Etoposide

For research use only. Not for use in humans.

製品コードS1225 別名:VP-16, VP-16213

Etoposide化学構造

CAS No. 33419-42-0

Etoposide (VP-16, VP-16213) is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity. Etoposide induces autophagy, mitophagy and apoptosis.

サイズ 価格(税別)  
10mM (1mL in DMSO) JPY 17100
JPY 13600
JPY 48400
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バルク問合せ

文献中Selleckの製品使用例(170)

製品安全説明書

Antineoplastic and Immunosuppressive Antibiotics阻害剤の選択性比較

生物活性

製品説明 Etoposide (VP-16, VP-16213) is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity. Etoposide induces autophagy, mitophagy and apoptosis.
ターゲット
Topo II [2]
(Cell-free assay)
体外試験

Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA, which induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. [1] Etoposide inhibits the growth of murine angiosarcoma cell line (ISOS-1) in a 5 days-period with IC50 of 0.25 μg/mL. Cell growth of normal murine microvascular endothelial cells (mECs) is less sensitive to Etoposide with IC50 of 10 μg/mL). [2] Etoposide treated for 6 hr inhibits colonies of tetraploid variant of the human leukemic lymphoblast line CCRF-CEM with IC50 of 0.6 μM. [3] Etoposide treated for 2 hr inhibits growth of human pancreatic cancer cell line Y1, Y3, Y5, Y19, YM. YS, and YT with IC50s of 300 μg/mL, 300 μg/mL, 300 μg/mL, 91 μg/mL, 0.68 μg/mL, 300 μg/mL, 300 μg/mL, and 260 μg/mL, respectively. [4] Etoposide exposed for 1 hr inhibits growth of human glioma cell lines CL5, G142, G152, G111, and G5 with IC50 of 8, 9, 9.8, 10, and 15.8 μg/mL respectively for 12 days. Under same condition, the IC90 value is attained in cell lines CL5, G152, G142, and G111 at 26, 27, 32, and 33 μg/mL. Etoposide inhibition of topoisomerase II is homogeneous for each cell. The average inhibition rates are 15%, 21.8%, 31.8%, 41.5%, and 49.5% for 1, 2, 4, 8, and 16 μg Etoposide, respectively. [5]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
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HT1080 Ml7RSpVv[3Srb36gRZN{[Xl? NI\5bJQxNjByMEGtNVAxKM7:TR?= NVXCdmpZOS1{NDDo M3[2fmROW00EoB?= M{fneYlv\HWlZYOgdE1xPTNqc3XyNVUqKGmwIHLveIghfGmvZT2gZY5lKGOxbnPlcpRz[XSrb36t[IVx\W6mZX70JI1idm6nch?= NWHMUHgyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwO|gxPjRpPkK1NFc5ODZ2PD;hQi=>
HT1080 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mn:xNE4xODBzLUGwNEDPxE1? MYGyOEBp M{L4eWROW00EoB?= MV\jZZV{\XNiYX6gbY5kemWjc3WgbY4hfGinIH71cYJmeiCxZjDj[YxteyCrbjDHNk9ONCC5aHns[UBl\WO{ZXHzbY5oKFNiYX7kJGcyKHCqYYPlJINmdGy| NG\5Oms9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC3PFA3PCd-MkWwO|gxPjR:L3G+
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DOHH-2 MmTJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXK0PEBp NHHvPWNKSzVyPUG5MlnDqM7:TR?= MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTB2OEKzOkc,OjVyNEiyN|Y9N2F-
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HH MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4r1ZVI1KGh? MmfQTWM2OD1zMESuO:Kh|ryP MnXLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyNEiyN|YoRjJ3MES4NlM3RC:jPh?=
HH NFnZN4RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV20PEBp MYTJR|UxRTR6LkdCpO69VQ>? MlHPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyNEiyN|YoRjJ3MES4NlM3RC:jPh?=
HH M{HKWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2i3RVczKGh? MonUTWM2OD1zND63xsDPxE1? NG[1SI89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC0PFI{Pid-MkWwOFgzOzZ:L3G+
HuT-78 M4TxeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkfuNlQhcA>? Mni5TWM2OD17LkRCpO69VQ>? NVfGZ29HRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwOFgzOzZpPkK1NFQ5OjN4PD;hQi=>
HuT-78 NFfncoZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYq0PEBp NIfrcG9KSzVyPUSuN:Kh|ryP NEPh[Ic9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC0PFI{Pid-MkWwOFgzOzZ:L3G+
HuT-78 MkjBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3Xrd|czKGh? NYLrXZJoUUN3ME20MlLDqM7:TR?= NGfoXlc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC0PFI{Pid-MkWwOFgzOzZ:L3G+
