Vorinostat (SAHA)

For research use only. Not for use in humans.

製品コードS1047 別名:MK0683, Suberoylanilide hydroxamic acid

Vorinostat (SAHA)化学構造

CAS No. 149647-78-9

Vorinostat (suberoylanilide hydroxamic acid, SAHA, MK0683) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay. Vorinostat abrogates productive HPV-18 DNA amplification.

サイズ 価格(税別)  
10mM (1mL in DMSO) JPY 33700
JPY 16000
JPY 26400
JPY 38500
最寄りの販売代理店を探す

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バルク問合せ

文献中Selleckの製品使用例(428)

製品安全説明書

HDAC阻害剤の選択性比較

生物活性

製品説明 Vorinostat (suberoylanilide hydroxamic acid, SAHA, MK0683) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay. Vorinostat abrogates productive HPV-18 DNA amplification.
ターゲット
HDAC [1]
(Cell-free assay)
~10 nM
体外試験

Vorinostat inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively. Vorinostat also results in a marked hyperacetylation of histone H4. [1] Vorinostat inhibits the growth of three prostate cancer cell lines LNCaP, PC-3 and TSU-Pr1 at micromolar concentrations (2.5-7.5 μM), and induces dose-dependent cell death in LNCaP cells. [2] Vorinostat treatment in MCF-7 cells inhibits cell proliferation at an IC50 of 0.75 μM resulting in the accumulation of cells in the G1 and G2-M phase of the cell cycle. Vorinostat also induces differentiation in the estrogen receptor-negative cell line SKBr-3 and the retinoblastoma-negative cell line MDA-468. [3] Vorinostat treatment at 1 μM for 8 hours or more is sufficient to irreversibly induce apoptosis of human multiple myeloma (MM) cells. The gene expression profiles of Vorinostat treated MM cells are not hallmarked by global transcriptional activation, but by coordinated transcriptional changes of specific functional groups of genes such as cytokine-induced proliferative/survival signaling cascades, oncogenes-tumor suppressor genes, regulators of apoptosis, DNA synthesis-repair and cell cycle, and proteasome-ubiquitin function. [4]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
H1299 M3iwS2tqdmG|ZTDBd5NigQ>? MVyyNEBucW5? M1f6dGROW09? M4ruZWlvcGmkaYTvdpkh[WO2aY\peJkh[WejaX7zeEBJTEGFIHXufplu\SC5aYToJGlEPTBib3[gNE4yQTRizszN M4C2WVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF2NUKxOFIzLz5zNEWyNVQzOjxxYU6=
HT1080 NYSxZ3FWT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUG3NkBp Mm[ySG1UVw>? NYXVelhXUUN3ME2yMlQh|ryP NHjjWGQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkK3NFE4PSd-MUKyO|AyPzV:L3G+
K562 NYexTm9XU2mwYYPlJGF{e2G7 NWLGdoxKPiCq MVLEUXNQ NFSyd5VKdmirYnn0bY9vKG:oIHj1cYFvKGirc4TvcoUh\GWjY3X0fYxie2ViKH3pfJR2emVib3[gTGRCSzFiYX7kJGhFSUN{KTD3bZRpKEmFNUCgc4YhOC5yMTFOwG0> MmnaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJ2MUmzPFAoRjF{NEG5N|gxRC:jPh?=
A20 NX\CZ4QzU2mwYYPlJGF{e2G7 NXnm[pF2OSCq MkjoSG1UVw>? NF;ndmJidnSrLVjERWMyKGGldHn2bZR6KHerdHigTWM2OCCxZjCwMlEyOiEQvF2= NH\tVZc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUm2NFQ5QSd-MUG5OlA1QDl:L3G+
Friend leukemic cell NFHLdWRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVu1NEDPxE1? MVy3NkBp NUTtdW92TE2VTx?= NU\KU3A5UUN3ME2wMlk6KM7:TR?= NGC2dWg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkGwPVkyOyd-MUKxNFk6OTN:L3G+
H1299 NF7aRpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnfnO|IhcA>? NYfZe5hiTE2VTx?= NI\BfVRKSzVyPUeuNlQh|ryP NVnBcVBIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUS1NlE1OjJpPkG0OVIyPDJ{PD;hQi=>
HeLa MWnLbY5ie2ViQYPzZZk> NGPTe2c{OCCvaX6= NXnLb4pGUW6qaXLpeI9zgSClb37j[Y51emG2aX;uJIFo[Wmwc4SgbIl{fG:wZTDk[YFk\XS7bHHz[UB4cXSqIFnDOVAhd2ZiMD6yPEDPxE1? MlraQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV4MEO5OFkoRjF3NkCzPVQ6RC:jPh?=
LOX-IMVI NY[w[4JST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVe0PEBp MnL5TWM2OD1zLkOg{txO MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTdzNUS3NEc,OTV5MUW0O|A9N2F-
NCI-H226 NUHPfY1CT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYCxdY91PDhiaB?= NEm4T|FKSzVyPUKuOkDPxE1? MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTdzNUS3NEc,OTV5MUW0O|A9N2F-
RXF-631L MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml7XOFghcA>? MlrETWM2OD1{IN88US=> MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTdzNUS3NEc,OTV5MUW0O|A9N2F-
SNB-78 NELEe25Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmO3OFghcA>? MWnJR|UxRTF4IN88US=> M{TDblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{G1OFcxLz5zNUexOVQ4ODxxYU6=
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ARP1 NIDpfYNHfW6ldHnvckBCe3OjeR?= Mn3hNkDPxE1? NVHLbYt7PiCq NHrC[GtKdmS3Y4Tpc44hd2ZiUEKxW2FHOSCpZX7lJIV5eHKnc4Ppc44> MnXEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR5M{S4NFYoRjF2N{O0PFA3RC:jPh?=
CEM M3i0PWtqdmG|ZTDBd5NigQ>? NV;yOYN4OSCq M3fCXWROW09? M4PlOWlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD6zN{DPxE1? M3z0eFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NEKwNFY1Lz5zNkSyNFA3PDxxYU6=
