全ての製品

製品コード 製品名称 製品説明
S6475 Polaprezinc Polaprezinc (Aprozinate, Carnosine zinc complex, Zinc L-carnosine) is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities.
S9388 (+)-Praeruptorin A Praeruptorin A is a coumarin compound naturally occurring in the roots of Peucedanum praeruptorum Dunn., a commonly used traditional Chinese medicine for the treatment of certain respiratory diseases and hypertension. Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation. (+)-Praeruptorin A is one of enantiomers.
S7383 (-)-p-Bromotetramisole Oxalate (-)-p-Bromotetramisole Oxalate (L-p-Bromotetramisole Oxalate) is a potent and non-specific alkaline phosphatase inhibitor.
S2341 (-)-Parthenolide (-)-Parthenolide, an inhibitor of the Nuclear Factor-κB Pathway, specifically depletes HDAC1 protein without affecting other class I/II HDACs; Also promotes the ubiquitination of MDM2 and activates p53 cellular functions.
S6275 (−)-β-Pinene (−)-β-Pinene (Nopinene) is a natural organic compound in various plants. It is lethal to S. littoralis third instar larvae (LD50 = 65 μg/larva), inhibits infectious bronchitis virus (IBV) replication (IC50 = 1.32 mM) and exhibits a cytotoxic concentration (CC50) value of greater than 10 mM in Vero cells.
S5543 1, 10-Phenanthroline monohydrate 1,10-Phenanthroline is a classic chelating bidentate ligand for transition metal ions that has played an important role in the development of coordination chemistry. It is an inhibitor of metallopeptidases.
S6258 1,2-Propanediol 1,2-Propanediol (1,2-Dihydroxypropane, Propylene glycol, Methyl ethyl glycol) is a synthetic liquid substance that is commonly used as an excipient in a variety of drugs and it is also authorised in food products and cosmetics.
S6009 1-Phenyl-1,2-propanedione 1-Phenyl-1,2-propanedione (Acetyl benzoyl) is an eukaryotic metabolite produced during a metabolic reaction in plants.
E2908 1-PHENYL-2-THIOUREA 1-PHENYL-2-THIOUREA(N-Phenylthiourea, PTU, Phenylthiocarbamide) is an inhibitor of tyrosinase (Tyr). 1-PHENYL-2-THIOUREA blocks pigmentation and improves optical transparency in zebrafish (Danio rerio) embryo.
S2578 1-Phenylbiguanide 1-Phenylbiguanide (Phenylbiguanide, PBG, N-Phenylbiguanide) is a 5-hydroxytryptamine3 (5-HT3) receptor agonist with EC50 of 3.0 μM.
F2658 14-3-3 (pan) Antibody [N16K10] 14-3-3 (pan),pan 14-3-3
S5906 2,4-Pyridinedicarboxylic acid 2,4-Pyridinedicarboxylic acid (Lutidinic Acid, 2,4-Dicarboxypyridine, 2,4-PDCA) is a compound that structurally mimics 2-oxoglutarate (2-OG) and chelates zinc, thus affecting a range of enzymes. It blocks the activity of 2-OG oxygenases.
S9334 2-Pentylfuran 2-Pentylfuran (2-Amylfuran) is a naturally occuring flavouring ingredient.
S4440 2-Phenylacetamide 2-Phenylacetamide, the main compound isolated from the seeds of Lepidium apetalum Willd (LA) with estrogenic activities, increases the expression of Estrogen receptorα (ERα), ERβ and GPR30 in the uterus and MCF-7 cells.
S5347 2-Phenylethylamine 2-Phenylethylamine (β-Phenylethylamine, benzeneethanamine, β-aminoethylbenzene) is a natural monoamine alkaloid that functions as a monoaminergic neuromodulator or a neurotransmitter in the human central nervous system.,
S5346 2-Phenylethylamine hydrochloride 2-Phenylethylamine hydrochloride (β-Phenylethylamine, benzeneethanamine, β-aminoethylbenzene) is the hydrochloride salt form of 2-Phenylethylamine, which is an aromatic amine acting as a monoaminergic neuromodulator or a neurotransmitter in the human central nervous system.
S5877 2-Phenylimidazole

2-phenylimidazole (PhI, 2-Phenyl-1H-imidazole) is a corrosion inhibitor for brass and can be used to prepare complex compounds with ruthenium(III).

S6321 2-Phenylpropionic acid 2-Phenylpropionic acid (2-Phenylpropionate, Hydratropic acid, α-methyl-α-toluic acid) is an intermediate in alpha-Methylstyrene (2-phenylpropylene) metabolism.
S6317 2-Picolinic acid methyl ester 2-Picolinic acid methyl ester (Methyl picolinate, 2-Pyridinecarboxylic acid methyl ester, Methyl pyridine-2-carboxylate) is used as pharmaceutical intermediate.
S3597 3-Phenoxybenzoic acid 3-phenoxybenzoic acid (3-PBA), an intermediate metabolite of pyrethroids, is more toxic than its parent compounds and has been detected in milk, soil, and human urine.
S7639 3PO 3PO (3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one) is a small-molecule inhibitor of PFKFB3 with an IC50 of 22.9 μM for recombinant human PFKFB3 protein and does not inhibit PFK-1 activity. It suppresses glucose uptake, and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH.
S3592 4-PBA (4-Phenylbutyric acid) 4-PBA (4-Phenylbutyric acid) is a histone deacetylase (HDAC) inhibitor and a key epigenetic inducer of anti-HCV hepatic hepcidin. 4-Phenylbutyric acid inhibits LPS-induced inflammation through regulating endoplasmic-reticulum (ER) stress and autophagy in acute lung injury models.
S4125 4-PBA (Sodium Phenylbutyrate) 4-PBA (Sodium Phenylbutyrate) is a salt of 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid.Sodium phenylbutyrate is a histone deacetylase inhibitor, used to treat urea cycle disorders.
S6268 4-Pentenoic acid 4-Pentenoic acid (Allylacetic acid, 3-vinylpropionic acid, 4-penten-1-oic acid), a flavouring ingredient, is used to inhibit fatty acid oxidation in rat heart mitochondria.
S3978 5-Phenyl-2,4-pentadienoic acid 5-Phenyl-2,4-pentadienoic acid (5-Phenylpenta-2,4-dienoic acid) is used as Synthetic building block, anti-malarial agent.
S6096 5-Phenylvaleric Acid 5-Phenylvaleric acid (Benzenepentanoic acid, Phenylpentanoic acid, Phenylvaleric Acid) is a Pentanoic acid of bacterial origin, occasionally found in human biofluids.
S5551 6-Paradol 6-Paradol is a minor constituent of ginger, mainly formed from 6-gingerol via 6-shogaol, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities. Paradol is an inhibitor of cyclooxygenase (COX)-2.
E0028 9-Phenanthrol

9-Phenanthrol (9-Hydroxyphenanthrene, Phenanthren-9-o, 9-Phenanthrenol) is a selective TRPM4 inhibitor with an IC50 in the range of 0.02 μM, without effects on TRPM5.

F4829 P cadherin Antibody [B17B8]
F1045 P Glycoprotein Antibody [C5K22] CD243 (MDR-1),MDR1,MDR1/ABCB1,P Glycoprotein,P-Glycoprotein,P-Glycoprotein (MDR)
S5086 p-Anisaldehyde p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde), an extract from Pimpinella anisum seeds, exhibits antifungal activity against a number of yeast and mold strains in laboratory media, fruit purees and fruit juices.
S4759 p-Coumaric Acid p-Coumaric acid (4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant, anti-inflammatory, and antimicrobial activity.
S9564 p-Hydroxy-cinnamic Acid p-Hydroxy-cinnamic Acid has in vitro antimalarial activity and in vivo anti-osteoporotic properties.
S6008 p-Hydroxybenzaldehyde p-Hydroxybenzaldehyde (4-Hydroxybenzaldehyde, 4-Formylphenol, p-Formylphenol), which can be found in the orchids Gastrodia elata, Galeola faberi and vanilla, is a hydroxybenzaldehyde that reacts with NAD+ and H2O to produce 4-hydroxybenzoate, NADH, and 2 protons. p-Hydroxybenzaldehyde at 101.7 μM can significantly reduce the GABA-induced chloride current of GABAA receptors(α1β2γ2S subtype) expressed.
E1248 p-Nitrobenzyl mesylate p-Nitrobenzyl mesylate is an alkylating reagent for direct kinase substrate identification.
S6188 p-Toluenesulfonic acid monohydrate p-Toluenesulfonic acid (4-Methylbenzenesulfonic acid, Tosylic acid, tosic acid, para-toluene) is an extremely strong acidic compound.
E4074 p-Toluic acid p-Toluic acid (4-Methylbenzoic acid) is a methylbenzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc. It also exhibits hepatotoxicological potential in humanised-liver mice.
S8917 P110δ-IN-1 P110δ-IN-1 is an oral, potent and selective inhibitor of Phosphatidylinositol 3-Kinase (PI3K) P110δ with IC50 of 0.6 nM in cellular assay.
F1416 p115 RhoGEF Antibody [P4K2]
F0867 p130 Cas Antibody [P2F10] BCAR1,p130 Cas
F0536 p14 ARF Antibody [J3P11] CDKN2A/p14ARF,p14 ARF,p14ARF,p14ARF/CDKN2A
F1058 p18 INK4c/CDKN2C Antibody [G16B6] p18 INK4C,p18 INK4c/CDKN2C
F0170 p21 Waf1/Cip1 Antibody [F7M18] p21,p21 Waf1/Cip1,p21/CIP1/CDKN1A,p21/WAF1/Cip1,Waf1/Cip1/CDKN1A p21
S7133 P22077 P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
F4163 p22phox Antibody [G20B7]
F2538 p27 KIP 1 Antibody [A16H11] CDKN1B/Kip1 p27,p27,p27 KIP 1,p27 Kip1,p27[Kip1]
F0317 p27 Kip1 Antibody [F24A14] CDKN1B/Kip1 p27,p27,p27 KIP 1,p27 Kip1,p27[Kip1]
F1511 P2X7 Receptor Antibody [L17L11] P2X7,P2X7 Receptor
F0460 p35/25 Antibody [H17P2]
F0171 p38 MAPK Antibody [N23C2] Mitogen-activated protein kinase 14, MAP kinase 14; MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2,MAP kinase p38 alpha, MAP kinase p38 α, SAPK2a, MAP kinase 12; MAPK 12, ERK-6, ERK6, MAP kinase p38 gamma, MAPK12, SAPK3, MAP kinase 11; MAPK 11, MAP kinase p38 beta, p38b, SAPK2b, p38-2, MAPK11, PRKM11, SAPK2, SAPK2B, CSBP, CSBP1, CSBP2, MXI2, MAP kinase p38 γ,MAP kinase p38 gamma, Stress-activated protein kinase 3, MAP kinase p38 β, MAP kinase p38 beta, p38b
E2372 p38-α MAPK-IN-1 p38-α MAPK-IN-1 is an inhibitor of p38-α, with IC50 value of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.
F4658 p38α MAPK Antibody [N19P8]
F1221 p38α/MAPK14 Antibody [J11A5] Mitogen-activated protein kinase 14, MAP kinase 14; MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP MAP kinase MXI2, MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Mitogen-activated protein kinase p38 α, MAP kinase p38 α, Stress-activated protein kinase 2a, MAP kinase p38 alpha, SAPK2a, CSBP1, CSBP2, MXI2, Mitogen-activated protein kinase 11, Mitogen-activated protein kinase p38 beta, Mitogen-activated protein kinase p38 β, MAP kinase p38 beta, p38b, MAP kinase p38 β, Stress-activated protein kinase 2b, SAPK2b, p38-2, PRKM11, SAPK2, SAPK2B
F1367 p38δ MAPK Antibody [C13H14] p38 delta/MAPK13,p38δ MAPK
F3509 p44/42 MAPK (Erk1/2) Antibody [E11P7] ERK 1/2,ERK1 + ERK2,Erk1/2 (p44/p42),ERK1/ERK2,MAP Kinase (ERK-1, ERK-2),MAP Kinase, Non-Phosphorylated ERK,p44/42 MAPK (Erk1/2)
F0002 p44/42 MAPK (Erk1/2) Antibody [F1E12] Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, ERK1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p44-ERK1, PRKM3, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2,ERK2, PRKM1, PRKM2
F1466 p47phox Antibody [E24P19] NCF1/p47-phox,p47phox
F4804 p47phox Antibody [L8D20]
S7132 P5091 (P005091) P5091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM and the closely related USP47.
F2018 p53 (acetyl Lys 370) Antibody [L18F8]
F0020 p53 Antibody [F16A10] p53,p53 (pantropic),TP53
F4265 p57 Kip2 Antibody [E16C13]
F1401 p58IPK Antibody [M17H14]
F3974 p60 CAF1/MPP7 Antibody [J6B14]
E1462 P62-mediated mitophagy inducer P62-mediated mitophagy inducer (PMI) is a P62-mediated activator of mitophagy that functions independently of parkin recruitment or mitochondrial membrane potential (ΔΨm) collapse. It remains effective even in cells lacking a fully functional PINK1/Parkin pathway. PMI stabilizes Nrf2 and enhances p62 expression, thereby activating mitophagy.
F4735 p63 Antibody [C10M16]
F1148 p63 Antibody [C16H5]
F0767 p63-α Antibody [F10N6]
F3527 p70 S6 Kinase Antibody [B15P21] p70 S6 Kinase,p70 S6 kinase α,p70 S6 kinase/S6K1,S6K1
F0011 p70 S6 Kinase Antibody [D7E4] p70 S6 Kinase,p70 S6 kinase α,p70 S6 kinase/S6K1,S6K1
F2933 P70 S6 Kinase beta/SRK-N-terminal Antibody [G11B4] p70 S6 Kinase 2,P70 S6 Kinase beta/SRK,Phospho-(Ser/Thr) PKA Substrate,RPS6KB2
F1059 p73 Antibody [F14N9]
F4734 p73 Antibody [J24D9]
F0563 p75NTR Antibody [K22C18] CD271,Nerve Growth Factor Receptor,NGFR p75,p75 LNGFR,p75 NGF Receptor,p75NTR
S7968 P7C3 P7C3 is a potent proneurogenic and neuroprotective chemical that targets NAMPT enzyme.
S0287 P7C3-A20 P7C3-A20 is a highly active analogue of P7C3. P7C3-A20 is neuroprotective and promotes endogenous reparative strategies after TBI (Traumatic brain injury).
F0868 p95/NBS1 Antibody [B19M8] Nbs1,p95/NBS1
F1648 PABP1 Antibody [H6J19] PABP, PABP1
F2193 PABPN1 Antibody [G24K9] PABP2,PABPN1
S2738 PAC-1 PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3.
S8415 PACAP 1-38 PACAP 1-38 (Pituitary Adenylate Cyclase Activating Polypeptide 38) is a highly potent PACAP receptor agonist (Kd = 100 pM). It stimulates adenylate cyclase and phagocytosis.
S8416 PACAP 6-38 acetate PACAP 6-38 acetate is a PACAP (pituitary adenylate cyclase-activating polypeptide) non-stimulating competitive antagonist with an IC50 value of 2 nM. It also acts as a functional CARTp antagonist in vivo.
E0214 Pachymic acid Pachymic acid(3-O-Acetyltumulosic acid) inhibits the activity of CYP2C9 with the IC50 of 21.25 µM.
S1150 Paclitaxel Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy.
E6697 PACMA 31 PACMA 31 is an irreversible, orally active inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. It covalently binds PDI's active-site cysteines, inhibiting reductase/isomerase activity in a dose- and time-dependent manner per insulin aggregation assays.
S8057 Pacritinib (SB1518) Pacritinib is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3) with IC50s of 23 and 22 nM in cell-free assays, respectively. Phase 3.
F2996 PACT (PKR activating protein) / PRKRA Antibody [F4M5] PACT,PACT (PKR activating protein) / PRKRA
F2103 PADI4/PAD4 Antibody [B6N23]
S8444 Padnarsertib (KPT-9274, ATG-019) Padnarsertib (KPT 9274) is an orally bioavailable small molecule that is a non-competitive dual inhibitor of PAK4 and NAMPT. It shows an IC50 of ~120 nM for NAMPT in a cell-free enzymatic assay.
E0752 Paederoside Paederoside is a monoterpene S-methyl thiocarbonate isolated from Paederia pertomentosa and inhibits Epstein-Barr virus (EBV) early antigen (EA).
S2410 Paeoniflorin (NSC 178886) Paeoniflorin (NSC 178886,Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin reduces COX-2 expression. Paeoniflorin alleviates liver fibrosis by inhibiting HIF-1α through mTOR-dependent pathway.
S2339 Paeonol Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM.
F0743 PAI-1 Antibody [J4H7] PAI1,PAI-1,PAI-1/SERPINE1,Serpin E1/PAI-1
F3786 PAI1 Antibody [E17P19] PAI1,PAI-1,PAI-1/SERPINE1,Serpin E1/PAI-1
F3217 PAK1 Antibody [P10N18]
F1046 PAK2 Antibody [N15H3] Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2 , PAK-2, p58, PAK2, Serine/threonine-protein kinase PAK 3, Beta-PAK Oligophrenin-3, p21-activated kinase 3, PAK-3, PAK3, OPHN3, Serine/threonine-protein kinase PAK 1, Alpha-PAK,α-PAK, p21-activated kinase 1, PAK-1, p65-PAK
E1842 Palazestrant Palazestrant(OP-1250) is an orally bioavailable complete antagonist of estrogen receptor (ER) that blocks ER activity. It exhibits antiproliferative and antitumor activity in ER-positive (ER+) breast cancer models.
S4482 Palbociclib (PD-0332991) Palbociclib (PD 0332991) is a highly specific inhibitor of cyclin-dependent kinase 4 (Cdk4) and Cdk6 with IC50 of 11 nM and 16 nM, respectively.This product has poor solubility, animal in vivo experiments are available, cell experiments please choose carefully!
E6025 Palbociclib 2HCL Palbociclib 2HCL (PD-0332991 dihydrochloride), the dihydrochloride salt of Palbociclib, is a highly specific inhibitor of Cdk4 and Cdk6, with IC50 values of 11 nM and 16 nM, respectively. It is a potent antiproliferative agent against retinoblastoma (Rb)-positive tumor cells in vitro, inducing a selective G1 cell cycle arrest and reducing phosphorylation at Ser780 and Ser795 on the Rb protein.
S5840 Palifosfamide Palifosfamide (ZIO-201, Isophosphamide mustard) is a novel DNA alkylator and the active metabolite of ifosfamide with potential antineoplastic activity.
S1724 Paliperidone Paliperidone, the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist, used in the treatment of schizophrenia.
S5624 Paliperidone Palmitate Paliperidone Palmitate (9-hydroxyrisperidone palmitate) is a palmitate ester of paliperidone, which is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class.
F4554 Palladin Antibody [M23E22]
S3769 Palmatine Palmatine (Berbericinine, Burasaine), an isoquinoline alkaloid, has sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities.
S2397 Palmatine chloride Palmatine hydrochloride (Palmatine chloride (6CI,7CI); Fibrauretin) is a hydrochloride salt of palmatine which is a protoberberine alkaloid.
S3794 Palmitic acid Palmitic acid (Hexadecanoic acid, Cetylic acid) is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity. This product is a fatty acid that is almost insoluble in water-soluble solvents such as culture medium. It needs to be emulsified before use in cell experiments. It is recommended to purchase it in powder form.
S3341 Palmitoleic acid

Palmitoleic acid (POA, Palmitoleate) stimulates the uptake of glucose in liver through activation of AMPK and FGF-21, dependent on PPARα.

