Fluorouracil (5-Fluorouracil, 5-FU)

For research use only. Not for use in humans.

製品コードS1209 別名:NSC 19893

Fluorouracil (5-Fluorouracil, 5-FU)化学構造

CAS No. 51-21-8

Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.

サイズ 価格(税別)  
10mM (1mL in DMSO) JPY 24200
JPY 26400
JPY 38500
最寄りの販売代理店を探す

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バルク問合せ

文献中Selleckの製品使用例(116)

製品安全説明書

DNA/RNA Synthesis阻害剤の選択性比較

生物活性

製品説明 Fluorouracil (5-Fluorouracil, 5-FU, NSC 19893) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS) in tumor cells. Fluorouracil induces apoptosis and can be used in the treatment of HIV.
ターゲット
Thymidylate synthase [1]
(Tumor cells)
体外試験

Adrucil is an analogue of uracil with a fluorine atom at the C-5 position in place of hydrogen. It rapidly enters the cell using the same facilitated transport mechanism as uracil. Adrucil is converted intracellularly to several active metabolites: fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine triphosphate (FUTP). The Adrucil metabolite FdUMP binds to the nucleotide-binding site of TS, forming a stable ternary complex with the enzyme and CH2THF, thereby blocking binding of the normal substrate dUMP and inhibiting dTMP synthesis. Metabolite of Adrucil also can be misincorporated into DNA, leading to DNA strand breaks and cell death. The pro-apoptosis effects of Adrucil may be related to its activation of tumor suppressor p53. Loss of p53 function reduces cellular sensitivity to Adrucil. [1] Adrucil is able to inhibit the survival and induce apoptosis of a board range of cancer cells. Adrucil suppresses viabilities of the nasopharyngeal carcinoma cell line CNE2 and HONE1 [2], pancreatic cancer cell lines Capan-1 [3], and human colon carcinoma cell line HT-29 [4] with IC50 of 9 μg/mL, 3 μg/mL, 0.22 μM, 2.5 μM, respectively.

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H292 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NV3kb2J5PzMEoHlCpC=> MlnTTWM2OD5iMkWg{txoN22O MmHCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWxO|YoRjJ2MEm1NVc3RC:jPh?=
HL-60 M1LpdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWDvbndIPzMEoHlCpC=> MmPzTWM2OD16Lk[wNUDPxGdxbVy= MkG2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWxO|YoRjJ2MEm1NVc3RC:jPh?=
HT-29 MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NX;qXldOPzMEoHlCpC=> NVfkcGZlUUN3ME6gNlUh|rypL33M MoLhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWxO|YoRjJ2MEm1NVc3RC:jPh?=
MCF-7 M2fvW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1X4UFczyqCqwrC= NXT4XWdyUUN3ME2yNEDPxGdxbVy= NV\zZZhwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwPVUyPzZpPkK0NFk2OTd4PD;hQi=>
L1210/0 NWPEemQ{TnWwY4Tpc44h[XO|YYm= NX\rblFbTW[oZXP0JI9vKExzMkGwM|Ah[2WubIOgbY4h[3WudIXy[UwhUUN3MDC9JFAvOyEQvF2u NYDzPIRYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2NlI4QCd-MkO2NlI4QDxxYU6=
CCRF-CEM Mny1SpVv[3Srb36gZZN{[Xl? Mk\HSYZn\WO2IH;uJGNEWkZvQ1XNJINmdGy|IHnuJIN2dHS3cnWsJGlEPTBiPTCyJO69VS5? NF:2Rmg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[yNlc5Lz5{M{[yNlc5RC:jPh?=
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HT-29 MnvsRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NUPBVVVDQTZiaILz M1n2S2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSGStNlkh[2WubIOgZYZ1\XJiOU[gbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuOlkh|ryPLh?= NH[5UYY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{e4OFQ6Lz5{N{e4OFQ6RC:jPh?=
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NCI/ADR-RES M2PvOGFvfGm2dX3vdkBie3OjeR?= M17RemFvfGm2dX3vdkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF7DTU9CTFJvUlXTJINmdGy|LDDHTVUxKD1iM{muPFExPyEQvF2u NHf6OZo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0OlA4Pyd-MUe0OFYxPzd:L3G+
SW480 M1jOdGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MWi3NkBpenN? NVXiSmRQSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTW|Q5OCClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKG2ndHjv[EwhUUN3MDC9JFgvOSEQvF2u NWjYdYRHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1NlQ3PTVpPkG3OVI1PjV3PD;hQi=>
MDA-MB-435S M2XqeWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 M{SyN|czKGi{cx?= NVuw[|B2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvNEO1V{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJI1mfGixZDygTWM2OCB;IEG0MlUh|ryPLh?= M{m0elxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUK0OlU2Lz5zN{WyOFY2PTxxYU6=
HCCLM7 MVfBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NU\ZboZrPzJiaILz MW\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEiFQ1zNO{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJI1mfGixZDygTWM2OCB;IEG4MlYh|ryPLh?= M2rle|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUK0OlU2Lz5zN{WyOFY2PTxxYU6=
