Staurosporine (AM-2282)

For research use only. Not for use in humans.

製品コードS1421 別名：Antibiotic AM-2282, STS

CAS No. 62996-74-1

Staurosporine (AM-2282, Antibiotic AM-2282, STS) is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM) in cell-free assays. Also shows inhibitory activities on other kinases, such as PKA, PKG, S6K, CaMKII, etc. Phase 3.

サイズ

価格(税別)

2mg	JPY 46800
5mg	JPY 85000
25mg	JPY 216560

最寄りの販売代理店を探す

東京
北海道
東北
北関東
南関東
東海
北信越
近畿
中国
四国
九州

お探しのディーラーが見当たらない場合は直接こちらのメールアドレスまでお問い合わせください：[email protected]

バルク問合せ

代表番号: 03-5615-9297|電子メール：[email protected]|よく尋ねられる質問

文献中Selleckの製品使用例(111)

製品安全説明書

Antineoplastic and Immunosuppressive Antibiotics阻害剤の選択性比較

生物活性

製品説明

ターゲット

PKCα ^[1] (Cell-free assay)	c-Fgr ^[2] (Cell-free assay)	phosphorylase kinase ^[2] (Cell-free assay)	PKCη ^[1] (Cell-free assay)	PKCγ ^[1] (Cell-free assay)	もっとクリックする
2 nM	2 nM	3 nM	4 nM	5 nM	もっとクリックする

体外試験

Staurosporine, a microbial alkaloid, significantly inhibits protein kinase C from rat brain with IC50 of 2.7 nM. Staurosporine displays strong inhibitory effect against HeLa S3 cells with IC50 of 4 nM. ^[1] Staurosporine also inhibits a variety of other protein kinases, including PKA, PKG, phosphorylase kinase, S6 kinase, Myosin light chain kinase (MLCK), CAM PKII, cdc2, v-Src, Lyn, c-Fgr, and Syk with IC50 of 15 nM, 18 nM, 3 nM, 5 nM, 21 nM, 20 nM, 9 nM, 6 nM, 20 nM, 2 nM, and 16 nM, respectively. ^[2] Staurosporine (1 μM) induces >90% apoptosis in PC12 cells. Consistently, Staurosporine treatment induces a rapid and prolonged elevation of intracellular free calcium levels [Ca²⁺]_i, accumulation of mitochondrial reactive oxygen species (ROS), and subsequent mitochondrial dysfunction. ^[3] The apoptosis of MCF7 cells induced by Staurosporine can be enhanced by the expression of functional caspase-3 via caspase-8 activation and Bid cleavage. ^[4] Staurosporine treatment at 1 μM only partially inhibits IL-3-stimulated Bcl2 phosphorylation but completely blocks PKC-mediated Bcl2 phosphorylation. ^[5] Staurosporine induces apoptosis of human foreskin fibroblasts AG-1518, depending on the lysosomal cathepsins D mediated cytochrome c release and caspase activation. ^[6] In addition to activating the classical mitochondrial apoptosis pathway, Staurosporine triggers a novel intrinsic apoptosis pathway, relying on the activation of caspase-9 in the absence of Apaf-1. ^[7]

