Tubastatin A HCl

製品コードS2627

Tubastatin A HCl化学構造

分子量(MW):371.86

Tubastatin A HCl is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more).

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カスタマーフィードバック(3)

  • Control and MEC17 KD macrophages (RAW264.7) were treated with TBSA or DMSO for 12 hours followed by LPS treatment for indicated time. p38 phosphorylation were determined by immuno-blotting.

    Nat Commun 2014 5, 3479. Tubastatin A HCl purchased from Selleck.

    Tubastatin A gefitinib-induced apoptosis in NSCLC cells via activation of AKT. H358 cells were treated as described in Figure 4. Representative immunoblots of cleaved caspase-3, AKT and ERK1/2 and of their respective phosphorylated forms are shown. Actin was used as a protein-level control.

    Int J Cancer 2014 134(11):2560-71. Tubastatin A HCl purchased from Selleck.

  • GH cells were treated with 0.5 μM TSA or the DMSO solvent as indicated. Subsequently, Chromatin immunoprecipitation (ChIP) was performed with antibodies to NF-YB or a pre-immune control antibody. The DNA corresponding to the indicated promoters was quantified by real-time PCR and displayed in relation to the amount of input DNA. Bars indicate the standard error from three independent experiments.

    Oncotarget, 2016, 7(23):33484-97. Tubastatin A HCl purchased from Selleck.

製品安全説明書

HDAC阻害剤の選択性比較

生物活性

製品説明 Tubastatin A HCl is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more).
ターゲット
HDAC6 [1]
(Cell-free assay)
HDAC8 [1]
(Cell-free assay)
15 nM 854 nM
体外試験

