Staurosporine (AM-2282)

For research use only. Not for use in humans.

製品コードS1421 別名：Antibiotic AM-2282, STS

CAS No. 62996-74-1

Staurosporine (AM-2282, Antibiotic AM-2282, STS) is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM) in cell-free assays. Also shows inhibitory activities on other kinases, such as PKA, PKG, S6K, CaMKII, etc. Phase 3.

サイズ

価格(税別)

2mg	JPY 46800
5mg	JPY 85000
25mg	JPY 216560

最寄りの販売代理店を探す

東京
北海道
東北
北関東
南関東
東海
北信越
近畿
中国
四国
九州

お探しのディーラーが見当たらない場合は直接こちらのメールアドレスまでお問い合わせください：[email protected]

バルク問合せ

代表番号: 03-5615-9297|電子メール：[email protected]|よく尋ねられる質問

文献中Selleckの製品使用例(96)

製品安全説明書

Antineoplastic and Immunosuppressive Antibiotics阻害剤の選択性比較

生物活性

製品説明

ターゲット

PKCα ^[1] (Cell-free assay)	c-Fgr ^[2] (Cell-free assay)	phosphorylase kinase ^[2] (Cell-free assay)	PKCη ^[1] (Cell-free assay)	PKCγ ^[1] (Cell-free assay)	もっとクリックする
2 nM	2 nM	3 nM	4 nM	5 nM	もっとクリックする

体外試験

Staurosporine, a microbial alkaloid, significantly inhibits protein kinase C from rat brain with IC50 of 2.7 nM. Staurosporine displays strong inhibitory effect against HeLa S3 cells with IC50 of 4 nM. ^[1] Staurosporine also inhibits a variety of other protein kinases, including PKA, PKG, phosphorylase kinase, S6 kinase, Myosin light chain kinase (MLCK), CAM PKII, cdc2, v-Src, Lyn, c-Fgr, and Syk with IC50 of 15 nM, 18 nM, 3 nM, 5 nM, 21 nM, 20 nM, 9 nM, 6 nM, 20 nM, 2 nM, and 16 nM, respectively. ^[2] Staurosporine (1 μM) induces >90% apoptosis in PC12 cells. Consistently, Staurosporine treatment induces a rapid and prolonged elevation of intracellular free calcium levels [Ca²⁺]_i, accumulation of mitochondrial reactive oxygen species (ROS), and subsequent mitochondrial dysfunction. ^[3] The apoptosis of MCF7 cells induced by Staurosporine can be enhanced by the expression of functional caspase-3 via caspase-8 activation and Bid cleavage. ^[4] Staurosporine treatment at 1 μM only partially inhibits IL-3-stimulated Bcl2 phosphorylation but completely blocks PKC-mediated Bcl2 phosphorylation. ^[5] Staurosporine induces apoptosis of human foreskin fibroblasts AG-1518, depending on the lysosomal cathepsins D mediated cytochrome c release and caspase activation. ^[6] In addition to activating the classical mitochondrial apoptosis pathway, Staurosporine triggers a novel intrinsic apoptosis pathway, relying on the activation of caspase-9 in the absence of Apaf-1. ^[7]

