3-Methyladenine (3-MA)

For research use only. Not for use in humans.

製品コードS2767 別名:NSC 66389

3-Methyladenine (3-MA)化学構造

CAS No. 5142-23-4

3-Methyladenine (3-MA, NSC 66389) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM in HeLa cells; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. 3-Methyladenine (3-MA) is successfully used to suppress mitophagy. Solutions of 3-MA are best fresh-prepared by heating.

サイズ 価格(税別)  
JPY 13600
JPY 63400
最寄りの販売代理店を探す

お探しのディーラーが見当たらない場合は直接こちらのメールアドレスまでお問い合わせください:[email protected]

バルク問合せ

文献中Selleckの製品使用例(649)

製品安全説明書

PI3K阻害剤の選択性比較

生物活性

製品説明 3-Methyladenine (3-MA, NSC 66389) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM in HeLa cells; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. 3-Methyladenine (3-MA) is successfully used to suppress mitophagy. Solutions of 3-MA are best fresh-prepared by heating.
ターゲット
Vps34 [1]
(HeLa cells)
PI3Kγ [1]
(HeLa cells)
25 μM 60 μM
体外試験

The slight preference for Vps34 prevention by 3-Methyladenine probably arises from a hydrophobic ring specific to Vps34, which encircles the 3-methyl group of 3-Methyladenine. [1] 3-Methyladenine has been reported to cause cancer cell death under both normal and starvation conditions. 3-Methyladenine could also suppress cell migration and invasion independently of its ability to inhibit autophagy, implying that 3-Methyladenine possesses functions other than autophagy suppression. 3-Methyladenine elicits caspase-dependent cell death that is independent of autophagy inhibition. Treatment with 5 mM 3-Methyladenine reduces the percentage of glucose-starved HeLa cells displaying GFP-LC3 puncta to 23%. The levels of LC3-I are increasing and the levels of LC3-II are decreasing between 12 and 48 hours in cells that are treated with 3-Methyladenine. Conversion of LC3-I to LC3-II is suppressed by 3-Methyladenine. Treatment of HeLa cells with 3-Methyladenine at 2.5 mM or 5 mM for one day does not affect cell viability, whereas treatment with 10 mM 3-Methyladenine for one day causes a 25.0% decrease in cell viability. Treatment of cells with 2.5, 5 or 10 mM 3-Methyladenine for two days causes 11.5%, 38.0% and 79.4% decrease in viability, respectively. 3-Methyladenine decreases cell viability in a time- and dose-dependent manner. 3-Methyladenine significantly shortens the duration of nocodazole-induced-prometaphase arrest. [2] Suppression of autophagy by 3-Methyladenine inhibits SU11274-induced cell death. [3] Prolonged treatment with 3-Methyladenine (up to 9 hours) induces significant LC3 I to II conversion in wild type MEFs. Prolonged treatment with 3-Methyladenine, but not wortmannin, markedly increases GFP-LC3 punctuation/aggregation. 3-Methyladenine-induced LC3 conversion and free GFP liberation are ATG7-dependent. 3-Methyladenine treatment leads to evident increase of p62 protein level. 3-Methyladenine increases the p62 level even in Atg5−/− MEFs as well as in cells with DOX-mediated deletion of ATG5. 3-Methyladenine inhibits class I and class III PI3K in different temporal patterns. 3-Methyladenine-induced LC3 I to LC3 II conversion is dramatically compromised in Tsc2−/− cells compared with wild type cells.3-Methyladenine disrupts the anti-autophagic function of mTOR complex 1. [4]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
