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All New Products Listed Chronologically

製品コード 製品名称 製品説明 添加時期
E6777 RA-0002034 RA-0002034 (RA-2034) is a covalent fragment containing a vinyl sulfone warhead that inhibits CHIKV nsP2 protease (nsP2pro) with an IC50 of 58 nM and shows broad-spectrum anti-alphavirus activity through targeted inhibition of nsP2pro. Jun 30 2026
E0870 TPE-MI TPE-MI (tetraphenylethene maleimide) is a thiol-reactive probe for measuring unfolded protein load and proteostasis in cells (excitation 350 nm, emission 470 nm). It exhibits proteostasis imbalance in induced pluripotent stem cell models of Huntington disease and in cells transfected with mutant huntingtin exon 1 before visible aggregate formation, and it detects protein damage following dihydroartemisinin treatment of Plasmodium falciparum. Jun 30 2026
E1763 Voxilaprevir Voxilaprevir  (GS-9857) is a noncovalent, reversible HCV NS3/4A protease inhibitor with pangenotypic antiviral activity. It inhibits genotype 1b and 3a wild-type NS3 proteases with Ki of 0.038 nM and 0.066 nM, respectively, and is used for HCV infection research. Jun 30 2026
E6800 liradasertib Liradasertib (DNL151, BIIB122) is a selective, orally bioavailable, CNS-penetrant LRRK2 inhibitor that exhibits promising therapeutic approach for the treatment of Parkinson's disease (PD). Jun 30 2026
P1284 Degarelix Degarelix (FE 200486 free base) is a water-soluble GnRH antagonist with an IC50 of 3 nM. It exhibits profound and sustained suppression of testosterone in patients with prostate cancer. Jun 30 2026
E6552 LRK-4189 LRK-4189 is an orally active PIP4K2C degrader, which induces degradation of the lipid kinase PIP4K2C, triggers interferon signaling in microsatellite-stable colorectal cancer cells, promotes immunogenic tumor killing and endogenous cell death, and sensitizes MSS colorectal tumors to NK-cell killing and dendritic-cell phagocytosis. Jun 30 2026
E5938 CW-3308 CW-3308 is a potent, selective, orally bioavailable BRD9 degrader that acts through a CRBN-recruiting PROTAC mechanism and effectively inhibits HS-SY-II xenograft tumor growth in vivo. Jun 28 2026
E6489 AZD9750 AZD9750 is an orally bioavailable, CRBN-recruiting androgen receptor PROTAC degrader that induces proteasome-dependent degradation of wild-type AR and resistant AR mutants, inhibits AR signaling, and suppresses prostate cancer xenograft tumor growth in vivo. Jun 28 2026
E6831 Gintemetostat KTX-1001 (Gintemetostat) is an orally active and specific NSD2/MMSET histone methyltransferase inhibitor with human NSD2 IC50 of 0.460 (0.040) nM and 2.32 (0.47) nM for the SET domain. It also enhances immunomodulatory and immune-directed therapies in preclinical models of multiple myeloma. Jun 28 2026
E6688 CNT2198 CNT2198 is an orally bioavailable small-molecule inhibitor of DES1 (dihydroceramide desaturase 1) that reduces renal tubular injury, lowers BUN and plasma creatinine, preserves mitochondrial morphology, and exhibits potential for preventing acute kidney injury. Jun 28 2026
E6443 6PPD-Q 6PPD-Q (6PPD-Quinone) is a substituted p‑phenylenediamine (PPD) quinone, the oxidized transformation product of the tire rubber antioxidant 6‑PPD, and is recognized as an environmental toxicant. Jun 28 2026
E6537 Eras-4001 ERAS-4001 is a pan-KRAS inhibitor with potent antitumor activity. It inhibits proliferation of wild-type and mutant KRAS-driven cancer cells, including KRAS G12D, G12V, and G12C, and suppresses tumor growth in GP2D and Panc0403 xenograft mouse models. Jun 25 2026
E6439 IR-780 IR‑780 is a lipophilic heptamethine cyanine NIR dye that preferentially accumulates in tumor cells. It exhibits excitation/emission maxima around 780/799 nm and localizes predominantly to mitochondria in malignant cells. Jun 25 2026
E1233 Rezvilutamide Rezvilutamide (SHR3680) is an orally bioavailable and second-generation antagonist of androgen receptor (AR) that competitively binds to androgen receptors, preventing receptor activation and blocking the transcription of genes that fuel prostate cancer cell proliferation. Jun 25 2026
A2180 Anti-Mouse δ-like protein 1 (DLL1)-Invivo Jun 23 2026
E5981 Coppersensor 1 Coppersensor-1 is a membrane-permeable fluorescent dye with picomolar affinity for Cu+ and high selectivity over other cellular metal ions. It enables selective and sensitive detection of copper(I) in biological samples, including live cells, and has been used to study copper-related processes in cancer, cardiovascular, and neurodegenerative disease research. Jun 21 2026
E6782 BHV-2100 BHV-2100 is a potent, selective, peripherally restricted, orally administered, first-in-class antagonist of TRPM3 with IC50 between 1–10 nM. It also reduces pain in preclinical models without thermoregulatory or sedative effects. Jun 16 2026
E6525 AMXT-1501 tetrahydrochloride AMXT-1501 tetrahydrochloride is an orally bioavailable polyamine transport inhibitor that works synergistically with DFMO to starve cancer cells, simultaneously blocking their internal polyamine production and external import. In preclinical models, closing both pathways produced strong antitumor activity and signs of restored anti-tumor immune response. Jun 16 2026
E4718 IRG1-IN-1 IRG1-IN-1 is a potent inhibitor of IRG1. Through targeted pharmacologic blockade, it reverses tumor-associated macrophage (TAM)-mediated PARP inhibitor (PARPi) resistance, synergizing with PARPi to suppress tumor growth across multiple immunocompetent models of BRCA1-deficient breast cancer. Jun 16 2026
E4748 EOS-984 EOS-984 (EOS301984) is a potent antagonist of ENT1 that restores pyrimidine levels in activated T cells within adenosine-rich environments. This metabolic rescue enhances tumor cell killing by memory T cells and increases the ex vivo expansion of functional human tumor-infiltrating lymphocytes (TILs). Jun 16 2026
E1454 Phosphoramide mustard cyclohexanamine Phosphoramide mustard cyclohexanamine is the stabilized and biologically active cytotoxic metabolite of the prodrug cyclophosphamide that acts as a potent DNA alkylator. It selectively binds the N-7 position of guanine residues to generate cytotoxic mono- and bi-functional DNA adducts. These cross-links physically stall replication forks and trigger the ATM/gammaH2AX DNA damage response pathway, effectively driving malignant cells into apoptosis. Jun 11 2026
E5884 DNA2 inhibitor C5 DNA2 inhibitor C5 (NSC-15765) is a potent, competitive, and specific DNA2 nuclease inhibitor with an IC50 of 20 μM. By targeting an allosteric pocket near the DNA-binding site, it comprehensively shuts down the multi-catalytic functions of DNA2—effectively suppressing its nuclease, DNA-dependent ATPase, helicase, and direct DNA-binding activities. Jun 10 2026