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NCI-H23 M1G0OGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV20PEBp NWPMPIppT0l3ME2wMlkzKM7:TR?= MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjd{M{KyO{c,OTZ5MkOyNlc9N2F-
GM15850 MlWxT4lv[XOnIFHzd4F6 MoL4Nk42KM7:TR?= MVe5OkBp NYGy[lE6TE2VTx?= NV7LUoZ5UW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJIhqe3SxbnWgTFMhdHm|aX7lJFE1KGGlZYT5cIF1cW:wIH;mJGZZViCpZX7l Ml60QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ7MkGzOlcoRjF4OUKxN|Y4RC:jPh?=
GM15850 NU\jSnMzU2mwYYPlJGF{e2G7 NHzTRpkzNjVizszN MYe5OkBp M37hOmROW09? NHuzTY9KdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgOUBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= NUPwc3ZnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[5NlE{PjdpPkG2PVIyOzZ5PD;hQi=>
GM15850 MX\LbY5ie2ViQYPzZZk> NILtdW4zNjVizszN M2SzSlk3KGh? MWrEUXNQ MonPTY5pcWKrdHnvckBw\iCKRFHDJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIHjpd5RwdmViSESgcJl{cW6nIEGyJIFk\XS7bHH0bY9vKG:oIF\YUkBo\W6n MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjl{MUO2O{c,OTZ7MkGzOlc9N2F-
GM15850 MYLLbY5ie2ViQYPzZZk> MXyyMlUh|ryP MUC5OkBp NX\tcVVWTE2VTx?= MVXJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iaHnzeI9v\SCKMzDsfZNqdmViOTDhZ4V1gWyjdHnvckBw\iCIWF6g[4Vv\Q>? NXy1[|JiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[5NlE{PjdpPkG2PVIyOzZ5PD;hQi=>
GM15850 NF74V3JMcW6jc3WgRZN{[Xl? MVyyMlUh|ryP MXm5OkBp MmX5SG1UVw>? NIn1V4JKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIOEBtgXOrbnWgPEBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= NFfNTXY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkmyNVM3Pyd-MU[5NlE{Pjd:L3G+
GM15850 M2rRemtqdmG|ZTDBd5NigQ>? MWCyMlUh|ryP M3LiOlk3KGh? M2nUVGROW09? MWrJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iaHnzeI9v\SCKNDDsfZNqdmViMU[gZYNmfHmuYYTpc44hd2ZiRmjOJIdmdmV? M{fzcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4OUKxN|Y4Lz5zNkmyNVM3PzxxYU6=
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U937 MV\GeY5kfGmxbjDBd5NigQ>? NVntTYF{OSEQvF2= NF3z[2gzPCCq MnvLSG1UVw>? M1rOSmVn\mWldDDvckBidHCqYTD0eYJ2dGmwIHHj[ZR6dGG2aX;u NV3GUWljRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFc4PTBpPkG3OFQ4PzVyPD;hQi=>
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RAW264.7 NHXYRVVHfW6ldHnvckBCe3OjeR?= MVqxNEDPxE1? MWeyOIg> NFHkeZJ4[XSnch?= MnvWTY5pcWKrdHnvckBw\iCOUGOtd5RqdXWuYYTl[EBPVyCycn;keYN1cW:wIIfpeIghUUN3MDDv[kAyNjh6IN88US=> Mn7YQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2N{e1NVgoRjF5NEe3OVE5RC:jPh?=
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CFBE41o- NF;JNmJMcW6jc3WgRZN{[Xl? MmPtOUDPxE1? NHfhOlQzPCCq MoTNSG1UVw>? M3Tk[2lvcGmkaYTpc44hd2ZiSFTBR|ch[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gd5Ri[mmuaYT5JI9nKE[mZXz0ZVUxQCCFRmTSJJBzd3SnaX6= MmnPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl7Nk[3PFkoRjF7OU[2O|g6RC:jPh?=
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Primary bronchial epithelial cell NILVb3dMcW6jc3WgRZN{[Xl? NGXx[Fg2KM7:TR?= MXqyOEBp NXL2TlU1TE2VTx?= NYCxVYNOUW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnu[JVkfGmxbjDv[kBufXSjboSgSoRmdHSjNUC4JGNHXFJicILveIVqdiCjcHnjZYwhe3W{ZnHj[UBtd2OjbHn6ZZRqd25? MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTl4Nke4PUc,OTl7Nk[3PFk9N2F-
Primary bronchial epithelial cell NYnO[GltU2mwYYPlJGF{e2G7 MWKxJO69VQ>? M2PscVk3KGh? NVLnbHdTTE2VTx?= NGCxNW5KdmirYnn0bY9vKG:oIFjERWM4KGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJJNpd3K2IHPpdoN2cXRiY4XydoVvfHN? NHviUFQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUm2Olc5QSd-MUm5OlY4QDl:L3G+
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CAL27 NU\QNIlPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXi3NkBp M2PHXWlEPTB;Mz63NkDPxE1? NULWUJNJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCxOFM4PzhpPkKwNVQ{Pzd6PD;hQi=>
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LNCAP MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MV[3NkBp Ml7FTWM2OD1yLkW4JO69VQ>? MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODF2M{e3PEc,OjBzNEO3O|g9N2F-
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SCC15 NWricmVtT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M17KdVczKGh? NFz5WIJKSzVyPUKuOFkh|ryP Mor6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjBzNEO3O|goRjJyMUSzO|c5RC:jPh?=
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SKHEP1 MoT5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXfhcnJzPzJiaB?= NV:3UHN{UUN3ME2zMlQ3KM7:TR?= NHHCT|g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEG0N|c4QCd-MkCxOFM4Pzh:L3G+
BJ MnXlS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NWS1SYk2OTByIN88US=> NWXONmFsPDhiaB?= NGC4cIFFVVOR M{nBfmdzd3e2aDDpcohq[mm2aX;uJIF1KDBwMEWgeI8hOTByIIXN MkDwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjBzNEO4OFAoRjJyMUSzPFQxRC:jPh?=