K562 NH\pOVJHfW6ldHnvckBCe3OjeR?= MYGxNI1O M{Wwc|Fp MU\k[YNz\WG|ZYOgeIhmKGW6cILld5Nqd25ib3[gUGM{NUmLIHHu[EB1cGViZn;ycYF1cW:wIH;mJIF2fG:yaHHnc5NwdWW| MmLTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6NkSwN|coRjJzOE[0NFM4RC:jPh?=
Jurkat MoPvSpVv[3Srb36gRZN{[Xl? NV\TdJVpOTCvTR?= NUTD[ok{OWh? NYracZdr\GWlcnXhd4V{KHSqZTDlfJBz\XO|aX;uJI9nKEyFMz3JTUBidmRidHjlJIZwem2jdHnvckBw\iCjdYTvdIhi\2:|b33ldy=> MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh4NECzO{c,OjF6NkSwN|c9N2F-
HeLa  M3LMbmN6fG:2b4jpZ4l1gSCDc4PhfS=> NWLIPHJiOm2P M3zIUFI1cA>? MXrpcohq[mm2ZYOgeIhmKGO7dH;0c5hq[2m2eTDv[kB{cWyrYnnubY4hfG9iSHXMZUBk\Wyucz6= MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh5NUO4OUc,OjF6N{WzPFU9N2F-
PC12/TetOn NGjsXZBHfW6ldHnvckBCe3OjeR?= MkLFNE4yNzGvTR?= NWr1fHJtOTiq NFPTVJNt\WGmczD0c{DPuS2|eX6oW3QqKGGlY4XteYxifGmxbjygeI95cWOrdImsJIFv\CCxbHnnc41meiCob4LtZZRqd28EoB?= MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTlyNk[1PUc,OjF7ME[2OVk9N2F-
RMPI8226  NVq2d3Q2TnWwY4Tpc44hSXO|YYm= NE\tR|k2dU1? MmC5NYg> MkTVd5VxeHKnc4Pld{B1cGVibHX2[Ywhd2ZiYYX0c5Bp[We7IIXu[IVzKG63dILp[Y51KGSncHzleIlwdg>? M4[zXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOUG1OlIxLz5{MUmxOVYzODxxYU6=
MCF-7 M3K4VmZ2dmO2aX;uJGF{e2G7 M2C2N|ExdU1? NUnzZm1wPDiq MWjicI9kc3NiYYX0c5Bp[We7IHnu[JVk\WRiYomgZo9zfGW8b33pZi=> MmO3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7M{G5N|coRjJzOUOxPVM4RC:jPh?=
HBx  MXjBdI9xfG:|aYOgRZN{[Xl? Ml3XNVBuVQ>? NGjCb5Q1QGh? Ml:4SG1UVw>? M1zIbYlv[3KnYYPld{Bk\WyuIHTlZZRp MlfBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJyMkCwO|goRjJ{MEKwNFc5RC:jPh?=
Marc-145 MYjGeY5kfGmxbjDBd5NigQ>? MYW1cW0> M3P0O|EzNzJ2L{O2bC=> NVTnZ5VIemWmdXPld{B1cGViUGLSV3YhfGm2ZYLzJIFv\CC2aHWgdJJwfGWrbjDlfJBz\XO|aX;u NFrm[Gc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkGxPVkxOCd-MkKxNVk6ODB:L3G+
U937 NHHqfHpHfW6ldHnvckBCe3OjeR?= MXiycW0> NGraXFIyOmh? NGn3[mhl\WO{ZXHz[ZMhfGinIHH1eI9xcGGpeTDyZZRqd8Li MmrBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzNUWxOVAoRjJ{MUW1NVUxRC:jPh?=
BGC-823 NGG1cVhHfW6ldHnvckBCe3OjeR?= NX:1bIZCPW2P MlfnNog> M3;YZ4lvcGmkaYTzJJRp\SC{YYTlJI9nKGG3dH;wbIFocWNiY3XscJM> MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjN{MkG1Nkc,OjJ|MkKxOVI9N2F-
A549 NIfGbHVHfW6ldHnvckBCe3OjeR?= NIW0ZYkxNjGvTR?= M2W1e|I1cA>? Mnrhd5VxeHKnc4Pld{BUXTFzMke0MYlv\HWlZXSgZ4VtdCCmZXH0bC=> MlnMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2Nk[5OlAoRjJ{NE[2PVYxRC:jPh?=
pDCs MUTGeY5kfGmxbjDBd5NigQ>? NEjiXGgyOG2P NF7JZ5QxNjWq MYlCpJJm\HWlZYOgeIhmKGmwZIXjeIlwdiCxZjDJSm4u|rFiYomgd5NTVkF2MB?= Mm\5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ|OU[1PVkoRjJ{M{m2OVk6RC:jPh?=