Tubastatin A is substantially selective for all 11 HDAC isoforms and maintains over 1000-fold selectivity against all isoforms excluding HDAC8, where it has approximately 57-fold selectivity. In homocysteic acid (HCA) induced neurodegeneration assays, Tubastatin A displays dose-dependent protection against HCA-induced neuronal cell death starting at 5 μM with near complete protection at 10 μM. [1] At 100 ng/mL Tubastatin A increases Foxp3+ T-regulatory cells (Tregs) suppression of T cell proliferation in vitro. [2] Tubastatin A treatment in C2C12 cells would lead to myotube formation impairment when alpha-tubulin is hyperacetylated early in the myogenic process; however, myotube elongation occurs when alpha-tubulin is hyeperacetylated in myotubes. [3] A recent study indicates that Tubastatin A treatment increases cell elasticity as revealed by atomic force microscopy (AFM) tests without exerting drastic changes to the actin microfilament or microtubule networks in mouse ovarian cancer cell lines, MOSE-E and MOSE-L. [4]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
neuron cultures M3vxVWtqdmG|ZTDhd5NigQ>? MWWyMlUh|ryP NH\i[WpFVVOR NFf1[HRqdmS3Y3XzJO6yNXS3YoXsbY4hcHmyZYLhZ4V1gWyjdHnvci=> M{Lp[FIxPjF2OUO2
neuron cultures M4DtZWZ2dmO2aX;uJIF{e2G7 MorxglExKM7:TR?= M3fJVWROW09? M3i1fZBzd3SnY4TzJIFo[Wmwc4Sg[4x2fGG2aHnvcoUh\GWybHX0bY9vNWmwZIXj[YQhd3irZHH0bZZmKHO2cnXzdy=> NWO5T|B3OjB4MUS5N|Y>
134/04 NVi0WJpkTnWwY4Tpc44h[XO|YYm= NE\Jdmo4NjViwsXN MXnpcZBicXK|IH35c5R2[mViZn;ycYF1cW:w NXrZW|dxOjJzN{S4N|k>
C2C12 NGHZdHlHfW6ldHnvckBie3OjeR?= NFfQUGo4NjViwsXN M1;QfolueGGrcoOgcZlwfHWkZTDmc5Ju[XSrb36= NWfSTFlbOjJzN{S4N|k>
HaCaT keratinocytes MofqSpVv[3Srb36gZZN{[Xl? Mmf0NVAh|ryP MnXiZoxw[2u|IHHyd4VvcXSnIH\yc40hcW6mdXPpcochVnKoMjDwdo91\WmwIITyZY5{dGG2aX;u MUeyNlM3PzZ6OR?=
JURL-MK1 MkjXSpVv[3Srb36gZZN{[Xl? NXHp[mloOTBizszN NV\BR2Mx\W6qYX7j[ZMh[2WubDDh[Ihme2m4aYT5JJRwKG[rYoLvcoVkfGmw M4GwdlI{ODJ{NUiz
CML-T1 NIjDOXZHfW6ldHnvckBie3OjeR?= NHLpcVUyOCEQvF2= NWL6eXk2\W6qYX7j[ZMh[2WubDDh[Ihme2m4aYT5JJRwKG[rYoLvcoVkfGmw M4PuW|I{ODJ{NUiz
K562 Mni0SpVv[3Srb36gZZN{[Xl? NXvtb2w5OTBizszN MlHV[Y5p[W6lZYOgZ4VtdCCjZHjld4l3cXS7IITvJIZq[nKxbnXjeIlv MV2yN|AzOjV6Mx?=
HL-60 MoHLSpVv[3Srb36gZZN{[Xl? NG\NcHkyOCEQvF2= NY\kcJZE\W6qYX7j[ZMh[2WubDDh[Ihme2m4aYT5JJRwKG[rYoLvcoVkfGmw NHvySZEzOzB{MkW4Ny=>
KMCH MWrHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NUjJ[I9nhjFyIN88US=> MmHV[IVkemWjc3XzJJBzd2yrZnXyZZRqd25iYX7kJIFv[2ixcnHn[U1qdmSncHXu[IVvfCCpcn;3eIg> MlH5NlM{PzB|Mke=
THP-1 NVj0VFhoTnWwY4Tpc44h[XO|YYm= MnfRglExKM7:TR?= MW\pcohq[mm2czDUUmYu|rFiYX7kJGlNNTZic3XjdoV1cW:w NWHldVRKOjN3NEG2N|Q>
RAW 264.7 MV7GeY5kfGmxbjDhd5NigQ>? NV7UcnY6hjFyIN88US=> MVXheJRmdnWjdHXzJG5QKHC{b3T1Z5Rqd25? MmDJNlM2PDF4M{S=
HT3 MkPkSpVv[3Srb36gZZN{[Xl? NV;Dd4d1hjVizszN NUHyWmNmTE2VTx?= MYPpcoR2[2W|IITo[UBlcW[oZYLlcpRq[WxizsGteJVjfWyrbjDhZ4V1gWyjdHnvci=> NITUfIszOzZ7OES2PC=>