細胞データ

Cell Lines	Assay Type	Concentration	Incubation Time	Activity Description	PMID
human colon carcinoma cell line HCT116	MmXMSpVv[3Srb36gZZN{[Xl?			NXL2emliS2:wY3XueJJifGmxbjDy[ZF2cXKnZDDmc5Ih\3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4h[2:ub36gZ4Fz[2mwb33hJINmdGxibHnu[UBJS1RzMU[sJGlEPTB;NjDuUU4>	MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTV\|N{O0OUc,OTV3M{ezOFU9N2F-
human PBMC	NEfJWplHfW6ldHnvckBie3OjeR?=		NGezSZYzPCCq	M3nSe3N2eHC{ZYPzbY9vKG:oIFnMNkBxem:mdXP0bY9vKGmwIHj1cYFvKFCETVOgZYZ1\XJiMkSgbJJ{KGK7IFXMTXNCNCCLQ{WwQVE3KG6PLh?=	M2PDSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NUi1NFQ3Lz5zOEW4OVA1PjxxYU6=
endothelial cells	MYPGeY5kfGmxbjDhd5NigQ>?			Mo\ISYZn\WO2aY\lJIRwe2ViYXfhbY5{fCCybHHzcYlvd2enbjDhZ5RqfmG2b4KgZYN1cX[rdImgd5RqdXWuYYTl[EBjgSCyaH;yZo9tKGW\|dHXyJIlvKGWwZH;0bIVtcWGuIHPlcIx{NCCHREWwJF0hPy53IN88UU4>	NVP1ZpFYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOEewPVA6PSd-OEewPVA6PTxxYU6=
Sf9 insect cells	NVLmcnI4TnWwY4Tpc44h[XO\|YYm=			MnLtTY5pcWKrdHnvckBw\iCycn;0[YlvKGurbnHz[UBEMDF8MX3pfJR2emVib3[gVGtEKGGucHjhJEYh[mW2YTmg[ZhxemW\|c3XkJIlvKFOoOTDpcpNm[3RiY3XscJMtKEmFNUCgQUAxNjB{IN88UU4>	NV;YbpNYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOUi3N\|YxPSd-OUi3N\|YxPTxxYU6=
LoVo cells	MV3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?			MoXQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiClb3zvckBk[W6lZYKgZ4VtdCCuaX7lJEhNd1[xIHPlcIx{MSC3c3nu[{BOXFRiYYPzZZktKEmFNUCgQUAxNjByMTFOwG0v	NHzybnE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUW5NVUxPSd-MUG1PVE2ODV:L3G+
umbilical vein endothelial cells	M33zSGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7			MkDURY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiC3bXLpcIlk[WxidnXpckBmdmSxdHjlcIlidCClZXzsd{ApUFWYRVPzLUB2e2mwZzDNWHQh[XO\|YYmsJGlEPTBiPTCwMlAxPCEQvF2u	NHX0eFE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUW5NVUxPSd-MUG1PVE2ODV:L3G+
ST-486 cells	NFztUG5CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=			NFvpV45CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIJ2emurdDDsfY1xcG:vYTDj[YxtKGyrbnWgLHNVNTR6NjDj[YxteylidYPpcochVVSWIHHzd4F6NCCLQ{WwJF0hOC5yMEeg{txONg>?	MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTV7MUWwOUc,OTF3OUG1NFU9N2F-
DLD-1 cells	MXfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?			NWPEflhrSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDjc4xwdiClYX7j[ZIh[2WubDDsbY5mKCiGTFStNUBk\WyuczmgeZNqdmdiTWTUJIF{e2G7LDDJR\|UxKD1iMD6wNFkh\|ryPLh?=	MoCyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF3OUG1NFUoRjFzNUmxOVA2RC:jPh?=
HEK293 cells	MkXYSpVv[3Srb36gZZN{[Xl?			M4PlTmlvcGmkaYTpc44hd2ZiUFvDMYJmfGFiSVmgcYVlcWG2ZXSgTWwuQCC{ZXzlZZNmKG[{b32gTGVMOjl\|IHPlcIx{KGK7IFXMTXNCNCCLQ{WwJF0hOC5yN{eg{txONg>?	MnnlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJ7NEGzN\|EoRjF{OUSxN\|MyRC:jPh?=
P19 cells	NH3EcmlHfW6ldHnvckBie3OjeR?=			M1TybmlvcGmkaYTpc44hd2ZiUHzheIVt\XRvZHXybZZm\CCpcn;3eIgh\mGldH;yJJJm[2WydH;yJIlvKFBzOTDj[YxteyxiSVO1NEA:KDBwMECyJO69VS5?	MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd5MUSxPUc,OTV5N{G0NVk9N2F-
P19 cells	MWDGeY5kfGmxbjDhd5NigQ>?			MVjJcohq[mm2aX;uJI9nKFCuYYTlcIV1NWSncnn2[YQh\3Kxd4ToJIZi[3SxcjDy[YNmeHSxcjDpckBROTliY3XscJMtKEmFNUCgQUAxNjByMjFOwG0v	NUHDTmVsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3O\|E1OTlpPkG1O\|cyPDF7PD;hQi=>
P19 cells	MmLnSpVv[3Srb36gZZN{[Xl?			M4S0UmlvcGmkaYTpc44hd2ZiUILveIVqdiCNaX7hd4UhSSCrbjDQNVkh[2WubIOsJGlEPTBiPTCwMlAxPCEQvF2u	NX7zb45HRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3O\|E1OTlpPkG1O\|cyPDF7PD;hQi=>
P19 cells	MV;GeY5kfGmxbjDhd5NigQ>?			MYrJcohq[mm2aX;uJI9nKEOjbHPpeY0w[2GubX;keYxqdi2mZYDlcoRmdnRicILveIVqdiCtaX7hd4UhfHmyZTDJTUBqdiCSMUmgZ4VtdHNuIFnDOVAhRSByLkCwOkDPxE1w	MmPtQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5N{G0NVkoRjF3N{exOFE6RC:jPh?=
P19 cells	NVT6VHliTnWwY4Tpc44h[XO\|YYm=			MYrJcohq[mm2aX;uJI9nKEO7Y3zpck1l\XCnbnTlcpQhc2mwYYPlJFEhcW5iUEG5JINmdGy\|LDDJR\|UxKD1iMD6wNFgh\|ryPLh?=	M3[4TFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{exOFE6Lz5zNUe3NVQyQTxxYU6=
P19 cells	MV\GeY5kfGmxbjDhd5NigQ>?			MWnJcohq[mm2aX;uJI9nKF[jc3P1cIFzKGWwZH;0bIVtcWGuIHfyc5d1cCCoYXP0c5IhemWlZYD0c5IhcW5iUEG5JINmdGy\|LDDJR\|UxKD1iMD6wNVQh\|ryPLh?=	NH;Qbpc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe3NVQyQSd-MUW3O\|E1OTl:L3G+
HEK293 cells	M{PqS2Z2dmO2aX;uJIF{e2G7			MY\Jcohq[mm2aX;uJI9nKEmOLUigdoVt\WG\|ZTDifUBJTUt{OUOgZ4VtdHNiZYjwdoV{e2mwZzDQT2Mu[mW2YUKsJGlEPTBiPTCwMlA4PyEQvF2u	MnrrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5N{G0NVkoRjF3N{exOFE6RC:jPh?=
P19 cells	MVPGeY5kfGmxbjDhd5NigQ>?			NInsPGRKdmirYnn0bY9vKG:oIFnud5VtcW5icnXj[ZB1d3Jia3nuZZNmKGmwIGCxPUBk\WyuczygTWM2OCB;IECuNkDPxE1w	NYi3U5ZURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3O\|E1OTlpPkG1O\|cyPDF7PD;hQi=>
P19 cells	MnrCSpVv[3Srb36gZZN{[Xl?			MUXJcohq[mm2aX;uJI9nKEOjc3XpckBscW6jc3WgNUBqdiCSMUmgZ4VtdHNuIFnDOVAhRSBzLkSg{txONg>?	MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd5MUSxPUc,OTV5N{G0NVk9N2F-
FL5.12-Akt1 cells	NU\yUGI6SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=			NHLUdIlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JGZNPS5zMj3Bb5QyKGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMkmg{txONg>?	NGW5UlA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkSwN\|YzPid-MU[0NFM3OjZ:L3G+
MiaPaCa-2 cells	MWLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?			NWrLfWd6SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBOcWGSYVPhMVIh[2WubIOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5\|NzFOwG0v	NHLUcYo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkSwN\|YzPid-MU[0NFM3OjZ:L3G+
FL5.12-Akt1 cells	MXrGeY5kfGmxbjDhd5NigQ>?			MoTmRYN1cX[rdImgZYdicW6\|dDDHV2s{KGmwIF\MOU4yOi2Da4SxJINmdGy\|LDDFR\|UxKD1iMD60OkDPxE1w	MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjRyM{[yOkc,OTZ2MEO2NlY9N2F-
MiaPaCa-2 cells	MWfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?			NHTOT4xCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3pZXBiS2FvMjDj[YxteyxiSVO1NEA:KDBwM{eg{txONg>?	MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjRzM{e4NEc,OTZ2MUO3PFA9N2F-
FL5.12-Akt1 cells	MnH5SpVv[3Srb36gZZN{[Xl?			MULBZ5Rqfmm2eTDh[4FqdnO2IFfTT\|MheGixc4Doc5J6dGG2aX;uJIlvKE[ONT6xNk1Cc3RzIHPlcIx{NCCHQ{WwJF0hOC52NjFOwG0v	MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjRzM{e4NEc,OTZ2MUO3PFA9N2F-
Sf21 cells	MUjGeY5kfGmxbjDhd5NigQ>?			MWTJcohq[mm2aX;uJI9nKEqDS{Og[ZhxemW\|c3XkJIlvKFOoMkGgZ4VtdHNuIFnDOVAhRSByLkCwOkDPxE1w	NEnIV\|k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{C4PFA2QSd-MUewPFgxPTl:L3G+
U937 cells	MmXxR5l1d3SxeHnjbZR6KGG\|c3H5			NXKxSVRYS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hXTl\|NzDj[YxteyxiSVO1NEA:KDJizszNMi=>	M37KUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MEi4NFY4Lz5zN{C4PFA3PzxxYU6=
Sf9 cells	NIHJeVFHfW6ldHnvckBie3OjeR?=		MVexJI1qdg>?	MlezTY5pcWKrdHnvckBw\iCqdX3hckBHgW5iZYjwdoV{e2WmIHnuJHNnQSClZXzsd{Bi\nSncjCxJI1qdiCkeTDFUGlUSSCrbjDwdoV{\W6lZTDv[kAyKHWvb3yvUEBCXFBuIFnDOVAhRSByLkCwOUDPxE1w	MmS1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd\|MUW4OVMoRjF5M{G1PFU{RC:jPh?=
Sf9 cells	MVvGeY5kfGmxbjDhd5NigQ>?		MkP1NlAhdWmwcx?=	MYjJcohq[mm2aX;uJI9nKGi3bXHuJGZ6diCneIDy[ZN{\WRiaX6gV4Y6KGOnbHzzJIFnfGW{IEKwJI1qdnNiYomgSWxKW0FiaX6gdJJme2WwY3Wgc4YhOSC3bX;sM2whSVSSLDDJR\|UxKD1iMD6wNVUh\|ryPLh?=	MojFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd\|MUW4OVMoRjF5M{G1PFU{RC:jPh?=
Sf9 cells	NHraXHRHfW6ldHnvckBie3OjeR?=		NHnTeWIyKG2rbh?=	NFvO[G1KdmirYnn0bY9vKG:oIHj1cYFvKE[7bjDlfJBz\XO\|ZXSgbY4hW2Z7IHPlcIx{KGGodHXyJFEhdWmwIHL5JGVNUVODIHnuJJBz\XOnbnPlJI9nKDFyIIXtc4wwVCCDVGCsJGlEPTBiPTCwMlA{PiEQvF2u	MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzNzNUi1N{c,OTd\|MUW4OVM9N2F-
Sf9 cells	MWrGeY5kfGmxbjDhd5NigQ>?		MXqyNEBucW6\|	NUXv[IxsUW6qaXLpeIlwdiCxZjDoeY1idiCIeX6g[ZhxemW\|c3XkJIlvKFOoOTDj[YxteyCjZoTldkAzOCCvaX7zJIJ6KEWOSWPBJIlvKHC{ZYPlcoNmKG:oIEGwJJVud2xxTDDBWHAtKEmFNUCgQUAxNjB6MzFOwG0v	MkSxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd\|MUW4OVMoRjF5M{G1PFU{RC:jPh?=
