Vorinostat (SAHA)

For research use only. Not for use in humans.

製品コードS1047 別名:MK0683

Vorinostat (SAHA)化学構造

CAS No. 149647-78-9

Vorinostat (suberoylanilide hydroxamic acid, SAHA, MK0683) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay. Vorinostat abrogates productive HPV-18 DNA amplification.

サイズ 価格(税別) 在庫  
10mM (1mL in DMSO) JPY 33700 あり
JPY 16000 あり
JPY 26400 あり
JPY 38500 あり
最寄りの販売代理店を探す

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バルク問合せ

文献中Selleckの製品使用例(384)

製品安全説明書

HDAC阻害剤の選択性比較

生物活性

製品説明 Vorinostat (suberoylanilide hydroxamic acid, SAHA, MK0683) is an HDAC inhibitor with IC50 of ~10 nM in a cell-free assay. Vorinostat abrogates productive HPV-18 DNA amplification.
ターゲット
HDAC [1]
(Cell-free assay)
~10 nM
体外試験

Vorinostat inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively. Vorinostat also results in a marked hyperacetylation of histone H4. [1] Vorinostat inhibits the growth of three prostate cancer cell lines LNCaP, PC-3 and TSU-Pr1 at micromolar concentrations (2.5-7.5 μM), and induces dose-dependent cell death in LNCaP cells. [2] Vorinostat treatment in MCF-7 cells inhibits cell proliferation at an IC50 of 0.75 μM resulting in the accumulation of cells in the G1 and G2-M phase of the cell cycle. Vorinostat also induces differentiation in the estrogen receptor-negative cell line SKBr-3 and the retinoblastoma-negative cell line MDA-468. [3] Vorinostat treatment at 1 μM for 8 hours or more is sufficient to irreversibly induce apoptosis of human multiple myeloma (MM) cells. The gene expression profiles of Vorinostat treated MM cells are not hallmarked by global transcriptional activation, but by coordinated transcriptional changes of specific functional groups of genes such as cytokine-induced proliferative/survival signaling cascades, oncogenes-tumor suppressor genes, regulators of apoptosis, DNA synthesis-repair and cell cycle, and proteasome-ubiquitin function. [4]

細胞データ
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
H1299 M2DQZ2tqdmG|ZTDBd5NigQ>? NHP4NGozOCCvaX6= MYTEUXNQ MlHPTY5pcWKrdH;yfUBi[3Srdnn0fUBi\2GrboP0JGhFSUNiZX76fY1mKHerdHigTWM2OCCxZjCwMlE6PCEQvF2= NEjmXWE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEWyNVQzOid-MUS1NlE1OjJ:L3G+
HT1080 NHL0elJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NU\mO3ZVPzJiaB?= NXG2V484TE2VTx?= NFfVfG1KSzVyPUKuOEDPxE1? NEmwXnQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkK3NFE4PSd-MUKyO|AyPzV:L3G+
K562 MmiyT4lv[XOnIFHzd4F6 NH7md|A3KGh? M3zFUGROW09? M2W4[mlvcGmkaYTpc44hd2ZiaIXtZY4hcGm|dH;u[UBl\WGlZYT5cIF{\SBqbXn4eJVz\SCxZjDISGFEOSCjbnSgTGRCSzJrIIfpeIghUUN3MDDv[kAxNjBzIN88US=> NEnVfY49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkSxPVM5OCd-MUK0NVk{QDB:L3G+
A20 NFfi[5BMcW6jc3WgRZN{[Xl? NYfN[2JCOSCq MX;EUXNQ NYXJfo9Y[W62aT3ISGFEOSCjY4Tpeol1gSC5aYToJGlEPTBib3[gNE4yOTJizszN MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTl4MES4PUc,OTF7NkC0PFk9N2F-
Friend leukemic cell MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MmqwOVAh|ryP M1n3RVczKGh? NXL6fFVxTE2VTx?= NUn1Wpp7UUN3ME2wMlk6KM7:TR?= NEXod489[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkGwPVkyOyd-MUKxNFk6OTN:L3G+
H1299 M1zPfWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2\wcFczKGh? NUjaNop[TE2VTx?= M3\0XGlEPTB;Nz6yOEDPxE1? NHexN4g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEWyNVQzOid-MUS1NlE1OjJ:L3G+
HeLa NXHwXpN7U2mwYYPlJGF{e2G7 NH;aTII{OCCvaX6= MnrZTY5pcWKrdH;yfUBkd26lZX70doF1cW:wIHHnZYlve3RiaHnzeI9v\SCmZXHj[ZR6dGG|ZTD3bZRpKEmFNUCgc4YhOC5{ODFOwG0> NXnWbmZLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW2NFM6PDlpPkG1OlA{QTR7PD;hQi=>
LOX-IMVI MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NVLRU5lJPDhiaB?= NF:2PIRKSzVyPUGuN{DPxE1? M{fFV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{G1OFcxLz5zNUexOVQ4ODxxYU6=
NCI-H226 NXXVe2t4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXS0PEBp MVvJR|UxRTJwNjFOwG0> MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTdzNUS3NEc,OTV5MUW0O|A9N2F-
RXF-631L NVHydIxpT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2XlWlQ5KGh? MlXZTWM2OD1{IN88US=> NY[wOVNbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3NVU1PzBpPkG1O|E2PDdyPD;hQi=>
SNB-78 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NHzXU4I1QCCq M3f1TmlEPTB;MU[g{txO NV3W[HI6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3NVU1PzBpPkG1O|E2PDdyPD;hQi=>
St-4 NGfKZ2VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MlfqOFghcA>? MmqzTWM2OD13LkKg{txO M3PFTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{G1OFcxLz5zNUexOVQ4ODxxYU6=
ARP1 NYHVbYtOTnWwY4Tpc44hSXO|YYm= MonjNkDPxE1? MnPoOkBp NHnvNpFKdmS3Y4Tpc44hd2ZiUEKxW2FHOSCpZX7lJIV5eHKnc4Ppc44> M3qxSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF2N{O0PFA3Lz5zNEezOFgxPjxxYU6=
CEM M4DlPWtqdmG|ZTDBd5NigQ>? NWS1TVQ6OSCq MorySG1UVw>? MnW3TY5pcWKrdHnvckBw\iCKRFHDJJdqfGhiSVO1NEBw\iByLkOzJO69VQ>? MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjR{MEC2OEc,OTZ2MkCwOlQ9N2F-