S4708 Palmitoylethanolamide Palmitoylethanolamide (PEA, Palmidrol, N-palmitoylethanolamine) is an endogenous fatty acid amide and selectively activates PPAR-α in vitro with an EC50 value of 3.1±0.4 μM.
S2238 Palomid 529 (P529) Palomid 529 (P529, SG 00529) inhibits both the mTORC1 and mTORC2 complexes, reduces phosphorylation of pAktS473, pGSK3βS9, and pS6. Phase 1.
S5740 Palonosetron Palonosetron (RS25259, RS 25259 197) is a 5-HT3 antagonist with Ki value of 0.17 nM. It is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
S3050 Palonosetron HCl Palonosetron HCl (RS 25259, RS 25259 197) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
E1445 Palovarotene Palovarotene (R 667; Ro 3300074) is a nuclear retinoic acid receptor γ (RAR-γ) agonist. It reduces heterotopic ossification (HO) in cultures and in murine and rat fibrodysplasia ossificans progressiva (FOP) models.
E2406 Paltusotine Paltusotine (CRN00808) is an orally active, nonpeptide selective somatostatin type 2 (SST2) receptor agonist, has the potential for maintaining GH and IGF-1 levels after depot somatostatin receptor ligand therapy.
E7472 Pam3CSK4 Pam3CSK4 (Pam3Cys-Ser-(Lys)4) is a synthetic triacylated lipopeptide that serves as a ligand for the Toll-like receptor 2/1 (TLR2/1) heterodimer. It is an agonist of toll-like receptor 1/2 (TLR1/2) with an EC50 of 0.47 ng/mL in human TLR1/2.
S5555 Pamabrom Pamabrom is a diuretic agent.
S8125 Pamapimod Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38gamma isoforms.
S0821 Pamicogrel Pamicogrel (KBT3022) is an inhibitor of cyclooxygenase (COX) with platelet anti-aggregatory properties.
S1311 Pamidronate Disodium Pamidronate Disodium (CGP 23339AE) is a nitrogen containing bisphosphonate, used to prevent osteoporosis.Pamidronate Disodium is a inhibitor of bone resorption factor.
E6057 Pamidronate disodium pentahydrate Pamidronate disodium pentahydrate is a nitrogen-containing bisphosphonate and used to prevent bone loss due to steroid use like glucocorticoid-induced low bone mineral density in children or to inhibit calcium release from bone by impairing osteoclast-mediated bone resorption. It also inhibits the Wnt/β-catenin signaling pathway that controls osteogenic differentiation in bone marrow mesenchymal stem cells (BMMSCs).
S8592 Pamiparib Pamiparib is a potent and selective inhibitor of PARP1 and PARP2 with IC50 values of 0.83 and 0.11 nM, respectively in biochemical assays. It shows high selectivity over other PARP enzymes.
E2660 Pamoic acid disodium Pamoic acid disodium, a potent GPR35 agonist with an EC50 value of 79 nM, induces GPR35a internalization and activates ERK1/2 with EC50 values of 22 nM and 65 nM, respectively, also potently recruits β-arrestin2 to GPR35 showing an antinociceptive effect.
A2042 Pamrevlumab (anti-CTGF) Pamrevlumab, a recombinant human antibody that binds to connective tissue growth factor (CTGF) has emerged as a potential therapy for idiopathic pulmonary fibrosis (IPF).
S6764 Pamufetinib (TAS-115) Pamufetinib (TAS-115) is a highly potent c-Met and VEGFR dual inhibitor with IC50s of 30 nM and 32 nM for recombinant VEGFR2 and recombinant MET, respectively.
F0771 Pan Cadherin Antibody [M17C10] Cadherin-2, CDw325, Neural cadherin, N-cadherin, CD325, CDH2, CDHN, NCAD, Cadherin-3, Placental cadherin, P-cadherin, CDH3, CDHP, Cadherin-1, CAM 120/80, Epithelial cadherin, E-cadherin, CD324, CDH1, CDHE, UVO, Cadherin-5, 7B4 antigen, Vascular endothelial cadherin, VE-cadherin, CD144, CDH5, Cadherin-4, Retinal cadherin, R-CAD, R-cadherin, CDH4
F3760 PAN TEAD Antibody [A12P9] Pan-TEAD,TEAD4/TEF-1
F1138 Pan Trk Antibody [B9H18] High affinity nerve growth factor receptor,Neurotrophic tyrosine kinase receptor type 1, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A Tyrosine kinase receptor, Trk-A, NTRK1, MTC, TRK, TRKA, NT-3 growth factor receptor, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, NTRK3, TRKC, BDNF/NT-3 growth factors receptor, Trk-B, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Tropomyosin-related kinase B
E1157 Pan-RAS-IN-1 Pan-RAS-IN-1, a pan-Ras inhibitor, binds to KRasG12D-GppNHp with a Kd less than 20 μM in MST, ITC and NMR assays, also binds to Ras proteins and exhibits lethality in cells partially dependent on expression of Ras proteins.
F0747 Pan-TEAD Antibody [L14N23] Transcriptional enhancer factor TEF-4, TEA domain family member 2, Transcriptional enhancer factor TEF-1, TEAD-2, TEAD2, TEF4, TEF-4, TEF-1, TEF1, NTEF-1, Protein GT-IIC, TEA domain family member 1, TEAD-1, TEAD1, Transcription factor 13, TCF-13, TCF13, TEAD-4, TEAD4, RTEF-1, RTEF1, TCF13L1, TEF3, TEF-3, TEF-5, TEF5, DTEF-1, DTEF1, TEAD-3, TEAD3, Transcriptional enhancer factor TEF-3, TEA domain family member 4, Transcription factor 13-like 1, Transcription factor RTEF-1, Transcriptional enhancer factor TEF-5, TEA domain family member 3
S3845 Panaxadiol Panaxadiol (20(R)-Panaxadiol) is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities. It inhibits Ca2+ channels, decreasing channel open time and open state probability in vitro and displaying anti-arrhythmic potential.
S3847 Panaxatriol Panaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities.
S4825 Pancreatin Pancreatin (Pancrelipase, Pancreatic enzymes), are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems.(PROTEASE ACTIVITY ≥ 275 USP.u/mg;Amvlase activity ≥ 275 USP.u/mg;Lipase Activity ≥ 22 USP.u/mg)
S2497 Pancuronium dibromide Pancuronium dibromide is a competitive nicotinic acetylcholine receptor antagonist, used as a muscle relaxant.
A2018 Panitumumab (anti-EGFR) Panitumumab (anti-EGFR, ABX-EGF) is a recombinant, fully human IgG2 monoclonal antibody that binds to the epidermal growth factor receptor (EGFR).
F1297 Pannexin-1 Antibody [C19F23]
S1030 Panobinostat (LBH589) Panobinostat (LBH589, NVP-LBH589) is a novel broad-spectrum HDAC inhibitor with IC50 of 5 nM in a cell-free assay. Panobinostat (LBH589) induces autophagy and apoptosis. Panobinostat effectively disrupts HIV latency in vivo. Phase 3.
S2105 Pantoprazole Pantoprazole (SKF96022, BY-1023) is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.
S4538 Pantoprazole sodium Pantoprazole (SKF96022, BY-1023) is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.
S5608 Pantoprazole sodium hydrate Pantoprazole (BY10232, SKF96022) sodium hydrate (Protonix) is a potent inhibitor of H+/K(+)-ATPase with IC50 of 6.8 μM.
E0378 PAP-1 PAP-1 (5-(4-phenoxybutoxy)psoralen), a Kv1.3 antagonist with an EC50 of 2 nM, inhibits the proliferation of human T cells and suppresses delayed type hypersensitivity in rats.
E0149 Papain

Papain (papaya proteinase I) is a sulfhydryl protease from the latex of the papaya fruit. Papain breaks down intercellular matrix of cartilage.

Papain can be used to induce animal models of Emphysema.
E0779 Paprotrain Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM.
S9963 Paquinimod (ABR-215757) Paquinimod (ABR 25757), a specific inhibitor of S100A8/A9, could rescue the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice.
E7144 PAR-4 Agonist Peptide, amide PAR-4 Agonist Peptide, amide (PAR-4-AP, AY-NH2) is a agonist of proteinase-activated receptor-4 (PAR-4) that provides antinociceptive effects in stress- and inflammation-induced hyperalgesia. It reduces visceral pain by activating PAR-4 receptors on colonic nerve terminals.
F1136 PAR2 Antibody [N9E12] PAR2,PAR-2
S2444 Parbendazole Parbendazole (SKF 29044) is an extremely potent inhibitor of microtubule assembly with IC50 of 3 µM for the assembly of brain microtubules.
S0104 Pardoprunox (SLV-308) hydrochloride Pardoprunox hydrochloride (DU-126891, SME-308) is a potent but partial dopamine D2 receptor agonist with pEC50 of 8.0, and a partial agonist in the induction of [35S]GTPγS binding with pEC50 of 9.2 and a serotonin 5-HT1A receptor agonist, with pEC50 of 6.3, respectively.
S4656 Parecoxib Parecoxib (SC-69124, Valus-P, Vorth-P) is a selective COX2 inhibitor.
S5418 Parecoxib Sodium Parecoxib Sodium (SC-69124) is a water-soluble, injectable sodium salt form of parecoxib, which is a potent and selective inhibitor of cyclo-oxygenase-2 (COX2).
E4823 Pargyline Pargyline is an irreversible selective inhibitor of monoamine oxidase (MAO) with Kis of 13 μM and 0.5 μM for MAO-A and MAO-B respectively. It has pharmaceutical potential as an anticancer drug for human prostate cancer.
S3690 Pargyline hydrochloride Pargyline is an irreversible inhibitor of monoamine oxidase (MAO)-B with Ki values of 13 and 0.5 μM for time-dependent inhibition of the activity of MAO-A and -B, respectivey.
S6681 Paricalcitol Paricalcitol is a selective vitamin D receptor agonist. Paricalcitol suppresses parathyroid hormone mRNA expression and inhibits parathyroid cell proliferation. Pariccitol is used to treat secondary hyperparathyroidism in chronic kidney disease.
S9049 Parishin A Parishin A, isolated from the rhizomes of Gastrodia elata, has good neuroprotective effects against brain disorders.
S9418 Parishin B Parishin B is a dominant active ingredient originating from Gastrodia elata Blume, and has good neuroprotective effects against brain disorders.
S5404 Paritaprevir (ABT-450) Paritaprevir (ABT-450) is a nonstructural (NS) protein 3/4A protease inhibitor.
F1047 PARK7/DJ1 Antibody [C10F17] DJ-1,PARK7/DJ1,Park7/DJ-1
F0296 Parkin Antibody [H15P18] PARK2,Parkin
F3602 PARN Antibody [L9K20]
S4183 Paromomycin Sulfate Paromomycin Sulfate(Aminosidine sulfate) is an aminoglycoside antibiotics inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA.
E4866 Paroxetine Paroxetine is a potent and selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety disorders. It inhibits pyroptosis and reduces osteoclast formation by blocking the NF-κB signalling pathway.
S3005 Paroxetine HCl Paroxetine HCl (BRL-29060A, FG-7051) is an antidepressant drug of the SSRI type.
S5239 Paroxetine mesylate Paroxetine Mesylate(BRL-29060A mesylate,FG-7051 mesylate) is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.
F2623 PARP1 Antibody [F9N15] PARP,PARP1
F0148 PARP1 Antibody [N4A5] PARP,PARP1
E0121 Parsaclisib (INCB050465)

Parsaclisib (INCB050465, INCB-50465, IBI376) is a potent and highly selective PI3Kδ(PI3K delta) inhibitor with an IC50 of 1 nM at 1 mM ATP in biochemical assay and approximately 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases.

F4591 Parvalbumin Antibody [J22P8]
A2430 Pascolizumab (Anti-IL-4) Pascolizumab (Anti-IL-4) is a humanized anti-IL-4 monoclonal antibody. Pascolizumab has the potential for asthma research. MW: 145.5 kD.
S4404 Pasiniazid Pasiniazid(Paraniazide,Pasiniazide) is a composition of isoniazid and 4-aminosalicylic acid, used to treat tuberculosis patients.
P1127 Pasireotide Pasireotide (SOM230) is a multi-receptor ligand somatostatin analogue with high binding affinity for somatostatin receptor (SSTR) subtypes sst1,2,3 and sst5. It potently suppresses GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing’s disease.
S3778 Patchouli alcohol Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
A2506 Patritumab (Anti-ERBB3 / HER3) Patritumab (Anti-ERBB3 / HER3) is a neutralizing monoclonal antibody targeting ERBB3. Patritumab shows a synergy with Cetuximab, potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors. MW: 145.5 KD.
D4004 Patritumab deruxtecan Patritumab deruxtecan (HER3-DXd) is an antibody-drug conjugate (ADC) composed of a fully human anti-HER3 IgG1 monoclonal antibody and a cytotixic topoisomerase I inhibitor. Patritumab deruxtecan shows anticancer activity.
S1364 Patupilone (Epothilone B) Patupilone (EPO906, Epothilone B) is a microtubule-stabilizing agent with EC0.01 of 1.8 μM. Phase 2.
F5076 PAX5 Antibody [A13D19]
F1006 PAX5 Antibody [M18F13] PAX5,Pax-5
F2154 PAX8 Antibody [J6L24]
S8163 Paxalisib (GDC-0084) Paxalisib (GDC-0084, RG7666) is a brain penetrant inhibitor of PI3K and mTOR with Kiapp values of 2 nM, 46 nM, 3 nM, 10 nM and 70 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR.
F1106 Paxillin Antibody [N7H16]
E1311 Paxilline Paxilline, an indole alkaloid mycotoxin derived from Penicillium paxilli, potently inhibits the BK channel by exerting its effects through direct channel inhibition. Additionally, Paxilline also functions as an inhibitor of sarco/endoplasmic reticulum Ca2+-stimulated ATPase (SERCA), with IC50 values ranging from 5 μM-50 μM, depending on the SERCA isoform. Paxilline also possesses significant anticonvulsant and neuroprotective effects.
S3012 Pazopanib (GW786034) Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms/CSF1R with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces cathepsin B activation and autophagy.
S1035 Pazopanib HCl Pazopanib HCl is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces autophagic Type II cell death.
S3621 Pazufloxacin mesylate Pazufloxacin Mesylate (T-3762, Pazucross), also known as Pazucross and T-3762, is a quinolone antibacterial agent used for the intravenous therapy of several infections.
E5948 PB94 PB94 is a potent and selective inhibitor of HDAC11 with an IC50 of 108 nM and exhibits >40-fold selectivity over other HDAC isoforms. It ameliorates neuropathic pain in mouse models and can be radiolabeled with carbon-11 as [¹¹C]PB94 for PET imaging, demonstrating significant brain uptake and potential for in vivo imaging applications.
S0529 PBD-150 PBD-150 is a potent human glutaminyl cyclase (hQC) Y115E-Y117E variant inhibitor with Ki of 60 nM.
E1733 PBIT PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes. It inhibits JARID1B (KDM5B/PLU1), JARID1Aand JARID1C with an IC50 of 3 μM, 6 μM and 4.9 μM respectively. It is capable of inhibiting the multiplication of breast cancer cell lines expressing high levels of JARIDB1.
F3332 PBK/SPK Antibody [L14M16] PBK/SPK,PBK/TOPK
F1584 PBR Antibody [G18J3] PBR,TSPO
S6549 PBTZ169 PBTZ169 (macozinone), an antibiotic with antimycobacterial activity, is an irreversible inhibitor of DprE1.
F3654 Pbx3 Antibody [A4N18]
F1491 PC Antibody [B18K17] PC2,PCSK2
F0642 PCAF Antibody [B2K11]
F3292 PCB Antibody [K5L1] PCB,Pyruvate Carboxylase
F4324 PCBP2 Antibody [L1D11]
F2812 PCDH7 Antibody [A6K3]
S6725 PCI 29732 PCI 29732 is a selective and irreversible Btk inhibitor with an IC50 of 0.5 nM.
S2012 PCI-34051 PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. PCI-34051 induces caspase-dependent apoptosis.
F4049 PCK1 Antibody [D3C9]
F0697 PCK1 Antibody [P16P6] PCK1,PCK1/PEPC
F1007 PCK2 Antibody [A2C10] PCK2 Rabbit mAb detects endogenous levels of total PCK2 protein.
F0018 PCNA Antibody [N10L6] PCNA,Proliferating Cell Nuclear Antigen
S4476 PCNA-I1 PCNA-I1 is a selective inhibitor of proliferating cell nuclear antigen (PCNA, a potential anticancer target). PCNA-I1 selectively binds to PCNA trimers with Kd of ~0.2 to 0.4 μM. PCNA-I1 inhibits the growth of tumor cells of various tissue types with IC50 of ~0.2 μM. PCNA-I1 induces DNA damage and apoptosis in both LNCaP and PC-3 cells. PCNA-I1 also induces autophagy in PC-3 cells.
E1889 PCO371 PCO371 is a nonpeptidyl, orally active agonist of Parathyroid hormone type 1 receptor (PTHR1). It stimulates cAMP production in COS-7 cells with an EC50 of 2.4 μmol/L. It also acts as an osteoporosis drug and significantly enhances bone mineral density (BMD) and bone strength in the lumbar vertebrae of osteopenic ovariectomized (OVX) rats. It also restores normal serum calcium levels without increasing urinary calcium in hypocalcemic thyroparathyroidectomized (TPTX) rats.
F2761 PCSK9 Antibody [F3K11]
F2760 PCSK9 Antibody [M4L6]
S7395 PD 150606 PD150606 is a potent and selective inhibitor of calpainwith Ki values of 0.21 µM for µ-calpain and 0.37 µM for m-calpain. It exhibits neuroprotective effects by reducing hypoxic/hypoglycemic injury in cerebrocortical neurons and excitotoxic damage in cerebellar Purkinje cells.
S5183 PD 169316 PD 169316 is a potent, selective and cell-permeable p38 MAP kinase inhibitor with IC50 of 89 nM. PD169316 abrogates signaling initiated by both TGFbeta and Activin A. PD169316 shows antiviral activity against Enterovirus71.
S1177 PD 98059 PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) and functions as an AHR antagonist.
S1116 PD-0332991 (Palbociclib) Hydrochloride Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
S1579 PD-0332991 (Palbociclib) Isethionate Palbociclib Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
S8158 PD-1/PD-L1 Inhibitor 3 PD-1/PD-L1 Inhibitor 3(Programmed Death-1/Programmed Death-Ligand 1 Inhibitor 3)is a Macrocyclic inhibitor of PD-1/PD-L1 interaction with IC50 of 5.6 nM
S8493 PD-166866 PD-166866 is a synthetic molecule inhibiting the tyrosin kinase action of FGFR1, shows a very high selectivity towards FGFR1 and inhibits the auto-phosphorylation activity of FGRF1.
F2853 PD-L1 Antibody [G4H2] CD274 (PD-L1, B7-H1),PD-L1
F2670 PD-L1 Antibody [P4L19] CD274 (PD-L1, B7-H1),PD-L1
F4028 PD-L2 Antibody [C11K4]
F0551 PD-L2 Antibody [K17B13]
S8148 PD0166285 PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations (IC50=24 nM for Wee1 and 72 nM for Myt1). PD0166285 is also a novel G2 checkpoint abrogator. PD0166285 induces apoptosis.
S1036 PD0325901 (Mirdametinib) Mirdametinib (PD0325901) is a selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM in cell-free assays, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2. Phase 2.
S7098 PD123319 PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.
S2168 PD128907 HCl PD 128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor.
S6956 PD146176