HeLa  NEnMNFRCeG:ydH;zbZMhSXO|YYm= NH3iRWg2dU1? MVOyOIg> NUPsfJlNcW6mdXPld{Bk[XOyYYPlMYRmeGWwZHXueEBk\WyuIHTlZZRp M1\tRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUS1NVI5Lz5{MkW0OVEzQDxxYU6=
U251  M1XWWGFxd3C2b4Ppd{BCe3OjeR?= NYr1cpY5PW2P MUmyOIg> Mo\wbY5kemWjc3XzJHMyNWmwZIXj[YQh[2WubDDk[YF1cA>? M4PHPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUe5O|g5Lz5{MkW3PVc5QDxxYU6=
MCF-7  MlvzRZBweHSxc3nzJGF{e2G7 MnvkNE4ydU1? NF;QSI43cA>? NE\BbGJmdmijbnPld{B{cXK2aX7vcE1qdmS3Y3XkJIFxd3C2b4Ppdy=> MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjd3MUm4PUc,OjJ5NUG5PFk9N2F-
PC-3  Mo\nRZBweHSxc3nzJGF{e2G7 MXqycW0> MWeybC=> NULhNZVEcW6lcnXhd4V{KE:UST3pcoR2[2WmIHPlcIwh\GWjdHi= M4X4fVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{S1OVgxLz5{Mke0OVU5ODxxYU6=
HCT116 NGL4SWJCeG:ydH;zbZMhSXO|YYm= MnTLOY1O M4LxZVI1cA>? MXTEUXNQ M4qydoVvcGGwY3XzJIFxcWenbnnuMYlv\HWlZXSgZ4VtdCCmZXH0bC=> NHO0Oow9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NE[yOlUzOid-MkS2NlY2OjJ:L3G+
U2OS NHXCVm1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFznW|MyOG2P NUnL[3ZpOjSq M37TUolvfGWwc3nmbYV{KHSqZTDndo94fGhiaX7obYJqfGmxbjDpcoR2[2WmIHL5JGRwgA>? NE\iOI49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NE[zPVAyOyd-MkS2N|kxOTN:L3G+
A2780cp NIGy[YRCeG:ydH;zbZMhSXO|YYm= M2HiSlIvPW2P NWfuWmhZOWh? M2TkNoRlUDKR NIDDfYVmdmijbnPld{BkcXOybHH0bY4ucW6mdXPl[EBk\WyuIHTlZZRp MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDhzN{m0Okc,OjR6MUe5OFY9N2F-
HepG2 M1;Qc2Z2dmO2aX;uJGF{e2G7 NGPJRZg2dU1? NIDyWmY1cA>? NWW5TZhvcW6lcnXhd4V{KGOnbHz1cIFzKGyndnXsd{Bw\iCKTNMg NFTtSIo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEexN|U5Pyd-MkS3NVM2QDd:L3G+
Microglia  MkexRZBweHSxc3nzJGF{e2G7 MUO1cW0> MXmyOIg> NF\JNoVl\WO{ZXHz[ZMhcHmyb4jpZU1qdmS3Y3XkJINmdGxiZHXheIg> MlewQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6MUi2NFEoRjJ2OEG4OlAyRC:jPh?=
MDA-MB 231 M{G3eWFxd3C2b4Ppd{BCe3OjeR?= M3TIelVuVQ>? MXmwMlVp M3XCfY1w\HWuYYTld{BVd2OxbXnuxs7DqGmwZIXj[YQh[XCxcITvd4l{ M4nwPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OEOwO|gyLz5{NEizNFc5OTxxYU6=
PANC-1  M1r1VGFxd3C2b4Ppd{BCe3OjeR?= NW\HOVE4OW2P MojwOFhp MmfmSG1UVw>? MnfU[Y5p[W6lZYOgZo9zfGW8b33pZk1qdmS3Y3XkJINmdGxidnnhZoltcXS7IHzvd5M> NHK1U2k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEi0NlE2QCd-MkS4OFIyPTh:L3G+
MDA-MB-231 M2XMTmZ2dmO2aX;uJGF{e2G7 MoTFNo1O NH:2PJA1QGh? MXPwdo9ud3SnczDUUU1qdmS3Y3XkJINmdGxiZHXheIg> M2PMWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUewOlc3Lz5{NEm3NFY4PjxxYU6=
MDA-MB-231 NF:1R2NHfW6ldHnvckBCe3OjeR?= MUeycW0> Ml\DNlRp NEPxN3pqdmirYnn0d{BifXSxcHjh[5khcW6mdXPl[EBjgSCWTdMg MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl5ME[3Okc,OjR7N{C2O|Y9N2F-
MCF-7  M1;tdWZ2dmO2aX;uJGF{e2G7 NWGwUFg6Om2P NH\sNJA1QGh? MkL2dJJwdW:2ZYOgWG0ucW6mdXPl[EBk\WyuIHTlZZRp MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl5ME[3Okc,OjR7N{C2O|Y9N2F-
MCF-7  MnjySpVv[3Srb36gRZN{[Xl? MkXONo1O MWeyOIg> NHvwW4FqdmirYnn0d{BifXSxcHjh[5khcW6mdXPl[EBjgSCWTdMg M{THeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUewOlc3Lz5{NEm3NFY4PjxxYU6=