HCT15 M1f0[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NF7ldYU1QCCq M13obGdKPTB;MD64NkDPxE1? MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjd{M{KyO{c,OTZ5MkOyNlc9N2F-
NCI-H23 MlmzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{D2b|Q5KGh? MmWwS2k2OD1yLkmyJO69VQ>? NGPHVmM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkeyN|IzPyd-MU[3NlMzOjd:L3G+
GM15850 NX7VdVVkU2mwYYPlJGF{e2G7 NYi2e41SOi53IN88US=> MkH6PVYhcA>? NY\0PYxSTE2VTx?= M37Hd2lvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFizJIx6e2mwZTCxOEBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= M{PzPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4OUKxN|Y4Lz5zNkmyNVM3PzxxYU6=
GM15850 MWTLbY5ie2ViQYPzZZk> NGXufXozNjVizszN MlzrPVYhcA>? MXfEUXNQ MkO5TY5pcWKrdHnvckBw\iCKRFHDJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIHjpd5RwdmViSESgcJl{cW6nIEWgZYNmfHmuYYTpc44hd2ZiRmjOJIdmdmV? NITDWXk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkmyNVM3Pyd-MU[5NlE{Pjd:L3G+
GM15850 M4DkUmtqdmG|ZTDBd5NigQ>? NXvnNYlLOi53IN88US=> MUO5OkBp NFrTUFlFVVOR M{jWemlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFi0JIx6e2mwZTCxNkBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= MnHzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ7MkGzOlcoRjF4OUKxN|Y4RC:jPh?=
GM15850 NHnvR3BMcW6jc3WgRZN{[Xl? MnPaNk42KM7:TR?= M1LkWlk3KGh? NFnkcnZFVVOR MXTJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhcW6lcnXhd4UhcW5iaHnzeI9v\SCKMzDsfZNqdmViOTDhZ4V1gWyjdHnvckBw\iCIWF6g[4Vv\Q>? NIDGR2E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkmyNVM3Pyd-MU[5NlE{Pjd:L3G+
GM15850 NH\R[ZRMcW6jc3WgRZN{[Xl? NYrHZZpQOi53IN88US=> NHu4V4o6PiCq NIexWYVFVVOR NXfhb3E6UW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJIhqe3SxbnWgTFQhdHm|aX7lJFgh[WOndInsZZRqd25ib3[gSnhPKGenbnW= MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjl{MUO2O{c,OTZ7MkGzOlc9N2F-
GM15850 NVLIOmp[U2mwYYPlJGF{e2G7 MUSyMlUh|ryP MVO5OkBp MmG2SG1UVw>? M3vT[WlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIFi0JIx6e2mwZTCxOkBi[2W2eXzheIlwdiCxZjDGXG4h\2WwZR?= MnSxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ7MkGzOlcoRjF4OUKxN|Y4RC:jPh?=
U937 NG\M[IpHfW6ldHnvckBCe3OjeR?= NULWTVNiPSEQvF2= MnvSNlQhcA>? NInqc4JFVVOR M12xUmNmdGxiY4njcIUh[XK{ZYP0JIJ6KGGlY4XteYxifGmxbjDheEBUN0d{L12gdIhie2V? M13aeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MEC0O|E5Lz5zN{CwOFcyQDxxYU6=
H661 M1uzb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1nCZ|Q5KGh? Mm\0TWM2OD1zIN88US=> MkTUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzNUewNFkoRjF5MUW3NFA6RC:jPh?=
U937 NIjzZnBHfW6ldHnvckBCe3OjeR?= NIPQcJo2KM7:TR?= MX:yOEBp M4XnZmROW09? NV\Sd|g{UW6lcnXhd4UhcW5iaHnzeI9v\SCKMzDhZ4V1gWyjdHnvci=> NFG0RlE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S0O|c2OCd-MUe0OFc4PTB:L3G+
U937 MWjGeY5kfGmxbjDBd5NigQ>? MXWxJO69VQ>? M2PaZ|I1KGh? NVnsfVNTTE2VTx?= MWrF[oZm[3Rib36gZYxxcGFidIXieYxqdiCjY3X0fYxifGmxbh?= NWfaNFcyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFc4PTBpPkG3OFQ4PzVyPD;hQi=>
RAW264.7 MlriSpVv[3Srb36gRZN{[Xl? NVn0VZY6OTBizszN MmPmNlRp MYj3ZZRmeg>? NGL2cWJKdmirYnn0bY9vKG:oIFzQV{1{fGmvdXzheIVlKFSQRnHsdIhiKHC{b3T1Z5Rqd25id3n0bEBKSzVyIH;mJFAvPzZizszN NF[4V4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S3O|UyQCd-MUe0O|c2OTh:L3G+
RAW264.7 MXPGeY5kfGmxbjDBd5NigQ>? M4fnXFExKM7:TR?= NH7vWIMzPGh? NGj4WJJ4[XSnch?= NYq1[JRDUW6qaXLpeIlwdiCxZjDMVHMue3SrbYXsZZRm\CCQTzDwdo9lfWO2aX;uJJdqfGhiSVO1NEBw\iBzLki4JO69VQ>? M{DGc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEe3OVE5Lz5zN{S3O|UyQDxxYU6=
SC9 NGixT3dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjyOFghcA>? MoTaTWM2OD1yLk[wOkDPxE1? NUfnZopPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1NFczOTlpPkG3OVA4OjF7PD;hQi=>
ST14A MWjGeY5kfGmxbjDBd5NigQ>? NH\nR4s2KG6P MoW5O|IhcA>? M1\HTWlv[3KnYYPlJIlvKFKHU2SvUnJUTiCvUl7BJIV5eHKnc4Ppc44> M4j3[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NU[1PVk{Lz5zN{W2OVk6OzxxYU6=
ST14A M2e4T2Z2dmO2aX;uJGF{e2G7 M1nKOVUhdk1? NYGzOYh{PzJiaB?= MlHqTY5kemWjc3WgbY4hTTKIMTDtVm5CKGW6cILld5Nqd25? NVm4[ldvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1OlU6QTNpPkG3OVY2QTl|PD;hQi=>
PANC1 NVq5dXJIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NYn5OpE{OSEQvF2= MXjJR|UxRTBwNEWg{txO MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV6OEe0OEc,OTd3OEi3OFQ9N2F-
PANC1 NVm5PXdkTnWwY4Tpc44hSXO|YYm= NEXKbFIyKM7:TR?= NYDZRohCOjRiaB?= M3u3S2lv[3KnYYPlJIlvKHB{MWfBSlEwS0mSMTDn[Y5mKGW6cILld5Nqd25? M1:0NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUi4O|Q1Lz5zN{W4PFc1PDxxYU6=
PANC1 NEXnbXJHfW6ldHnvckBCe3OjeR?= MU[xJO69VQ>? NIHT[XkzPCCq NVvYT|I4UW6lcnXhd4UhcW5icEK3b4lxOSCpZX7lJIV5eHKnc4Ppc44> MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV6OEe0OEc,OTd3OEi3OFQ9N2F-
PT45 NYXCXFdvT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NEWxUJBKSzVyPUSg{txO MmfKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3OEi3OFQoRjF5NUi4O|Q1RC:jPh?=
ACHN MYXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mlu1NlEhcA>? NUDlO|N1T0l3ME2wMlY2KM7:TR?= NWfWenI3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2OlI3ODZpPkG3OlYzPjB4PD;hQi=>