SiHa MmnYSpVv[3Srb36gZZN{[Xl? M1XhRZ42KM7:TR?= MWfEUXNQ M1jKR4lv\HWlZYOgeIhmKGSrZn\ldoVvfGmjbDFOtU11fWK3bHnuJIFk\XS7bHH0bY9v NGOyNJUzOzZ7OES2PC=>
CaSki M2TnN2Z2dmO2aX;uJIF{e2G7 Ml3EglUh|ryP MUHEUXNQ MXTpcoR2[2W|IITo[UBlcW[oZYLlcpRq[WxizsGteJVjfWyrbjDhZ4V1gWyjdHnvci=> NIG5N20zOzZ7OES2PC=>
SiHa NFXZUnpHfW6ldHnvckBie3OjeR?= NW\2PY5VhjVizszN MXHEUXNQ MmHWbY5pcWKrdIOgWIhieHOrZ3Hy[4lvNSCxcjDFS2YucW6mdXPl[EBUV0OHIHHjeIl3[XSrb36= Ml;MNlM3QTh2Nki=
CaSki MWLGeY5kfGmxbjDhd5NigQ>? NIPtbWh,PSEQvF2= MlLCSG1UVw>? NXT3V4ZkcW6qaXLpeJMhXGijcIPp[4Fz\2mwLTDvdkBGT0ZvaX7keYNm\CCVT1PFJIFkfGm4YYTpc44> NFnNUFYzOzZ7OES2PC=>
MCF-7 MWnHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NX;OblRVOzBizszN NGHZNZVFVVOR NWfPXmNqUUN3ME2xOUDPxE1? M2jHcVI{Pzl6Nkiw
MCF-7 MmfKSpVv[3Srb36gZZN{[Xl? M4mwVFMxKM7:TR?= NFXOdYtFVVOR MnOxbY5kemWjc3XzJJRp\SCvaXPyc5R2[nWuZTDhZ4V1gWyjdHnvckBt\X[nbD6= MU[yN|c6QDZ6MB?=
MCF-7 MV;GeY5kfGmxbjDhd5NigQ>? MXezNEDPxE1? M{jGTmROW09? M{\j[pN1[WKrbHn6[ZMhdWmlcn;0eYJ2dGW|IHHnZYlve3RiY3;s[E1qdmS3Y3XkJIRmeG:ueX3ldol7[XSrb36= NHLtR2MzOzd7OE[4NC=>
MCF-7 Mn71SpVv[3Srb36gZZN{[Xl? MXOxOUDPxE1? Mly4SG1UVw>? MVLzeIFjcWyrenXzJI1q[3KxdIXieYxmeyCjZ3HpcpN1KG6xY3;kZZpwdGVvaX7keYNm\CCmaYPhd5NmdWKueR?= MoW3NlM4QTh4OEC=
MCF-7 NFvFfXNHfW6ldHnvckBie3OjeR?= M3Tyc|MxKM7:TR?= NHu1[FBFVVOR MkXxZYx1\XKnczD0bIUh[XO|ZX3icJkh\HmwYX3pZ5Mhd2ZiaX70[ZJxcGG|ZTDtbYNzd3S3YoXs[ZM> MWKyN|c6QDZ6MB?=
MCF-7 NF7iOFdHfW6ldHnvckBie3OjeR?= NYPwTHI3OzBizszN NH\xW|NFVVOR NHPtclBqdmO{ZXHz[ZMhfGinIHLpcoRqdmdib3[gTGRCSzZid3n0bEBqdnSncoDoZZNmKG2rY4LveJVjfWyncx?= MWmyN|c6QDZ6MB?=
PC12 MYTGeY5kfGmxbjDhd5NigQ>? NGPEXWp,OyEQvF2= NGDSe3hFVVOR MmfaeZAuemWpdXzheIV{KGGwdHmtc5hq\GG2aY\lJIdmdmViZYjwdoV{e2mxbjDy[YxifGWmIITvJJRz[W6|Y4LpdJRqd25iZnHjeI9zKFiEUEHz M1GwO|I1QTB7Nki2
PC12 MlvWS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MVj+N{DPxE1? MXXEUXNQ Ml;DdoV3\XK|ZTDINm8zNWmwZIXj[YQh\3Kxd4ToJIlvcGmkaYTpc44> M4nz[lI1QTB7Nki2
HEK293T M2PHNGZ2dmO2aX;uJIF{e2G7 MWX+N{DPxE1? MmXqSG1UVw>? NVfKcXp6fXBvcnXneYxifGWmIGjCVFF{KHC{b4TlbY4hdGW4ZXy= NInMZ3ozPDlyOU[4Oi=>
HEK293T NV3pUFEzTnWwY4Tpc44h[XO|YYm= MoHmglMh|ryP M3\jU2ROW09? NYP5R5lo\GWuYYnzJHhDWDG|IIDyc5RmcW5iZHXndoFl[XSrb36geoliKGGlZYT5cIF1cW:wLX3l[IlifGWmIIDyc5Rm[XOxbXHsJIRm\3KjZHH0bY9v NYHH[5NlOjR7MEm2PFY>
Huh7 MV7GeY5kfGmxbjDhd5NigQ>? MXj+OUDPxE1? MXXEUXNQ Mojmd5VxeHKnc4Pld{Bxem:uaX\ldoF1cW:wIH;mJIhmeGG2aYTpd{BEKH[rcoXzJJJmeGyrY3;uJJdqfGhiRVO1NEA:KDBwMzFOwG0> NEfi[VIzPTFyOEOyOi=>
SKMEL21 MWjHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? MWL+OVAxKG6P NFnocmFFVVOR M1G1WYlvcGmkaYTzJINmdGxicILvcIln\XKjdHnvci=> MofkNlU6PTd6MUK=
SKMEL103 MkO0S5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MlTWglUxOCCwTR?= M1HETGROW09? NV20[YNrcW6qaXLpeJMh[2WubDDwdo9tcW[ncnH0bY9v M2nUcFI2QTV5OEGy
SKMEL28 MWLHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NX\U[3A{hjVyMDDuUS=> NGLQXGNFVVOR MmSzbY5pcWKrdIOgZ4VtdCCycn;sbYZmemG2aX;u NXzlSFVNOjV7NUe4NVI>