PD146176 (NSC168807) is a potent inhibitor of 15-lipoxygenase (15-LO) with Ki of 197 nM for rabbit reticulocyte 15-LO.

S6546 PD153035 PD153035 is a specific and potent inhibitor of the epidermal growth factor (EGF) receptor tyrosine kinase (Ki = 5.2 pM).
S1079 PD153035 HCl PD153035 HCl (SU-5271 HCl, AG1517 HCl, ZM 252868 HCl) is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM in cell-free assays; little effect noted against PGDFR, FGFR, CSF-1, InsR and Src.
S7039 PD168393 PD168393 is an irreversible EGFR inhibitor with IC50 of 0.70 nM, irreversibly alkylate Cys-773; inactive against insulin, PDGFR, FGFR and PKC.
S1264 PD173074 PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosis in gastric cancer cells.
E1368 PD173212 PD173212(Compound 11) is a selective N-type voltage sensitive calcium channel (VSCC) blocker, with an IC50 of 36 nM in IMR-32 assays.
S7269 PD173955 PD173955 is a potent Bcr-Abl inhibitor with IC50 of 1-2 nM, also inhibiting Src activity with IC50 of 22 nM.
S0739 PD184161 PD184161, an orally active MEK inhibitor with IC50 of 10-100 nM in a time- and concentration-dependent manner, inhibits cell proliferation and induces apoptosis, and produces depressive-like behavior.
F0489 PDCD4 Antibody [N11F3] PDCD4,Pdcd-4
F3297 PDCD4 Antibody [P19F6] PDCD4,Pdcd-4
F3476 PDCD6/ALG-2 Antibody [D6F22]
S8862 PDD00017273 PDD00017273 is a potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor with an IC50 of 26 nM. PDD00017273 exhibits >350-fold selectivity for PARG over a panel of ion channels, enzymes and receptors, including PARP1 and ARH3.
S0627 PDEC-NB PDEC-NB is a disulfide cleavable linker that can be applied into the synthesis of antibody-drug conjugates (ADCs).
F0237 PDGF Receptor β Antibody [H10B5] PDGF Receptor beta/PDGFR-β,PDGF Receptor β,PDGFR beta
S8721 PDGFR inhibitor 1 PDGFR inhibitor 1 is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of Kit (c-Kit) and PDGFR with potential antineoplastic activity. It also inhibits several other kinases, including VEGFR2, TIE2, PDGFR-beta and CSF1R, thereby further inhibiting tumor cell growth.
F4076 PDGFR α Antibody [E14D18]
F3240 PDGFR α Antibody [P1E17] PDGF Receptor alpha/PDGFR-α,PDGF Receptor α,PDGFR alpha
F1540 PDGFR α/β Antibody [C19P10]
F3190 PDHB Antibody [B10A22]
F0392 PDHK1 Antibody [J6P24] PDHK1
F3123 PDI Antibody [C9H24]
F0238 PDI Antibody [M24L14] P4HB,PDI,Protein Disulfide Isomerase/P4HB
F3393 PDK1 Antibody [E12L3] PDHK1
F1103 PDK1 Antibody [P9M7] [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, Pyruvate dehydrogenase kinase isoform 1, PDH kinase 1, PDK1, PDHK1, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4, PDK4, PDHK4, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial, Pyruvate dehydrogenase kinase isoform 3, PDK3, PDHK3, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial, Pyruvate dehydrogenase kinase isoform 2, PDH kinase 2, PDKII, PDK2, PDHK2
F2345 PDK2 Antibody [L2A10]
F2759 PDK4 Antibody [C15G7]
E5843 PDK4-IN-1 hydrochloride PDK4-IN-1 hydrochloride is an anthraquinone-derived, orally active allosteric inhibitor of PDK4 with an IC50 of 84 nM, exhibiting anticancer activity by regulating cell proliferation, transformation, and apoptosis. It also exhibit antidiabeti and anti-allergic activity.
S0155 PDM-11 PDM-11 is a derivative of resveratrol that exhibits stronger antagonist affinity for arylhydrocarbon receptors (AhR) than resveratrol, without any affinity for the estrogen receptor.
S6560 PDM2 PDM2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
F3890 PDPK1 Antibody [K10G23]
E1484 PDS-0330 PDS-0330 is an inhibitor of Claudin-1, which inhibits claudin1-mediated signalling by interfering with its binding to Src. PDS-0330 exhibits an antitumor effect and enhances apoptosis in colorectal cancer cells.
S3633 PDTC (Pyrrolidinedithiocarbamate ammonium) PDTC (Pyrrolidinedithiocarbamate ammonium) is a potent nuclear factor-κB (NF-κB) inhibitor that inhibits IκB phosphorylation, blocks NF-κB translocation to the nucleus and reduces the expression of downstream cytokines.
F3781 PDX1 Antibody [E2L13]
F0646 Pdx1 Antibody [F18P8]
F3134 PEA3 Antibody [L14H15] ETV4,Pea3
E1050 PEAQX PEAQX (NVP-AAM077) is an effective and orally available human NMDA antagonist, which shows preference in excess of 100-fold for hNMDA 1A/2A (IC50=of 270 nM) over hNMDA 1A/2B receptors (IC50=29,600 nM).
E1877 Pebezertinib (BLU-451, LNG-451) Pebezertinib is a central nervous system (CNS)-penetrant, wild-type EGFR-sparing, covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM. It also exhibits a potent anti-tumor efficacy.
E2955 Pectin Pectin is a heteropolysaccharide, derived from the cell wall of higher plants. It involves in the formation of nanoparticles as a delivery vehicle of agents. It also acts as an adsorbent, a broad-spectrum antimicrobial agent that binds to bacteria toxins and other irritants in the intestinal mucosa, relieves irritated mucosa.
S3255 Pectolinarigenin Pectolinarigenin, an active anti-inflammatory ingredient in Cirsium chanroenicum, is a dual inhibitor of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX).
S9054 Pectolinarin Pectolinarin is a major compound in Cirsium setidens with anti-inflammatory activity. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin induces apoptosis via inactivation of the PI3K/Akt pathway.
S9501 Pedunculoside Pedunculoside is a novel triterpene saponin extracted from the dried barks of Ilex rotunda Thunb, showing lipid-lowering effects.
S7650 Peficitinib (ASP015K) Peficitinib is an orally bioavailable JAK inhibitor. Phase 3.
S1855 Pefloxacin Mesylate Pefloxacin Mesylate(Pefloxacinium mesylate) is a synthetic chemotherapeutic agent and an antibacterial agent with IC50 of 6.7 nM.
S4119 Pefloxacin Mesylate Dihydrate Pefloxacin Mesylate Dihydrate (1589 RB,Pefloxacinium mesylate dihydrate) is the third generation of fluoroquinolone class of antibacterials, which inhibits Topoisomerase II activity and DNA replication.
S6704 PEG300 PEG300 (Polyethylene glycol 300) is a water-miscible polyether widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries. It serves as a kind of solubilizer, excipient, lubricant, and chemical reagent. PEG300 helps in the formation of hydrogels in situ upon mixing with silk. These PEG–silk hydrogels are of interest for many biomedical applications, such as anti-fouling and anti-adhesion.
S6705 PEG400 PEG400b (Polyethylene glycol 400) is a commonly used co-solvent used in a variety of pharmaceutical formulations. It acts as a good solubilizer and surfactant and has the potential to improve the bioavailability of drugs. PEG400 significantly accelerates the metabolism of baicalein and increases the penetration of BG and B6G in Caco‐2 cells.
S9281 Peimine Peimine (Verticine, Wanpeinine A) is a major biologically active component of Fritillaria ussuriensis, exhibits anti-inflammatory and pain suppression properties at the cellular level.
S9148 Peiminine Peiminine (Verticinone, Zhebeinone, Raddeanine), a biologically active component extracted from Fritillaria walujewii Regel, has been reported to have potent anti-inflammatory, antitussive, and expectorant effects. It induces autophagic cell death thus represses colorectal carcinoma tumor growth.
S7853 Pelabresib (CPI-0610) Pelabresib (CPI-0610) is a potent and selective benzoisoxazoloazepine BET bromodomain inhibitor with an IC50 of 39 nM for BRD4-BD1 in TR-FRET assay and currently undergoing human clinical trials for hematological malignancies. CPI-0610 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.
A2912 Pelgifatamab (Anti-FOLH1 / PSMA) Pelgifatamab (anti-FOLH1 / PSMA) is an immunoglobulin G1-kappa monoclonal antibody targated against FOLH1 (folate hydrolase, prostate-specific membrane antigen, psma). MW: 146.24 KD.
S1392 Pelitinib (EKB-569) Pelitinib (EKB-569) is a potent irreversible EGFR inhibitor with IC50 of 38.5 nM. Pelitinib (EKB-569) also slightly inhibits Src, MEK/ERK and ErbB2 with IC50s of 282 nM, 800 nM and 1255 nM, respectively. Phase2.
F3720 Pellino 1 Antibody [H22B1] Pellino 1,Pellino-1
A2005 Pembrolizumab (anti-PD-1) Pembrolizumab (anti-PD-1) is a potent, highly selective, fully humanized immunoglobulin (Ig) G4-kappa monoclonal antibody against PD-1 with potential immune checkpoint inhibitory and antineoplastic activities. MW : 146.286 KD.
S5971 Pemetrexed Pemetrexed (LY231514) is a novel antifolate and antimetabolite for thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT) with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.
E4818 Pemetrexed (disodium heptahydrate) Pemetrexed (disodium heptahydrate) is a folate antimetabolite that inhibits thymidylate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyltransferase. It also induces apoptosis and cell-cycle arrest in non-small-cell lung cancer carrying an EGFR exon 19 deletion.
S1135 Pemetrexed Disodium (LY231514) Pemetrexed disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.
S7785 Pemetrexed Disodium Hydrate Pemetrexed Disodium Hydrate (LY-231514) is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. Pemetrexed Disodium Hydrate stimulates autophagy and apoptosis.
S0088 Pemigatinib (INCB054828) Pemigatinib is an orally active and selective inhibitor of FGFR with IC50 of 0.4 nM, 0.5 nM, 1.2 nM and 30 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.
S4008 Pemirolast potassium Pemirolast potassium (BMY26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.
S5725 Pempidine Pempidine (Pyrilene, Perolysen, 1,2,2,6,6-Pentamethylpiperidine) is a long-acting ganglion-blocking compound.
F1441 PEN2 Antibody [B8C20]
F4810 PEN2 Antibody [E13J21]
S9470 Penbutolol Sulfate Penbutolol sulfate ((-)-Terbuclomine) is an effective beta-adrenergic receptor blocker and diuretic that is used as an antihypertensive agent.
S4184 Penciclovir Penciclovir (BRL-39123, VSA 671,NSC-759624) is a purine acyclic nucleoside analogue with potent antiviral activity.
S4151 Penfluridol Penfluridol (TLP-607,R-16341) is a highly potent, first generation diphenylbutylpiperidine antipsychotic.
S1853 Penicillamine Penicillamine (Dimethyl Cysteine) is used as an antirheumatic and as a chelating agent in Wilson’s disease.
E6075 Penicillin G benzathine tetrahydrate Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is a long-acting beta-lactam antibiotic effective against many bacterial infections such as impetigo.
S5515 Penicillin G Procaine Procaine benzylpenicillin (Procaine benzylpenicillin,PGP), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
S4160 Penicillin G Sodium Penicillin G Sodium (Benzylpenicillin) is a β-lactam antibiotic produced by Penicillin spp.
S3650 Penicillin V potassium salt Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
E2894 Penicillin-Streptomycin Penicillin-Streptomycin is used to prevent microbial contamination of cell culture during long-term in vitro cell culture maintenance. 100× solution stabilized with 10,000 units penicillin and 10 milligrams streptomycin per milliliter, suitable for cell culture applications.
E0674 Pennogenin 3-O-β-chacotrioside Pennogenin 3-O-beta-chacotrioside, an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1, and posesses anti-colorectal cancer activity.
S6234 Pentadecanoic acid Pentadecanoic acid is a saturated fatty acid of exogenous (primarily ruminant) origin. It also has a role as a plant metabolite, a food component, a Daphnia magna metabolite, a human blood serum metabolite and an algal metabolite.
E4864 Pentamidine Pentamidine (MP-601205) is an aromatic diamidine drug, an antagonist of TLR4.It also inhibits PI3K/AKT signaling pathway and reduce the expression of MMP-2 and MMP-9. It exhibits anti- protozoal, anti-inflammatory, and anti-tumor activities and is used as an agent for treating African trypanosomiasis, antimony resistant leishmaniasis and Pneumocystis carinii pneumonia.
S4007 Pentamidine isethionate Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.
S5746 pentetate calcium trisodium hydrate pentetate calcium trisodium hydrate (Ca-DTPA) is an iron chelating agent.
S4824 Pentetic Acid Pentetic Acid (Diethylenetriaminepentaacetic acid, DTPA, Acidum penteticum, Detapac, Detarex) is an aminopolycarboxylic acid that is used similar to EDTA, sequestering metal ions.
S3500 Pentosan Polysulfate Sodium Pentosan Polysulfate Sodium (PPS, Elmiron) is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also exhibits anti-HIV-1 activity.
S9521 Pentostatin Pentostatin(CI-825,Deoxycoformycin) is a potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
S4345 Pentoxifylline Pentoxifylline is a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF and leukotriene synthesis, and reduces inflammation and innate immunity.
S4143 Pentoxyverine Citrate Pentoxyverine Citrate (Carbetapentane) is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold.
F2748 Pentraxin 3/PTX3 Antibody [M10M8]
S4587 Pentylenetetrazol Pentylenetetrazol (Pentylenetetrazole, Metrazole, pentetrazol, pentamethylenetetrazol, Corazol, Cardiazol, PTZ) displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GABA(A) receptor antagonist.Pentylenetetrazol can be used to induce animal models of (Acute or Chronic) Epilepsy.
S6788 PEO-IAA PEO-IAA (2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid) is a novel potent auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs). PEO-IAA suppresses not only the expression of an auxin-responsive ZmSAUR2 gene, but also gravitropic curvature.
A2361 Pepinemab (Anti-SEMA4D / CD100) Pepinemab (Anti-SEMA4D / CD100) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), which is a regulator of neuronal development and plays a role in a variety of cellular processes. MW : 145.5 kD.
S7381 Pepstatin A Pepstatin A (Pepstatin) is a potent aspartic protease inhibitor, and also inhibits HIV replication. Pepstatin A is also an inhibitor of cathepsins D and cathepsins E. Pepstatin A inhibits autophagy by suppressing lysosomal proteases.
E6410 Peptide 4 Peptide 4 is a complex synthetic peptide molecule commonly used as a research chemical or therapeutic agent due to its potential to mimic biological peptides and modulate specific molecular targets.
P1125 Peptide YY (3-36) (human)

Peptide YY (3-36) (human) is an endogenous appetite suppressing peptide. Peptide YY (PYY) (3-36), Human, a neuropeptide Y (NPY) Y2 receptor agonist, is a powerful inhibitor of intestinal secretion[1].