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A431 M2jTfWN6fG:2b4jpZ{BCe3OjeR?= MX63NkBp M{nTbWlEPTB;ND6yJO69VQ>? MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7MUe2N{c,OTd4OUG3OlM9N2F-
Cal27 MlfSR5l1d3SxeHnjJGF{e2G7 MWO3NkBp NIf2RWxKSzVyPUOuNkDPxE1? NWT2Vnc2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVE4PjNpPkG3OlkyPzZ|PD;hQi=>
CCRF-CEM MVnDfZRwfG:6aXOgRZN{[Xl? NEjpbnc4OiCq Ml;VTWM2OD1yLkig{txO M3\kclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NkmxO|Y{Lz5zN{[5NVc3OzxxYU6=
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CAL27 M{TMdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2rWclczKGh? NGixc5pKSzVyPUOuO|Ih|ryP NXjmSodqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCxOFM4PzhpPkKwNVQ{Pzd6PD;hQi=>
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SKHEP1 MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NWn6[5drPzJiaB?= MWPJR|UxRTNwNE[g{txO NUm1cJF7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCxOFM4PzhpPkKwNVQ{Pzd6PD;hQi=>
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Caco-2 M3e4WGtqdmG|ZTDBd5NigQ>? NYnBVFllPi5|MjDuUUB1dyB4M{Kg{txO M4fyXVQhcA>? MoqzSG1UVw>? MlqwSZghfmm4bzDpcohq[mm2aX;uJI9nKGi3bXHuJGhFSUN5IIfpeIghUUN3MDDv[kA1OSEQvF2= MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODF2M{i0NEc,OjBzNEO4OFA9N2F-
Caco-2 Mnu3T4lv[XOnIFHzd4F6 NVO4b5Y{OC5|MU[gcm0hfG9iM{GuOkDPxE1? NWWyU4ZQPCCq M4O5NGROW09? NXW1fY1VTXhidnn2c{BqdmirYnn0bY9vKG:oIHj1cYFvKEiGQVO2 NXj5emw{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkCxOFM5PDBpPkKwNVQ{QDRyPD;hQi=>
HepG2 MU\LbY5ie2ViQYPzZZk> MWi1JO69VQ>? MYm2bC=> NHzLOmpFVVOR NGfYS|NKdmS3Y4Tpc44hd2ZiSFTBR{1u\WSrYYTl[EBpcXO2b37lJIFk\XS7bHH0bY9v Mn35QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjBzNEO4OFAoRjJyMUSzPFQxRC:jPh?=
HepG2 NHf5ZnZMcW6jc3WgRZN{[Xl? MUC1JO69VQ>? NGmwN3U3cA>? M2fFV2ROW09? NIToS49KdmS3Y4Tpc44hd2ZiSFTBR{1u\WSrYYTl[EBpcXO2b37lJIh6eGW{YXPleJlt[XSrb36= MnrWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjBzNEO4OFAoRjJyMUSzPFQxRC:jPh?=
HepG2 MkHIT4lv[XOnIFHzd4F6 M3\aRlUh|ryP M2jlVlZp NH7CXHFFVVOR NVizSmpWUW6mdXP0bY9vKG:oIFjERWMudWWmaXH0[YQh[WyyaHGteJVjfWyrbjDhZ4V1gWyjdHnvci=> M4jRU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyMUSzPFQxLz5{MEG0N|g1ODxxYU6=
HepG2 MoTrT4lv[XOnIFHzd4F6 NYHNVIx7PSEQvF2= NFvWU4E3cA>? MYHEUXNQ NInkeYhKdmS3Y4Tpc44hd2ZiSFTBR{1u\WSrYYTl[EBJOy:KNDDobZN1d26nIHHj[ZR6dGG2aX;u NHvaU5A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEG0N|g1OCd-MkCxOFM5PDB:L3G+
COLO205 M3fpNWtqdmG|ZTDBd5NigQ>? MVWxNEDPxE1? NF62[mwzPCCq NHnNdFRFVVOR MYfJcohq[mm2aX;uJI9nKEiGQVOxJIF{e2W|c3XkJIF{KGmwZIXjeIlwdiCxZjDobZN1d26nIFizJIFk\XS7bHH0bY9vKHerdHigTWM2OCCxZjCyMlIh|ryP NVTnNpIzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0OVE{PzhpPkKwOFUyOzd6PD;hQi=>
SCC4 NYnlUVIxU2mwYYPlJGF{e2G7 MUOxJO69VQ>? M4C4ZlI1cA>? MlXmTY5pcWKrdHnvckBw\iCKRFHDJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIIT1ZpVtcW5iYXPleJlt[XSrb36= NULITpg1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0OVIzOjVpPkKwOFUzOjJ3PD;hQi=>
SCC4 NGDLT3VMcW6jc3WgRZN{[Xl? NX7mPWxIOSEQvF2= NYXQfmZ6OjSq M3TE[mlvcGmkaYTpc44hd2ZiSFTBR{Bie3Onc4Pl[EBieyCrbnPy[YF{\SCrbjDobZN1d26nIHHj[ZR6dGG2aX;u MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODR3MkKyOUc,OjB2NUKyNlU9N2F-
SCC4 M4DvXWZ2dmO2aX;uJGF{e2G7 M17jbVEh|ryP MYW1JI1qdg>? MXjB[49vcXO2IHHjeIl3cXS7IHH0JHZFWiCjc4Pld5Nm\CCjczDpcoR2[3Srb36gc4YhS1mSMkSg[4Vv\SCneIDy[ZN{cW:w M3PJZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyNEWyNlI2Lz5{MES1NlIzPTxxYU6=
NB4 NUHMU|hKTnWwY4Tpc44hSXO|YYm= M4DROlUh|ryP MV[yOEBp M3LiXWROW09? MYfD[YxtKGO7Y3zlJIFzemW|dDDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCjY3P1cZVt[XSrb36gZZQheHKnLVexJJBp[XOn NUfOcIRpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0PVE1PDBpPkKwOFkyPDRyPD;hQi=>
NB4 M{D4PWtqdmG|ZTDBd5NigQ>? M1vVe|Uh|ryP MVKyOEBp M1fwcGROW09? MmHLTY5pcWKrdHnvckBw\iCKRFHDJIF{e2W|c3XkJIF{KGmwY4LlZZNmKGmwIHHj[ZR6dGG2ZTD0eYJ2dGmwIHzleoVt NGXNU5I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MES5NVQ1OCd-MkC0PVE1PDB:L3G+
NB4 NUPlRZFCTnWwY4Tpc44hSXO|YYm= NHnvV5g2KM7:TR?= M2XFRlI1KGh? NXTubXU5TE2VTx?= MlPUTY5lfWO2aX;uJI9nKHB{MWfBSlEwS0mSMTDlfJBz\XO|aX;u MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODR7MUS0NEc,OjB2OUG0OFA9N2F-
NB4 M1;aOGtqdmG|ZTDBd5NigQ>? MVm1JO69VQ>? NED4TXMzPCCq M1;YSWROW09? NH;oSmdKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaX7jdoVie2ViaX6gbIl{fG:wZTDIN{Bi[2W2eXzheIlwdg>? NYWwcFB2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC0PVE1PDBpPkKwOFkyPDRyPD;hQi=>
NUGC3 NGPaNldIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnjyS2k2OD1{Lkm0JO69VQ>? NXrQ[YhFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4OVA6PzFpPkKwPFUxQTdzPD;hQi=>
A549 Moe0SpVv[3Srb36gRZN{[Xl? NHvtSGE2KM7:TR?= NGT3SWs{KGh? Mn\0SG1UVw>? MmS3TY5lfWO2aX;uJI9nKGG3dH;wbIFogSCrbjDoeY1idiCDNUS5JINmdGy|IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKEyFM1nJ Mkf0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6NUWyNFgoRjJyOEW1NlA5RC:jPh?=