Sf9 cells	NFvzb45HfW6ldHnvckBie3OjeR?=		MV[xJI1qdg>?	MVHJcohq[mm2aX;uJI9nKGi3bXHuJGZ6diCneIDy[ZN{\WRiaX6gV4Y6KGOnbHzzJIFnfGW{IEGgcYlvKGK7IFXMTXNCKGmwIIDy[ZNmdmOnIH;mJFExOCC3bX;sM2whSVSSLDDJR\|UxKD1iMD6yO{DPxE1w	NIXpZWo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{OxOVg2Oyd-MUezNVU5PTN:L3G+
Sf9 cells	NXj0foV3TnWwY4Tpc44h[XO\|YYm=		MWqyNEBucW6\|	NYDPcWVqUW6qaXLpeIlwdiCxZjDoeY1idiCIeX6g[ZhxemW\|c3XkJIlvKFOoOTDj[YxteyCjZoTldkAzOCCvaX7zJIJ6KEWOSWPBJIlvKHC{ZYPlcoNmKG:oIEGwNEB2dW:uL1ygRXRRNCCLQ{WwJF0hOC53MTFOwG0v	MoHRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd\|MUW4OVMoRjF5M{G1PFU{RC:jPh?=
A549 cells	M3mzdWN6fG:2b4jpZ4l1gSCjc4PhfS=>		MlLKO\|IhcA>?	MUHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIH3leIhw\CxiR1m1NEA:KDBwMECyOEDPxE1w	MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR6NEe3OUc,OTh2OES3O\|U9N2F-
MDA-MB-231 cells	M4rxeGN6fG:2b4jpZ4l1gSCjc4PhfS=>		NUHMcmhmPzJiaB?=	M1OyZWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1FSS2PQj2yN\|Eh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IIP1cIZwemixZHHtbY5mKEJibXX0bI9lNCCJSUWwJF0hOC5yMEexJO69VS5?	NUfVPHZ4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0PFQ4PzVpPkG4OFg1Pzd3PD;hQi=>
HT29 cells	M3PxeGN6fG:2b4jpZ4l1gSCjc4PhfS=>		MYO3NkBp	MYLDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWFI6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIH3leIhw\CxiR1m1NEA:KDBwMEGwPUDPxE1w	NXLjXYlIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0PFQ4PzVpPkG4OFg1Pzd3PD;hQi=>
MCF7 cells	MUXGeY5kfGmxbjDhd5NigQ>?			NX;GXGZoUW6qaXLpeIlwdiCxZjDQT2EhcW5iaIXtZY4hVUOINzDj[YxteyCkeTDhdpJigS2kYYPl[EBndHWxcnXzZ4Vv[2ViYYPzZZktKEurIE2gNE4xODVizszNMi=>	MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZ3NkO2PUc,OTh4NU[zOlk9N2F-
MCF7 cells	M1XYc2Z2dmO2aX;uJIF{e2G7			NY\iNW86UW6qaXLpeIlwdiCxZjDQT2EhcW5iaIXtZY4hVUOINzDj[YxteyCkeTDhdpJigS2kYYPl[EBndHWxcnXzZ4Vv[2ViYYPzZZktKEmFNUCgQUAzKM7:TT6=	MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZ3NkO2PUc,OTh4NU[zOlk9N2F-
Sf9 cells	NUizcZRNTnWwY4Tpc44h[XO\|YYm=			M3vBXGlvcGmkaYTpc44hd2ZiaIXtZY4hW3mtIHX4dJJme3OnZDDpckBU\jliY3XscJMtKEmFNUCgQUAxNjByMzFOwG0v	NH7ybpE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEiyN\|c5PCd-MUi4NlM4QDR:L3G+
Sf9 cells	M2m5b2Z2dmO2aX;uJIF{e2G7			M1yxS2lvcGmkaYTpc44hd2ZiaIXtZY4hYkGSN{Cg[ZhxemW\|c3XkJIlvKFOoOTDj[YxteyxiSVO1NEA:KDBwMEWzJO69VS5?	NFPBcZU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEiyN\|c5PCd-MUi4NlM4QDR:L3G+
insect cells	NXPJcYhwTnWwY4Tpc44h[XO\|YYm=			MXzJcohq[mm2aX;uJI9nKGi3bXHuJJJm[2:vYnnuZY51KFCrbUGg[ZhxemW\|c3XkJIlvKGmwc3XjeEBk\WyuczDifUBJXFKILDDJR\|UxKD1iMD6wNUDPxE1w	NIL6N4w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUG3PVA4Pid-MUmxO\|kxPzZ:L3G+
HT-29 cells	MoH0RZBweHSxc3nzJIF{e2G7		MWWyJIg>	MofvTY5lfWO2aX;uJI9nKGGyb4D0c5NqeyCrbjDoeY1idiCKVD2yPUBk\WyuczDhd5Nme3OnZDDhd{BkcGGwZ3WgbY4hdWm2b3Poc45lemmjbDD0doFve22nbXLyZY5mKHCxdHXueIlidCCjZoTldkAzKGi{czDifUBLSzFic4ThbY5qdmdiYnHz[YQh\my3b4Lld4NmdmOnIHHzd4F6NCCHREWwJF0hOC5yMEK2JO69VS5?	NIC4Rmw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUSyNlIxPid-MUm0NlIzODZ:L3G+
insect Sf21 cells	NFXHOW9HfW6ldHnvckBie3OjeR?=			NUXZ[Is5UW6qaXLpeIlwdiCxZjDKRWs{KGW6cILld5Nm\CCrbjDpcpNm[3RiU3[yNUBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIHLpc5RqdnmuYYTl[EB{fWK\|dILheIUheGixc4Doc5J6dGG2aX;uMEBKSzVyIE2gNE4xODZizszNMi=>	MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTR{N{KwN{c,OTl2MkeyNFM9N2F-
Jurkat cells	NF3LNXdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=			MVHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IFrBT\|Mh\XiycnXzd4lv\yCLTEKtd5RqdXWuYYTl[EBpfW2jbjDKeZJs[XRiY3XscJMtKEmFNUCgQUAxNjB5MTFOwG0v	M1vRdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7NEK3NlA{Lz5zOUSyO\|IxOzxxYU6=
Jurkat cells	M1P3SmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7			MXfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IFrBT\|Mh\XiycnXzd4lv\yCqdX3hckBz\XO2aX7nJGp2emujdDDj[YxteyxiSVO1NEA:KDBwM{GxJO69VS5?	M1n2dFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7NEK3NlA{Lz5zOUSyO\|IxOzxxYU6=
HUE cells	M1v6XGZ2dmO2aX;uJIF{e2G7		NIf0Tow6OCCvaX7z	M2fB[2lvcGmkaYTpc44hd2ZiVlXHSnIzKGmwIFjVSUBk\WyuczDhd5Nme3OnZDDhd{BqdmirYnn0bY9vKG:oIG\FS2YucW6mdXPl[EBifXSxcHjvd5Bpd3K7bHH0bY9vKHS{ZXH0[YQh\m:{IEmwJI1qdnNiYnXmc5JmKF[HR1[gZ4hidGynbnflJIJ6KEWOSWPBMEBKSzVyIE2gNE4xPyEQvF2u	Mlf3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjBzN{CxOlMoRjJyMUewNVY{RC:jPh?=
Sf9 cells	NIPlZWpHfW6ldHnvckBie3OjeR?=		MVW2NEBucW6\|	Mon4TY5pcWKrdHnvckBw\iCqdX3hckBz\WOxbXLpcoFvfCCJU2St[pV{\WRiTlnLJIV5eHKnc4Pl[EBqdiCVZkmgZ4VtdHNiYX\0[ZIhPjBibXnud{BjgSC{YXTpc41mfHKrYzDwdo91\WmwIHvpcoF{\SCjc4PhfUwhUUN3MDC9JFIvOyEQvF2u	NG\XfY49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEW4NFU2Oid-MkC1PFA2PTJ:L3G+
Sf21 cells	M2K2fWZ2dmO2aX;uJIF{e2G7	NGPER2s{OCC3TR?=		MWLJcohq[mm2aX;uJI9nKGi3bXHuJGNJUzJia3nuZZNmKGW6cILld5Nm\CCrbjDpcpNm[3RiU3[yNUBk\WyuczD1d4lv\yCyaH;zdIhwNUOURVL0bYRmKGG\|IIP1ZpN1emG2ZTDheEA{OCC3TTygTWM2OCB;IECuNFI4KM7:TT6=	NVHvR4FURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzN\|Q4QTZpPkKxN\|M1Pzl4PD;hQi=>
Sf21 cells	M3y4WWZ2dmO2aX;uJIF{e2G7	M{LpR\|MxKHWP		MmP1TY5pcWKrdHnvckBw\iCqdX3hckBz\WOxbXLpcoFvfCCLS1utZYxxcGFiZYjwdoV{e2WmIHnuJIlve2WldDDT[lIyKGOnbHzzJJV{cW6pIIDoc5NxcG9vVXzp[4h1NUmtYYDwZWIu[WyyaHGgZZMhe3Wkc4TyZZRmKGG2IEOwJJVONCCLQ{WwJF0hOC5yM{mg{txONg>?	Mnf0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF\|M{S3PVYoRjJzM{O0O\|k3RC:jPh?=
Sf21 cells	NEPoXJdHfW6ldHnvckBie3OjeR?=	MmrSN\|AhfU1?		M3fXeGlvcGmkaYTpc44hd2ZiaIXtZY4hemWlb33ibY5idnRiSVvLMYJmfGFiZYjwdoV{e2WmIHnuJIlve2WldDDT[lIyKGOnbHzzJJV{cW6pIIDoc5NxcG9vVXzp[4h1NUmtYYDwZWIu[WyyaHGgZZMhe3Wkc4TyZZRmKGG2IEOwJJVONCCLQ{WwJF0hOC52OTFOwG0v	M{HkclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{O0O\|k3Lz5{MUOzOFc6PjxxYU6=
HeLa cells	MmHCR5l1d3SxeHnjbZR6KGG\|c3H5		NGK2c3A1QCCq	M17s[GN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODByMEC0JO69VS5?	NHTNTIs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUO4PFE6OSd-MkGzPFgyQTF:L3G+
MCF7 cells	MUHDfZRwfG:6aXPpeJkh[XO\|YYm=		NITYS3g1QCCq	M{PWWWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODVizszNMi=>	M4fldVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{i4NVkyLz5{MUO4PFE6OTxxYU6=
HT-29 cells	NUnXUHBLTnWwY4Tpc44h[XO\|YYm=		MUSyJIg>	NYG4S25KTW[oZXP0JI9vKG2rdH;jbI9v\HKrYXygcYVu[nKjbnWgdI91\W62aXHsJIlvKGi3bXHuJGhVNTJ7IHPlcIx{KGGodHXyJFIhcHK\|IIXzbY5oKEqFLUGgd5RicW6rbnegZpkh\my3b4Lld4NmdmOnIHHzd4F6NCCLQ{WwJF0hOC5yMEKg{txONg>?	MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR{OEO3OUc,OjF2MkizO\|U9N2F-
HeLa cells	MYDDfZRwfG:6aXPpeJkh[XO\|YYm=		M4PhNFQ5KGh?	Mln0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG\|c3H5MEBKSzVyIE2gNE4xODByMESg{txONg>?	MoLHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2OEi2OVUoRjJzNEi4OlU2RC:jPh?=
MCF7 cells	M4S5O2N6fG:2b4jpZ4l1gSCjc4PhfS=>		MnrwOFghcA>?	MVvDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO\|YYmsJGlEPTBiPTCwMlA2KM7:TT6=	MmLHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2OEi2OVUoRjJzNEi4OlU2RC:jPh?=
HT-29 cells	MVrGeY5kfGmxbjDhd5NigQ>?			M3nmfGlvcGmkaYTpc44hd2ZibXn0c4Npd26mcnnhcEBu\W2kcnHu[UBxd3SnboTpZYwhcW5iaIXtZY4hUFRvMkmgZ4VtdHNidYPpcochUkNzIHT5[UB{fGGrbnnu[{BjgSCobIXvdoV{[2WwY3WgdIxifGVicnXh[IVzKGG\|c3H5MEBKSzVyIE2gNE4xODJ3IN88UU4>	NV:yWlk2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG1NVMzQTNpPkKxOVE{Ojl\|PD;hQi=>
SF268 cells	M3zib2N6fG:2b4jpZ4l1gSCjc4PhfS=>		NH;3bG81QCCq	Mn3IR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV2YzPjhiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFAvODR2IN88UU4>	M2DmcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUGzNlk1Lz5{MUWxN\|I6PDxxYU6=