細胞データ

Cell Lines	Assay Type	Concentration	Incubation Time	Activity Description	PMID
human colon carcinoma cell line HCT116	NIjUWYpHfW6ldHnvckBie3OjeR?=			MmHBR49v[2WwdILheIlwdiC{ZYH1bZJm\CCob4Kg[5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gZ49td25iY3HyZ4lvd22jIHPlcIwhdGmwZTDIR3QyOTZuIFnDOVA:PiCwTT6=	NWexOllVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW1N\|c{PDVpPkG1OVM4OzR3PD;hQi=>
human PBMC	NXnpOY9rTnWwY4Tpc44h[XO\|YYm=		MmjlNlQhcA>?	NITuXFRUfXCycnXzd4lwdiCxZjDJUFIheHKxZIXjeIlwdiCrbjDoeY1idiCSQl3DJIFnfGW{IEK0JIhzeyCkeTDFUGlUSSxiSVO1NF0yPiCwTT6=	MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDV6NUC0Okc,OTh3OEWwOFY9N2F-
endothelial cells	MW\GeY5kfGmxbjDhd5NigQ>?			M4rtOmVn\mWldHn2[UBld3OnIHHnZYlve3RicHzhd41qdm:pZX6gZYN1cX[jdH;yJIFkfGm4aYT5JJN1cW23bHH0[YQh[nlicHjvdoJwdCCnc4TldkBqdiCnbnTveIhmdGmjbDDj[YxteyxiRVS1NEA:KDdwNTFOwG0v	NYrjUplFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOEewPVA6PSd-OEewPVA6PTxxYU6=
Sf9 insect cells	MlrWSpVv[3Srb36gZZN{[Xl?			M4LJcmlvcGmkaYTpc44hd2ZicILveIVqdiCtaX7hd4UhSyhzOkHtbZh1fXKnIH;mJHBMSyCjbIDoZUAnKGKndHGpJIV5eHKnc4Pl[EBqdiCVZkmgbY5{\WO2IHPlcIx{NCCLQ{WwJF0hOC5yMjFOwG0v	M4fuVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzl6N{O2NFUoRjl6N{O2NFU9N2F-
LoVo cells	NIjtbZlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=			Mn7sRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiClb3zvckBk[W6lZYKgZ4VtdCCuaX7lJEhNd1[xIHPlcIx{MSC3c3nu[{BOXFRiYYPzZZktKEmFNUCgQUAxNjByMTFOwG0v	NYjZO3hKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUG1PVE2ODVpPkGxOVkyPTB3PD;hQi=>
umbilical vein endothelial cells	M1PIR2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7			MX\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKHWvYnnsbYNidCC4ZXnuJIVv\G:2aHXsbYFtKGOnbHzzJEhJXV[HQ4OpJJV{cW6pIF3UWEBie3OjeTygTWM2OCB;IECuNFA1KM7:TT6=	MnzhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF3OUG1NFUoRjFzNUmxOVA2RC:jPh?=
ST-486 cells	NV;YXWpSSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=			NEPxS4xCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIJ2emurdDDsfY1xcG:vYTDj[YxtKGyrbnWgLHNVNTR6NjDj[YxteylidYPpcochVVSWIHHzd4F6NCCLQ{WwJF0hOC5yMEeg{txONg>?	MkXHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF3OUG1NFUoRjFzNUmxOVA2RC:jPh?=
DLD-1 cells	NFT1TY1CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=			M2nZS2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iY3;sc44h[2GwY3XyJINmdGxibHnu[UApTEyGLUGgZ4VtdHNrIIXzbY5oKE2WVDDhd5NigSxiSVO1NEA:KDBwMEC5JO69VS5?	NFHnfm89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUW5NVUxPSd-MUG1PVE2ODV:L3G+
HEK293 cells	MkG0SpVv[3Srb36gZZN{[Xl?			NE\GfYRKdmirYnn0bY9vKG:oIGDLR{1j\XSjIFnJJI1m\GmjdHXkJGlNNThicnXs[YF{\SCocn;tJGhGUzJ7MzDj[YxteyCkeTDFUGlUSSxiSVO1NEA:KDBwMEe3JO69VS5?	M{PxRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{OUSxN\|MyLz5zMkm0NVM{OTxxYU6=
P19 cells	NEnodnNHfW6ldHnvckBie3OjeR?=			NHrRXHlKdmirYnn0bY9vKG:oIGDsZZRmdGW2LXTldol3\WRiZ4Lve5RpKG[jY4TvdkBz\WOncITvdkBqdiCSMUmgZ4VtdHNuIFnDOVAhRSByLkCwNkDPxE1w	MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd5MUSxPUc,OTV5N{G0NVk9N2F-
P19 cells	NWrrOVd7TnWwY4Tpc44h[XO\|YYm=			M4DB[2lvcGmkaYTpc44hd2ZiUHzheIVt\XRvZHXybZZm\CCpcn;3eIgh\mGldH;yJJJm[2WydH;yJIlvKFBzOTDj[YxteyxiSVO1NEA:KDBwMECyJO69VS5?	MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd5MUSxPUc,OTV5N{G0NVk9N2F-
P19 cells	NET4WGlHfW6ldHnvckBie3OjeR?=			NEnsTZhKdmirYnn0bY9vKG:oIGDyc5RmcW5iS3nuZZNmKEFiaX6gVFE6KGOnbHzzMEBKSzVyIE2gNE4xODRizszNMi=>	NIPBelc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe3NVQyQSd-MUW3O\|E1OTl:L3G+
P19 cells	M1q1b2Z2dmO2aX;uJIF{e2G7			Mn;rTY5pcWKrdHnvckBw\iCFYXzjbZVuN2OjbH3v[JVtcW5vZHXw[Y5l\W62IIDyc5RmcW5ia3nuZZNmKHS7cHWgTWkhcW5iUEG5JINmdGy\|LDDJR\|UxKD1iMD6wNFYh\|ryPLh?=	NHXkNlY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe3NVQyQSd-MUW3O\|E1OTl:L3G+
P19 cells	M2XRNWZ2dmO2aX;uJIF{e2G7			NV:3bGxoUW6qaXLpeIlwdiCxZjDDfYNtcW5vZHXw[Y5l\W62IHvpcoF{\SBzIHnuJHAyQSClZXzsd{whUUN3MDC9JFAvODB6IN88UU4>	M4\lbVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{exOFE6Lz5zNUe3NVQyQTxxYU6=
P19 cells	NUTOXnBtTnWwY4Tpc44h[XO\|YYm=			NUKxeFRtUW6qaXLpeIlwdiCxZjDWZZNkfWyjcjDlcoRwfGinbHnhcEBoem:5dHig[oFkfG:{IILlZ4VxfG:{IHnuJHAyQSClZXzsd{whUUN3MDC9JFAvODF2IN88UU4>	NWPMT\|F3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3O\|E1OTlpPkG1O\|cyPDF7PD;hQi=>
HEK293 cells	MUfGeY5kfGmxbjDhd5NigQ>?			MnTTTY5pcWKrdHnvckBw\iCLTD24JJJmdGWjc3WgZpkhUEWNMkmzJINmdGy\|IHX4dJJme3OrbnegVGtENWKndHGyMEBKSzVyIE2gNE4xPzdizszNMi=>	Ml;XQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5N{G0NVkoRjF3N{exOFE6RC:jPh?=
P19 cells	NE\JOGhHfW6ldHnvckBie3OjeR?=			MUHJcohq[mm2aX;uJI9nKEmwc4XsbY4hemWlZYD0c5Ihc2mwYYPlJIlvKFBzOTDj[YxteyxiSVO1NEA:KDBwMjFOwG0v	MlrDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5N{G0NVkoRjF3N{exOFE6RC:jPh?=
P19 cells	NGnoUG9HfW6ldHnvckBie3OjeR?=			M1jv[mlvcGmkaYTpc44hd2ZiQ3Hz[YlvKGurbnHz[UAyKGmwIGCxPUBk\WyuczygTWM2OCB;IEGuOEDPxE1w	NIDycJY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe3NVQyQSd-MUW3O\|E1OTl:L3G+
FL5.12-Akt1 cells	M1vJO2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7			NHTLO2ZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JGZNPS5zMj3Bb5QyKGOnbHzzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMkmg{txONg>?	MmXrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ2MEO2NlYoRjF4NECzOlI3RC:jPh?=
MiaPaCa-2 cells	M2qycmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7			MlvBRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDNbYFR[UOjLUKgZ4VtdHNiYomgUXRVKGG\|c3H5MEBKSzVyIE2gNE4{PyEQvF2u	MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjRyM{[yOkc,OTZ2MEO2NlY9N2F-
FL5.12-Akt1 cells	MmnWSpVv[3Srb36gZZN{[Xl?			MlPlRYN1cX[rdImgZYdicW6\|dDDHV2s{KGmwIF\MOU4yOi2Da4SxJINmdGy\|LDDFR\|UxKD1iMD60OkDPxE1w	MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjRyM{[yOkc,OTZ2MEO2NlY9N2F-
MiaPaCa-2 cells	MlXnRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?			NW\Gd\|RISW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNbYFR[UOjLUKgZ4VtdHNuIFnDOVAhRSByLkO3JO69VS5?	NUO2dFUzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[0NVM4QDBpPkG2OFE{PzhyPD;hQi=>
FL5.12-Akt1 cells	NYLjSXA5TnWwY4Tpc44h[XO\|YYm=			M2\mNmFkfGm4aYT5JIFo[Wmwc4SgS3NMOyCyaH;zdIhwenmuYYTpc44hcW5iRly1MlEzNUGtdEGgZ4VtdHNuIFXDOVAhRSByLkS2JO69VS5?	M3jRO\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NEGzO\|gxLz5zNkSxN\|c5ODxxYU6=
Sf21 cells	NEfXXHVHfW6ldHnvckBie3OjeR?=			MV7Jcohq[mm2aX;uJI9nKEqDS{Og[ZhxemW\|c3XkJIlvKFOoMkGgZ4VtdHNuIFnDOVAhRSByLkCwOkDPxE1w	MmPzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdyOEiwOVkoRjF5MEi4NFU6RC:jPh?=
U937 cells	M2rpXGN6fG:2b4jpZ4l1gSCjc4PhfS=>			NVvOb41kS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hXTl\|NzDj[YxteyxiSVO1NEA:KDJizszNMi=>	NEnGcG89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{C4PFA3Pyd-MUewPFgxPjd:L3G+
Sf9 cells	MW\GeY5kfGmxbjDhd5NigQ>?		MVqxJI1qdg>?	NGPpblhKdmirYnn0bY9vKG:oIHj1cYFvKE[7bjDlfJBz\XO\|ZXSgbY4hW2Z7IHPlcIx{KGGodHXyJFEhdWmwIHL5JGVNUVODIHnuJJBz\XOnbnPlJI9nKDFidX3vcE9NKEGWUDygTWM2OCB;IECuNFA2KM7:TT6=	M2PZUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{G1PFU{Lz5zN{OxOVg2OzxxYU6=
Sf9 cells	MmTESpVv[3Srb36gZZN{[Xl?		MlnnNlAhdWmwcx?=	MXvJcohq[mm2aX;uJI9nKGi3bXHuJGZ6diCneIDy[ZN{\WRiaX6gV4Y6KGOnbHzzJIFnfGW{IEKwJI1qdnNiYomgSWxKW0FiaX6gdJJme2WwY3Wgc4YhOSC3bX;sM2whSVSSLDDJR\|UxKD1iMD6wNVUh\|ryPLh?=	NUPndFVvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezNVU5PTNpPkG3N\|E2QDV\|PD;hQi=>
Sf9 cells	NVPBRXgxTnWwY4Tpc44h[XO\|YYm=		NHnCOY0yKG2rbh?=	NX3FNYNEUW6qaXLpeIlwdiCxZjDoeY1idiCIeX6g[ZhxemW\|c3XkJIlvKFOoOTDj[YxteyCjZoTldkAyKG2rbjDifUBGVEmVQTDpckBxemW\|ZX7j[UBw\iBzMDD1cY9tN0xiQWTQMEBKSzVyIE2gNE4xOzZizszNMi=>	M{XIWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{G1PFU{Lz5zN{OxOVg2OzxxYU6=
Sf9 cells	NWrZRpFFTnWwY4Tpc44h[XO\|YYm=		MoLmNlAhdWmwcx?=	M2f0XWlvcGmkaYTpc44hd2ZiaIXtZY4hTnmwIHX4dJJme3OnZDDpckBU\jliY3XscJMh[W[2ZYKgNlAhdWmwczDifUBGVEmVQTDpckBxemW\|ZX7j[UBw\iBzMDD1cY9tN0xiQWTQMEBKSzVyIE2gNE4xQDNizszNMi=>	MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzNzNUi1N{c,OTd\|MUW4OVM9N2F-