E4689 Nrf2-IN-1 Nrf2-IN-1 (Compound 4f) is a potent pyrazolyl hydroxamic acid derivative and specific inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2). By downregulating Nrf2 protein levels and blocking the downstream Nrf2-ARE antioxidant signaling pathway, it disrupts cellular redox homeostasis. Jun 10 2026
F3803 Pin1 Antibody (Mouse mAb) [C4H20] Jun 09 2026
F2683 NeuN Antibody (Mouse mAb) [E22E10] Jun 09 2026
F1570 NUP153 Antibody (Mouse mAb) [L18J13] Jun 09 2026
F3389 RBPSUH Antibody (Rabbit mAb) [M13J4] Jun 09 2026
F6608 IL-2 Antibody (Rabbit mAb) [G3L7] Jun 09 2026
F6702 NLK Antibody (Rabbit mAb) [D1D21] Jun 09 2026
F9097 CD163 Antibody (Rabbit mAb) [P6H23] Jun 09 2026
F3641 NEK6 Antibody (Rabbit mAb) [P9K17] Jun 09 2026
F6825 β IV Tubulin Antibody (Mouse mAb) [A2G2] Jun 09 2026
F6483 PKC β Antibody (Rabbit mAb) [C22A12] Jun 09 2026
F7890 NKp46/NCR1 Antibody (Mouse mAb) [K17G8] Jun 09 2026
F9828 BMP-1/PCP Antibody (Rat mAb) [D9N3] Jun 09 2026
F7230 NOX4 Antibody (Rabbit mAb) [M9N20] Jun 09 2026
F8794 CX3CR1 Antibody (Rabbit mAb) [G13H18] Jun 09 2026
F6729 TRAF4 Antibody (Mouse mAb) [N23M6] Jun 09 2026
F3179 DIAPH1 Antibody (Rabbit mAb) [J8A16] Jun 09 2026
F6238 Calponin 1 Antibody (Rabbit mAb) [B15N12] Jun 09 2026
F6080 CXCL2 Antibody (Rabbit mAb) [H18N1] Jun 09 2026
F4630 NY-ESO-1 Antibody (Rabbit mAb) [D2K7] Jun 09 2026
F5972 AP-2α Antibody (Rabbit mAb) [H2P15] Jun 09 2026
F2913 COX6B1 Antibody (Rabbit mAb) [J13A19] Jun 09 2026
F3671 MST3 Antibody (Rabbit mAb) [F21L14] Jun 09 2026
F4915 MRP1/ABCC1 Antibody (Rabbit mAb) [M22C19] Jun 09 2026
F4937 MEKK1 Antibody (Mouse mAb) [B14N1] Jun 09 2026
F6871 RIF1 Antibody (Rabbit mAb) [L2M1] Jun 09 2026
F4934 Ribosomal Protein S7 Antibody (Mouse mAb) [E20M7] Jun 09 2026
F5574 Aggrecan Antibody (Rabbit mAb) [M12J8] Jun 09 2026
F4505 SmarcAL1 Antibody (Mouse mAb) [K9N14] Jun 09 2026
F4489 Gαi-1/GNAI1 Antibody (Mouse mAb) [B24D21] Jun 09 2026
F4491 FZR1 Antibody (Mouse mAb) [E11J24] Jun 09 2026
F2207 Osteopontin Antibody (Rabbit mAb) [K22J24] Jun 09 2026
F4710 FKBP5 Antibody (Rabbit mAb) [J11H16] Jun 09 2026
F8638 NM23A Antibody (Rabbit mAb) [E3D15] Jun 09 2026
F9368 PSMC2 Antibody (Mouse mAb) [A15H16] Jun 09 2026
F7665 CDK12 Antibody (Rabbit mAb) [N24C20] Jun 09 2026
F5249 GCN1 Antibody (Rabbit mAb) [G16A4] Jun 09 2026
F8354 N myc interactor/NMI Antibody (Rabbit mAb) [B12H19] Jun 09 2026
F7762 MafA Antibody (Rabbit mAb) [N21K22] Jun 09 2026
F6897 OGDH Antibody (Rabbit mAb) [L20G5] Jun 09 2026
F4204 CDC42 Antibody (Rabbit mAb) [B14M24] Jun 09 2026
F4261 NEDD4-L Antibody (Mouse mAb) [P22P8] Jun 09 2026
F3302 FMNL2 Antibody (Mouse mAb) [A6K4] Jun 09 2026
F6803 YKL-40/CHI3L1 Antibody (Rabbit mAb) [M13C3] Jun 09 2026
F5605 Myosin IIb Antibody (Rabbit mAb) [F18M11] Jun 09 2026
F7174 NSD3 Antibody (Rabbit mAb) [D12B18] Jun 09 2026
F0518 Phospho-Akt1 (Ser473) Antibody (Rabbit mAb) [E4M2] Jun 09 2026
F1198 Mer Antibody (Rabbit mAb) [C10E14] Jun 09 2026
F4314 MIRAB13 Antibody (Mouse mAb) [F12J3] Jun 09 2026
F5166 NKCC1 Antibody (Rabbit mAb) [A2N20] Jun 09 2026
F4733 β Amyloid (Aβ) 1-42 Antibody (Rabbit mAb) [N17C24] Jun 09 2026
F6082 IFI16 Antibody (Rabbit mAb) [E2M12] Jun 09 2026
F9887 Cdk8 Antibody (Rabbit mAb) [G17E8] Jun 09 2026
F8230 MBNL2 Antibody (Mouse mAb) [H9D23] Jun 09 2026
F7048 Cullin 4B/CUL-4B Antibody (Rabbit mAb) [J23G17] Jun 09 2026
F7344 Swd2 Antibody (Rabbit mAb) [L22F8] Jun 09 2026
F9557 BRE Antibody (Rabbit mAb) [F1N20] Jun 09 2026
F5138 Tubulin β Class V Antibody (Mouse mAb) [P1M16] Jun 09 2026
F8335 NMNAT-1 Antibody (Mouse mAb) [H16N17] Jun 09 2026
F8820 Cytochrome P450 Reductase Antibody (Rabbit mAb) [A13P3] Jun 09 2026
F1107 DLAT Antibody (Rabbit mAb) [L23H19] Jun 09 2026
F8033 DDX6 Antibody (Rabbit mAb) [J2G17] Jun 09 2026
F2889 Perilipin-1 Antibody (Rabbit mAb) [B3G1] Jun 09 2026
F0953 OAS1 Antibody (Rabbit mAb) [N5C17] Jun 09 2026
F4792 SDF-1 Antibody (Rabbit mAb) [M4G11] Jun 09 2026
F3026 COL3A1 Antibody (Rabbit mAb) [P18A14] Jun 09 2026
F4601 Phospho-MLKL (Ser358) Antibody (Rabbit mAb) [K9E15] Jun 09 2026
F4969 Phospho-eIF4G (Ser1108) Antibody (Rabbit mAb) [G15K10] Jun 09 2026
F9999 CXCL13 Antibody (Mouse mAb) [E8F3] Jun 09 2026
F9902 Phospho-DDR1 (Tyr513) Antibody (Rabbit mAb) [F16D7] Jun 09 2026
F5804 Phospho-Cyclin B1 (Ser133) Antibody (Rabbit mAb) [K22L23] Jun 09 2026
F4769 Tachykinin-3 Antibody (Mouse mAb) [K4A12] Jun 09 2026
F6955 Ras (G12D Mutant) Antibody (Rabbit mAb) [C11A12] Jun 09 2026
F7369 PREX1 Antibody (Rabbit mAb) [J20N16] Jun 09 2026
F9077 HGF β Antibody (Rabbit mAb) [F7L16] Jun 09 2026
F6254 PLK2 Antibody (Rabbit mAb) [M21F17] Jun 09 2026
F0597 Phospho-JAK2 (Tyr1007) Antibody (Rabbit mAb) [G9F22] Jun 09 2026
F3822 TGN46 Antibody (Mouse mAb) [H8C2] Jun 09 2026
F8636 Phospho-Estrogen Receptor α (Ser167) Antibody (Rabbit mAb) [D20F17] Jun 09 2026
F9976 Cannabinoid receptor 2 Antibody (Rabbit mAb) [G5B22] Jun 09 2026
F8922 ACE2 Antibody (Rabbit mAb) [P24F5] Jun 09 2026
F6522 Cathepsin L Antibody (Mouse mAb) [E18C8] Jun 09 2026
F5087 GYG1 Antibody (Mouse mAb) [E16D17] Jun 09 2026
F4996 MAFA Antibody (Rabbit mAb) [N15J3] Jun 09 2026
F9678 VEGF Receptor 3 Antibody (Rabbit mAb) [M6F2] Jun 09 2026
F9739 CCL3/MIP-1α Antibody (Rabbit mAb) [C14E20] Jun 09 2026
F9354 USP9X Antibody (Rabbit mAb) [H15M1] Jun 09 2026
F1604 Fast Myosin Skeletal Heavy chain Antibody (Mouse mAb) [A10L9] Jun 09 2026
F9991 IκB-ζ Antibody (Rabbit mAb) [K24D5] Jun 09 2026
F1599 Aggrecan Antibody (Mouse mAb) [D23A4] Jun 09 2026
F9855 Endomucin Antibody (Rabbit mAb) [J13M21] Jun 09 2026
F9404 mCherry Antibody (Rabbit mAb) [P15F10] Jun 09 2026
F8612 mGluR5 Antibody (Rabbit mAb) [D5P24] Jun 09 2026
F5434 HMGCS1 Antibody (Rabbit mAb) [D13C18] Jun 09 2026
F6378 Phospho-ATGL (Ser406) Antibody (Rabbit mAb) [B14A21] Jun 09 2026
F0013 ZO1 tight junction protein Antibody (Rabbit mAb) [C21G5] Jun 09 2026
F5452 LDH-B Antibody (Rabbit mAb) [D9J11] Jun 09 2026
F5602 DBC1 Antibody (Rabbit mAb) [E8N20] Jun 09 2026
F5263 PKMYT1 Antibody (Rabbit mAb) [E20E14] Jun 09 2026
F1613 Endothelin 1 Antibody (Mouse mAb) [F2J1] Jun 09 2026
F2200 Phospho-RSK1 p90 (Thr573) Antibody (Rabbit mAb) [L22G7] Jun 09 2026
F4394 α Cardiac Actin Antibody (Mouse mAb) [J1E19] Jun 09 2026
F4870 Phospho-PLK1 (Thr210) Antibody (Rabbit mAb) [K10L6] Jun 09 2026
F4978 SLC2A9 Antibody (Mouse mAb) [D8G2] Jun 09 2026
F5135 RPL3 Antibody (Mouse mAb) [H7C5] Jun 09 2026
F0991 DMT1/SLC11A2 Antibody (Mouse mAb) [G3J24] Jun 09 2026
F3510 Phospho-Tyrosine Antibody (Mouse mAb) [N16H13] Jun 09 2026
F4382 Neurofilament-M/H Antibody (Mouse mAb) [G10L12] Jun 09 2026
F2251 Rad50 Antibody (Mouse mAb) [P20A20] Jun 09 2026
F4529 AHA1 Antibody (Rat mAb) [L18K15] Jun 09 2026
F4557 Hepatic Sinusoidal Endothelial Cell Antibody (Mouse mAb) [L23C8] Jun 09 2026
F4806 APC8 Antibody (Rabbit mAb) [E8M5] Jun 09 2026
F4841 Peroxiredoxin 1/PAG Antibody (Rabbit mAb) [N9K11] Jun 09 2026
F4946 NUP98 (Nuclear Pore Marker) Antibody (Rat mAb) [L2D21] Jun 09 2026
F4950 GOLPH3 Antibody (Mouse mAb) [L14M1] Jun 09 2026
