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All New Products Listed Chronologically

製品コード 製品名称 製品説明 添加時期
A2186 Anti-mouse CD276 (B7-H3) [MJ18] Anti-mouse CD276 (B7-H3) [MJ18] reacts with mouse CD276 also known as B7-H3. CD276 is a type I transmembrane protein and a member of the B7 family of co-stimulatory proteins. Sep 02 2026
A2187 Anti-mouse CD73 [TY/23] Anti-mouse CD73 [TY/23] reacts with mouse CD73 also known as ecto-5′-nucleotidase (5′-NT), a 69 kDa GPI-anchored cell-surface protein. In mice, expression of CD73 is restricted to CD11b+ myeloid cells in the bone marrow and T cells in the spleen. Sep 02 2026
A2188 Anti-mouse IL-9 [9C1] Anti-mouse IL-9 [9C1] reacts with mouse IL-9, a pleiotropic cytokine expressed by Th9 cells, Th2 cells, Th17 cells, regulatory T cells, NKT cells, ILC2s, and mast cells. Sep 02 2026
E6952 Dimethyl 2-oxoglutarate Aug 31 2026
E6948 TGFβ1-IN-1 Aug 31 2026
E0869 hSMG-1 inhibitor 11j Aug 31 2026
E6662 BDTX‑4933 Aug 31 2026
E6441 clifutinib Aug 31 2026
E6875 SU0617 Aug 31 2026
E6863 Prifemilast Aug 31 2026
A2184 Anti-mouse CD54 (ICAM-1)-Invivo [YN1/1.7.4] Anti-mouse CD54 (ICAM-1)-Invivo [YN1/1.7.4] reacts with mouse CD54 also known as Intercellular Adhesion Molecule-1 (ICAM-1). CD54 is a 90 kDa single-chain transmembrane glycoprotein and a member of the Ig superfamily. Aug 26 2026
A2185 Anti-human/monkey CD28-Invivo [CD28.2] Anti-human/monkey CD28-Invivo [CD28.2] reacts with human and monkey CD28, a 45 kDa costimulatory receptor and a member of the Ig superfamily. CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. Aug 26 2026
P1237 Survodutide Survodutide (BI 456906) is a potent, selective GCGR/GLP‑1R dual agonist with an EC50 of 0.52 nM and 0.33 nM in CHO‑K1 cells, respectively. It exerts robust anti‑obesity efficacy by increasing energy expenditure and decreasing food intake. Aug 26 2026
E6814 APL-4098 APL-4098 is an orally active, selective, ATP‑competitive GCN2 (EIF2AK4) inhibitor with Ki of 4.39 nM and Kd of 2.9 nM. APL‑4098 impairs mitochondrial function and triggers the mitochondrial unfolded protein response, leading to cytotoxicity in primary AML cells, including leukemia stem cells. Aug 25 2026
E5929 Oteseconazole Oteseconazole(VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity with a of Kd ≤39 nM, shows no obvious effect on human CYP51. Aug 25 2026
E6903 p-Aminophenylmercuric acetate p‑Aminophenylmercuric acetate (APMA) is an organomercurial activator of matrix metalloproteinases (MMPs) that acts via the cysteine‑switch to activate latent MMPs (including MMP‑8), promotes pro‑betacellulin shedding, and modulates opiate receptor ligand binding. Aug 24 2026
E6797 MTK458 MTK458(EP-0035985) is a synthetic, orally bioavailable, brain‑penetrant small‑molecule activator of PINK1 (PTEN‑induced kinase 1). It binds directly to PINK1 and stabilizes an active PINK1 heterocomplex (with TOM machinery), which increases PINK1 kinase activity and drives downstream mitophagy. Aug 23 2026
E6837 KT-621 KT‑621 is a selective, once‑daily oral degrader of STAT6, the essential transcription factor in the IL‑4/IL‑13 pathway, with high clinical potential for Type 2 inflammatory diseases such as atopic dermatitis and asthma/COPD. Aug 23 2026
E6848 KDS-12025 KDS12025 is a BBB‑permeable small molecule that enhances hemoglobin (Hb) pseudoperoxidase activity ~100‑fold with an EC50 of 0.04 µM, enabling effective H₂O₂ decomposition even at extremely low Hb levels. Aug 23 2026
A2181 Anti-mouse GITR-Invivo [DTA-1] Anti-Mouse GITR-Invivo [DTA-1] reacts with mouse GITR (glucocorticoid-induced TNFR-related gene), a 66-70 kDa co-stimulatory immune checkpoint molecule belonging to the Tumor Necrosis Factor superfamily (TNFRSF18). Anti-Mouse GITR-Invivo [DTA-1] is an agonistic antibody that is commonly used to induce GITR signaling in vivo. Aug 21 2026
A2182 Anti-mouse/human CD11b-Invivo [M1/70] Anti-mouse/human CD11b-Invivo [M1/70] reacts with mouse and human CD11b, a 170 kDa membrane glycoprotein also known as integrin alpha M (ITGAM). CD11b belongs to the integrin alpha family and is primarily expressed on granulocytes and monocytes/macrophages but also expressed on dendritic cells, NK cells, and subsets of T and B cells. Aug 21 2026
A2183 Anti-mouse IL-7Rα (CD127)-Invivo [A7R34] Anti-mouse IL-7Rα (CD127)-Invivo [A7R34] reacts with mouse IL-7Rα also known as CD127. IL-7Rα is a 60-90 kDa type I transmembrane glycoprotein expressed on immature B cells, thymocytes, peripheral T cells, and bone marrow stromal cells. Aug 21 2026
E1285 Cedazuridine Cedazuridine (E7727; Compound 7a) is an orally active, synthetic nucleoside analog derived from tetrahydrouridine that functions as a potent cytidine deaminase (CDA) inhibitor with an IC50 of 0.4 μM. Aug 19 2026
E6592 N1-Methylpseudouridine N1-Methylpseudouridine(N1-methyl-pseudouridine) is a modified uridine nucleoside used in RNA research and mRNA-based technologies. It enhances mRNA translation relative to unmodified or alternative modified nucleosides by reducing PKR-associated translational repression and by increasing ribosome density through effects on translation initiation and elongation. Aug 19 2026
E5944 AMPK-IN-3 AMPK‑IN‑3 (compound 67) is a potent, oxindole‑based, ATP‑site inhibitor of AMP‑activated protein kinase (AMPK), with IC50 of 60.7 nM for AMPKα2, 107 nM for AMPKα1, and 3,820 nM for KDR (VEGFR2). It also effectively suppresses cellular AMPK activity without significantly affecting cell viability or inducing cytotoxicity in chronic myeloid leukemia K562 cells. Aug 16 2026
E6915 Tienilic acid Tienilic acid (ticrynafen; ANP-3624) is a withdrawn uricosuric diuretic and antihypertensive drug that undergoes CYP2C9-mediated bioactivation to reactive electrophilic metabolites. These metabolites covalently modify hepatic proteins and contribute to its characteristic idiosyncratic and immunoallergic hepatotoxicity. Aug 16 2026
E6887 MBoIN179 MBoIN179 is a small-molecule modulator that disrupts the transmembrane-domain interaction between the anti-apoptotic protein MCL1 and the pro-apoptotic protein BOK. By releasing BOK from MCL1-mediated sequestration, MBoIN179 promotes BOK-dependent oligomerization and mitochondrial outer-membrane permeabilization, thereby inducing apoptotic cell death. Aug 16 2026
E6898 GSK-A1 GSK‑A1 is a selective, ATP‑competitive inhibitor of type III phosphatidylinositol 4‑kinase α (PI4KA/PI4KIIIα), with pIC50 of 8.5–9.8 and high selectivity over PI4KIIIβ and most class I PI3Ks. It potently blocks PI4P production at the plasma membrane, thereby inhibiting PtdIns(4,5)P₂ resynthesis during strong PLC activation (IC50 ≈ 3 nM), while acutely decreasing PtdIns(4)P with only a negligible direct effect on steady‑state PtdIns(4,5)P₂ levels. Aug 16 2026