Caco-2 MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXzHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDDZYNwNTJiY3XscJMtKEmFNUCgQUAyNjVizszNMi=> M2TQU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUS4NVI6Lz5zN{W0PFEzQTxxYU6=
MCF7 M33hPWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MoTSO|IhcHK| MojzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCPQ1[3JINmdGy|IHHmeIVzKDd{IHjyd{whUUN3MDC9JFAvOyEQvF2u Mnr3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEixPVgoRjF5NUS4NVk5RC:jPh?=
HCT116 MU\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? Ml\iO|IhcHK| NXjlRZhYSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDIR3QyOTZiY3XscJMh[W[2ZYKgO|IhcHK|LDDJR|UxKD1iMj64JO69VS5? MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV2OEG5PEc,OTd3NEixPVg9N2F-
SW480 NXLyd|lTSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MXW3NkBpenN? MlfZRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCVV{S4NEBk\WyuczDh[pRmeiB5MjDodpMtKEmFNUCgQUA{NjVizszNMi=> MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV2OEG5PEc,OTd3NEixPVg9N2F-
SW48 MVPBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? M4fKOFczKGi{cx?= NI[1SVRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIGPXOFgh[2WubIOgZYZ1\XJiN{KgbJJ{NCCLQ{WwJF0hPS5|IN88UU4> MmH4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEixPVgoRjF5NUS4NVk5RC:jPh?=
DLD1 NVrEb4s1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1;YbWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGRNTDFiY3XscJMtKEmFNUCgQUA1NjVizszNMi=> MmD1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NUO2PFUoRjF5NUWzOlg2RC:jPh?=
Caco-2 M{Pjb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX6xNEBl[Xm| M3q4TWdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGNi[29vMjDj[YxteyCjZoTldkAyOCCmYYnzMEBKSzVyIE2gNU42KM7:TT6= Mof6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NUW5OlkoRjF5NUW1PVY6RC:jPh?=
colon cancer cell NYXUcGhPS3m2b4TvfIlkcXS7IHHzd4F6 NGjpPIZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBkd2yxbjDjZY5k\XJiY3XscJMtKEeLNUCgQUA2Njd3IN88UU4> MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV4MkO2OUc,OTd3NkKzOlU9N2F-
A549 M365[mN6fG:2b4jpZ4l1gSCjc4PhfS=> M3HqUVQ5KGi{cx?= NFjsXGVEgXSxdH;4bYNqfHliYXfhbY5{fCCDNUS5JINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB7LkKg{txONg>? NUjZZZh{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2NFQ{QTRpPkG3OlA1Ozl2PD;hQi=>
L1210 MUXDfZRwe3SjdHnjJIFkfGm4aYT5JIF{e2G7 MmLGR5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JI1wfXOnIFyxNlExKGOnbHzzMEBKSzVyIE2gNE4zQCEQvF2u MkjuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7M{G4OlIoRjF5OUOxPFYzRC:jPh?=
CEM M3;iPGN6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= MUHDfZRwe3SjdHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1XNJINmdGy|LDDJR|UxKD1iOTFOwG0v M4fsUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUOxPFYzLz5zN{mzNVg3OjxxYU6=
Molt4/C8 Mn3uR5l1d3O2YYTpZ{Bi[3Srdnn0fUBie3OjeR?= NFr6TXhEgXSxc4TheIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUY9tfDRxQ{igZ4VtdHNuIFnDOVAhRSB{MzFOwG0v MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzl|MUi2Nkc,OTd7M{G4OlI9N2F-
Caco-2 Moe0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYPv[II3OTBiZHH5dy=> M4joS2dzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGNi[29vMjDj[YxteyCjZoTldkAyOCCmYYnzMEBKSzVyIE2gNU42KM7:TT6= M3HISFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MEO3NVk2Lz5zOECzO|E6PTxxYU6=
MCF7 NV7UdIN5SW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MoLVN{Bl[Xm| NUX3eYVsSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEOg[IF6eyCkeTDTVmIh[XO|YYmsJGlEPTBiPTC0MlMzKM7:TT6= NIfBXHA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEC2PVA6Oyd-MUiwOlkxQTN:L3G+
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embryonic cell MWTGeY5kfGmxbjDhd5NigQ>? NXXKZ2MzUW6mdXP0bY9vKG:oIHPs[YF3[WenIHHydoV{fCCrbjDlcYJzgW:waXOgZ4VtdHNib3[gd5Ri\2ViODDY[Y5weHW|IHzh[ZZqeyCkbHHzeJVt[WVuIFnDOVAhRSB{Nj64JO69VS5? NVHjSoFwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiyO|E2PThpPkG4NlcyPTV6PD;hQi=>
HepG2 NV:5PYJiS3m2b4TvfIlkcXS7IHHzd4F6 M1TXe2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{NCCLQ{WwJF0hOThwNzFOwG0v NH;xeW09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOwNlM{Pid-MUizNFI{OzZ:L3G+
L1210 MYXBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NGPm[pAzKGSjeYO= M{PQOGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViTEGyNVAh[2WubIOgZYZ1\XJiMjDkZZl{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuOlkh|ryPLh?= NFzSUnE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOESyOFE2PSd-MUi0NlQyPTV:L3G+
MCF7 M1\IdmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NVvSbopIOyCmYYnz MV;BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhOyCmYYnzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDRwNTFOwG0v MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR{NEG1OUc,OTh2MkSxOVU9N2F-