F5130 EEF1D Antibody (Mouse mAb) [G11C24] Jun 09 2026
F1546 TMEM119 (Microglial Marker) Antibody (Rabbit mAb) [H12P23] Jun 09 2026
F4341 Siglec-1/CD169 Antibody (Mouse mAb) [E18B9] Jun 09 2026
F4533 Langerin/CD207 Antibody (Rat mAb) [F3M20] Jun 09 2026
F4837 Phospho-SQSTM1/p62 (Ser349) Antibody (Rabbit mAb) [N16A3] Jun 09 2026
F5109 SDC2 Antibody (Mouse mAb) [D5J9] Jun 09 2026
E6808 PRLX-93936 hydrochloride PRLX-93936 hydrochloride is a potent molecular glue degrader that selectively binds to E3 ubiquitin ligase TRIM21 and forms a functional ternary complex between TRIM21 and NUP98 (Nucleoporin 98). This complex formation drives the subsequent polyubiquitination and proteasomal degradation of NUP98 alongside other essential components of the nuclear pore complex (NPC). Jun 08 2026
E6809 JWZ-8-103 JWZ-8-103 is an orally bioavailable selective degrader of the nuclear pore complex that acts as a TRIM21-targeting molecular glue. It induces a robust TRIM21 PRYSPRY–NUP98 APD interaction with an apparent EC50 ≈ 20 µM and increases TRIM21 thermal stability. It also exhibits potent antitumor efficacy in pancreatic cancer xenografts and patient-derived organoids. Jun 08 2026
E6731 Tacaciclib Tacaciclib (AUR-102, XL-102) is a specific and orally bioavailable covalent inhibitor of CDK7 with an IC50 of 12 nM, 5 nM and 0.9 nM for 20, 60 and 180 min, respectively. It also induces apoptosis in AML cells via CDK7/c-Myc/p53 axis. Jun 08 2026
E6719 IID432 IID432 is a highly efficacious and safe oral cyanotriazole inhibitor of Trypanosoma cruzi topoisomerase II, with an EC50 of 8 nM. It achieved relapse-free (sterile) parasite clearance in wash-out assays and a single 25 mg/kg dose cleared infection in mice. IID432 has potential as a curative, short-course treatment for Chagas disease. Jun 08 2026
E6555 Alogabat Alogabat (RG-7816; RO-7017773) is a positive allosteric modulator (PAM) of the GABAA α5 receptor, with a ki of 7.9 nM for α5β3γ2 subunit. It enhances GABA-evoked responses at α5-containing receptors and shows antiseizure activity without cognitive/sedative impairment at therapeutic doses. Jun 08 2026
S7945 Echinomycin (Quinomycin A) Echinomycin (Quinomycin A;NSC-13502) is a potent, cell‑permeable inhibitor of HIF‑1–mediated gene transcription that bis‑intercalates into DNA in a sequence‑specific manner, thereby blocking HIF‑1α/β binding to hypoxia‑responsive elements and reversibly inhibiting hypoxia‑induced HIF‑1 transcriptional activity in U251‑HRE cells with an EC50 of approximately 1.2 nM. Jun 08 2026
E5937 AK-1690 AK‑1690 is a selective PROTAC degrader of STAT6 (DC50 ≈ 1 nM) that recruits STAT6 to cereblon, inducing its ubiquitin‑dependent proteasomal degradation in cells and tissues. Jun 08 2026
E6691 SIRT4-IN-1 SIRT4-IN-1 (Compound 69) is a potent, cell-permeable small-molecule inhibitor of Sirtuin 4 (Sirt4) with an IC50 of 16 μM against human Sirt4 (hSirt4). It also acts as a competitive inhibitor of acyl peptide substrate, binding directly within the Sirt4 acyl-binding pocket and noncompetitive with the NAD+ cofactor. SIRT4-IN-1 treatment effectively increases glutamate dehydrogenase (GDH) activity and rescues pyruvate dehydrogenase (PDH) activity. Jun 07 2026
E6689 Pociredir Pociredir(FTX-6058) is a potent, orally bioavailable inhibitor of Embryonic Ectoderm Development (EED), a core regulatory subunit of the polycomb repressive complex 2 (PRC2). By disrupting this epigenetic mechanism, the compound downregulates key fetal globin repressors to robustly induce fetal hemoglobin (HbF) protein expression in both cellular and murine models. Jun 07 2026
F2665 Rabbit IgG Isotype Control Antibody (Rabbit mAb) [D24D4] Jun 07 2026
E6510 LOXO-435 Jun 03 2026
E1852 RLY-2608 RLY‑2608 (zovegalisib) is an oral, first‑in‑class allosteric, pan‑mutant‑selective inhibitor of PI3Kα that preferentially targets oncogenic PIK3CA mutants, retaining antitumor activity while reducing PI3Kα‑related metabolic toxicities. Jun 03 2026
E1309 AP39 AP39 is a triphenylphosphonium‑derivatised anethole dithiolethione and a mitochondria‑targeted hydrogen sulfide (H₂S) donor that increases intracellular, particularly mitochondrial, H₂S levels. AP39 also preserves mitochondrial DNA integrity under oxidative stress and protects against myocardial reperfusion injury in mice. Jun 02 2026
E6692 QC6352 QC6352 is a potent, orally active small‑molecule inhibitor of the lysine demethylase 4 (KDM4/JMJD2) family, which increases histone H3K36 trimethylation in cells overexpressing KDM4C. It also exhibits significant antiproliferative and antitumor effects, such as tumor volume reduction in HER2‑positive breast cancer patient‑derived xenograft models. Jun 01 2026
E6755 Z4P Z4P is a blood–brain barrier–penetrant inhibitor of IRE1 with an IC50 of 1.18 μM, which exhibits potential for the adjuvant treatment of glioblastoma. Jun 01 2026
E6645 CellTracker Blue CMAC CellTracker Blue CMAC is a cell-permeant, thiol-reactive blue fluorescent dye used for long-term labeling and tracking of live cells. once inside cells, it is converted to a fluorescent, glutathione-conjugated product that is well retained and passed to daughter cells while remaining non-toxic. It exhibits excitation/emission maxima around 350/460 nm, allowing use in the DAPI channel and leaving green/red channels free for other fluorophores. May 31 2026
E1844 STX-721 STX-721(Elticertinib) is an irreversible inhibitor of EGFR harboring exon 20 insertion (ex20ins) mutations that selectively inhibits the proliferation of Ba/F3 cells expressing EGFR exon20 A769_V770insASV and D770_N771insSVD with an IC50 of 5.4 and 5.8 nM, respectively. May 31 2026
E4625 Incyclinide Incyclinide (CMT-3, COL-3) is a non‑antimicrobial, chemically modified tetracycline (CMT) and an inhibitor of matrix metalloproteinases, including MMP‑13, MMP‑1 and MMP‑8 with an IC50 of 0.3 µg/ml, 34 µg/ml and 48 µg/ml, respectively. May 31 2026
E6752 ADS032 ADS032 is a dual inhibitor of NLRP1 and NLRP3 that directly, rapidly, reversibly and stably inhibits inflammasome formation, reducing NLRP1‑ and NLRP3‑dependent activation in human‑derived macrophages and bronchial epithelial cells, thereby decreasing IL‑1β maturation and secretion, TNF‑α production, and NLRP3‑induced ASC speck formation. May 31 2026
F2577 Von Hippel Lindau/VHL Antibody (Mouse mAb) [A6D6] May 27 2026
F5894 Proteasome 20S β7 Antibody (Mouse mAb) [N12L11] May 27 2026
F7178 MKP-5 Antibody (Mouse mAb) [K14L19] May 27 2026
F7126 PME-1 Antibody (Mouse mAb) [L6L14] May 27 2026
F6179 Stathmin Antibody (Rabbit mAb) [M5B10] May 27 2026
F4311 RGS2 Antibody (Mouse mAb) [A1F17] May 27 2026
F4515 CD109 Antibody (Mouse mAb) [K2B17] May 27 2026
F4930 VPS4B Antibody (Mouse mAb) [C16M22] May 27 2026
F4482 ANP Antibody (Mouse mAb) [M21G12] May 27 2026
F7701 SPIB Antibody (Rabbit mAb) [F10D9] May 27 2026
F9793 PHLDA1 Antibody (Rabbit mAb) [F2D2] May 27 2026