CHOK1 cells	MUjDfZRwfG:6aXPpeJkh[XO\|YYm=		NFPaPFg1QCCq	M3LhOWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGNJV0tzIHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEeLNUCgQUAxNjF\|IN88UU4>	NGLPd4Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWxN\|I6PCd-MkG1NVMzQTR:L3G+
H460 cells	Mo\vR5l1d3SxeHnjbZR6KGG\|c3H5		NHPBc\|M1QCCq	Ml3XR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTFQ3OCClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG\|c3H5MEBIUTVyIE2gN{43KM7:TT6=	MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTVzM{K5OEc,OjF3MUOyPVQ9N2F-
HT-29 cells	NFPIXIxEgXSxdH;4bYNqfHliYYPzZZk>		M3;pVFQ5KGh?	M3XL[mN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhVNTJ7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEeLNUCgQUA{NjZizszNMi=>	NWH3WZBFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG1NVMzQTRpPkKxOVE{Ojl2PD;hQi=>
MCF7 cells	NFXSfYFEgXSxdH;4bYNqfHliYYPzZZk>		NFqwNW01QCCq	NHr4UppEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFQ5KGi{czDifUBUWkJiYYPzZZktKEeLNUCgQUAyOSEQvF2u	NGfadmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWxN\|I6PCd-MkG1NVMzQTR:L3G+
SW1116 cells	MUTGeY5kfGmxbjDhd5NigQ>?		M3rYPFI1KGh?	MXXJcohq[mm2aX;uJI9nKHSnbH;t[ZJie2ViaX6gbJVu[W5iU2exNVE3KGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDUVmFRNVCFUj3FUGlUSSCjc4PhfUwhUUN3MDC9JFgvOzJizszNMi=>	NXXjd\|ZwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG5OlI2OjNpPkKxPVYzPTJ\|PD;hQi=>
HT-29 cells	MY\BdI9xfG:\|aYOgZZN{[Xl?		NGrLd4MzKGh?	M{jEXmlv\HWldHnvckBw\iCjcH;weI9{cXNiaX6gbJVu[W5iSGStNlkh[2WubIOgZZN{\XO\|ZXSgdoVlfWO2aX;uJI9nKG2rdH;jbI9v\HKrYXygcYVu[nKjbnWgdI91\W62aXHsJIFnfGW{IEKgbJJ{KGK7IIXzbY5oKEqFMTDzeIFqdmmwZzDifUBndHWxcnXzZ4Vv[2ViY3XscE1j[XOnZDDhd5NigSxiRVS1NEA:KDBwMECyOkDPxE1w	Ml7IQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7N{OxNFEoRjJzOUezNVAyRC:jPh?=
LoVo cells	Mn7ERY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		NGT1Noo1QCC2bzC3NkBp	NUTHNIpwSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDMc3ZwKGOnbHzzJIFnfGW{IES4JJRwKDd{IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLkCwNUDPxE1w	NG[1[2g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkG4NlkzQSd-MkKxPFI6Ojl:L3G+
ST486 cells	NXXYcI5MSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=		MkfyOFghfG9iN{KgbC=>	M3OyXWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iU2S0PFYh[2WubIOgZYZ1\XJiNEigeI8hPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMEC3JO69VS5?	M1e2dFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUiyPVI6Lz5{MkG4NlkzQTxxYU6=
DLD1 cells	NVnSeVA{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=		MnHUOFghfG9iN{KgbC=>	MXnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKESOREGgZ4VtdHNiYX\0[ZIhPDhidH:gO\|IhcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODB7IN88UU4>	M1XVfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUiyPVI6Lz5{MkG4NlkzQTxxYU6=
B16F10 cells	NFXzZphCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		NWjheFR4PDhiaB?=	MlG4RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDtc5V{\SCEMU\GNVAh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKuPFIh\|ryPLh?=	MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjVyM{O2OEc,OjJ3MEOzOlQ9N2F-
MCF7 cells	MYXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		MnTmOFghcA>?	MYHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE2FRkegZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDNwMEeg{txONg>?	NFLjNYI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkWwN\|M3PCd-MkK1NFM{PjR:L3G+
A431 cells	NEXtTZpEgXSxdH;4bYNqfHliYYPzZZk>		MYWyOEBp	Mm\NR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVQ{OSClZXzsd{Bi\nSncjCyOEBpenNidYPpcochSW6wZYjpckBX\U[LVFOvdJJweGmmaYXtJIlw\GmmZTDzeIFqdmmwZzDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjB5IN88UU4>	NF7MTmM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkW0NVA2OSd-MkK1OFExPTF:L3G+
MCF7 cells	MkH0R5l1d3SxeHnjbZR6KGG\|c3H5		MWWyOEBp	NGq4WYZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFI1KGi{czD1d4lv\yCDbn7lfIlvKF[nRlnUR{9xem:yaXTpeY0hcW:maXTlJJN1[WmwaX7nJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMUig{txONg>?	NF:4bmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkW0NVA2OSd-MkK1OFExPTF:L3G+
BJ cells	MX;DfZRwfG:6aXPpeJkh[XO\|YYm=		NXW3dGVzPzJiaB?=	NXjvXmN2S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSkpiY3XscJMh[W[2ZYKgO\|IhcHK\|IHL5JGNidGOnaX6gRW0h[XO\|YYmsJGlEPTBiPTCwMlAxOiEQvF2u	NUnpW5AxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5NlExQDFpPkKyPVIyODhzPD;hQi=>
CEM cells	MVPDfZRwfG:6aXPpeJkh[XO\|YYm=		NYnlN4dSPzJiaB?=	MVnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IFPhcINmcW5iQV2gZZN{[XluIFnDOVAhRSByLkCyN{DPxE1w	NHvjPGM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkmyNVA5OSd-MkK5NlExQDF:L3G+
MCF7 cells	NGrxSodEgXSxdH;4bYNqfHliYYPzZZk>		NVvWPIZSPzJiaB?=	NXPTWYR{S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA4OiCqcoOgZpkhS2GuY3XpckBCVSCjc4PhfUwhUUN3MDC9JFAvODZ2IN88UU4>	MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl{MUC4NUc,OjJ7MkGwPFE9N2F-
HeLa cells	MlnjR5l1d3SxeHnjbZR6KGG\|c3H5		NEHVSoY4OiCq	MljTR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC3NkBpenNiYomgR4Ft[2WrbjDBUUBie3OjeTygTWM2OCB;IECuNVc2KM7:TT6=	MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl{MUC4NUc,OjJ7MkGwPFE9N2F-
HepG2 cells	NH;aR3lHfW6ldHnvckBie3OjeR?=		NXrSWohkOjRiaB?=	Mnn2TY5pcWKrdHnvckBw\iC2ZXzvcYVz[XOnIHnuJIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDUVmFRNVCFUj3FUGlUSSCjc4PhfUwhUUN3MDC9JFQvOTRizszNMi=>	NGjHZos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{CxPFA6Pid-MkOwNVgxQTZ:L3G+
SW1116 cells	MWrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		M3TOTFQ5KGh?	MlWxRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCVV{GxNVYh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBu\XSqb3SsJGlEPTBiPTC0Mlk2KM7:TT6=	MmHBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyMUiwPVYoRjJ\|MEG4NFk3RC:jPh?=
HepG2 cells	NIDoVmVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		NEK1VYc1QCCq	MlnLRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCKZYDHNkBk\WyuczDh[pRmeiB2ODDodpMh[nliTWTUJI1mfGixZDygTWM2OCB;IE[uO\|Mh\|ryPLh?=	MoLQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyMUiwPVYoRjJ\|MEG4NFk3RC:jPh?=
BGC823 cells	MY\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		MlTEOFghcA>?	NVn0VIh2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDCS2M5OjNiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCvZYToc4QtKEmFNUCgQUA3Njh\|IN88UU4>	M1qyWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|MEG4NFk3Lz5{M{CxPFA6PjxxYU6=
HeLa cells	NX72[3RmSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=		MYC0PEBp	NEHQeG5CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjlUIEh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBu\XSqb3SsJGlEPTBiPTC5MlEzKM7:TT6=	NFTpW3A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{CxPFA6Pid-MkOwNVgxQTZ:L3G+
HCT116 cells	MW\GeY5kfGmxbjDhd5NigQ>?			MVvJcohq[mm2aX;uJI9nKFSQSVutcYVlcWG2ZXSgWGNHPC:kZYThMYNie2WrbjD0doFve2O{aYD0bY9vKGmwIHj1cYFvKEiFVEGxOkBk\WyuczDifUBj\XSjLXzhZ5RidWG\|ZTDy[ZBwenSncjDn[Y5mKGG\|c3H5MEBKSzVyIE2gNE4xOzlizszNMi=>	MnjEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{M{KwOlAoRjJ\|MkOyNFYxRC:jPh?=
HepG2 cells	M1K1SGZ2dmO2aX;uJIF{e2G7		M4\4R\|Q5KGh?	NGTMWYFKdmirYnn0bY9vKG:oIITlcI9u\XKjc3WgbY4hcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JHRTSVBvUFPSMWVNUVODLDDJR\|UxKD1iOD6zJO69VS5?	NETPWXY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{K3PVg3PCd-MkOyO\|k5PjR:L3G+
SW1116 cells	Mo\PSpVv[3Srb36gZZN{[Xl?		MkDUNlQhcA>?	MmLDTY5pcWKrdHnvckBw\iC2ZXzvcYVz[XOnIHnuJIh2dWGwIGPXNVEyPiClZXzsd{Bi\nSncjCyOEBpenNiYomgWHJCWC2SQ2KtSWxKW0FiYYPzZZktKEmFNUCgQUA1NjF6IN88UU4>	NVXFOJBnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSyPFY4PjFpPkK0Nlg3PzZzPD;hQi=>
KE-97 cells	M3LGOmN6fG:2b4jpZ4l1gSCjc4PhfS=>		NWnNVGRnPzJiaB?=	M3eyS2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGtGNTl5IHPlcIx{KGGodHXyJFczKGi{czDifUBE\WyuVHn0doUuT2yxIHz1cYlv\XOlZX70JINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC5zMzFOwG0v	M1m2e\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{K4Nlg{Lz5{NEOyPFI5OzxxYU6=