HepG2 MkjoRZBweHSxc3nzJGF{e2G7 NVT5R5N4O22P MWi1bC=> MoTZdoVlfWOnczDj[YxtKGGyb4D0c5NqeyCrbnT1Z4VlKGK7IGHEdy=> MlH3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6M{[1PVUoRjJ{OEO2OVk2RC:jPh?=
HeLa MUfBdI9xfG:|aYOgRZN{[Xl? MVqxNI1O MYOybC=> NXjo[ZhJ\GWlcnXhd4V{KGOnbHygeoli[mmuaYT5JINwNXS{ZXH0cYVvfCC5aYToJHBGUQ>? M4TqblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MECwNVM2Lz5{M{CwNFE{PTxxYU6=
SK-HEP-1 MY\BdI9xfG:|aYOgRZN{[Xl? NWDLVnpsOTCvTR?= MWSxbC=> MmDWdJJwfGWldIOgZYdicW6|dDDheZRweGijZ4mgZY5lKGmwZIXj[ZMh[XCxcITvd4l{KGmwIHL1[oFtcW5vdILlZZRm\CClZXzsdy=> NWSyeGFbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4OVg3PDlpPkKyPFU5PjR7PD;hQi=>
MDA-MB231 MYrGeY5kfGmxbjDBd5NigQ>? NYO4VlJpPW2P MlOyNYg> NFntfVhqdmO{ZXHz[ZMhemW|dnXyZZRzd2xvbXXkbYF1\WRiY3HzdIF{\SCjY4TpeoF1cW:wIHHu[EBk\WyuIHTlZZRp MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB6OEi1NEc,OjNyOEi4OVA9N2F-
PaCa44 M{jFWWFxd3C2b4Ppd{BCe3OjeR?= MWiyMlVuVQ>? MVuxbC=> NHz2R21z\WS3Y3XzxsBo\W6rcHnuMY1m\GmjdHXkJIFxd3C2b4Ppdy=> NXLBV4ViRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxNlQyOTJpPkKzNVI1OTF{PD;hQi=>
T-47D MW\GeY5kfGmxbjDBd5NigQ>? MnLENVBuVQ>? NX62d|FvOmh? NGfH[VNqdmirYnn0d{BifXSxcHjh[5kheHKxY3Xzd{BidmRiaX7jdoVie2W|IILhdIFugWOrbjDpcoR2[2WmIHHwc5B1d3Orcx?= MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzNyMECyOkc,OjN|MECwNlY9N2F-
GTL-16  NHH6[mJCeG:ydH;zbZMhSXO|YYm= M1jIflVuVQ>? M1j4d|I1cA>? MXPy[YR2[2W|IHPlcIwhfmmjYnnsbZR6KGG|IHPvcZBiemWmIITvJINmdGy|IITy[YF1\WRid3n0bEBOTVRiaX7obYJqfG:{cx?= MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzNzM{S5NEc,OjN|MUO0PVA9N2F-
U251MG  NUm3RpNmTnWwY4Tpc44hSXO|YYm= MojjN41O M3LxU|Fp NELZdlV{fXCycnXzd4V{KEyFMz3JTUBxem:2ZXnuJIV5eHKnc4Ppc44> NFfQb5k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{OzPFYyQCd-MkOzN|g3OTh:L3G+
T24 MV\GeY5kfGmxbjDBd5NigQ>? M2jNdFExdU1? M{jLdFFp Mn\kdoVlfWOnczD0bIUh[2ynYY\h[4Uhd2ZiTFOzJIFnfGW{IHLhbYNidGmwIITy[YF1dWWwdB?= NIraNYk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{O1OFA5OCd-MkOzOVQxQDB:L3G+
HUVECs MY\GeY5kfGmxbjDBd5NigQ>? NHOxOms{dU1? M2W0XVI1cA>? NFTzeJFjdG:la4OgeIhmKHC{b4TlZ5RqfmViZX\m[YN1KG:oIILld5ZmemG2cn;sJIJ6KGmwaHnibZRqdmdiYYX0c5Bp[We7 MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzN3OEmyPEc,OjN|NUi5Nlg9N2F-
MCF-7  M3O4bmZ2dmO2aX;uJGF{e2G7 MnexOY1O NFy5ZlIzPGh? MmDpbY5pcWKrdIOgd5Rien[jdHnvck1qdmS3Y3XkJIF2fG:yaHHnfS=> NIq4TWc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{O5OVY4QSd-MkOzPVU3Pzl:L3G+
Hela  M2rmNWZ2dmO2aX;uJGF{e2G7 NHTvW|A2dU1? NIT0[3AzPGh? NV;mbo0ycW6qaXLpeJMhe3Sjco\heIlwdi2rbnT1Z4VlKGG3dH;wbIFogQ>? MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzN7NU[3PUc,OjN|OUW2O|k9N2F-
OR6 MoTlSpVv[3Srb36gRZN{[Xl? M1e1O|ExdU1? NXjDNnA4PzKq MVnzeZBxemW|c3XzJGhEXiC{ZYDsbYNifGmxbjDhcoQh\m:{bXH0bY9vKG:oIHH1eI9xcGGpb4PvcYV{ MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzN7NUi3OUc,OjN|OUW4O|U9N2F-
HT-29  NEDrUJhHfW6ldHnvckBCe3OjeR?= NXTQVoN{OW2P MmLxOFgwQT[q MoDRbY5pcWKrdIOgRW1RUyCrbnT1Z4V{KGG3dH;wbIFocWNiY3XscEBl\WG2aB?= M2ju[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUC4NlczLz5{M{WwPFI4OjxxYU6=