F4001 Vasopressin Antibody (Rabbit mAb) [P14E10] Aug 14 2026
F0249 Phospho-MAPKAPK-2 (Thr334) Antibody (Rabbit mAb) [J17A19] Aug 14 2026
F4395 IFN-α/β Receptor Chain 2 Antibody (Mouse mAb) [A11L23] Aug 14 2026
F1534 DNA/RNA Damage Antibody (Mouse mAb) [D16E12] Aug 14 2026
F4596 NGF Antibody (Rabbit mAb) [F20J13] Aug 14 2026
F4758 TET2 Antibody (Rabbit mAb) [B6D15] Aug 14 2026
F4900 Hantavirus nucleocapsid protein Antibody (Mouse mAb) [A11N7] Aug 14 2026
F3963 GABARAP Antibody (Rabbit mAb) [P12P16] Aug 14 2026
F5139 Phospho-β-Catenin (Ser33) Antibody (Rabbit mAb) [M22A24] Aug 14 2026
F2239 Pericentrin Antibody (Rabbit mAb) [N1M2] Aug 14 2026
F4576 CCL5/RANTES Antibody (Mouse mAb) [K11A8] Aug 14 2026
F5951 TWIST1 Antibody (Rabbit mAb) [M21K22] Aug 14 2026
F3674 Snail + Slug N-terminal Antibody (Mouse mAb) [E10J13] Aug 14 2026
F8436 BRCA1 Antibody (Mouse mAb) [K2A11] Aug 14 2026
F1146 β Amyloid (Aβ) 1-42 Antibody (Rabbit mAb) [M4F1] Aug 14 2026
F9487 Phospho-Mnk1 (Thr197/202) Antibody (Rabbit mAb) [A20A1] Aug 14 2026
F1044 NFAT2 Antibody (Mouse mAb) [P20K6] Aug 14 2026
F5591 ALP Antibody (Rabbit mAb) [B19A18] Aug 14 2026
F7043 IL-1RL1/ST2 Antibody (Mouse mAb) [M15P5] Aug 14 2026
F9987 CXCL10/IP-10 Antibody (Rabbit mAb) [A14K20] Aug 14 2026
F7124 Reelin Antibody (Rabbit mAb) [M2J11] Aug 14 2026
F8242 BRD7 Antibody (Rabbit mAb) [N9J16] Aug 14 2026
F2136 Perlecan/HSPG2 Antibody (Rat mAb) [E7K4] Aug 14 2026
F8739 Osteopontin Antibody (Rabbit mAb) [G3A21] Aug 14 2026
F4817 Hsp40 Antibody (Rabbit mAb) [A24K14] Aug 14 2026
F3833 Laminin Antibody (Mouse mAb) [E12M18] Aug 14 2026
F7578 TGF β1 Antibody (Rabbit mAb) [N23L9] Aug 14 2026
F8328 Orexin A Antibody (Rabbit mAb) [P6H3] Aug 14 2026
F2130 CD59 Antibody (Mouse mAb) [M4G24] Aug 14 2026
F4947 α-Skeletal Muscle Actin Antibody (Rabbit mAb) [P10M5] Aug 14 2026
F9472 CXCL13 Antibody (Rabbit mAb) [E12F15] Aug 14 2026
F5835 C-Peptide Antibody (Rabbit mAb) [H2G21] Aug 14 2026
F8584 CCL20/MIP-3α Antibody (Rabbit mAb) [G18F18] Aug 14 2026
F6555 HNF1α Antibody (Rabbit mAb) [E10H19] Aug 14 2026
F7372 GPNMB Antibody (Rabbit mAb) [H14J12] Aug 14 2026
F5507 TARC/CCL17 Antibody (Rabbit mAb) [P14H22] Aug 14 2026
F5975 p38γ/MAPK12 Antibody (Rabbit mAb) [F12K4] Aug 14 2026
F5568 ADX Antibody (Rabbit mAb) [H7P21] Aug 14 2026
F6675 STIM2 C-terminal Antibody (Rabbit mAb) [N9G10] Aug 14 2026
F5719 Phospho-AMPKα2 (Ser491) Antibody (Rabbit mAb) [J2M12] Aug 14 2026
F5510 α-Skeletal Muscle Actin Antibody (Rabbit mAb) [A24H10] Aug 14 2026
F3815 Caveolin 3 Antibody (Mouse mAb) [L5G2] Aug 14 2026
F2781 S100P Antibody (Rabbit mAb) [D16M19] Aug 14 2026
F5624 TSG101 Antibody (Rabbit mAb) [K21M20] Aug 14 2026
F5662 TRAF3 Antibody (Rabbit mAb) [E9G8] Aug 14 2026
F3173 Carboxymethyl Lysine Antibody (Mouse mAb) [B15G14] Aug 14 2026
F2785 Caspase6 Antibody (Rabbit mAb) [L13G8] Aug 14 2026
F9389 Coagulation Factor III/Tissue Factor Antibody (Rabbit mAb) [C11F17] Aug 14 2026
F5579 CD3 ζ Antibody (Armenian hamster mAb) [N1P1] Aug 14 2026
F0337 PTEN Antibody (Rabbit mAb) [E1G6] Aug 14 2026
F2369 STAT5a Antibody (Rabbit mAb) [J3A20] Aug 14 2026
F2697 CD62E/E-Selectin Antibody (Mouse mAb) [A9C19] Aug 14 2026
F9796 Rab11A Antibody (Rabbit mAb) [N14G1] Aug 14 2026
F8916 GCLC Antibody (Rabbit mAb) [D14E17] Aug 14 2026
F7923 Galectin-9 Antibody (Rabbit mAb) [K4C23] Aug 14 2026
F6353 WDR77 Antibody (Rabbit mAb) [K8F2] Aug 14 2026
F5765 GRK3 Antibody (Rabbit mAb) [F23P23] Aug 14 2026
F8976 Ubc12 Antibody (Rabbit mAb) [B20L23] Aug 14 2026
F7438 GLO1 Antibody (Rabbit mAb) [D11D19] Aug 14 2026
F7770 Erk5 Antibody (Rabbit mAb) [P11L5] Aug 14 2026
F5571 HIF1AN/FIH-1 Antibody (Rabbit mAb) [G7L22] Aug 14 2026
F5290 YTHDF3 Antibody (Rabbit mAb) [P16G5] Aug 14 2026
F8334 L1CAM Antibody (Rabbit mAb) [M4J1] Aug 14 2026
F9896 MUC2 Antibody (Rabbit mAb) [M5E4] Aug 14 2026
F7782 Galectin 8/Gal-8 Antibody (Rabbit mAb) [J21J20] Aug 14 2026
F5527 CUL3 Antibody (Rabbit mAb) [N12N7] Aug 14 2026
F7404 STRAP Antibody (Mouse mAb) [E8J9] Aug 14 2026
F6632 Kindlin-3 Antibody (Rabbit mAb) [B13M6] Aug 14 2026
F5928 Phospho-Numb (Ser276) Antibody (Rabbit mAb) [G21B13] Aug 14 2026
F6983 KPNB1 Antibody (Rabbit mAb) [M6A17] Aug 14 2026
F9578 CXCL13 Antibody (Rabbit mAb) [N2C21] Aug 14 2026
F4086 p53 Antibody (Mouse mAb) [G3A5] Aug 14 2026
F5958 Otoferlin Antibody (Rabbit mAb) [P6C24] Aug 14 2026
F5371 REEP5 Antibody (Mouse mAb) [E6M2] Aug 14 2026
F5620 SNX27 Antibody (Rabbit mAb) [P13M24] Aug 14 2026
F6304 SREBP1 Antibody (Rabbit mAb) [J4J22] Aug 14 2026
F8042 PACT (PKR activating protein) / PRKRA Antibody (Rabbit mAb) [E15C21] Aug 14 2026
F6153 HJURP Antibody (Rabbit mAb) [H17B23] Aug 14 2026
F6622 ZO-3 Antibody (Rabbit mAb) [C8F20] Aug 14 2026
F6750 KDEL Antibody (Rabbit mAb) [C2B2] Aug 14 2026
F5475 hnRNP M1-M4 Antibody (Rabbit mAb) [J19E5] Aug 14 2026
F5284 CD10/Neprilysin Antibody (Rabbit mAb) [J20L24] Aug 14 2026
F6328 PKCγ Antibody (Rabbit mAb) [F18C13] Aug 14 2026
F7416 COX5A Antibody (Rabbit mAb) [H4E6] Aug 14 2026
F5379 LXRβ/NER Antibody (Rabbit mAb) [L4N23] Aug 14 2026
F8329 XRN2 Antibody (Rabbit mAb) [J9K11] Aug 14 2026
F5865 Phospho-Tyrosine Hydroxylase (Ser31) Antibody (Rabbit mAb) [G15H6] Aug 14 2026
F7790 CLIC4 Antibody (Rabbit mAb) [N10P8] Aug 14 2026
F7341 TPN Antibody (Rabbit mAb) [N20A4] Aug 14 2026
F8632 Phospho-PLCG 2 (Tyr759) Antibody (Rabbit mAb) [N11A6] Aug 14 2026
F6470 Mesothelin Antibody (Rabbit mAb) [G1K4] Aug 14 2026
F9913 BAFF Antibody (Rabbit mAb) [J1C19] Aug 14 2026
F5989 Matrin 3 Antibody (Rabbit mAb) [D18G16] Aug 14 2026
F6255 Aquaporin 1 Antibody (Rabbit mAb) [H8N3] Aug 14 2026
F6880 Fez1 Antibody (Rabbit mAb) [F20M11] Aug 14 2026
F5514 CD54/ICAM-1 Antibody (Rabbit mAb) [M4J17] Aug 14 2026
F6546 JNK1 + JNK2 + JNK3 Antibody (Rabbit mAb) [G2M15] Aug 14 2026
F6968 VPRBP Antibody (Rabbit mAb) [D9F7] Aug 14 2026
F6838 CD20 Antibody (Rabbit mAb) [M12N6] Aug 14 2026
F7452 Collagen IV Antibody (Rabbit mAb) [L21P9] Aug 14 2026
F7031 Podoplanin Antibody (Rabbit mAb) [K11E7] Aug 14 2026
F8876 HEC1/HEC Antibody (Rabbit mAb) [H9F1] Aug 14 2026
F0783 HDAC2 Antibody (Rabbit mAb) [C7F21] Aug 14 2026
F7254 Scavenging Receptor SR-BI Antibody (Rabbit mAb) [B5C22] Aug 14 2026
F8043 RPA32/RPA2 Antibody (Rabbit mAb) [P9J16] Aug 14 2026
F5702 KIF5B Antibody (Rabbit mAb) [F6C8] Aug 14 2026
F5600 WASP Antibody (Rabbit mAb) [E16K19] Aug 14 2026