Jurkat cells	MUPDfZRwfG:6aXPpeJkh[XO\|YYm=		NELaWGo4OiCq	MUHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDKeZJs[XRiY3XscJMh[W[2ZYKgO\|IhcHK\|IHL5JGNmdGyWaYTy[U1IdG9ibIXtbY5me2OnboSgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUCgQUAxNjF2IN88UU4>	Mn2zQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR\|MkiyPFMoRjJ2M{K4Nlg{RC:jPh?=
HuH7 cells	MoHBR5l1d3SxeHnjbZR6KGG\|c3H5		MUC3NkBp	NYDjdottS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUHWKNzDj[YxteyCjZoTldkA4OiCqcoOgZpkhS2WubGTpeJJmNUeubzDseY1qdmW\|Y3XueEBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwMkOg{txONg>?	NF3qXWk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEOyPFI5Oyd-MkSzNlgzQDN:L3G+
BGC823 cells	MkfLR5l1d3SxeHnjbZR6KGG\|c3H5		Ml;kO\|IhcA>?	MlHER5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRmdEQDJ\|IHPlcIx{KGGodHXyJFczKGi{czDifUBE\WyuVHn0doUuT2yxIHz1cYlv\XOlZX70JINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwJF0hOC5\|ODFOwG0v	NYXIb5Z2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSzNlgzQDNpPkK0N\|I5Ojh\|PD;hQi=>
MCF7 cells	MlnPR5l1d3SxeHnjbZR6KGG\|c3H5		NEnzfmY4OiCq	M2\MV2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgO\|IhcHK\|IHL5JGNmdGyWaYTy[U1IdG9ibIXtbY5me2OnboSgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUCgQUAxNjV{IN88UU4>	NGfH[ZI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEOyPFI5Oyd-MkSzNlgzQDN:L3G+
NIH/3T3 cells	M3LFXGN6fG:2b4jpZ4l1gSCjc4PhfS=>		NXX6WWY{QTZiaB?=	NF;HcoxEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBPUUhxM2SzJINmdGy\|IHHmeIVzKDl4IHjyd{BjgSCVUlKgZZN{[XluIFnDOVAhRSByLkKg{txONg>?	NFXLOm89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO2NVUzOSd-MkSzOlE2OjF:L3G+
A2780 cells	NGiyWZREgXSxdH;4bYNqfHliYYPzZZk>		NFXyZWM6PiCq	MlfJR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVI4QDBiY3XscJMh[W[2ZYKgPVYhcHK\|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvOiEQvF2u	NYi3bnRHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSzOlE2OjFpPkK0N\|YyPTJzPD;hQi=>
HT-29 cells	M2Hwb2N6fG:2b4jpZ4l1gSCjc4PhfS=>		NULVTYU3QTZiaB?=	MYDDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG\|c3H5MEBKSzVyIE2gNE4zKM7:TT6=	MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN4MUWyNUc,OjR\|NkG1NlE9N2F-
8505C cells	M1joT2N6fG:2b4jpZ4l1gSCjc4PhfS=>		NFPqTIM6PiCq	MoLaR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gPFUxPUNiY3XscJMh[W[2ZYKgPVYhcHK\|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvOiEQvF2u	MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN4MUWyNUc,OjR\|NkG1NlE9N2F-
518A2 cells	NVHWV2xkS3m2b4TvfIlkcXS7IHHzd4F6		M{\rXFk3KGh?	NUiwZ\|VwS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hPTF6QUKgZ4VtdHNiYX\0[ZIhQTZiaILzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDBwMjFOwG0v	MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN4MUWyNUc,OjR\|NkG1NlE9N2F-
MCF7 cells	NHPCZlFEgXSxdH;4bYNqfHliYYPzZZk>		MlW1PVYhcA>?	Ml\DR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG\|c3H5MEBKSzVyIE2gNE41KM7:TT6=	MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN4MUWyNUc,OjR\|NkG1NlE9N2F-
A549 cells	MWjDfZRwfG:6aXPpeJkh[XO\|YYm=		NI[yWGk6PiCq	Ml\nR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG\|c3H5MEBKSzVyIE2gNE43KM7:TT6=	NFPhTXU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO2NVUzOSd-MkSzOlE2OjF:L3G+
V79 MZ cells	Mn[3SpVv[3Srb36gZZN{[Xl?			NILISXpKdmirYnn0bY9vKG:oIHj1cYFvKGGuZH;zeIVzd26nIIP5cpRp[XOnIHX4dJJme3OnZDDpckBXPzliTWqgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iCjbHTvd5Rmem:wZTDzfY51cGW\|aYOsJGlEPTBiPTCwMlAyOSEQvF2u	MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDR{MkWxPUc,OjR2MkK1NVk9N2F-
HEK293 cells	Mnm4R5l1d3SxeHnjbZR6KGG\|c3H5		M1XDd\|czKGh?	MULDfZRwfG:6aXPpeJkh[WejaX7zeEBJTUt{OUOgZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KEOnbHzUbZRmekeubzDhd5NigSxiSVO1NEA:KDBwMEW2JO69VS5?	NWfINVhIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3OlMzPjJpPkK0O\|Y{OjZ{PD;hQi=>
HeLa cells	NYDGeop6SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=		MVeyOEB1dyB2ODDo	NUH3VJFYSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEK0JJRwKDR6IHjyd{BjgSCFQ1utPEBie3OjeTygTWM2OCB;IEKuO\|Ih\|ryPLh?=	NXPTe\|l2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3PVI5OTFpPkK0O\|kzQDFzPD;hQi=>
A549 cells	MWjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		NGH6eJEzPCC2bzC0PEBp	NVnDVWs2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEK0JJRwKDR6IHjyd{BjgSCFQ1utPEBie3OjeTygTWM2OCB;IEOuNFUh\|ryPLh?=	NVP0UpRJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3PVI5OTFpPkK0O\|kzQDFzPD;hQi=>
HepG2 cells	NHnKW4JEgXSxdH;4bYNqfHliYYPzZZk>			M2LxcGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{NCCHQ{WwJF0hOiEQvF2u	NYDOepBCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWzNVY{OTdpPkK1N\|E3OzF5PD;hQi=>
Raji cells	MmDtR5l1d3SxeHnjbZR6KGG\|c3H5			MWXDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDSZYpqKGOnbHzzMEBGSzVyIE2gNkDPxE1w	NVnXWW5SRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWzNVY{OTdpPkK1N\|E3OzF5PD;hQi=>
BJ cells	M1vFWWN6fG:2b4jpZ4l1gSCjc4PhfS=>			MXnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDCTkBk\WyuczygSWM2OCB;IEKg{txONg>?	M1i0RlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3M{G2N\|E4Lz5{NUOxOlMyPzxxYU6=
HEK293 cells	NF7DUIhEgXSxdH;4bYNqfHliYYPzZZk>			NEn3VGZEgXSxdH;4bYNqfHliYXfhbY5{fCCKRVuyPVMh[2WubIOsJGVEPTBiPTCyJO69VS5?	NF\M[G09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUOxOlMyPyd-MkWzNVY{OTd:L3G+
A549 cells	NGiwPJFEgXSxdH;4bYNqfHliYYPzZZk>		NH;VfZc1QCCq	NEjlWnZEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjB{IN88UU4>	NGf0eng9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUiyOVk{PCd-MkW4NlU6OzR:L3G+
HeLa cells	MXrDfZRwfG:6aXPpeJkh[XO\|YYm=		NVPTTm5NPDhiaB?=	M{D4PWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODJ3IN88UU4>	NHL5NIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUiyOVk{PCd-MkW4NlU6OzR:L3G+
PC3 cells	MXPDfZRwfG:6aXPpeJkh[XO\|YYm=		MXu0PEBp	MnftR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO\|YYmsJGlEPTBiPTCwMlA{OSEQvF2u	NWPQO3lyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4NlU6OzRpPkK1PFI2QTN2PD;hQi=>
MGC-803 cells	NIrXSnBHfW6ldHnvckBie3OjeR?=		MVWyOEBp	MW\Jcohq[mm2aX;uJI9nKHSnbH;t[ZJie2ViaX6gbJVu[W5iTVfDMVgxOyClZXzsd{Bi\nSncjCyOEBpenNiYomgWHJCWC2SQ2KtSWxKW0FiYYPzZZktKEmFNUCgQUA5Njl5IN88UU4>	MmWxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ7MEC2OVYoRjJ4OUCwOlU3RC:jPh?=
Sf9 insect cells	MlWySpVv[3Srb36gZZN{[Xl?		M1PNWlExKG2rboO=	NIPMT2lKdmirYnn0bY9vKG:oIF6teIVzdWmwYXygS3NVKHSjZ3fl[EBz\WOxbXLpcoFvfCCodXzsMYxmdme2aDDoeY1idiCFSFuxJIV5eHKnc4Pl[EBqdiCkYXP1cI93cXK3czDT[lkhcW6\|ZXP0JINmdGy\|IHHmeIVzKDFyIH3pcpMh[nlibIXtbY5me2OnboSgRWRRNUeubzDhd5NigSxiSVO1NEA:KDBwMECxNkDPxE1w	MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzB6OUKxNUc,OjdyOEmyNVE9N2F-
Sf21 cells	MmPMSpVv[3Srb36gZZN{[Xl?		MXO2NEBucW6\|	NEXRfoFKdmirYnn0bY9vKG:oIHj1cYFvKHKnY3;tZolv[W62IFrBT\|Ih\XiycnXzd4VlKGmwIGPmNlEh[2WubIOgZZN{\XO\|ZXSgZZMhemWmdXP0bY9vKGmwIGXsbYdpfC2FQVfBS2FKTVSGS1XZXXRXU0RicHjvd5Bpd3K7bHH0bY9vKHC{ZT3pcoN2[mG2ZXSgZoVnd3KnIIP1ZpN1emG2ZTDh[IRqfGmxbjDhcoQhdWWjc4Xy[YQh[W[2ZYKgOlAhdWmwczDifUBNSU6FRTDk[ZRm[3Srb36gcYV1cG:mLDDJR\|UxKD1iMD6wNFIh\|ryPLh?=	MlO4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdzM{ezOVkoRjJ5MUO3N\|U6RC:jPh?=
Neuro2a cells	NHLBWopEgXSxdH;4bYNqfHliYYPzZZk>		NWTzUZlSPzJiaB?=	MmTRR5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgUoV2em9{YTDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKH[rYXLpcIl1gSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5yMUGzJO69VS5?	MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDF3MkSyO{c,OjhzNUK0Nlc9N2F-