F7430 Lipocalin-2/NGAL Antibody (Rabbit mAb) [N17E16] May 27 2026
F5888 SEC22B Antibody (Rabbit mAb) [P7F4] May 27 2026
F6840 Phospho-eIF4B (Ser406) Antibody (Rabbit mAb) [E13A7] May 27 2026
F9272 Optineurin Antibody (Rabbit mAb) [D24C11] May 27 2026
F8555 BCKDHA Antibody (Rabbit mAb) [K21P5] May 27 2026
F6929 LAG3 Antibody (Rabbit mAb) [J16E22] May 27 2026
F7808 Lck Antibody (Rabbit mAb) [P2J8] May 27 2026
F8332 SNX3 Antibody (Rabbit mAb) [J24C14] May 27 2026
F5870 SPARC Antibody (Rabbit mAb) [A10J5] May 27 2026
F8235 SARM1 Antibody (Rabbit mAb) [H21M23] May 27 2026
F7457 Gα(q) Antibody (Rabbit mAb) [C11L2] May 27 2026
F5970 Phospho-MEK1 (Thr286) Antibody (Rabbit mAb) [K15K24] May 27 2026
F8897 PELP1 Antibody (Rabbit mAb) [M14C23] May 27 2026
F3817 C5 Antibody (Mouse mAb) [J8C4] May 27 2026
F9637 CISD1/MitoNEET Antibody (Rabbit mAb) [M24F17] May 27 2026
F9852 ATAD3A Antibody (Rabbit mAb) [K13L10] May 27 2026
F7856 Spry2 Antibody (Rabbit mAb) [A12L7] May 27 2026
F9538 HLA-DR Antibody (Rabbit mAb) [L16M22] May 27 2026
F8195 Emerin Antibody (Rabbit mAb) [L11H10] May 27 2026
F6454 VAPB Antibody (Rabbit mAb) [L11L13] May 27 2026
F8092 CD105 Antibody (Rabbit mAb) [F19M3] May 27 2026
F6113 SSRP1 Antibody (Mouse mAb) [H15L10] May 27 2026
F5394 DAB2 Antibody (Rabbit mAb) [K17C17] May 27 2026
F8666 MICB Antibody (Rabbit mAb) [C17D9] May 27 2026
F7629 APE Antibody (Rabbit mAb) [F3K5] May 27 2026
F3449 Phospho-Twist (Ser68) Antibody (Rabbit mAb) [M15K16] May 27 2026
F2187 Endomucin Antibody (Rat mAb) [L6H14] May 27 2026
F2241 Histone H3 (di/tri methyl K4) Antibody (Mouse mAb) [A19H7] May 27 2026
F3174 Strep-tag II Antibody (Rabbit mAb) [C20H20] May 27 2026
F2713 Phospho-PERK (Thr980) Antibody (Rabbit mAb) [E9N5] May 27 2026
F1539 pro Caspase-1+p10+p12 Antibody (Rabbit mAb) [H3L1] May 27 2026
F2811 Pyrin Antibody (Rabbit mAb) [L17B15] May 27 2026
F3738 CENPF Antibody (Rabbit mAb) [G20B19] May 27 2026
F3635 NAPSIN A Antibody (Rabbit mAb) [P4L17] May 27 2026
F3466 Renilla Luciferase Antibody (Rabbit mAb) [G15A23] May 27 2026
F3926 Somatostatin Antibody (Mouse mAb) [J16B12] May 27 2026
F3973 Phospho-BTK (Tyr551) Antibody (Rabbit mAb) [D4E1] May 27 2026
F4080 FLT3 Antibody (Rabbit mAb) [H6L24] May 27 2026
F4160 SARS-CoV-2 Spike Protein (S1) Antibody (Rabbit mAb) [N11L5] May 27 2026
F3991 SCXA Antibody (Rabbit mAb) [M20P22] May 27 2026
F3343 Phospho-Tuberin/TSC2 (Thr1462) Antibody (Rabbit mAb) [F15L14] May 27 2026
F4816 MX1 Antibody (Rabbit mAb) [C7P8] May 27 2026
F4388 UTF-1 Antibody (Mouse mAb) [B24H16] May 27 2026
F4571 TLR4 Antibody (Mouse mAb) [L6M8] May 27 2026
F4612 Akt3 Antibody (Rabbit mAb) [C10D18] May 27 2026
F4680 BNIP3 Antibody (Rabbit mAb) [A22K11] May 27 2026
F3814 SREBP-2 Antibody (Mouse mAb) [J5M10] May 27 2026
F4506 HHV-8 K-bZIP Antibody (Mouse mAb) [B1F14] May 27 2026
F2827 Phospho-Tau (Ser262+Thr263) Antibody (Rabbit mAb) [D14G14] May 27 2026
F3920 Otx1/2 Antibody (Rabbit mAb) [M1P17] May 27 2026
F4876 MyoD1 Antibody (Rabbit mAb) [M18A7] May 27 2026
F3030 IRF-7 Antibody (Rabbit mAb) [C15N21] May 27 2026
F0979 Brachyury/Bry Antibody (Rabbit mAb) [B3G11] May 27 2026
F4764 Gasdermin D Antibody (Rabbit mAb) [B17C12] May 27 2026
F4902 Rubella Virus capsid Antibody (Mouse mAb) [M17H6] May 27 2026
F4135 Akt1 Antibody (Rabbit mAb) [B17F18] May 27 2026
F9904 Phospho-JunB (Thr102/Thr104) Antibody (Rabbit mAb) [A14M16] May 27 2026
F2230 Myosin light chain kinase/MLCK Antibody (Rabbit mAb) [F16B16] May 27 2026
F5009 MSH6 Antibody (Rabbit mAb) [J6H14] May 27 2026
F4639 FGF Receptor 2 Antibody (Rabbit mAb) [J1D10] May 27 2026
F7013 SAT1 Antibody (Rabbit mAb) [F2F22] May 27 2026
F8677 Mast Cell Chymase Antibody (Rabbit mAb) [C20M13] May 27 2026
F5040 Phospho-RPA32/RPA2 (Ser33) Antibody (Rabbit mAb) [H16F6] May 27 2026
F5034 GABARAPL2/GATE-16 Antibody (Rabbit mAb) [J14F14] May 27 2026
F3460 RSK4 Antibody (Rabbit mAb) [K23J12] May 27 2026
F0064 VEGFA C-terminal Antibody (Rabbit mAb) [D1C9] May 27 2026
F5140 Cellubrevin Antibody (Rabbit mAb) [C19C14] May 27 2026
F7073 Phospho-Sin1 (Thr86) Antibody (Rabbit mAb) [L3G17] May 27 2026
F7101 Phospho-Vimentin (Ser56) Antibody (Rabbit mAb) [M10H3] May 27 2026
F7388 CRBN Antibody (Rabbit mAb) [M9N10] May 27 2026
F6672 Phospho-c-Myc (Thr58) Antibody (Rabbit mAb) [G15N9] May 27 2026
F9784 ABCA1 Antibody (Rabbit mAb) [E4K4] May 27 2026
F7106 Reg3B Antibody (Rat mAb) [C3N11] May 27 2026
F8294 Virilizer Antibody (Rabbit mAb) [D21H17] May 27 2026
F5992 VEGF165b Antibody (Mouse mAb) [B10E21] May 27 2026
F8410 SEC61A Antibody (Rabbit mAb) [G23E7] May 27 2026
F9581 PKCι/λ Antibody (Mouse mAb) [H1H7] May 27 2026
F4785 IL-1β Antibody (Rabbit mAb) [N17M3] May 27 2026
F5067 A1/Bfl-1 Antibody (Rabbit mAb) [N2F22] May 27 2026
F9187 CHMP4B Antibody (Rabbit mAb) [P12D13] May 27 2026
F9208 IGFBP3 Antibody (Rabbit mAb) [G15L3] May 27 2026
F6371 IFN-γ Antibody (Rabbit mAb) [A12D6] May 27 2026
F7351 Phospho-PLCβ3 (Ser537) Antibody (Rabbit mAb) [K10E11] May 27 2026
F7318 p57 Kip2 Antibody (Mouse mAb) [B21E12] May 27 2026
F8837 COL4A2 Antibody (Rabbit mAb) [K16J16] May 27 2026
F8706 NK-1R Antibody (Rabbit mAb) [A17A4] May 27 2026
F4056 REST Antibody (Mouse mAb) [B2F15] May 27 2026
F2723 Phospho-4E-BP1 (Thr37) Antibody (Rabbit mAb) [L9H8] May 27 2026
F6534 Puromycin Antibody (Rabbit mAb) [H12G14] May 27 2026
F9610 PTPN14 Antibody (Rabbit mAb) [H23F7] May 27 2026
F6543 PREX1 Antibody (Rabbit mAb) [B1D11] May 27 2026
F9694 SNAT1/SLC38A1 Antibody (Rabbit mAb) [G3B8] May 27 2026
F6560 CLCN3 Antibody (Rabbit mAb) [E24D24] May 27 2026
F8526 RAB7B Antibody (Rabbit mAb) [K12N3] May 27 2026
F7289 IL-18 Antibody (Rabbit mAb) [D17G22] May 27 2026
F8360 IL-18 Antibody (Rabbit mAb) [D7E17] May 27 2026
F8891 Tenascin C Antibody (Rabbit mAb) [L15L8] May 27 2026
F6295 Rad50 Antibody (Rabbit mAb) [C10K20] May 27 2026
F7291 Bub1 Antibody (Rabbit mAb) [D12M3] May 27 2026
F5976 Syntaxin1A Antibody (Mouse mAb) [L16C23] May 27 2026
F7469 Syntaxin1A Antibody (Mouse mAb) [B3L13] May 27 2026
F5526 NK1R Antibody (Mouse mAb) [J8D24] May 27 2026
F5006 CRTC3 Antibody (Rabbit mAb) [M6H14] May 27 2026
F6973 MLK1 Antibody (Rabbit mAb) [M13M22] May 27 2026
F5043 MEKK3 Antibody (Rabbit mAb) [G24J6] May 27 2026
F6527 REPS1 Antibody (Rabbit mAb) [L1K3] May 27 2026
F6076 Glutathione Peroxidase 4 Antibody (Rabbit mAb) [P24F22] May 27 2026
F9030 BDNF Antibody (Rabbit mAb) [A7P4] May 27 2026
F5641 NeuroD1 Antibody (Rabbit mAb) [L10E15] May 27 2026
F9672 SATB2 Antibody (Rabbit mAb) [C16D1] May 27 2026
F7141 EphB2 Antibody (Rabbit mAb) [D9P3] May 27 2026
F5479 HRPT2/Parafibromin Antibody (Rabbit mAb) [E14N24] May 27 2026
F5855 Human κ Chain Antibody (Rabbit mAb) [B9H19] May 27 2026
F7835 SNAP25 Antibody (Rabbit mAb) [P1D7] May 27 2026
F5960 CRMP2 Antibody (Rabbit mAb) [K16M14] May 27 2026
A3177 Inbakicept May 26 2026
A3180 Evorpacept May 26 2026
A3181 Socazolimab May 26 2026