F8402 ENO1 Antibody (Rabbit mAb) [G5C3] Aug 14 2026
F8950 PKD2 Antibody (Rabbit mAb) [D13D19] Aug 14 2026
F9334 ERG Antibody (Rabbit mAb) [P8K24] Aug 14 2026
F8297 HOXA10 Antibody (Rabbit mAb) [M2L19] Aug 14 2026
F5469 pro Caspase3 Antibody (Rabbit mAb) [D14C8] Aug 14 2026
F5824 Mast Cell Tryptase Antibody (Rabbit mAb) [M18M6] Aug 14 2026
F5918 FAAH1 Antibody (Rabbit mAb) [H15C21] Aug 14 2026
F4408 Puromycin Antibody (Mouse mAb) [M15P20] Aug 14 2026
F7725 Protein A Antibody (Mouse mAb) [E20E21] Aug 14 2026
F9204 Prealbumin Antibody (Rabbit mAb) [F23G8] Aug 14 2026
F8528 MTHFR Antibody (Rabbit mAb) [N5P2] Aug 14 2026
F5212 ARF4 Antibody (Mouse mAb) [M2B13] Aug 14 2026
F7594 DHODH Antibody (Rabbit mAb) [N8E14] Aug 14 2026
F7307 Musashi 1 / Msi1 Antibody (Rabbit mAb) [J9N24] Aug 14 2026
F8015 SOAT1/ACAT1 Antibody (Rabbit mAb) [L22J7] Aug 14 2026
F5550 PHD1 Antibody (Rabbit mAb) [F19A8] Aug 14 2026
F2919 Calprotectin (S100A8+A9 complex) Antibody (Mouse mAb) [H13D24] Aug 14 2026
F5277 EGR2 Antibody (Rabbit mAb) [E12D8] Aug 14 2026
F7018 FACL4 Antibody (Rabbit mAb) [C8B1] Aug 14 2026
F6735 BACH2 Antibody (Rabbit mAb) [N18E12] Aug 14 2026
F3800 VAP1 Antibody (Rat mAb) [G15D13] Aug 14 2026
E6554 PF-07293893 PF-07293893 is an oral, selective small-molecule activator of the AMPKγ3 (PRKAG3) regulatory subunit and exhibits potential to treat heart failure with preserved ejection fraction (HFpEF). Aug 13 2026
E6881 TSQ TSQ is a membrane‑permeant, quinoline‑based fluorescent probe widely used to image labile zinc pools and zinc‑bound proteins in live cells. TSQ predominantly forms ternary TSQ–Zn–protein adducts that emit with a blue‑shifted maximum near 470 nM, whereas the simple 2:1 Zn(TSQ)₂ complex in solution peaks closer to 490–495 nM. Aug 13 2026
E6923 Tudociclib(INCB123667) Tudociclib(INCB123667) is a potent and selective oral small‑molecule inhibitor of CDK2 that suppresses tumor growth and exhibits acceptable safety and preliminary efficacy in patients with advanced solid tumors. Aug 13 2026
E6783 BMS-986482 BMS-986482 is a next-generation, cereblon (CRBN)-dependent molecular glue degrader that drives pan-IKZF degradation (IKZF1–4) via a non-traditional CELMoD core. It also exhibits potential to be used in advanced solid tumors. Aug 12 2026
E6810 TNG-6266 TNG‑6266 is an early‑stage chemical probe in the HBS1L‑targeting molecular glue degrader series, with a cellular HBS1L DC50 >10 μM. Aug 12 2026
E6884 KyA33 KyA33 is a selective, non‑covalent small‑molecule inhibitor of ALDH1A2 with dual activity against ALDH1A2/ALDH1A3 that blocks local retinoic acid (RA) biosynthesis. By suppressing autocrine RA signaling in dendritic cells (DCs) and tumor cells, KyA33 enhances DC function and antitumor immunity. Aug 10 2026
E6455 MitoTracker Green FM MitoTracker Green FM is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. It covalently binds mitochondrial proteins by reacting with free mercaptan (thiol) groups on cysteine residues, enabling mitochondrial staining independent of membrane potential. Aug 06 2026
E6900 TPC2-A1-N TPC2-A1-N is a potent, cell-permeable, Ca²⁺-permeable agonist of two-pore channel 2 (TPC2) that evokes substantial TPC2-dependent Ca²⁺ responses in intact cells, with an EC50 of 7.8 μM in a cell-based Ca²⁺-imaging assay. Aug 06 2026
E6021 Aceclidine Aceclidine(Quinuclidin-3-yl acetate) is a quinuclidine-based cholinergic agonist that acts on muscarinic acetylcholine receptors M1-M5, stimulating phosphoinositide hydrolysis at M1, M3, and M5 and inhibiting cyclic AMP accumulation at M2 and M4. It also acts as a pupil-selective miotic, contracting the iris sphincter to produce a pinhole pupil that extends depth of focus and improves near vision with minimal ciliary muscle stimulation. Aceclidine (Quinuclidin-3-yl acetate) is a modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC50: 40 μM). Aug 02 2026
E1828 BHV-8000 BHV-8000 (TLL-041) is a first-in-class, oral, brain-penetrant, dual TYK2/JAK1 selective inhibitor that targets the JAK-STAT pathway signaling implicated in the mixed inflammatory response driving progression of many neuroinflammatory and neurodegenerative conditions, including Parkinson's disease, Alzheimer's disease, and multiple sclerosis. Jul 29 2026
E6598 CY3 Cy3 (Sulfo-Cyanine3) is a bright orange-red fluorescent cyanine dye used for labeling proteins and nucleic acids, with excitation/emission maxima of approximately 554 nm/568 nm. It is the sulfonated, water-soluble analog of classic Cy3, with improved aqueous solubility and suitability for labeling biomolecules under mild, aqueous conditions. Jul 29 2026
P1278 Brenipatide Brenipatide (LY-3537031) is a dual GLP-1/GIP receptor agonist with the potential to be used in addiction and psychiatric indications, alongside standard metabolic/obesity studies. Jul 27 2026
E6896 ITK inhibitor 2 ITK inhibitor 2 (compound 4) is an inhibitor of ITK with an IC50 of 2 nM, with potential to be used in research on inflammatory diseases, allergic diseases, autoimmune diseases, and transplant rejection. Jul 27 2026
E6821 Zinpyr-1 Zinpyr-1 is a membrane-permeable fluorescent zinc probe that can be used to quantify free serum Zn2+ and to visualize relative zinc distribution in plant root cells, supporting analyses of zinc transporter mutants and zinc homeostasis. Jul 22 2026
E6717 Monepantel Monepantel (AAD1566, NUZ-001) is an antiparasitic agent and orally active mTOR inhibitor that promotes autophagy via the mTOR/p70S6K pathway. It modulates nematode-specific nAChR subunits in nematodes and exhibits the potential to be studied in ALS and ovarian cancer. Jul 22 2026
E6815 Ocadusertib Ocadusertib (LY3871801; R-552) is a potent, selective allosteric RIPK1 inhibitor that blocks RIPK1 enzymatic activity with an IC50 of 12–38 nM and inhibits necroptosis in cell-based assays. Jul 22 2026
P1274 Ribupatide HRS9531 (ribupatide) is an oral dual GLP‑1/GIP receptor agonist that demonstrates potent glycemic control and clinically meaningful weight‑loss efficacy in obesity and type 2 diabetes trials. Jul 15 2026
E1291 SETDB1-TTD-IN-1 SETDB1‑TTD‑IN‑1 is a SETDB1 methyltransferase activator and a competitive inhibitor of the SETDB1 tandem tudor domain (SETDB1‑TTD), binding SETDB1‑TTD with a Kd of 88 nM and showing strong selectivity over other tudor and bromodomain proteins. It enhances SETDB1 catalytic activity, promoting Akt1 Lys64 methylation and subsequent Akt1 Thr308 phosphorylation and activation. By blocking SETDB1‑TTD binding to histone H3 peptides, it drives global gene‑expression changes and functions as a tool compound to study SETDB1‑TTD, including in breast cancer models. Jul 15 2026