MDA-MB-231 cells	M{LFRmZ2dmO2aX;uJIF{e2G7		MofmNVYhcA>?	NVXZ[41SUW6qaXLpeIlwdiCxZjDy[ZRqdm:kbHHzeI9u[SCycn;0[YlvKHCqb4PwbI9zgWyjdHnvckBqdiCqdX3hckBOTEFvTVKtNlMyKGOnbHzzJIFnfGW{IEG2JIhzeyCkeTDIc4VkcHO2IEOzN\|QzKHO2YXnubY5oKGKjc3XkJIZtfW:{ZYPj[Y5k\SCjc4PhfUwhUUN3MDC9JFAvODZ4IN88UU4>	MmToQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh2M{GzOFIoRjJ6NEOxN\|QzRC:jPh?=
Sf9 insect cells	MkHHSpVv[3Srb36gZZN{[Xl?		MXSyNEBucW6\|	MXHJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKE5vdHXycYlv[WyueTDHV3QufGGpZ3XkJGVITlJiTEi1PHIwXDd7MF2vR\|c6P1NidILpdIxmKG23dHHueEBmgHC{ZYPz[YQhcW5iYnHjeYxwfmm{dYOgbY4hW2Z7IHnud4VkfCClZXzsd{BxemWrbnP1ZoF1\WRiZn;yJFIxKG2rboOg[o9tdG:5ZXSgZpkh[WSmaYTpc44hd2ZiW{OzVH0uSVSSIH3lZZN2emWmIHHmeIVzKDJiaILzJIJ6KG[rbITldk1jcW6maX7nJI1mfGixZDygTWM2OCB;IECuNFAxOjlizszNMi=>	MmPEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh2OEKxOVEoRjJ6NEiyNVUyRC:jPh?=
HEK293 cells	NFnKUpdEgXSxdH;4bYNqfHliYYPzZZk>		NFv0XpQ4OiCq	NE\veVREgXSxdH;4bYNqfHliYXfhbY5{fCCKRVuyPVMh[2WubIOgZZN{\XO\|ZXSgZZMh\GWlcnXhd4UhcW5iY3XscEB3cWGkaXzpeJkh[W[2ZYKgO\|IhcHK\|IHL5JGNmdGyWaYTldkBIdG9ibIXtbY5me2OnboSgZZN{[XluIFPDOVAhRSByLkCwN\|U1KM7:TT6=	MnXlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4MkS3NFEoRjJ6NkK0O\|AyRC:jPh?=
BT549 cells	MUfDfZRwfG:6aXPpeJkh[XO\|YYm=		MVeyOEBp	NYC0[IpsS3m2b4TvfIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gRnQ2PDliY3XscJMhcW6ldXLheIVlKG[xcjCyOEBpenNiYomgUXRVKGG\|c3H5MEBKSzVyIE2gNE4xQCEQvF2u	MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDdyNUSzNkc,Ojh5MEW0N\|I9N2F-
MDA-MB-468 cells	MVTDfZRwfG:6aXPpeJkh[XO\|YYm=		NHTGTHczPCCq	Mn20R5l1d3SxeHnjJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTVTBMW1DNTR4ODDj[YxteyCrbnP1ZoF1\WRiZn;yJFI1KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjF3IN88UU4>	M3:zWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6N{C1OFMzLz5{OEewOVQ{OjxxYU6=
MDA-MB-231 cells	MVjDfZRwfG:6aXPpeJkh[XO\|YYm=		MnTjNlQhcA>?	M{\ERWN6fG:2b4jpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiaX7jeYJifGWmIH\vdkAzPCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5{NDFOwG0v	MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDdyNUSzNkc,Ojh5MEW0N\|I9N2F-
Vero cells	NY\CNGtHS3m2b4TvfIlkcXS7IHHzd4F6		NX;4dXpoOiCmYYnz	MYrDfZRwfG:6aXPpeJkh[WejaX7zeEBC\nKrY3HuJIdz\WWwIH3vcotmgSCYZYLvJINmdGy\|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBi\nSncjCyJIRigXNiYomgZ4VtdC22aYTldk1odG9ibIXtbY5me2OnboSgZZN{[XluIGTDOVAhRSByLkCwNlQh\|ryPLh?=	MnjUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5NkO2OFUoRjJ6N{[zOlQ2RC:jPh?=
L929 cells	M{SzNWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7		Mlu5OUBl[Xm\|	M3zEbmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgcY92e2ViTEmyPUBk\WyuczDh[pRmeiB3IHThfZMh[nliV2PUMVEh[XO\|YYmsJGlEPTBiPTCwMlIh\|ryPLh?=	NWXBdYJnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5OVY6OTVpPkK4PVU3QTF3PD;hQi=>
KB-3-1 cells	NE\TNYlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		MkDrOUBl[Xm\|	NET4TWhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFvCMVMuOSClZXzsd{Bi\nSncjC1JIRigXNiYomgW3NVNTFiYYPzZZktKEmFNUCgQUAxNjJizszNMi=>	NXjpfJlCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5OVY6OTVpPkK4PVU3QTF3PD;hQi=>
MCF7 cells	MWjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		MYm1JIRigXN?	MknNRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCPQ1[3JINmdGy\|IHHmeIVzKDViZHH5d{BjgSCZU2StNUBie3OjeTygTWM2OCB;IEGuPEDPxE1w	NWXvPIhFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5OVY6OTVpPkK4PVU3QTF3PD;hQi=>
FS4-LTM cells	NHr2eoJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		MVSyOEBp	MWrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE[VND3MWG0h[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IGfTWE0yKGG\|c3H5MEBKSzVyIE2gNk45KM7:TT6=	NGfUOII9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEm1OlkyPSd-Mki5OVY6OTV:L3G+
Vero cells	NUXL[WlCS3m2b4TvfIlkcXS7IHHzd4F6		MkOxNkBl[Xm\|	M4qzVmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEGocnnjZY4h\3KnZX6gcY9vc2W7IG\ldo8h[2WubIOgZYZ1\XJiMjDkZZl{KGK7IFPlcIxVcXSncj3HcI8hdHWvaX7ld4NmdnRiY3XscEB3cWGkaXzpeJkh[XO\|YYmsJGlEPTBiPTCwMlAxOjRizszNMi=>	NHP1[2w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEm5N\|ExPid-Mki5PVMyODZ:L3G+
HepG2 cells	MlTFR5l1d3SxeHnjbZR6KGG\|c3H5	MoLCNVAxKHWP	MnX0N{Bl[Xm\|	M2\vOGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGG2IEGwNEB2VSCjZoTldkA{KGSjeYOgZpkhS2WubGTpeIVzNUeubzDseY1qdmW\|Y3XueEBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwMEG4JO69VS5?	NYLGVZNzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki5PVMyODZpPkK4PVk{OTB4PD;hQi=>
NIH/3T3 cells	MVfDfZRwfG:6aXPpeJkh[XO\|YYm=		NWK3OlNxQTZiaB?=	MXrDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W\|ZTDOTWgwO1R\|IHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEWFNUCgQUAxNjByODFOwG0v	M17mTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUm3O\|MxLz5{OUG5O\|c{ODxxYU6=
518A2 cells	NFvmWG5EgXSxdH;4bYNqfHliYYPzZZk>		Mn3QPVYhcA>?	NFL3[ItEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckA2OTiDMjDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCHQ{WwJF0hOC5yMzFOwG0v	NGm0fm89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUG5O\|c{OCd-MkmxPVc4OzB:L3G+
A549 cells	M{e0VmN6fG:2b4jpZ4l1gSCjc4PhfS=>		NGfOW4U6PiCq	Mn3nR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG\|c3H5MEBGSzVyIE2gNE4xPCEQvF2u	NUCyXVdIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxPVc4OzBpPkK5NVk4PzNyPD;hQi=>
MCF7 cells	NXXlcncyS3m2b4TvfIlkcXS7IHHzd4F6		M4jsVlk3KGh?	MYnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEm2JIhzeyCkeTDTVmIh[XO\|YYmsJGVEPTBiPTCwMlEh\|ryPLh?=	NX;NV2U6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmxPVc4OzBpPkK5NVk4PzNyPD;hQi=>
A2780 cells	M3HXVmN6fG:2b4jpZ4l1gSCjc4PhfS=>		NFKzXoI6PiCq	MlrZR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVI4QDBiY3XscJMh[W[2ZYKgPVYhcHK\|IHL5JHNTSiCjc4PhfUwhTUN3MDC9JFAvOTJizszNMi=>	M1G4VVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUm3O\|MxLz5{OUG5O\|c{ODxxYU6=
HT-29 cells	NXWxVYMxS3m2b4TvfIlkcXS7IHHzd4F6		NWjxNJNPQTZiaB?=	NEPCcoFEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXC1{OTDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCHQ{WwJF0hOC5zNTFOwG0v	M1\we\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7MUm3O\|MxLz5{OUG5O\|c{ODxxYU6=
PC3 cells	NIC2[pdEgXSxdH;4bYNqfHliYYPzZZk>			NIXmRm5EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhUUN3MDC9JFAvODF5IN88UU4>	NY[yUG0zRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmzPFkyOjJpPkK5N\|g6OTJ{PD;hQi=>
HCT116 cells	M{K2XmN6fG:2b4jpZ4l1gSCjc4PhfS=>			NH;MWXNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYomgd5Vt\m:{aH;kZY1qdmViQjDhd5NigSxiSVO1NEA:KDBwMEW1JO69VS5?	M3TXUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7M{i5NVIzLz5{OUO4PVEzOjxxYU6=
insect cells	NEjDSoJHfW6ldHnvckBie3OjeR?=		M1vUTVMxKG2rboO=	NWnB[IRUUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDQSGdHWmKndHGg[ZhxemW\|c3XkJIlvKGmwc3XjeEBk\WyuczD1d4lv\yCXbHnnbJQuWG:ueTDHRXRcTUG\KEG6NVoyMV2wIHHzJJN2[nO2cnH0[UBi\nSncjCzNEBucW6\|IHL5JGxCVkOHIH3leIhw\CxiSVO1NEA:KDBwMECwO\|Yh\|ryPLh?=	M4Dk[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
Sf9 insect cells	NULQOYhnTnWwY4Tpc44h[XO\|YYm=		M1m0VVYxKG2rboO=	NVH2boFzUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDLSHIh\XiycnXzd4VlKGmwIGPmPUBqdnOnY4SgZ4VtdHNidYPpcochXWyrZ3j0MWNCT0GJQVnFWGRMTVm\VG\LSEBieyC\|dXLzeJJifGViYX\0[ZIhPjBibXnud{BjgSCOQV7DSUBu\XSqb3SsJGlEPTBiPTCwMlAxOjFizszNMi=>	M1\o[\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
insect cells	NYXjRnh5TnWwY4Tpc44h[XO\|YYm=		NX;uU2R3OTBibXnudy=>	NX7wNJp6UW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDTdoMh\XiycnXzd4VlKGmwIHnud4VkfCClZXzsd{B2e2mwZzDVcIlocHRvUH;sfUBISVSdRVHZLFE7OTpzKW3uJIF{KHO3YoP0doF1\SCjZoTldkAyOCCvaX7zJIJ6KEyDTlPFJI1mfGixZDygTWM2OCB;IECuNFA2KM7:TT6=	NXv4fW9PRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1OFk5OzZpPkK5OVQ6QDN4PD;hQi=>