Sf9 cells	NVj2OFZoTnWwY4Tpc44h[XO\|YYm=		MXmxJI1qdg>?	MmDiTY5pcWKrdHnvckBw\iCqdX3hckBHgW5iZYjwdoV{e2WmIHnuJHNnQSClZXzsd{Bi\nSncjCxJI1qdiCkeTDFUGlUSSCrbjDwdoV{\W6lZTDv[kAyODBidX3vcE9NKEGWUDygTWM2OCB;IECuNlch\|ryPLh?=	NXPlXXBkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezNVU5PTNpPkG3N\|E2QDV\|PD;hQi=>
Sf9 cells	Ml3RSpVv[3Srb36gZZN{[Xl?		NYLpZnFxOjBibXnudy=>	NF71WXpKdmirYnn0bY9vKG:oIHj1cYFvKE[7bjDlfJBz\XO\|ZXSgbY4hW2Z7IHPlcIx{KGGodHXyJFIxKG2rboOgZpkhTUyLU1GgbY4heHKnc3XuZ4Uhd2ZiMUCwJJVud2xxTDDBWHAtKEmFNUCgQUAxNjVzIN88UU4>	M3zCZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{G1PFU{Lz5zN{OxOVg2OzxxYU6=
A549 cells	MV;DfZRwfG:6aXPpeJkh[XO\|YYm=		NUiwPHF6PzJiaB?=	NX7wN3NjS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA4OiCqcoOgZpkhe3WuZn;ybI9l[W2rbnWgRkBu\XSqb3SsJGdKPTBiPTCwMlAxOjRizszNMi=>	MnHvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2OES3O\|UoRjF6NEi0O\|c2RC:jPh?=
MDA-MB-231 cells	M3:4XGN6fG:2b4jpZ4l1gSCjc4PhfS=>		MVm3NkBp	NIfOWpNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOTEFvTVKtNlMyKGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIH3leIhw\CxiR1m1NEA:KDBwMEC3NUDPxE1w	Mn34QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2OES3O\|UoRjF6NEi0O\|c2RC:jPh?=
HT29 cells	NIjTcIREgXSxdH;4bYNqfHliYYPzZZk>		MU[3NkBp	MVfDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWFI6KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDzeYxnd3Kqb3ThcYlv\SCEIH3leIhw\CxiR1m1NEA:KDBwMEGwPUDPxE1w	MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDR6NEe3OUc,OTh2OES3O\|U9N2F-
MCF7 cells	NFXWeYNHfW6ldHnvckBie3OjeR?=			MWjJcohq[mm2aX;uJI9nKFCNQTDpckBpfW2jbjDNR2Y4KGOnbHzzJIJ6KGG{cnH5MYJie2WmIH\seY9z\XOlZX7j[UBie3OjeTygT4khRSByLkCwOUDPxE1w	NFPPb2c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOE[1OlM3QSd-MUi2OVY{Pjl:L3G+
MCF7 cells	NYexVpJCTnWwY4Tpc44h[XO\|YYm=			NWTZSJp[UW6qaXLpeIlwdiCxZjDQT2EhcW5iaIXtZY4hVUOINzDj[YxteyCkeTDhdpJigS2kYYPl[EBndHWxcnXzZ4Vv[2ViYYPzZZktKEmFNUCgQUAzKM7:TT6=	NIPLSXU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOE[1OlM3QSd-MUi2OVY{Pjl:L3G+
Sf9 cells	NWj4[HVtTnWwY4Tpc44h[XO\|YYm=			MVLJcohq[mm2aX;uJI9nKGi3bXHuJHN6cyCneIDy[ZN{\WRiaX6gV4Y6KGOnbHzzMEBKSzVyIE2gNE4xODNizszNMi=>	MmXKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh6MkO3PFQoRjF6OEKzO\|g1RC:jPh?=
Sf9 cells	NHL3fpdHfW6ldHnvckBie3OjeR?=			MV\Jcohq[mm2aX;uJI9nKGi3bXHuJHpCWDdyIHX4dJJme3OnZDDpckBU\jliY3XscJMtKEmFNUCgQUAxNjB3MzFOwG0v	NEHHU2M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEiyN\|c5PCd-MUi4NlM4QDR:L3G+
insect cells	NInHV2NHfW6ldHnvckBie3OjeR?=			NH3p[HlKdmirYnn0bY9vKG:oIHj1cYFvKHKnY3;tZolv[W62IGDpcVEh\XiycnXzd4VlKGmwIHnud4VkfCClZXzsd{BjgSCKVGLGMEBKSzVyIE2gNE4xOSEQvF2u	MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF5OUC3Okc,OTlzN{mwO\|Y9N2F-
HT-29 cells	MXfBdI9xfG:\|aYOgZZN{[Xl?		MUWyJIg>	NX3rN2dvUW6mdXP0bY9vKG:oIHHwc5B1d3OrczDpckBpfW2jbjDIWE0zQSClZXzsd{Bie3Onc4Pl[EBieyClaHHu[4UhcW5ibXn0c4Npd26mcnnhcEB1emGwc33lcYJz[W6nIIDveIVvfGmjbDDh[pRmeiB{IHjyd{BjgSCMQ{Ggd5RicW6rbnegZoF{\WRiZnz1c5Jme2OnbnPlJIF{e2G7LDDFSFUxKD1iMD6wNFI3KM7:TT6=	MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTR{MkKwOkc,OTl2MkKyNFY9N2F-
insect Sf21 cells	M4nBZ2Z2dmO2aX;uJIF{e2G7			M2rQWWlvcGmkaYTpc44hd2ZiSlHLN{BmgHC{ZYPz[YQhcW5iaX7z[YN1KFOoMkGgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iCkaX;0bY56dGG2ZXSgd5Vje3S{YYTlJJBpd3OyaH;yfYxifGmxbjygTWM2OCB;IECuNFA3KM7:TT6=	M{ntVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7NEK3NlA{Lz5zOUSyO\|IxOzxxYU6=
Jurkat cells	NEH3[XVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=			NHTRSmdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JGpCUzNiZYjwdoV{e2mwZzDJUFIue3SrbYXsZZRm\CCqdX3hckBLfXKtYYSgZ4VtdHNuIFnDOVAhRSByLkC3NUDPxE1w	M3;UO\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7NEK3NlA{Lz5zOUSyO\|IxOzxxYU6=
Jurkat cells	NITYUVJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=			NH\iSJNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JGpCUzNiZYjwdoV{e2mwZzDoeY1idiC{ZYP0bY5oKEq3cnvheEBk\WyuczygTWM2OCB;IECuN\|EyKM7:TT6=	NILCZ5o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUSyO\|IxOyd-MUm0NlczODN:L3G+
HUE cells	NWe1dpZmTnWwY4Tpc44h[XO\|YYm=		M2jwOlkxKG2rboO=	MlT0TY5pcWKrdHnvckBw\iCYRVfGVlIhcW5iSGXFJINmdGy\|IHHzd4V{e2WmIHHzJIlvcGmkaYTpc44hd2ZiVlXHSk1qdmS3Y3XkJIF2fG:yaH;zdIhwenmuYYTpc44hfHKnYYTl[EBnd3JiOUCgcYlveyCkZX\vdoUhXkWJRjDjbIFtdGWwZ3WgZpkhTUyLU1GsJGlEPTBiPTCwMlA4KM7:TT6=	NGjueYY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEG3NFE3Oyd-MkCxO\|AyPjN:L3G+
Sf9 cells	MoHtSpVv[3Srb36gZZN{[Xl?		NYDBVlR7PjBibXnudy=>	NVjSOoxrUW6qaXLpeIlwdiCxZjDoeY1idiC{ZXPvcYJqdmGwdDDHV3Qu\nW\|ZXSgUmlMKGW6cILld5Nm\CCrbjDT[lkh[2WubIOgZYZ1\XJiNkCgcYlveyCkeTDyZYRqd22ndILpZ{Bxem:2ZXnuJItqdmG\|ZTDhd5NigSxiSVO1NEA:KDJwMzFOwG0v	Mny1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB3OEC1OVIoRjJyNUiwOVUzRC:jPh?=
Sf21 cells	NWr6[I5wTnWwY4Tpc44h[XO\|YYm=	MlT2N\|AhfU1?		NX\LSGZYUW6qaXLpeIlwdiCxZjDoeY1idiCFSFuyJItqdmG\|ZTDlfJBz\XO\|ZXSgbY4hcW6\|ZXP0JHNnOjFiY3XscJMhfXOrbnegdIhwe3Cqbz3DVmVDfGmmZTDhd{B{fWK\|dILheIUh[XRiM{CgeW0tKEmFNUCgQUAxNjB{NzFOwG0v	MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN\|NEe5Okc,OjF\|M{S3PVY9N2F-
Sf21 cells	MnK2SpVv[3Srb36gZZN{[Xl?	NV[zSG1SOzBidV2=		MYLJcohq[mm2aX;uJI9nKGi3bXHuJJJm[2:vYnnuZY51KEmNSz3hcJBp[SCneIDy[ZN{\WRiaX6gbY5{\WO2IGPmNlEh[2WubIOgeZNqdmdicHjvd5Bpdy2XbHnnbJQuUWujcIDhRk1idHCqYTDhd{B{fWK\|dILheIUh[XRiM{CgeW0tKEmFNUCgQUAxNjB\|OTFOwG0v	NUnxVGYxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzN\|Q4QTZpPkKxN\|M1Pzl4PD;hQi=>
Sf21 cells	NYHuO\|l1TnWwY4Tpc44h[XO\|YYm=	M1vVXlMxKHWP		MVXJcohq[mm2aX;uJI9nKGi3bXHuJJJm[2:vYnnuZY51KEmNSz3i[ZRiKGW6cILld5Nm\CCrbjDpcpNm[3RiU3[yNUBk\WyuczD1d4lv\yCyaH;zdIhwNVWuaXfoeE1Kc2GycHHCMYFteGijIHHzJJN2[nO2cnH0[UBifCB\|MDD1UUwhUUN3MDC9JFAvPDlizszNMi=>	MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN\|NEe5Okc,OjF\|M{S3PVY9N2F-
HeLa cells	MWPDfZRwfG:6aXPpeJkh[XO\|YYm=		MkK3OFghcA>?	MoTnR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG\|c3H5MEBKSzVyIE2gNE4xODByMESg{txONg>?	NUfrNJJvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzPFgyQTFpPkKxN\|g5OTlzPD;hQi=>
MCF7 cells	MmXWR5l1d3SxeHnjbZR6KGG\|c3H5		NFnFVlg1QCCq	Ml64R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWNHPyClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKGG\|c3H5MEBKSzVyIE2gNE4xPSEQvF2u	MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN6OEG5NUc,OjF\|OEixPVE9N2F-
HT-29 cells	M1jWWGZ2dmO2aX;uJIF{e2G7		NUjLWpV7OiCq	M33wOmVn\mWldDDvckBucXSxY3jvcoRzcWGuIH3lcYJz[W6nIIDveIVvfGmjbDDpckBpfW2jbjDIWE0zQSClZXzsd{Bi\nSncjCyJIhzeyC3c3nu[{BLSy1zIIP0ZYlvcW6pIHL5JIZtfW:{ZYPj[Y5k\SCjc4PhfUwhUUN3MDC9JFAvODB{IN88UU4>	MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR{OEO3OUc,OjF2MkizO\|U9N2F-
HeLa cells	NV7j[G5PS3m2b4TvfIlkcXS7IHHzd4F6		NWfK[HlpPDhiaB?=	M4jsdmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODByMEC0JO69VS5?	NHXpWIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUS4PFY2PSd-MkG0PFg3PTV:L3G+
MCF7 cells	MXrDfZRwfG:6aXPpeJkh[XO\|YYm=		M3fGS\|Q5KGh?	M3i5eGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJG1ETjdiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODVizszNMi=>	NVSxd4llRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0PFg3PTVpPkKxOFg5PjV3PD;hQi=>
HT-29 cells	M1nydWZ2dmO2aX;uJIF{e2G7			NV36N\|Y5UW6qaXLpeIlwdiCxZjDtbZRw[2ixbnTybYFtKG2nbXLyZY5mKHCxdHXueIlidCCrbjDoeY1idiCKVD2yPUBk\WyuczD1d4lv\yCMQ{Gg[JlmKHO2YXnubY5oKGK7IH\seY9z\XOlZX7j[UBxdGG2ZTDy[YFl\XJiYYPzZZktKEmFNUCgQUAxNjByMkWg{txONg>?	NUT1fmtlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG1NVMzQTNpPkKxOVE{Ojl\|PD;hQi=>
SF268 cells	NFP0SXhEgXSxdH;4bYNqfHliYYPzZZk>		MmHxOFghcA>?	Moj2R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gV2YzPjhiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFAvODR2IN88UU4>	NGLQUHg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWxN\|I6PCd-MkG1NVMzQTR:L3G+