E4699 Soquelitinib Soquelitinib (CPI‑818) is an orally active and selective covalent (irreversible) inhibitor of interleukin‑2‑inducible T‑cell kinase (ITK). It modulates tumor immunity by reducing the expression of T‑cell exhaustion markers and can restore effector function in exhausted T cells. May 24 2026
E1851 Succinyl phosphonate trisodium salt Succinyl phosphonate trisodium salt, a trisodium salt of succinyl phosphonate, is a selective inhibitor of the α‑ketoglutarate dehydrogenase complex (KGDHC). By reducing KGDHC activity and succinyl‑CoA–dependent protein succinylation, it modulates mitochondrial metabolism and protects neurons from glutamate‑ and β‑amyloid‑induced injury. May 24 2026
E4761 Osivelotor Osivelotor (GBT‑601; GBT‑021601) is an orally effective small‑molecule allosteric modulator of deoxyhemoglobin S (HbS). It inhibits HbS polymerization and prevents erythrocyte sickling, and exhibits the potential to be used in the treatment and study of sickle cell disease (SCD). May 24 2026
E6803 TRI-611 TRI‑611 is a potent, brain‑penetrant molecular glue degrader of ALK fusion proteins that recruits CRBN to a distal degron, promoting polyubiquitination and degradation of wild‑type and TKI‑refractory ALK, and inducing tumor regressions in ALK‑positive NSCLC models. May 21 2026
E6583 Atpenin A5 Atpenin A5 is a potent and specific mitochondrial complex II inhibitor with an IC50 of ~10 nM. It also acts as an mKATP channel agonist and confers cardioprotection in models of ischemia–reperfusion injury. May 21 2026
E6833 Glyphosate Glyphosate is a non‑selective, systemic broad‑spectrum herbicide and a phosphonomethyl derivative of the amino acid glycine. It inhibits the enzyme 5‑enolpyruvylshikimate‑3‑phosphate synthase (EPSPS) in the shikimate pathway, thereby blocking synthesis of the aromatic amino acids phenylalanine, tyrosine, and tryptophan. May 21 2026
F6860 Ezrin Antibody (Mouse mAb) [L20P21] May 19 2026
F9697 TRAF5 Antibody (Rabbit mAb) [C3D23] May 19 2026
F3474 Cubilin C-terminal Antibody (Rabbit mAb) [C16H20] May 19 2026
F4893 HSF1 Antibody (Rabbit mAb) [H19A5] May 19 2026
F4797 TFEB Antibody (Rabbit mAb) [G16A13] May 19 2026
F7041 Fragilis Antibody (Rabbit mAb) [E3D3] May 19 2026
F5116 NAPRT1 Antibody (Mouse mAb) [H9L14] May 19 2026
F2980 Ferritin Light Chain Antibody (Rabbit mAb) [N3B24] May 19 2026
F5148 HuD Antibody (Rabbit mAb) [M19B4] May 19 2026
F7739 Calponin 3 Antibody (Rabbit mAb) [N11H14] May 19 2026
F2941 UCH37 Antibody (Rabbit mAb) [P22L1] May 19 2026
F8319 Mer Antibody (Rabbit mAb) [M17J16] May 19 2026
F4663 Estrogen Related Receptorα Antibody (Rabbit mAb) [H18K23] May 19 2026
F6623 PRMT6 Antibody (Rabbit mAb) [K2N19] May 19 2026
F4709 CAB39/MO25 Antibody (Rabbit mAb) [H1E9] May 19 2026
F9066 ATPIF1 Antibody (Mouse mAb) [L4C2] May 19 2026
F5477 RPL11 Antibody (Mouse mAb) [K10D6] May 19 2026
F8609 Ceruloplasmin Antibody (Mouse mAb) [K22D1] May 19 2026
F4856 Cyclin T1 Antibody (Rabbit mAb) [L16J22] May 19 2026
F8283 TAB2 Antibody (Rabbit mAb) [E6J10] May 19 2026
F4815 CD19 Antibody (Rabbit mAb) [H7K12] May 19 2026
F2740 TRAP1 Antibody (Mouse mAb) [H11J13] May 19 2026
F6195 PHB2 Antibody (Rabbit mAb) [P5A22] May 19 2026
F4906 ITK Antibody (Rabbit mAb) [H23L5] May 19 2026
F6834 SHMT2/SHMT Antibody (Rabbit mAb) [H9N23] May 19 2026
F7263 14-3-3 eta/YWHAH Antibody (Rabbit mAb) [H13P22] May 19 2026
F8168 HDAC7 Antibody (Rabbit mAb) [P6D17] May 19 2026
F1409 Phospho-EGF Receptor (Tyr998) Antibody (Rabbit mAb) [L7A22] May 19 2026
F4853 JMJD2A Antibody (Rabbit mAb) [G6B24] May 19 2026
F7767 SHIP2 Antibody (Rabbit mAb) [D4N9] May 19 2026
F9725 RCC1 Antibody (Rabbit mAb) [J20J20] May 19 2026
F7079 IL-2Rβ/p75 Antibody (Rabbit mAb) [D16J3] May 19 2026
F9881 C Reactive Protein Antibody (Rabbit mAb) [N20E9] May 19 2026
F4313 β-1,4-Gal-T1 Antibody (Mouse mAb) [C2J8] May 19 2026
F4513 SR-2A Antibody (Mouse mAb) [L13G15] May 19 2026
F8277 PRMT7 Antibody (Rabbit mAb) [F2F1] May 19 2026
F5640 SIRPα/SHPS1 Antibody (Rabbit mAb) [B15C11] May 19 2026
F8393 Fibulin 3 Antibody (Rabbit mAb) [G19N6] May 19 2026
F2409 CaMKIIδ Antibody (Rabbit mAb) [E8P2] May 19 2026
F4590 TREM2 Antibody (Rabbit mAb) [F18K20] May 19 2026
F4905 p95/NBS1 Antibody (Rabbit mAb) [P16D23] May 19 2026
F5070 DMT1/SLC11A2 Antibody (Rabbit mAb) [C16J1] May 19 2026
F9646 DDX3 Antibody (Rabbit mAb) [J24G2] May 19 2026
F9196 RED1 Antibody (Rabbit mAb) [L7J8] May 19 2026
F5494 Serine racemase Antibody (Mouse mAb) [A1N23] May 19 2026
F5758 FGF-23 Antibody (Rat mAb) [B12L4] May 19 2026
F5011 RALA Antibody (Rabbit mAb) [G17M6] May 19 2026
F5023 Phospho-SLP-76 (Ser376) Antibody (Rabbit mAb) [D2F12] May 19 2026
F5024 MAVS Antibody (Rabbit mAb) [H8N11] May 19 2026
F4528 Phospho-RPA32/RPA2 (Ser4/8) Antibody (Rabbit mAb) [M17K6] May 19 2026
F4952 ESRRB Antibody (Mouse mAb) [H9C3] May 19 2026
E6757 BBO-11818 BBO‑11818 is an orally active and non‑covalent inhibitor of pan‑KRAS that binds both the active (GTP‑bound, “ON”) and inactive (GDP‑bound, “OFF”) forms of multiple oncogenic KRAS mutants, including KRAS G12D and G12V. It potently suppresses MAPK signaling and viability in KRAS‑driven cell lines, induces tumor regressions in KRAS‑mutant xenograft models. May 19 2026
E0875 S26131 S26131 (compound 5) is a potent, selective MT1 melatoninergic ligand that behaves as an antagonist at both MT1 and MT2 receptors, with Ki of 0.5 and 112 nM for MT1 and MT2, respectively. May 19 2026
E6710 MKP10241 MKP10241 is a potent, orally active agonist of GPR119 that elevates cAMP levels in a GPR119‑expressing cell line with an EC50 ≈ 3.7 nM. MKP10241 reduces blood glucose and HbA1c in acute and chronic diabetic mouse models and shows excellent preclinical efficacy in rodent models of obesity and MASH. May 19 2026
F1642 SV40 T-antigen Antibody (Mouse mAb) [C12F2] May 19 2026
F2749 HSD3B2 Antibody (Mouse mAb) [J9K21] May 19 2026
F1126 CTGF Antibody (Rabbit mAb) [P10H5] May 19 2026
F2916 Syntaxin Antibody (Mouse mAb) [K5F22] May 19 2026
F0972 Toll-like Receptor 9 Antibody (Mouse mAb) [K21F2] May 19 2026
F3843 BMP7 Antibody (Rabbit mAb) [J15D7] May 19 2026
F5129 ECHS1 Antibody (Mouse mAb) [N10G4] May 19 2026
F6753 Flightless I Antibody (Rabbit mAb) [N3K8] May 19 2026
F4911 Mad2L1 Antibody (Mouse mAb) [L3N17] May 19 2026
F6715 MLX Antibody (Rabbit mAb) [N17K22] May 19 2026
F0798 Phospho-Elk-1 (Ser383) Antibody (Mouse mAb) [P22B17] May 19 2026
F8764 53BP1 Antibody (Rabbit mAb) [E7B6] May 19 2026
F8879 Phospho-GEF-H1 (Ser886) Antibody (Rabbit mAb) [E24J19] May 19 2026
F6628 GOPC Antibody (Rabbit mAb) [D5A8] May 19 2026
F6681 INPP4B Antibody (Rabbit mAb) [H1L5] May 19 2026
F5176 Tau Antibody (Rabbit mAb) [G23J10] May 19 2026
F2214 Fibroblast Activation Protein α Antibody (Rabbit mAb) [A9L24] May 19 2026
F3385 IRS-1+IRS-2 Antibody (Rabbit mAb) [P5F13] May 19 2026
F0807 Phospho-ABL1 (Tyr245) Antibody (Rabbit mAb) [F15J16] May 19 2026
F7385 SIN3A Antibody (Rabbit mAb) [B10N4] May 19 2026