HUT78 NGXIOYRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{PWbVczKGh? MWXEUXNQ NXT3UVU6T0l3ME2wMlMh|ryP MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODh6NEKwPEc,OjB6OESyNFg9N2F-
U937 NE\ac3ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MoKyO|IhcA>? MkPLSG1UVw>? NVr3R5A3T0l3ME2wMlM6KM7:TR?= NWPpOplvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4PFQzODhpPkKwPFg1OjB6PD;hQi=>
A431 MVHDfZRwfG:6aXOgRZN{[Xl? M3PieFczKGh? NIDIfWNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPDNzIHPlcIx{KG:4ZYLlfJBz\XO|aX7nJGVITlJid3n0bEBKSzVyIH;mJFQvOiEQvF2= NIH0[lE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC4NFYzQSd-MkGwPFA3Ojl:L3G+
A549 NUXkbXVpS3m2b4TvfIlkKEG|c3H5 NUD4eGM2PzJiaB?= NGHwR5hEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KG:4ZYLlfJBz\XO|aX7nJGhFSUNid3n0bEBKSzVyIH;mJFEvQCEQvF2= NXjYbZF4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwPFA3OjlpPkKxNFgxPjJ7PD;hQi=>
CAL27 NEm2XmFEgXSxdH;4bYMhSXO|YYm= MU[3NkBp MkK1R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gR2FNOjdiY3XscJMhd3[ncnX4dJJme3OrbnegSWdHWiC5aYToJGlEPTBib3[gN{4zKM7:TR?= NX20U|Y3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwPFA3OjlpPkKxNFgxPjJ7PD;hQi=>
HeLa NWGxT3hXS3m2b4TvfIlkKEG|c3H5 M3jPZVczKGh? Mk\UR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVN[SClZXzsd{BwfmW{ZYjwdoV{e2mwZzDISGFEKHerdHigTWM2OCCxZjCxMlUh|ryP M2DpNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEiwOlI6Lz5{MUC4NFYzQTxxYU6=
Sf21 MWPLbY5ie2ViQYPzZZk> NYrlNVB1OyCq NFHISHJKdmirYnn0bY9vKG:oIF\sZYchfGGpZ3XkJIh2dWGwIILlZ49u[mmwYX70JGhFSUN6IHX4dJJme3OnZDD3bZRpKEmFNUCgc4YhOS5{IN88US=> M4flZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEiwOlI6Lz5{MUC4NFYzQTxxYU6=
SKBR3 MoXWR5l1d3SxeHnjJGF{e2G7 MVW3NkBp NWDyOYpZS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0uEUkOgZ4VtdHNib4\ldoV5eHKnc4PpcochUEWUMjD3bZRpKEmFNUCgc4YhOi54IN88US=> NFHVPYk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC4NFYzQSd-MkGwPFA3Ojl:L3G+
SKOV3 NFTqPIZEgXSxdH;4bYMhSXO|YYm= MUO3NkBp NU\HO3hCS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hW0uRVkOgZ4VtdHNib4\ldoV5eHKnc4PpcochUEWUMjD3bZRpKEmFNUCgc4YhOi5{IN88US=> MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB6ME[yPUc,OjFyOEC2Nlk9N2F-
COR-L23 MmnCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUTDOmNSOTBizszN MUW3NkBp M2\BXmROW09? M3nBXmdKPTB;MT6xJO69VQ>? NV3kSmZ[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwPFA3PDdpPkKxNFgxPjR5PD;hQi=>
DU145 MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWCxNEDPxE1? MXq3NkBp M2C1T2ROW09? M4THfmdKPTB;MT6wOUDPxE1? M3rPUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMEiwOlQ4Lz5{MUC4NFY1PzxxYU6=
LoVo MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEH5XoQyOCEQvF2= NUnLcY5QPzJiaB?= M1vGOGROW09? Mn7XS2k2OD1zLkeg{txO NHnJVWc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC4NFY1Pyd-MkGwPFA3PDd:L3G+
MCR5-SV2 MnWxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVexNEDPxE1? MV[3NkBp NEDaeGRFVVOR Mne5S2k2OD1{LkGg{txO Ml3MQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyOEC2OFcoRjJzMEiwOlQ4RC:jPh?=
HCT116 NEDt[FVMcW6jc3WgRZN{[Xl? MlnjN|Ah|ryP MWezNEBp NWfQb3FFTE2VTx?= MkjLTY5pcWKrdHnvckBw\iCKRFHDOkBie3Onc4Pl[EBieyCrbnT1Z5Rqd25ib3[gZYxxcGFvdIXieYxqdiCjY3X0fYxifGmxbh?= NUjnOGY1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwPFA3PDdpPkKxNFgxPjR5PD;hQi=>
HCT116 NV;YTFNOU2mwYYPlJGF{e2G7 MWOzNEDPxE1? NFuwVZA{OCCq NFG0ZmtFVVOR MXjJcohq[mm2aX;uJI9nKEiGQVOxJIF{e2W|c3XkJIF{KGmwZIXjeIlwdiCxZjDobZN1d26nIFizT|kh[WOndInsZZRqd25? MnjoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFyOEC2OFcoRjJzMEiwOlQ4RC:jPh?=
U937 NEXqc5hMcW6jc3WgRZN{[Xl? MofvOUDPxE1? NI\4cnozPCCq NXGxWYlRTE2VTx?= MXvJcohq[mm2aX;uJI9nKGirc4TvcoUh[WOndInseJJidnOoZYLhd4Uh[XO|ZYPz[YQh[XNiaX7jdoVie2Vib3[gZYNmfHmuYYTpc44hd2ZiaHnzeI9v\SCKMzDheEBMQQ>? MkfXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{OUK0PVIoRjJzMkmyOFkzRC:jPh?=
U937 Mme2T4lv[XOnIFHzd4F6 M4HBPFUh|ryP MkHyNlQhcA>? MXXEUXNQ MXzJcohq[mm2aX;uJI9nKGirc4TvcoUh[WOndInseJJidnOoZYLhd4Uh[XO|ZYPz[YQh[XNiaX7jdoVie2Vib3[gZYNmfHmuYYTpc44hd2ZiaHnzeI9v\SCKMzDheEBMOTh? NGDifWw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5NlQ6Oid-MkGyPVI1QTJ:L3G+
U937 MVPLbY5ie2ViQYPzZZk> NEfPXYw2KM7:TR?= NWjOVXVHOjRiaB?= M3PUemROW09? MYDJcohq[mm2aX;uJI9nKGirc4TvcoUh[WOndInseJJidnOoZYLhd4Uh[XO|ZYPz[YQh[XNiaX7jdoVie2Vib3[gdIFvNWGlZYT5cIF1\WRiaHnzeI9v\SCKNDDs[ZZmdA>? MlKyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{OUK0PVIoRjJzMkmyOFkzRC:jPh?=
U937 Mon6T4lv[XOnIFHzd4F6 M3n1NFUh|ryP NFXzNlEyPSCvaX6= NXHuXZl4TE2VTx?= M4XDN2lvcGmkaYTpc44hd2ZiaHnzeI9v\SCjY3X0fYx1emGwc3\ldoF{\SCjc4Pld5Nm\CCjczDpcoNz\WG|ZTDv[kBpcXO2b37lJGg{KGGlZYT5cIF1cW:wIHzleoVt NUnSeppiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGyPVI1QTJpPkKxNlkzPDl{PD;hQi=>
A2780 NFTFZXVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M1izcFk3KGh? NXH4e2cxTE2VTx?= MXPJR|UxRTFwNkKg{txO NYLrb3dnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG2N|Q1OzBpPkKxOlM1PDNyPD;hQi=>