CHOK1 cells	NVL0VpZuS3m2b4TvfIlkcXS7IHHzd4F6		NGr6dXg1QCCq	Moe0R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR2hQUzFiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JHNTSiCjc4PhfUwhT0l3MDC9JFAvOTNizszNMi=>	M1vyZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUGzNlk1Lz5{MUWxN\|I6PDxxYU6=
H460 cells	MUPDfZRwfG:6aXPpeJkh[XO\|YYm=		NEPjbVI1QCCq	MlL5R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTFQ3OCClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG\|c3H5MEBIUTVyIE2gN{43KM7:TT6=	NX3yTYhbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG1NVMzQTRpPkKxOVE{Ojl2PD;hQi=>
HT-29 cells	Mke3R5l1d3SxeHnjbZR6KGG\|c3H5		NIewbm81QCCq	MUnDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDIWE0zQSClZXzsd{Bi\nSncjC0PEBpenNiYomgV3JDKGG\|c3H5MEBIUTVyIE2gN{43KM7:TT6=	NVzqV2I3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG1NVMzQTRpPkKxOVE{Ojl2PD;hQi=>
MCF7 cells	NIizU4JEgXSxdH;4bYNqfHliYYPzZZk>		MUO0PEBp	MXPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO\|YYmsJGdKPTBiPTCxNUDPxE1w	MlTqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUOyPVQoRjJzNUGzNlk1RC:jPh?=
SW1116 cells	NUfPb\|ZoTnWwY4Tpc44h[XO\|YYm=		M1\kVlI1KGh?	MmDxTY5pcWKrdHnvckBw\iC2ZXzvcYVz[XOnIHnuJIh2dWGwIGPXNVEyPiClZXzsd{Bi\nSncjCyOEBpenNiYomgWHJCWC2SQ2KtSWxKW0FiYYPzZZktKEmFNUCgQUA5NjN{IN88UU4>	NH:3bXo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUm2NlUzOyd-MkG5OlI2OjN:L3G+
HT-29 cells	Mm\YRZBweHSxc3nzJIF{e2G7		MUmyJIg>	NUf4TpFVUW6mdXP0bY9vKG:oIHHwc5B1d3OrczDpckBpfW2jbjDIWE0zQSClZXzsd{Bie3Onc4Pl[EBz\WS3Y4Tpc44hd2ZibXn0c4Npd26mcnnhcEBu\W2kcnHu[UBxd3SnboTpZYwh[W[2ZYKgNkBpenNiYomgeZNqdmdiSlOxJJN1[WmwaX7nJIJ6KG[udX;y[ZNk\W6lZTDj[YxtNWKjc3XkJIF{e2G7LDDFSFUxKD1iMD6wNFI3KM7:TT6=	NIOwd4o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUm3N\|ExOSd-MkG5O\|MyODF:L3G+
LoVo cells	NH\YSY1CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		M4flVFQ5KHSxIEeyJIg>	MoXxRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCOb2\vJINmdGy\|IHHmeIVzKDR6IITvJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjByMTFOwG0v	MnvpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzOEK5NlkoRjJ{MUiyPVI6RC:jPh?=
ST486 cells	M1nTemFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7		M2rWUVQ5KHSxIEeyJIg>	NWPufI5KSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTWFQ5PiClZXzsd{Bi\nSncjC0PEB1dyB5MjDodpMh[nliTWTUJIF{e2G7LDDJR\|UxKD1iMD6wNFch\|ryPLh?=	M2HTbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUiyPVI6Lz5{MkG4NlkzQTxxYU6=
DLD1 cells	MVTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		NET4OHI1QCC2bzC3NkBp	NFPMVmhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFTMSFEh[2WubIOgZYZ1\XJiNEigeI8hPzJiaILzJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMEC5JO69VS5?	NX;Edpc{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxPFI6OjlpPkKyNVgzQTJ7PD;hQi=>
B16F10 cells	MXTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		M1\CfVQ5KGh?	MoLjRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDtc5V{\SCEMU\GNVAh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IEKuPFIh\|ryPLh?=	MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjVyM{O2OEc,OjJ3MEOzOlQ9N2F-
MCF7 cells	NX3tdmdRSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=		NUH6R5VxPDhiaB?=	NX3zNXM3SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO\|YYmsJGlEPTBiPTCzMlA4KM7:TT6=	NXyySWFVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1NFM{PjRpPkKyOVA{OzZ2PD;hQi=>
A431 cells	M2[2d2N6fG:2b4jpZ4l1gSCjc4PhfS=>		M4\uVFI1KGh?	NGfUbZVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPDNzIHPlcIx{KGGodHXyJFI1KGi{czD1d4lv\yCDbn7lfIlvKF[nRlnUR{9xem:yaXTpeY0hcW:maXTlJJN1[WmwaX7nJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMEeg{txONg>?	MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV2MUC1NUc,OjJ3NEGwOVE9N2F-
MCF7 cells	NWDYWpplS3m2b4TvfIlkcXS7IHHzd4F6		NUmxSGV[OjRiaB?=	NFzNU3NEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFI1KGi{czD1d4lv\yCDbn7lfIlvKF[nRlnUR{9xem:yaXTpeY0hcW:maXTlJJN1[WmwaX7nJIJ6KE2WVDDhd5NigSxiSVO1NEA:KDBwMUig{txONg>?	NGf6S2Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkW0NVA2OSd-MkK1OFExPTF:L3G+
BJ cells	NHXz[WpEgXSxdH;4bYNqfHliYYPzZZk>		MUG3NkBp	NUK0W4dVS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSkpiY3XscJMh[W[2ZYKgO\|IhcHK\|IHL5JGNidGOnaX6gRW0h[XO\|YYmsJGlEPTBiPTCwMlAxOiEQvF2u	NITsbIc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkmyNVA5OSd-MkK5NlExQDF:L3G+
CEM cells	MkHUR5l1d3SxeHnjbZR6KGG\|c3H5		NIfPd4k4OiCq	MYrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDDSW0h[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IFPhcINmcW5iQV2gZZN{[XluIFnDOVAhRSByLkCyN{DPxE1w	NVXmOYR7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5NlExQDFpPkKyPVIyODhzPD;hQi=>
MCF7 cells	MUnDfZRwfG:6aXPpeJkh[XO\|YYm=		NHv2Wlc4OiCq	NX;he3M3S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA4OiCqcoOgZpkhS2GuY3XpckBCVSCjc4PhfUwhUUN3MDC9JFAvODZ2IN88UU4>	NYPCd4JnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5NlExQDFpPkKyPVIyODhzPD;hQi=>
HeLa cells	M3jiTGN6fG:2b4jpZ4l1gSCjc4PhfS=>		M33S[lczKGh?	MmXMR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{Bi\nSncjC3NkBpenNiYomgR4Ft[2WrbjDBUUBie3OjeTygTWM2OCB;IECuNVc2KM7:TT6=	NEG2N\|A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkmyNVA5OSd-MkK5NlExQDF:L3G+
HepG2 cells	NFnYTmFHfW6ldHnvckBie3OjeR?=		NF;LOVMzPCCq	NV7aZ4Z7UW6qaXLpeIlwdiCxZjD0[YxwdWW{YYPlJIlvKGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFI1KGi{czDifUBVWkGSLWDDVk1GVEmVQTDhd5NigSxiSVO1NEA:KDRwMUSg{txONg>?	MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzBzOEC5Okc,OjNyMUiwPVY9N2F-
SW1116 cells	M4LhWmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7		NFrnNXQ1QCCq	Mn;TRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6\|dDDoeY1idiCVV{GxNVYh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBu\XSqb3SsJGlEPTBiPTC0Mlk2KM7:TT6=	NUCyO2lvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwNVgxQTZpPkKzNFE5ODl4PD;hQi=>
HepG2 cells	NGLWcXdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		MlPjOFghcA>?	NVnkZZhjSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[ZBIOiClZXzsd{Bi\nSncjC0PEBpenNiYomgUXRVKG2ndHjv[EwhUUN3MDC9JFYvPzNizszNMi=>	M1n3eVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|MEG4NFk3Lz5{M{CxPFA6PjxxYU6=
BGC823 cells	NFfjdmJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		NF6wWZg1QCCq	M{nCZmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQlfDPFI{KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQhdWW2aH;kMEBKSzVyIE2gOk45OyEQvF2u	M{LDcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ\|MEG4NFk3Lz5{M{CxPFA6PjxxYU6=
HeLa cells	MV7BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>?		NIHTbJc1QCCq	MW\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEinTHGgZ4VtdHNiYX\0[ZIhPDhiaILzJIJ6KE2WVDDt[ZRpd2RuIFnDOVAhRSB7LkGyJO69VS5?	MonOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyMUiwPVYoRjJ\|MEG4NFk3RC:jPh?=
HCT116 cells	MVzGeY5kfGmxbjDhd5NigQ>?			NETCbmNKdmirYnn0bY9vKG:oIGTOTWsudWWmaXH0[YQhXEOIND;i[ZRiNWOjc3XpckB1emGwc3PybZB1cW:wIHnuJIh2dWGwIFjDWFEyPiClZXzsd{BjgSCkZYThMYxi[3SjbXHz[UBz\XCxcoTldkBo\W6nIHHzd4F6NCCLQ{WwJF0hOC5yM{mg{txONg>?	NIPqWVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{KzNlA3OCd-MkOyN\|IxPjB:L3G+
HepG2 cells	MVjGeY5kfGmxbjDhd5NigQ>?		MoLKOFghcA>?	NVXvVZgxUW6qaXLpeIlwdiCxZjD0[YxwdWW{YYPlJIlvKGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFQ5KGi{czDifUBVWkGSLWDDVk1GVEmVQTygTWM2OCB;IEiuN{DPxE1w	MoHMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{N{m4OlQoRjJ\|Mke5PFY1RC:jPh?=
SW1116 cells	MV7GeY5kfGmxbjDhd5NigQ>?		Mn;xNlQhcA>?	MU\Jcohq[mm2aX;uJI9nKHSnbH;t[ZJie2ViaX6gbJVu[W5iU2exNVE3KGOnbHzzJIFnfGW{IEK0JIhzeyCkeTDUVmFRNVCFUj3FUGlUSSCjc4PhfUwhUUN3MDC9JFQvOThizszNMi=>	M2j6ZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2Mki2O\|YyLz5{NEK4Olc3OTxxYU6=
KE-97 cells	M3;3[WN6fG:2b4jpZ4l1gSCjc4PhfS=>		MkTIO\|IhcA>?	NXSwRXBJS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hU0VvOUegZ4VtdHNiYX\0[ZIhPzJiaILzJIJ6KEOnbHzUbZRz\S2JbH:gcJVucW6nc3PlcpQh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVAhRSByLkGzJO69VS5?	M4DNO\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{K4Nlg{Lz5{NEOyPFI5OzxxYU6=