F8928 Arp3 Antibody (Mouse mAb) [N13C13] May 19 2026
F9211 IDH2 Antibody (Rabbit mAb) [P11N22] May 19 2026
F5456 hnRNP A2B1 Antibody (Rabbit mAb) [A10M11] May 19 2026
F8459 SCG10/Stathmin-2 Antibody (Rabbit mAb) [F16M4] May 19 2026
F4982 ANP32A Antibody (Mouse mAb) [D12M13] May 19 2026
F6852 SAM68 Antibody (Rabbit mAb) [E2F14] May 19 2026
F7071 SMC3 Antibody (Rabbit mAb) [D14N5] May 19 2026
F5041 MRP4/ABCC4 Antibody (Rabbit mAb) [E23K18] May 19 2026
F7704 ALDH1A3 Antibody (Rabbit mAb) [J5E20] May 19 2026
F8862 FGF-19 Antibody (Mouse mAb) [L9N16] May 19 2026
F8212 HLA-G Antibody (Rabbit mAb) [K12D7] May 19 2026
F7338 Phosphoribosyl Pyrophosphate Amidotransferase Antibody (Mouse mAb) [M15J4] May 19 2026
F7894 CNOT7 Antibody (Rabbit mAb) [N8J19] May 19 2026
F6171 Munc18-1 Antibody (Rabbit mAb) [G23A10] May 19 2026
F9875 NRBF2 Antibody (Rabbit mAb) [E16A8] May 19 2026
F7654 ALDH2 Antibody (Mouse mAb) [C21F15] May 19 2026
F1298 Phospho-Insulin Receptor β (Tyr1345) Antibody (Rabbit mAb) [L11H12] May 19 2026
F7166 OTUB1 Antibody (Rabbit mAb) [N21M4] May 19 2026
F2475 GBA Antibody (Mouse mAb) [K1P17] May 19 2026
F5912 PZR Antibody (Rabbit mAb) [F15F10] May 19 2026
F6710 cIAP Pan-specific Antibody (Mouse mAb) [B1J9] May 19 2026
F9281 Cytochrome C Oxidase subunit VIc/COX6C Antibody (Mouse mAb) [C2A20] May 19 2026
F3704 CXCL5 + CXCL6 Antibody (Rabbit mAb) [P8L5] May 19 2026
F9496 Na Channel β1 Subunit Antibody (Rabbit mAb) [F4D21] May 19 2026
F5118 PFN2 Antibody (Mouse mAb) [A7F23] May 19 2026
F5209 PDE4B Antibody (Rabbit mAb) [A23H17] May 19 2026
F7934 TIM 1 Antibody (Rabbit mAb) [M14A22] May 19 2026
F5386 HSP47 Antibody (Rabbit mAb) [D19M10] May 19 2026
F5659 MCT4/SLC16A3 Antibody (Rabbit mAb) [D23C24] May 19 2026
F8272 DAP12 Antibody (Rabbit mAb) [E15J7] May 19 2026
F7769 HLA E Antibody (Mouse mAb) [G19G18] May 19 2026
F2902 Phospho-HER2/ErbB2 (Tyr1139) Antibody (Rabbit mAb) [L15E14] May 19 2026
F6890 TDRD3 Antibody (Rabbit mAb) [C20J18] May 19 2026
F4739 HDAC5 Antibody (Mouse mAb) [B2J1] May 19 2026
F5561 SELS Antibody (Mouse mAb) [N9D15] May 19 2026
E5828 GSK205 GSK205 is a potent and selective antagonist of TRPV4 with an IC50 of 4.19 μM for inhibiting TRPV4‑mediated Ca²⁺ influx. May 18 2026
E6741 SB-405483 SB‑405483 is an allosteric cereblon (CRBN) ligand that cooperatively enhances the binding of orthosteric CRBN ligands (IMiDs) and potentiates degradation of CRBN neosubstrates, including CK1α, Wee1, and IKZF1/3. SB‑405483 stabilizes CRBN and reduces its autoubiquitination. May 18 2026
E6616 CT-179 CT‑179 is a brain‑penetrant, orally bioavailable inhibitor of OLIG2, which exhibits an IC50 of 1.25 μM for human OLIG2. It disrupts OLIG2 dimerization, phosphorylation, and DNA binding and alters tumor cell‑cycle kinetics, increasing differentiation and apoptosis. CT‑179 also prolongs survival in SHH‑MB PDX and GEM models and potentiates the effects of radiotherapy (RT) in vivo. May 17 2026
L2060 Customize Library（compound antibody kit） May 13 2026
E0859 Aminoxyacetic acid Aminoxyacetic acid (AOAA) is an inhibitor of malate–aspartate shuttle (MAS) that effectively suppresses MAS activity in cells. It also induces both early‑ and late‑stage apoptosis of resting and LPS‑activated microglia and impairs their energy metabolism. May 12 2026
E6553 BMS-986463 BMS-986463, a CRBN E3 ligase modulator (CELMoD), is a WEE1 kinase molecular glue degrader that significantly inhibits tumor growth and reduces phospho‑CDK2 levels in preclinical models. May 12 2026
E6771 Bretisilocin Bretisilocin (GM‑2505) is an agonist of 5‑HT2A receptor and 5‑HT releaser that is under development for the treatment of major depressive disorder (MDD). May 12 2026
E6677 CATPB CATPB is an antagonist of FFA2R that inhibits the transient rise in intracellular Ca²⁺ induced in neutrophils by acetate or the synthetic FFAR2 agonist Cmp1, thereby blocking downstream FFAR2‑dependent activation responses, including NADPH oxidase–derived superoxide production. May 12 2026
E6745 Igermetostat Igermetostat (XNW5004) is potent and selective, substrate‑competitive inhibitor of EZH2 that effectively targets both wild‑type and mutant EZH2, leading to marked reduction of H3K27me3, G1/S cell‑cycle arrest, and apoptosis in tumor cells. May 10 2026
E0862 Leucylleucine methyl ester Leucylleucine methyl ester is a lysosomotropic dipeptide that is taken up into leukocyte lysosomes via a dipeptide‑specific transport system and cleaved by the granule enzyme dipeptidyl peptidase I (cathepsin C) into hydrophobic oligomers, which disrupt intracellular membranes and selectively kill cytotoxic lymphocytes and other DPPI‑high cells, with species‑dependent sensitivity of B cells (murine B cells sensitive, human B cells largely resistant). May 10 2026
E6695 3α-Aminocholestane 3-α-aminocholestane is a selective inhibitor of enzymatic activity of INPP5D (SHIP1), an enzyme with a role in controlling immune regulatory cell numbers in vivo, with an IC50 of ~2.5 μmol/l. May 08 2026
E6516 L-Glutamine-13C5 L-Glutamine-13C5 is a stable isotope-labeled form of the non-essential amino acid L-glutamine, where all five carbon atoms are replaced with the isotope^13C. It is primarily used as a tracer in mass spectrometry (LC-MS, GC-MS) or NMR for investigating metabolic pathways, protein synthesis, and cellular nutrient utilization, particularly in cancer research. May 08 2026
E6462 IAMA-6 IAMA‑6 (ARN23746) is a potent, selective, and orally bioavailable inhibitor of the NKCC1 cotransporter. It exhibits the potential to be primarily used in research to treat cognitive impairment in Down syndrome and autism by regulating intracellular chloride homeostasis. May 07 2026
E6718 Polfurmetinib Polfurmetinib(MEK-IN-6,PF-07799544,ARRY-134) (compound 69) is a potent and selective inhibitor of MEK that potently suppresses ERK1/2 phosphorylation at Thr202/Tyr204 in A375 melanoma cells with an IC50 of 2 nM. May 06 2026
E6737 flizasertib flizasertib (GDC-8264) is orally active, reversible, and selective inhibitor of receptor-interacting protein kinase 1 (RIP1), exhibiting Ki app values of 0.00071 μM against human RIP1 and 0.0013 μM against cynomolgus monkey RIP1. May 06 2026
E6733 Adrixetinib TFA Adrixetinib TFA(Q702 TFA) is an orally active, selective triple kinase inhibitor of CSF1R, Mer, and Axl receptors within the TAM (Tyro3/Axl/Mer), exhibiting Kd of 8.7 nM (CSF1R), 0.8 nM (Mer), and 0.3 nM (Axl). It also binds the ATP-binding pockets of these RTKs to block ligand-induced autophosphorylation, disrupting downstream PI3K/Akt and Gas6-mediated survival signaling while repolarizing tumor-associated macrophages from pro-tumorigenic M2 to anti-tumor M1 phenotypes. May 06 2026
E6732 Mesutoclax Mesutoclax (ICP-248) (Compound 5) is a potent, orally bioavailable, and selective inhibitor of BCL-2 with an IC50 of 1.54 nM demonstrating weak activity against BCL-XL with an IC50 > 1000 nM. May 05 2026