COLO205 M2qzRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIfU[3I6PiCq MUXEUXNQ NGP0NVBKSzVyPUKuNVIh|ryP MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTZ|NESzNEc,OjF4M{S0N|A9N2F-
Hep3B MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4\iXFQ5KGh? MULEUXNQ MmnzS2k2OD1zLkKxJO69VQ>? MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTdzMkG0Okc,OjF5MUKxOFY9N2F-
GM11272 NGnGWZZHfW6ldHnvckBCe3OjeR?= MkfzNVAxKG6P MV23NkBp NFL3bFBFVVOR NEX2RpdT\WGldHn2ZZRqd25ib3[gUYVEeDJibYX0ZY51KGW6cILld5Nqd25iYYSgNVAhfG9iMUCwJI5O NHrpSGE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi0NFcyPid-MkG4OFA4OTZ:L3G+
CFBE41o NYrxS4gzU2mwYYPlJGF{e2G7 M1vhUlUh|ryP MYPEUXNQ MkXGSI94diC{ZXf1cIF1cW:wIH;mJGhFSUN5IHH0JFAvOiC2bzC1JJVO M{fENVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOUi0PVU5Lz5{MUm4OFk2QDxxYU6=
CFBE41o NG\SZ5pHfW6ldHnvckBCe3OjeR?= MWexJO69VQ>? M1;2XVI1KGh? NYH3dWFWTE2VTx?= MXjS[ZN1d3KjdHnvckBw\iCFRmTSJIRmdHSjRkWwPEBufXSjboSgeJJi\m[rY3vpcochfG9iY3XscEB{fXKoYXPlJIF{KGeueXPv[o9zdXN? MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl6NEm1PEc,OjF7OES5OVg9N2F-
DU145 NGjl[IJMcW6jc3WgRZN{[Xl? MXSyMlUh|ryP NXvnTHlqOjRiaB?= MkHBSG1UVw>? MWHJcohq[mm2aX;uJI9nKEiGQVOgZZN{\XO|ZXSgZZMhfXC{ZXf1cIF1cW:wIH;mJJAzOXejZkGgdJJwfGWrbjDlfJBz\XO|aX;u NUXF[HNJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKyOlAyPjZpPkKyNlYxOTZ4PD;hQi=>
DU145 MojKT4lv[XOnIFHzd4F6 MlfIOUDPxE1? MXSyOEBp MX\EUXNQ NVfq[5M4UW6qaXLpeIlwdiCxZjDISGFEKGG|c3Xzd4VlKGG|IHjpd5RwdmViSESgZYNmfHmuYYTpc44> NEjDc5U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkK2NFE3Pid-MkKyOlAyPjZ:L3G+
DU145 NV;UUZRUU2mwYYPlJGF{e2G7 NWnYcFFTPSEQvF2= NYLCXXVYOjRiaB?= M3TYUWROW09? NGnSSlZKdmirYnn0bY9vKG:oIFjERWMh[XO|ZYPz[YQh[XNiaHnzeI9v\SCKMzDofZBmemGlZYT5cIF1cW:w NXPpXXFKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKyOlAyPjZpPkKyNlYxOTZ4PD;hQi=>
786-0 MkHES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M2\oc|YvOiEQvF2= M{n6XVczKGh? MVXEUXNQ NV;ifopJT0l3ME2zMlIh|ryP Ml\UQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
A498 MnrkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NFW1SGU3NjJizszN NE\JV244OiCq MkfTSG1UVw>? NUjZV3ZlT0l3ME2xMlYh|ryP NGLROHQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
A549/ATCC NIXiNGZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MXe2MlIh|ryP NGf5OII4OiCq MXTEUXNQ MoD4S2k2OD1zLk[g{txO MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
ACHN NUizSJEzT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{LLcVYvOiEQvF2= MXK3NkBp M1PxN2ROW09? NUH0[Jg4T0l3ME2xMlMh|ryP NH\YOVU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
BT549 NGrXW|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NWTR[lh6Pi5{IN88US=> M13jVFczKGh? NYmwRWlQTE2VTx?= NYrFTGNNT0l3ME2xMlMh|ryP MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
EKVX MoPBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NVvFNIRzPi5{IN88US=> NFm3[5U4OiCq NIH1PHhFVVOR NFrQWpNIUTVyPUGuN{DPxE1? NXnl[Hd4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
HCT15 Mnj2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NIPPNnE3NjJizszN M4rNW|czKGh? MlrjSG1UVw>? MnPCS2k2OD1{LkWg{txO MoXhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
HOP92 MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NFfCPGk3NjJizszN NX:0cFNEPzJiaB?= NEnoNXdFVVOR MV;HTVUxRTRizszN M{DMZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
IGROV1 NGj3Tm5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVG2MlIh|ryP NH3vWG44OiCq NYHYSGxVTE2VTx?= MmLPS2k2OD1zLkOg{txO NH7NNWI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
LOXIMVI NUXTdo5LT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NW\lNXJ2Pi5{IN88US=> NYfHTHI1PzJiaB?= MoezSG1UVw>? M4nGd2dKPTB;MTFOwG0> NY\1TXJkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
M14 MoXzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGrt[XQ3NjJizszN NXHPOoluPzJiaB?= MWTEUXNQ NVrmTWVwT0l3ME2xMlMh|ryP M3zVRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
MALME-3M NHv2U|NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mn;EOk4zKM7:TR?= M4nzc|czKGh? NV;6VHJFTE2VTx?= NUHlO4FrT0l3ME2wMlMzKM7:TR?= NYnHem9PRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
MCF10A Ml3jS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn3rOk4zKM7:TR?= MWe0PEBp MmPDSG1UVw>? M2nTV2dKPTB;OT62JO69VQ>? NW\1VVJnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
MDA-MB-435 MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MnXUOk4zKM7:TR?= MX:3NkBp MXPEUXNQ NWnLNFFFT0l3ME2wMlUh|ryP MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
MDA-MB-468 NUfYVZR7T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Mm\sOk4zKM7:TR?= MYe3NkBp NYrPT3J5TE2VTx?= Ml\GS2k2OD1yLk[zJO69VQ>? M{jlZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
MOLT4 NG\qOmNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3LMZVYvOiEQvF2= NEfWW5Q4OiCq Mmj1SG1UVw>? MoflS2k2OD1yLkSg{txO M2C2bFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
NCI-ADR-RES M3nOVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M1nQXFYvOiEQvF2= NX;CO21jPzJiaB?= NWTtWmd3TE2VTx?= M{LnRWdKPTB;MD6xOkDPxE1? M1XwN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