SH-SY5Y MofHR5l1d3SxeHnjbZR6KEG|c3H5 MWW1cW0> Mk\pNlRp NGm4fVdqdmO{ZXHz[ZMhWEOQIITvfIlkcXS7 NG\VS3g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{WyOVI3PSd-MkO1NlUzPjV:L3G+
Saos-2  NInsc|JCeG:ydH;zbZMhSXO|YYm= M17NXFFuVQ>? M1m5UVk3cA>? NUnod3pTcW6lcnXhd4V{KGOnbHyg[IVifGhiaX7keYNm\CCkeTDQR3g> NHfpUVk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{W2N|E4OSd-MkO1OlMyPzF:L3G+
1321N1 MoP1R5l1d3SxeHnjbZR6KEG|c3H5 NEL4NnQ2dU1? NW[xWHgyOjSq M3vGNpBzd3SnY4TzJINmdGxiYXfhbY5{fCCSQ16tbY5lfWOnZDD0c5hq[2m2eR?= MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzV{NUK2OUc,OjN3MkWyOlU9N2F-
A2780 MXXBdI9xfG:|aYOgRZN{[Xl? MnHMOY1O NYrsO|V4OjSq MUfjc453\XK2czDGWHk4OjBid3n0bEBETESSIHnueI8h[W5iYXTkbZRqfmViZX\m[YN1KHSxd3Hy[JMhc2mubHnu[{BwfmG{aXHuJINidmOncjDj[Yxtew>? NVvZVplXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1PVIzQDFpPkKzOVkzOjhzPD;hQi=>
OV2008 M{P4XGFxd3C2b4Ppd{BCe3OjeR?= MojUOY1O MoTINlRp MmLKZ49vfmW{dIOgSnR[PzJyIIfpeIghS0SGUDDpcpRwKGGwIHHk[Il1cX[nIHXm[oVkfCC2b4fhdoR{KGurbHzpcochd3[jcnnhckBk[W6lZYKgZ4VtdHN? M3S0TVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUmyNlgyLz5{M{W5NlI5OTxxYU6=
PC12  Mom2SpVv[3Srb36gRZN{[Xl? NEXjXm8yOG2P NE\TbGYzPGh? Mnn4e4F1\XJ? MUhCpIlvcGmkaYTzJINpgW2xdIL5dJNqdi2uaXvlJJBzd3SnYYPvcYFtKGGldHn2bZR6Ng>? M{\pNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkCzPVc6Lz5{M{[wN|k4QTxxYU6=
SH-SY5Y M3zkb2Fxd3C2b4Ppd{BCe3OjeR?= NH\NeFQ2dU1? MnHtNYg> Mof2ZYJwdGm|aHXzJINmdGG|dILvcEBv\XW{b4Dyc5Rm[3SrdnWg[YZn\WO2 MlrXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4MUmzPVUoRjJ|NkG5N|k2RC:jPh?=
SH-SY5Y MWDGeY5kfGmxbjDBd5NigQ>? NFzaVWkydU1? MW[yOIg> NUjSU|VZcW6qaXLpeJMhfGinIHH1eI9xcGGpeTDpcoR2[2WmIHL5JHRQS1B? MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzd2M{G0PEc,OjN5NEOxOFg9N2F-
HepG2 NH2xc2JHfW6ldHnvckBCe3OjeR?= MYWxNI1O MVWyOIg> M37oNYlvcGmkaYTzJJNqXEmJQWKtJIFv\CCKQmPTMYlv\HWlZXSgZZV1d3CqYXf5 MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzhzN{C0NEc,OjN6MUewOFA9N2F-
HeLa NHPvbYtHfW6ldHnvckBCe3OjeR?= MVGxNI1O NVzlZmhGOmh? MoTId5VxeHKnc4Pld{BNSzNiSVmg[ZhxemW|c3nzc44> NYXQ[VBWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4OlQ4OzhpPkKzPFY1PzN6PD;hQi=>
HONE-1  MVLGeY5kfGmxbjDBd5NigQ>? NUjrNY1qPW2P M2\tUVFp NWnydIdXemWycnXzd4V{KD[{LX3l[IlifGWmIGLPV{Bxem:mdXP0bY9v M2DLXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEmyN|U5Lz5{M{i5NlM2QDxxYU6=
MCF7 NFu4epdHfW6ldHnvckBCe3OjeR?= NUfTcpZUPW2P NF7yV5MzPGh? M1rlUIlv[3KnYYPld{BEfU9iaX7keYNm\CClZXzsJIRm[XSq M{nPSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OU[yOlI6Lz5{M{m2NlYzQTxxYU6=
HO8910 NXjlRXJsSXCxcITvd4l{KEG|c3H5 MWexNI1O NUTWXHJHOTKq M3fDb4VvcGGwY3XzJGIyQS2rbnT1Z4VlKGGyb4D0c5Nq M1zQUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OUizOlExLz5{M{m4N|YyODxxYU6=
SMMC-7721 Ml\yRZBweHSxc3nzJGF{e2G7 MVu1cW0> MoPGNlRp MkXDZZR1\W63YYTld{BVVkZvzsGgdJJwfGWldHnvckBi\2GrboP0JJNmenWvIIP0ZZJ3[XSrb36tcYVlcWG2ZXSgZZBweHSxc3nz MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDB4Nk[5N{c,OjRyNk[2PVM9N2F-