Jurkat cells	NH7oeIJEgXSxdH;4bYNqfHliYYPzZZk>		M{OzdVczKGh?	MVTDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDKeZJs[XRiY3XscJMh[W[2ZYKgO\|IhcHK\|IHL5JGNmdGyWaYTy[U1IdG9ibIXtbY5me2OnboSgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUCgQUAxNjF2IN88UU4>	Ml62QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR\|MkiyPFMoRjJ2M{K4Nlg{RC:jPh?=
HuH7 cells	NYDOWJBxS3m2b4TvfIlkcXS7IHHzd4F6		NYDKc3FUPzJiaB?=	NUDo[W1VS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUHWKNzDj[YxteyCjZoTldkA4OiCqcoOgZpkhS2WubGTpeJJmNUeubzDseY1qdmW\|Y3XueEBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwMkOg{txONg>?	NVrpcJBRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSzNlgzQDNpPkK0N\|I5Ojh\|PD;hQi=>
BGC823 cells	NVLie3gxS3m2b4TvfIlkcXS7IHHzd4F6		NYHPOVdHPzJiaB?=	M17C[mN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGJISzh{MzDj[YxteyCjZoTldkA4OiCqcoOgZpkhS2WubGTpeJJmNUeubzDseY1qdmW\|Y3XueEBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwM{ig{txONg>?	NGfQVYM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEOyPFI5Oyd-MkSzNlgzQDN:L3G+
MCF7 cells	M{L5OWN6fG:2b4jpZ4l1gSCjc4PhfS=>		NFv3fGE4OiCq	MX7DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEeyJIhzeyCkeTDD[YxtXGm2cnWtS4xwKGy3bXnu[ZNk\W62IHPlcIwhfmmjYnnsbZR6KGG\|c3H5MEBKSzVyIE2gNE42OiEQvF2u	MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN{OEK4N{c,OjR\|MkiyPFM9N2F-
NIH/3T3 cells	MV3DfZRwfG:6aXPpeJkh[XO\|YYm=		NXXXRXZFQTZiaB?=	Mk[2R5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgUmlJNzOWMzDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOC5{IN88UU4>	MmDFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR\|NkG1NlEoRjJ2M{[xOVIyRC:jPh?=
A2780 cells	NF;5[VFEgXSxdH;4bYNqfHliYYPzZZk>		NX7sWplmQTZiaB?=	NWHjb5RIS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTJ5OECgZ4VtdHNiYX\0[ZIhQTZiaILzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDBwMjFOwG0v	NGfGUGU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO2NVUzOSd-MkSzOlE2OjF:L3G+
HT-29 cells	NGe0ZXlEgXSxdH;4bYNqfHliYYPzZZk>		NHXG[o46PiCq	NHTKR4dEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJXC1{OTDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwJF0hOC5{IN88UU4>	NVvBeVRJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSzOlE2OjFpPkK0N\|YyPTJzPD;hQi=>
8505C cells	MXzDfZRwfG:6aXPpeJkh[XO\|YYm=		NF;ER\|Y6PiCq	NYLOcGl6S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hQDVyNVOgZ4VtdHNiYX\0[ZIhQTZiaILzJIJ6KFOUQjDhd5NigSxiSVO1NEA:KDBwMjFOwG0v	NHH3Oo49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO2NVUzOSd-MkSzOlE2OjF:L3G+
518A2 cells	M4DyNmN6fG:2b4jpZ4l1gSCjc4PhfS=>		MmPCPVYhcA>?	M1jBXGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJFUyQEF{IHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEmFNUCgQUAxNjJizszNMi=>	MmLqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR\|NkG1NlEoRjJ2M{[xOVIyRC:jPh?=
MCF7 cells	NGjYW2REgXSxdH;4bYNqfHliYYPzZZk>		M1Gyflk3KGh?	MV\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEm2JIhzeyCkeTDTVmIh[XO\|YYmsJGlEPTBiPTCwMlQh\|ryPLh?=	NXzpT4xPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSzOlE2OjFpPkK0N\|YyPTJzPD;hQi=>
A549 cells	NIezU5BEgXSxdH;4bYNqfHliYYPzZZk>		MVO5OkBp	MUPDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBOVQ6KGOnbHzzJIFnfGW{IEm2JIhzeyCkeTDTVmIh[XO\|YYmsJGlEPTBiPTCwMlYh\|ryPLh?=	NIjOS3I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO2NVUzOSd-MkSzOlE2OjF:L3G+
V79 MZ cells	M17x[2Z2dmO2aX;uJIF{e2G7			MX3Jcohq[mm2aX;uJI9nKGi3bXHuJIFt\G:\|dHXyc45mKHO7boToZZNmKGW6cILld5Nm\CCrbjDWO\|khVVpiY3XscJMh[XO\|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBidGSxc4Tldo9v\SC\|eX70bIV{cXNuIFnDOVAhRSByLkCxNUDPxE1w	NV;sUW4{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS0NlI2OTlpPkK0OFIzPTF7PD;hQi=>
HEK293 cells	MlTvR5l1d3SxeHnjbZR6KGG\|c3H5		NVPUemNEPzJiaB?=	Mo\LR5l1d3SxeHnjbZR6KGGpYXnud5QhUEWNMkmzJINmdGy\|IHHmeIVzKDd{IHjyd{BjgSCFZXzsWIl1\XKJbH:gZZN{[XluIFnDOVAhRSByLkC1OkDPxE1w	NWf1V3g5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3OlMzPjJpPkK0O\|Y{OjZ{PD;hQi=>
HeLa cells	NFG4NXhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?=		M{f4T\|I1KHSxIES4JIg>	NUHyZpZ2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDI[WxiKGOnbHzzJIFnfGW{IEK0JJRwKDR6IHjyd{BjgSCFQ1utPEBie3OjeTygTWM2OCB;IEKuO\|Ih\|ryPLh?=	NIPzOmI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEe5NlgyOSd-MkS3PVI5OTF:L3G+
A549 cells	MnzWRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl?		NXTROYE1OjRidH:gOFghcA>?	M{XVO2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQUW0PUBk\WyuczDh[pRmeiB{NDD0c{A1QCCqcoOgZpkhS0ONLUigZZN{[XluIFnDOVAhRSB\|LkC1JO69VS5?	M1TENFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{myPFEyLz5{NEe5NlgyOTxxYU6=
HepG2 cells	M4TKVGN6fG:2b4jpZ4l1gSCjc4PhfS=>			NGDpZ\|VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJ\XCJMjDj[YxteyxiRVO1NEA:KDJizszNMi=>	NX;LUnJFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWzNVY{OTdpPkK1N\|E3OzF5PD;hQi=>
Raji cells	M{fqemN6fG:2b4jpZ4l1gSCjc4PhfS=>			MV3DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDSZYpqKGOnbHzzMEBGSzVyIE2gNkDPxE1w	NUHJPXNGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWzNVY{OTdpPkK1N\|E3OzF5PD;hQi=>
BJ cells	NVv3[FlqS3m2b4TvfIlkcXS7IHHzd4F6			MYrDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDCTkBk\WyuczygSWM2OCB;IEKg{txONg>?	MkGzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV\|MU[zNVcoRjJ3M{G2N\|E4RC:jPh?=
HEK293 cells	MXLDfZRwfG:6aXPpeJkh[XO\|YYm=			NVv4dm1sS3m2b4TvfIlkcXS7IHHnZYlve3RiSFXLNlk{KGOnbHzzMEBGSzVyIE2gNkDPxE1w	M1frUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3M{G2N\|E4Lz5{NUOxOlMyPzxxYU6=
A549 cells	M3G5N2N6fG:2b4jpZ4l1gSCjc4PhfS=>		MmGxOFghcA>?	NXPRS25xS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTV2OTDj[YxteyCjZoTldkA1QCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5yMjFOwG0v	NGPHXW49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUiyOVk{PCd-MkW4NlU6OzR:L3G+
HeLa cells	MV;DfZRwfG:6aXPpeJkh[XO\|YYm=		NXXjdFF6PDhiaB?=	M3j1O2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmVGFiY3XscJMh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFAvODJ3IN88UU4>	MkDuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6MkW5N\|QoRjJ3OEK1PVM1RC:jPh?=
PC3 cells	NHX2VGpEgXSxdH;4bYNqfHliYYPzZZk>		MYe0PEBp	NVvvS\|UyS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hWEN\|IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUCgQUAxNjB\|MTFOwG0v	MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh{NUmzOEc,OjV6MkW5N\|Q9N2F-
MGC-803 cells	M4TRbWZ2dmO2aX;uJIF{e2G7		Mlq5NlQhcA>?	MVHJcohq[mm2aX;uJI9nKHSnbH;t[ZJie2ViaX6gbJVu[W5iTVfDMVgxOyClZXzsd{Bi\nSncjCyOEBpenNiYomgWHJCWC2SQ2KtSWxKW0FiYYPzZZktKEmFNUCgQUA5Njl5IN88UU4>	M2nmNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4OUCwOlU3Lz5{NkmwNFY2PjxxYU6=
Sf9 insect cells	NH;FbVNHfW6ldHnvckBie3OjeR?=		M2XqSFExKG2rboO=	NUXtOpZVUW6qaXLpeIlwdiCxZjDOMZRmem2rbnHsJGdUXCC2YXfn[YQhemWlb33ibY5idnRiZoXscE1t\W6pdHigbJVu[W5iQ1jLNUBmgHC{ZYPz[YQhcW5iYnHjeYxwfmm{dYOgV4Y6KGmwc3XjeEBk\WyuczDh[pRmeiBzMDDtbY5{KGK7IHz1cYlv\XOlZX70JGFFWC2JbH:gZZN{[XluIFnDOVAhRSByLkCwNVIh\|ryPLh?=	Ml65QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdyOEmyNVEoRjJ5MEi5NlEyRC:jPh?=
Sf21 cells	NXXBfZRvTnWwY4Tpc44h[XO\|YYm=		Mn[yOlAhdWmwcx?=	NGf5dmRKdmirYnn0bY9vKG:oIHj1cYFvKHKnY3;tZolv[W62IFrBT\|Ih\XiycnXzd4VlKGmwIGPmNlEh[2WubIOgZZN{\XO\|ZXSgZZMhemWmdXP0bY9vKGmwIGXsbYdpfC2FQVfBS2FKTVSGS1XZXXRXU0RicHjvd5Bpd3K7bHH0bY9vKHC{ZT3pcoN2[mG2ZXSgZoVnd3KnIIP1ZpN1emG2ZTDh[IRqfGmxbjDhcoQhdWWjc4Xy[YQh[W[2ZYKgOlAhdWmwczDifUBNSU6FRTDk[ZRm[3Srb36gcYV1cG:mLDDJR\|UxKD1iMD6wNFIh\|ryPLh?=	MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzF\|N{O1PUc,OjdzM{ezOVk9N2F-
Neuro2a cells	MX3DfZRwfG:6aXPpeJkh[XO\|YYm=		Mme2O\|IhcA>?	MmjER5l1d3SxeHnjbZR6KGGpYXnud5QhdW:3c3WgUoV2em9{YTDj[YxteyCjc4Pld5Nm\CCjczDj[YxtKH[rYXLpcIl1gSCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5yMUGzJO69VS5?	M3m1TVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MUWyOFI4Lz5{OEG1NlQzPzxxYU6=