MiaPaCa2 NWP5OGVzSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MXSzJIRigXN? MWjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2rYWDhR4EzKGOnbHzzJIFnfGW{IEOg[IF6eyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC2MlUh|ryPLh?= M4PGS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEK0NVU2Lz5zOESyOFE2PTxxYU6=
SW620 M{n3fmFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MWWzJIRigXN? M2\4e2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2e2NlAh[2WubIOgZYZ1\XJiMzDkZZl{KGK7IF3UWEBie3OjeTygTWM2OCB;IEiuO{DPxE1w MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR{NEG1OUc,OTh2MkSxOVU9N2F-
HepG2 M1vjS2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 M3zzOlMh\GG7cx?= M4mwOmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXwS|Ih[2WubIOgZYZ1\XJiMzDkZZl{KGK7IF3UWEBie3OjeTygTWM2OCB;IEmuNkDPxE1w NVzSOIpLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0NlQyPTVpPkG4OFI1OTV3PD;hQi=>
CEM M{j6U2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 NH\1OY0{KGSjeYO= M3TZdGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQ1XNJINmdGy|IHHmeIVzKDNiZHH5d{BjgSCPVGSgZZN{[XluIFnDOVAhRSB7LkKzJO69VS5? MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR{NEG1OUc,OTh2MkSxOVU9N2F-
WI38 M{DFdGN6fG:2b4jpZ4l1gSCjc4PhfS=> MVuzJIRigXN? NVi2R3c5S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hX0l|ODDj[YxteyCjZoTldkA{KGSjeYOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTBizszNMi=> M4LqZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEK0NVU2Lz5zOESyOFE2PTxxYU6=
HeLa MnHpRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NIW0[Ws{KGSjeYO= M2rHS2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iSHXMZUBk\WyuczDh[pRmeiB|IHThfZMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMU[g{txONg>? NITBN2Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOESyOFE2PSd-MUi0NlQyPTV:L3G+
Molt4/C8 M{PaPGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 Mln5N{Bl[Xm| M{DUPWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTX;seFQwSzhiY3XscJMh[W[2ZYKgN{Bl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIxKM7:TT6= NE[zdlQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOESyOFE2PSd-MUi0NlQyPTV:L3G+
colon 26-L5 MYnDfZRwfG:6aXPpeJkh[XO|YYm= M1K3blczKGi{cx?= NXziUIYzS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4Uh[2:ub36gNlYuVDViY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvPDZizszNMi=> MoTBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NECyN|MoRjF6NESwNlM{RC:jPh?=
HeLa MW\DfZRwfG:6aXPpeJkh[XO|YYm= MoTQO|IhcHK| NGPqN4dEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjd5IN88UU4> MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR2MEKzN{c,OTh2NECyN|M9N2F-
LLC NYP0S4VNS3m2b4TvfIlkcXS7IHHzd4F6 MofTO|IhcHK| NWT3T5RyS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVEyFIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzNjV7IN88UU4> M4DGb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NESwNlM{Lz5zOES0NFI{OzxxYU6=
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CCRF-CEM NEPReJlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mm\QOFghcHK| NUj0N4dNT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hS0OURj3DSW0h[2WubIOgZYZ1\XJiNEigbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUA6Njd5MkO3JO69VS5? NVGwPWNxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVAzODRpPkKwPFUxOjB2PD;hQi=>
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BT549 MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mln4OFghcHK| NEfYTHpIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBDXDV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEGwMlcyPTJizszNMi=> MnrRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUCyNFQoRjJyOEWwNlA1RC:jPh?=
OVCAR5 NU\pbmxyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHe0VVQ1QCCqcoO= M3S4[Wdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GUNTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygS2k2OCB;IEGwMlk3PDhizszNMi=> MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh3MEKwOEc,OjB6NUCyNFQ9N2F-
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Patu-02 M1zEcmN6fG:2b4jpZ4l1gSCjc4PhfS=> NIjlWW9EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBR[XS3LUCyJINmdGy|IHL5JINzgXO2YXygeolwdGW2IIP0ZYlvcW6pLDDJR|UxKD1iMz65OUDPxE1w M3\xTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUOwNVI{Lz5{MEmzNFEzOzxxYU6=
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Patu-T NHPBNllEgXSxdH;4bYNqfHliYYPzZZk> NXWxNphkS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hPS2IVT3y[ZNqe3SjboSgVIF1fS2WIHPlcIx{KGK7IHPyfZN1[WxidnnvcIV1KHO2YXnubY5oNCCLQ{WwJF0hOzNwMjFOwG0v NYDr[ZJPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC5N|AyOjNpPkKwPVMxOTJ|PD;hQi=>
Hep2 MX;BcpRq[2GwY3XyJIF{e2G7 NF;TfHg1QCCqcoO= M3nnT2FvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZAzKGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCwMlMh|ryPLh?= MkTLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyN{S0OFQoRjJzMEe0OFQ1RC:jPh?=