F2198 Cytokeratin 3 Antibody (Mouse mAb) [N24P21] Jul 13 2026
F2719 SARS-CoV/SARS-CoV-2 (COVID-19) spike Antibody (Mouse mAb) [D3A15] Jul 13 2026
F3942 SNTB2 Antibody (Mouse mAb) [A10J19] Jul 13 2026
F0029 HuC + HuD Antibody (Mouse mAb) [M16B6] Jul 13 2026
F0836 Cleaved IL-1β (Asp117) Antibody (Rabbit mAb) [F15J4] Jul 13 2026
F7747 Ctip1/BCL-11A Antibody (Mouse mAb) [A3G8] Jul 13 2026
F0522 Phospho-JAK2 (Tyr1007+1008) Antibody (Rabbit mAb) [A2P24] Jul 13 2026
F7534 Phospho-DDR1/DDR2 (Tyr796/740) Antibody (Mouse mAb) [M16G11] Jul 13 2026
F5840 DLL4 Antibody (Hamster mAb) [N12K10] Jul 13 2026
F1503 Phospho-ALK (Tyr1278) Antibody (Rabbit mAb) [N16F10] Jul 13 2026
F0926 O-linked N-acetylglucosamine/O-GlcNAc Antibody (Mouse mAb) [B1J22] Jul 13 2026
F3486 GLI-2 Antibody (Mouse mAb) [H16L16] Jul 13 2026
F3601 CYP7B1 Antibody (Rabbit mAb) [M6P12] Jul 13 2026
F9693 CTLA-4 Antibody (Rabbit mAb) [N24K13] Jul 13 2026
F7040 CXCL11/I-TAC Antibody (Mouse mAb) [F19K22] Jul 13 2026
F6204 Leptin Antibody (Mouse mAb) [D16P10] Jul 13 2026
F3806 Connexin 45 Antibody (Mouse mAb) [N18M22] Jul 13 2026
F5352 Pancreatic Polypeptide Antibody (Rabbit mAb) [L20N2] Jul 13 2026
F5341 MDC1 Antibody (Rabbit mAb) [B5B12] Jul 13 2026
F7444 TOM70 Antibody (Rabbit mAb) [N12A7] Jul 13 2026
F6821 INCENP Antibody (Mouse mAb) [L10F19] Jul 13 2026
F6741 Orexin Antibody (Rabbit mAb) [F2B23] Jul 13 2026
F8035 BHMT Antibody (Mouse mAb) [M13A7] Jul 13 2026
F4858 Integrin β4 Antibody (Rabbit mAb) [A13J24] Jul 13 2026
F0796 Phospho-Bim (Ser69) Antibody (Rabbit mAb) [C24C5] Jul 13 2026
F8714 FLG/Filaggrin Antibody (Mouse mAb) [A20F21] Jul 13 2026
F9788 IL-18 Rα/IL-1 R5 Antibody (Mouse mAb) [F14H3] Jul 13 2026
F4508 plexin-B1 Antibody (Mouse mAb) [H18F16] Jul 13 2026
F4419 GPR120 Antibody (Mouse mAb) [C23A11] Jul 13 2026
F2988 SLC22A3/OCT3 Antibody (Rabbit mAb) [J20M4] Jul 13 2026
F6941 GBP5 Antibody (Rabbit mAb) [E17P6] Jul 13 2026
F6788 Glutamate Dehydrogenase 1/2 Antibody (Rabbit mAb) [D16D18] Jul 13 2026
F5852 EBV Nuclear Antigen/EBNA1 Antibody (Rabbit mAb) [L8D4] Jul 13 2026
F3429 MYH6+Slow Skeletal Myosin Heavy chain Antibody (Rabbit mAb) [E13G18] Jul 13 2026
F4281 Ob-R/Leptin Receptor Antibody (Mouse mAb) [F2B5] Jul 13 2026
F5844 HIP1 Antibody (Rabbit mAb) [B10P18] Jul 13 2026
F8972 Hck Antibody (Rabbit mAb) [J18G8] Jul 13 2026
F8723 MAPRE1/EB1 Antibody (Rat mAb) [A10K23] Jul 13 2026
F4889 CDX2 Antibody (Rabbit mAb) [B7K17] Jul 13 2026
F3307 Gankyrin Antibody (Rabbit mAb) [K15B19] Jul 13 2026
F5465 FYCO1 Antibody (Rabbit mAb) [G4K12] Jul 13 2026
F5305 Rhodopsin Antibody (Rabbit mAb) [M1K19] Jul 13 2026
F7554 LARP1 Antibody (Mouse mAb) [A14G14] Jul 13 2026
F8312 Aconitase 1/ACO1 Antibody (Rabbit mAb) [K17A22] Jul 13 2026
F7345 Aromatase Antibody (Rabbit mAb) [D20L3] Jul 13 2026
F7431 B7H4 Antibody (Rabbit mAb) [B6K4] Jul 13 2026
F5802 HEPACAM Antibody (Rabbit mAb) [E11A10] Jul 13 2026
F6614 Phospho-Smad2/Smad3 (Thr8) Antibody (Rabbit mAb) [A2E13] Jul 13 2026
F7201 EEF2K Antibody (Rabbit mAb) [C1A24] Jul 13 2026
F5845 CDCP1 Antibody (Rabbit mAb) [M22E10] Jul 13 2026
F8203 Decorin Antibody (Rabbit mAb) [E13A13] Jul 13 2026
F6115 IL-1α Antibody (Rabbit mAb) [A23L5] Jul 13 2026
F6770 Integrin α2 Antibody (Rabbit mAb) [D4G23] Jul 13 2026
F7639 CD54/ICAM-1 Antibody (Rabbit mAb) [L16P13] Jul 13 2026
F9062 hnRNP D/AUF1 Antibody (Rabbit mAb) [N3C13] Jul 13 2026
F6422 TM9SF2 Antibody (Rabbit mAb) [L17H20] Jul 13 2026
F6260 AIM2 Antibody (Mouse mAb) [C10K13] Jul 13 2026
F9664 YTHDC1 Antibody (Rabbit mAb) [A18C13] Jul 13 2026
F9390 SGK1 Antibody (Rabbit mAb) [A6H22] Jul 13 2026
F3852 p50 dynamitin Antibody (Rabbit mAb) [D19H9] Jul 13 2026
F4199 Toll-like Receptor 4 Antibody (Rabbit mAb) [D2G12] Jul 13 2026
F6754 Dcp1a Antibody (Rabbit mAb) [C9H17] Jul 13 2026
F7213 Von Willebrand Factor Antibody (Rabbit mAb) [L10F8] Jul 13 2026
F6417 CD177 Antibody (Rabbit mAb) [L24N17] Jul 13 2026
F0737 MOB1 Antibody (Rabbit mAb) [P2B21] Jul 13 2026
F7972 SLP-76 Antibody (Rabbit mAb) [B17D20] Jul 13 2026
F8601 Phospho-RPA32/RPA2 (Ser8) Antibody (Rabbit mAb) [B9B12] Jul 13 2026
F9861 Filamin B Antibody (Rabbit mAb) [L9N6] Jul 13 2026
F6261 PTBP2 Antibody (Rabbit mAb) [P6J9] Jul 13 2026
F6584 KAT8/MYST1/MOF Antibody (Rabbit mAb) [L19F21] Jul 13 2026
F7579 CBX4 Antibody (Rabbit mAb) [P20K12] Jul 13 2026
F1494 Phospho-ALK (Tyr1282/1283) Antibody (Rabbit mAb) [K9K20] Jul 13 2026
F8671 Stargazin Antibody (Rabbit mAb) [D18F22] Jul 13 2026
F1089 Histone H3 (di methyl Lys4) Antibody (Rabbit mAb) [G7H21] Jul 13 2026
F7105 Phospho-BCKDHA (Ser293) Antibody (Rabbit mAb) [D4N17] Jul 13 2026
F6065 LYRIC/AEG1 Antibody (Rabbit mAb) [E12A5] Jul 13 2026
F7535 CEBP δ/CEBPD Antibody (Rabbit mAb) [F16N9] Jul 13 2026
F7159 ADX Antibody (Rabbit mAb) [F18K2] Jul 13 2026
F5981 Phospho-Vimentin (Ser56) Antibody (Rabbit mAb) [J12E11] Jul 13 2026
F5877 MNDA Antibody (Rabbit mAb) [B9K11] Jul 13 2026
F8298 Dnmt3L Antibody (Rabbit mAb) [N11C3] Jul 13 2026
F2152 BRAF (mutated V600E) Antibody (Mouse mAb) [M8P1] Jul 13 2026
F8699 CCL3/MIP-1α Antibody (Rabbit mAb) [C14N6] Jul 13 2026
F5801 Septin 2 Antibody (Rabbit mAb) [D4N13] Jul 13 2026
F9144 Carbonic Anhydrase 3/CA3 Antibody (Rabbit mAb) [N13C2] Jul 13 2026
F7063 Coronin 1a/TACO Antibody (Rabbit mAb) [N18B9] Jul 13 2026
F9659 CAND1 Antibody (Rabbit mAb) [B17D18] Jul 13 2026
F5207 Casein Kinase 1α Antibody (Rabbit mAb) [B16K10] Jul 13 2026
F3076 MMP-7 Antibody (Rabbit mAb) [G24L14] Jul 13 2026
F5655 SF3B3 Antibody (Rabbit mAb) [J19B20] Jul 13 2026
F6726 CIRP Antibody (Rabbit mAb) [P15P18] Jul 13 2026
F8260 Phospho-SIRT1 (Ser47) Antibody (Rabbit mAb) [P1D17] Jul 13 2026
F6697 Visfatin Antibody (Rabbit mAb) [F13J14] Jul 13 2026
F7231 Cyclophilin B Antibody (Rabbit mAb) [F10F4] Jul 13 2026
F6797 CIRP Antibody (Rabbit mAb) [N23M15] Jul 13 2026
F8478 PUS7 Antibody (Rabbit mAb) [D18B10] Jul 13 2026
F5193 RAGE Antibody (Rabbit mAb) [E24P22] Jul 13 2026
F0443 Pan-Keratin Antibody (Mouse mAb) [F22F9] Jul 13 2026
F6605 PSME1 Antibody (Rabbit mAb) [G15C24] Jul 13 2026
F9562 KAT9/Elp3 Antibody (Rabbit mAb) [D16L5] Jul 13 2026
F7950 ROR2 Antibody (Rabbit mAb) [A21B16] Jul 13 2026
F7058 PSMB6 Antibody (Rabbit mAb) [G20N21] Jul 13 2026
F7964 Acetyl-Histone H3 (Lys23) Antibody (Rabbit mAb) [E10E19] Jul 13 2026
F5164 CAMKIV Antibody (Rabbit mAb) [P4P15] Jul 13 2026
F5658 PHGDH Antibody (Mouse mAb) [H19P14] Jul 13 2026
F9223 AIP Antibody (Rabbit mAb) [J10D14] Jul 13 2026
F7902 CXCR4 Antibody (Rabbit mAb) [N1P5] Jul 13 2026