E5965 BMS-986458 BMS-986458 is a potent, highly selective, orally bioavailable CRL4 CRBN E3 ubiquitin ligase-dependent BCL6 ligand directed degrader, which exhibits the potential to treat B-cell non-Hodgkin Lymphoma. May 05 2026
E6729 RGH-857 RGH-857 (compound 51) is an orally active positive allosteric modulator (PAM) of the nicotinic α7 acetylcholine (α7 nACh) receptor with an EC50 of 34 nM for human α7 nAChR and demonstrating exceptional potency and efficacy in preclinical models of cognitive impairment. May 05 2026
E6713 BLU-808(SAR449028) BLU-808 (SAR449028) is a potent and selective inhibitor of wild‑type c‑KIT and potently inhibits c‑KIT–dependent phosphorylation and proliferation. It also exhibits therapeutic benefit to patients suffering from wild‑type c‑KIT–mediated mast cell disorders. Apr 28 2026
E6569 MD-4251 MD‑4251 is an orally active PROTAC degrader of MDM2. It potently degrades MDM2 in RS4;11 cells with a DC50 of 0.2 nM and activates p53. Apr 28 2026
E0865 DFHBI-1T DFHBI‑1T is a membrane‑permeable, non‑toxic fluorogenic probe that acts as a ‘light‑up’ sensor for RNA imaging in live cells. It specifically binds to RNA aptamers such as Broccoli, Spinach, and Spinach2, yielding strong green fluorescence with high signal‑to‑noise ratios. Apr 28 2026
E6494 ATR-258 ATR‑258 (Compound 15) is a specific agonist of GRK‑biased β2‑adrenergic receptor (β2AR) with a pEC50 of 6.87 that increases glucose uptake with low cAMP generation. Apr 27 2026
E6773 Olorofim(F901318) Olorofim (F901318) is a reversible inhibitor of dihydroorotate dehydrogenase (DHODH), an oxidoreductase that catalyzes the fourth step in the de novo synthesis of pyrimidines. It exhibits potential for the treatment of invasive mold infections and thermally dimorphic fungi that are refractory to or resistant to clinically available antifungals. Apr 26 2026
E6776 AP-503 AP‑503 is a selective agonist of GPR133/ADGRD1 with an EC50 of 1.21 nM. It exhibits the potential to be used in research on the prevention of muscle‑related diseases and vestibular dysfunction. Apr 26 2026
E6582 LysoTracker Red(LysoTracker Red DND-99) LysoTracker Red (LysoTracker Red DND-99) is an acidotropic, red-fluorescent probe (Ex/Em 577/590 nm) that selectively stains lysosomes and late endosomes in live cells. As a hydrophobic weak base, it freely diffuses across membranes at neutral pH (~7.4), becomes protonated in acidic compartments (pH 4.5-6.0), and traps via charge retention, preventing efflux for high-contrast imaging. Apr 23 2026
E5849 KT-253 KT-253 (Seldegamadlin) is a potent, selective heterobifunctional MDM2 degrader with a DC50 of 0.4 nM and p53 stabilizer. It also exhibits antitumor activity across p53 wild-type hematologic and solid tumors. Apr 23 2026
E6528 BBT-176 BBT-176 is a first-in-class reversible fourth-generation EGFR TKI with potent activity against osimertinib-resistant mutations with an IC50 of 49 nM (Del19/T790M/C797S), 202 nM (L858R/T790M/C797S), 42 nM (Del19/C797S), and 183 nM (L858R/C797S) in Ba/F3 cells. Apr 21 2026
E6738 BCFTP BCFTP is a potent, orally active, selective positive allosteric modulator (PAM) of human MrgprX1 that enhances endogenous ligand signaling to inhibit spinal C-fibre nociceptive transmission, thereby relieving heat hyperalgesia and spontaneous pain in neuropathic models without itch or tolerance. Apr 21 2026
E6663 DDO-02267 DDO‑02267 is a selective, lysine‑targeting covalent inhibitor of ALKBH5, with an IC50 of 0.49 μM. DDO‑02267 increases m⁶A levels and targets the ALKBH5–AXL signaling axis in AML cells. It exhibits the potential to serve as a chemical probe for investigating the biological function of the mRNA demethylase ALKBH5. Apr 21 2026
A2179 Anti-Mouse CD41-Invivo Apr 20 2026
E1270 Afimetoran( BMS-986256) Afimetoran (BMS-986256) is an orally active and selective antagonist of TLR7/8 that potently inhibits NF-κB activation and reverses TLR7-mediated steroid resistance in pDCs. Apr 19 2026
E0874 Ulotaront hydrochloride Ulotaront hydrochloride (SEP-363856 hydrochloride) is an orally active, CNS-penetrant psychotropic agent that acts as an agonist of the trace amine-associated receptor 1 (TAAR1) and serotonin 5-HT1A receptor. It acts as an antipsychotic and used for the treatment of schizophrenia. Apr 19 2026
E0873 Niacin hydrochloride Niacin hydrochloride (Nicotinic acid; Vitamin B3) is a direct and noncompetitive inhibitor of hepatocyte diacylglycerol acyltransferase–2(DGAT2), a key enzyme for TG synthesis, which results in accelerated intracellular hepatic apo B degradation and the decreased secretion of VLDL and LDL particles. Apr 19 2026
E6631 Oxamic acid Oxamic acid (Oxamate) is a classical inhibitor of lactate dehydrogenase‑A (LDH‑A) that competitively blocks the conversion of pyruvate to lactate. It also induces G2/M arrest and apoptosis, and increases radiosensitivity in nasopharyngeal carcinoma cells. Apr 16 2026
E6711 ACI-19626 ACI‑19626 (TDP‑43‑IN‑2) is a first‑in‑class, small‑molecule PET tracer that specifically binds to pathological TDP‑43 aggregates, which are key drivers of neurodegeneration in diseases such as ALS, FTD, and LATE. Apr 16 2026
F5646 MLANA/MART-1 Antibody (Rabbit mAb) [D21A21] Apr 15 2026
F7400 SOX17 Antibody (Rabbit mAb) [F21M23] Apr 15 2026
F6403 Phospho-Rad17 (Ser645) Antibody (Rabbit mAb) [D14D16] Apr 15 2026
F8643 APC1 Antibody (Rabbit mAb) [C16G2] Apr 15 2026
F8114 CYP1B1 Antibody (Rabbit mAb) [C13E23] Apr 15 2026
F6430 RPA70/RPA1 Antibody (Rabbit mAb) [N23A19] Apr 15 2026
F6358 UQCRFS1/RISP Antibody (Rabbit mAb) [P24M17] Apr 15 2026
F7268 GRIM19 Antibody (Rabbit mAb) [J7L19] Apr 15 2026
F7378 Pax6 Antibody (Rabbit mAb) [H2K10] Apr 15 2026
F0677 Cre Recombinase Antibody (Rabbit mAb) [D11J17] Apr 15 2026
F4845 γTubulin (Centrosome Marker) Antibody (Mouse mAb) [D14G7] Apr 15 2026
F5052 BLNK Antibody (Rabbit mAb) [L16M19] Apr 15 2026
F5066 CD147 Antibody (Rabbit mAb) [D10H20] Apr 15 2026
F5071 IKKα Antibody (Rabbit mAb) [B4D5] Apr 15 2026
F5068 Toll-like Receptor 9 Antibody (Rabbit mAb) [M15F23] Apr 15 2026
F5119 PRMT2 Antibody (Mouse mAb) [G16H19] Apr 15 2026
F5081 eIF4B Antibody (Mouse mAb) [D13A19] Apr 15 2026
F5596 eEF1A Antibody (Rabbit mAb) [P21C20] Apr 15 2026
F5039 c-Rel Antibody (Rabbit mAb) [B22C17] Apr 15 2026
F4973 ZEB2 Antibody (Rabbit mAb) [J21B10] Apr 15 2026
F4914 TBP Antibody (Mouse mAb) [B18N3] Apr 15 2026
F5065 T-bet/TBX21 Antibody (Rabbit mAb) [B10M22] Apr 15 2026
F4391 PSF Antibody (Mouse mAb) [M17A24] Apr 15 2026
F7337 SMC2 Antibody (Rabbit mAb) [P11C8] Apr 15 2026
F6237 TACE Antibody (Rabbit mAb) [A22J10] Apr 15 2026
F7512 OS9 Antibody (Rabbit mAb) [M17H4] Apr 15 2026
F9508 FUNDC1 Antibody (Rabbit mAb) [A14J2] Apr 15 2026
F8457 WDR59 Antibody (Rabbit mAb) [P9B16] Apr 15 2026
F9839 Phospho-Tau (Thr205) Antibody (Rabbit mAb) [J19P9] Apr 15 2026
F7572 MLLT1/ENL Antibody (Rabbit mAb) [N21N24] Apr 15 2026