P1126 Peptide YY (human)

Peptide YY (PYY) is a gut hormone that regulates appetite and inhibits pancreatic secretion. Peptide YY (PYY) can mediate its effects through the Neuropeptide Y receptors.

S2716 Peramivir Trihydrate Peramivir Trihydrate (BCX-1812, RWJ-270201, S-021812) is a trihydrate of the anti-infection agent peramivir which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
E2867 perflexane Perflexane (Perfluorohexane) is a fluoroalkane that function as a radioopaque medium and a non-polar solvent. It is used as a contrast agent for ultrasound imaging.
S3501 Perflubron Perflubron (1-Bromoperfluorooctane, Perfluorooctyl bromide, Oxygent, PFOB) exhibits anti-inflammatory activity thus decreases cytokine production in human alveolar macrophages. Perflubron also attenuates oxidative damage to both biological and nonbiological systems which is independent of its anti-inflammatory properties.
F2444 Perforin Antibody [P20D17]
S6959 Perhexiline maleate Perhexiline maleate is a potent inhibitor of carnitine palmitoyltransferase 1 (CPT1) with IC50s of 77 μM and 148 μM for rat heart CPT1 and liver CPT1, respectively, and also inhibits carnitine palmitoyltransferase 2 (CPT2).
S1037 Perifosine Perifosine is a novel Akt inhibitor with IC50 of 4.7 μM in MM.1S cells, targets pleckstrin homology domain of Akt. Phase 3.
S3205 Perillaldehyde Perillaldehyde (Perilladehyde, Perillal, PAE, PA), the main component of Perilla frutescens (a traditional medicinal antioxidant herb), inhibits BaP-induced AHR activation and ROS production, inhibits BaP/AHR-mediated release of the CCL2 chemokine, and activats the NRF2/HO1 antioxidant pathway.
S9006 Perillartine Perillartine (Perilla sugar, Peryllartine) is a sweetener. Perillartine can activation of the Tas1r2 monomeric receptors of human, rhesus monkey and squirrel monkey but not mouse in a species-dependent manner.
S3853 Perillyl alcohol Perillyl alcohol (Perilla alcohol, Isocarveol) is a monoterpene isolated from the essential oils of lavendin, peppermint, spearmint, cherries, celery seeds, and several other plants.
E6037 Perindopril Perindopril (S-9490) is a brain-penetrating inhibitor of angiotensin-converting enzyme (ACE) with an IC50 of 0.048 μM for ACE-1. It exhibits anti-hypertensive, anti-inflammatory, and anti-fibrotic properties.
S1506 Perindopril Erbumine Perindopril Erbumine (S9490-3) is a pro-drug and metabolized in vivo by hydrolysis of the ester group to form Perindoprilat, the biologically active metabolite, a potent ACE inhibitor with IC50 of 1.05 nM. Perindopril Erbumine is used for in vivo studies and Perindoprilat is recommened for in vitro research.
E2435 Perindopril L-Arginine Perindopril L-Argininel is a prodrug that is metabolized in the liver to its active diacid metabolite perindoprilat, which is rapidly and extensively absorbed, and become one of the highest tissue angiotensin-converting enzyme (ACE) affinities among the ACE inhibitors.
F3854 Periostin Antibody [C16F13]
F3997 Peripherin Antibody [P7B12]
S9181 Periplocin Periplocin (Periplocoside), extracted from the traditional herbal medicine cortex periplocae, has cardiac and anticancer activity. Periplocin could significantly boost proliferation, migration and stimulate collagen production in fibroblast L929 cells, which is dependent on activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase, and thus promoting wound healing.
S9168 Periplogenin Periplogenin (Desoxostrophanthidin, 5-beta-Hydroxydigitoxigenin), isolated from Lagenaria siceraria, has potent anti-psoriatic effects in vitro and in vivo.
F4128 PERK Antibody [A22L11]
F0027 PERK Antibody [L1C15] PERK,p-ERK
S5185 Perospirone Perospirone (SM-9018 free base) is an orally active antagonist of 5-hydroxytryptamine2 (5-HT2) receptor, dopamine2 (D2) receptor and 5-HT1A receptor with Ki of 0.6 nM, 1.4 nM and 2.9 nM, respectively.
S4889 Perospirone hydrochloride Perospirone (SM-9018) is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.
E7194 Peroxidase, Horseradish Peroxidase, Horseradish is an archetypal haem-containing enzyme that uses hydrogen peroxide or alkyl peroxides to catalyze oxidative reactions, including the hydroxylation and polymerization of aromatic compounds. It is commonly used as a detection enzyme in biochemical assays like ELISA, Western blotting, and immunohistochemistry, due to its ability to produce strong colorimetric or chemiluminescent signals for sensitive and specific detection.
F1664 Peroxiredoxin 2/PRP Antibody [K23N23] Peroxiredoxin 2/PRP,PRDX2
F3198 Peroxiredoxin 3/PRDX3 Antibody [E17K19]
F2838 Peroxiredoxin 6 Antibody [G12J13] Peroxiredoxin 6,PRDX6
S4731 Perphenazine Perphenazine (Perphenazin, Trilafon, Etaperazine) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
A2008 Pertuzumab (anti-HER2) Pertuzumab (anti-HER2), a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors, impairs the ability of HER2 to bind to other members of the HER family, MW: 148 KD.
A2474 Petosemtamab (Anti-EGFR / LGR5) Petosemtamab (Anti-EGFR/LGR5) is a highly potent bispecific antibody against EGFR (Kd 0.22 nM) and LGR5 (Kd 0.86 nM). It blocks the appearance of metastases and slows the growth of primary tumors in experimental cancer models. Petosemtamab can be used in the research of solid tumors, such as head and neck squamous cell carcinoma (HNSCC), metastatic colorectal cancer (CRC). MW: 145.5 KD.
S3342 Petroselinic acid

Petroselinic acid (PSA) is a positional isomer of oleic acid isolated from the vegetable oil of Coriandrum sativum fruits. Petroselinic acid can be used for the fermentation of new sophorolipids.

E1953 Pevonedistat hydrochloride Pevonedistat hydrochloride (MLN4924 hydrochloride) is a potent and selective inhibitor of NEDD8-activating enzyme (NAE) with an IC50 of 4.7 nM. It disrupts cullin-RING ligase-mediated protein degradation, leading to apoptotic cell death in human tumor cells through the deregulation of S-phase DNA synthesis.
F2617 PEX19 Antibody [P24A3]
S7818 Pexidartinib (PLX3397) Pexidartinib (PLX3397) is an oral, potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R, Kit (c-Kit), and FLT3 with IC50 of 20 nM, 10 nM and 160 nM, respectively. Pexidartinib (PLX3397) induces apoptosis and necrosis with antitumor activity. Phase 3.
E6007 Pexidartinib Hydrochloride Pexidartinib Hydrochloride is an oral tyrosine kinase inhibitor of colony-stimulating factor 1 receptor (CSF1R). It significantly reduces macrophage levels in adipose tissue without altering overall myeloid cell counts in mice. It also induces developmental and immunotoxic effects in zebrafish embryos by hyperactivating Wnt signaling.
S7799 Pexmetinib Pexmetinib is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.
S6418 PF 429242 PF 429242 is known as a S1P inhibitor with an IC50 of 170 nM, showing no significant inhibition of trypsin, elastase, proteinase K, plasmin, kallikren, factor XIa, thrombin, or furin at concentrations up to 100 μM and only modest inhibition of urokinase (IC50 = 50 μM) and factor Xa (IC50 = 100 μM).
S2249 PF 4800567 PF 4800567 is a novel and potent inhibitor of casein kinase 1 epsilon (IC50=32 nM) with greater than 20-fold selectivity over casein kinase 1 delta(IC50=711 nM).
S9731 PF-00835231 PF-00835231 is a 3CLpro (Mpro) inhibitor that may targets SARS-CoV-2 protease 3CLpro as a potential new treatment for COVID-19.
S1068 PF-02341066 (Crizotinib) Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines.
S1094 PF-04217903 PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM in A549 cell line, susceptible to oncogenic mutations (no activity to Y1230C mutant). Phase 1.
S7211 PF-04418948 PF-04418948 is a potent and selective prostaglandin EP₂ receptor antagonist with IC50 of 16 nM. Phase 1.
S2421 PF-04457845 PF-04457845 (PF-4457845) is a potent, favorable selective inhibitor of Fatty acid amide hydrolase (FAAH) with IC50 of 7.2 nM and 7.4 nM for hFAAH and rFAAH, respectively. PF-04457845 covalently modifies the active-site serine nucleophile of FAAH with exquisite selectivity relative to other members of the serine hydrolase superfamily.
S7192 PF-04620110 PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
S2743 PF-04691502 PF-04691502 (PF4691502) is an ATP-competitive PI3K(α/β/δ/γ)/mTOR dual inhibitor with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. PF-04691502 induces apoptosis. Phase 2.
E2819 PF-04802367 PF-04802367 (PF-367) is a highly selective Glycogen synthase kinase-3 (GSK-3) inhibitor with IC50s of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.
S2656 PF-04929113 (SNX-5422) PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2.
E2983 PF-04957325 PF-04957325 is a highly potent and selective inhibitor of PDE8, with IC50 values of 0.7 nM and 0.3 nM for PDE8A and PDE8B, respectively. PF-04957325 greatly potentiates steroidogenesis in wild type adrenal cells.
S0496 PF-04995274 PF-04995274 (PF-4995274) is a potent, high-affinity, orally active and partial agonist of serotonin 4 receptor (5-HT4R) with EC50 of 0.47 nM, 0.36 nM, 0.37 nM and 0.26 nM for human 5-HT4A/4B/4D/4E, respectively. As for rat 5-HT4S/4L/4E, the EC50 is 0.59 nM, 0.65 nM and 0.62 nM, respectively. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease.
S6672 PF-05175157 PF-05175157 is a broad-spectrum effective ACC inhibitor with IC50 of 27.0 nM, 33.0 nM, 23.5 nM and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively.
S6145 PF-05221304 PF-05221304 is an orally bioavailable, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), an enzyme that catalyzes the first committed step in de novo lipogenesis (DNL).
E1927 PF-05251749(CK1-IN-2) PF-05251749 (CK1-IN-2, Compound Nr.4) is a potent, selective, brain-penetrant inhibitor of Casein Kinase 1 (CK1) in a concentration-dependent manner, with IC50 values of 33.1 nM for CK1d and 51.6 nM for CK1e. It also functions as an inducer of CYP3A, with the potential to treat circadian rhythm disruptions in Alzheimer's and Parkinson's diseases.
S8407 PF-06273340 PF-06273340 is a highly potent, kinases elective, well-tolerated pan-Trk inhibitor with IC50 values of 6, 4, 3 nM for TrkA, TrkB, Trk C, respectively.
S6648 PF-06282999 PF-06282999 is an orally bioavailable, irreversible inactivator of myeloperoxidase enzyme and is currently in clinical trials for the potential treatment of cardiovascular diseases.
S8335 PF-06409577 PF-06409577 is an orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms.
S9921 PF-06424439 Methanesulfonate

PF-06424439 is a first orally bioavailable small-molecule inhibitor of DGAT2 with an IC50 of 14 nM.

S0849 PF-06446846 PF-06446846 is an orally active proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. PF-06446846 selectively inhibits translation of PCSK9 by stalling the 80S ribosome in the proximity of codon region.
E0116 PF-06446846 hydrochloride PF-06446846 (PF846) Hydrochloride is an orally bioavailable and specific inhibitor of PCSK9 with an IC50 of 0.3 µM in Huh7 cells.
S8202 PF-06447475 PF-06447475 is a potent, selective, and brain penetrant LRRK2 kinase inhibitor with IC50 of 3 nM.
S8538 PF-06651600 (Ritlecitinib) Ritlecitinib (PF-06651600) is a potent and irreversible JAK3-selective inhibitor with an IC50 of 33.1 nM but without activity (IC50 > 10 000 nM) against JAK1, JAK2, and TYK2.
S9655 PF-06821497 PF-06821497 is a selective and orally active inhibitor of Zeste Homolog 2 (EZH2) with a Ki value <0.1 nM against mutant Y641N EZH2. It exhibits robust tumor growth inhibition.
S8657 PF-06840003 PF-06840003 (EOS200271) is a highly selective orally bioavailable IDO-1 inhibitor. Although it has moderate hIDO1 enzyme inhibition (IC50 0.41 μM), it is a highly efficient compound (LE 0.53, LipE 5.1), driven by its tight packing within the enzyme, as well as the high density of hydrogen bonds it forms with hIDO-1 despite its small size.
S0036 PF-06869206 PF-06869206 is a selective inhibitor of NPT2a (also referred to as NaPi2a or SLC34A1) with an IC50 of 380 nM.
S8816 PF-06873600 (Ebvaciclib) PF-06873600 is an inhibitor of cyclin-dependent kinase 2 (CDK2), CDK4, and CDK6 with Ki values of 0.1, 1.2, and 0.1 nM, respectively, blocks the phosphorylation of retinoblastoma protein (RB1), and limits the proliferation of OVCAR-3 ovarian cancer cells with EC50s of 19 and 45 nM, respectively.
S9615 PF-06928215 PF-06928215 is a high affinity inhibitor of cyclic GMP-AMP synthase (cGAS) with an IC50 of 4.9 μM.
E1785 PF-06952229 PF-06952229(UNII-1KKS7U3X86) is a selective, orally available inhibitor of the serine/threonine kinase TGF-β receptor 1 (TGF-β-R1). It inhibits pSMAD2 in both tumor and immune cells, reducing TGF-β signalling and reversing EMT in vitro. It modulates the tumor immune microenvironment and shows antitumor activity in mouse models.
E1495 PF-07220060 (CDK4/6-IN-6) PF-07220060 (CDK4/6-IN-6) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively.
E5816 PF-07265028 PF-07265028 is a potent and selective inhibitor of hematopoietic progenitor kinase 1 (HPK1/MAP4K1) with a Ki of <0.05 nM, and exhibits potent cellular activity, with a pSLP76 IC50 of 17 nM.
E1818 PF-07265807 PF-07265807(TAM&Met-IN-1) is a dual inhibitor of AXL and MER, which exhibits anti-tumor effects. It also enhances the function of dendritic cells to cross-prime CD8+ T cells.
E5970 PF-07853578 PF-07853578 (Example 11) is a degrader of Patatin-Like Phospholipase Domain-Containing Protein 3(PNPLA3) with an EC50 of 5.2 nM. It may be useful for the treatment and prevention of liver diseases, including fatty liver, nonalcoholic fatty liver disease (NALFD), nonalcoholic steatohepatitis (NASH), liver fibrosis, cirrhosis, and hepatocellular carcinoma.
S8224 PF-3644022

PF-3644022 is a potent freely reversible ATP-competitive inhibitor of MAPKAPK2 (MK2) with an Ki of 3 nM. PF-3644022 also potently inhibits TNFα production with an IC50 of 160 nM.

S2222 PF-3716556 PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+,K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+,K+-ATPase, used for the treatment of gastroesophageal reflux disease.
S7094 PF-3758309 PF-03758309 (PF-03758309) is a potent, ATP-competitive, pyrrolopyrazole inhibitor of PAK4 with Kd of 2.7 nM. PF-3758309 is antiproliferative and induces apoptosis in a HCT116 tumor model.
S2666 PF-3845 PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
S8361 PF-4136309 PF-4136309 (INCB8761, PF-04136309) is a potent, selective, and orally bioavailable CCR2 antagonist with an IC50 of 5.2 nM for human CCR2.
S7644 PF-431396 PF-431396 is a dual PYK2/FAK inhibitor with IC50 of 11 nM and 2 nM, respectively.
S2163 PF-4708671 PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM in cell-free assays, 400-fold greater selectivity for S6K1 than S6K2, and 4- and >20-fold selectivity for S6K1 than MSK1 and RSK1/2, respectively. PF-4708671 induces autophagy. First S6K1-specific inhibitor to be reported.
S2904 PF-477736 PF-477736 (PF-736, PF-00477736) is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM in a cell-free assay and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~100-fold selectivity for Chk1 than Chk2.
S2921 PF-4981517 PF-4981517 (CYP3cide, PF-04981517) is a potent and selective inhibitor of CYP3A4 (P450) with IC50 of 0.03 μM, exhibits >500-fold selectivity over CYP3A5 and CYP3A7.
S7675 PF-4989216 PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.
S2777 PF-5274857 PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the blood–brain barrier.
S7177 PF-543 hydrochloride PF-543 hydrochloride, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM, exhibits >100-fold selectivity over the SphK2 isoform. PF-543 hydrochloride induces apoptosis, necrosis, and autophagy.
S2890 PF-562271 (VS-6062) PF-562271 (PF-00562271) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
S2672 PF-562271 Besylate PF-562271 Besylate is the benzenesulfonate salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.
S7357 PF-562271 HCl PF-562271 HCl is the hydrochloride salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.
S2013 PF-573228 PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β. PF-573228 induces apoptosis.
S6499 PF-6260933 PF-6260933 (PF-06260933) is a potent inhibitor of MAP4K4 with an IC50 of 3.7 nM, possessing excellent kinome selectivity.
S6734 PF-670462 PF-670462 is a potent and selective inhibitor of CK1ε and CK1δ with IC50 value of 90 nM and 13 nM, respectively.
E0146 PF-9363 (CTx-648) PF-9363 is a potent and selective KAT6A/6B inhibitor with Ki of 0.41 nM and 1.2 nM for KAT6A and KAT6B, respectively. PF-9363 displays potent anti-tumor activity in ER+ breast cancer models.