WM164 NHTxV21Iem:5dHigbY5pcWKrdH;yfUBie3OjeR?= NV\z[oF{hjVyMDDuUS=> M1LtXmROW09? NFPwN4ZqdmirYnn0d{Bk\WyuIIDyc4xq\mW{YYTpc44> NHvxTXczPTl3N{ixNi=>
WM1361a MofRS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? NIPzV4h,PTByIH7N M2nDR2ROW09? M2e0[olvcGmkaYTzJINmdGxicILvcIln\XKjdHnvci=> NFfoeY0zPTl3N{ixNi=>
WM1366 MXLHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NF24W5h,PTByIH7N M1rHWWROW09? M4PkfIlvcGmkaYTzJINmdGxicILvcIln\XKjdHnvci=> MX:yOVk2PzhzMh?=
WM793 MoXiS5Jwf3SqIHnubIljcXSxcomgZZN{[Xl? MmS4glUxOCCwTR?= NEDPTXpFVVOR NHqzNGdqdmirYnn0d{Bk\WyuIIDyc4xq\mW{YYTpc44> MXuyOVk2PzhzMh?=
WM35 NGnnW|JIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= NWrQZYpShjVyMDDuUS=> NHTMUmJFVVOR M2jTT4lvcGmkaYTzJINmdGxicILvcIln\XKjdHnvci=> NWHnWlljOjV7NUe4NVI>
WM983a MUPHdo94fGhiaX7obYJqfG:{eTDhd5NigQ>? NFHIVmh,PTByIH7N NXP6VnpZTE2VTx?= MVfpcohq[mm2czDj[YxtKHC{b3zp[oVz[XSrb36= M1\tclI2QTV5OEGy
WM793 NX6xToRZTnWwY4Tpc44h[XO|YYm= MYj+OkDPxE1? Mn7TSG1UVw>? NYfrfnF4cW6mdXPlJGcyKGG{cnXzeC=> M163[|I2QTV5OEGy
WM164 MVTGeY5kfGmxbjDhd5NigQ>? NF7NcG9,PiEQvF2= NXXIeHBNTE2VTx?= M1\kTolv\HWlZTDHNUBienKnc4S= M{nCXVI2QTV5OEGy
WM983a Mn71SpVv[3Srb36gZZN{[Xl? NIXlfVd,PiEQvF2= MkXNSG1UVw>? M2fsNYlv\HWlZTDHNUBienKnc4S= MVqyOVk2PzhzMh?=
WM164 Mni2SpVv[3Srb36gZZN{[Xl? M4LlZZ4{KM7:TR?= M{m5UGROW09? NGHUXHNifWevZX70d{BmgHC{ZYPzbY9vKG:oIF3IR{BkdGG|czDJJIFv\CCvZXzhco9u[SCjc4PvZ4lifGWmIHHueIlo\W6| M4\lNlI2QTV5OEGy
WM983a MUnGeY5kfGmxbjDhd5NigQ>? NYP2PYFvhjNizszN MWnEUXNQ M{DCSYF2\22nboTzJIV5eHKnc4Ppc44hd2ZiTVjDJINt[XO|IFmgZY5lKG2nbHHuc41iKGG|c3;jbYF1\WRiYX70bYdmdnN? Mkn1NlU6PTd6MUK=
IPC298 Mli3SpVv[3Srb36gZZN{[Xl? Mn\iglMh|ryP MXXEUXNQ MV\heYdu\W62czDlfJBz\XO|aX;uJI9nKE2KQzDjcIF{eyCLIHHu[EBu\Wyjbn;tZUBie3OxY3nheIVlKGGwdHnn[Y5{ M4nJSVI2QTV5OEGy
SKMEL30 M4j1bmZ2dmO2aX;uJIF{e2G7 NFzneY1,OyEQvF2= MVXEUXNQ MYXheYdu\W62czDlfJBz\XO|aX;uJI9nKE2KQzDjcIF{eyCLIHHu[EBu\Wyjbn;tZUBie3OxY3nheIVlKGGwdHnn[Y5{ NIDLVlQzPTl3N{ixNi=>
TCa83 NEjuRllHfW6ldHnvckBie3OjeR?= NFK5SXNqdmS3Y3XzJHBVTU5iZYjwdoV{e2mxbjDhcoQhdWWvYoLhcoUhfHKjboPsc4NifGmxbh?= NF7weG0zPjJ5OUOwNy=>
293T MVHGeY5kfGmxbjDhd5NigQ>? M1PuRp4zKM7:Zz;tcC=> NWHTdYhUcW6mdXPld{BRXEWQIHX4dJJme3Orb36gZY5lKG2nbXLyZY5mKHS{YX7zcI9k[XSrb36= NIrUXVczPjJ5OUOwNy=>
SACC-83 M2n6RmZ2dmO2aX;uJIF{e2G7 MkTRglIh|rypL33s NVPVZWk1cW6mdXPld{BRXEWQIHX4dJJme3Orb36gZY5lKG2nbXLyZY5mKHS{YX7zcI9k[XSrb36= NFSzXIczPjJ5OUOwNy=>
293T NV7jUpRFTnWwY4Tpc44h[XO|YYm= NVu2XY5ohjJizsznM41t M4PXbIlv\HWlZYOgVHRGViCjY3X0fYxifGmxbjDheEBMOTZ| NWX2OoRFOjZ{N{mzNFM>
U-87 MG M1j0S2Z2dmO2aX;uJIF{e2G7 MnzRglIh|rypL33s NGi5S3NqdmirYnn0d{B1cGVibXnndoF1cW:wIHHu[EBqdn[jc3nvci=> Mkj2NlYzPzl|MEO=
U-87 MG NEfybJdHfW6ldHnvckBie3OjeR?= M2\EVZ4yOCEQvF2= M1vDeolvcGmkaYTzJGFMXCCyaH;zdIhwenmuYYTpc44> M2[yNFI3Ojd7M{Cz
U-87 MG NEXPNpBIem:5dHigbY5pcWKrdH;yfUBie3OjeR?= M2C1W54yOCEQvF2= MoqzbY5pcWKrdIOgZ4VtdCCpcn;3eIg> MXyyOlI4QTNyMx?=