NCI-H23 NIHic3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MVK2MlIh|ryP NHnjNlA4OiCq M4jkdGROW09? NYXN[5I1T0l3ME2xJO69VQ>? M1ywT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
NCI-H322M NVG1PWJwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlvDOk4zKM7:TR?= MXe3NkBp MoT3SG1UVw>? NVTLT4d6T0l3ME2wMlc6KM7:TR?= NIDOc3U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
NCI-H460 MoPaS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUfV[HduPi5{IN88US=> NVnlNotlPzJiaB?= Mn3OSG1UVw>? MoLKS2k2OD1yLke5JO69VQ>? NEfrUYo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
NCI-H522 NYK2Z3llT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MoLqOk4zKM7:TR?= M{W4bVczKGh? NWLj[YJMTE2VTx?= MVfHTVUxRTBwNTFOwG0> MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
OVCAR3 NGHXPFJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkC3Ok4zKM7:TR?= MWi3NkBp MXLEUXNQ M2W4XWdKPTB;MT6zJO69VQ>? Mlq5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
OVCAR4 MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M{TkeFYvOiEQvF2= M{jXS|czKGh? NX;nPVRkTE2VTx?= MYXHTVUxRTRizszN NUeyNYZMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
OVCAR5 M{\Fcmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M4PnOVYvOiEQvF2= MoCzO|IhcA>? MX\EUXNQ NH72N3pIUTVyPUCuO|kh|ryP NHvnUWw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
OVCAR8 NXLoOnY6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M1PFbFYvOiEQvF2= NGCwb3k4OiCq NX;iT|R2TE2VTx?= MYLHTVUxRTBwNTFOwG0> NFfSZ5A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
RXF393 MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Ml\2Ok4zKM7:TR?= M1K1TVczKGh? NIrFWXdFVVOR MlTxS2k2OD1zLkOg{txO MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
SF268 NFS2R3pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MUC2MlIh|ryP NYTseXNkPzJiaB?= NVX0UnhtTE2VTx?= MoHRS2k2OD1zLk[g{txO NH7uR4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
SF295 NXuyVW1tT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NH\QT2M3NjJizszN NHrKfm84OiCq M3PrXmROW09? NEPIUphIUTVyPUGuOkDPxE1? Mm\jQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
SF539 MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NIfwWVk3NjJizszN MYK3NkBp NVLvPG96TE2VTx?= M2[wO2dKPTB;MjFOwG0> MnfkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
SK-MEL-2 Mk[0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYG2MlIh|ryP M4C0dVczKGh? MX;EUXNQ MkTkS2k2OD1zLkOg{txO NWLDRXo1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
SK-MEL-28 M4HS[Gdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NWmybFN6Pi5{IN88US=> MYq3NkBp MVvEUXNQ NHzrOm5IUTVyPUGg{txO NFzrbVA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
SK-MEL-5 MmHVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M{jTcFYvOiEQvF2= M17KXVczKGh? MVnEUXNQ MU\HTVUxRTBwNkOg{txO MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
SKOV3 NX\jT403T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NXnJS44yPi5{IN88US=> NFLrV5I4OiCq M2TqemROW09? MlriS2k2OD1zIN88US=> NFT4UmQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
SN12C M1nLRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGLEfJQ3NjJizszN M3q1clczKGh? MoLTSG1UVw>? NEnFfItIUTVyPUKg{txO NHzFR2k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkSzOVY3QSd-MkK0N|U3Pjl:L3G+
SNB19 M1zzWmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYrEfGlTPi5{IN88US=> NHLhd2Y4OiCq NFq0XGhFVVOR NELGboRIUTVyPUCuOlMh|ryP NYDvVpB3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0N|U3PjlpPkKyOFM2PjZ7PD;hQi=>
SNB75 Mo[yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NGjXSlE3NjJizszN NYjVXZVHPzJiaB?= M1HYcmROW09? NVWw[nE4T0l3ME2wMlc6KM7:TR?= M3[4SlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
SR MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MX:2MlIh|ryP MnrjO|IhcA>? NVO0b|NZTE2VTx?= MV7HTVUxRTBwNDFOwG0> M{T0T|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
T47D MojrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M4DU[VYvOiEQvF2= Mm\GO|IhcA>? NX3RfWFGTE2VTx?= NIq1cpNIUTVyPUCuOUDPxE1? MoWzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2M{W2OlkoRjJ{NEO1OlY6RC:jPh?=
TK10 NUnoSXpUT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M2rn[VYvOiEQvF2= MnvsO|IhcA>? NXO4cop5TE2VTx?= MXTHTVUxRTBwNkOg{txO MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
UACC257 MkP4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUn4NZRIPi5{IN88US=> M1e2RVczKGh? MYDEUXNQ MVnHTVUxRTBwNTFOwG0> M3zHUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
UACC62 M13hU2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MnvuOk4zKM7:TR?= M{jxdlczKGh? NUf1PJZWTE2VTx?= NXr4c5h5T0l3ME2wMlQh|ryP MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|NU[2PUc,OjJ2M{W2Olk9N2F-
UO31 MoDHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MYe2MlIh|ryP MVm3NkBp MUfEUXNQ NHuxWZdIUTVyPUCuOUDPxE1? M3TPblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEO1OlY6Lz5{MkSzOVY3QTxxYU6=