Hep3B NF[wVIdCeG:ydH;zbZMhSXO|YYm= NX65W5VlPW2P MX2yOIg> MXXheJRmdnWjdHXzJHRPTi4QsTDwdo91\WO2aX;uJIFo[Wmwc4Sgd4VzfW1ic4ThdpZifGmxbj3t[YRq[XSnZDDhdI9xfG:|aYO= NYPGWWp[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwOlY3QTNpPkK0NFY3Pjl|PD;hQi=>
H460 NUfZOI16TnWwY4Tpc44hSXO|YYm= MnTvNVBuVQ>? NGqwdI41cA>? NFPPNphqdmO{ZXHz[ZMh[2m|cHzheIlvNWmwZIXj[YQh[2WubDDk[YF1cA>? NWjwT3RTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSxO|MzODhpPkK0NVc{OjB6PD;hQi=>
A549 MoS3SpVv[3Srb36gRZN{[Xl? M4nlc|ExdU1? M4TZZVRp NYjvZVlJcW6qaXLpeJMh[XW2b4DoZYd6KGmwZIXj[YQh[nliaYLyZYRq[XSrb36= M4Owb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MUSyO|M2Lz5{NEG0Nlc{PTxxYU6=
H1299  NETRTXFHfW6ldHnvckBCe3OjeR?= NIrsOYgyOG2P NIfyWow1cA>? MV3pcoNz\WG|ZYOgZ4l{eGyjdHnuMYlv\HWlZXSgZ4VtdCCmZXH0bC=> NHLPUFI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEG3N|IxQCd-MkSxO|MzODh:L3G+
WiDr M4Lsd2Z2dmO2aX;uJGF{e2G7 NFqwR5oyOG2P NWT6W4N5OWh? NVjndmp3cW6qaXLpeJMhWEOETD3pcoR2[2WmIFzDN{BKUSCneIDy[ZN{cW:w NYLjXYdyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSxPVA1QDlpPkK0NVkxPDh7PD;hQi=>
LoVo  M164e2Fxd3C2b4Ppd{BCe3OjeR?= M4P6c|VuVQ>? NGKwSIU1QGh? NFPnV2RmdmijbnPld{BFS0FvaX7keYNm\CCjcH;weI9{cXNw MlL2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR{MEG4NVIoRjJ2MkCxPFEzRC:jPh?=
HepG2 E47 MnXBSpVv[3Srb36gRZN{[Xl? NH3iUo8zNjWvTR?= M{\HbVQ5cA>? MYTpcoNz\WG|ZYOgeIhmKHSxeHnjbZR6KG:oIFHBMEBDW09uIHHu[EBES2x2 MlvlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR{N{O3N|goRjJ2MkezO|M5RC:jPh?=
RKO MXnGeY5kfGmxbjDBd5NigQ>? NUTofpNSOm2P NXPWS4R[OWh? MnLzSG1UVw>? M1zuVYVvcGGwY3XzJINmdGxiZHXheIgh[nliZ3Xs[IFv[W27Y3nu NH3xZlg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEK5NVc4Pyd-MkSyPVE4Pzd:L3G+
Hep3B NHj1[VdCeG:ydH;zbZMhSXO|YYm= M4nLbFJuVQ>? NFyye4EyOmh? NF3MOnFFVVOR NYX0c4lycW6qaXLpeJMhSVqGOEC1OU1qdmS3Y3XkJINmdGxiZHXheIg> M2XZd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2Mkm3N|AxLz5{NEK5O|MxODxxYU6=
ACHN-5968 MYXBdI9xfG:|aYOgRZN{[Xl? MVO1cW0> MYGzbC=> M2DB[IVvcGGwY3XzJJBi[2yrdHH4[YwudWWmaXH0[YQh[XCxcITvd4l{yqB? MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDNyNU[wOEc,OjR|MEW2NFQ9N2F-
Huh7 M1LvcmFxd3C2b4Ppd{BCe3OjeR?= MWSycW0> NVjEfINGOTKq MVvEUXNQ Mo\vbY5pcWKrdIOgRXpFQDB3NT3pcoR2[2WmIHPlcIwh\GWjdHi= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDJ7N{OwNEc,OjR{OUezNFA9N2F-
UOK257 M1W4WmFxd3C2b4Ppd{BCe3OjeR?= M{GxVlVuVQ>? MXKzbC=> M4G1boVvcGGwY3XzJJBi[2yrdHH4[YwudWWmaXH0[YQh[XCxcITvd4l{yqB? MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDNyNU[wOEc,OjR|MEW2NFQ9N2F-
ECSCs  M1XmNmFxd3C2b4Ppd{BCe3OjeR?= NEG4TWIyOG2P Mkm4OIg> NEfYOVFl\WO{ZXHz[ZMhemGyYX35Z4lvNXS{ZXH0[YQh[XCxcITvd4l{ MnPKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR|MUmxNFkoRjJ2M{G5NVA6RC:jPh?=
MCF-7  Mn;VSpVv[3Srb36gRZN{[Xl? MU[xNI1O NGfVWVgzPGh? NV65Nnd{cW6qaXLpeJMhfGinIHH1eI9xcGGpeTDpcoR2[2WmIHL5JINp\W2xdHjldoFxgSCmcoXndy=> M1vnN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{G1OVc5Lz5{NEOxOVU4QDxxYU6=