MUF M{jLWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MkT2NVAxKM7:TR?= NUf4botOPDhiaB?= Mmr2SG1UVw>? MnjnS5Jwf3SqIHnubIljcXSrb36gZZQhOC5yNTD0c{AyODBidV2= NHzObnM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEG0N|g1OCd-MkCxOFM5PDB:L3G+
Caco-2 NIHmPWpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NYTZemNIOTByIN88US=> NYHP[3I4PDiq M3zZT2ROW09? NFnQR3FKSzVyPUiuNUDPxE1? MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODF2M{i0NEc,OjBzNEO4OFA9N2F-
Caco-2 NW\lcHlzU2mwYYPlJGF{e2G7 MWO1JO69VQ>? M2D0Z|QhcA>? M3e4d2ROW09? NGW5b2VKdmS3Y4Tpc44hd2ZiSFTBR{1u\WSrYYTl[EBpcXO2b37lJIFk\XS7bHH0bY9vKEmFNUCgc4YhOC5yM{eg{txO M3:0ZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyMUSzPFQxLz5{MEG0N|g1ODxxYU6=
Caco-2 MVjLbY5ie2ViQYPzZZk> M{LnWlAvOzF4IH7NJJRwKDNzLk[g{txO MlfkOEBp MmP3SG1UVw>? MlHkSZghfmm4bzDpcohq[mm2aX;uJI9nKGi3bXHuJGhFSUNzIIfpeIghUUN3MDDv[kAxNjFzOTFOwG0> MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODF2M{i0NEc,OjBzNEO4OFA9N2F-
Caco-2 MVLLbY5ie2ViQYPzZZk> MmTGNE4{OTZibl2geI8hOzFwNjFOwG0> MnzpOEBp NV7PdI1VTE2VTx?= MXPFfEB3cX[xIHnubIljcXSrb36gc4YhcHWvYX6gTGRCSzNid3n0bEBKSzVyIH;mJFAvOTR5IN88US=> NGj3UWo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEG0N|g1OCd-MkCxOFM5PDB:L3G+
Caco-2 M1nSVWtqdmG|ZTDBd5NigQ>? M2PseVYvOzJibl2geI8hPjN{IN88US=> NVr0XpdbPCCq NVnqXZE6TE2VTx?= MojLSZghfmm4bzDpcohq[mm2aX;uJI9nKGi3bXHuJGhFSUN3IIfpeIghUUN3MDDv[kAyOi54IN88US=> MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODF2M{i0NEc,OjBzNEO4OFA9N2F-
Caco-2 NED0cpRMcW6jc3WgRZN{[Xl? NX3OWIpOPi5|MjDuUUB1dyB4M{Kg{txO Mn;uOEBp MVHEUXNQ M{XoPGV5KH[rdn:gbY5pcWKrdHnvckBw\iCqdX3hckBJTEGFNzD3bZRpKEmFNUCgc4YhPDFizszN NYHSWGZURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCxOFM5PDBpPkKwNVQ{QDRyPD;hQi=>
Caco-2 NY[xdmxKU2mwYYPlJGF{e2G7 M3zYflAvOzF4IH7NJJRwKDNzLk[g{txO M3naR|QhcA>? NYDuXoV5TE2VTx?= NWPqcXBMTXhidnn2c{BqdmirYnn0bY9vKG:oIHj1cYFvKEiGQVO2 NEnrVoE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEG0N|g1OCd-MkCxOFM5PDB:L3G+
HepG2 MlzuT4lv[XOnIFHzd4F6 NI\lT3A2KM7:TR?= MkHjOog> NXrJZlFSTE2VTx?= MX7JcoR2[3Srb36gc4YhUESDQz3t[YRq[XSnZDDobZN1d26nIHHj[ZR6dGG2aX;u MknLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjBzNEO4OFAoRjJyMUSzPFQxRC:jPh?=
HepG2 M3TSfWtqdmG|ZTDBd5NigQ>? MoDZOUDPxE1? Mn72Oog> MWPEUXNQ MonFTY5lfWO2aX;uJI9nKEiGQVOtcYVlcWG2ZXSgbIl{fG:wZTDofZBmemGlZYT5cIF1cW:w MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODF2M{i0NEc,OjBzNEO4OFA9N2F-
HepG2 NHvjd2dMcW6jc3WgRZN{[Xl? Mkn0OUDPxE1? MmfSOog> NWfPR4lUTE2VTx?= MnTTTY5lfWO2aX;uJI9nKEiGQVOtcYVlcWG2ZXSgZYxxcGFvdIXieYxqdiCjY3X0fYxifGmxbh?= MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODF2M{i0NEc,OjBzNEO4OFA9N2F-
HepG2 MWrLbY5ie2ViQYPzZZk> NE\EXGQ2KM7:TR?= MYm2bC=> MVLEUXNQ MknSTY5lfWO2aX;uJI9nKEiGQVOtcYVlcWG2ZXSgTFMwUDRiaHnzeI9v\SCjY3X0fYxifGmxbh?= MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODF2M{i0NEc,OjBzNEO4OFA9N2F-
COLO205 M2LvemtqdmG|ZTDBd5NigQ>? M2DCU|ExKM7:TR?= NUDFZ3FWOjRiaB?= NXnJ[25NTE2VTx?= MmfOTY5pcWKrdHnvckBw\iCKRFHDNUBie3Onc4Pl[EBieyCrbnT1Z5Rqd25ib3[gbIl{fG:wZTDIN{Bi[2W2eXzheIlwdiC5aYToJGlEPTBib3[gNk4zKM7:TR?= NEDDb3g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MES1NVM4QCd-MkC0OVE{Pzh:L3G+
SCC4 MYjLbY5ie2ViQYPzZZk> NIqyWnQyKM7:TR?= M3nQPFI1cA>? MVLJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5idIXieYxqdiCjY3X0fYxifGmxbh?= NX;N[mI3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0OVIzOjVpPkKwOFUzOjJ3PD;hQi=>
SCC4 NIPEO29McW6jc3WgRZN{[Xl? NES0bnkyKM7:TR?= NXrjR4htOjSq MWDJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iaHnzeI9v\SCjY3X0fYxifGmxbh?= NE\uPYs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MES1NlIzPSd-MkC0OVIzOjV:L3G+
SCC4 M3TBUGZ2dmO2aX;uJGF{e2G7 NFnzcWgyKM7:TR?= NXjiTHZNPSCvaX6= MojBRYdwdmm|dDDhZ5Rqfmm2eTDheEBXTFJiYYPz[ZN{\WRiYYOgbY5lfWO2aX;uJI9nKEO\UEK0JIdmdmViZYjwdoV{e2mxbh?= MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODR3MkKyOUc,OjB2NUKyNlU9N2F-
NB4 NUDSeVZYTnWwY4Tpc44hSXO|YYm= MVm1JO69VQ>? NUL5O4FHOjRiaB?= M{W1fGROW09? MX7D[YxtKGO7Y3zlJIFzemW|dDDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCjY3P1cZVt[XSrb36gZZQheHKnLVexJJBp[XOn MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODR7MUS0NEc,OjB2OUG0OFA9N2F-
NB4 NETwb3NMcW6jc3WgRZN{[Xl? M4nLe|Uh|ryP NX;2U3I{OjRiaB?= NEXuNFNFVVOR MnfaTY5pcWKrdHnvckBw\iCKRFHDJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIHHj[ZR6dGG2ZTD0eYJ2dGmwIHzleoVt NWq2SGdFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0PVE1PDBpPkKwOFkyPDRyPD;hQi=>
NB4 M2PqTWZ2dmO2aX;uJGF{e2G7 NHPvblE2KM7:TR?= NILSb3AzPCCq MWXEUXNQ M3XsR2lv\HWldHnvckBw\iCyMkHXRWYyN0OLUEGg[ZhxemW|c3nvci=> MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODR7MUS0NEc,OjB2OUG0OFA9N2F-