S0435 PF-9366  PF-9366 is a human methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 420 nM and Kd of 170 nM.
F3421 PF4 Antibody [L7F2] CXCL4/PF4,PF4
E0788 PfDHODH-IN-2 PfDHODH-IN-2, a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (pfDHODH) inhibitor with an IC50 of 1.11 µM, acting as an antimalarial agent which can be used for the research of malaria.
E0998 PFE-360 PFE-360(PF-06685360) is a brain-penetrant and selective LRRK2 small-molecule kinase inhibitors.
S1216 PFI-1 (PF-6405761) PFI-1 (PF-6405761) is a highly selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM and for BRD2 with IC50 of 98 nM in a cell-free assay.
S7294 PFI-2 HCl PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.
S7315 PFI-3 PFI-3 is a selective chemical probe for SMARCA bromodomains, including SMARCA2, SMARCA4 and PB1(5) bromodomains.
S7906 PFI-4 PFI-4 is a potent and selective BRPF1 bromodomain inhibitor with IC50 of 80 nM.
E4657 PFI-6 PFI-6 is a selective MLLT1/3 probe that targets the YEATS domain of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3) with IC50 values of 140 nM and 160 nM for MLLT1 and MLLT3, respectively. PFI-6 demonstrates increased affinity and selectivity for MLLT1/3 than other human YEATS domain proteins (YEATS2/4).
S9882 PFI-90 PFI-90 is a selective inhibitor of the histone demethylase KDM3B. PFI-90 induces apoptosis and cell differentiation resulting in delayed tumor progression in vivo.
S7289 PFK-015 PFK15 (PFK-015) is a potent and selective 6-phosphofructo-2-kinase (PFKFB3) inhibitor with IC50 of 207 nM.
S8807 PFK158 PFK158 is a potent and selective inhibitor of PFKFB3. It has improved PK properties and causes ~80% growth inhibition in several mouse models of human-derived tumors.
F1479 PFKFB2 Antibody [E19B24]
F5036 PFKFB2 Antibody [P13H13]
F4675 PFKFB3 Antibody [A21K14]
F1204 PFKFB3 Antibody [M5H12] 6 Phosphofructo 2 Kinase,PFKFB3
F3155 PFKM + PFKL Antibody [K8F12]
F3597 PFKM + PFKP Antibody [B11E20]
F2565 PFKM Antibody [F13D16] PFK-1,PFKM
F0698 PFKP Antibody [E13C9]
S3549 PFM01 PFM01, a cell-permeable N-alkylated Mirin derivative, is a selective inhibitor of MRE11 endonuclease activity.
F1652 PGC 1β Antibody [N23E23] Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-beta, PGC-1-β, PPAR-gamma coactivator 1-beta; PPARGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
F4188 PGC-1α Antibody [J17F10]
F4416 PGC1α/β Antibody [H5N22]
F1626 PGK1 Antibody [D17A1]
F1137 PGP9.5 Antibody [L3K10] PGP9.5,Protein Gene Product 9.5,UCHL1,UCH-L1/PGP9.5
F1408 PGRMC1 Antibody [F1M7]
S0082 PH-002 PH-002 is an inhibitor of Apolipoprotein E4 (ApoE4) intracellular domain interaction in nerve cells.
S3451 PH-064 PH-064 (BIM-46187) is a novel imidazo-pyrazine derivative that inhibits the heterotrimeric G-protein complex effectively. PH-064 (BIM46174) inhibits heterotrimeric G-protein signalling in GPCRsthat mediate cyclic AMP generation (GAs), calcium release (GAq), cancer cell invasion by Wnt-2 frizzled receptors, and high-affinity neurotensin receptors (GAo/i and GAq).
S2726 PH-797804 PH-797804 is a novel pyridinone inhibitor of p38α with IC50 of 26 nM in a cell-free assay; 4-fold more selective versus p38β and does not inhibit JNK2. Phase 2.
S1070 PHA-665752 PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9 nM in cell-free assays, >50-fold selectivity for c-Met than RTKs or STKs.
S1454 PHA-680632 PHA-680632 is a potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
S2742 PHA-767491 HCl PHA-767491 (CAY10572, NMS 1116354) HCl is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM in cell-free assays, respectively.It displays ~20-fold selectivity against CDK1/2 and GSK3-β, 50-fold selectivity against MK2 and CDK5, 100-fold selectivity against PLK1 and CHK2.
S1487 PHA-793887 PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM. It is greater than 6-fold more selective for CDK2, 5, and 7 than CDK1, 4, and 9. PHA-793887 induces cell-cycle arrest and apoptosis. Phase 1.
E6459 Phaclofen Phaclofen is a selective antagonist of GABAB receptor. Phaclofen is a peripheral and central baclofen antagonist that is used in determining the physiological significance of central and peripheral bicuculline-insensitive receptors with which GABA and (-)-baclofen interact.
S3240 Phaseoloidin Phaseoloidin, a homogentisic acid glucoside from Nicotiana attenuata trichomes, contributes to the plant's resistance against lepidopteran herbivores. Phaseoloidin has anti-complement effects.
F1345 PHB2 Antibody [F9A16] PHB2,Prohibitin 2
E2168 PHD-1-IN-1 PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM
F0587 PHD-2/Egln1 Antibody [C1P15] EGLN1/PHD2,PHD-2/Egln1
S9172 Phellodendrine Phellodendrine, a quaternary ammonium alkaloid extracted from the dried bark of Phellodendrom chinensis Schneid and Phellodendrom amurense Rupr, has the effect of suppressing cellular immune response, reducing blood pressure and antinephritis.
S9245 Phellodendrine chloride Phellodendrine chloride, isolated from the Phellodrndron amurensis, exhibits immunosuppressive and anti-inflammatory activities.
E1070 Phen-DC3 Trifluoromethanesulfonate Phen-DC3 Trifluoromethanesulfonate is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65 ± 6 and 50 ± 10 nM, respectively.
S2577 Phenacetin Phenacetin (Acetophenetidin) is a non-opioid analgesic without anti-inflammatory properties.
E6460 Phenamil methanesulfonate Phenamil methanesulfonate, is a potent and less reversible inhibitor of epithelial sodium channel (ENaC) with an IC50 of 400 nM. Phenamil methanesulfonate is also a competitive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca2+ transport with an IC50 of 140 nM in a Ca2+ uptake assay. Phenamil methanesulfonate is used for the research of cystic fibrosis lung disease.
S5037 Phenazine methosulfate Phenazine methosulfate (N-Methylphenazonium methosulfate, 5-Methylphenazinium methyl sulfate) is widely used as an intermediate electron carrier for coupling the production of NADH or NADPH to the reduction of tetrazolium salts to coloured formazans.
S4235 Phenazopyridine HCl Phenazopyridine HCl is a local analgesic that has been used in urinary tract disorders. It is an inhibitor of sodium channel protein type 1 subunit alpha.
E0165 Phenelzine sulfate

Phenelzine Sulfate is a hydrazine derivative and acts as a potent non-selective monoamine oxidase (MAO) inhibitor with an IC50 of 0.9 μM.

S3703 Phenethyl alcohol Phenethyl alcohol (2-phenylethanol, 2-Phenylethyl alcohol, Benzeneethanol, Phenylethanol) is an antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
S2542 Phenformin HCl Phenformin HCl is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class. It activates AMPK, increasing activity and phosphorylation.
S4892 Phenibut (β-Phenyl-GABA) Phenibut (Aminophenylbutyric acid, Fenibut, Phenigam, Phenybut, PhGABA, β-Phenyl-γ-aminobutyric acid, β-Phenyl-GABA), a GABA analogue, is a central nervous system depressant with anxiolytic and sedative effects.
S5520 Phenidone Phenidone (1-phenyl-3-pyrazolidinone), a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), is an organic compound that is primarily used as a photographic developer.
S1921 Phenindione Phenindione (Rectadione, phenylindandione) is an anticoagulant which functions as a Vitamin K antagonist.
S4045 Pheniramine Maleate Pheniramine Maleate is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.
E7437 Phenol Red Phenol red (Phenolsulfonephthalein) is a pH indicator dye commonly used in cell culture media, where it changes color from yellow to red based on pH levels. It also participates in redox reactions, particularly in the presence of enzymes like myeloperoxidase, influencing cellular oxidative states without directly causing significant toxicity.
S4418 Phenol Red sodium salt Phenol Red sodium salt (Phenolsulfonephthalein sodium salt) is used ubiquitously as a pH indicator in tissue culture media ranging from 6.8 (yellow) to 8.2 (red). Phenol red binds to the estrogen receptor of MCF-7 human breast cancer cells.
S5395 Phenolphthalein Phenolphthalein (Phthalimetten) is an acid-base pH indicator.
S4251 Phenothiazine Phenothiazine (ENT 38) is a dopamine-2 (D2) receptor antagonist therefore decreases the effect of dopamine in the brain.
L8500 Phenotypic Screening Library A unique collection of 4209 bioactive compounds with identified targets used for phenotypic Screening.
S9634 Phenoxodiol (Haginin E) Phenoxodiol (Haginin E, Idronoxil, Dehydroequol, NV 06, PXD) is an isoflavone analog with antineoplastic activity that activates the caspase system, inhibits XIAP (X-linked inhibitor of apoptosis), and disrupts FLICE inhibitory protein (FLIP) expression, resulting in tumor cell apoptosis. Phenoxodiol also inhibits DNA topoisomerase II.
S2499 Phenoxybenzamine HCl Phenoxybenzamine HCl (NSC 37448, NCI-c01661) is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.
S2188 Phenprocoumon Phenprocoumon (Marcoumar, Marcumar and Falithrom,Ro 1-4849) is a vitamin K reductase with an IC50 of 1 μM
E6046 phentolamine hydrochloride Phentolamine hydrochloride is a potent, selective, and orally active antagonist of α1 and α2 adrenergic receptors , with pKi values of 8.8, 8.0, and 8.3 for the human α2A, α2B, and α2C adrenergic receptors, respectively. It also shows binding affinities for the α1-adrenoceptor subtypes, exhibiting Ki values of 6.1 nM for cloned α1A/D, 39.8 nM for α1B, and 2.8 nM for α1C.
S2038 Phentolamine Mesylate Phentolamine Mesylate(Phentolamine methanesulfonate) is a reversible and nonselective alpha-adrenergic receptor antagonist, used for the prevention or control of hypertensive episodes.
S6051 Phenyl-ac-Gly-OH Phenyl-ac-Gly-OH (N-(2-Phenylacetyl)glycine, 2-Phenylacetyl glycine, Phenaceturic acid, Phenacetylglycine) is one of acyl glycines that are normally minor metabolites of fatty acids.
S9357 Phenylacetaldehyde Phenylacetaldehyde (Hyacinthin, Phenylethanal) is an organic compound used in the synthesis of fragrances and polymers.
S6076 Phenylacetylglutamine Phenylacetylglutamine is a product formed by the conjugation of phenylacetate and glutamine. It is a normal constituent of human urine, but other mammals such as the dog, cat, rat, monkey, sheep, and horse do not excrete this compound.
E4016 Phenylarsine oxide Phenylarsine oxide (Oxophenylarsine) is a membrane-permeable protein tyrosine phosphatase inhibitor with IC50 18 µM. It Stimulates 2-deoxyglucose transport in insulin-resistant human skeletal muscle.
S1654 Phenylbutazone Phenylbutazone (Butazolidine) is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.
S2569 Phenylephrine HCl Phenylephrine HCl is a selective α1-adrenergic receptor agonist, used primarily as a decongestant.
S5425 Phenylglyoxal hydrate Phenylglyoxal (1-Phenylethanedione) is a potent inhibitor of mitochondrial aldehyde dehydrogenase. It reacts with arginine residues in purified Hageman factor (HF, Factor XII) and causes inhibition of its coagulant properties.
S6053 Phenylglyoxylic acid Phenylglyoxylic acid (Benzoyl formate, Phenylglyoxalic acid, Phenylglyoxylate) is a key building block in the field of chemical synthesis and is widely used to synthesize pharmaceutical intermediates or food additives.
S2525 Phenytoin Phenytoin (Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722) is an inactive voltage-gated sodium channel stabilizer.
S2524 Phenytoin Sodium Phenytoin Sodium (Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt; Phenytek,Dilantin sodium, Diphantoine) is an inactive voltage-gated sodium channel stabilizer.
S5348 Pherocon (4-(4-Acetoxyphenyl)-2-butanone) Pherocon (4-(4-Acetoxyphenyl)-2-butanone, 4-(p-Acetoxyphenyl)-2-butanone, 4--(3-Oxobutyl)phenyl acetate) is a standard melon fly attractant for detection programs.
F3416 PHF1 Antibody [M20F24]
F2637 PHF20 Antibody [B7L16]
F1406 PHGDH Antibody [M2L10] PHGDH,PHGDH/Malate dehydrogenase
E1437 PHI-101 PHI-101 is an orally active, potent third-generation inhibitor of FLT3 that overcomes resistance to multiple drug-resistant mutations. It has potential for research in relapsed or refractory acute myeloid leukemia (AML).
S9187 Phillygenin Phillygenin (Sylvatesmin), a bioactive intergradient in Osmanthus fragrans, has anti-inflammatory, anti-obesity and antipyretic activities. It could reduce blood lipid levels and low density lipoprotein.
S8418 Phleomycin D1 Phleomycin D1(PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. It causes cell death by binding and cleaving DNA. It shows antiproliferative activities and strong cytotoxicity against HT-29 cells.
S4784 Phloracetophenone Phloracetophenone, or 2,4,6-trihydroxyacetophenone (THA), the aglycone component of phloracetophenone glucoside, is a naturally occurring compound obtained from the rhizome of Curcuma comosa (Family Zingiberaceae). Phloracetophenone can stimulate CYP7A1 activity. Phloracetophenone induces cholestasis in rats mediated through Mrp2.
S3795 Phloretic acid Phloretic acid (Desaminotyrosine, Hydro-p-coumaric acid, Phloretate, 3-(4-Hydroxyphenyl)propanoic acid) is a naturally occurring phenolic compound which can be produced by the hydrogenation of p-coumaric acid or synthesized from phloretin, a by-product of apple tree leaves.
S2342 Phloretin (RJC 02792) Phloretin (RJC 02792, NSC 407292, Dihydronaringenin) is a dihydrochalcone found in apple tree leaves, which shows beneficial effects on diabetes.
S2343 Phlorizin Phlorizin (Phloridzin) is a dihydrochalcone found in the bark of pear (Pyrus communis), apple, cherry and other fruit trees. Phlorizin is a non-selective SGLT inhibitor with Ki of 300 nM and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.
S9389 Phorbol Phorbol is a natural, plant-derived organic compound that exerts a broad range of biological activities.
E2961 Phosphatase substrate Phosphatase substarte (4-Nitrophenyl phosphate disodium hexahydrate, p-nitrophenyl phosphate disodium hexahydrate) is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. It is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm.
S3335 Phospho(enol)pyruvic acid monopotassium salt

Phospho(enol)pyruvic acid monopotassium salt (Potassium 1-carboxyvinyl hydrogenphosphate) is an endogenous metabolite.