SGC-7901  NWD3T3dNSXCxcITvd4l{KEG|c3H5 NIrRWJUzdU1? NGHIR2wycA>? MXLpcoNz\WG|ZYOgR2EuPCCrbnT1Z4VlKGGyb4D0c5Nqew>? MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN{MUO0NEc,OjR|MkGzOFA9N2F-
SMMC-7721 MW\BdI9xfG:|aYOgRZN{[Xl? MYCycW0> NW\SZldSOWh? MVvpcoNz\WG|ZYOgR2EuPCCrbnT1Z4VlKGGyb4D0c5Nqew>? M3rzU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2M{KxN|QxLz5{NEOyNVM1ODxxYU6=
T24 MkDjRZBweHSxc3nzJGF{e2G7 NHv5eYk2dU1? M3\wSlEvPWh? NV;t[YtTeG:2ZX70bYF1\XNiY3Xs[YNwgGmkLXnu[JVk\WRiYYDvdJRwe2m| Mki5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR|NEmxO|YoRjJ2M{S5NVc3RC:jPh?=
NTUB1 MlfBRZBweHSxc3nzJGF{e2G7 M1;pRVVuVQ>? MkG0NU42cA>? NF\4UYdxd3SnboTpZZRmeyClZXzlZ495cWJvaX7keYNm\CCjcH;weI9{cXN? MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN2OUG3Okc,OjR|NEmxO|Y9N2F-
MG-63 MnewRZBweHSxc3nzJGF{e2G7 NWG0RotnOTCvTR?= NVjtUlJiOTKq NXP6TGZw\W6qYX7j[ZMhTFBvaX7keYNm\CCjcH;weI9{cXN? NITS[II9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEO1PFMxOSd-MkSzOVg{ODF:L3G+
MG-63 M4rpSWFxd3C2b4Ppd{BCe3OjeR?= NXixbm5WOC53L{HtUS=> M2jmWlMzcA>? NVvO[nlG\W6qYX7j[ZMhe2GuaX7vcZlkcW5vaX7keYNm\CClZXzsJIFxd3C2b4Ppdy=> MoPmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR|NUizOFIoRjJ2M{W4N|QzRC:jPh?=
MG-63 M2e5TWZ2dmO2aX;uJGF{e2G7 MXOwMlUwOW2P NGD4WVk1QGh? M3Hn[olv\HWlZYOgd4FtcW6xbYnjbY4ucW6mdXPl[EBk\WyuII\pZYJqdGm2eTDsc5N{ NXry[IlbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSzOVg{PDJpPkK0N|U5OzR{PD;hQi=>
U2OS  MVvGeY5kfGmxbjDBd5NigQ>? MYqwMlUwOW2P NFXGXWk1QGh? MmntbY5lfWOnczDzZYxqdm:veXPpck1qdmS3Y3XkJINmdGxidnnhZoltcXS7IHzvd5M> MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDN3OEO0Nkc,OjR|NUizOFI9N2F-
HGC-27 NWLBSXdsTnWwY4Tpc44hSXO|YYm= MUmxNI1O MUSxbC=> NWLKdVIycW6qaXLpeJMhfGinIHPlcIwhfmmjYnnsbZR6KGyxc4OgZpkhWkGGMECxJI9zKE2NLUKyNFY> NUPp[3EzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS0NVY{PDlpPkK0OFE3OzR7PD;hQi=>
HCT116  MnvNRZBweHSxc3nzJGF{e2G7 NFHTTpY2dU1? NYCyepo6OjSq NHzoR5ZmdmijbnPld{B1cGViYYDvdJRwe2m|IHnu[JVk\WRiYomgZZBq\2WwaX6= MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDZ{NkWyNkc,OjR4Mk[1NlI9N2F-
A549 NGDwSHhCeG:ydH;zbZMhSXO|YYm= NG\1eJMyOG2P MmnvOFhp MUXhZ4NmdGW{YYTld{B1cGVicnXkeYN1cW:wIH;mJINmdGxidnnhZoltcXS7IHnu[JVk\WRiYomgVHRZ MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDZ{NkeyNkc,OjR4Mk[3NlI9N2F-
Saos-2 NX7ZPWlWSXCxcITvd4l{KEG|c3H5 NX3iN4VkOTCvTR?= M3XFVVI1cA>? MVjpcpRmdnOrZnnld{B1cGViZ4Lve5RpKGmwaHnibZRqd25ib3[geIhmKFV{T2OgZ4VtdHNiaX7keYNm\CCkeTDEc5g> NVTNZ|V6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS2N|kxOTNpPkK0OlM6ODF|PD;hQi=>
U2OS MVXBdI9xfG:|aYOgRZN{[Xl? M4LSUlExdU1? Mn\vNlRp MmXrbY51\W6|aX\p[ZMhfGinIHfyc5d1cCCrbnjpZol1cW:wIH;mJJRp\SCXMl;TJINmdGy|IHnu[JVk\WRiYomgSI95 M{TKUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2NkO5NFE{Lz5{NE[zPVAyOzxxYU6=
HepG2 MWDGeY5kfGmxbjDBd5NigQ>? NHrwOVA2dU1? MYC0bC=> MXnpcoNz\WG|ZYOgTGwhemWuZXHz[S=> M3LB[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{GzOVg4Lz5{NEexN|U5PzxxYU6=