OPM-2 NGewOoJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnfINlQhcA>? MnP4TWM2OD1{ND6xxsDPxE1? NELkUZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC0PFI{Pid-MkWwOFgzOzZ:L3G+
OPM-2 M3rvOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Mli5OFghcA>? M3TES2lEPTB;NNMg{txO NU\YTJZERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwOFgzOzZpPkK1NFQ5OjN4PD;hQi=>
OPM-2 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYj5XndtPzJiaB?= NGe0UFhKSzVyPUGuN:Kh|ryP M2TDTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MES4NlM3Lz5{NUC0PFI{PjxxYU6=
RPMI-8226 NELuSFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NX[1[2wyOjRiaB?= MVPJR|UxRTFyNj62xsDPxE1? MmGyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyNEiyN|YoRjJ3MES4NlM3RC:jPh?=
RPMI-8226 MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mme3OFghcA>? NIe3TFlKSzVyPUmxMlHDqM7:TR?= M1G3PVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MES4NlM3Lz5{NUC0PFI{PjxxYU6=
RPMI-8226 NHjhT2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH23fW04OiCq NEPmXWtKSzVyPUG0MlnDqM7:TR?= MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTB2OEKzOkc,OjVyNEiyN|Y9N2F-
U-266 MnHsS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4q1RVI1KGh? MlHkTWM2OD16Nj6yxsDPxE1? NHTjN|U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC0PFI{Pid-MkWwOFgzOzZ:L3G+
U-266 MnvkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVG4SGx3PDhiaB?= NV:2[2oxUUN3ME22PE41yqEQvF2= MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTB2OEKzOkc,OjVyNEiyN|Y9N2F-
U-266 MmSzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MXy3NkBp NF64PHdKSzVyPUK3MlTDqM7:TR?= M3rVTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MES4NlM3Lz5{NUC0PFI{PjxxYU6=
Kelly NWOySJp7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYOwMVExKM7:TR?= M3npV|czyqCq MULJR|UxRTFwNUG4xsDPxE1? NY\GXGNmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwNFg6ODBpPkK1NFA5QTByPD;hQi=>
SH-SY5Y  NH3WXXFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnHXNE0yOCEQvF2= NWXJUmRTPzMEoHi= MV7JR|UxRTBwN{W0xsDPxE4EoB?= MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTByOEmwNEc,OjVyMEi5NFA9N2F-
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SK-N-DZ NYHTTWprT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MonZNE0yOCEQvF2= NHz3SXM4OsLiaB?= NYHpd|JZUUN3ME21MlQ5PcLizszN NWLNOWxjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwNFg6ODBpPkK1NFA5QTByPD;hQi=>
HepG2 MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MlvCOFjDqGh? NYjiPXhITE2VT9Mg NITHe|JKSzVyPUGzMlY2yqEEsdMgNE46OsLizszN NGHpeHE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm5OlE{Pid-MkS5PVYyOzZ:L3G+
A549 M2D6dGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnrHOFjDqGh? MYTEUXNQyqB? M{\HZWlEPTB;MkSxMlnDqMLzwrCzNU4zO8LizszN Ml7HQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7OU[xN|YoRjJ2OUm2NVM3RC:jPh?=
MCF7 M1:3[mdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnXwOFjDqGh? M4TLRmROW00EoB?= MknnTWM2OD16MT6wPeKhyrIEoEG0MlIyyqEQvF2= M1fCTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUm2NVM3Lz5{NEm5OlE{PjxxYU6=
HL-60  MXLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFPQWVc4OsLiaB?= NV\FOYl7UUN3ME2wMlEz6oDHzszN M3T2UFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUmzNFE1Lz5{NEm5N|AyPDxxYU6=
HL-60[R] NFnp[JRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUjwOG9rPzMEoHi= MVXJR|UxRTNwMUNihKXPxE1? NEHoZ|c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm5N|AyPCd-MkS5PVMxOTR:L3G+
MIAPACA MmryS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHu1XoJIUTVyPUGuN{DDuSByLkCzJO69VQ>? M4DzdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUWzPFIyLz5{NEm1N|gzOTxxYU6=
MCF-7 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYLN[3FMT0l3ME2wMlI2KMLzIECuNUDPxE1? MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl3M{iyNUc,OjR7NUO4NlE9N2F-