insect cells	M1TEfWZ2dmO2aX;uJIF{e2G7		NIjBPYUyPSCvaX7z	NUnNdnVNUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDDSGsyN0O7Y3zpckBDKGW6cILld5Nm\CCrbjDpcpNm[3RiY3XscJMhfXOrbnegWYxq\2i2LVPGSmtPUV[WUGLUVHBRW1GJSz3hcYll\SCjczDzeYJ{fHKjdHWgZYZ1\XJiMUWgcYlveyCkeTDMRW5ETSCvZYToc4QtKEmFNUCgQUAxNjB{NTFOwG0v	M4n4cVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
insect cells	MV7GeY5kfGmxbjDhd5NigQ>?		NVy2WG92OTVibXnudy=>	MlfkTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCFRFuxM2N6[2yrbjDCJIV5eHKnc4Pl[EBqdiCrboPlZ5Qh[2WubIOgeZNqdmdiVXzp[4h1NUOIRlvOTXZVWFKWUGDQV3FIUy2jbXnk[UBieyC\|dXLzeJJifGViYX\0[ZIhOTVibXnud{BjgSCOQV7DSUBu\XSqb3SsJGlEPTBiPTCwMlAzPSEQvF2u	NHzkd2o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUW0PVg{Pid-Mkm1OFk5OzZ:L3G+
Sf9 insect cells	Mlq0SpVv[3Srb36gZZN{[Xl?		NHuwTmEyPSCvaX7z	MYrJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKE[udEGg[ZhxemW\|c3XkJIlvKFOoOTDpcpNm[3RiY3XscJMhfXOrbnegWYxq\2i2LWTLJJBmeHSrZHWgZZMhe3Wkc4TyZZRmKGGodHXyJFE2KG2rboOgZpkhVEGQQ1WgcYV1cG:mLDDJR\|UxKD1iMD6wN\|Uh\|ryPLh?=	NYrQNWtwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1OFk5OzZpPkK5OVQ6QDN4PD;hQi=>
Sf21 insect cells	M2PMdmZ2dmO2aX;uJIF{e2G7		M{PiOFE2KG2rboO=	M1LQUWlvcGmkaYTpc44hd2ZicnXjc41jcW6jboSgbJVu[W5iQYXyc5JiNUFiZYjwdoV{e2WmIHnuJHNnOjFiaX7z[YN1KGOnbHzzJJV{cW6pIGXsbYdpfC2UUmLTUGxGKGG\|IIP1ZpN1emG2ZTDh[pRmeiBzNTDtbY5{KGK7IFzBUmNGKG2ndHjv[EwhUUN3MDC9JFAvODN7IN88UU4>	M4LkVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
insect cells	M2TEd2Z2dmO2aX;uJIF{e2G7		NWL2XXU2PjBibXnudy=>	NXHxcJBVUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDBT3QyKGW6cILld5Nm\CCrbjDpcpNm[3RiY3XscJMhfXOrbnegR3JGSnSrZHWgZZMhe3Wkc4TyZZRmKGGodHXyJFYxKG2rboOgZpkhVEGQQ1WgcYV1cG:mLDDJR\|UxKD1iMD6wOVYh\|ryPLh?=	MoTVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3NEm4N\|YoRjJ7NUS5PFM3RC:jPh?=
Sf9 insect cells	NX7FRpBbTnWwY4Tpc44h[XO\|YYm=		NFO5OW43OCCvaX7z	NVvXbYFFUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDGRWsh\XiycnXzd4VlKGmwIGPmPUBqdnOnY4SgZ4VtdHNidYPpcochXWyrZ3j0MXRMKHCncITp[IUh[XNic4Xid5Rz[XSnIHHmeIVzKDZyIH3pcpMh[nliTFHOR2UhdWW2aH;kMEBKSzVyIE2gNE4xPjJizszNMi=>	NUPhTWNbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1OFk5OzZpPkK5OVQ6QDN4PD;hQi=>
insect cells	MnzPSpVv[3Srb36gZZN{[Xl?		MV22NEBucW6\|	MYDJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKEGETDDlfJBz\XO\|ZXSgbY4hcW6\|ZXP0JINmdGy\|IIXzbY5oKFWuaXfoeE1VUyCyZYD0bYRmKGG\|IIP1ZpN1emG2ZTDh[pRmeiB4MDDtbY5{KGK7IFzBUmNGKG2ndHjv[EwhUUN3MDC9JFAvOjlizszNMi=>	NUnmXmRmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1OFk5OzZpPkK5OVQ6QDN4PD;hQi=>
insect cells	MYLGeY5kfGmxbjDhd5NigQ>?		NHPheok3OCCvaX7z	NUXLZ2tNUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDjMW1GXCCneIDy[ZN{\WRiaX6gbY5{\WO2IHPlcIx{KHW\|aX7nJHVtcWeqdD3DRWdCT0GLRWTET2V[YVSYS1SgZZMhe3Wkc4TyZZRmKGGodHXyJFYxKG2rboOgZpkhVEGQQ1WgcYV1cG:mLDDJR\|UxKD1iMD6zNUDPxE1w	MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTV2OUizOkc,Ojl3NEm4N\|Y9N2F-
PC3 cells	MVnDfZRwfG:6aXPpeJkh[XO\|YYm=		MYG3NkBp	MoS0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDTVmIh[XO\|YYmsJGlEPTBiPTCwMlA{QSEQvF2u	M1\YclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUW4NVE6Lz5{OUW1PFEyQTxxYU6=
Sf9 cells	M3;2U2Z2dmO2aX;uJIF{e2G7		NX6zblN{PDVibXnudy=>	NV;Hd4llUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDDMZRmem2rbnHsJGhqey22YXfn[YQwVi22ZYLtbY5idCCJU2SteIFo\2WmIFXHSnIhMDZ4ODD0c{AyOjFyIILld4llfWW\|KTDlfJBz\XO\|ZXSgbY4h[mGldXzveolzfXNiaX7m[YN1\WRiU3[5JINmdGy\|IIXzbY5oKFCxbImtLGdtfSxiVInyLUBieyC\|dXLzeJJifGVibXXhd5Vz\WRiYX\0[ZIhPDVibXnueZRmeyCkeTDLbY5ie2VvR3zvJIx2dWmwZYPj[Y51KGG\|c3H5MEBKSzVyIE2gNE4xPDdizszNMi=>	M1OwNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7OUCyO\|E6Lz5{OUmwNlcyQTxxYU6=
Sf9 cells	MVnGeY5kfGmxbjDhd5NigQ>?		NFfpZWU1PSCvaX7z	NFjsfmxKdmirYnn0bY9vKG:oIILlZ49u[mmwYX70JIh2dWGwIF6teIVzdWmwYXygS3NVNXSjZ3fl[EBJTVJ{IDi2O\|khfG9iMUK1OUBz\XOrZIXld{kh\XiycnXzd4VlKGmwIHLhZ5Vtd3[rcoXzJIlv\mWldHXkJHNnQSClZXzsd{B2e2mwZzDQc4x6NSiJbIWsJHR6eiliYYOgd5Vje3S{YYTlJI1m[XO3cnXkJIFnfGW{IES1JI1qdnW2ZYOgZpkhU2mwYYPlMWdtdyCudX3pcoV{[2WwdDDhd5NigSxiSVO1NEA:KDBwME[wPEDPxE1w	MnSzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl7MEK3NVkoRjJ7OUCyO\|E6RC:jPh?=
HT-29 cells	MkXKSpVv[3Srb36gZZN{[Xl?		MUOzJIg>	MYrJcohq[mm2aX;uJI9nKG2rdH;jbI9v\HKrYXygcYVu[nKjbnWgdI91\W62aXHsJIlvKGi3bXHuJGhVNTJ7IHPlcIx{KGGodHXyJFMhcHK\|IHL5JGpENTFic4ThbY5qdmdiYnHz[YQh\my3b4Lld4NmdmOnIHHzd4F6NCCLQ{WwJF0hOC5yMjFOwG0v	NIHvfXQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9\|MEC1O\|E2PSd-M{CwOVcyPTV:L3G+
Sf9 cells	M{TVdGZ2dmO2aX;uJIF{e2G7			MVHJcohq[mm2aX;uJI9nKE5vdHXycYlv[WxiRlzBS{11[WepZXSgbJVu[W5iZoXscE1t\W6pdHigR2RMOTJiKEGgeI8hOTR7MDDy[ZNq\HWnczmvUk11\XKvaX7hcEBJcXNvdHHn[4VlKEO7Y1ugLFEhfG9iNUiwJJJme2mmdXXzLUBmgHC{ZYPz[YQhcW5iU3[5JINmdGy\|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiCDVGCt[IVx\W6mZX70JHVNcWeqdD20SU1DWDFiKGTodlM4N1SqckS2LUB{fWK\|dILheIUheGWydHnk[UBxcG:\|cHjvdplt[XSrb36gdJItKEmFNUCgQUAxNjB3MzFOwG0v	NVP2W5BtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CwOlc{PThpPkOwNFY4OzV6PD;hQi=>
Sf9 cells	M2nteGZ2dmO2aX;uJIF{e2G7			M3jLZWlvcGmkaYTpc44hd2ZiTj30[ZJucW6jbDDGUGFINXSjZ3fl[EBpfW2jbjDmeYxtNWynbnf0bEBETEtzMjCoNUB1dyBzNEmwJJJme2mmdXXzLU9PNXSncn3pcoFtKEircz30ZYdo\WRiQ4njT{ApOSC2bzC1PFAhemW\|aXT1[ZMqKGW6cILld5Nm\CCrbjDT[lkh[2WubIOgZZN{\XO\|ZXSgZZMhemWmdXP0bY9vKGmwIFHUVE1l\XCnbnTlcpQhXUyrZ3j0MVRGNUKSMTCoWIhzOzdxVHjyOFYqKHO3YoP0doF1\SCyZYD0bYRmKHCqb4PwbI9zgWyjdHnvckBxeixiSVO1NEA:KDBwMEWzJO69VS5?	NF[yUms9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9\|MEC2O\|M2QCd-M{CwOlc{PTh:L3G+
Sf9 cells	M4nhV2Z2dmO2aX;uJIF{e2G7			MkHPTY5pcWKrdHnvckBw\iCQLYTldo1qdmGuIF\MRWcufGGpZ3XkJIh2dWGwIH\1cIwudGWwZ4ToJGNFUzF\|IDixJJRwKDF3MUKgdoV{cWS3ZYOpM24ufGW{bXnuZYwhUGm\|LYTh[4dm\CCFeXPLJEgyKHSxIEW4NEBz\XOrZIXld{kh\XiycnXzd4VlKGmwIGPmPUBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iQWTQMYRmeGWwZHXueEBWVGmpaIStOGUuSlBzIDjUbJI{Py:WaIK0Okkhe3Wkc4TyZZRmKHCncITp[IUheGixc4Doc5J6dGG2aX;uJJBzNCCLQ{WwJF0hOC5yNUeg{txONg>?	MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODB4N{O1PEc,OzByNkezOVg9N2F-
Sf9 cells	MkTxSpVv[3Srb36gZZN{[Xl?			M3PldGlvcGmkaYTpc44hd2ZiTj30[ZJucW6jbDDGUGFINXSjZ3fl[EBpfW2jbjDmeYxtNWynbnf0bEBETEtzMzCoNUB1dyBzNUGyJJJme2mmdXXzLU9PNXSncn3pcoFtKEircz30ZYdo\WRiQ4njT{ApOSC2bzC1PFAhemW\|aXT1[ZMqKGW6cILld5Nm\CCrbjDT[lkh[2WubIOgZZN{\XO\|ZXSgZZMhemWmdXP0bY9vKGmwIFHUVE1l\XCnbnTlcpQhXUyrZ3j0MVRGNUKSMTCoWIhzOzdxVHjyOFYqKHO3YoP0doF1\SCyZYD0bYRmKHCqb4PwbI9zgWyjdHnvckBxeixiSVO1NEA:KDBwMEW3JO69VS5?	M2D4VlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyME[3N\|U5Lz5\|MEC2O\|M2QDxxYU6=
HCT116 cells	NXvUc\|NCS3m2b4TvfIlkcXS7IHHzd4F6		M37sNFQ5KGh?	M4DMSmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDFzNjDj[YxteyCjc4Pld5Nm\CCjczDk[YNz\WG\|ZTDpckBk\WyuII\pZYJqdGm2eTDh[pRmeiB2ODDodpMh[nliTWTUJIF{e2G7LDDJR\|UxKD1iMD6wN{DPxE1w	M3Hxc\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMUC2NlkyLz5\|MEGwOlI6OTxxYU6=
Huh7.5 cells	M1nUOGN6fG:2b4jpZ4l1gSCjc4PhfS=>		NVfhUmlCPDhiaB?=	MWrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIeYg4NjViY3XscJMh[XO\|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZ4VtdCC4aXHibYxqfHliYX\0[ZIhPDhiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwNjFOwG0v	NYLpNYZERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CxNFYzQTFpPkOwNVA3OjlzPD;hQi=>
K562 cells	MX3DfZRwfG:6aXPpeJkh[XO\|YYm=		MV60PEBp	MlfiR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gT\|U3OiClZXzsd{Bie3Onc4Pl[EBieyCmZXPy[YF{\SCrbjDj[YxtKH[rYXLpcIl1gSCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOS55IN88UU4>	MlXoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzBzME[yPVEoRjNyMUC2NlkyRC:jPh?=
LO2 cells	NIrEWYJEgXSxdH;4bYNqfHliYYPzZZk>		M4rw[VQ5KGh?	MnfYR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUG8zKGOnbHzzJIF{e2W\|c3XkJIF{KGSnY4LlZZNmKGmwIHPlcIwhfmmjYnnsbZR6KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUA6NjVizszNMi=>	NVqzOYg{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CxNFYzQTFpPkOwNVA3OjlzPD;hQi=>