A549 M4TR[WFvfGmlYX7j[ZIh[XO|YYm= MkC1OFghcHK| NUS5N5NRSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[XO|ZYPz[YQh[XNiY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFIvPCEQvF2u NHfDdmw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC3OFQ1PCd-MkGwO|Q1PDR:L3G+
HCT15 MmLERY51cWOjbnPldkBie3OjeR?= NWLaU3l6PDhiaILz MoHvRY51cWOjbnPldkBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjDWFE2KGOnbHzzJIF{e2W|c3XkJIF{KGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTBiPTCzMlYh|ryPLh?= M3q4dVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEe0OFQ1Lz5{MUC3OFQ1PDxxYU6=
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CEM/0 M{jXOGN6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= NH:2WWE4OiCqcoO= M3SzZ2N6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDSW0wOCClZXzsd{Bi\nSncjC3NkBpenNiYomgZ4VtdCClb4XueIlv\yxiSVO1NEA:KDF6IN88UU4> NV;HPY9qRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4PVI5OjlpPkKxPFkzQDJ7PD;hQi=>
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HeLa MnrBR5l1d3O2YYTpZ{Bi[3Srdnn0fUBie3OjeR?= MlT0R5l1d3O2YYTpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOsJGlEPTBiPTCwMlU1KM7:TT6= NYTxSIlIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG5NVc{PjNpPkKxPVE4OzZ|PD;hQi=>
CEM M{G1b2N6fG:|dHH0bYMh[WO2aY\peJkh[XO|YYm= M4rtN2N6fG:|dHH0bYMh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOsJGlEPTBiPTCxPEDPxE1w NXflZpNXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG5NVc{PjNpPkKxPVE4OzZ|PD;hQi=>
A549 MY\DfZRwfG:6aXPpeJkh[XO|YYm= M{OwUlMh\GG7cx?= M4fWZmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGE2PDliY3XscJMh[W[2ZYKgN{Bl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvPDJizszNMi=> NVnSOm1GRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwNFA6OjVpPkKyNFAxQTJ3PD;hQi=>
HepG2 NH2wRZBEgXSxdH;4bYNqfHliYYPzZZk> NUW0dllEOyCmYYnz MoPiR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgN{Bl[Xm|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFIvPyEQvF2u MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjByMEmyOUc,OjJyMEC5NlU9N2F-
BCG823 MUPDfZRwfG:6aXPpeJkh[XO|YYm= NYO0U|M4OyCmYYnz NVrwU4hiS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSkOJOEKzJINmdGy|IHHmeIVzKDNiZHH5d{BjgSCPVGSgZZN{[XluIFnDOVAhRSB4LkG1JO69VS5? MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjByMEmyOUc,OjJyMEC5NlU9N2F-
colon cancer cell MUHDfZRwfG:6aXPpeJkh[XO|YYm= M2DYWlQ5KGi{cx?= MY\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDjc4xwdiClYX7j[ZIh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IHPveYx1\XJiY3;1cpRqdmduIFfJOVAhRSB6LkSg{txONg>? M4njdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MEW2Nlc4Lz5{MkC1OlI4PzxxYU6=
leukemia cell MlLVR5l1d3SxeHnjbZR6KGG|c3H5 NUTrR45FPDhiaILz MoLUR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gcIV2c2WvaXGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KGOxdXz0[ZIh[2:3boTpcoctKEeLNUCgQUAyPS5zIN88UU4> MkDFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJyNU[yO|coRjJ{MEW2Nlc4RC:jPh?=
prostate cancer cell MoTZR5l1d3SxeHnjbZR6KGG|c3H5 NF;3dY81QCCqcoO= NYjmUFkxS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4heHKxc4TheIUh[2GwY3XyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSClb4XseIVzKGOxdX70bY5oNCCJSUWwJF0hOjJwNzFOwG0v MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB3NkK3O{c,OjJyNU[yO|c9N2F-
renal cancer cell NF30WmdEgXSxdH;4bYNqfHliYYPzZZk> NWnTflQ2PDhiaILz NXjQPWRQS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hemWwYXygZ4Fv[2W{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBkd3WudHXyJINwfW62aX7nMEBIUTVyIE2gOFUvPiEQvF2u MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB3NkK3O{c,OjJyNU[yO|c9N2F-
MCF7 M3e3eWFvfGmycn;sbYZmemG2aY\lJIF{e2G7 NIfEZ4Y4OiCqcoO= NGTacVhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEmuOlch|ryPLh?= NHi3[Jg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkC3PVM4QCd-MkKwO|k{Pzh:L3G+
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GLC82 MW\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MYG3NkBpenN? MWDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEeOQ{iyJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzNT61JO69VS5? MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB5OUO3PEc,OjJyN{mzO|g9N2F-
MGC803 MY\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MmPmO|IhcHK| MWLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2JQ{iwN{Bk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMU[uOkDPxE1w MonEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJyN{mzO|goRjJ{MEe5N|c5RC:jPh?=
CNE2 MWjBcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MnXYO|IhcHK| NYnVe5VkSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDDUmUzKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCxO{4zKM7:TT6= NVrheVVDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwO|k{PzhpPkKyNFc6Ozd6PD;hQi=>