HeLa M3fXZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NX3EeZZpT0l3ME2wMlY1KMLzIECuOEDPxE1? MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl3M{iyNUc,OjR7NUO4NlE9N2F-
MO59K  MkPqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2qwTFch\A>? M2\qfWlEPTB;MD6xO-KBjc7:TR?= NGnTOJM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm1N|U3OSd-MkS5OVM2PjF:L3G+
MO59J NUPqW5VST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkXzO{Bl M13HOmlEPTB;MD6x5qCG|ryP NI\rdJE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm1N|U3OSd-MkS5OVM2PjF:L3G+
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HL60/MX2 M4KwWmN6fG:2b4jpZ4l1gSCjc4PhfS=> NInobYk4OiCqcoO= MmLTR5l1d3SxeHnjbZR6KGGpYXnud5QhdWm2b4jhcpRzd26nLYLld4l{fGGwdDDoeY1idiCKTE[wM21ZOiClZXzsd{Bi\nSncjC3NkBpenNuIFnDOVAhRSB2OD61JO69VS5? NVKwZpE1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1NFc{PjhpPkG4OVA4OzZ6PD;hQi=>
HL60 NHy5boNEgXSxdH;4bYNqfHliYYPzZZk> MV23NkBpenN? NYjmcWc6S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEx4MDDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5{IN88UU4> NIjVOoI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEWwO|Q4Oid-MUi1NFc1PzJ:L3G+
HL60 M1\lN2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 M174T|Q5KGi{cx?= NGXlOVhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjMOlAh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuN|E2KM7:TT6= NVPwbm82RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1NVM6PzRpPkG4OVE{QTd2PD;hQi=>
K562 MkHqRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NVXIbpRXPDhiaILz NFm5N2lCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFu1OlIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGuNlch|ryPLh?= NVrTWo9yRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1NVQ6PzJpPkG4OVE1QTd{PD;hQi=>
KB M3fibmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M4ThfVQ5KGi{cx?= NIrqbYVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFvCJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLkSyJO69VS5? NUDZNGdCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1NVQ6PzJpPkG4OVE1QTd{PD;hQi=>
L02 M1rWfmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M1jmclQ5KGi{cx?= NXLWOotvSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDMNFIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGzJO69VS5? MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDVzNEm3Nkc,OTh3MUS5O|I9N2F-
DU145 ATCC HTB 81 MX\DfZRwfG:6aXPpeJkh[XO|YYm= NYqwfHNiPzJiaILz NYLRVZF[S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hTFVzNEWgRXRESyCKVFKgPFEh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGuOUDPxE1w MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDV3OES5NEc,OTh3NUi0PVA9N2F-
K562 ATCC CCL 243 MnHRR5l1d3SxeHnjbZR6KGG|c3H5 M1uzb|czKGi{cx?= MV\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLOVYzKEGWQ1OgR2NNKDJ2MzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPC57IN88UU4> M{nscFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NUW4OFkxLz5zOEW1PFQ6ODxxYU6=
MCF7 ATCC HTB 22 NIf6SpNEgXSxdH;4bYNqfHliYYPzZZk> Mn3aO|IhcHK| M{LuemN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiQWTDR{BJXEJiMkKgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF{LkKg{txONg>? Mn7aQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3NUi0PVAoRjF6NUW4OFkxRC:jPh?=
U251 RCB 0641 M4DIS2N6fG:2b4jpZ4l1gSCjc4PhfS=> M1\Hd|czKGi{cx?= M12y[WN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHUzPTFiUlPCJFA3PDFiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvPSEQvF2u MkDUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh3NUi0PVAoRjF6NUW4OFkxRC:jPh?=
3LL CRL 1642 NIDPPHJEgXSxdH;4bYNqfHliYYPzZZk> NWHQNolYPDhiaILz MV3DfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTCzUGwhS1KOIEG2OFIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IESg{txONg>? NVvXOpZzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1OVg1QTBpPkG4OVU5PDlyPD;hQi=>