MDA-MB-231 cells	M4P6WGZ2dmO2aX;uJIF{e2G7		NFnaRlQyPiCq	M3K2[mlvcGmkaYTpc44hd2ZicnX0bY5w[myjc4TvcYEheHKxdHXpckBxcG:\|cHjvdplt[XSrb36gbY4hcHWvYX6gUWRCNU2ELUKzNUBk\WyuczDh[pRmeiBzNjDodpMh[nliSH;lZ4h{fCB\|M{O0NkB{fGGrbnnu[{Bj[XOnZDDmcJVwemW\|Y3XuZ4Uh[XO\|YYmsJGlEPTBiPTCwMlA3PiEQvF2u	M{\xdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEOxN\|QzLz5{OESzNVM1OjxxYU6=
Sf9 insect cells	MorsSpVv[3Srb36gZZN{[Xl?		MoTwNlAhdWmwcx?=	M{nGV2lvcGmkaYTpc44hd2ZicnXjc41jcW6jboSgbJVu[W5iTj30[ZJucW6jbHz5JGdUXC22YXfn[YQhTUeIUjDMPFU5Wi:WN{mwUU9EPzl5UzD0dolxdGVibYX0ZY51KGW6cILld5Nm\CCrbjDiZYN2dG:4aYL1d{BqdiCVZkmgbY5{\WO2IHPlcIx{KHC{ZXnuZ5Vj[XSnZDDmc5IhOjBibXnud{Bnd2yub4fl[EBjgSCjZHTpeIlwdiCxZjDbN\|NRZS2DVGCgcYVie3W{ZXSgZYZ1\XJiMjDodpMh[nliZnnseIVzNWKrbnTpcochdWW2aH;kMEBKSzVyIE2gNE4xODB{OTFOwG0v	M1PIOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEiyNVUyLz5{OES4NlE2OTxxYU6=
HEK293 cells	M3XSRWN6fG:2b4jpZ4l1gSCjc4PhfS=>		NXLHU5ZtPzJiaB?=	M4jycmN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEiHS{K5N{Bk\WyuczDhd5Nme3OnZDDhd{Bl\WO{ZXHz[UBqdiClZXzsJJZq[WKrbHn0fUBi\nSncjC3NkBpenNiYomgR4VtdFSrdHXyJGdtdyCudX3pcoV{[2WwdDDhd5NigSxiQ1O1NEA:KDBwMECzOVQh\|ryPLh?=	M2jaeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NkK0O\|AyLz5{OE[yOFcxOTxxYU6=
BT549 cells	M3vpcWN6fG:2b4jpZ4l1gSCjc4PhfS=>		NEjtXm8zPCCq	NWr2bJBPS3m2b4TvfIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gRnQ2PDliY3XscJMhcW6ldXLheIVlKG[xcjCyOEBpenNiYomgUXRVKGG\|c3H5MEBKSzVyIE2gNE4xQCEQvF2u	M4rJPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6N{C1OFMzLz5{OEewOVQ{OjxxYU6=
MDA-MB-468 cells	NX;sS\|FVS3m2b4TvfIlkcXS7IHHzd4F6		NWW3[G9[OjRiaB?=	NWnTV4JsS3m2b4TvfIlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUS2PEBk\WyuczDpcoN2[mG2ZXSg[o9zKDJ2IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSByLkG1JO69VS5?	MkfDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5MEW0N\|IoRjJ6N{C1OFMzRC:jPh?=
MDA-MB-231 cells	NFPsZlJEgXSxdH;4bYNqfHliYYPzZZk>		NX3TTYhXOjRiaB?=	M4DZemN6fG:2b4jpZ{Bi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3ERU1OSi1{M{GgZ4VtdHNiaX7jeYJifGWmIH\vdkAzPCCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwJF0hOC5{NDFOwG0v	MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDdyNUSzNkc,Ojh5MEW0N\|I9N2F-
Vero cells	MV\DfZRwfG:6aXPpeJkh[XO\|YYm=		MVSyJIRigXN?	MYfDfZRwfG:6aXPpeJkh[WejaX7zeEBC\nKrY3HuJIdz\WWwIH3vcotmgSCYZYLvJINmdGy\|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiClZXzsJJZq[WKrbHn0fUBi\nSncjCyJIRigXNiYomgZ4VtdC22aYTldk1odG9ibIXtbY5me2OnboSgZZN{[XluIGTDOVAhRSByLkCwNlQh\|ryPLh?=	MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd4M{[0OUc,Ojh5NkO2OFU9N2F-
L929 cells	NV3TUZJrSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO\|YYm=		NVnTc\|lXPSCmYYnz	NXjxO\|loSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBud3W\|ZTDMPVI6KGOnbHzzJIFnfGW{IEWg[IF6eyCkeTDXV3QuOSCjc4PhfUwhUUN3MDC9JFAvOiEQvF2u	Ml3sQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh7NU[5NVUoRjJ6OUW2PVE2RC:jPh?=
KB-3-1 cells	M2DDOGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7		NYXvbXFPPSCmYYnz	MVXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEuELUOtNUBk\WyuczDh[pRmeiB3IHThfZMh[nliV2PUMVEh[XO\|YYmsJGlEPTBiPTCwMlIh\|ryPLh?=	MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDl3NkmxOUc,Ojh7NU[5NVU9N2F-
MCF7 cells	M4Hme2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7		NYrh[nlrPSCmYYnz	NYPu[5RYSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IEWg[IF6eyCkeTDXV3QuOSCjc4PhfUwhUUN3MDC9JFEvQCEQvF2u	NGHHUpU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEm1OlkyPSd-Mki5OVY6OTV:L3G+
FS4-LTM cells	M2D1PWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7		M1zKZlI1KGh?	MVTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKE[VND3MWG0h[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IGfTWE0yKGG\|c3H5MEBKSzVyIE2gNk45KM7:TT6=	M2raT\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OUW2PVE2Lz5{OEm1OlkyPTxxYU6=
Vero cells	NFnNbYhEgXSxdH;4bYNqfHliYYPzZZk>		MoHwNkBl[Xm\|	MUHDfZRwfG:6aXPpeJkh[WejaX7zeEBC\nKrY3HuJIdz\WWwIH3vcotmgSCYZYLvJINmdGy\|IHHmeIVzKDJiZHH5d{BjgSCFZXzsWIl1\XJvR3zvJIx2dWmwZYPj[Y51KGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR\|UxKD1iMD6wNFI1KM7:TT6=	NFnwflU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEm5N\|ExPid-Mki5PVMyODZ:L3G+
HepG2 cells	MnfKR5l1d3SxeHnjbZR6KGG\|c3H5	NUPnSFNTOTByIIXN	MUWzJIRigXN?	M{jNR2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhmeEd{IHPlcIx{KGG2IEGwNEB2VSCjZoTldkA{KGSjeYOgZpkhS2WubGTpeIVzNUeubzDseY1qdmW\|Y3XueEBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NEA:KDBwMEG4JO69VS5?	M4fSZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6OUmzNVA3Lz5{OEm5N\|ExPjxxYU6=
NIH/3T3 cells	NHnzPJZEgXSxdH;4bYNqfHliYYPzZZk>		NV:5WXZLQTZiaB?=	NH2xS\|JEgXSxdH;4bYNqfHliYXfhbY5{fCCvb4Xz[UBPUUhxM2SzJINmdGy\|IHHmeIVzKDl4IHjyd{BjgSCVUlKgZZN{[XluIFXDOVAhRSByLkCwPEDPxE1w	MmfuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzOUe3N\|AoRjJ7MUm3O\|MxRC:jPh?=
518A2 cells	MXrDfZRwfG:6aXPpeJkh[XO\|YYm=		MV[5OkBp	MmDUR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gOVE5STJiY3XscJMh[W[2ZYKgPVYhcHK\|IHL5JHNTSiCjc4PhfUwhTUN3MDC9JFAvODNizszNMi=>	Mn[5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzOUe3N\|AoRjJ7MUm3O\|MxRC:jPh?=
A549 cells	NV[zOXdoS3m2b4TvfIlkcXS7IHHzd4F6		NG[1NZk6PiCq	NFjwWo1EgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEWFNUCgQUAxNjB2IN88UU4>	MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF7N{ezNEc,OjlzOUe3N\|A9N2F-
MCF7 cells	MYXDfZRwfG:6aXPpeJkh[XO\|YYm=		M2jIelk3KGh?	NUS3WGhHS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hVUOINzDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCHQ{WwJF0hOC5zIN88UU4>	MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTF7N{ezNEc,OjlzOUe3N\|A9N2F-
A2780 cells	M{[4b2N6fG:2b4jpZ4l1gSCjc4PhfS=>		MX65OkBp	MY\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDBNlc5OCClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG\|c3H5MEBGSzVyIE2gNE4yOiEQvF2u	NHTwR4g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUG5O\|c{OCd-MkmxPVc4OzB:L3G+
HT-29 cells	MnjWR5l1d3SxeHnjbZR6KGG\|c3H5		Mn3QPVYhcA>?	NYXIeHZCS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUFRvMkmgZ4VtdHNiYX\0[ZIhQTZiaILzJIJ6KFOUQjDhd5NigSxiRVO1NEA:KDBwMUWg{txONg>?	MlXDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjlzOUe3N\|AoRjJ7MUm3O\|MxRC:jPh?=
PC3 cells	NF3meGZEgXSxdH;4bYNqfHliYYPzZZk>			MlTMR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gVGM{KGOnbHzzJIJ6KHO3bH\vdohw\GGvaX7lJGIh[XO\|YYmsJGlEPTBiPTCwMlAyPyEQvF2u	NUnjV\|BHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkmzPFkyOjJpPkK5N\|g6OTJ{PD;hQi=>
HCT116 cells	NHrzfW5EgXSxdH;4bYNqfHliYYPzZZk>			Mlj2R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGNVOTF4IHPlcIx{KGK7IIP1cIZwemixZHHtbY5mKEJiYYPzZZktKEmFNUCgQUAxNjB3NTFOwG0v	NHzNXVA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUO4PVEzOid-MkmzPFkyOjJ:L3G+
insect cells	MXjGeY5kfGmxbjDhd5NigQ>?		MWizNEBucW6\|	MlL1TY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCSRFfGVoJmfGFiZYjwdoV{e2WmIHnuJIlve2WldDDj[YxteyC3c3nu[{BWdGmpaIStVI9tgSCJQWTbSWF[MDF8MUqxLX1vKGG\|IIP1ZpN1emG2ZTDh[pRmeiB\|MDDtbY5{KGK7IFzBUmNGKG2ndHjv[EwhUUN3MDC9JFAvODByN{[g{txONg>?	M4PkSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
Sf9 insect cells	MVTGeY5kfGmxbjDhd5NigQ>?		NYDVU2lYPjBibXnudy=>	MnSzTY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCNRGKg[ZhxemW\|c3XkJIlvKFOoOTDpcpNm[3RiY3XscJMhfXOrbnegWYxq\2i2LVPBS2FISUmHVFTLSXl[XF[NRDDhd{B{fWK\|dILheIUh[W[2ZYKgOlAhdWmwczDifUBNSU6FRTDt[ZRpd2RuIFnDOVAhRSByLkCwNlEh\|ryPLh?=	NHf4e5I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUW0PVg{Pid-Mkm1OFk5OzZ:L3G+
insect cells	M{XPR2Z2dmO2aX;uJIF{e2G7		M2HKdlExKG2rboO=	MV\Jcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKFO{YzDlfJBz\XO\|ZXSgbY4hcW6\|ZXP0JINmdGy\|IIXzbY5oKFWuaXfoeE1Rd2y7IFfBWHtGSVlqMUqxPlEqZW5iYYOgd5Vje3S{YYTlJIFnfGW{IEGwJI1qdnNiYomgUGFPS0VibXX0bI9lNCCLQ{WwJF0hOC5yMEWg{txONg>?	NWCyVo9TRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1OFk5OzZpPkK5OVQ6QDN4PD;hQi=>