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leukemia cell NEHlSIxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXm0PEBpenN? NWHqR49ET3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hdGW3a3XtbYEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IHPveYx1\XJiY3;1cpRmeiCvZYToc4QtKEeLNUCgQUAyPS5zIN88UU4> NUPhfINIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxNVkyPTFpPkKyNVE6OTVzPD;hQi=>
prostate cancer cell M3TkVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3\jUFQ5KGi{cx?= MXvHdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjDwdo9{fGG2ZTDjZY5k\XJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JINwfWy2ZYKgZ492dnSncjDt[ZRpd2RuIFfJOVAhRSB{Mj63JO69VS5? MoG1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzMUmxOVEoRjJ{MUG5NVUyRC:jPh?=
renal cancer cell M33meWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M37uWlQ5KGi{cx?= NWfoNIg4T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hemWwYXygZ4Fv[2W{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBkd3WudHXyJINwfW62ZYKgcYV1cG:mLDDHTVUxKD1iNEWuOkDPxE1w NIn2XVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkGxPVE2OSd-MkKxNVkyPTF:L3G+
H460 MU\DfZRwfG:6aXPpeJkh[XO|YYm= M2[xPFczKGi{cx?= NHjCRplEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJPDZyIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{KM7:TT6= NXjoZ2ZRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxN|AyOzJpPkKyNVMxOTN{PD;hQi=>
HCT116 MVXDfZRwfG:6aXPpeJkh[XO|YYm= MnrOO|IhcHK| Mkm0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1KM7:TT6= Mm\GQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzM{CxN|IoRjJ{MUOwNVMzRC:jPh?=
MCF7 NXPrO5Q1S3m2b4TvfIlkcXS7IHHzd4F6 MkOyO|IhcHK| NXPmVmRKS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTRizszNMi=> MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF|MEGzNkc,OjJzM{CxN|I9N2F-
A549 MVfDfZRwfG:6aXPpeJkh[XO|YYm= MkK2NlQhcHK| Ml20R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjCyOEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gOU43PCEQvF2u MoPyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzOEK5NlYoRjJ{MUiyPVI3RC:jPh?=
QGY7701 MXTDfZRwfG:6aXPpeJkh[XO|YYm= M3XrZVI1KGi{cx?= M1mxTWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHFIYTd5MEGgZ4VtdHNiYX\0[ZIhOjRiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDF2LkOg{txONg>? NVjFVFdSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxPFI6OjZpPkKyNVgzQTJ4PD;hQi=>
SW480 NHe2ellEgXSxdH;4bYNqfHliYYPzZZk> NWq2T4Q{OjRiaILz NEfu[oFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBUXzR6MDDj[YxteyCjZoTldkAzPCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTVwN{Gg{txONg>? NGjMO5U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkG4NlkzPid-MkKxPFI6OjZ:L3G+
HeLa MXrDfZRwfG:6aXPpeJkh[XO|YYm= NFj3XoMzPCCqcoO= NHjHZmxEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\UyjIHPlcIx{KGGodHXyJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPi5|MjFOwG0v MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF6MkmyOkc,OjJzOEK5NlY9N2F-
KB NUXyOZVXS3m2b4TvfIlkcXS7IHHzd4F6 NXLhT5ExPzJiaILz NGLyXllEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMSiClZXzsd{Bi\nSncjC3NkBpenNibomgUXRVKGG|c3H5MEBKSzVyIE2gPUDPxE1w MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjJyMESwOEc,OjJ{MEC0NFQ9N2F-
CNE2 MkPsR5l1d3SxeHnjbZR6KGG|c3H5 NV76NFVIPzJiaILz MYXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDUmUzKGOnbHzzJIFnfGW{IEeyJIhzeyCweTDNWHQh[XO|YYmsJGlEPTBiPTCxN{42KM7:TT6= MoXNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ{MEC0NFQoRjJ{MkCwOFA1RC:jPh?=
HepG2 M2G5UGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MkjrOFghcHK| NXGyNnFISW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gNVUvQTJizszNMi=> MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjJyOUS4Okc,OjJ{MEm0PFY9N2F-
NCI-H460 NFH1e2ZEgXSxdH;4bYNqfHliYYPzZZk> NHHtOVJEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBPS0lvSES2NEBk\WyuczygTWM2OCB;IEig{txONg>? NFjHWHo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkK4N|Q2OSd-MkKyPFM1PTF:L3G+
SMMC7721 MoPqR5l1d3SxeHnjbZR6KGG|c3H5 NYXlU3ZHS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW02PQ{e3NlEh[2WubIOsJGlEPTBiPTCxOUDPxE1w NH;NW5E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkK4N|Q2OSd-MkKyPFM1PTF:L3G+
MCF7 NUfCXXRrS3m2b4TvfIlkcXS7IHHzd4F6 MoTKR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{whUUN3MDC9JFMyKM7:TT6= M{DiOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MkizOFUyLz5{MkK4N|Q2OTxxYU6=
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BGC823 NUHSZW46S3m2b4TvfIlkcXS7IHHzd4F6 NGXMZno4OiCqcoO= MoHTR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRmdEQDJ|IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1NjVizszNMi=> M3XUZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{K3OFQ2Lz5{MkeyO|Q1PTxxYU6=