F5578 COUP-TFII Antibody (Rabbit mAb) [E21A14] Jul 13 2026
F8053 Cytokeratin 19 Antibody (Rabbit mAb) [B7G11] Jul 13 2026
F2666 TIGIT Antibody (Rabbit mAb) [J11M4] Jul 13 2026
F8010 Annexin A10/ANXA10 Antibody (Rabbit mAb) [J2G3] Jul 13 2026
F7077 TPX2 Antibody (Rabbit mAb) [C1B23] Jul 13 2026
F9907 CRX Antibody (Rabbit mAb) [F1B1] Jul 13 2026
F9288 WIP1 Antibody (Rabbit mAb) [J2N2] Jul 13 2026
F8623 UBE2C Antibody (Rabbit mAb) [G9E18] Jul 13 2026
F9677 EAAT3 Antibody (Rabbit mAb) [A15N21] Jul 13 2026
F8992 FABP5 Antibody (Rabbit mAb) [N18C4] Jul 13 2026
F7306 RALBP1 Antibody (Rabbit mAb) [G20F10] Jul 13 2026
F6849 DCAMKL1 Antibody (Rabbit mAb) [P14A13] Jul 13 2026
F8824 SMN Antibody (Rabbit mAb) [C8K16] Jul 13 2026
F5886 TRADD Antibody (Rabbit mAb) [F18K8] Jul 13 2026
F9179 PSRC2 Antibody (Rabbit mAb) [L8L24] Jul 13 2026
F7478 Lin28B Antibody (Rabbit mAb) [J18A6] Jul 13 2026
F5690 mH2A1 Antibody (Rabbit mAb) [E22M7] Jul 13 2026
F3274 LINE-1 ORF1p Antibody (Mouse mAb) [M4G2] Jul 13 2026
F6203 SMARCA1 Antibody (Rabbit mAb) [N5C5] Jul 13 2026
F9488 XPB Antibody (Rabbit mAb) [D23K21] Jul 13 2026
F6700 PHC1 Antibody (Mouse mAb) [F8N11] Jul 13 2026
F7944 Galectin 3 Antibody (Rabbit mAb) [K11P7] Jul 13 2026
F9047 DC-SIGNR Antibody (Rabbit mAb) [N17H7] Jul 13 2026
F9486 MEK2 Antibody (Rabbit mAb) [C14M9] Jul 13 2026
F2416 ADRA1B Antibody (Rabbit mAb) [C3A12] Jul 13 2026
F6397 A-Raf Antibody (Rabbit mAb) [M11A1] Jul 13 2026
F8324 Caspase-4 Antibody (Rabbit mAb) [N6J21] Jul 13 2026
F9057 E2A Antibody (Rat mAb) [K20N18] Jul 13 2026
F6102 IFITM1 Antibody (Rabbit mAb) [E10P18] Jul 13 2026
F9110 DDX41 Antibody (Rabbit mAb) [N10L11] Jul 13 2026
F8485 Caveolin-2 Antibody (Rabbit mAb) [E6A6] Jul 13 2026
F3938 ANK-3 Antibody (Mouse mAb) [F22J23] Jul 13 2026
F8527 TRRAP Antibody (Rabbit mAb) [B19L10] Jul 13 2026
F6510 RNF40 Antibody (Rabbit mAb) [A17P16] Jul 13 2026
F7603 SOCS2 Antibody (Rabbit mAb) [H21H24] Jul 13 2026
F8813 PABP1 Antibody (Mouse mAb) [G23P5] Jul 13 2026
F2445 HOXA9 Antibody (Rabbit mAb) [A6N14] Jul 13 2026
F2596 TIA1 Antibody (Rabbit mAb) [A18M15] Jul 13 2026
F2458 Cyclin A1 + A2 Antibody (Rabbit mAb) [N12H18] Jul 13 2026
F5935 Perilipin-2 Antibody (Rabbit mAb) [K24J8] Jul 13 2026
F5133 HNRNPF Antibody (Mouse mAb) [C13B21] Jul 13 2026
F9010 p38β/MAPK11 + p38α/MAPK14 Antibody (Rabbit mAb) [M11B5] Jul 13 2026
F9381 Cdc20 Antibody (Rabbit mAb) [L21M22] Jul 13 2026
F5491 Choline Acetyltransferase Antibody (Rabbit mAb) [N24K12] Jul 13 2026
F5224 Islet 1 Antibody (Rabbit mAb) [K5C1] Jul 13 2026
F6227 Histone H1.0 Antibody (Rabbit mAb) [G10M9] Jul 13 2026
F9862 Occludin Antibody (Rabbit mAb) [L16J4] Jul 13 2026
F8662 Cyclophilin F Antibody (Rabbit mAb) [E22D20] Jul 13 2026
F6085 MRP2 / ABCC2 Antibody (Rabbit mAb) [H11G14] Jul 13 2026
F8251 TGF β Receptor II Antibody (Rabbit mAb) [L17N10] Jul 13 2026
F5483 SMCR7L/MID51 Antibody (Mouse mAb) [L21F3] Jul 13 2026
F9540 VPS15 Antibody (Rabbit mAb) [A22G22] Jul 13 2026
F7305 TRP1 Antibody (Rabbit mAb) [B22H9] Jul 13 2026
F8999 ATP5A Antibody (Rabbit mAb) [H6A8] Jul 13 2026
F5369 ACO2 Antibody (Rabbit mAb) [E24J9] Jul 13 2026
F5817 Sall4 Antibody (Mouse mAb) [D8D9] Jul 13 2026
F8108 SDHB Antibody (Rabbit mAb) [P15D13] Jul 13 2026
F3120 Rab11A Antibody (Mouse mAb) [C20H15] Jul 13 2026
F3743 Apolipoprotein B Antibody (Rabbit mAb) [E23K19] Jul 13 2026
F4111 Phospho-RIP3 (Thr231/Ser232) Antibody (Rabbit mAb) [N16H18] Jul 13 2026
F4359 CFTR Antibody (Mouse mAb) [P23G6] Jul 13 2026
F5026 BSCL2/Seipin Antibody (Rabbit mAb) [N16E20] Jul 13 2026
F3869 SCP1 Antibody (Rabbit mAb) [D5M24] Jul 13 2026
F1412 Phospho-FoxM1 (Thr600) Antibody (Rabbit mAb) [A10D13] Jul 13 2026
F4759 TET2 Antibody (Rabbit mAb) [H24A10] Jul 13 2026
F8755 Phospho-RelB (Ser552) Antibody (Rabbit mAb) [C17L2] Jul 13 2026
F2610 CD39 Antibody (Rabbit mAb) [A7P6] Jul 13 2026
E6678 PRT3645 PRT3645 is a brain-penetrant CDK4/6 inhibitor that exhibits single-digit nanomolar biochemical potency against CDK4/6 and >2,000-fold selectivity against other CDK family members (CDK1, CDK2, and CDK9). PRT3645 exhibits anti-cell proliferation in glioblastoma (GBM) cell lines and in HER2− and HER2+ breast cancer lines (EC50 of < 125 nM), and demonstrates anti-tumor activity and enhances survival in glioblastoma and breast cancer brain metastasis models. Jul 13 2026
F5038 BRCA1 Antibody (Rabbit mAb) [D2H19] Jul 13 2026
F5047 MUC1 Antibody (Mouse mAb) [E9C17] Jul 13 2026
F1161 Pax2 Antibody (Rabbit mAb) [N14F20] Jul 13 2026
F4715 DNA-PKcs Antibody (Rabbit mAb) [H12B18] Jul 13 2026
F2630 Phospho-PDGFR α/β (Tyr849/Tyr857) Antibody (Rabbit mAb) [B8C12] Jul 13 2026
F4150 TAZ/YAP Antibody (Rabbit mAb) [B1F12] Jul 13 2026
F8229 DAG Lipase α Antibody (Rabbit mAb) [D2E6] Jul 13 2026
F9992 Brachyury/Bry Antibody (Rabbit mAb) [K13E20] Jul 13 2026
F7179 Phospho-ULK1 (Ser638) Antibody (Rabbit mAb) [F14B19] Jul 13 2026
F7190 Semaphorin 7A Antibody (Rat mAb) [E19F6] Jul 13 2026
F1866 Glu-Glu Epitope Tag Antibody (Mouse mAb) [N24M2] Jul 13 2026
F6170 N6-Methyladenosine/m6A Antibody (Rabbit mAb) [B12K9] Jul 13 2026
F7874 CXCL9 Antibody (Rabbit mAb) [L15N2] Jul 13 2026
F5661 SOAT1/ACAT1 Antibody (Rabbit mAb) [E19E10] Jul 13 2026
F5650 BAF57/SMARCE1 Antibody (Rabbit mAb) [B6L12] Jul 13 2026
F2795 Pumilio 2 Antibody (Rabbit mAb) [P14B5] Jul 13 2026
F0397 Phospho-HER4/ErbB4 (Tyr1284)/EGFR (Tyr1173) Antibody (Rabbit mAb) [D10B7] Jul 13 2026
F5781 TER-119 Antibody (Rat mAb) [H18E16] Jul 13 2026
E6879 Carboxyethylgermanium sesquioxide Carboxyethylgermanium sesquioxide（Repagermanium, DMX-200) is an orally active small‑molecule inhibitor of the C‑C chemokine receptor type 2 (CCR2) pathway and is used in combination with an angiotensin receptor blocker (ARB) to reduce proteinuria and slow kidney function decline in proteinuric chronic kidney diseases such as focal segmental glomerulosclerosis (FSGS). Jul 12 2026
E4644 AMXT-1501 AMXT-1501 is a bacterial agent and polyamine transport system inhibitor that targets membrane phospholipids and exhibits antibacterial activity against a variety of Gram-positive and Gram-negative multidrug-resistant bacteria. AMXT-1501 inhibits capsular biosynthesis in Streptococcus pneumoniae by disrupting polyamine homeostasis and downregulating capsule-associated biosynthesis pathways. Jul 09 2026
E6786 MMP408 MMP408 is a selective and orally active inhibitor of MMP-12 with IC50 for human, mouse, and rat MMP-12 of 2 nM, 160 nM, and 3 μM, respectively. MMP408 also exhibits an IC50 for human MMP-13 of 120 nM, and its activity against other MMPs is weak. It exhibits the potential to be used in research of chronic obstructive pulmonary disease (COPD) and chronic sinusitis with nasal polyps. Jul 07 2026