NB4 NEPU[4FMcW6jc3WgRZN{[Xl? NEXSSFY2KM7:TR?= NEjmZm8zPCCq MV3EUXNQ MWjJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iaHnzeI9v\SCKMzDhZ4V1gWyjdHnvci=> NX;0c5dkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0PVE1PDBpPkKwOFkyPDRyPD;hQi=>
NUGC3 Mn;4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVrHTVUxRTJwOUSg{txO NFLGOHA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEi1NFk4OSd-MkC4OVA6PzF:L3G+
A549 NUPGcpJUTnWwY4Tpc44hSXO|YYm= M1;afVUh|ryP NIXBOHg{KGh? M363NWROW09? MYXJcoR2[3Srb36gc4Yh[XW2b4DoZYd6KGmwIHj1cYFvKEF3NEmgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5kemWjc3WgbY4hVEN|SVm= MmOwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUWyNFgoRjJyOEW1NlA5RC:jPh?=
HUT78 NEDtXIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUO3NkBp MV;EUXNQ NF[0WIxIUTVyPUCuN{DPxE1? MlzhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6OESyNFgoRjJyOEi0NlA5RC:jPh?=
U937 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{jxcFczKGh? M4HHSWROW09? Ml:xS2k2OD1yLkO5JO69VQ>? M1v6cVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOEi0NlA5Lz5{MEi4OFIxQDxxYU6=
A431 MY\DfZRwfG:6aXOgRZN{[Xl? MlvqO|IhcA>? NXzTS5VYS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTR|MTDj[YxteyCxdnXy[ZhxemW|c3nu[{BGT0[UIIfpeIghUUN3MDDv[kA1NjJizszN MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB6ME[yPUc,OjFyOEC2Nlk9N2F-
A549 NUTxe2JrS3m2b4TvfIlkKEG|c3H5 MljKO|IhcA>? MkDvR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gRVU1QSClZXzsd{BwfmW{ZYjwdoV{e2mwZzDISGFEKHerdHigTWM2OCCxZjCxMlgh|ryP M{X2ZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEiwOlI6Lz5{MUC4NFYzQTxxYU6=
CAL27 NWiyfJp6S3m2b4TvfIlkKEG|c3H5 MXG3NkBp NIfpZ|NEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBESUx{NzDj[YxteyCxdnXy[ZhxemW|c3nu[{BGT0[UIIfpeIghUUN3MDDv[kA{NjJizszN M1mxcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEiwOlI6Lz5{MUC4NFYzQTxxYU6=
HeLa MnzwR5l1d3SxeHnjJGF{e2G7 NIXscIQ4OiCq NVHsPHBIS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hUGWOYTDj[YxteyCxdnXy[ZhxemW|c3nu[{BJTEGFIIfpeIghUUN3MDDv[kAyNjVizszN NHjRS5E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC4NFYzQSd-MkGwPFA3Ojl:L3G+
Sf21 M3jLcWtqdmG|ZTDBd5NigQ>? NGHoUnQ{KGh? M1HqfmlvcGmkaYTpc44hd2ZiRnzh[{B1[WepZXSgbJVu[W5icnXjc41jcW6jboSgTGRCSzhiZYjwdoV{e2WmIIfpeIghUUN3MDDv[kAyNjJizszN MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB6ME[yPUc,OjFyOEC2Nlk9N2F-
SKBR3 MnzCR5l1d3SxeHnjJGF{e2G7 Ml\UO|IhcA>? M4TWR2N6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNMSlJ|IHPlcIx{KG:4ZYLlfJBz\XO|aX7nJGhGWjJid3n0bEBKSzVyIH;mJFIvPiEQvF2= Mnf6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyOEC2NlkoRjJzMEiwOlI6RC:jPh?=
SKOV3 M3vwT2N6fG:2b4jpZ{BCe3OjeR?= NF7FXJQ4OiCq M{nYdGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJHNMV1Z|IHPlcIx{KG:4ZYLlfJBz\XO|aX7nJGhGWjJid3n0bEBKSzVyIH;mJFIvOiEQvF2= MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB6ME[yPUc,OjFyOEC2Nlk9N2F-
COR-L23 NUS3NmZCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFvPcXUyOCEQvF2= MV23NkBp NF\aT|hFVVOR MWDHTVUxRTFwMTFOwG0> M2\iNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEiwOlQ4Lz5{MUC4NFY1PzxxYU6=
DU145 NFfzfIdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmXvNVAh|ryP NUTZcnlHPzJiaB?= MXnEUXNQ NUHlToFbT0l3ME2xMlA2KM7:TR?= M2H3bVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEiwOlQ4Lz5{MUC4NFY1PzxxYU6=
LoVo M3f2R2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NUfYcG53OTBizszN M{LXflczKGh? MnPRSG1UVw>? NX3WXoFKT0l3ME2xMlch|ryP MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB6ME[0O{c,OjFyOEC2OFc9N2F-
MCR5-SV2 NEPGXXhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3P1TlExKM7:TR?= NGe2bW04OiCq MULEUXNQ MUnHTVUxRTJwMTFOwG0> MmLzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyOEC2OFcoRjJzMEiwOlQ4RC:jPh?=
HCT116 M3T3R2tqdmG|ZTDBd5NigQ>? M17pPFMxKM7:TR?= M3zZW|MxKGh? NX7CTJFETE2VTx?= NXXBNmNYUW6qaXLpeIlwdiCxZjDISGFEPiCjc4Pld5Nm\CCjczDpcoR2[3Srb36gc4Yh[WyyaHGteJVjfWyrbjDhZ4V1gWyjdHnvci=> NHr4PG09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC4NFY1Pyd-MkGwPFA3PDd:L3G+
HCT116 M2fhSGtqdmG|ZTDBd5NigQ>? M2rFbVMxKM7:TR?= NHjFZpQ{OCCq NYnV[XJvTE2VTx?= MWHJcohq[mm2aX;uJI9nKEiGQVOxJIF{e2W|c3XkJIF{KGmwZIXjeIlwdiCxZjDobZN1d26nIFizT|kh[WOndInsZZRqd25? M4HGbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEiwOlQ4Lz5{MUC4NFY1PzxxYU6=
U937 MYPLbY5ie2ViQYPzZZk> M{W4cFUh|ryP NU\IUWh6OjRiaB?= MVnEUXNQ MnHuTY5pcWKrdHnvckBw\iCqaYP0c45mKGGlZYT5cJRz[W6|ZnXyZZNmKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIH;mJIFk\XS7bHH0bY9vKG:oIHjpd5RwdmViSEOgZZQhUzl? M1nKVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMkmyOFkzLz5{MUK5NlQ6OjxxYU6=
U937 NUDWfXYzU2mwYYPlJGF{e2G7 M1fJSVUh|ryP NILzdXIzPCCq MnztSG1UVw>? MofyTY5pcWKrdHnvckBw\iCqaYP0c45mKGGlZYT5cJRz[W6|ZnXyZZNmKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIH;mJIFk\XS7bHH0bY9vKG:oIHjpd5RwdmViSEOgZZQhUzF6 MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTJ7MkS5Nkc,OjF{OUK0PVI9N2F-
