tecomin, CI75490, Bethabarra wood, Greenhartin), a natural compound isolated from the bark of the lapacho tree, shows both antimicrobial and antiviral activity.

S9278

Saikosaponin C

Saikosaponin C is a triterpene saponin found in Bupleurum that exhibits antiviral and pro-angiogenic activities.

S4942

4-Hydroxy-3,5-dimethoxybenzyl alcohol

4-Hydroxy-3,5-dimethoxybenzyl alcohol (Syringic alcohol, Syringyl alcohol) is a kind of phenol with antiviral properties.

S5020

Tilorone dihydrochloride

Tilorone dihydrochloride is a broad-spectrum, orally active antiviral agent that activates interferon production. It has antitumor, anti-inflammatory properties.

S5016

Isoprinosine

Isoprinosine (Inosine pranobex, Immunovir, Groprinosin, Delimmun) is an immunopharmacologic agent with antiviral activities.

S9078

Epigoitrin

Epigoitrin (Goitrin, BA-51-090278), the main bioactive constituent of Radix isatidis, exerts antiviral, anticancer, and antithyroid activities.

S6067

2,4-dichlorobenzyl alcohol

2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections.

S2334

Oleanolic Acid

Oleanolic Acid (Caryophyllin) is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana, which exerts antitumor and antiviral properties.

2021, 134(8)jcs255273

2019, 21(6):522-527

2018, 10.1080/10286020.2018.1461087

S9099

Orientin

Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.

S9328

5,6,7-Trimethoxyflavone

5,6,7-Trimethoxyflavone (Baicalein Trimethyl Ether), methylations of the hydroxyl groups of oroxylin A or baicalein, has various pharmacological activities including antiviral, anticancer and antibacterial.

S9120

Scutellarein

Scutellarein (6-Hydroxyapigenin), extracted from the perennial herb Scutellaria lateriflora, has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities

S4518

Chloroxylenol

Chloroxylenol is a broad-spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus.

S9136

Neochlorogenic acid

Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.

S4408

Procodazole

Procodazole (Propazol, 2-Benzimidazolepropionic acid, 3-(1H-benzimidazole-2) propanoic acid) is used as a potentiator which is non-specific active immunoprotective against viral and bacterial infections.