HepG2 NYXLZ|FNS3m2b4TvfIlkcXS7IHHzd4F6 MW[3NkBpenN? MoXER5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFQvQCEQvF2u NEnkb4U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkeyO|Q1PSd-MkK3Nlc1PDV:L3G+
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GLC82 NHO2fIZEgXSxdH;4bYNqfHliYYPzZZk> MnrBO|IhcHK| MmX0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gS2xEQDJiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE4NjRizszNMi=> NGjhWZI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mke0PVE6Oid-MkK3OFkyQTJ:L3G+
MGC803 MV7DfZRwfG:6aXPpeJkh[XO|YYm= MVq3NkBpenN? MYnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNS2M5ODNiY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFE5NjVizszNMi=> MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjd2OUG5Nkc,OjJ5NEmxPVI9N2F-
MCF7 MU\BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? NE\WPIE4OiCqcoO= MY\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KGO{eYP0ZYwhfmmxbHX0JJN1[WmwaX7nJI1mfGixZDygTWM2OCB;IESuO{DPxE1w NUTYWoRLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK3OlU5QTdpPkKyO|Y2QDl5PD;hQi=>
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A375-S2 NXrlbIZWS3m2b4TvfIlkcXS7IHHzd4F6 MmnqR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVM4PS2VMjDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTC5MlkzKM7:TT6= MnjjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
HeLa Mnv1R5l1d3SxeHnjbZR6KGG|c3H5 M13WWGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUCuN|Yh|ryPLh?= MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjhyMU[0OEc,OjJ6MEG2OFQ9N2F-
HepG2 Ml2zR5l1d3SxeHnjbZR6KGG|c3H5 M3LMXWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEGwMlQ2KM7:TT6= MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjhyMU[0OEc,OjJ6MEG2OFQ9N2F-
BGC823 MnzkR5l1d3SxeHnjbZR6KGG|c3H5 Mly4R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRmdEQDJ|IHPlcIx{KGK7IF3UWEBie3OjeTygTWM2OCB;IEG1MlY2KM7:TT6= Mnz6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
Hep2 M1LQPGN6fG:2b4jpZ4l1gSCjc4PhfS=> NYW1UZVyS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyMjDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyOE42QCEQvF2u MmG2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6MEG2OFQoRjJ{OECxOlQ1RC:jPh?=
MCF7 M4ezNmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVfwenJkS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCkeTDNWHQh[XO|YYmsJGlEPTBiPTCyOE42QCEQvF2u NIfYflI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkiwNVY1PCd-MkK4NFE3PDR:L3G+
A549 MXrDfZRwfG:6aXPpeJkh[XO|YYm= MYXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDNzLkWyJO69VS5? NVX2d5g2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFE3PDRpPkKyPFAyPjR2PD;hQi=>
MDA231 MXzDfZRwfG:6aXPpeJkh[XO|YYm= NVTrOFJXS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUSDMkOxJINmdGy|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFMyNjV5IN88UU4> NXzsZ|ZiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NFE3PDRpPkKyPFAyPjR2PD;hQi=>
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MKN45 NY\rfldYS3m2b4TvfIlkcXS7IHHzd4F6 MVG0PEBpenN? NFraSIREgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOU052NTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPDFwN{Og{txONg>? NHrQTXI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkiwPVU2QCd-MkK4NFk2PTh:L3G+
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LoVo M{T3[GFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MWK0PEBpenN? M{K2V2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTH;Wc{Bk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMz6zJO69VS5? NWPUWGxpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4OFA1QTNpPkKyPFQxPDl|PD;hQi=>
A549 NIfyc|FCdnSrcILvcIln\XKjdHn2[UBie3OjeR?= MoLNOFghcHK| M33Md2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMUKuPEDPxE1w Mn\wQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6NEC0PVMoRjJ{OESwOFk{RC:jPh?=
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2008 NUn5UlNDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MX\Hdo94fGhiaX7obYJqfGmxbjDv[kBpfW2jbjCyNFA5KGOnbHzzJIJ6KGO{eYP0ZYwhfmmxbHX0JIF{e2G7LDDJR|UxKD1iND6yJO69VS5? MmqyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyN{W0NVQoRjJ|MEe1OFE1RC:jPh?=
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MCF7 MVfDfZRwfG:6aXPpeJkh[XO|YYm= NHr5[|M4OiCqcoO= NIrQcoNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAyPy5{IN88UU4> MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzJ5OUi2OEc,OjN{N{m4OlQ9N2F-
HepG2 MV;DfZRwfG:6aXPpeJkh[XO|YYm= M1vTXlczKGi{cx?= NWrKXIczS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJzLkmg{txONg>? NXP6TohCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyO|k5PjRpPkKzNlc6QDZ2PD;hQi=>