insect cells	NFjQdm1HfW6ldHnvckBie3OjeR?=		NILaWHEyPSCvaX7z	NX\LVJBpUW6qaXLpeIlwdiCxZjDy[YNwdWKrbnHueEBpfW2jbjDDSGsyN0O7Y3zpckBDKGW6cILld5Nm\CCrbjDpcpNm[3RiY3XscJMhfXOrbnegWYxq\2i2LVPGSmtPUV[WUGLUVHBRW1GJSz3hcYll\SCjczDzeYJ{fHKjdHWgZYZ1\XJiMUWgcYlveyCkeTDMRW5ETSCvZYToc4QtKEmFNUCgQUAxNjB{NTFOwG0v	NVH6ZoxrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1OFk5OzZpPkK5OVQ6QDN4PD;hQi=>
insect cells	NV2yNIt4TnWwY4Tpc44h[XO\|YYm=		Mn7sNVUhdWmwcx?=	MUHJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKEOGS{GvR5lkdGmwIFKg[ZhxemW\|c3XkJIlvKGmwc3XjeEBk\WyuczD1d4lv\yCXbHnnbJQuS0[IS17JWnRRWlSSUGDTVWdMNWGvaXTlJIF{KHO3YoP0doF1\SCjZoTldkAyPSCvaX7zJIJ6KEyDTlPFJI1mfGixZDygTWM2OCB;IECuNFI2KM7:TT6=	MnrtQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3NEm4N\|YoRjJ7NUS5PFM3RC:jPh?=
Sf9 insect cells	MYLGeY5kfGmxbjDhd5NigQ>?		M{W0R\|E2KG2rboO=	Mn:2TY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCIbISxJIV5eHKnc4Pl[EBqdiCVZkmgbY5{\WO2IHPlcIx{KHW\|aX7nJHVtcWeqdD3UT{Bx\XC2aXTlJIF{KHO3YoP0doF1\SCjZoTldkAyPSCvaX7zJIJ6KEyDTlPFJI1mfGixZDygTWM2OCB;IECuNFM2KM7:TT6=	MmnxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3NEm4N\|YoRjJ7NUS5PFM3RC:jPh?=
Sf21 insect cells	M1HmTWZ2dmO2aX;uJIF{e2G7		MkHlNVUhdWmwcx?=	MXPJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKEG3cn;yZU1CKGW6cILld5Nm\CCrbjDT[lIyKGmwc3XjeEBk\WyuczD1d4lv\yCXbHnnbJQuWlKUU1zMSUBieyC\|dXLzeJJifGViYX\0[ZIhOTVibXnud{BjgSCOQV7DSUBu\XSqb3SsJGlEPTBiPTCwMlA{QSEQvF2u	M2K3V\|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
insect cells	M3ftSmZ2dmO2aX;uJIF{e2G7		NETHRoU3OCCvaX7z	MYLJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKEGNVEGg[ZhxemW\|c3XkJIlvKGmwc3XjeEBk\WyuczD1d4lv\yCFUlXCeIll\SCjczDzeYJ{fHKjdHWgZYZ1\XJiNkCgcYlveyCkeTDMRW5ETSCvZYToc4QtKEmFNUCgQUAxNjB3NjFOwG0v	Mk\aQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3NEm4N\|YoRjJ7NUS5PFM3RC:jPh?=
Sf9 insect cells	NVSyVIJuTnWwY4Tpc44h[XO\|YYm=		M4CydlYxKG2rboO=	NFT1XnBKdmirYnn0bY9vKG:oIILlZ49u[mmwYX70JIh2dWGwIF\BT{BmgHC{ZYPz[YQhcW5iU3[5JIlve2WldDDj[YxteyC3c3nu[{BWdGmpaIStWGsheGWydHnk[UBieyC\|dXLzeJJifGViYX\0[ZIhPjBibXnud{BjgSCOQV7DSUBu\XSqb3SsJGlEPTBiPTCwMlA3OiEQvF2u	NXTw[I9FRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1OFk5OzZpPkK5OVQ6QDN4PD;hQi=>
insect cells	M1SwVGZ2dmO2aX;uJIF{e2G7		NVTJOGJsPjBibXnudy=>	Mn60TY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCDQlyg[ZhxemW\|c3XkJIlvKGmwc3XjeEBk\WyuczD1d4lv\yCXbHnnbJQuXEticHXweIll\SCjczDzeYJ{fHKjdHWgZYZ1\XJiNkCgcYlveyCkeTDMRW5ETSCvZYToc4QtKEmFNUCgQUAxNjJ7IN88UU4>	M2fjTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
insect cells	NV3LUnhGTnWwY4Tpc44h[XO\|YYm=		NUXFPVJRPjBibXnudy=>	MUDJcohq[mm2aX;uJI9nKHKnY3;tZolv[W62IHj1cYFvKGNvTVXUJIV5eHKnc4Pl[EBqdiCrboPlZ5Qh[2WubIOgeZNqdmdiVXzp[4h1NUODR1HHRWlGXESNRWnZWHZMTCCjczDzeYJ{fHKjdHWgZYZ1\XJiNkCgcYlveyCkeTDMRW5ETSCvZYToc4QtKEmFNUCgQUAxNjNzIN88UU4>	M1y3OlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NUS5PFM3Lz5{OUW0PVg{PjxxYU6=
PC3 cells	MnXFR5l1d3SxeHnjbZR6KGG\|c3H5		M2\D[\|czKGh?	NFmyRZVEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBRSzNiY3XscJMh[W[2ZYKgO\|IhcHK\|IHL5JHNTSiCjc4PhfUwhUUN3MDC9JFAvODN7IN88UU4>	MkDJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3NUixNVkoRjJ7NUW4NVE6RC:jPh?=
Sf9 cells	M3TZT2Z2dmO2aX;uJIF{e2G7		Ml\pOFUhdWmwcx?=	Mmq5TY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCFLYTldo1qdmGuIFjpd{11[WepZXSvUk11\XKvaX7hcEBIW1RvdHHn[4VlKEWJRmKgLFY3QCC2bzCxNlExKHKnc3nkeYV{MSCneIDy[ZN{\WRiaX6gZoFkfWyxdnnyeZMhcW6oZXP0[YQhW2Z7IHPlcIx{KHW\|aX7nJHBwdHlvKFfseUwhXHm{KTDhd{B{fWK\|dILheIUhdWWjc4Xy[YQh[W[2ZYKgOFUhdWmwdYTld{BjgSCNaX7hd4UuT2yxIHz1cYlv\XOlZX70JIF{e2G7LDDJR\|UxKD1iMD6wOFch\|ryPLh?=	Ml7SQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl7MEK3NVkoRjJ7OUCyO\|E6RC:jPh?=
Sf9 cells	MWDGeY5kfGmxbjDhd5NigQ>?		NGLacZg1PSCvaX7z	Ml62TY5pcWKrdHnvckBw\iC{ZXPvcYJqdmGwdDDoeY1idiCQLYTldo1qdmGuIFfTWE11[WepZXSgTGVTOiBqNke5JJRwKDF{NUWgdoV{cWS3ZYOpJIV5eHKnc4Pl[EBqdiCkYXP1cI93cXK3czDpcoZm[3SnZDDT[lkh[2WubIOgeZNqdmdiUH;sfU0pT2y3LDDUfZIqKGG\|IIP1ZpN1emG2ZTDt[YF{fXKnZDDh[pRmeiB2NTDtbY52fGW\|IHL5JGtqdmG\|ZT3HcI8hdHWvaX7ld4NmdnRiYYPzZZktKEmFNUCgQUAxNjB4MEig{txONg>?	NU\tbm95RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC\|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm5NFI4OTlpPkK5PVAzPzF7PD;hQi=>
HT-29 cells	NX32b\|VpTnWwY4Tpc44h[XO\|YYm=		MXezJIg>	Ml3uTY5pcWKrdHnvckBw\iCvaYTvZ4hwdmS{aXHsJI1mdWK{YX7lJJBwfGWwdHnhcEBqdiCqdX3hckBJXC1{OTDj[YxteyCjZoTldkA{KGi{czDifUBLSy1zIIP0ZYlvcW6pIHLhd4VlKG[udX;y[ZNk\W6lZTDhd5NigSxiSVO1NEA:KDBwMEKg{txONg>?	M13FblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMEW3NVU2Lz5\|MEC1O\|E2PTxxYU6=
Sf9 cells	MnnYSpVv[3Srb36gZZN{[Xl?			MYnJcohq[mm2aX;uJI9nKE5vdHXycYlv[WxiRlzBS{11[WepZXSgbJVu[W5iZoXscE1t\W6pdHigR2RMOTJiKEGgeI8hOTR7MDDy[ZNq\HWnczmvUk11\XKvaX7hcEBJcXNvdHHn[4VlKEO7Y1ugLFEhfG9iNUiwJJJme2mmdXXzLUBmgHC{ZYPz[YQhcW5iU3[5JINmdGy\|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiCDVGCt[IVx\W6mZX70JHVNcWeqdD20SU1DWDFiKGTodlM4N1SqckS2LUB{fWK\|dILheIUheGWydHnk[UBxcG:\|cHjvdplt[XSrb36gdJItKEmFNUCgQUAxNjB3MzFOwG0v	MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODB4N{O1PEc,OzByNkezOVg9N2F-
Sf9 cells	MXvGeY5kfGmxbjDhd5NigQ>?			NF2x[\|ZKdmirYnn0bY9vKG:oIF6teIVzdWmwYXygSmxCTy22YXfn[YQhcHWvYX6g[pVtdC2uZX7neIghS0SNMUKgLFEhfG9iMUS5NEBz\XOrZIXld{kwVi22ZYLtbY5idCCKaYOteIFo\2WmIFP5Z2shMDFidH:gOVgxKHKnc3nkeYV{MSCneIDy[ZN{\WRiaX6gV4Y6KGOnbHzzJIF{e2W\|c3XkJIF{KHKnZIXjeIlwdiCrbjDBWHAu\GWyZX7k[Y51KFWOaXfoeE01TS2EUEGgLHRpejN5L2TodlQ3MSC\|dXLzeJJifGVicHXweIll\SCyaH;zdIhwenmuYYTpc44heHJuIFnDOVAhRSByLkC1N{DPxE1w	MoLkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzByNkezOVgoRjNyME[3N\|U5RC:jPh?=
Sf9 cells	NGewOIJHfW6ldHnvckBie3OjeR?=			MWnJcohq[mm2aX;uJI9nKE5vdHXycYlv[WxiRlzBS{11[WepZXSgbJVu[W5iZoXscE1t\W6pdHigR2RMOTNiKEGgeI8hOTVzMjDy[ZNq\HWnczmvUk11\XKvaX7hcEBJcXNvdHHn[4VlKEO7Y1ugLFEhfG9iNUiwJJJme2mmdXXzLUBmgHC{ZYPz[YQhcW5iU3[5JINmdGy\|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiCDVGCt[IVx\W6mZX70JHVNcWeqdD20SU1DWDFiKGTodlM4N1SqckS2LUB{fWK\|dILheIUheGWydHnk[UBxcG:\|cHjvdplt[XSrb36gdJItKEmFNUCgQUAxNjB3NzFOwG0v	NEnIXmM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9\|MEC2O\|M2QCd-M{CwOlc{PTh:L3G+
Sf9 cells	NGDVUGdHfW6ldHnvckBie3OjeR?=			M{TQU2lvcGmkaYTpc44hd2ZiTj30[ZJucW6jbDDGUGFINXSjZ3fl[EBpfW2jbjDmeYxtNWynbnf0bEBETEtzMzCoNUB1dyBzNUGyJJJme2mmdXXzLU9PNXSncn3pcoFtKEircz30ZYdo\WRiQ4njT{ApOSC2bzC1PFAhemW\|aXT1[ZMqKGW6cILld5Nm\CCrbjDT[lkh[2WubIOgZZN{\XO\|ZXSgZZMhemWmdXP0bY9vKGmwIFHUVE1l\XCnbnTlcpQhXUyrZ3j0MVRGNUKSMTCoWIhzOzdxVHjyOFYqKHO3YoP0doF1\SCyZYD0bYRmKHCqb4PwbI9zgWyjdHnvckBxeixiSVO1NEA:KDBwMEW3JO69VS5?	MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODB4N{O1PEc,OzByNkezOVg9N2F-
HCT116 cells	MXTDfZRwfG:6aXPpeJkh[XO\|YYm=		NVi4UWs2PDhiaB?=	NHHlR5VEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBJS1RzMU[gZ4VtdHNiYYPz[ZN{\WRiYYOg[IVkemWjc3WgbY4h[2WubDD2bYFjcWyrdImgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OCB;IECuNFMh\|ryPLh?=	M1z1PVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMUC2NlkyLz5\|MEGwOlI6OTxxYU6=
Huh7.5 cells	NX7iNWtyS3m2b4TvfIlkcXS7IHHzd4F6		NGq2U3Q1QCCq	NWnG[3h3S3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUHWqNz61JINmdGy\|IHHzd4V{e2WmIHHzJIRm[3KnYYPlJIlvKGOnbHygeoli[mmuaYT5JIFnfGW{IES4JIhzeyCkeTDNWHQh[XO\|YYmsJGlEPTBiPTCwMlYh\|ryPLh?=	MmTTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzBzME[yPVEoRjNyMUC2NlkyRC:jPh?=
K562 cells	MkHJR5l1d3SxeHnjbZR6KGG\|c3H5		NIntPWk1QCCq	NGPtOHpEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBMPTZ{IHPlcIx{KGG\|c3Xzd4VlKGG\|IHTlZ5Jm[XOnIHnuJINmdGxidnnhZoltcXS7IHHmeIVzKDR6IHjyd{BjgSCPVGSgZZN{[XluIFnDOVAhRSBzLkeg{txONg>?	MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODFyNkK5NUc,OzBzME[yPVE9N2F-
LO2 cells	M3HMRmN6fG:2b4jpZ4l1gSCjc4PhfS=>		M4X1clQ5KGh?	MY\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDMU\|Ih[2WubIOgZZN{\XO\|ZXSgZZMh\GWlcnXhd4UhcW5iY3XscEB3cWGkaXzpeJkh[W[2ZYKgOFghcHK\|IHL5JG1VXCCjc4PhfUwhUUN3MDC9JFkvPSEQvF2u	MkW5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzBzME[yPVEoRjNyMUC2NlkyRC:jPh?=