他の多くの細胞株試験データをご覧になる場合はこちらをクリックして下さい

体内試験 Daily treatment of Tubastatin A at 0.5mg/kg inhibits HDAC6 to promote Tregs suppressive activity in mouse models of inflammation and autoimmunity, including multiple forms of experimental colitis and fully major histocompatibility complex (MHC)-incompatible cardiac allograft rejection. [2]

お薦めの試験操作(参考用のみ)

キナーゼ試験:[1]
+ 展開

Enzyme Inhibition Assays:

Enzyme inhibition assays are performed by the Reaction Biology Corporation, Malvern, PA, using the Reaction Biology HDAC Spectrum platform. (www.reactionbiology.com) The HDAC1, 2, 4, 5, 6, 7, 8, 9, 10, and 11 assays use isolated recombinant human protein; HDAC3/NcoR2 complex is used for the HDAC3 assay. Substrate for HDAC1, 2, 3, 6, 10, and 11 assays is a fluorogenic peptide from p53 residues 379-382 (RHKKAc); substrate for HDAC8 is fluorogenic diacyl peptide based on residues 379-382 of p53 (RHKAcKAc). Acetyl-Lys (trifluoroacetyl)-AMC substrate is used for HDAC4, 5, 7, and 9 assays. Tubastatin A is dissolved in DMSO and tested in 10-dose IC50 mode with 3-fold serial dilution starting at 30 μM. Control Compound Trichostatin A (TSA) is tested in a 10-dose IC50 with 3-fold serial dilution starting at 5 μM. IC50 values are extracted by curve-fitting the dose/response slopes.
細胞試験: [1]
+ 展開
  • 細胞株: Primary cortical neuron of fetal Sprague-Dawley rats (embryonic day 17)
  • 濃度: 0-10 μM
  • 反応時間: 24 hours
  • 実験の流れ: Primary cortical neuron cultures are obtained from the cerebral cortex of fetal Sprague-Dawley rats (embryonic day 17) as described previously. All experiments are initiated 24 hours after plating. Under these conditions, the cells are not susceptible to glutamate-mediated excitotoxicity. For cytotoxicity studies, cells are rinsed with warm PBS and then placed in minimum essential medium (Invitrogen) containing 5.5 g/L glucose, 10% fetal calf serum, 2 mM L-glutamine, and 100 μM cystine. Oxidative stress is induced by the addition of the glutamate analogue homocysteate (HCA; 5 mM) to the media. HCA is diluted from 100-fold concentrated solutions that are adjusted to pH 7.5. In combination with HCA, neurons are treated with Tubastatin A at the indicated concentrations. Viability is assessed after 24 hours by MTT assay (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) method.
    (参考用のみ)
動物試験:[2]
+ 展開
  • 動物モデル: Na?ve CD45RBhi CD4+ CD25- cells (1 × 106) from WT or HDAC6-/- mice Are injected i.p. into B6/Rag1-/-mice.
  • 製剤: Tubastatin A is dissolved in dimethyl sulfoxide (DMSO).
  • 投薬量: 0.5 mg/kg
  • 投与方法: Tubastatin A is injected i.p. daily.
    (参考用のみ)