E6781 IAM1363 IAM1363 is a selective, irreversible, brain-penetrant inhibitor of Type II HER2, which prevents phosphorylation and activation of wild-type HER2 and variants with activating mutations in the tyrosine kinase domain. It also exhibits effective treatment for HER2 amplified or mutant NSCLC patients, including for patients with CNS metastases. Jul 05 2026
E1094 Enlicitide decanoate Enlicitide (MK‑0616) decanoate is an orally active macrocyclic peptide PCSK9 inhibitor that binds PCSK9, blocks its interaction with the low‑density lipoprotein receptor (LDLR), and thereby enhances hepatic clearance of LDL‑C. It reduces atherogenic lipoproteins, including non‑HDL cholesterol, apolipoprotein B, and lipoprotein(a) in hypercholesterolemic and HeFH patients. Jul 05 2026
E6836 Yhhu-3792 hydrochloride Yhhu-3792 hydrochloride is a Notch activator that enhances the self-renewal capability of neural stem cells (NSCs) and promotes the expression of Hes3 and Hes5. It increases the spatial and episodic memory abilities of mice by expanding the NSC pool and promoting endogenous neurogenesis in the hippocampal dentate gyrus. It exhibits potential to be used in the study of neurodegenerative diseases such as Alzheimer's disease, or for neural regeneration after brain injury. Jul 05 2026
E6777 RA-0002034 RA-0002034 (RA-2034) is a covalent fragment containing a vinyl sulfone warhead that inhibits CHIKV nsP2 protease (nsP2pro) with an IC50 of 58 nM and shows broad-spectrum anti-alphavirus activity through targeted inhibition of nsP2pro. Jun 30 2026
E0870 TPE-MI TPE-MI (tetraphenylethene maleimide) is a thiol-reactive probe for measuring unfolded protein load and proteostasis in cells (excitation 350 nm, emission 470 nm). It exhibits proteostasis imbalance in induced pluripotent stem cell models of Huntington disease and in cells transfected with mutant huntingtin exon 1 before visible aggregate formation, and it detects protein damage following dihydroartemisinin treatment of Plasmodium falciparum. Jun 30 2026
E1763 Voxilaprevir Voxilaprevir  (GS-9857) is a noncovalent, reversible HCV NS3/4A protease inhibitor with pangenotypic antiviral activity. It inhibits genotype 1b and 3a wild-type NS3 proteases with Ki of 0.038 nM and 0.066 nM, respectively, and is used for HCV infection research. Jun 30 2026
E6800 liradasertib Liradasertib (DNL151, BIIB122) is a selective, orally bioavailable, CNS-penetrant LRRK2 inhibitor that exhibits promising therapeutic approach for the treatment of Parkinson's disease (PD). Jun 30 2026
P1284 Degarelix Degarelix (FE 200486 free base) is a water-soluble GnRH antagonist with an IC50 of 3 nM. It exhibits profound and sustained suppression of testosterone in patients with prostate cancer. Jun 30 2026
E6552 LRK-4189 LRK-4189 is an orally active PIP4K2C degrader, which induces degradation of the lipid kinase PIP4K2C, triggers interferon signaling in microsatellite-stable colorectal cancer cells, promotes immunogenic tumor killing and endogenous cell death, and sensitizes MSS colorectal tumors to NK-cell killing and dendritic-cell phagocytosis. Jun 30 2026
E5938 CW-3308 CW-3308 is a potent, selective, orally bioavailable BRD9 degrader that acts through a CRBN-recruiting PROTAC mechanism and effectively inhibits HS-SY-II xenograft tumor growth in vivo. Jun 28 2026
E6489 AZD9750 AZD9750 is an orally bioavailable, CRBN-recruiting androgen receptor PROTAC degrader that induces proteasome-dependent degradation of wild-type AR and resistant AR mutants, inhibits AR signaling, and suppresses prostate cancer xenograft tumor growth in vivo. Jun 28 2026
E6831 Gintemetostat KTX-1001 (Gintemetostat) is an orally active and specific NSD2/MMSET histone methyltransferase inhibitor with human NSD2 IC50 of 0.460 (0.040) nM and 2.32 (0.47) nM for the SET domain. It also enhances immunomodulatory and immune-directed therapies in preclinical models of multiple myeloma. Jun 28 2026
E6688 CNT2198 CNT2198 is an orally bioavailable small-molecule inhibitor of DES1 (dihydroceramide desaturase 1) that reduces renal tubular injury, lowers BUN and plasma creatinine, preserves mitochondrial morphology, and exhibits potential for preventing acute kidney injury. Jun 28 2026
E6443 6PPD-Q 6PPD-Q (6PPD-Quinone) is a substituted p‑phenylenediamine (PPD) quinone, the oxidized transformation product of the tire rubber antioxidant 6‑PPD, and is recognized as an environmental toxicant. Jun 28 2026
E6537 Eras-4001 ERAS-4001 is a pan-KRAS inhibitor with potent antitumor activity. It inhibits proliferation of wild-type and mutant KRAS-driven cancer cells, including KRAS G12D, G12V, and G12C, and suppresses tumor growth in GP2D and Panc0403 xenograft mouse models. Jun 25 2026
E6439 IR-780 IR‑780 is a lipophilic heptamethine cyanine NIR dye that preferentially accumulates in tumor cells. It exhibits excitation/emission maxima around 780/799 nm and localizes predominantly to mitochondria in malignant cells. Jun 25 2026
E1233 Rezvilutamide Rezvilutamide (SHR3680) is an orally bioavailable and second-generation antagonist of androgen receptor (AR) that competitively binds to androgen receptors, preventing receptor activation and blocking the transcription of genes that fuel prostate cancer cell proliferation. Jun 25 2026
A2180 Anti-Mouse δ-like protein 1 (DLL1)-Invivo [HMD1-5] Anti-Mouse δ-like protein 1 (DLL1)-Invivo [HMD1-5] reacts with mouse δ-like protein 1 (DLL1) one of many Notch ligands. DLL1 is expressed by thymic and splenic stromal cells, macrophages, and dendritic cells. Jun 23 2026
E5981 Coppersensor 1 Coppersensor-1 is a membrane-permeable fluorescent dye with picomolar affinity for Cu+ and high selectivity over other cellular metal ions. It enables selective and sensitive detection of copper(I) in biological samples, including live cells, and has been used to study copper-related processes in cancer, cardiovascular, and neurodegenerative disease research. Jun 21 2026
E6782 BHV-2100 BHV-2100 is a potent, selective, peripherally restricted, orally administered, first-in-class antagonist of TRPM3 with IC50 between 1–10 nM. It also reduces pain in preclinical models without thermoregulatory or sedative effects. Jun 16 2026