A549 M1e3NWFxd3C2b4Ppd{BCe3OjeR?= Mli0OY1O NYHPXGxKPDiq M4jt[4Rm[3KnYYPld{B1cGVicHXyZ4VvfGGpZTDv[kBk\WyuIHTlZZRpKGGwZDDlfJBz\XO|aX;uJIxmfmWuczDv[kBk[XOyYYPlMVMtKEKnY3zpck0yKGGwZDDMR|MuUUl? NIfvfFA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEewOlMxOyd-MkS3NFY{ODN:L3G+
A2780cp MX;BdI9xfG:|aYOgRZN{[Xl? NFfGRVQzNjWvTR?= M3e4bFFp NFficHZl\Eh{Tx?= MVLlcohidmOnczDjbZNxdGG2aX6tbY5lfWOnZDDj[YxtKGSnYYTo Ml;xQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6MUe5OFYoRjJ2OEG3PVQ3RC:jPh?=
Microglia  NVT3OmV{SXCxcITvd4l{KEG|c3H5 MnjZOY1O MWGyOIg> MoLN[IVkemWjc3XzJIh6eG:6aXGtbY5lfWOnZDDj[YxtKGSnYYTo MmDmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6MUi2NFEoRjJ2OEG4OlAyRC:jPh?=
HT-29  MYPBdI9xfG:|aYOgRZN{[Xl? MlraNY1O MnvlOFhp NVzWb2JvTE2VTx?= NF[xT5VmdmijbnPld{Bjd3K2ZYrvcYljNWmwZIXj[YQh[2WubDD2bYFjcWyrdImgcI9{ew>? NU\BdWVnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS4OFIyPThpPkK0PFQzOTV6PD;hQi=>
MDR MYPBdI9xfG:|aYOgRZN{[Xl? NXPZUWd1OTCvTR?= MXe2bC=> M1\2e5N1emWwZ4To[Y5{KHSqZTDwc5dmeiCxZjDhcpRq[2GwY3XyJIRzfWe| NGHnOVU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUCxPVcxOSd-MkWwNVk4ODF:L3G+
H157 NYHUVlFKTnWwY4Tpc44hSXO|YYm= MmD5OY1O MXmybC=> M2\XRZN2eHC{ZYPz[ZMhW1CFIHnu[JVk\WRiYXPjeY12dGG2aX;uJI9nKEyFMz3JTS=> MlzkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV{OEW2NlgoRjJ3Mki1OlI5RC:jPh?=
A549  MVXGeY5kfGmxbjDBd5NigQ>? M3vwR|VuVQ>? MVSybC=> NUPxPVNie3WycILld5NmeyCVUFOgbY5lfWOnZDDhZ4N2dXWuYYTpc44hd2ZiTFOzMWlK M{TJcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3Mki1OlI5Lz5{NUK4OVYzQDxxYU6=
A2780cp  Mo\iS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1jTS|FuVQ>? MlrwNYg> NVrsSHNycW6lcnXhd4V{KGOrc4DsZZRqdi2rbnT1Z4VlKGOnbHyg[IVifGh? NHfhZWU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUOyNlY6PCd-MkWzNlI3QTR:L3G+
NBL-W-S  NF[wOGNCeG:ydH;zbZMhSXO|YYm= MofkNY1O NFTMbYI3cA>? NW\6NZV1cW6lcnXhd4V{KGOnbHygZZBweHSxc3nzJIlv\HWlZXSgZpkhT0GQVD22NS=> M3\aWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3M{KzNlIzLz5{NUOyN|IzOjxxYU6=
NBL-W-S  NH7WfnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NIfoeJYydU1? NV;nZZUxPmh? NHLLZplmdmijbnPld{BISU6WLU[xJJRwgGmlaYT5 NWPHNZJrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWzNlMzOjJpPkK1N|I{OjJ{PD;hQi=>
A549  M2P4XGFxd3C2b4Ppd{BCe3OjeR?= NICzVXc2dU1? M1n6OVJp MmX1SG1UVw>? NGXNZmtqdmirYnn0d{BDTE2FLXnu[JVk\WRiYYDvdJRwfGmlIHPlcIwh\GWjdHi= NIXZOoU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUexOlU3OSd-MkW3NVY2PjF:L3G+
95D MkO5RZBweHSxc3nzJGF{e2G7 NV61N4sxPW2P MWKybC=> NVnVNJN5TE2VTx?= MWfpcohq[mm2czDCSG1ENWmwZIXj[YQh[XCxcITveIlkKGOnbHyg[IVifGh? NWPvSW9ORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW3NVY2PjFpPkK1O|E3PTZzPD;hQi=>
A549  MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFfNZ2w{dU1? MkG1Nog> M3HCcWROW09? M1T5S5Jm\HWlZYOg[5Jwf3SqIHnubIljcXSxcomg[YZn\WO2IH;mJGJFVUN? NV[yZ4RFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW3NVY2PjFpPkK1O|E3PTZzPD;hQi=>
95D NYTwRplZT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3;0dVNuVQ>? MVyybC=> NVPJRpZyTE2VTx?=