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B16F10 M2rhe2FvfGmlYX7j[ZIh[XO|YYm= Mnf2OFghcHK| NVj6bYZMSW62aXPhcoNmeiCjY4Tpeol1gSCjZ3HpcpN1KG2xdYPlJGIyPkZzMDDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKHO3co\peoFtKG2nYYP1doVlKGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzOS52MTFOwG0v NX76dI9mRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOzNVI6PDlpPkKzN|EzQTR7PD;hQi=>
SGC7901 MXrBcpRq[2GwY3XyJIF{e2G7 NYfSdYRMPDhiaILz NIX4PZBCdnSrY3HuZ4VzKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gV2dEPzlyMTDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKHO3co\peoFtKG2nYYP1doVlKGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA1Pi5|NTFOwG0v MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzNzMkm0PUc,OjN|MUK5OFk9N2F-
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MCF7 NVW3OJhDS3m2b4TvfIlkcXS7IHHzd4F6 NWjoXZF[PzJiaILz MXPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIF{e2W|c3XkJIF{KGe{b4f0bEBqdmirYnn0bY9vKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA4NjV2IN88UU4> NIPZUGo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{O1N|c1Oyd-MkOzOVM4PDN:L3G+
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leukemia Ml3WR5l1d3SxeHnjbZR6KGG|c3H5 M2\k[VQ5KGi{cx?= NFroRVFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBt\XWtZX3pZUBk\WyuczDh[pRmeiB2ODDodpMh[nlic4XsdIhwemixZHHtbY5mKEJiYYPzZZktKEeLNUCgQUAyPS5zIN88UU4> NVXjXHhTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO0O|Q5QTlpPkKzOFc1QDl7PD;hQi=>
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SGC7901 MX7DfZRwfG:6aXPpeJkh[XO|YYm= NYXzeVRTPDhiaILz NYe5VG9kS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0eFN{mwNUBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMkiuPUDPxE1w NYOzU|lIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO0PVAyPTlpPkKzOFkxOTV7PD;hQi=>
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MCF7 NXjCTYI2S3m2b4TvfIlkcXS7IHHzd4F6 NX\JO2ViPDhiaILz NVOwOJlHS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOTFwNTFOwG0v MnzOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN3NUiyN|goRjJ|NUW4NlM5RC:jPh?=
K562 Ml\1R5l1d3SxeHnjbZR6KGG|c3H5 NF:ySZQ1QCCqcoO= M{H0ZmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGs2PjJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI{NjV3IN88UU4> NHXrTHc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{W1PFI{QCd-MkO1OVgzOzh:L3G+
U937 M4HucmN6fG:2b4jpZ4l1gSCjc4PhfS=> M3;2PVQ5KGi{cx?= M{HuWmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHU6OzdiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFI{Njl|IN88UU4> M3rad|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUW4NlM5Lz5{M{W1PFI{QDxxYU6=
HCT116 MlLkR5l1d3SxeHnjbZR6KGG|c3H5 MYG0PEBpenN? MoHPR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzPy55NjFOwG0v M2\HW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUW4NlM5Lz5{M{W1PFI{QDxxYU6=
HT1080 Ml7lR5l1d3SxeHnjbZR6KGG|c3H5 NWPoVohjPDhiaILz MXLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWFExQDBiY3XscJMh[W[2ZYKgOFghcHK|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFM2NjZ{IN88UU4> NFjjdmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{W1PFI{QCd-MkO1OVgzOzh:L3G+
HepG2 MULDfZRwfG:6aXPpeJkh[XO|YYm= NGna[WQ1QCCqcoO= NUXvdpRoS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDRyLkO0JO69VS5? MmLRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN3NUiyN|goRjJ|NUW4NlM5RC:jPh?=
A549 MkXVR5l1d3SxeHnjbZR6KGG|c3H5 MU[0PEBpenN? NYXjOopMS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPDRwMEWg{txONg>? NVfRT|RMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1OVgzOzhpPkKzOVU5OjN6PD;hQi=>
EC9706 MnuwR5l1d3SxeHnjbZR6KGG|c3H5 NHfw[oE4OiCqcoO= NFe2cVhEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBGSzl5ME[gZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwM{Kg{txONg>? M1LTT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkS0NVk{Lz5{M{[0OFE6OzxxYU6=
MGC803 MWDDfZRwfG:6aXPpeJkh[XO|YYm= M{OzNlczKGi{cx?= NULJeGFvS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUeFOECzJINmdGy|IHHmeIVzKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB5LkG0JO69VS5? NUjrU4FXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2OFQyQTNpPkKzOlQ1OTl|PD;hQi=>
MCF7 MXTDfZRwfG:6aXPpeJkh[XO|YYm= NVH6dXdiPzJiaILz NWPqOGZLS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hPy5|MzFOwG0v NUjn[GU{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2OFQyQTNpPkKzOlQ1OTl|PD;hQi=>
SMMC7721 NV\Qc3JIS3m2b4TvfIlkcXS7IHHzd4F6 NWmwN5BJPzJiaILz MoTTR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV21OSzd5MkGgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ4LkexJO69VS5? MmfWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NESxPVMoRjJ|NkS0NVk{RC:jPh?=
HCT116 MnzUR5l1d3SxeHnjbZR6KGG|c3H5 MX60PEBpenN? MlnlR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{KGGodHXyJFQ5KGi{czDifUB{fWyob4Loc4RidWmwZTDCJIF{e2G7LDDJR|UxKD1iND61NkDPxE1w MnHDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NESyNVUoRjJ|NkS0NlE2RC:jPh?=