F3048 Phospho-(Ser) 14-3-3 Binding Motif Antibody [P9J15]
F4182 Phospho-4E-BP1 (Ser65) Antibody [K24A12]
F0339 Phospho-4E-BP1 (Ser65) Antibody [K8A20] p-4E-BP1
F0150 Phospho-4E-BP1 (Thr37/46) Antibody [E9G24]
F0851 Phospho-4E-BP1 (Thr70) Antibody [K18C18]
F3507 Phospho-Akt (Ser473) Antibody [B19D19] p-Akt1/2/3,phospho akt1/pkbalpha (ser473),Phospho-Akt (Ser473)
F0699 Phospho-Akt (Thr450) Antibody [J1B12] RAC-beta serine/threonine-protein kinase, Protein kinase Akt-2, PKB beta 1, RAC-PK-beta, RAC-gamma serine/threonine-protein kinase, Akt-3, PKB gamma, RAC-PK-gamma, STK-2, AKT3, PKBG, RAC-alpha serine/threonine-protein kinase, PKB, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, AKT1
F4918 Phospho-Akt1 (Ser129) Antibody [K23C4]
F2636 Phospho-Akt1 (Ser129) Antibody [N19C7] AKT1 (phospho S129),Phospho-Akt1 (Ser129)
F4087 Phospho-Akt1 (Ser473) Antibody [K10L8]
F4050 Phospho-AKT1 (Thr450) Antibody [H24E24]
F1644 Phospho-AKT1/2/3 (Ser473/474/472) Antibody [B6L18]
F0493 Phospho-Akt2 (Ser474) Antibody [L16H11] AKT2 (phospho S474),Phospho-Akt2 (Ser474)
F4092 Phospho-AMPA Receptor 1 (GluA1) (Ser831) Antibody [D9B24]
F1561 Phospho-AMPK α1/α2 (Thr183/172) Antibody [C21K7]
F3514 Phospho-AMPKα (Thr172) Antibody [E15N20]
F0591 Phospho-AMPKα1 (Ser485) Antibody [E13G1]
F3294 Phospho-AMPKα1 (Ser496) Antibody [K3H21]
F1967 Phospho-AP2M1 (Thr156) Antibody [H5H7] AP2M1 (phospho T156),Phospho-AP2M1 (Thr156)
F0768 Phospho-APP (Thr668) Antibody [F3G1]
F1382 Phospho-AS160 (Ser318) Antibody [F11E8]
F0748 Phospho-AS160 (Ser588) Antibody [A11K10]
F2944 Phospho-ATF1 (Ser63) Antibody [P2B10]
F2830 Phospho-ATF2 (Thr71) Antibody [F15L17] p-ATF-2
F2435 Phospho-ATR (Ser428) Antibody [H24J12] ATR (phospho S428),Phospho-(Ser/Thr) Akt Substrate,Phospho-ATR (Ser428)
F0241 Phospho-Aurora A/B/C (T288/232/198) Antibody [H12A24] Aurora 3,Aurora/IPL1-related kinase 3, ARK-3, ARK3, Aurora/IPL1/Eg2 protein 2, STK13, Serine/threonine-protein kinase 13, Serine/threonine-protein kinase aurora-C, Aurora 1, AIM-1, ARK-2, ARK2, Aurora-related kinase 2, AURKC, AIE2, AIK3, AIRK3, ARK3, STK-1, Serine/threonine-protein kinase 12, AURKB, AIK2, AIRK2, STK1, STK12, STK5, Aurora 2, Aurora/IPL1-related kinase 1, ARK-1, Aurora-related kinase 1, Breast tumor-amplified kinase, Ipl1- and aurora-related kinase 1, Serine/threonine-protein kinase 15, AURKA, AIK1, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6, Aurora- and IPL1-like midbody-associated protein 1, Aurora/IPL1-related kinase 2
F2054 Phospho-B MyB (Thr487) Antibody [B21K19]
F0445 Phospho-Bad (Ser112) Antibody [K3H8] Bad (phospho S112),Phospho-Bad (Ser112)
F0394 Phospho-Bad (Ser136) Antibody [K15E21]
F0977 Phospho-BTK (Tyr223) Antibody [H3N9] BTK (phospho Y223),Phospho-Btk (Tyr223)
F0405 Phospho-c-Fos (Ser32) Antibody [H14J15]
F1069 Phospho-c-Jun (Ser63) Antibody [A1M19] c-Jun (phospho S63),c-Jun (phospho S73),p-c-Jun,Phospho-c-Jun (Ser63),Phospho-c-Jun (Ser63) II,Phospho-c-Jun (Ser73)
F4072 Phospho-c-Jun (Ser63) Antibody [E24K1]
F3070 Phospho-c-Jun (Ser73) Antibody [H24P6]
F0654 Phospho-c-Kit (Tyr703) Antibody [K16C2] c-Kit (phospho Y703),Phospho-c-Kit (Tyr703)
F1606 Phospho-c-Myb (Ser11) Antibody [B4K10]
F1220 Phospho-c-Myc (Ser62) Antibody [F8C4] c-Myc (phospho S62),MYC (phospho S62),Phospho-c-Myc (Ser62)
F4625 Phospho-c-Myc (Ser62) Antibody [M18C23]
F2474 Phospho-c-Myc (Thr58) Antibody [L1K9] c-Myc (phospho T58),Phospho-c-Myc (Thr58)
F0353 Phospho-c-Raf (Ser338) Antibody [F15C8]
F0342 Phospho-CaMKII (Thr286) Antibody [L21H4] Calcium/calmodulin-dependent protein kinase type II subunit beta, Calcium/calmodulin-dependent protein kinase type II subunit delta, Calcium/calmodulin-dependent protein kinase type II subunit gamma, Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit beta, CaMK-II subunit beta, CAMK2B, CAM2, CAMK2, CAMKB, CaM kinase II subunit delta; CaMK-II subunit delta, CAMK2D, CAMKD, CaM kinase II subunit gamma; CaMK-II subunit gamma, CAMK2G, CAMK, CAMK-II, CAMKG,CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968, CaMK-II β, CaMK-II δ, CaMK-II γ, CaMK-II α
F3156 Phospho-CD3 ζ (Tyr142) Antibody [N6L15]
F2899 Phospho-CD3 ζ (Tyr83) Antibody [G11P19]
F0306 Phospho-cdc2 (Tyr15) Antibody [P12H8] CDK1 (phospho Y15),Phospho-cdc2 (Tyr15)
F3558 Phospho-CDC2(Thr161) Antibody [F10B10]
F0406 Phospho-cdc25C (Ser216) Antibody [D12E13] Cdc25C (phospho S216),Phospho-cdc25C (Ser216)
F1949 Phospho-cdc25C (Thr48) Antibody [G24N3]
F4240 Phospho-CDC37 (Ser13) Antibody [G22K18]
F3185 Phospho-CDK1 (T161) + CDK2/3 (T160) Antibody [G17G2]
F2120 Phospho-CDK1/2/3 (Thr14) Antibody [L12G24] Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, CDC2, CDC28A, CDKN1, P34CDC2, Cyclin-dependent kinase 2, Cell division protein kinase 2 p33 protein kinase, CDK2, CDKN2, Cyclin-dependent kinase 3, Cell division protein kinase 3, CDK3, CDKN3
F2387 Phospho-CDK1/2/3/5 (Tyr15) Antibody [B6L9]
F2496 Phospho-CDK2 (Thr14) Antibody [F10F1]
F3552 Phospho-CDK2 (Thr160) Antibody [N24F24]
F5055 Phospho-Chk1 (Ser296) Antibody [F19D13]
F0495 Phospho-Chk1 (Ser317) Antibody [N9E3]
F0242 Phospho-Chk1 (Ser345) Antibody [P19M4] Chk1 (phospho S345),Phospho-Chk1 (Ser345)
F0243 Phospho-Chk2 (Thr68) Antibody [L12K12]
F0244 Phospho-Cofilin (Ser3) Antibody [G14H6] Cofilin (phospho S3),Phospho-Cofilin (Ser3)
F2953 Phospho-Cofilin (Ser3) Antibody [G1C13] Cofilin (phospho S3),Phospho-Cofilin (Ser3)
F1346 Phospho-Connexin 43 (Ser368) Antibody [J12F20] Connexin 43 / GJA1 (phospho S368),Phospho-Connexin 43 (Ser368)
F1943 Phospho-cPLA2 (Ser505) Antibody [L10N8] Cytosolic Phospholipase A2 (phospho S505),Phospho-cPLA2 (Ser505)
F0154 Phospho-CREB (Ser133) Antibody [K11M21] CREB (phospho S133),Phospho-CREB (Ser133)
F2525 Phospho-CREB (Ser133) Antibody [M20D18] CREB (phospho S133),Phospho-CREB (Ser133)
F4234 Phospho-CrkL (Tyr207) Antibody [B13N10]
F0593 Phospho-Cyclin D1 (Thr286) Antibody [P16A10]
F2175 Phospho-DNA PKcs (Ser2056) Antibody [M17B5] DNA PKcs (phospho S2056),Phospho-DNA-PKcs (Ser2056)
F0594 Phospho-DRP1 (Ser637) Antibody [J22A19] DRP1 (phospho S637),Phospho-DRP1 (Ser637)
F1394 Phospho-EGF Receptor (Thr669) Antibody [H18D23]
F3557 Phospho-EGF Receptor (Tyr1045) Antibody [F16D14]
F0298 Phospho-EGF Receptor (Tyr1068) Antibody [J6N1] EGFR (phospho Y1068),Phospho-EGF Receptor (Tyr1068)
F4089 Phospho-EGF Receptor (Tyr1173) Antibody [E8J4]
F0749 Phospho-EGF Receptor (Tyr845) Antibody [K14C19]
F2845 Phospho-EGFR (Tyr1068) Antibody [F6A14] EGFR (phospho Y1068),Phospho-EGF Receptor (Tyr1068)
F1627 Phospho-EGFR (Tyr1086) Antibody [A18B1] EGFR (phospho Y1086),Phospho-EGF Receptor (Tyr1086)
F3968 Phospho-EGFR (Tyr1101) Antibody [A24A1]
F3647 Phospho-EGFR (Tyr992) Antibody [F20E14] EGFR (phospho Y992),Phospho-EGF Receptor (Tyr992)
F0257 Phospho-eIF2α (Ser51) Antibody [F15N7] EIF2S1 (phospho S51),Phospho-eIF2α (Ser51)
F1305 Phospho-eIF4B (Ser406) Antibody [B22D6]
F1674 Phospho-eIF4E (Ser209) Antibody [N23E19] eIF4E (phospho S209),Phospho-eIF4E (Ser209)
F0354 Phospho-eNOS (Ser1177) Antibody [N17K15] eNOS (phospho S1177),eNOS (pS1177),Phospho-eNOS (Ser1177)
F0595 Phospho-EphA2 (Ser897) Antibody [G4G3]
F0852 Phospho-EphA2 (Tyr588) Antibody [F13K2]
F3624 Phospho-ErbB2/ErbB4 (Y1248/1284) Antibody [K1P9]
F3950 Phospho-ErbB2/HER2 (Tyr1248) Antibody [F22D17]
F3606 Phospho-ErbB2/HER2 (Tyr877) Antibody [K16P14] ErbB2 / HER2 (phospho Y877),Phospho-HER2/ErbB2 (Tyr877)
F3001 Phospho-ErbB3/HER3 (Tyr1289) Antibody [P19F5] ErbB3 / HER3 (phospho Y1289),Phospho-HER3/ErbB3 (Tyr1289)
F1555 Phospho-Erk1 (T 202/Y 204)/Erk2 (T 185/Y 187) Antibody [G4M7] ERK1 (phospho T202 + Y204) + ERK2 (phospho T185 + Y187),Erk1 (pT202/pY204) + Erk2 (pT185/pY187),MAP Kinase, Activated (Diphosphorylated ERK-1&2),phospho-Erk1/2 (Thr202/Tyr204, Thr185/Tyr187)
F0502 Phospho-Erk1 (Tyr204)/Erk2 (Tyr187) Antibody [H17M24] Mitogen-activated protein kinase 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, ERK1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p44-ERK1, MAPK3, PRKM3, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, ERK2, PRKM1, PRKM2
F3945 Phospho-ERK1/ERK2 (T185/Y187) Antibody [G10H2]
F1716 Phospho-ERK1/ERK2 (T202/185) Antibody [G2D16]
F3358 Phospho-Estrogen Receptor α (Ser118) Antibody [L4E1] Estrogen Receptor alpha (phospho S118),Phospho-Estrogen Receptor α (Ser118)
F2876 Phospho-FAK (Tyr397) Antibody [G24K11] FAK (phospho Y397),FAK (Tyr397),p-FAK,Phospho-FAK (Tyr397)
F0647 Phospho-FGF Receptor (Tyr653/654) Antibody [F13P7] FGFR1 (phospho Y653),Phospho-FGF Receptor (Tyr653/654),Phospho-FGF Receptor 1 (Tyr653/654)
F4228 Phospho-FGF Receptor 1 (Tyr653/654) Antibody [P6D11]
F2747 Phospho-FGFR3 (Tyr724) Antibody [K24F17]
F1462 Phospho-FLT3 (Tyr589/591) Antibody [K5L11]
F0800 Phospho-FoxO1 (Ser256) Antibody [E12L24] FOXO1A (phospho S256),Phospho-FoxO1 (Ser256)
F3556 Phospho-FoxO1 (T24)/FoxO3a (T32) Antibody [M8K9]
F1155 Phospho-FoxO3A (Ser253) Antibody [C5A15] FOXO3A (phospho S253),Phospho-FoxO3a (Ser253)
F0902 Phospho-FoxO3a (Ser413) Antibody [A11H11]
F0799 Phospho-FRA1 (Ser265) Antibody [N10P17]
F3694 Phospho-Glucose Transporter GLUT4 (Ser488) Antibody [A20E7]
F2661 Phospho-Glycogen Synthase (Ser 641) Antibody [D7F20]
F2962 Phospho-Glycogen Synthase 1 (Ser641) Antibody [E2C19]
F0464 Phospho-GSK-3 (Ser21) Antibody [M22B5] GSK3 alpha (phospho S21),Phospho-GSK-3α (Ser21)
F0497 Phospho-GSK-3α/β (Ser21/9) Antibody [M19M24] Glycogen synthase kinase-3 alpha, GSK-3 alpha, Glycogen synthase kinase-3 beta, GSK-3α, GSK-3 beta, GSK-3β, GSK3A, GSK3B, GSK3, Serine/threonine-protein kinase GSK3B
F0496 Phospho-GSK-3α/β (Ser21/9) Antibody [N3H2]
F0299 Phospho-GSK-3β (Ser9) Antibody [G1H24] GSK3B (phospho S9),p-GSK3 beta,Phospho-GSK-3-beta (Ser9),Phospho-GSK-3β (Ser9)
F4124 Phospho-GSK-3β (Ser9) Antibody [G6H5]
F0396 Phospho-HDAC4 (S246)/5 (S259)/7 (S155) Antibody [H5N6]
F3397 Phospho-HDAC4/5/7 (Ser246/259/155) Antibody [J21N6]
F0853 Phospho-HER2/ErbB2 (Tyr1196) Antibody [L1F9]
F4155 Phospho-HER2/ErbB2 (Tyr1221/1222) Antibody [N18K6]
F0245 Phospho-HER2/ErbB2 (Tyr1221/1222) Antibody [P19C10] ErbB2 / HER2 (phospho Y1221 + Y1222),Phospho-HER2/ErbB2 (Tyr1221/1222)
F0802 Phospho-HER3/ErbB3 (Tyr1197) Antibody [F15P3]
F0019 Phospho-Histone H2A.X (Ser139) Antibody [E5F13] gamma H2A.X (phospho S139),gamma H2AX [p Ser139],Histone H2A.X (Ser139),p-Histone H2A.X(Ser 139),phospho-H2A.X (Ser139),phospho-Histone H2A.X (Ser139)
F1482 Phospho-Histone H2B (Ser14) Antibody [B13A9]
F0246 Phospho-Histone H3 (Ser10) Antibody [C5J11] Histone H3 (phospho S10),Phospho-Histone H3 (Ser10)
F2868 Phospho-Histone H3 (Ser10) Antibody [F5P3] Histone H3 (phospho S10),Phospho-Histone H3 (Ser10)
F2229 Phospho-Histone H3 (Ser10/ Thr11) Antibody [D13P19]
F4158 Phospho-Histone H3 (Thr3) Antibody [C4K12]
F2502 Phospho-Histone H3.3 (Ser31) Antibody [C20A16]
F1157 Phospho-HSF1 (Ser326) Antibody [G8N16]
F3688 Phospho-Hsp27 (Ser15) Antibody [D1B2] Hsp27 (phospho S15),Phospho-HSP27 (Ser15)
F0750 Phospho-HSP27 (Ser82) Antibody [J19L2] Hsp27 (phospho S82),Phospho-HSP27 (Ser82),Phospho-HSP27 (Ser82) II
F3764 Phospho-Hsp27 (Ser82) Antibody [M1P19] Hsp27 (phospho S82),Phospho-HSP27 (Ser82),Phospho-HSP27 (Ser82) II
F0247 Phospho-IGF-1R (Y1135/1136)/IR (Y1150/1151) Antibody [B2J21] Insulin-like growth factor 1 receptor, CD221, IGF1R, Insulin receptor, CD220, IR
F0398 Phospho-IGF-1R β (Tyr1135) Antibody [F22C20]
F1451 Phospho-IGF-1R β (Tyr980) Antibody [K22N4]
F3033 Phospho-IGF-1R β (Y1131)/IR β (Y1146) Antibody [J6K20] Phospho-IGF-I Receptor β (Tyr1131)/Insulin Receptor β (Tyr1146),Phospho-IGF-I Receptor β(Tyr1131)/Insulin Receptor β (Tyr1146)
F2237 Phospho-IKB α (Ser36) Antibody [B13N13]
F0448 Phospho-IKKα/β (S176/177) Antibody [L19G16]
F3837 Phospho-Insulin Receptor (Tyr1185) Antibody [D6L11]
F1383 Phospho-IP3 Receptor (Ser1756) Antibody [E15A22]
F0854 Phospho-IRAK4 (Thr345/Ser346) Antibody [G2K20]
F4013 Phospho-IRF3 (Ser386) Antibody [L20H23]
F1489 Phospho-IRS-1 (Ser302) Antibody [K1C11]
F1370 Phospho-IRS-1 (Ser318) Antibody [C11A11]
F0197 Phospho-IκBα (Ser32/36) Antibody [F24N7] IkB-alpha [p Ser32, p Ser36],Phospho-IκBα (Ser32/36)
F3783 Phospho-JAK1 (Tyr1034 + Tyr1035) Antibody [F22D15] JAK1 (phospho Y1034 + Y1035),Phospho-Jak1(Tyr1034/1035)
F2644 Phospho-JAK1 (Tyr1034/1035)/JAK2 (Tyr1007/1008) Antibody [L3G19]
F3912 Phospho-JNK (Thr183) Antibody [D9B9]
F1572 Phospho-JNK1/2/3 (T183/183/221) Antibody [D17M9]
F1573 Phospho-JNK1/2/3 (Tyr185/185/223) Antibody [G4D15]
F3444 Phospho-KAP1 (Ser824) Antibody [M4J16] KAP1 (phospho S824),KAP1 [p Ser824],Phospho-KAP-1 (Ser824)
F1962 Phospho-Lamin A/C (Ser22) Antibody [D12F9]
F3064 Phospho-LAT (Tyr220) Antibody [L15N18]
F3598 Phospho-LAT(Tyr200) Antibody [B1B14]
F0344 Phospho-LATS1 (Thr1079) Antibody [F2E16]
F0399 Phospho-LKB1 (Ser428) Antibody [H12K23]
F1549 Phospho-LRRK2 (Ser935) Antibody [K11C19]
F3330 Phospho-LRRK2 (Ser955) Antibody [F1M24]
F3144 Phospho-Lyn (Tyr507) Antibody [E9D13] Lyn (phospho Y507),Phospho-Lyn (Tyr507)
F2837 Phospho-MARCKS (Ser158) Antibody [D19L10]
F1259 Phospho-MARCKS (Ser167/170) Antibody [A4H10]
F2984 Phospho-MCM2 (Ser40) Antibody [M14L21]
F3206 Phospho-MCM2 (Ser53) Antibody [N19A7]
F1094 Phospho-MEK1 (Ser298) Antibody [D18F23] MEK1 (phospho S298),Phospho-MEK1 (Ser298)
F4751 Phospho-MEK1 (Ser298) Antibody [L22P14]
F0345 Phospho-MEK1/2 (Ser217/221) Antibody [G6P21] Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK 2, ERK activator kinase 2, MAPK/ERK kinase 2, MAP2K2, MKK2, PRKMK2, Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, MKK1, ERK activator kinase 1 MAPK/ERK kinase 1, MAP2K1, PRKMK1
F0250 Phospho-MEK1/2 (Ser221) Antibody [E14F20]
F1377 Phospho-Met (Tyr1003) Antibody [A3E17]
F4617 Phospho-Met (Tyr1349) Antibody [D24L22]
F1043 Phospho-Met/c-Met (Tyr1349 ) Antibody [F18B11] Met (c-Met) (phospho Y1349),Phospho-Met (Tyr1349)
F0704 Phospho-MKK3/6 (S189/207) Antibody [G15K24] Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPKK 3, MEK 3, Stress-activated protein kinase kinase 2, SAPK kinase 2, SAPKK-2, SAPKK2, MAP2K3, PRKMK3, SKK2, MAP kinase kinase 6, MAPKK 6, MEK 6, SAPK kinase 3, SAPKK-3, SAPKK3, MAP2K6, PRKMK6, SKK3, Dual specificity mitogen-activated protein kinase kinase 6, Stress-activated protein kinase kinase 3
F3845 Phospho-Moesin (Thr558) Antibody [N2L9]
F0855 Phospho-MST1/2 (Thr183/180) Antibody [K6K3] MST1/MST2 (phospho T180 + T183),Phospho-MST1 (Thr183)/MST2 (Thr180)
F0158 Phospho-mTOR (Ser2448) Antibody [H1M6] mTOR (phospho S2448),Phospho-mTOR (Ser2448),p-mTOR
F2584 Phospho-mTOR (Ser2448) Antibody [P18P17] mTOR (phospho S2448),Phospho-mTOR (Ser2448),p-mTOR
F1578 Phospho-mTOR (Ser2481) Antibody [H20P20] mTOR (phospho S2481),Phospho-mTOR (Ser2481)
F1242 Phospho-Myosin Light Chain 2 (Thr18/Ser19) Antibody [C13P19]
F2860 Phospho-NAK/TBK1 (Ser172) Antibody [G18L12] NAK/TBK1 (phospho S172),Phospho-TBK1/NAK (Ser172)