Hep3B NUnFW|hlT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXu0PEBp MlrySG1UVw>? NH3pO|BIUTVyPUCuOlkh|ryP MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR|OUi2N{c,OjJ2M{m4OlM9N2F-
BE(2)-C NGnQR4lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NH;VeYw4OiCq M{nPW2ROW09? MYfJR|cxRTJizszN MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl|MkOxOkc,OjJ7M{KzNVY9N2F-
Bel7402 NI[w[nRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFy1cpc4OiCq NE\OSWFFVVOR MlflS2k6OD1zNzFOwG0> NILkWXc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C2NVM4Pid-MkOwOlE{PzZ:L3G+
Bel7404 M17FSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MYi3NkBp MUnEUXNQ M{PTbGdKQTB;MUig{txO NGjNUWw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C2NVM4Pid-MkOwOlE{PzZ:L3G+
BGC823 NET5No9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= Mni0O|IhcA>? MVrEUXNQ MWLHTVkxRTdwNTFOwG0> MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzB4MUO3Okc,OjNyNkGzO|Y9N2F-
MGC803 Ml64S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MkDyO|IhcA>? NUH4fnVvTE2VTx?= NVryZmJbT0l7ME2xNE45KM7:TR?= M{GyXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|ME[xN|c3Lz5{M{C2NVM4PjxxYU6=
SGC7901 NUHBV2RkT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWC5PXdyPzJiaB?= MY\EUXNQ M3rsUGdKQTB;OT60JO69VQ>? NHi2VGQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C2NVM4Pid-MkOwOlE{PzZ:L3G+
SKHEP1 M1HoeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIT2TWQ4OiCq MXLEUXNQ NF\pelNIUTlyPUG3JO69VQ>? M362dVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|ME[xN|c3Lz5{M{C2NVM4PjxxYU6=
SMMC7721 NF\6WXpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXGyNoh{PzJiaB?= M1u5e2ROW09? NFXyOXlIUTlyPUKwJO69VQ>? NGPO[209[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{C2NVM4Pid-MkOwOlE{PzZ:L3G+
NUGC3 M4jnSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NGDDfpIyOCEQvF2= NYjEdJNuT0l;Mj65OEDPxE1? MnzFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNkOzN|IoRjJ|MU[zN|MzRC:jPh?=
A2780 CisR MWXLbY5ie2ViQYPzZZk> NEe5W2YyQCCq M3;oeGlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD60OEDPxE1? NUizVGtLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyOVI3ODNpPkKzNlUzPjB|PD;hQi=>
CAL27 sens NFvrT49McW6jc3WgRZN{[Xl? NWD6[HNWOThiaB?= MmOwTY5pcWKrdHnvckBw\iCKRFHDJJdqfGhiSVO1NEBw\iByLkO2JO69VQ>? NWj3WVJmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyOVI3ODNpPkKzNlUzPjB|PD;hQi=>
CAL27 CisR NVL6S5A5U2mwYYPlJGF{e2G7 MVixPEBp MoLqTY5pcWKrdHnvckBw\iCKRFHDJJdqfGhiSVO1NEBw\iByLk[xJO69VQ>? MmThQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{NUK2NFMoRjJ|MkWyOlA{RC:jPh?=
KYSE-510 CisR MUXLbY5ie2ViQYPzZZk> MXGxPEBp NYPEXlB2UW6qaXLpeIlwdiCxZjDISGFEKHerdHigTWM2OCCxZjCwMlU6KM7:TR?= NX;DNHlkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyOVI3ODNpPkKzNlUzPjB|PD;hQi=>
KYSE-510 sens Mk\MT4lv[XOnIFHzd4F6 M4\EVVE5KGh? MV;Jcohq[mm2aX;uJI9nKEiGQVOge4l1cCCLQ{WwJI9nKDBwNzFOwG0> M1jhVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkWyOlA{Lz5{M{K1NlYxOzxxYU6=
MDA-MB-231 sens NIDxNlJMcW6jc3WgRZN{[Xl? NHTjeFYyQCCq M1fmTWlvcGmkaYTpc44hd2ZiSFTBR{B4cXSqIFnDOVAhd2ZiMD62NUDPxE1? M1TqXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkWyOlA{Lz5{M{K1NlYxOzxxYU6=
MDA-MB-231 CisR NUTiO3N2U2mwYYPlJGF{e2G7 M1;uZ|E5KGh? NHHweXhKdmirYnn0bY9vKG:oIFjERWMhf2m2aDDJR|UxKG:oIECuOlEh|ryP NFXRdmc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{K1NlYxOyd-MkOyOVI3ODN:L3G+
ES2 Mn3uS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUC0PEBp MkjjSG1UVw>? NGLPTlVKSzVyPUGyMlch|ryP MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzR7M{S0PUc,OjN2OUO0OFk9N2F-
MDA-MB-231 NWjMeY5{U2mwYYPlJGF{e2G7 MV6xNEDPxE1? M4K1XlMxKG2rbh?= MWPEUXNQ M3HTTWlvcGmkaYTpc44hd2ZiSFTBR|Ji NHziOHI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{S5N|Q1QSd-MkO0PVM1PDl:L3G+
MDA-MB-231 MmXjT4lv[XOnIFHzd4F6 NE\l[2UyKM7:TR?= NFL3[2UzPCCq M1vXZ2ROW09? NVzQPYpVUW6qaXLpeIlwdiCxZjDISGFEPiCjc4Pld5Nm\CCjczDhZ4V1gWyjdHnvckBt\X[nbIOgc4YhfHWkdXzpci=> M2[yTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NEmzOFQ6Lz5{M{S5N|Q1QTxxYU6=
HS68 NW\H[HNGS3m2b4TvfIlkKEG|c3H5 MkK3NVAh|ryP NITU[3M4OiCq Mk\ESG1UVw>? M2\jOGlEPTB;ND62JO69VQ>? Ml;SQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN3N{C1OFIoRjJ|NUewOVQzRC:jPh?=
MEF NELTfFZEgXSxdH;4bYMhSXO|YYm= Mkm0NVAh|ryP MorCO|IhcA>? M3;0R2ROW09? NVLacmFlUUN3ME20MlQh|ryP NGfCSZk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{W3NFU1Oid-MkO1O|A2PDJ:L3G+
BGC823 NX76d5BPT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{K2NWROW09? MWTHTVUxRTNwMEmg{txO MmTyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4MEG3NFYoRjJ|NkCxO|A3RC:jPh?=
High5 NXzYSmVmU2mwYYPlJGF{e2G7 MkjBNlQhcA>? MYnJcohq[mm2aX;uJI9nKGi3bXHuJJJm[2:vYnnuZY51KEiGQVO2JJdqfGhiSVO1NEBw\iByLkC5JO69VQ>? NGe5RpQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{[wNlUzOyd-MkO2NFI2OjN:L3G+
High5 NICyZopMcW6jc3WgRZN{[Xl? MofUNlQhcA>? NH[2O2RKdmirYnn0bY9vKG:oIHj1cYFvKHKnY3;tZolv[W62IFjERWMyKHerdHigTWM2OCCxZjCwMlEzKM7:TR?= NUDicXBNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO2NFI2OjNpPkKzOlAzPTJ|PD;hQi=>