F7840 NDUFB8 Antibody (Rabbit mAb) [B17H14] Apr 15 2026
F8463 TRIM5α Antibody (Rabbit mAb) [E3H20] Apr 15 2026
F6281 Phospho-Lck (Tyr505) Antibody (Rabbit mAb) [P3K14] Apr 15 2026
F8509 Cytochrome b Antibody (Rabbit mAb) [F15F24] Apr 15 2026
F7381 ABCA7 Antibody (Rabbit mAb) [A11M15] Apr 15 2026
F9941 OGDH Antibody (Rabbit mAb) [F21L21] Apr 15 2026
F7802 GFI1 Antibody (Rabbit mAb) [M16D23] Apr 15 2026
F6554 GFI1b Antibody (Rabbit mAb) [B12K19] Apr 15 2026
F5114 MTA2 Antibody (Mouse mAb) [P2H17] Apr 15 2026
F6714 SPHK2 Antibody (Rabbit mAb) [A21H5] Apr 15 2026
F6626 Legumain Antibody (Rabbit mAb) [N22H22] Apr 15 2026
F7735 SirT4 Antibody (Rabbit mAb) [C24N9] Apr 15 2026
F6883 RBM15 Antibody (Rabbit mAb) [L5G12] Apr 15 2026
F7055 PARG Antibody (Rabbit mAb) [B20B2] Apr 15 2026
F7320 Phospho-CAD (Ser1859) Antibody (Rabbit mAb) [C23K19] Apr 15 2026
F8602 LCP1 Antibody (Rabbit mAb) [P20F21] Apr 15 2026
F6401 Mili Antibody (Rabbit mAb) [K20L16] Apr 15 2026
F7214 α-Parvin Antibody (Rabbit mAb) [P1L24] Apr 15 2026
F8644 RBL1 Antibody (Rabbit mAb) [M18D3] Apr 15 2026
F7848 CXXC5 Antibody (Rabbit mAb) [L11K10] Apr 15 2026
F8647 DHCR24/Seladin-1 Antibody (Rabbit mAb) [L8J15] Apr 15 2026
F7745 SPT6 Antibody (Rabbit mAb) [P6D2] Apr 15 2026
F8255 EphA3/A4/A5 Antibody (Rabbit mAb) [A18J10] Apr 15 2026
F5151 FANCA Antibody (Rabbit mAb) [J21M8] Apr 15 2026
F5584 Phospho-LYN (Y397)/LCK (Y394)/HCK (Y411)/BLK (Y389) Antibody (Rabbit mAb) [G2C4] Apr 15 2026
F9786 Phospho-MOB1 (Thr12) Antibody (Rabbit mAb) [F15P10] Apr 15 2026
F6347 SMRT Antibody (Rabbit mAb) [M7D13] Apr 15 2026
F4132 Src Antibody (Rabbit mAb) [L10F23] Apr 15 2026
F4322 DEC1 Antibody (Mouse mAb) [D7J6] Apr 15 2026
F4373 KRAS Antibody (Mouse mAb) [A18C4] Apr 15 2026
F4399 Phospho-MBP (Thr98) Antibody (Mouse mAb) [A3B1] Apr 15 2026
F4401 Keratin Epithelial Antibody (Mouse mAb) [J4M17] Apr 15 2026
F4676 Nicastrin Antibody (Rabbit mAb) [D2C5] Apr 15 2026
F4527 MTP Antibody (Mouse mAb) [J4K3] Apr 15 2026
F4721 PAR2 Antibody (Rabbit mAb) [J17G12] Apr 15 2026
F5275 MAD2L2 Antibody (Rabbit mAb) [P22A23] Apr 15 2026
F5330 SHOC2 Antibody (Rabbit mAb) [H23M19] Apr 15 2026
F4724 Phospho-α-Synuclein (Ser129) Antibody (Rabbit mAb) [G19P15] Apr 15 2026
F6154 Asymmetric-Methyl-PABP1 (Arg455/460) Antibody (Rabbit mAb) [P20H17] Apr 15 2026
F7391 NUP153 Antibody (Rabbit mAb) [M17C21] Apr 15 2026
F8050 Hsp90β Antibody (Rabbit mAb) [N13J8] Apr 15 2026
F2359 Phospho-GSK3β (Y216)/GSK3α (Y279) Antibody (Rabbit mAb) [F22P22] Apr 15 2026
F8406 CHAF1A Antibody (Rabbit mAb) [G22G1] Apr 15 2026
F6265 Phospho-AP2M1 (Thr156) Antibody (Rabbit mAb) [J20G9] Apr 15 2026
F4079 Fas Antibody (Rabbit mAb) [C6C4] Apr 15 2026
F6119 Abi1 Antibody (Rabbit mAb) [D2H9] Apr 15 2026
F5015 CaMKK2 Antibody (Rabbit mAb) [P19A6] Apr 15 2026
F5035 SIX1 Antibody (Rabbit mAb) [N3M10] Apr 15 2026
F8456 ORC2 Antibody (Rat mAb) [P19N22] Apr 15 2026
F5534 Phospho-RCC1 (Ser11) Antibody (Rabbit mAb) [J7C7] Apr 15 2026
F9583 XPF Antibody (Rabbit mAb) [D21K23] Apr 15 2026
F8070 Phospho-Rpb1 CTD (Ser2/Ser5) Antibody (Rabbit mAb) [C1L6] Apr 15 2026
F8979 Phospho-Merlin (Ser518) Antibody (Rabbit mAb) [P22P10] Apr 15 2026
F8224 FAM134B Antibody (Rabbit mAb) [E7A17] Apr 15 2026
F8798 XAF1 Antibody (Rabbit mAb) [C23J4] Apr 15 2026
F4773 Chd1 Antibody (Rabbit mAb) [E24E7] Apr 15 2026
F4942 Sodium Channel Antibody (Mouse mAb) [P23N9] Apr 15 2026
F6053 DAG Lipase β Antibody (Rabbit mAb) [K18L4] Apr 15 2026
F6799 IL-6Rα/CD126 Antibody (Rabbit mAb) [P8F17] Apr 15 2026
F6381 WAPL Antibody (Rabbit mAb) [B12E23] Apr 15 2026
F8574 LEDGF Antibody (Rabbit mAb) [G7D12] Apr 15 2026
F9651 Phospho-Myosin IIa (Ser1943) Antibody (Rabbit mAb) [H18C12] Apr 15 2026
F8556 MERIT40 Antibody (Rabbit mAb) [B22L22] Apr 15 2026
F6346 Phospho-MEK1 (Thr292) Antibody (Rabbit mAb) [F18G17] Apr 15 2026
F7069 Phospho-MCM2 (Ser139) Antibody (Rabbit mAb) [D19G1] Apr 15 2026
F8573 Sec31A Antibody (Rabbit mAb) [J15M23] Apr 15 2026
F9375 ELL Antibody (Rabbit mAb) [B15J21] Apr 15 2026
F7085 Olig2 Antibody (Rabbit mAb) [C6H24] Apr 15 2026
F7845 RRM2 Antibody (Rabbit mAb) [L9E5] Apr 15 2026
F5314 Securin Antibody (Rabbit mAb) [E2P20] Apr 15 2026
F5208 Phospho-NMDA Receptor 2B/GluN2B (Ser1303) Antibody (Rabbit mAb) [F24J19] Apr 15 2026
F8982 DUSP6/MKP3 Antibody (Rabbit mAb) [E9K23] Apr 15 2026
F5399 Phospho-eIF4E (Ser209) Antibody (Rabbit mAb) [G23F17] Apr 15 2026
F6511 Elk-1 Antibody (Rabbit mAb) [J24L11] Apr 15 2026
F5914 Claudin-5 Antibody (Rabbit mAb) [F16P13] Apr 15 2026
F8411 YY1 Antibody (Rabbit mAb) [M11B11] Apr 15 2026
F5231 FTO Antibody (Rabbit mAb) [P22L4] Apr 15 2026
F9219 NPC1 Antibody (Rabbit mAb) [P4H6] Apr 15 2026
F8500 WTAP Antibody (Rabbit mAb) [E21M11] Apr 15 2026
F6946 Lysozyme C Antibody (Rabbit mAb) [J12N14] Apr 15 2026
F7924 Fascin Antibody (Mouse mAb) [K2B22] Apr 15 2026
F6829 Syntenin-1/MDA9 Antibody (Rabbit mAb) [B6B6] Apr 15 2026
F6704 DUSP1 Antibody (Rabbit mAb) [L5P15] Apr 15 2026
F5755 hnRNP L Antibody (Rabbit mAb) [G15K5] Apr 15 2026
E6682 CT-996(RO7795081，RG6652） CT‑996 (RO7795081, RG6652) is an orally active, cAMP‑biased agonist of GLP‑1R with an EC50 ≈ 0.049 nM for cAMP, with minimal β‑arrestin recruitment and receptor internalization, suitable for research on type 2 diabetes and obesity. Apr 14 2026
E0863 Talfirastide acetate Talfirastide acetate (TXA127 acetate; Angiotensin (1-7) acetate; Ang-(1-7) acetate) is an endogenous heptapeptide of the renin–angiotensin system (RAS) with a cardioprotective role due to its anti‑inflammatory and anti‑fibrotic activities in cardiac cells. It inhibits purified canine ACE activity with an IC50 of 0.65 μM and also acts as a local synergistic modulator of kinin‑induced vasodilation by inhibiting ACE and promoting nitric oxide release. Apr 14 2026
E6787 Rineterkib hydrochloride Rineterkib hydrochloride is an orally active, potent inhibitor of RAF and ERK1/2, exhibiting preclinical activity in multiple MAPK-activated cancer cell lines and xenograft models. Apr 14 2026
E6679 PhIP PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is a carcinogenic heterocyclic aromatic amine often generated in thermal processing of food. It induces DNA damage via CYP1A2 activation to hydroxylated metabolites forming C8-dG adducts and mutations. It also binds ERα to drive estrogenic signaling independent of genotoxicity, promoting epigenetic changes in MCF-7 breast cells akin to 17-β-estradiol, contributing to tissue-specific carcinogenesis in breast, colon, and prostate. Apr 13 2026
E0866 Glycerophosphoric acid Glycerophosphoric acid is a naturally occurring compound and an a‑site substrate analogue that, when bound to the a‑site, strongly inhibits the reaction of indole and nucleophilic indole analogues with E(A‑A). It also serves as a structural precursor of glycerophospholipids in cell membranes, contributing to membrane organization, fluidity, and transport regulation. Apr 12 2026