U937 MXLLbY5ie2ViQYPzZZk> M3rlNlUh|ryP NUC2[GVSOjRiaB?= M33QXGROW09? MliwTY5pcWKrdHnvckBw\iCqaYP0c45mKGGlZYT5cJRz[W6|ZnXyZZNmKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIH;mJJBidi2jY3X0fYxifGWmIHjpd5RwdmViSESgcIV3\Wx? M2PMelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMkmyOFkzLz5{MUK5NlQ6OjxxYU6=
U937 Mn\tT4lv[XOnIFHzd4F6 MoDsOUDPxE1? NV;Bd5V2OTVibXnu NXPETmRHTE2VTx?= NYHYbGVGUW6qaXLpeIlwdiCxZjDobZN1d26nIHHj[ZR6dHS{YX7z[oVz[XOnIHHzd4V{e2WmIHHzJIlv[3KnYYPlJI9nKGirc4TvcoUhUDNiYXPleJlt[XSrb36gcIV3\Wx? NGTaSpI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5NlQ6Oid-MkGyPVI1QTJ:L3G+
A2780 NXT5[WNOT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYq5OkBp Mn\xSG1UVw>? NH25RpdKSzVyPUGuOlIh|ryP NYLS[ZVXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG2N|Q1OzBpPkKxOlM1PDNyPD;hQi=>
COLO205 MUDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NGO5Zow6PiCq NVewZno6TE2VTx?= MXLJR|UxRTJwMUKg{txO NIP1SHA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MU[zOFQ{OCd-MkG2N|Q1OzB:L3G+
Hep3B MoTrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mm\6OFghcA>? MljxSG1UVw>? M1zpUmdKPTB;MT6yNUDPxE1? M{S5N|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzN{GyNVQ3Lz5{MUexNlE1PjxxYU6=
GM11272 Mn\QSpVv[3Srb36gRZN{[Xl? NY\XVnhnOTByIH7N NYixdWNnPzJiaB?= M2S3bGROW09? NVnJN3BMWmWjY4TpeoF1cW:wIH;mJG1mS3B{IH31eIFvfCCneIDy[ZN{cW:wIHH0JFExKHSxIEGwNEBvVQ>? MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh2MEexOkc,OjF6NEC3NVY9N2F-
CFBE41o NYLFTXJyU2mwYYPlJGF{e2G7 NV\aRmw{PSEQvF2= NV21VWc4TE2VTx?= M3y1RWRwf25icnXneYxifGmxbjDv[kBJTEGFNzDheEAxNjJidH:gOUB2VQ>? MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl6NEm1PEc,OjF7OES5OVg9N2F-
CFBE41o Mm[2SpVv[3Srb36gRZN{[Xl? NF;EcWYyKM7:TR?= M1zITVI1KGh? Mki5SG1UVw>? NGfDOVlT\XO2b4LheIlwdiCxZjDDSnRTKGSnbIThSlUxQCCvdYThcpQhfHKjZn\pZ4tqdmdidH:gZ4VtdCC|dYLmZYNmKGG|IHfsfYNw\m:{bYO= MkfkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7OES5OVgoRjJzOUi0PVU5RC:jPh?=
DU145 NXnKOVhSU2mwYYPlJGF{e2G7 MmPxNk42KM7:TR?= Ml7lNlQhcA>? NYqxeZdoTE2VTx?= M3HCeWlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyC3cILl[5Vt[XSrb36gc4YheDJzd3HmNUBxem:2ZXnuJIV5eHKnc4Ppc44> NFnTXlM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkK2NFE3Pid-MkKyOlAyPjZ:L3G+
DU145 NXLVeVYxU2mwYYPlJGF{e2G7 MWq1JO69VQ>? NGXLNmIzPCCq NYf2OGJnTE2VTx?= NFvjZVBKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaHnzeI9v\SCKNDDhZ4V1gWyjdHnvci=> MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjJ4MEG2Okc,OjJ{NkCxOlY9N2F-
DU145 NXHlWlZwU2mwYYPlJGF{e2G7 NYjCTm1zPSEQvF2= NGHTOFkzPCCq M1;ocGROW09? MVzJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcGm|dH;u[UBJOyCqeYDldoFk\XS7bHH0bY9v NImzcY09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkK2NFE3Pid-MkKyOlAyPjZ:L3G+
786-0 MlP1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MmjxOk4zKM7:TR?= MXW3NkBp NULPXo03TE2VTx?= NYDGb4wzT0l3ME2zMlIh|ryP MnPLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
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A549/ATCC M{fQWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoD3Ok4zKM7:TR?= NXX0c|J[PzJiaB?= NFjwV4dFVVOR MU\HTVUxRTFwNjFOwG0> NVTURpFrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
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BT549 NILWeJdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NW[0e4doPi5{IN88US=> NFnYUY84OiCq MojFSG1UVw>? NG[3Om9IUTVyPUGuN{DPxE1? NF7RPFk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
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HOP92 NGTwSnlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NVnXWng1Pi5{IN88US=> MVe3NkBp MlH2SG1UVw>? Mn;HS2k2OD12IN88US=> M2e3WVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
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MALME-3M MkPNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{XibVYvOiEQvF2= M3G2eVczKGh? NYTvNHYyTE2VTx?= NVXiR2ZHT0l3ME2wMlMzKM7:TR?= M1jNflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
MCF10A MoK5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH7XV|c3NjJizszN NWf5VHFpPDhiaB?= MnnVSG1UVw>? MYTHTVUxRTlwNjFOwG0> MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
MDA-MB-435 NYG5[Wo5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFzRV3k3NjJizszN M4fDN|czKGh? MoLTSG1UVw>? M1vm[WdKPTB;MD61JO69VQ>? MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
MDA-MB-468 NXna[|RST3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NVWwV5lMPi5{IN88US=> NGTGVlg4OiCq MlflSG1UVw>? MVLHTVUxRTBwNkOg{txO M4HQVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
MOLT4 MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYnEeWdRPi5{IN88US=> NFLR[2g4OiCq M2PrTWROW09? NHXSXXVIUTVyPUCuOEDPxE1? M4DvWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