E6525 AMXT-1501 tetrahydrochloride AMXT-1501 tetrahydrochloride is an orally bioavailable polyamine transport inhibitor that works synergistically with DFMO to starve cancer cells, simultaneously blocking their internal polyamine production and external import. In preclinical models, closing both pathways produced strong antitumor activity and signs of restored anti-tumor immune response. Jun 16 2026
E4718 IRG1-IN-1 IRG1-IN-1 is a potent inhibitor of IRG1. Through targeted pharmacologic blockade, it reverses tumor-associated macrophage (TAM)-mediated PARP inhibitor (PARPi) resistance, synergizing with PARPi to suppress tumor growth across multiple immunocompetent models of BRCA1-deficient breast cancer. Jun 16 2026
E4748 EOS-984 EOS-984 (EOS301984) is a potent antagonist of ENT1 that restores pyrimidine levels in activated T cells within adenosine-rich environments. This metabolic rescue enhances tumor cell killing by memory T cells and increases the ex vivo expansion of functional human tumor-infiltrating lymphocytes (TILs). Jun 16 2026
E1454 Phosphoramide mustard cyclohexanamine Phosphoramide mustard cyclohexanamine is the stabilized and biologically active cytotoxic metabolite of the prodrug cyclophosphamide that acts as a potent DNA alkylator. It selectively binds the N-7 position of guanine residues to generate cytotoxic mono- and bi-functional DNA adducts. These cross-links physically stall replication forks and trigger the ATM/gammaH2AX DNA damage response pathway, effectively driving malignant cells into apoptosis. Jun 11 2026
E5884 DNA2 inhibitor C5 DNA2 inhibitor C5 (NSC-15765) is a potent, competitive, and specific DNA2 nuclease inhibitor with an IC50 of 20 μM. By targeting an allosteric pocket near the DNA-binding site, it comprehensively shuts down the multi-catalytic functions of DNA2—effectively suppressing its nuclease, DNA-dependent ATPase, helicase, and direct DNA-binding activities. Jun 10 2026
E4689 Nrf2-IN-1 Nrf2-IN-1 (Compound 4f) is a potent pyrazolyl hydroxamic acid derivative and specific inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2). By downregulating Nrf2 protein levels and blocking the downstream Nrf2-ARE antioxidant signaling pathway, it disrupts cellular redox homeostasis. Jun 10 2026
F3803 Pin1 Antibody (Mouse mAb) [C4H20] Jun 09 2026
F2683 NeuN Antibody (Mouse mAb) [E22E10] Jun 09 2026
F1570 NUP153 Antibody (Mouse mAb) [L18J13] Jun 09 2026
F3389 RBPSUH Antibody (Rabbit mAb) [M13J4] Jun 09 2026
F6608 IL-2 Antibody (Rabbit mAb) [G3L7] Jun 09 2026
F6702 NLK Antibody (Rabbit mAb) [D1D21] Jun 09 2026
F9097 CD163 Antibody (Rabbit mAb) [P6H23] Jun 09 2026
F3641 NEK6 Antibody (Rabbit mAb) [P9K17] Jun 09 2026
F6825 β IV Tubulin Antibody (Mouse mAb) [A2G2] Jun 09 2026
F6483 PKC β Antibody (Rabbit mAb) [C22A12] Jun 09 2026
F7890 NKp46/NCR1 Antibody (Mouse mAb) [K17G8] Jun 09 2026
F9828 BMP-1/PCP Antibody (Rat mAb) [D9N3] Jun 09 2026
F7230 NOX4 Antibody (Rabbit mAb) [M9N20] Jun 09 2026
F8794 CX3CR1 Antibody (Rabbit mAb) [G13H18] Jun 09 2026
F6729 TRAF4 Antibody (Mouse mAb) [N23M6] Jun 09 2026
F3179 DIAPH1 Antibody (Rabbit mAb) [J8A16] Jun 09 2026
F6238 Calponin 1 Antibody (Rabbit mAb) [B15N12] Jun 09 2026
F6080 CXCL2 Antibody (Rabbit mAb) [H18N1] Jun 09 2026
F4630 NY-ESO-1 Antibody (Rabbit mAb) [D2K7] Jun 09 2026
F5972 AP-2α Antibody (Rabbit mAb) [H2P15] Jun 09 2026
F2913 COX6B1 Antibody (Rabbit mAb) [J13A19] Jun 09 2026
F3671 MST3 Antibody (Rabbit mAb) [F21L14] Jun 09 2026
F4915 MRP1/ABCC1 Antibody (Rabbit mAb) [M22C19] Jun 09 2026
F4937 MEKK1 Antibody (Mouse mAb) [B14N1] Jun 09 2026
F6871 RIF1 Antibody (Rabbit mAb) [L2M1] Jun 09 2026
F4934 Ribosomal Protein S7 Antibody (Mouse mAb) [E20M7] Jun 09 2026
F5574 Aggrecan Antibody (Rabbit mAb) [M12J8] Jun 09 2026
F4505 SmarcAL1 Antibody (Mouse mAb) [K9N14] Jun 09 2026
F4489 Gαi-1/GNAI1 Antibody (Mouse mAb) [B24D21] Jun 09 2026
F4491 FZR1 Antibody (Mouse mAb) [E11J24] Jun 09 2026
F2207 Osteopontin Antibody (Rabbit mAb) [K22J24] Jun 09 2026
F4710 FKBP5 Antibody (Rabbit mAb) [J11H16] Jun 09 2026
F8638 NM23A Antibody (Rabbit mAb) [E3D15] Jun 09 2026
F9368 PSMC2 Antibody (Mouse mAb) [A15H16] Jun 09 2026
F7665 CDK12 Antibody (Rabbit mAb) [N24C20] Jun 09 2026
F5249 GCN1 Antibody (Rabbit mAb) [G16A4] Jun 09 2026
F8354 N myc interactor/NMI Antibody (Rabbit mAb) [B12H19] Jun 09 2026
F7762 MafA Antibody (Rabbit mAb) [N21K22] Jun 09 2026
F6897 OGDH Antibody (Rabbit mAb) [L20G5] Jun 09 2026
F4204 CDC42 Antibody (Rabbit mAb) [B14M24] Jun 09 2026
F4261 NEDD4-L Antibody (Mouse mAb) [P22P8] Jun 09 2026
F3302 FMNL2 Antibody (Mouse mAb) [A6K4] Jun 09 2026
F6803 YKL-40/CHI3L1 Antibody (Rabbit mAb) [M13C3] Jun 09 2026
F5605 Myosin IIb Antibody (Rabbit mAb) [F18M11] Jun 09 2026
F7174 NSD3 Antibody (Rabbit mAb) [D12B18] Jun 09 2026
F0518 Phospho-Akt1 (Ser473) Antibody (Rabbit mAb) [E4M2] Jun 09 2026
F1198 Mer Antibody (Rabbit mAb) [C10E14] Jun 09 2026
F4314 MIRAB13 Antibody (Mouse mAb) [F12J3] Jun 09 2026
F5166 NKCC1 Antibody (Rabbit mAb) [A2N20] Jun 09 2026
F4733 β Amyloid (Aβ) 1-42 Antibody (Rabbit mAb) [N17C24] Jun 09 2026
F6082 IFI16 Antibody (Rabbit mAb) [E2M12] Jun 09 2026
F9887 Cdk8 Antibody (Rabbit mAb) [G17E8] Jun 09 2026
F8230 MBNL2 Antibody (Mouse mAb) [H9D23] Jun 09 2026
F7048 Cullin 4B/CUL-4B Antibody (Rabbit mAb) [J23G17] Jun 09 2026
F7344 Swd2 Antibody (Rabbit mAb) [L22F8] Jun 09 2026
F9557 BRE Antibody (Rabbit mAb) [F1N20] Jun 09 2026
F5138 Tubulin β Class V Antibody (Mouse mAb) [P1M16] Jun 09 2026
F8335 NMNAT-1 Antibody (Mouse mAb) [H16N17] Jun 09 2026
F8820 Cytochrome P450 Reductase Antibody (Rabbit mAb) [A13P3] Jun 09 2026
F1107 DLAT Antibody (Rabbit mAb) [L23H19] Jun 09 2026
F8033 DDX6 Antibody (Rabbit mAb) [J2G17] Jun 09 2026
F2889 Perilipin-1 Antibody (Rabbit mAb) [B3G1] Jun 09 2026
F0953 OAS1 Antibody (Rabbit mAb) [N5C17] Jun 09 2026
F4792 SDF-1 Antibody (Rabbit mAb) [M4G11] Jun 09 2026
F3026 COL3A1 Antibody (Rabbit mAb) [P18A14] Jun 09 2026
F4601 Phospho-MLKL (Ser358) Antibody (Rabbit mAb) [K9E15] Jun 09 2026
F4969 Phospho-eIF4G (Ser1108) Antibody (Rabbit mAb) [G15K10] Jun 09 2026
F9999 CXCL13 Antibody (Mouse mAb) [E8F3] Jun 09 2026
F9902 Phospho-DDR1 (Tyr513) Antibody (Rabbit mAb) [F16D7] Jun 09 2026
F5804 Phospho-Cyclin B1 (Ser133) Antibody (Rabbit mAb) [K22L23] Jun 09 2026
F4769 Tachykinin-3 Antibody (Mouse mAb) [K4A12] Jun 09 2026
F6955 Ras (G12D Mutant) Antibody (Rabbit mAb) [C11A12] Jun 09 2026
F7369 PREX1 Antibody (Rabbit mAb) [J20N16] Jun 09 2026
F9077 HGF β Antibody (Rabbit mAb) [F7L16] Jun 09 2026
F6254 PLK2 Antibody (Rabbit mAb) [M21F17] Jun 09 2026
F0597 Phospho-JAK2 (Tyr1007) Antibody (Rabbit mAb) [G9F22] Jun 09 2026
F3822 TGN46 Antibody (Mouse mAb) [H8C2] Jun 09 2026
F8636 Phospho-Estrogen Receptor α (Ser167) Antibody (Rabbit mAb) [D20F17] Jun 09 2026