F0450 Phospho-NDRG1 (Thr346) Antibody [B22E4]
F3665 Phospho-NEDD4-2 (Ser448) Antibody [D21H23] NEDD4-2 (phospho S448),Phospho-NEDD4L (Ser448)
F3646 Phospho-Nephrin (Tyr1176 + Tyr1193) Antibody [D21M18]
F3306 Phospho-Nephrin (Tyr1217) Antibody [L5D2]
F0400 Phospho-NF-κB p105 (Ser932) Antibody [H7P1]
F3499 Phospho-NF-κB p65 (Ser468) Antibody [G12A6]
F3512 Phospho-NF-κB p65 (Ser536) Antibody [G11D5] NF-kB p65 (phospho S536),Phospho-NFkB p65 (Ser536),Phospho-NF-κB p65 (Ser536),p-RELA/NFκB p65
F0155 Phospho-NF-κB p65 (Ser536) Antibody [M4C8] NF-kB p65 (phospho S536),Phospho-NFkB p65 (Ser536),Phospho-NF-κB p65 (Ser536),p-RELA/NFκB p65
F2394 Phospho-NMDAR2B (Ser1303) Antibody [G14F14]
F1552 Phospho-Nrf2 (Ser40) Antibody [N4G2]
F3443 Phospho-p130 (Ser672) Antibody [E21C6]
F1167 Phospho-p27 KIP 1 (Ser10) Antibody [D8F10] Phospho-p27 KIP 1 (Ser 10) Rabbit mAb detects endogenous levels of p27 KIP 1 only when phosphorylated at Ser10.
F0159 Phospho-p38 MAPK (Thr180/Tyr182) Antibody [M21L8] Mitogen-activated protein kinase 14 , MAP kinase 14, MAPK 14, CSAID-binding protein, CSBP,MAP kinase MXI2, MAX-interacting protein 2, MAP kinase p38 alpha, MAP kinase p38 α, SAPK2a, MAP kinase 12, MAPK 12, ERK-6, MAP kinase p38 gamma, Stress-activated protein kinase 3, MAPK12, SAPK3, MAP kinase 11; MAPK 11, MAP kinase p38 beta, p38b, SAPK2b, p38-2, MAPK11, PRKM11, SAPK2, SAPK2B, MAP kinase 13, MAPK 13, MAP kinase p38 delta, Stress-activated protein kinase 4, MAPK13, PRKM13, SAPK4, MAP kinase p38 δ, MAP kinase p38 γ
F4107 Phospho-p38 MAPK (Tyr182) Antibody [H7F4]
F0007 Phospho-p44/42 MAPK (Erk1/2) (T202/Y204) Antibody [D13L13] Mitogen-activated protein kinase 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, ERK1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, Microtubule-associated protein 2 kinase, p44-ERK1, MAPK3, PRKM3, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, ERK2, PRKM1, PRKM2
F4120 Phospho-p53 (Ser15) Antibody [C9F23]
F0355 Phospho-p53 (Ser15) Antibody [K22F18] p53 (phospho S15),Phospho-p53 (Ser15)
F2377 Phospho-p53 (Ser20) Antibody [J22P21] p53 (phospho S20),Phospho-p53 (Ser20)
F2366 Phospho-p53 (Ser37) Antibody [P9G5] p53 (phospho S37),Phospho-p53 (Ser37),TP53 (phospho S37)
F2931 Phospho-p53 (Ser392) Antibody [E21F8] p53 (phospho S392),Phospho-p53 (Ser392)
F3927 Phospho-p53 (Ser9) Antibody [G23F10]
F2907 Phospho-P70 S6 Kinase β/SRK (Ser371) Antibody [A17F8] P70 S6 Kinase beta/SRK (phospho S371)
F2333 Phospho-p70 S6K (Thr421/Ser424) Antibody [E5J12] p70 S6K phospho Thr421 Ser424,Phospho-p70 S6 Kinase (Thr421/Ser424)
F0557 Phospho-p90 RSK (Thr359) Antibody [M10J19] Phospho-p90RSK (Thr359),RSK1 p90 (phospho T359)
F0503 Phospho-p90RSK (Ser380) Antibody [F5E5] Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, S6K-α-3, 90 kDa ribosomal protein S6 kinase 3, p90-RSK 3, p90RSK3, Insulin-stimulated protein kinase 1 , ISPK-1, MAP kinase-activated protein kinase 1b, MAPK-activated protein kinase 1b, MAPKAP kinase 1b, MAPKAPK-1b, Ribosomal S6 kinase 2, RSK-2, p90RSK2, RPS6KA3, ISPK1, MAPKAPK1B, RSK2, Ribosomal protein S6 kinase alpha-2, S6K-alpha-2, S6K-α-2, 90 kDa ribosomal protein S6 kinase 2, p90-RSK 2, p90RSK2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, Ribosomal S6 kinase 3, RSK-3, RPS6KA2, MAPKAPK1C, RSK3, S6K-alpha-1, p90-RSK 1, p90RSK1, p90S6K, MAPKAP kinase 1a, MAPKAPK-1a, RSK-1, RPS6KA1, MAPKAPK1A, RSK1, Ribosomal S6 kinase 1
F2117 Phospho-PAK1/2/3 (Ser144/141/154) Antibody [A5J4]
F0804 Phospho-PDGF Receptor β (Tyr1009) Antibody [G5H10]
F1260 Phospho-PDGF Receptor β (Tyr1021) Antibody [M20P20]
F1500 Phospho-PDGF Receptor β (Tyr740) Antibody [M18D12]
F1497 Phospho-PDGF Receptor β (Tyr771) Antibody [C22C4]
F1658 Phospho-PDHA1 (Ser293) Antibody [L15N22] PDHA1 (phospho S293),Phospho-Pyruvate Dehydrogenase α1 (Ser293),Pyruvate Dehydrogenase E1-alpha subunit [p Ser293]
F0401 Phospho-PDK1 (Ser241) Antibody [K13M24]
F0346 Phospho-PERK (Thr980) Antibody [E16F3]
F3893 Phospho-PERK (Thr982) Antibody [A3P5]
F0903 Phospho-PFKFB2 (Ser483) Antibody [A5G21]
F3884 Phospho-Phospholipase Cγ1/PLC-γ-1 (Tyr783) Antibody [J4J15]
F4613 Phospho-PKA C (Thr197) Antibody [L13C4]
F1206 Phospho-PKA α/β/γ (catalytic subunit) (T197) Antibody [F5K1] Phospho-PKA C (Thr197),PKA alpha/beta/gamma (catalytic subunit) (phospho T197)
F2119 Phospho-PKAR2/PKR2 (Ser99) Antibody [F21N14]
F3551 Phospho-PKC (pan) (βII Ser660) Antibody [G6B3]
F0651 Phospho-PKC (pan) (ζ Thr410) Antibody [F2F5] Protein kinase C beta type, Protein kinase C alpha type, Protein kinase C zeta type, Protein kinase C eta type, Protein kinase C delta type, Protein kinase C theta type, Protein kinase C epsilon type, Protein kinase C gamma type, Protein kinase C iota type, PKC-B, PKC-beta, PKC β, PRKCB, PKCB, PRKCB1, PKC-A, PKC-alpha, PKC α, PRKCA, PKCA, PRKACA, nPKC-zeta, PRKCZ, PKC2, PKC ζ, PKC η, PKC-L, nPKC-eta, PRKCH, PKCL, PRKCL, PKC δ, nPKC-delta, PRKCD, PKCD, PKC θ, nPKC-theta, PRKCQ, PRKCT, PKC ε, nPKC-epsilon, PRKCE, PKCE, PKC-gamma, PKC γ, PRKCG, PKCG, PKC ι, nPKC-iota, PRKCI, DXS1179E, Atypical protein kinase C-lambda/iota, PRKC-lambda/iota, aPKC-lambda/iota, Tyrosine-protein kinase PRKCD, Sphingosine-dependent protein kinase-1
F2745 Phospho-PKC (Ser660) Antibody [J16E1]
F2615 Phospho-PKC (Thr514) Antibody [B16L4]
F2482 Phospho-PKC α (Ser657) Antibody [M1L12]
F2561 Phospho-PKC α (Thr497) Antibody [A17J8]
F2914 Phospho-PKC α (Thr638) Antibody [E6G7]
F3958 Phospho-PKC δ (Tyr311) Antibody [P4C22]
F3045 Phospho-PKCδ (Thr505) Antibody [P3G5]
F2335 Phospho-PKCθ/PRKCQ (Thr538) Antibody [D2M12] Phospho-PKCθ (Thr538),PKC theta/PRKCQ (phospho T538)
F1597 Phospho-PKR (Thr446) Antibody [K16N13]
F2372 Phospho-PKR (Thr451) Antibody [C9J9]
F0705 Phospho-PLCγ1 (Ser1248) Antibody [E9E19]
F0752 Phospho-PLCγ1 (Tyr783) Antibody [C6N17] Phospholipase C gamma 1/PLC-gamma-1 (phospho Y783),Phospho-PLCγ1 (Tyr783)
F2595 Phospho-PPP1A/PPP1CA (Thr320) Antibody [J22F13] Phospho-PP1α (Thr320),PPP1A/PPP1CA (phospho T320)
F4154 Phospho-PRAS40 (Thr246) Antibody [P11G2]
F0252 Phospho-PRAS40 (Thr246) Antibody [P21B22]
F0499 Phospho-PTEN (Ser380/Thr382/383) Antibody [K19C17] Phospho-PTEN (Ser380),Phospho-PTEN (Ser380/Thr382/383),PTEN (phospho S380)
F2618 Phospho-PTEN (Thr366) Antibody [A11K14]
F1636 Phospho-RAB10 (Thr73) Antibody [M19N14]
F1517 Phospho-Rb (Ser608) Antibody [A17K22] Phospho-Rb (Ser608),Rb (phospho S608)
F3348 Phospho-Rb (Ser780) Antibody [C10L19]
F0501 Phospho-Rb (Ser780) Antibody [L13P18] Phospho-Rb (Ser780),Progesterone Receptor,Rb (phospho S780)
F0302 Phospho-Rb (Ser807/811) Antibody [P5B14]
F3609 Phospho-Rb (Thr373) Antibody [F9H20]
F3424 Phospho-Rb (Thr826) Antibody [F21F15]
F0533 Phospho-Rictor (Thr1135) Antibody [P16B3]
F0500 Phospho-RIP (Ser166) Antibody [C18P2]
F3700 Phospho-RKIP (Ser153) Antibody [J22F24]
F2949 Phospho-RNA Pol II CTD (Ser5) Antibody [E1J24] Phospho-Rpb1 CTD (Ser5),RNA polymerase II CTD repeat YSPTSPS (phospho S5),RNA polymerase II subunit B1 (phospho-CTD Ser 5)
F0023 Phospho-RNA pol II CTD (Ser5) Antibody [F13E6] Phospho-Rpb1 CTD (Ser5),RNA polymerase II CTD repeat YSPTSPS (phospho S5),RNA polymerase II subunit B1 (phospho-CTD Ser 5)
F3793 Phospho-RNA Pol II CTD repeat YSPTSPS (S2) Antibody [C9K19] Phospho-Rpb1 CTD (Ser2),RNA polymerase II CTD repeat YSPTSPS (phospho S2),RNA polymerase II subunit B1 (phospho CTD Ser-2)
F2375 Phospho-RPA32/RPA2 (Thr21) Antibody [H20D7]
F0805 Phospho-Rpb1 CTD (Ser2) Antibody [L19G24] Phospho-Rpb1 CTD (Ser2),RNA polymerase II CTD repeat YSPTSPS (phospho S2),RNA polymerase II subunit B1 (phospho CTD Ser-2)
F1261 Phospho-Rpb1 CTD (Ser7) Antibody [C17G21] Phospho-Rpb1 CTD (Ser7),RNA polymerase II subunit B1 (phospho-CTD Ser 7)
F2728 Phospho-RSK1 p90 (Ser380) Antibody [G13M8]
F2334 Phospho-RSK1 p90 (T359/S363) Antibody [P19K15] Phospho-p90RSK (Thr359/Ser363),RSK1 p90 (phospho T359 + S363)
F4044 Phospho-RSK1 p90 (Thr359) Antibody [L24F14]
F0904 Phospho-RSK2 (Ser227) Antibody [F3D15] S6K-alpha-3, S6K-α-3, p90-RSK 3; p90RSK3, ISPK-1, MAPKAP kinase 1b, MAPKAPK-1b, RSK-2, p90RSK2, RPS6KA3, ISPK1, MAPKAPK1B, RSK2
F0198 Phospho-S6 Ribosomal Protein (S235/236) Antibody [G7G11] Phospho-S6 Ribosomal Protein (Ser235/236),RPS6 (phospho S235 + S236)
F3530 Phospho-S6 Ribosomal Protein (S235/236) Antibody [H18E15] Phospho-S6 Ribosomal Protein (Ser235/236),RPS6 (phospho S235 + S236)
F0303 Phospho-S6 Ribosomal Protein (Ser240/244) Antibody [H21K17] Phospho-S6 Ribosomal Protein (Ser240/244),RPS6 (phospho S240 + S244)
F1484 Phospho-SAMHD1 (Thr592) Antibody [K24L13]
F0600 Phospho-SEK1/MKK4 (Ser257) Antibody [C11A7]
F1300 Phospho-SGK1 (Ser78) Antibody [E23F7]
F0706 Phospho-SHP-1 (Tyr564) Antibody [N2F10]
F1301 Phospho-SHP-2 (Tyr580) Antibody [M15P16]
F2201 Phospho-SHP2 (Tyr542) Antibody [J17K6] Phospho-SHP-2 (Tyr542),SHP2 (phospho Y542)
F3052 Phospho-SLP-76 (Ser376) Antibody [K18E5]
F2633 Phospho-Smad1 (Ser206) Antibody [D10B24]
F0348 Phospho-Smad1/5 (Ser463/465) Antibody [H6D11]
F0347 Phospho-Smad1/5/9 (S463/465, S463/465, S465/467) Antibody [L11J17] Phospho-Smad1 (Ser463/465)/ Smad5 (Ser463/465)/ Smad9 (Ser465/467),SMAD1 + SMAD5 + SMAD9 (phospho S463 + S465 + S467)
F2875 Phospho-Smad1/5/9 (S463/465/467) Antibody [K12G16] Phospho-Smad1 (Ser463/465)/ Smad5 (Ser463/465)/ Smad9 (Ser465/467),SMAD1 + SMAD5 + SMAD9 (phospho S463 + S465 + S467)
F3553 Phospho-SMAD2 (Ser245/250/255) Antibody [H4M3]
F3450 Phospho-Smad2 (Ser250) Antibody [J3P10]
F1689 Phospho-Smad2 (Ser255) Antibody [H13B7]
F3740 Phospho-Smad2 (Ser467) Antibody [P3A22]
F2846 Phospho-Smad3 (Ser423/Ser425) Antibody [L3N2] Phospho-Smad3 (Ser423/425),Smad3 (phospho S423 + S425), Smad5 (463/465), Smad1 (Ser 463/465), Smad2 (Ser 465/467)d5 (Se
F1378 Phospho-SMC1 (Ser957) Antibody [L22G18]
F1460 Phospho-SQSTM1/p62 (Ser349) Antibody [C5L4] Phospho-SQSTM1/p62 (Ser349),SQSTM1 / p62 (phospho S349)
F0955 Phospho-SQSTM1/p62 (Ser403) Antibody [B10J4]
F0906 Phospho-Src (Ser17) Antibody [A23D16]
F2912 Phospho-Src (Tyr529) Antibody [D13P6]
F4136 Phospho-Src Family (Tyr416) Antibody [D13C8]
F0304 Phospho-Src Family (Tyr416) Antibody [H4N15] Tyrosine-protein kinase Yes, Proto-oncogene c-Yes, p61-Yes, YES1, YES, Tyrosine-protein kinase Lyn, Lck/Yes-related novel protein tyrosine kinase, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, p53Lyn, p56Lyn, LYN, JTK8, Tyrosine-protein kinase Lck, LSK, Lymphocyte cell-specific protein-tyrosine kinase, Protein YT16, Proto-oncogene Lck, T cell-specific protein-tyrosine kinase, p56-LCK, Tyrosine-protein kinase HCK, Hematopoietic cell kinase, Hemopoietic cell kinase, p59-HCK/p60-HCK, p59Hck, p61Hck, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, p60-Src, SRC, SRC1, Tyrosine-protein kinase Fyn, Proto-oncogene Syn, Proto-oncogene c-Fyn, SLK, p59-Fyn
F1649 Phospho-SRC Family (Tyr418) Antibody [H7L14]
F3253 Phospho-STAT1 (Ser727) Antibody [C14E15] Phospho-Stat1 (Ser727),STAT1 (phospho S727)
F2358 Phospho-STAT1 (Ser727) Antibody [F23C16] Phospho-Stat1 (Ser727),STAT1 (phospho S727)
F0451 Phospho-STAT1 (Ser727) Antibody [K4E23] Phospho-Stat1 (Ser727),STAT1 (phospho S727)
F0199 Phospho-STAT1 (Tyr701) Antibody [N19D1] Phospho-Stat1 (Tyr701),p-Stat1,STAT1 (phospho Y701)
F0554 Phospho-STAT2 (Tyr690) Antibody [G1A15] Phospho-Stat2 (Tyr690),STAT2 (phospho Y690)
F1212 Phospho-STAT3 (Ser727) Antibody [B8F21] Phospho-Stat3 (Ser727),STAT3 (phospho S727)
F4695 Phospho-STAT3 (Ser727) Antibody [J17G14]
F0157 Phospho-STAT3 (Tyr705) Antibody [B17F7] Phospho-Stat3 (Tyr705),p-Stat3,STAT3 (phospho Y705)
F4146 Phospho-Stat5 (Tyr694) Antibody [L6J15]
F0555 Phospho-STAT6 (Tyr641) Antibody [A16N6] Phospho-Stat6 (Tyr641),STAT6 (phospho Y641)
F4042 Phospho-STAT6 (Tyr641) Antibody [G7E12]
F1396 Phospho-Stathmin (Ser38) Antibody [L1J22]
F3319 Phospho-Syk (Tyr323) Antibody [G1N3]
F3953 Phospho-Synapsin I (Ser553) Antibody [F18C24]
F1303 Phospho-Synapsin-1 (Ser605) Antibody [M6M7]
F2613 Phospho-TAK1 (Ser439) Antibody [F17C11]
F0402 Phospho-TAK1 (Thr184/187) Antibody [G4C5]
F2614 Phospho-Tau (Ser199) Antibody [F2N9] Phospho-Tau (Ser199),Tau (phospho S199)
F4113 Phospho-Tau (Ser202) Antibody [L24P20]
F0059 Phospho-Tau (Ser202/ Thr205) Antibody [C18J10] Phospho-Tau (Ser202, Thr205),Phospho-Tau (Ser202/Thr205),Tau (phospho S202 + T205)
F3533 Phospho-Tau (Ser202/Thr205) Antibody [M2L8] Phospho-Tau (Ser202, Thr205),Phospho-Tau (Ser202/Thr205),Tau (phospho S202 + T205)
F2775 Phospho-Tau (Ser214) Antibody [M8H2] Phospho-Tau (Ser214),Tau (phospho S214)
F3922 Phospho-Tau (Ser262) Antibody [N15P23]
F1117 Phospho-Tau (Ser396) Antibody [E23L9] Phospho-Tau (Ser396),Tau (phospho S396)
F3592 Phospho-Tau (Ser396) Antibody [F10A13] Phospho-Tau (Ser396),Tau (phospho S396)
F2593 Phospho-Tau (Ser404) Antibody [F11H2] Phospho-Tau (Ser404),Tau (phospho S404)
F3020 Phospho-Tau (Ser416) Antibody [H22B7] Phospho-Tau (Ser416),Tau (phospho S416)
F2605 Phospho-Tau (Ser422) Antibody [L19H1]
F2389 Phospho-Tau (Thr231) Antibody [G20J9] Phospho-Tau (Thr231),Tau (phospho T231)
F0255 Phospho-TBK1/NAK (Ser172) Antibody [H16A23] NAK/TBK1 (phospho S172),Phospho-TBK1/NAK (Ser172)
F1474 Phospho-TFEB (Ser211) Antibody [N21G19]
F1348 Phospho-TRAF2 (Ser11) Antibody [L10C17]
F0403 Phospho-TrkA (Tyr674/675)/TrkB (Tyr706/707) Antibody [K13K11]
F0652 Phospho-TrkA (Y785)/TrkB (Y816) Antibody [G6J11]
F1948 Phospho-Tuberin/TSC2 (Ser1387) Antibody [B6D9]
F0956 Phospho-Tyk2 (Tyr1054/1055) Antibody [H3E15]
F1476 Phospho-Ubiquitin (Ser65) Antibody [C22F3]
F0305 Phospho-ULK1 (Ser555) Antibody [N1G15] Phospho-ULK1 (Ser555),ULK1 (phospho S555)
F0351 Phospho-ULK1 (Ser757) Antibody [A12P8]
F1397 Phospho-VASP (Ser157) Antibody [G6G22] Phospho-VASP (Ser157),VASP (phospho S157)
F2659 Phospho-VASP (Ser239) Antibody [N1M20]
F4139 Phospho-VEGF Receptor 2 (Tyr1175) Antibody [M10N15]
F0256 Phospho-VEGF Receptor 2 (Tyr1175) Antibody [M9C2] Phospho-VEGF Receptor 2 (Tyr1175),VEGF Receptor 2 (phospho Y1175)
F3649 Phospho-Vimentin (Ser39) Antibody [B14E20]
F0602 Phospho-Wee1 (Ser642) Antibody [P3A10]
F0352 Phospho-YAP (Ser127) Antibody [K8E8] Phospho-YAP (Ser127),YAP1 (phospho S127)
F0753 Phospho-YAP (Ser397) Antibody [B23M8]
F0603 Phospho-YB1 (Ser102) Antibody [D17A16]
F0556 Phospho-Zap-70 (Tyr319)/Syk (Tyr352) Antibody [L15L21] Tyrosine-protein kinase ZAP-70, 70 kDa zeta-chain associated protein, Syk-related tyrosine kinase, ZAP70, SRK, Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk, SYK
F1478 Phospho-Zyxin (Ser142/143) Antibody [L24L6]
F2121 Phospho-β Arrestin 1 (Ser412) Antibody [B21D5]
F3241 Phospho-β Catenin (Ser675) Antibody [D16B23]
F0908 Phospho-β-Arrestin 1 (Ser412) Antibody [C17A12]
F0494 Phospho-β-Catenin (Ser552) Antibody [K9A16]
F0297 Phospho-β-Catenin (Ser675) Antibody [G12L16]
S3349 Phosphocholine chloride calcium salt tetrahydrate