L1210 ATCC CCL 219 MkDSR5l1d3SxeHnjbZR6KGG|c3H5 MYG0PEBpenN? NVPIOVNES3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVDF{MUCgRXRESyCFQ1ygNlE6KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCwMlUh|ryPLh?= MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDV3OES5NEc,OTh3NUi0PVA9N2F-
SK-Hep1 MlHvR5l1d3SxeHnjbZR6KGG|c3H5 NVLa[ZZ1S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0tvSHXwNUBk\WyuczDifUBOXFRiYYPzZZktKEmFNUCgQUA1QS54IN88UU4> MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZ|N{[4PEc,OTh4M{e2PFg9N2F-
HL60 MmjmR5l1d3SxeHnjbZR6KGG|c3H5 NFHGRWZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJVDZyIHPlcIx{KGK7IGPSRkBie3OjeTygTWM2OCB;IECuNkDPxE1w MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZ3MUe3NUc,OTh4NUG3O|E9N2F-
A549 NFrVOYFEgXSxdH;4bYNqfHliYYPzZZk> NUDNfZp4S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjc4Pld5Nm\CCjczDy[YR2[3Srb36gc4Yh[2WubDDndo94fGhiYomgV3JDKG2ndHjv[EwhUUN3MDC9JFkvQThizszNMi=> M3zHRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{iyOlY5Lz5zOEe4NlY3QDxxYU6=
KB Mkj4R5l1d3SxeHnjbZR6KGG|c3H5 MkXFR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT2Ih[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKG:oIHPlcIwh\3Kxd4ToJIJ6KFOUQjDt[ZRpd2RuIFnDOVAhRSBzND6yJO69VS5? NG\RU4Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEe4NlY3QCd-MUi3PFI3Pjh:L3G+
A549 MUXDfZRwfG:6aXPpeJkh[XO|YYm= M1jhOlczKGi{cx?= NGLwXJBEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA5NjN5IN88UU4> MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDh2NESyNkc,OTh6NES0NlI9N2F-
KB MnPlR5l1d3SxeHnjbZR6KGG|c3H5 M3nROVczKGi{cx?= MXXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLRkBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMT6yOUDPxE1w Mm\tQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh6NES0NlIoRjF6OES0OFIzRC:jPh?=
AGS NInSbplEgXSxdH;4bYNqfHliYYPzZZk> NV3RRlhwOyCmYYnz NXWzRo92S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSUeVIHPlcIx{KGGodHXyJFMh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjN4IN88UU4> NYO2eotQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNVMxPzRpPkG5NFE{ODd2PD;hQi=>
HL-60 NGXJ[XNEgXSxdH;4bYNqfHliYYPzZZk> NV7tfm9POyCmYYnz NVL1eoNDS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUExvNkCgZ4VtdHNiYX\0[ZIhOyCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwODFOwG0v M{n2b|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEGzNFc1Lz5zOUCxN|A4PDxxYU6=
J82 M3zhSmN6fG:2b4jpZ4l1gSCjc4PhfS=> NGOwXoY{KGSjeYO= M3PFeWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGo5OiClZXzsd{Bi\nSncjCzJIRigXNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNk45KM7:TT6= NXvwS|ZZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNVMxPzRpPkG5NFE{ODd2PD;hQi=>
MRC5 NFfV[pFEgXSxdH;4bYNqfHliYYPzZZk> MUezJIRigXN? NGDEdpNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOWkN3IHPlcIx{KGGodHXyJFMh\GG7czDifUBOXFRiYYPzZZktKEmFNUCgQUA{NjlizszNMi=> NVriNIZJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNVMxPzRpPkG5NFE{ODd2PD;hQi=>
SK-MES-1 NFz2WJNEgXSxdH;4bYNqfHliYYPzZZk> MVqzJIRigXN? Mn\QR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV2suVUWVLUGgZ4VtdHNiYX\0[ZIhOyCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJwNTFOwG0v M{L1SFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEGzNFc1Lz5zOUCxN|A4PDxxYU6=
A375 NFz6UmdEgXSxdH;4bYNqfHliYYPzZZk> M37zcWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE{PzViY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz65NkDPxE1w M1vq[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEO2OVg1Lz5zOUCzOlU5PDxxYU6=
A549 MmPoR5l1d3SxeHnjbZR6KGG|c3H5 M1P1Z2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iOT61NUDPxE1w MonwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyM{[1PFQoRjF7MEO2OVg1RC:jPh?=
HL60 M1foSGN6fG:2b4jpZ4l1gSCjc4PhfS=> MnnQR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGw3OCClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzLkizJO69VS5? NYrrNmlYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwN|Y2QDRpPkG5NFM3PTh2PD;hQi=>