F9976 Cannabinoid receptor 2 Antibody (Rabbit mAb) [G5B22] Jun 09 2026
F8922 ACE2 Antibody (Rabbit mAb) [P24F5] Jun 09 2026
F6522 Cathepsin L Antibody (Mouse mAb) [E18C8] Jun 09 2026
F5087 GYG1 Antibody (Mouse mAb) [E16D17] Jun 09 2026
F4996 MAFA Antibody (Rabbit mAb) [N15J3] Jun 09 2026
F9678 VEGF Receptor 3 Antibody (Rabbit mAb) [M6F2] Jun 09 2026
F9739 CCL3/MIP-1α Antibody (Rabbit mAb) [C14E20] Jun 09 2026
F9354 USP9X Antibody (Rabbit mAb) [H15M1] Jun 09 2026
F1604 Fast Myosin Skeletal Heavy chain Antibody (Mouse mAb) [A10L9] Jun 09 2026
F9991 IκB-ζ Antibody (Rabbit mAb) [K24D5] Jun 09 2026
F1599 Aggrecan Antibody (Mouse mAb) [D23A4] Jun 09 2026
F9855 Endomucin Antibody (Rabbit mAb) [J13M21] Jun 09 2026
F9404 mCherry Antibody (Rabbit mAb) [P15F10] Jun 09 2026
F8612 mGluR5 Antibody (Rabbit mAb) [D5P24] Jun 09 2026
F5434 HMGCS1 Antibody (Rabbit mAb) [D13C18] Jun 09 2026
F6378 Phospho-ATGL (Ser406) Antibody (Rabbit mAb) [B14A21] Jun 09 2026
F0013 ZO1 tight junction protein Antibody (Rabbit mAb) [C21G5] Jun 09 2026
F5452 LDH-B Antibody (Rabbit mAb) [D9J11] Jun 09 2026
F5602 DBC1 Antibody (Rabbit mAb) [E8N20] Jun 09 2026
F5263 PKMYT1 Antibody (Rabbit mAb) [E20E14] Jun 09 2026
F1613 Endothelin 1 Antibody (Mouse mAb) [F2J1] Jun 09 2026
F2200 Phospho-RSK1 p90 (Thr573) Antibody (Rabbit mAb) [L22G7] Jun 09 2026
F4394 α Cardiac Actin Antibody (Mouse mAb) [J1E19] Jun 09 2026
F4870 Phospho-PLK1 (Thr210) Antibody (Rabbit mAb) [K10L6] Jun 09 2026
F4978 SLC2A9 Antibody (Mouse mAb) [D8G2] Jun 09 2026
F5135 RPL3 Antibody (Mouse mAb) [H7C5] Jun 09 2026
F0991 DMT1/SLC11A2 Antibody (Mouse mAb) [G3J24] Jun 09 2026
F3510 Phospho-Tyrosine Antibody (Mouse mAb) [N16H13] Jun 09 2026
F4382 Neurofilament-M/H Antibody (Mouse mAb) [G10L12] Jun 09 2026
F2251 Rad50 Antibody (Mouse mAb) [P20A20] Jun 09 2026
F4529 AHA1 Antibody (Rat mAb) [L18K15] Jun 09 2026
F4557 Hepatic Sinusoidal Endothelial Cell Antibody (Mouse mAb) [L23C8] Jun 09 2026
F4806 APC8 Antibody (Rabbit mAb) [E8M5] Jun 09 2026
F4841 Peroxiredoxin 1/PAG Antibody (Rabbit mAb) [N9K11] Jun 09 2026
F4946 NUP98 (Nuclear Pore Marker) Antibody (Rat mAb) [L2D21] Jun 09 2026
F4950 GOLPH3 Antibody (Mouse mAb) [L14M1] Jun 09 2026
F5130 EEF1D Antibody (Mouse mAb) [G11C24] Jun 09 2026
F1546 TMEM119 (Microglial Marker) Antibody (Rabbit mAb) [H12P23] Jun 09 2026
F4341 Siglec-1/CD169 Antibody (Mouse mAb) [E18B9] Jun 09 2026
F4533 Langerin/CD207 Antibody (Rat mAb) [F3M20] Jun 09 2026
F4837 Phospho-SQSTM1/p62 (Ser349) Antibody (Rabbit mAb) [N16A3] Jun 09 2026
F5109 SDC2 Antibody (Mouse mAb) [D5J9] Jun 09 2026
E6808 PRLX-93936 hydrochloride PRLX-93936 hydrochloride is a potent molecular glue degrader that selectively binds to E3 ubiquitin ligase TRIM21 and forms a functional ternary complex between TRIM21 and NUP98 (Nucleoporin 98). This complex formation drives the subsequent polyubiquitination and proteasomal degradation of NUP98 alongside other essential components of the nuclear pore complex (NPC). Jun 08 2026
E6809 JWZ-8-103 JWZ-8-103 is an orally bioavailable selective degrader of the nuclear pore complex that acts as a TRIM21-targeting molecular glue. It induces a robust TRIM21 PRYSPRY–NUP98 APD interaction with an apparent EC50 ≈ 20 µM and increases TRIM21 thermal stability. It also exhibits potent antitumor efficacy in pancreatic cancer xenografts and patient-derived organoids. Jun 08 2026
E6731 Tacaciclib Tacaciclib (AUR-102, XL-102) is a specific and orally bioavailable covalent inhibitor of CDK7 with an IC50 of 12 nM, 5 nM and 0.9 nM for 20, 60 and 180 min, respectively. It also induces apoptosis in AML cells via CDK7/c-Myc/p53 axis. Jun 08 2026
E6719 IID432 IID432 is a highly efficacious and safe oral cyanotriazole inhibitor of Trypanosoma cruzi topoisomerase II, with an EC50 of 8 nM. It achieved relapse-free (sterile) parasite clearance in wash-out assays and a single 25 mg/kg dose cleared infection in mice. IID432 has potential as a curative, short-course treatment for Chagas disease. Jun 08 2026
E6555 Alogabat Alogabat (RG-7816; RO-7017773) is a positive allosteric modulator (PAM) of the GABAA α5 receptor, with a ki of 7.9 nM for α5β3γ2 subunit. It enhances GABA-evoked responses at α5-containing receptors and shows antiseizure activity without cognitive/sedative impairment at therapeutic doses. Jun 08 2026
S7945 Echinomycin (Quinomycin A) Echinomycin (Quinomycin A;NSC-13502) is a potent, cell‑permeable inhibitor of HIF‑1–mediated gene transcription that bis‑intercalates into DNA in a sequence‑specific manner, thereby blocking HIF‑1α/β binding to hypoxia‑responsive elements and reversibly inhibiting hypoxia‑induced HIF‑1 transcriptional activity in U251‑HRE cells with an EC50 of approximately 1.2 nM. Jun 08 2026
E5937 AK-1690 AK‑1690 is a selective PROTAC degrader of STAT6 (DC50 ≈ 1 nM) that recruits STAT6 to cereblon, inducing its ubiquitin‑dependent proteasomal degradation in cells and tissues. Jun 08 2026
E6691 SIRT4-IN-1 SIRT4-IN-1 (Compound 69) is a potent, cell-permeable small-molecule inhibitor of Sirtuin 4 (Sirt4) with an IC50 of 16 μM against human Sirt4 (hSirt4). It also acts as a competitive inhibitor of acyl peptide substrate, binding directly within the Sirt4 acyl-binding pocket and noncompetitive with the NAD+ cofactor. SIRT4-IN-1 treatment effectively increases glutamate dehydrogenase (GDH) activity and rescues pyruvate dehydrogenase (PDH) activity. Jun 07 2026
E6689 Pociredir Pociredir(FTX-6058) is a potent, orally bioavailable inhibitor of Embryonic Ectoderm Development (EED), a core regulatory subunit of the polycomb repressive complex 2 (PRC2). By disrupting this epigenetic mechanism, the compound downregulates key fetal globin repressors to robustly induce fetal hemoglobin (HbF) protein expression in both cellular and murine models. Jun 07 2026
F2665 Rabbit IgG Isotype Control Antibody (Rabbit mAb) [D24D4] Jun 07 2026
E6510 LOXO-435 Jun 03 2026
E1852 RLY-2608 RLY‑2608 (zovegalisib) is an oral, first‑in‑class allosteric, pan‑mutant‑selective inhibitor of PI3Kα that preferentially targets oncogenic PIK3CA mutants, retaining antitumor activity while reducing PI3Kα‑related metabolic toxicities. Jun 03 2026
E1309 AP39 AP39 is a triphenylphosphonium‑derivatised anethole dithiolethione and a mitochondria‑targeted hydrogen sulfide (H₂S) donor that increases intracellular, particularly mitochondrial, H₂S levels. AP39 also preserves mitochondrial DNA integrity under oxidative stress and protects against myocardial reperfusion injury in mice. Jun 02 2026