High5 MWPLbY5ie2ViQYPzZZk> NU\TOIFPOjRiaB?= MWnJcohq[mm2aX;uJI9nKGi3bXHuJJJm[2:vYnnuZY51KEiGQVOzJJdqfGhiSVO1NEBw\iByLkG3JO69VQ>? MkDsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN4MEK1NlMoRjJ|NkCyOVI{RC:jPh?=
A549 NVnzc3hCT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= Ml\lSG1UVw>? MXjJR|UxRTFwMEe5JO69VQ>? MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ2NEKxNEc,OjN4NESyNVA9N2F-
HCT116 MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MXzEUXNQ NWnBbVA{UUN3ME2wMlc2PyEQvF2= MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzZ2NEKxNEc,OjN4NESyNVA9N2F-
K562 MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M3nydWROW09? NX;3PWhwUUN3ME2wMlY1PSEQvF2= M1TUcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|NkS0NlExLz5{M{[0OFIyODxxYU6=
GBC-SD MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MkG3OUDPxE1? NFjwO5Q4OiCq MlPESG1UVw>? M2i2UGlEPTB;MUSuPEDPxE1? MoezQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN5MEeyOlAoRjJ|N{C3NlYxRC:jPh?=
HGC27 M{\4fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NES0VXk2KM7:TR?= NEK2NoU4OiCq Mnf5SG1UVw>? M4O0[mlEPTB;NT60JO69VQ>? M2\CWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|N{C3NlYxLz5{M{ewO|I3ODxxYU6=
HL60 NITMWYlMcW6jc3WgRZN{[Xl? NYDjSnVJPSEQvF2= NYH4[|RMOjRiaB?= NUXlclB5TE2VTx?= MmrkTY5pcWKrdHnvckBw\iCKRFHD M{W1VVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|N{C3NlYxLz5{M{ewO|I3ODxxYU6=
Vero MlTnS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn3XO|IhcA>? MlPjSG1UVw>? MoXqTWM2OD1yLkmg{txO NWTYNJV[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO3PFY1PTJpPkKzO|g3PDV{PD;hQi=>
NCI60 MlvLR5l1d3SxeHnjJGF{e2G7 Ml;2OFghcA>? NWezdZdSTE2VTx?= NHHoSoVIUT1yLkWzJO69VQ>? NFTIXmM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NECxOVMzPyd-MkSwNVU{Ojd:L3G+
SW620 NH7YOIREgXSxdH;4bYMhSXO|YYm= NFO5S|c1QCCq M4jOXWROW09? MVPHTV0xNjV2IN88US=> MmTxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRyMUWzNlcoRjJ2MEG1N|I4RC:jPh?=
U251 M4PsdGN6fG:2b4jpZ{BCe3OjeR?= NHGzU4c1QCCq M2HEdGROW09? MljNS2k:OS53MzFOwG0> NFfYPG49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NECxOVMzPyd-MkSwNVU{Ojd:L3G+
KM12 MXfDfZRwfG:6aXOgRZN{[Xl? M{Pt[|Q5KGh? Mnn5SG1UVw>? M4HwW2dKRTFwOEig{txO NV30SJRuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwNVU{OjdpPkK0NFE2OzJ5PD;hQi=>
Hs578T NFvOcYNEgXSxdH;4bYMhSXO|YYm= MXS0PEBp MlWxSG1UVw>? NIjGd5BIUT12LkizJO69VQ>? NXW1b3JGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSwNVU{OjdpPkK0NFE2OzJ5PD;hQi=>
MDA-MB-231 MkHHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? M1;aU|Q5KGh? Mli3TWM2OD1yLkG2JO69VQ>? M{PyPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2MEm1NFE3Lz5{NEC5OVAyPjxxYU6=
MCF7 M1jEV2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NEC1UVY1QCCq MUTHTV0xNjR3IN88US=> MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDFzOUW1OUc,OjRzMUm1OVU9N2F-
MDA-MB-435 M{W3VWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2jvcFQ5KGh? MljmS2k:OC56ODFOwG0> Ml7RQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjRzMUm1OVUoRjJ2MUG5OVU2RC:jPh?=
AsPC1 M12xdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NI\FTpM{OCEQvF2= M2\EcFQ5KGh? MknqSG1UVw>? NI\FPWhKSzVyPUOuOlYh|ryP MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDF6NUO3PEc,OjRzOEWzO|g9N2F-
Jurkat E6.1 Mnj1T4lv[XOnIFHzd4F6 M{fDZlIhcA>? M13r[mROW09? MV;Jcohq[mm2aX;uJI9nKEiGQVO0JJdqfGhiSVO1NEBw\iByLkC0JO69VQ>? NVHzUYZERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkSyOlE5PjJpPkK0NlYyQDZ{PD;hQi=>
KG1 MWDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NYLkeoZQPDhiaB?= Mlv2TWM2OD1zLkG1JO69VQ>? NV7ONYJCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS1NlUxODNpPkK0OVI2ODB|PD;hQi=>
HEL Ml3CS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHzCVZQ1QCCq MXPEUXNQ NV\GeG5PUUN3ME2wMlQ6KM7:TR?= NFHTWWs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NE[5OFA2PSd-MkS2PVQxPTV:L3G+
HSC3 M3TsU2N6fG:2b4jpZ{BCe3OjeR?= MmP0NVIhcA>? NYD6dYpnTE2VTx?= NG[zU|RKSzVyPUCuO|Eh|ryP MkfCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5Nk[1OlAoRjJ2N{[2OVYxRC:jPh?=
HT-29 M4PYRWN6fG:2b4jpZ{BCe3OjeR?= MoLyNVIhcA>? MmHtSG1UVw>? NFnnWIxKSzVyPUCuO|Ih|ryP MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd4NkW2NEc,OjR5Nk[1OlA9N2F-
KB MXfDfZRwfG:6aXOgRZN{[Xl? NEfFPWgyOiCq MmjnSG1UVw>? NEnWc4dKSzVyPUCuO|Uh|ryP NInae|Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEe2OlU3OCd-MkS3OlY2PjB:L3G+
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MKN45 NUTW[pR3S3m2b4TvfIlkKEG|c3H5 MVixNkBp M{m1TWROW09? NVrNOphbUUN3ME2xMlI2KM7:TR?= M2XIdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{[2OVYxLz5{NEe2OlU3ODxxYU6=
TSGH MoK2R5l1d3SxeHnjJGF{e2G7 MnnjNVIhcA>? NXz6TmltTE2VTx?= M1\qT2lEPTB;Mj6wPUDPxE1? NWjueFJuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3OlY2PjBpPkK0O|Y3PTZyPD;hQi=>
HL60 NFrORWRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXmzd5JzPzJiaB?= M4XEeGROW09? MUnHTVUxRTBwOUOg{txO MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDlyMEWwNEc,OjR7MEC1NFA9N2F-
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