溶解度 (25°C)

体外 DMSO 74 mg/mL (198.99 mM)
Water Insoluble
Ethanol Insoluble
体内 左から(NMPから)右の順に溶剤を製品に加えます(文献ではなく、Selleckの実験によるデータ):
1% DMSO+30% polyethylene glycol+1% Tween 80
混合させたのち直ちに使用することを推奨します。
30 mg/mL

* 溶解度測定はSelleck技術部門によって行われており、その他文献に示されている溶解度と差異がある可能性がありますが、同一ロットの生産工程で起きる正常な現象ですからご安心ください。

化学情報

分子量 371.86
化学式

C20H21N3O2.HCl

CAS No. 1310693-92-5
保管
in solvent
別名 N/A

便利ツール

モル濃度計算器

モル濃度計算器

求めたい質量、体積または濃度を計算してください。

質量 (g) = 濃度 (mol/L) x 体積 (L) x 分子量 (g/mol)

モル濃度計算器方程式

  • 質量
    濃度
    体積
    分子量

*貯蔵液を準備するとき、常に、オンであるとわかる製品のバッチに特有の分子量を使って、を通してラベルとMSDS/COA(製品ページで利用可能な)。

希釈計算器

希釈計算器

貯蔵液を準備するために必要な希釈率を計算してください。Selleck希釈計算器は、以下の方程式に基づきます:

開始濃度 x 開始体積 = 最終濃度 x 最終体積

希釈の計算式

この方程式は、一般に略語を使われます:C1V1 = C2V2 ( 入力 出力 )

  • C1
    V1
    C2
    V2

常に貯蔵液を準備するとき、小びんラベルとMSDS/COA(オンラインで利用できる)で見つかる製品のバッチに特有の分子量を使ってください。

連続希釈計算器方程式

  • 連続希釈剤

  • 計算結果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量計算器

分子量计算器

そのモル質量と元素組成を計算するために、合成物の化学式を入力してください:

総分子量:g/mol

チップス: 化学式は大文字と小文字の区別ができます。C10H16N2O2 c10h16n2o2

モル濃度計算器

質量 濃度 体積 分子量

技術サポート

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HDACシグナル伝達経路

HDAC Inhibitors with Unique Features

相関HDAC製品

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大阪市内で「G20サミット」が開催されることに伴い、大阪府内で大規模な交通規制が行われる影響で、6月26日(水)から7月1日(月)までの間、下記地域へ出荷が行えなくなります。
対象地域
大阪府(全域)、兵庫県(芦屋市、尼崎市、伊丹市、西宮市)
上記地域より西の地域につきましては納期の遅延が予想されます。
また、国際便も遅延が予想されているため国内在庫がない製品の納期が一週間程度遅れる可能性がございます。
ご不便をおかけいたしますが、宜しくお願い申し上げます。

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細胞株 試験類型 濃度 培養時間 溶剤類型 活性叙述 PMID