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アッセイ

Methods	Test Index	PMID
Western blot	FAK / RIP; PubMed: 15121855 Mol Cell Biol Western blot (WB) analysis of BT-20 and BT-474 lysates treated with staurosporine (200 nM). Control cells were treated with dimethyl sulfoxide for 18 h. p-Akt / Akt / PARP /Cleaved PARP; PubMed: 24174874 Int J Nanomedicine Western blot analysis for Akt, P-Akt, and cleaved poly(ADP-ribose) polymerase. U87 cells were incubated with 200 nM, 10 nM, and 0.1 nM of staurosporine encapsulated in liposomes and staurosporine for 32 hours. Ambra1; PubMed: 24587252 PLoS One SW620 cells treated with various doses of staurosporine for 6 h. Ambra1 levels were measured by Western blot.	15121855 24174874 24587252
Growth inhibition assay	Cell viability; PubMed: 25215174 Oxid Med Cell Longev Staurosporine reduces cerebellar astrocytes viability. (a) Cerebellar astrocytes were treated with staurosporine 0.1 μM, 0.25 μM, and 0.5 μM for 24 h and the cell viability was measured by MTT transformation. (b) Cerebellar astrocytes were treated with staurosporine 0.5 μM for 6, 12, and 24 h and the cell viability was measured by MTT transformation. Data are presented as mean ± SEM of four independent experiments. ∗ is significantly different from control (P < 0.05).	25215174
Immunofluorescence	Phalloidin / Type II collagen; PubMed: 22684244 Exp Mol Med Cell were cultured in the absence (a-f) or presence of staurosporine (STSN, 5 × 10-9M) or cytochalasin D (CD, 1 µg/ml) for 1 (upper panel) or 2 (lower panel) days at low density and stained for F-actin (Phalloidin) and type II collagen (Type II). STSN: Staurosporine. Tubulin / Actin; PubMed: 25215174 Oxid Med Cell Longev Morphological changes of astrocytes induced by St are evidenced by the rearrangement of cytoskeletal proteins. Astrocytes were treated with St (0.5 μM) for 12 hours and then were labelled with rhodamine-phalloidin or immunostained for tubulin. Representative images of phase contrast, rhodamine-phalloidin, and tubulin are shown in control and St treated astrocytes. Scale bar represents 50 μm. FAK 4.47; PubMed: 15121855 Mol Cell Biol BT-20 or BT-474 cell culture were plated on six-well plates and were treated with staurosporine (200 nM) after 24 h. After 6 h of treatment, cells were immunostained with anti-FAK 4.47 antibody (white arrowheads mark some focal adhesions). cleaved-caspase 3; PubMed: 19840952 Cardiovasc Res Representative images (×1000 magnification) showing vehicle treated (C) and staurosporine treated (D) cells stained with anti-cleaved caspase 3 antibody and DAPI. Annexin; PubMed: 15140398 Neoplasia Induction of apoptosis with staurosporine resulting in activation of the ICE-NIRF probe. Gli36 cells were treated with 50 µM staurosporine for 24 hours (A-C) or with the same percentage of DMSO (0.01%) to which experimental wells were exposed (D-488nm laser, E-633nm laser and F-bright field). To examine the role of caspase-1 in staurosporine-induced apoptosis and probe activation, cells were coincubated in caspase-1 inhibitor (10 µM) and staurosporine (G-I). Staurosporine induces apoptosis, indicated by the positive annexin staining viewed with the 488-nm laser (A), which colocalized with activated probe viewed with the 633-nm laser (B). Coincubation of the caspase-1 inhibitor with staurosporine did not completely block apoptosis, indicated by the relatively higher number of apoptotic cells stained with annexin (G), as those that activated the probe (H). Magnification, x 40; scale bar, 50 µM. Pyk2; PubMed: 19880522 J Biol Chem Pyk2 translocates to the nucleus upon staurosporine addition to ID8 cells. Confocal immunofluorescent analysis of endogenous Pyk2 upon DMSO (control) or 1 μm staurosporine addition for 2 h. The scale bar is 10 μm.	22684244 25215174 15121855 19840952 15140398 19880522

体内試験

In the gerbil and rat ischemia models, Staurosporine pretreatment (0.1-10 ng) before ischemia prevents neuronal damage in a dose-dependent manner, suggesting the involvement of PKC in CAl pyramidal cell death after ischemia. ^[8]

お薦めの試験操作（参考用のみ）

キナーゼ試験： ^[1]	- 合併 Enzyme assay and binding assay: Protein kinase C is assayed in a reaction mixture (0.25 mL) containing 5 μmol of Tris/HCl, pH 7.5, 2.5 μmol of magnesium acetate, 50 μg of histone II S, 20 μg of phosphatidylserine, 0.88 μg of diolein, 125 nmol of CaCl₂, 1.25 nmol of [γ-³²]ATP (5-10 × 10⁴ cpm/nmol) and 5 μg of partially purified enzyme. The binding of [³H]PDBu to protein kinase C is determined: Reaction mixture (200 μL contained 4 μmo1 of Tris/malate, pH 6.8, 20 μmol of KCl, 30 nmol of CaC1₂, 20 μg of phosphatidylserine, 5 μg of partially purified protein kinase C, 0.5% (final concentration) of DMSO,10 pmol of [³H]PDBu (l-3 × 10⁴ cpm/pmol) and 10 μL of various amounts of Staurosporine.
細胞試験： ^[3]	- 合併細胞株： PC12 濃度： Dissolved in DMSO, final concentration 1 μM 反応時間： ~32 hours 実験の流れ： Cells are exposed to Staurosporine for ~32 hours. Cells are fixed in 4% paraformaldehyde and stained with the DNA-binding dye Hoechst 33342. Cells are visualized under epifluorescence illumination, and the percentage of apoptotic cells (cells with condensed and fragmented DNA) is determined. (参考用のみ)
動物試験： ^[8]	- 合併動物モデル： Male Mongolian gerbils or male Wistar rats subjected to transient ischemia 投薬量： ~10 ng 投与方法： Stereotaxically administered into the bilateral CAl subfield of the hippocampus (参考用のみ)

参考

- 合併

溶解度 (25°C)

体外	DMSO	4 mg/mL (8.57 mM)
	Water	Insoluble
	Ethanol	Insoluble

* 溶解度測定はSelleck技術部門によって行われており、その他文献に示されている溶解度と差異がある可能性がありますが、同一ロットの生産工程で起きる正常な現象ですからご安心ください。

化学情報 Staurosporine (AM-2282) SDFをダウンロードする

分子量	466.53
化学式	C₂₈H₂₆N₄O₃
CAS No.	62996-74-1
Storage	3 years-20°C powder 2 years-80°C in solvent
別名	Antibiotic AM-2282, STS
Smiles	CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

投与溶媒組成計算器(クリア溶液)

ステップ１：実験データを入力してください。（実験操作によるロスを考慮し、動物数を1匹分多くして計算・調製することを推奨します）

投与量

mg/kg

動物平均体重

投与体積（動物毎）

動物数

匹

ステップ２：投与溶媒の組成を入力してください。（ロット毎に適した溶解組成が異なる場合があります。詳細については弊社までお問い合わせください）

% DMSO+ % + % Tween 80+ % ddH₂O

計算リセット

計算結果:

投与溶媒濃度： mg/ml；

DMSOストック溶液調製方法： mg 試薬を μL DMSOに溶解する（濃度 mg/mL，注：濃度が当該ロットのDMSO溶解度を超える場合はご連絡ください。）

投与溶媒調製方法：μL DMSOストック溶液に μL PEG300，を加え、完全溶解後μL Tween 80，を加えて完全溶解させた後 μL ddH₂O，を加え完全に溶解させます。

注意：１.ストック溶液に沈殿、混濁などがないことをご確認ください；
２.順番通りに溶剤を加えてください。次のステップに進む前に溶液に沈殿、混濁などがないことを確認してから加えてください。ボルテックス、ソニケーション、水浴加熱など物理的な方法で溶解を早めることは可能です。

便利ツール

モル濃度計算器

求めたい質量、体積または濃度を計算してください。

質量 (mg) = 濃度 (mM) x 体積 (mL) x 分子量 (g/mol)

モル濃度計算器方程式

質量

濃度

体積

分子量
=

×

×

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとSDS/COA（製品ページで利用可能な）。

希釈計算器

貯蔵液を準備するために必要な希釈率を計算してください。Selleck希釈計算器は、以下の方程式に基づきます：

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます：C1V1 = C2V2 ( 入力出力 )

C1

V1

C2

V2
×

=

×

常に貯蔵液を準備するとき、小びんラベルとSDS/COA（オンラインで利用できる）で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

連続希釈剤
初めの濃度：
稀釈倍数：

計算結果

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください：

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

質量	濃度	体積	分子量
=	×	×

技術サポート

ストックの作り方、阻害剤の保管方法、細胞実験や動物実験の際に注意すべき点など、製品を取扱う時に問い合わせが多かった質問に対しては取扱説明書でお答えしています。

Handling Instructions

他に質問がある場合は、お気軽にお問い合わせください。

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研究分野別

製品類型

Staurosporine (AM-2282)

文献中Selleckの製品使用例(111)

製品安全説明書

Antineoplastic and Immunosuppressive Antibiotics阻害剤の選択性比較

生物活性

お薦めの試験操作（参考用のみ）

参考

溶解度 (25°C)

化学情報 Staurosporine (AM-2282) SDFをダウンロードする

投与溶媒組成計算器(クリア溶液)

便利ツール

モル濃度計算器

質量 (mg) = 濃度 (mM) x 体積 (mL) x 分子量 (g/mol)

モル濃度計算器方程式

希釈計算器

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

連続希釈計算器方程式

連続希釈剤

計算結果

分子量计算器

総分子量：g/mol

モル濃度計算器

技術サポート