NCI-ADR-RES NUm3UGFQT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MUC2MlIh|ryP M2nv[FczKGh? Mkf1SG1UVw>? MYnHTVUxRTBwMU[g{txO NFzwZmw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
NCI-H23 M1fNWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1v0cFYvOiEQvF2= NITEXWY4OiCq M{\JbWROW09? NUC3OWh4T0l3ME2xJO69VQ>? NED3dlQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
NCI-H322M MnH0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NX\SZm9qPi5{IN88US=> NEiwfXI4OiCq MlPESG1UVw>? MVjHTVUxRTBwN{mg{txO NHrReZY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
NCI-H460 NUizeIV3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MWS2MlIh|ryP MVu3NkBp NITPSnVFVVOR MYrHTVUxRTBwN{mg{txO NF3OUJI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
NCI-H522 NFvxTIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH\FdVk3NjJizszN MYW3NkBp M3\STmROW09? MnrRS2k2OD1yLkWg{txO MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
OVCAR3 MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVjnPI5jPi5{IN88US=> NYXDVnF5PzJiaB?= M2D2b2ROW09? MomxS2k2OD1zLkOg{txO MnzCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
OVCAR4 Mlv4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4HURVYvOiEQvF2= NXf0b3VoPzJiaB?= MoTXSG1UVw>? NVPUTJhOT0l3ME20JO69VQ>? MnTJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
OVCAR5 NEHS[WxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NILYfFU3NjJizszN MVq3NkBp NXqzc4liTE2VTx?= MmS0S2k2OD1yLke5JO69VQ>? NF3vRYU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
OVCAR8 NFTrV3BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NE\0Z4Q3NjJizszN M2LDbFczKGh? MmXWSG1UVw>? NGmyZplIUTVyPUCuOUDPxE1? NUjrWHJ5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
RXF393 MnrjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M3TRPFYvOiEQvF2= M4jYOFczKGh? MYXEUXNQ NHvRXXJIUTVyPUGuN{DPxE1? NF3xcHg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
SF268 NIHaT3hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXTVdmhRPi5{IN88US=> MmL3O|IhcA>? M4fQU2ROW09? MlzmS2k2OD1zLk[g{txO MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
SF295 NWn4Sog1T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MVm2MlIh|ryP NYm1U2Q{PzJiaB?= M4ruOWROW09? NYfYV4I4T0l3ME2xMlYh|ryP MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
SF539 NFTablBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mmr0Ok4zKM7:TR?= Mnj1O|IhcA>? M37WUGROW09? NE[1W|BIUTVyPUKg{txO M3fSTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
SK-MEL-2 M{P0b2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M{PVUlYvOiEQvF2= NEGzS5E4OiCq NHvx[YZFVVOR NWfYdYhuT0l3ME2xMlMh|ryP MoXSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
SK-MEL-28 NHfvRmZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1[0XVYvOiEQvF2= NX:yW48{PzJiaB?= NIC0R4JFVVOR M1jyUWdKPTB;MTFOwG0> NIKwZW09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
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SKOV3 Mn;PS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUW2MlIh|ryP MX23NkBp MV;EUXNQ MWDHTVUxRTFizszN NInDRng9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
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TK10 MnvyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXfpdVZ[Pi5{IN88US=> NG\Hc|U4OiCq MUTEUXNQ MnKwS2k2OD1yLk[zJO69VQ>? MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
UACC257 MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NULiVWR2Pi5{IN88US=> MU[3NkBp M3PnN2ROW09? NU\6PGlXT0l3ME2wMlUh|ryP MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
UACC62 NIe3NYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlzvOk4zKM7:TR?= M{LuRVczKGh? NYHrelBvTE2VTx?= NF3ObYtIUTVyPUCuOEDPxE1? MnvIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
UO31 M{XyeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWfNZottPi5{IN88US=> NYfRT2dYPzJiaB?= NY\wfoVFTE2VTx?= Mn;HS2k2OD1yLkWg{txO NXWzcZRjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
Hep3B NXzHZnB3T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NFnqdlc1QCCq NX;kWGpmTE2VTx?= M{fFRmdKPTB;MD62PUDPxE1? NXnjcJRlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|k5PjNpPkKyOFM6QDZ|PD;hQi=>
BE(2)-C NGDxSHlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M4XMRlczKGh? NXnaNno2TE2VTx?= M17wbmlEPzB;MjFOwG0> MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl|MkOxOkc,OjJ7M{KzNVY9N2F-
Bel7402 Mn3WS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mmf5O|IhcA>? M3\PS2ROW09? M1:1UGdKQTB;MUeg{txO NHPHZnE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C2NVM4Pid-MkOwOlE{PzZ:L3G+
Bel7404 NFrw[YdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3nGOFczKGh? NWDUUZJrTE2VTx?= MlTFS2k6OD1zODFOwG0> NVu4c2JtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOwOlE{PzZpPkKzNFYyOzd4PD;hQi=>