THP1 MlLkR5l1d3SxeHnjbZR6KGG|c3H5 MY\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDUTHAyKGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJwMU[g{txONg>? NHLDVmQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUCzOlU5PCd-MUmwN|Y2QDR:L3G+
A549 M1O3emN6fG:2b4jpZ4l1gSCjc4PhfS=> NHKwNno4OiCqcoO= M2\3SGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFUvQSEQvF2u MkSzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO1NVQoRjF7MEWzOVE1RC:jPh?=
HL-60 NVPOV|J[S3m2b4TvfIlkcXS7IHHzd4F6 MmrvO|IhcHK| MU\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIUE03OCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNE4zPSEQvF2u NWjWN2hYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM2OTRpPkG5NFU{PTF2PD;hQi=>
U937 M1rhRmN6fG:2b4jpZ4l1gSCjc4PhfS=> M{nMfVczKGi{cx?= M3z0OmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHU6OzdiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvQTJizszNMi=> NWPUS4pnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM2OTRpPkG5NFU{PTF2PD;hQi=>
ACHN M3G2S2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NHfh[og6PiCqcoO= MlHzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCDQ1jOJINmdGy|IHHmeIVzKDl4IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{LkG1JO69VS5? M3r3WVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|Y4Lz5zOUC1N|c3PzxxYU6=
CCRF-CEM M1jZZmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NF7kR2k6PiCqcoO= Mk\PRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCFQ2LGMWNGVSClZXzsd{Bi\nSncjC5OkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNU4zKM7:TT6= NHHGOoE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC1N|c3Pyd-MUmwOVM4Pjd:L3G+
CCRF-SB NWnGe|djSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= Ml;5PVYhcHK| NXXvZ4k5SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDR3JHNVOEIHPlcIx{KGGodHXyJFk3KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjFizszNMi=> NU[2fHdMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4PjdpPkG5NFU{PzZ5PD;hQi=>
HeLa MnzMRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? Mn:4PVYhcHK| M2HiRWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDh[pRmeiB7NjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMzFOwG0v NEjuS|Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC1N|c3Pyd-MUmwOVM4Pjd:L3G+
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lung cancer cells NIWydmtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1\mblczKGi{cx?= NUD1PIVjT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hdHWwZzDjZY5k\XJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JJN2dG[xcnjv[IFucW6nIFKgZZN{[XluIFfJOVAhRSBzLkOg{txONg>? NWD5Z5JmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4PFQxQDlpPkKwPFg1ODh7PD;hQi=>
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HL60 MX\DfZRwfG:6aXPpeJkh[XO|YYm= MXO3NkBpenN? NVLWT|dPS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEx4MDDj[YxteyCjZoTldkA4OiCqcoOsJGlEPTBiPTCwMlQ5PiEQvF2u NIP5T4I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEm2NVc3Pyd-MkC5OlE4Pjd:L3G+
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502713 Mn7wRY51cWOjbnPldkBie3OjeR?= M3zr[|Q5KGi{cx?= NHfmbYlCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gOVAzPzF|IHPlcIx{KGG|c3Xzd4VlKGG|IHPlcIwhfmmjYnnsbZR6KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAxNjFizszNMi=> MmfaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyN{S0OFQoRjJzMEe0OFQ1RC:jPh?=
A549 Mn7MRY51cWOjbnPldkBie3OjeR?= NF;2Opc1QCCqcoO= M4ixPWFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCzMlA5KM7:TT6= NUjJNHF6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwO|Q1PDRpPkKxNFc1PDR2PD;hQi=>
DU145 NYXHZ4ZnSW62aXPhcoNmeiCjc4PhfS=> MUm0PEBpenN? MkfjRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFTVNVQ2KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCzMlch|ryPLh?= MkXhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyN{S0OFQoRjJzMEe0OFQ1RC:jPh?=
HCT15 NWXROY5YSW62aXPhcoNmeiCjc4PhfS=> NEPSXJE1QCCqcoO= NFnLWGVCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGNVOTViY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvQSEQvF2u NITWSGY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC3OFQ1PCd-MkGwO|Q1PDR:L3G+