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アッセイ

Methods	Test Index	PMID
Western blot	FAK / RIP; PubMed: 15121855 Mol Cell Biol Western blot (WB) analysis of BT-20 and BT-474 lysates treated with staurosporine (200 nM). Control cells were treated with dimethyl sulfoxide for 18 h. p-Akt / Akt / PARP /Cleaved PARP; PubMed: 24174874 Int J Nanomedicine Western blot analysis for Akt, P-Akt, and cleaved poly(ADP-ribose) polymerase. U87 cells were incubated with 200 nM, 10 nM, and 0.1 nM of staurosporine encapsulated in liposomes and staurosporine for 32 hours. Ambra1; PubMed: 24587252 PLoS One SW620 cells treated with various doses of staurosporine for 6 h. Ambra1 levels were measured by Western blot.	15121855 24174874 24587252
Growth inhibition assay	Cell viability; PubMed: 25215174 Oxid Med Cell Longev Staurosporine reduces cerebellar astrocytes viability. (a) Cerebellar astrocytes were treated with staurosporine 0.1 μM, 0.25 μM, and 0.5 μM for 24 h and the cell viability was measured by MTT transformation. (b) Cerebellar astrocytes were treated with staurosporine 0.5 μM for 6, 12, and 24 h and the cell viability was measured by MTT transformation. Data are presented as mean ± SEM of four independent experiments. ∗ is significantly different from control (P < 0.05).	25215174
Immunofluorescence	Phalloidin / Type II collagen; PubMed: 22684244 Exp Mol Med Cell were cultured in the absence (a-f) or presence of staurosporine (STSN, 5 × 10-9M) or cytochalasin D (CD, 1 µg/ml) for 1 (upper panel) or 2 (lower panel) days at low density and stained for F-actin (Phalloidin) and type II collagen (Type II). STSN: Staurosporine. Tubulin / Actin; PubMed: 25215174 Oxid Med Cell Longev Morphological changes of astrocytes induced by St are evidenced by the rearrangement of cytoskeletal proteins. Astrocytes were treated with St (0.5 μM) for 12 hours and then were labelled with rhodamine-phalloidin or immunostained for tubulin. Representative images of phase contrast, rhodamine-phalloidin, and tubulin are shown in control and St treated astrocytes. Scale bar represents 50 μm. FAK 4.47; PubMed: 15121855 Mol Cell Biol BT-20 or BT-474 cell culture were plated on six-well plates and were treated with staurosporine (200 nM) after 24 h. After 6 h of treatment, cells were immunostained with anti-FAK 4.47 antibody (white arrowheads mark some focal adhesions). cleaved-caspase 3; PubMed: 19840952 Cardiovasc Res Representative images (×1000 magnification) showing vehicle treated (C) and staurosporine treated (D) cells stained with anti-cleaved caspase 3 antibody and DAPI. Annexin; PubMed: 15140398 Neoplasia Induction of apoptosis with staurosporine resulting in activation of the ICE-NIRF probe. Gli36 cells were treated with 50 µM staurosporine for 24 hours (A-C) or with the same percentage of DMSO (0.01%) to which experimental wells were exposed (D-488nm laser, E-633nm laser and F-bright field). To examine the role of caspase-1 in staurosporine-induced apoptosis and probe activation, cells were coincubated in caspase-1 inhibitor (10 µM) and staurosporine (G-I). Staurosporine induces apoptosis, indicated by the positive annexin staining viewed with the 488-nm laser (A), which colocalized with activated probe viewed with the 633-nm laser (B). Coincubation of the caspase-1 inhibitor with staurosporine did not completely block apoptosis, indicated by the relatively higher number of apoptotic cells stained with annexin (G), as those that activated the probe (H). Magnification, x 40; scale bar, 50 µM. Pyk2; PubMed: 19880522 J Biol Chem Pyk2 translocates to the nucleus upon staurosporine addition to ID8 cells. Confocal immunofluorescent analysis of endogenous Pyk2 upon DMSO (control) or 1 μm staurosporine addition for 2 h. The scale bar is 10 μm.	22684244 25215174 15121855 19840952 15140398 19880522

体内試験

In the gerbil and rat ischemia models, Staurosporine pretreatment (0.1-10 ng) before ischemia prevents neuronal damage in a dose-dependent manner, suggesting the involvement of PKC in CAl pyramidal cell death after ischemia. ^[8]

お薦めの試験操作（参考用のみ）

キナーゼ試験： ^[1]	- 合併 Enzyme assay and binding assay: Protein kinase C is assayed in a reaction mixture (0.25 mL) containing 5 μmol of Tris/HCl, pH 7.5, 2.5 μmol of magnesium acetate, 50 μg of histone II S, 20 μg of phosphatidylserine, 0.88 μg of diolein, 125 nmol of CaCl₂, 1.25 nmol of [γ-³²]ATP (5-10 × 10⁴ cpm/nmol) and 5 μg of partially purified enzyme. The binding of [³H]PDBu to protein kinase C is determined: Reaction mixture (200 μL contained 4 μmo1 of Tris/malate, pH 6.8, 20 μmol of KCl, 30 nmol of CaC1₂, 20 μg of phosphatidylserine, 5 μg of partially purified protein kinase C, 0.5% (final concentration) of DMSO,10 pmol of [³H]PDBu (l-3 × 10⁴ cpm/pmol) and 10 μL of various amounts of Staurosporine.
細胞試験： ^[3]	- 合併細胞株： PC12 濃度： Dissolved in DMSO, final concentration 1 μM 反応時間： ~32 hours 実験の流れ： Cells are exposed to Staurosporine for ~32 hours. Cells are fixed in 4% paraformaldehyde and stained with the DNA-binding dye Hoechst 33342. Cells are visualized under epifluorescence illumination, and the percentage of apoptotic cells (cells with condensed and fragmented DNA) is determined. (参考用のみ)
動物試験： ^[8]	- 合併動物モデル： Male Mongolian gerbils or male Wistar rats subjected to transient ischemia 投薬量： ~10 ng 投与方法： Stereotaxically administered into the bilateral CAl subfield of the hippocampus (参考用のみ)

参考

- 合併

溶解度 (25°C)

体外	DMSO	4 mg/mL (8.57 mM)
	Water	Insoluble
	Ethanol	Insoluble

* 溶解度測定はSelleck技術部門によって行われており、その他文献に示されている溶解度と差異がある可能性がありますが、同一ロットの生産工程で起きる正常な現象ですからご安心ください。

化学情報 Staurosporine (AM-2282) SDFをダウンロードする

分子量	466.53
化学式	C₂₈H₂₆N₄O₃
CAS No.	62996-74-1
Storage	3 years-20°C powder 2 years-80°C in solvent
別名	Antibiotic AM-2282, STS
Smiles	CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

投与溶媒組成計算器(クリア溶液)

ステップ１：実験データを入力してください。（実験操作によるロスを考慮し、動物数を1匹分多くして計算・調製することを推奨します）

投与量

mg/kg

動物平均体重

投与体積（動物毎）

動物数

匹

ステップ２：投与溶媒の組成を入力してください。（ロット毎に適した溶解組成が異なる場合があります。詳細については弊社までお問い合わせください）

% DMSO+ % + % Tween 80+ % ddH₂O

計算リセット

計算結果:

投与溶媒濃度： mg/ml；

DMSOストック溶液調製方法： mg 試薬を μL DMSOに溶解する（濃度 mg/mL，注：濃度が当該ロットのDMSO溶解度を超える場合はご連絡ください。）

投与溶媒調製方法：μL DMSOストック溶液に μL PEG300，を加え、完全溶解後μL Tween 80，を加えて完全溶解させた後 μL ddH₂O，を加え完全に溶解させます。

注意：１.ストック溶液に沈殿、混濁などがないことをご確認ください；
２.順番通りに溶剤を加えてください。次のステップに進む前に溶液に沈殿、混濁などがないことを確認してから加えてください。ボルテックス、ソニケーション、水浴加熱など物理的な方法で溶解を早めることは可能です。

便利ツール

モル濃度計算器

求めたい質量、体積または濃度を計算してください。

質量 (mg) = 濃度 (mM) x 体積 (mL) x 分子量 (g/mol)

モル濃度計算器方程式

質量

濃度

体積

分子量
=

×

×

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとSDS/COA（製品ページで利用可能な）。

希釈計算器

貯蔵液を準備するために必要な希釈率を計算してください。Selleck希釈計算器は、以下の方程式に基づきます：

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます：C1V1 = C2V2 ( 入力出力 )

C1

V1

C2

V2
×

=

×

常に貯蔵液を準備するとき、小びんラベルとSDS/COA（オンラインで利用できる）で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

連続希釈剤
初めの濃度：
稀釈倍数：

計算結果

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください：

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

質量	濃度	体積	分子量
=	×	×

技術サポート

ストックの作り方、阻害剤の保管方法、細胞実験や動物実験の際に注意すべき点など、製品を取扱う時に問い合わせが多かった質問に対しては取扱説明書でお答えしています。

Handling Instructions

他に質問がある場合は、お気軽にお問い合わせください。

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研究分野別

製品類型

Staurosporine (AM-2282)

文献中Selleckの製品使用例(96)

製品安全説明書

Antineoplastic and Immunosuppressive Antibiotics阻害剤の選択性比較

生物活性

お薦めの試験操作（参考用のみ）

参考

溶解度 (25°C)

化学情報 Staurosporine (AM-2282) SDFをダウンロードする

投与溶媒組成計算器(クリア溶液)

便利ツール

モル濃度計算器

質量 (mg) = 濃度 (mM) x 体積 (mL) x 分子量 (g/mol)

モル濃度計算器方程式

希釈計算器

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

連続希釈計算器方程式

連続希釈剤

計算結果

分子量计算器

総分子量：g/mol

モル濃度計算器

技術サポート