BGC823 MlvGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH[wN3k4OiCq MYjEUXNQ Mnm1S2k6OD15LkWg{txO MnnUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNyNkGzO|YoRjJ|ME[xN|c3RC:jPh?=
MGC803 M3rXO2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVK3NkBp NES3TnFFVVOR NFvFfnlIUTlyPUGwMlgh|ryP MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB4MUO3Okc,OjNyNkGzO|Y9N2F-
SGC7901 NVzOWWZFT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MkXUO|IhcA>? M2nTfGROW09? NWHvZW57T0l7ME25MlQh|ryP NFK4TXc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C2NVM4Pid-MkOwOlE{PzZ:L3G+
SKHEP1 NH3Kb2hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH:5Z3I4OiCq NHTlZm5FVVOR NITnW45IUTlyPUG3JO69VQ>? M13DPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|ME[xN|c3Lz5{M{C2NVM4PjxxYU6=
SMMC7721 MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NUK3TIFwPzJiaB?= MVPEUXNQ NX\vZlZDT0l7ME2yNEDPxE1? M{D5WFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|ME[xN|c3Lz5{M{C2NVM4PjxxYU6=
NUGC3 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVz0PWI3OTBizszN M1rub2dKRTJwOUSg{txO NEDYdIw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G2N|M{Oid-MkOxOlM{OzJ:L3G+
A2780 CisR MnXOT4lv[XOnIFHzd4F6 MkTjNVghcA>? NGPwboxKdmirYnn0bY9vKG:oIFjERWMhf2m2aDDJR|UxKG:oIECuOFQh|ryP M{mzWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkWyOlA{Lz5{M{K1NlYxOzxxYU6=
CAL27 sens MmDqT4lv[XOnIFHzd4F6 MXKxPEBp M2LvSmlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD6zOkDPxE1? MnW0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{NUK2NFMoRjJ|MkWyOlA{RC:jPh?=
CAL27 CisR MVTLbY5ie2ViQYPzZZk> MmCzNVghcA>? MYTJcohq[mm2aX;uJI9nKEiGQVOge4l1cCCLQ{WwJI9nKDBwNkGg{txO NGjLTIo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{K1NlYxOyd-MkOyOVI3ODN:L3G+
KYSE-510 CisR M4\J[WtqdmG|ZTDBd5NigQ>? MYSxPEBp NXzsd|N6UW6qaXLpeIlwdiCxZjDISGFEKHerdHigTWM2OCCxZjCwMlU6KM7:TR?= MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzJ3Mk[wN{c,OjN{NUK2NFM9N2F-
KYSE-510 sens MknYT4lv[XOnIFHzd4F6 NH7NdIwyQCCq MoTRTY5pcWKrdHnvckBw\iCKRFHDJJdqfGhiSVO1NEBw\iByLkeg{txO M1zNPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkWyOlA{Lz5{M{K1NlYxOzxxYU6=
MDA-MB-231 sens NXLhR4RwU2mwYYPlJGF{e2G7 MYGxPEBp MYDJcohq[mm2aX;uJI9nKEiGQVOge4l1cCCLQ{WwJI9nKDBwNkGg{txO NH7ib4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{K1NlYxOyd-MkOyOVI3ODN:L3G+
MDA-MB-231 CisR M2fWeGtqdmG|ZTDBd5NigQ>? NES0OWoyQCCq NYW2ZohuUW6qaXLpeIlwdiCxZjDISGFEKHerdHigTWM2OCCxZjCwMlYyKM7:TR?= NULCOXZRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyOVI3ODNpPkKzNlUzPjB|PD;hQi=>
ES2 MlvKS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NH63XHU1QCCq NVnpOnVkTE2VTx?= M{TVc2lEPTB;MUKuO{DPxE1? MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzR7M{S0PUc,OjN2OUO0OFk9N2F-
MDA-MB-231 MlLhT4lv[XOnIFHzd4F6 M2jJOFExKM7:TR?= MX:zNEBucW5? MnG2SG1UVw>? M1;RVmlvcGmkaYTpc44hd2ZiSFTBR|Ji NHTZR3Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{S5N|Q1QSd-MkO0PVM1PDl:L3G+
MDA-MB-231 M4TQXmtqdmG|ZTDBd5NigQ>? M4LmSlEh|ryP NYLOSIVXOjRiaB?= M13sUGROW09? NYXUR3FYUW6qaXLpeIlwdiCxZjDISGFEPiCjc4Pld5Nm\CCjczDhZ4V1gWyjdHnvckBt\X[nbIOgc4YhfHWkdXzpci=> MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzR7M{S0PUc,OjN2OUO0OFk9N2F-
HS68 M3m2RmN6fG:2b4jpZ{BCe3OjeR?= NHHMVoYyOCEQvF2= M3XuXFczKGh? NV;OZpprTE2VTx?= M3G5bGlEPTB;ND62JO69VQ>? NXz2[oZRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO1O|A2PDJpPkKzOVcxPTR{PD;hQi=>
MEF MXfDfZRwfG:6aXOgRZN{[Xl? MkHWNVAh|ryP M4rHflczKGh? MVLEUXNQ NXnwXWZ5UUN3ME20MlQh|ryP M1rMSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NUewOVQzLz5{M{W3NFU1OjxxYU6=
BGC823 MlTMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2OyOmROW09? NWDxOG1rT0l3ME2zMlA6KM7:TR?= NWfJV2R3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2NFE4ODZpPkKzOlAyPzB4PD;hQi=>
High5 NEPVVo5McW6jc3WgRZN{[Xl? Mk\xNlQhcA>? NVPSTIpQUW6qaXLpeIlwdiCxZjDoeY1idiC{ZXPvcYJqdmGwdDDISGFEPiC5aYToJGlEPTBib3[gNE4xQSEQvF2= M4e3eVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkCyOVI{Lz5{M{[wNlUzOzxxYU6=
High5 MXrLbY5ie2ViQYPzZZk> M1f4flI1KGh? MkDDTY5pcWKrdHnvckBw\iCqdX3hckBz\WOxbXLpcoFvfCCKRFHDNUB4cXSqIFnDOVAhd2ZiMD6xNkDPxE1? MlfOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4MEK1NlMoRjJ|NkCyOVI{RC:jPh?=
High5 NFTxd4FMcW6jc3WgRZN{[Xl? MmizNlQhcA>? NHr0[FZKdmirYnn0bY9vKG:oIHj1cYFvKHKnY3;tZolv[W62IFjERWM{KHerdHigTWM2OCCxZjCwMlE4KM7:TR?= NWrGUodJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2NFI2OjNpPkKzOlAzPTJ|PD;hQi=>
A549 M{TWXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NHi5bHdFVVOR MXrJR|UxRTFwMEe5JO69VQ>? MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ2NEKxNEc,OjN4NESyNVA9N2F-
HCT116 M2XjVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MmO0SG1UVw>? NHrscG1KSzVyPUCuO|U4KM7:TR?= MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ2NEKxNEc,OjN4NESyNVA9N2F-