Hep2 NYLJdXh[SW62aXPhcoNmeiCjc4PhfS=> M1e1ZVQ5KGi{cx?= NVXvS2lwSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGhmeDJiY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvQSEQvF2u NEnmbFE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC3OFQ1PCd-MkGwO|Q1PDR:L3G+
IMR32 NIfaPZFCdnSrY3HuZ4VzKGG|c3H5 NH;CS441QCCqcoO= MkTORY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFnNVlMzKGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTC2MlMh|ryPLh?= M1;RUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEe0OFQ1Lz5{MUC3OFQ1PDxxYU6=
PC3 MkS5RY51cWOjbnPldkBie3OjeR?= NFrqO|c1QCCqcoO= Mon0RY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGDDN{Bk\WyuczDhd5Nme3OnZDDhd{Bk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliU2LCJIF{e2G7LDDJR|UxKD1iMj62JO69VS5? NV[yZ4FTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwO|Q1PDRpPkKxNFc1PDR2PD;hQi=>
HT-29 NYLFZnAyS3m2b4TvfIlkcXS7IHHzd4F6 NIK4[5k4OiCqcoO= MojyR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTHQuOjliY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhT0l3MDC9JFMyNjZ{IN88UU4> NVj6XJFyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxNVUzOTBpPkKxNVE2OjFyPD;hQi=>
K562 NH7vSFZEgXSxdH;4bYNqfHliYYPzZZk> MlzNO|IhcHK| NID3PYpEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMPTZ{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEeLNUCgQUAyOi53OTFOwG0v MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTFzNUKxNEc,OjFzMUWyNVA9N2F-
MCF7 NGfvWZdEgXSxdH;4bYNqfHliYYPzZZk> MUK3NkBpenN? NUTXU5VVS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCJSUWwJF0hOTlwOUWg{txONg>? M2HiSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUG1NlExLz5{MUGxOVIyODxxYU6=
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PC3 MXPDfZRwfG:6aXPpeJkh[XO|YYm= NEn6UIk4OiCqcoO= MlO5R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJHRIUSB;IEOuPVgh|ryPLh?= NITJNYE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUGxOVIyOCd-MkGxNVUzOTB:L3G+
DU145 M3fIXmN6fG:2b4jpZ4l1gSCjc4PhfS=> MVjDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDEWVE1PSClZXzsd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzLkS0JO69VS5? Mlm5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFzMUWyOFYoRjJzMUG1NlQ3RC:jPh?=
HCT15 Mm[wR5l1d3SxeHnjbZR6KGG|c3H5 NYfONlZDS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUEOWMUWgZ4VtdHNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNk4xOyEQvF2u NVH3THJNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxNVUzPDZpPkKxNVE2OjR4PD;hQi=>
K562 MluyR5l1d3SxeHnjbZR6KGG|c3H5 NFrObItEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMPTZ{IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGuNlEh|ryPLh?= MnPrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFzMUWyOFYoRjJzMUG1NlQ3RC:jPh?=
MCF7 MX7DfZRwfG:6aXPpeJkh[XO|YYm= NVrMbYlSS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxMlk5KM7:TT6= NIDmb3o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUGxOVI1Pid-MkGxNVUzPDZ:L3G+
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HepG2 M3\s[WN6fG:2b4jpZ4l1gSCjc4PhfS=> NVK4PGJ1S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvQCEQvF2u MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTF5NESwPEc,OjFzN{S0NFg9N2F-
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SK-MEL-2 M4jVUGN6fG:2b4jpZ4l1gSCjc4PhfS=> M2TvO2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNMNU2HTD2yJINmdGy|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFEvOTdizszNMi=> M3zwZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUiyNlU5Lz5{MUG4NlI2QDxxYU6=
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XF498 M{nWZ2N6fG:2b4jpZ4l1gSCjc4PhfS=> MlT6R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gXGY1QThiY3XscJMh[nliU2LCJIF{e2G7LDDJR|UxKD1iMT63NkDPxE1w MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTF6MkK1PEc,OjFzOEKyOVg9N2F-
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