HT-29 MUfDfZRwfG:6aXPpeJkh[XO|YYm= MVe0PEBpenN? NIHJOXpEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXC1{OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBie3OjeTygTWM2OCB;IE[uN|Uh|ryPLh?= NVvW[npRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2OFQzOTVpPkKzOlQ1OjF3PD;hQi=>
A549 NXzQRoxOSW62aYDyc4xq\mW{YYTpeoUh[XO|YYm= MWq3NkBpenN? MXvBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEF3NEmgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDNwNUKg{txONg>? NHHYW289[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[2OVExPid-MkO2OlUyODZ:L3G+
HCT116 MX3BcpRqeHKxbHnm[ZJifGm4ZTDhd5NigQ>? MWS3NkBpenN? Mm\5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKQ2SxNVYh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEWuOVMh|ryPLh?= MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ4NUGwOkc,OjN4NkWxNFY9N2F-
HT-29 MoLJRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? NVPDVY1iPzJiaILz Mle0RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCKVD2yPUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMkSuOUDPxE1w NVX5W|VqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2OlUyODZpPkKzOlY2OTB4PD;hQi=>
MCF7 M{XmNGFvfGmycn;sbYZmemG2aY\lJIF{e2G7 MoHwO|IhcHK| NH;jXJpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3DSlch[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEOyMlE5KM7:TT6= M1e0bFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Nk[1NVA3Lz5{M{[2OVExPjxxYU6=
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colon cancer MUTDfZRwfG:6aXPpeJkh[XO|YYm= NYe3b2NsPDhiaILz NWjTU3M4S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4h[2:ub36gZ4Fv[2W{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBkd3WudHXyJINwfW62ZYKgZY5idHm|aYOsJGdKPTBiPTC4MlQh|ryPLh?= MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ6M{W5Nkc,OjN4OEO1PVI9N2F-
leukemia NGDyWldEgXSxdH;4bYNqfHliYYPzZZk> NIjxWHU1QCCqcoO= MVzDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDs[ZVs\W2rYTDj[YxteyCjZoTldkA1QCCqcoOgZpkh[2:3bITldkBkd3WwdHXyJIFv[Wy7c3nzMEBIUTVyIE2gNVUvOSEQvF2u MlexQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4OEO1PVIoRjJ|NkizOVkzRC:jPh?=
prostate cancer MVPDfZRwfG:6aXPpeJkh[XO|YYm= MWG0PEBpenN? NWXw[nE3S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4heHKxc4TheIUh[2GwY3XyJINmdGy|IHHmeIVzKDR6IHjyd{BjgSClb4XseIVzKGOxdX70[ZIh[W6jbInzbZMtKEeLNUCgQUAzOi55IN88UU4> MlLVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4OEO1PVIoRjJ|NkizOVkzRC:jPh?=
renal cancer NXyyVVZQS3m2b4TvfIlkcXS7IHHzd4F6 MoTSOFghcHK| NIHzS2VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBz\W6jbDDjZY5k\XJiY3XscJMh[W[2ZYKgOFghcHK|IHL5JINwfWy2ZYKgZ492dnSncjDhcoFtgXOrczygS2k2OCB;IES1MlYh|ryPLh?= NYnLVY9kRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2PFM2QTJpPkKzOlg{PTl{PD;hQi=>
SH-SY5Y MoW1R5l1d3SxeHnjbZR6KGG|c3H5 NVvpS|hZPzJiaILz NXK4WGNSS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0hvU2m1XUBk\WyuczDh[pRmeiB5MjDodpMh[nliTWTUJIF{e2G7LDDJR|UxKD1iMD65O{DPxE1w MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ6NUW3NUc,OjN4OEW1O|E9N2F-
HCT116 M4HHXWN6fG:2b4jpZ4l1gSCjc4PhfS=> MmjlO|IhcHK| NHjRdVlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDNwMkSg{txONg>? M2XadlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Nki1OVcyLz5{M{[4OVU4OTxxYU6=
A549 NUL5Wod5S3m2b4TvfIlkcXS7IHHzd4F6 NILXbIU4OiCqcoO= MmHaR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyIE2gPE44OSEQvF2u NFrlNlY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[4OVU4OSd-MkO2PFU2PzF:L3G+
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HepG2 NV\1Z3Z3S3m2b4TvfIlkcXS7IHHzd4F6 MXO3NkBpenN? NWHZNHdCS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWyR{KgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDJ2Lkm2JO69VS5? NHPjNms9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[4OVU4OSd-MkO2PFU2PzF:L3G+
PC3 M3fSN2FvfGmycn;sbYZmemG2aY\lJIF{e2G7 MmXPO|IhcHK| MnLSRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCSQ{OgZ4VtdHNiZYjwdoV{e2mwZzDTT3AzKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAzPy5yNzFOwG0v NHz0fpE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{ezOVI5OSd-MkO3N|UzQDF:L3G+
PC3 MnjQRY51cXC{b3zp[oVz[XSrdnWgZZN{[Xl? MWe3NkBpenN? MYjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKFCFMzDj[YxteyCneIDy[ZN{cW6pIGDDSG5CKGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA{OS52NDFOwG0v M{GwNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|N{O1NlgyLz5{M{ezOVI5OTxxYU6=
COLO320DM Ml;pR5l1d3SxeHnjbZR6KGG|c3H5 MmntOFghcHK| Ml:zR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR29NVzN{MFTNJINmdGy|IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSB{IN88UU4> NV:yWGQxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO3PVI{PTJpPkKzO|kzOzV{PD;hQi=>
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