K562 Mn34S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVHEUXNQ NGfD[lZKSzVyPUCuOlQ2KM7:TR?= MnvRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4NESyNVAoRjJ|NkS0NlExRC:jPh?=
GBC-SD MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MoW3OUDPxE1? MVu3NkBp M4TncmROW09? NVvYPGI3UUN3ME2xOE45KM7:TR?= NVO4b4NyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO3NFczPjBpPkKzO|A4OjZyPD;hQi=>
HGC27 MlzTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1zpfVUh|ryP NHHORnM4OiCq MWjEUXNQ NX;xU2FjUUN3ME21MlQh|ryP NF\qWHY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{ewO|I3OCd-MkO3NFczPjB:L3G+
HL60 NETqT3hMcW6jc3WgRZN{[Xl? NHrnOIc2KM7:TR?= MX2yOEBp NGHmUYtFVVOR NUnmNlBGUW6qaXLpeIlwdiCxZjDISGFE MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzdyN{K2NEc,OjN5MEeyOlA9N2F-
Vero MkDQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIXYbnE4OiCq NF7neXVFVVOR MYLJR|UxRTBwOTFOwG0> NYLaOnpVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO3PFY1PTJpPkKzO|g3PDV{PD;hQi=>
NCI60 M4HrWmN6fG:2b4jpZ{BCe3OjeR?= M1myPVQ5KGh? NVzqUlF7TE2VTx?= MYrHTV0xNjV|IN88US=> M4S0dlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEG1N|I4Lz5{NECxOVMzPzxxYU6=
SW620 M4W2XWN6fG:2b4jpZ{BCe3OjeR?= Mo\jOFghcA>? MXrEUXNQ Mm\WS2k:OC53NDFOwG0> MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDBzNUOyO{c,OjRyMUWzNlc9N2F-
U251 Mn7sR5l1d3SxeHnjJGF{e2G7 NHvwVYU1QCCq NIjMVpJFVVOR M{fwemdKRTFwNUOg{txO MlWyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyMUWzNlcoRjJ2MEG1N|I4RC:jPh?=
KM12 NGXPeWREgXSxdH;4bYMhSXO|YYm= NFjCOFU1QCCq M4H4emROW09? MWfHTV0yNjh6IN88US=> NWOyRZJoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwNVU{OjdpPkK0NFE2OzJ5PD;hQi=>
Hs578T NWXMR5p2S3m2b4TvfIlkKEG|c3H5 NWS3[ZdUPDhiaB?= MlTvSG1UVw>? M4LufGdKRTRwOEOg{txO NIr5T4U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NECxOVMzPyd-MkSwNVU{Ojd:L3G+
MDA-MB-231 NHrZcXBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MV20PEBp M3j5T2lEPTB;MD6xOkDPxE1? MoXTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyOUWwNVYoRjJ2MEm1NFE3RC:jPh?=
MCF7 NGrrXYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3Sx[|Q5KGh? NGTBS3FIUT1yLkS1JO69VQ>? NWSyXZQ6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSxNVk2PTVpPkK0NVE6PTV3PD;hQi=>
MDA-MB-435 MYPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M1HselQ5KGh? MV7HTV0xNjh6IN88US=> NXnwd|hMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSxNVk2PTVpPkK0NVE6PTV3PD;hQi=>
AsPC1 NWjodFN6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnvYN|Ah|ryP MUe0PEBp Moi2SG1UVw>? MXvJR|UxRTNwNk[g{txO M4DiVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MUi1N|c5Lz5{NEG4OVM4QDxxYU6=
Jurkat E6.1 NHL0fVRMcW6jc3WgRZN{[Xl? MWCyJIg> NXjObHRVTE2VTx?= NGfKVplKdmirYnn0bY9vKG:oIFjERWM1KHerdHigTWM2OCCxZjCwMlA1KM7:TR?= NH7m[mc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEK2NVg3Oid-MkSyOlE5PjJ:L3G+
KG1 NWPYdVFyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUHab4hqPDhiaB?= Mne4TWM2OD1zLkG1JO69VQ>? NVfseYY{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS1NlUxODNpPkK0OVI2ODB|PD;hQi=>
HEL NEP4e3pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1;GN|Q5KGh? NFnDR4NFVVOR MnmwTWM2OD1yLkS5JO69VQ>? NYjrVZFORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS2PVQxPTVpPkK0Olk1ODV3PD;hQi=>
HSC3 M{Xh[mN6fG:2b4jpZ{BCe3OjeR?= NGezPI8yOiCq NWDH[HlmTE2VTx?= NX7pPFRnUUN3ME2wMlcyKM7:TR?= MorMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5Nk[1OlAoRjJ2N{[2OVYxRC:jPh?=
HT-29 NG\yWI5EgXSxdH;4bYMhSXO|YYm= NXPyN|FsOTJiaB?= NUPEVIhSTE2VTx?= MYnJR|UxRTBwN{Kg{txO NYjjUWo4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3OlY2PjBpPkK0O|Y3PTZyPD;hQi=>
KB NVrqfmZCS3m2b4TvfIlkKEG|c3H5 NEPHdJUyOiCq NEDNWWVFVVOR MnzZTWM2OD1yLke1JO69VQ>? MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd4NkW2NEc,OjR5Nk[1OlA9N2F-
H460 M1\UN2N6fG:2b4jpZ{BCe3OjeR?= M37tRVEzKGh? MlHlSG1UVw>? MUnJR|UxRTBwOEKg{txO Mlz5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5Nk[1OlAoRjJ2N{[2OVYxRC:jPh?=
MONE1 NWXxdGlVS3m2b4TvfIlkKEG|c3H5 NX;BSVVoOTJiaB?= NV;SPIExTE2VTx?= NX\uRWpjUUN3ME2xMlE5KM7:TR?= NFjpcmQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEe2OlU3OCd-MkS3OlY2PjB:L3G+
MKN45 NEDsW2JEgXSxdH;4bYMhSXO|YYm= NY\0fWlpOTJiaB?= NX;BU5VJTE2VTx?= MmfyTWM2OD1zLkK1JO69VQ>? NX7HNJJSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3OlY2PjBpPkK0O|Y3PTZyPD;hQi=>
TSGH M{H0SmN6fG:2b4jpZ{BCe3OjeR?= MnrxNVIhcA>? MnfDSG1UVw>? NX65Unp1UUN3ME2yMlA6KM7:TR?= M2ftXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{[2OVYxLz5{NEe2OlU3ODxxYU6=
HL60 Ml3nS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NITIZos4OiCq M4fhcWROW09? MorNS2k2OD1yLkmzJO69VQ>? NEizcVg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEmwNFUxOCd-MkS5NFA2ODB:L3G+
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