Phosphocholine (Phosphorylcholine) chloride calcium salt tetrahydrate is an active endogenous metabolite.

F1349 Phospholamban Antibody [C9L22]
S3356 Phosphonoacetic acid

Phosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.

S7382 Phosphoramidon Disodium Salt Phosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool. Phosphoramidon inhibited ECE, NEP, and ACE activities with IC50 values of 3.5 μM, 0.034 μM, and 78 μM, respectively.
E7023 Phosphorylcholine chloride Phosphorylcholine chloride (Phosphocholine chloride) is a zwitterionic small molecule that forms the hydrophilic head group of major eukaryotic membrane phospholipids and is also found on the surface of commensal or pathogenic bacteria associated with eukaryotes. It exhibits immunomodulatory properties and commonly used in biomaterial coatings to reduce protein adsorption, prevent unwanted cell adhesion, and improve implant biocompatibility.
F2798 PHOX2B C-terminal Antibody [C18L18]
S9913 PHPS1

PHPS1 (PTP Inhibitor V), a potent and cell-permeable inhibitor, is specific for Shp2 with Ki value of 0.73 μM.

S1556 PHT-427 PHT-427 (CS-0223) is a dual Akt and PDPK1 inhibitor (high affinity binding for the PH domains of Akt and PDPK1) with Ki of 2.7 μM and 5.2 μM, respectively.
S6215 Phthalic acid Phthalic acid (1,2-Benzenedioic acid) is an aromatic dicarboxylic acid. It is a human xenobiotic metabolite.
S5700 Phthalylsulfathiazole Phthalylsulfathiazole (Sulfathalidine) is a broad-spectrum antimicrobial that can treat different types of infections including intestinal.
S3793 Phytic acid Phytic acid (Inositol polyphosphate, Inositol hexakisphosphate) is the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It can act as a cofactor in DNA repair by nonhomologous end-joining. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.
S3326 Phytic acid dipotassium salt

Phytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)), an endogenous metabolite in rice grain extract and digest, inhibits β-secretase 1 (BACE1) with IC50 of approximately 0.25 μM.

S5121 Phytol Phytol (Trans-Phytol), a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects. It is a specific activator of PPARα.
S9218 Phytolaccagenin Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phtolaccae.
S5150 Phytosterols Phytosterols, also called plant sterols or stanol esters, are specialized compounds found in plants that are structurally similar to cholesterol found in humans.
F4899 PI 3 Kinase catalytic subunit α/PIK3CA Antibody [C16C18]
F2032 PI 3 Kinase p85 β Antibody [D1J6]
S1038 PI-103 PI-103 is a multi-targeted PI3K inhibitor for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM in cell-free assays, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. PI-103 induces apoptosis in murine T-cell Lymphoma.
E2374 PI-273 PI-273, the first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0.47 μM, can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis.
F1515 PI3 Kinase Class II α Antibody [B2P18] PI 3-kinase C2α,PI3 Kinase Class II α
F1398 PI3 Kinase p101 Antibody [H23D19]
F2645 PI3 Kinase p110 δ Antibody [H17B15] PI 3 Kinase p110 delta,PI 3-kinase p110δ,PI3 Kinase p110 δ
F0293 PI3 Kinase p110α Antibody [P8E2] PI 3 Kinase catalytic subunit alpha/PIK3CA,PI3 Kinase p110α
F1205 PI3 Kinase p110β Antibody [A2M11] PI3 Kinase p110 beta,PI3 Kinase p110β
F4196 PI3 Kinase p110β Antibody [D23E3]
F0643 PI3 Kinase p110γ Antibody [L1P11] PI 3 Kinase catalytic subunit gamma/PI3K-gamma,PI3 Kinase p110γ
F0850 PI3 Kinase p55 Antibody [N13P24]
F0294 PI3 Kinase p85 Antibody [A5E17] PI3 Kinase,PI3 Kinase p85
F1720 PI3 Kinase p85α Antibody [K4G2] PI 3 Kinase p85 alpha,PI 3-kinase p85α,PI3 Kinase p85α
F4012 PI3 Kinase p85α Antibody [L7D21]
L2800 PI3K/Akt Inhibitor Library A unique collection of 355 small molecule inhibitors used for PI3K/Akt/mTOR pathway research.
E4683 PI3K/AKT-IN-1 PI3K/AKT-IN-1 is a dual-acting inhibitor of PI3K/AKT pathway with an IC50 of 6.99 µM, 4.01 µM, and 3.36 µM, for PI3Kδ, PI3Kγ and AKT-1 respectively. It also induces S-phase cell cycle arrest, caspase-3-dependent apoptosis, exhibiting strong potential against breast cancer and leukemia.
E5889 PI3K/Akt/mTOR-IN-2 PI3K/Akt/mTOR-IN-2 is a specific inhibitor of the PI3K/Akt/mTOR signaling pathway. It exhibits an effective anti-cancer activity with IC50 value of 2.29 μM and can induce cancer cell cycle arrest and apoptosis.
E2375 PI3K/mTOR Inhibitor-2 PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with antitumor activity.
E2981 PI4KIIIbeta-IN-10 PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ with an IC50 of 3.6 nM. It also exhibits weak inhibition of PI3KC2γ, PI3Kα, and PI4KIIIα, and <20% inhibition at concentrations up to 20 µM for PI4K2α, PI4K2β, and PI3Kβ.
F4694 PIAS1 Antibody [J24P15]
F1048 PIAS1 Antibody [L5H9]
F1516 PIAS3 Antibody [G3P18]
F0897 PIAS4 Antibody [D22D4] E3 SUMO-protein ligase PIAS4/PIASy,PIAS4
S9641 Pibrentasvir (ABT-530) Pibrentasvir (ABT-530) is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50 ranging from 1.4 pM to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6.
S3026 Piceatannol Piceatannol, a natural stilbene, is a selective Syk inhibitor and ~10-fold selectivity versus Lyn.
S9138 Picfeltarraenin IA Picfeltarraenin IA is an AChE inhibitior, and an potential PI3K and EGFR inhibitor. It also acts as an inhibitor on both the classical and alternative pathways of the complement system.
S3246 Picfeltarraenin IB Picfeltarraenin IB, a cucurbitacin glycoside isolated from Picriafel-terrae, is an inhibitor of acetylcholinesterase (AChE). Picfeltarraenin IB can be used for the treatment of herpes infections, cancer and inflammation.
E4648 Pico145 Pico145(HC-608) is a selective inhibitor of TRPC1/4/5 channels. It inhibits (−)-englerin A-activated TRPC4/TRPC5 channels, with IC50 values of 0.349 and 1.3 nM, respectively. It exhibits no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
S4710 Picolinamide Picolinamide (2-Pyridinecarboxamide, Picolinoylamide, 2-Carbamoylpyridine) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
S6249 Picolinic acid (PCL 016) Picolinic acid (PCL 016) is a pyridine carboxylate metabolite of tryptophan and acts as an anti-infective and immunomodulator. It acts by binding with the zinc associated with zinc finger proteins to alter their structure and inhibit function.
E0242 Picrocrocin Picrocrocin, the chemical most responsible for the bitter taste of saffron, is isolated from saffron and inhibits proliferation of cancer cells.
S7668 Picropodophyllin (AXL1717) Picropodophyllin (PPP, AXL1717) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR(FGF-R, PDGF-R, OR EGF-R). Picropodophyllin (PPP) induces apoptosis with antineoplastic activity.
S3787 Picroside I Picroside I (6'-Cinnamoylcatalpol), an iridoid glycoside, is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B.
S3765 Picroside II Picroside II (6-Vanilloylcatalpol, Vanilloyl catalpol) is the main active ingredient in iridoid glycosides, which is the principal component of Picrorrhiza kurroa Royle. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.
S6100 Picrotoxin Picrotoxin (Picrotin, Cocculin, Cocculus, NSC 403139), a plant alkaloid, is a non-competitive antagonist of neuronal GABA and glycine receptors.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S1065 Pictilisib (GDC-0941) Pictilisib (GDC-0941, RG7321) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM in cell-free assays, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Pictilisib (GDC-0941) induces autophagy and apoptosis. Phase 2.
S3106 Pidotimod Pidotimod(Pidotomod) is an immunostimulant.
S2929 Pifithrin-α (PFTα) Hhydrobromide Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes. Pifithrin-α is also a potent agonist of the aryl hydrocarbon receptor (AhR).
E2943 Pifithrin-β Pifithrin-β (PFT β hydrobromide; Cyclic Pifithrin-α hydrobromide) is a potent inhibitor of p53 with an IC50 of 23 μM and is regarded as a lead compound for cancer and neurodegenerative disease therapy.
S2930 Pifithrin-μ Pifithrin-μ (NSC 303580, PFTμ, 2-Phenylethynesulfonamide) is a specific p53 inhibitor by reducing its affinity to Bcl-xL and Bcl-2, and also inhibits HSP70 function and autophagy.
E2823 PIK-108 PIK-108 is a non-ATP competitive, allosteric p110β/p110δ selective inhibitor.
S1205 PIK-75 HCl PIK-75 HCl is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
S1489 PIK-93 PIK-93 is the first potent, synthetic PI4K (PI4KIIIβ) inhibitor with IC50 of 19 nM; shown to inhibit PI3Kα with IC50 of 39 nM.
S7683 PIK-III PIK-III (VPS34-IN2), which is a selective inhibitor of ​VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. The IC50 values for VPS34 and PI(3)Kδ are 0.018 μM and 1.2 μM respectively.
S5363 Pikamilone Pikamilone is a drug having a central (vegetotropic and vascular) and peripheral (vasodilating) mechanisms of action.
S7645 Pilaralisib (XL147) Pilaralisib (XL147) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. Phase 1/2.
E7001 Pilocarpine Pilocarpine is a non-selective agonist of muscarinic acetylcholine receptor (mAChR), commonly used to treat xerostomia and glaucoma. It modulates the electrical properties of heart cells, likely by activating a potassium (K+) current mediated by M3 receptors.
S4231 Pilocarpine HCl Pilocarpine HCl (NSC 5746) is a selective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy.
F0857 Pim-1 Antibody [C2K23]
F4689 Pim-1 Antibody [J10P8]
F0754 Pim-2 Antibody [J4J24] PIM2,Pim-2
F0808 Pim-3 Antibody [H6L6]
F3887 PIM2 Antibody [L18N23]
S7985 PIM447 (LGH447) Hydrochloride PIM447 (LGH447) Hydrochloride is a novel pan-PIM kinase inhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively. It also inhibits GSK3β, PKN1, and PKCτ, but at a significantly lower potency with IC50 between 1 and 5 μM (>105-fold differential relative to the Ki on PIMs). PIM447 induces apoptosis.
S1475 Pimasertib (AS-703026) Pimasertib (AS-703026, MSC1936369B, SAR 245509) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. Phase 2.
S8183 Pimavanserin tartrate Pimavanserin tartrate(ACP-103) is a potent and selective serotonin 5-HT2A inverse agonist with pIC50 of 8.73, used to treat psychosis associated with Parkinson’s disease.
S5004 Pimecrolimus Pimecrolimus (Elidel,ASM 981,SDZ-ASM 981) is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12 (FKBP-12); a calcineurin inhibitor.
S3145 Pimelic acid

Pimelic acid (Heptanedioic acid, 1,5-Pentanedicarboxylic acid, 1,7-Heptanedioic acid) originating from fatty acid synthesis pathway is a bona fide precursor of biotin in B. subtilis.

E4862 Pimethixene Pimethixene(Calmixen, Pimetixene) is a highly potent and non-selective antagonist of the 5-HT2B receptor, with a pKi of 10.44. It also functions as an antihistamine and anticholinergic agent, and is a highly potent multi-target antagonist with antagonistic effects on multiple receptors.
S3913 Pimethixene maleate Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.22, 10.44, 8.42, 7.63, < 5, 7.30, 7.28, 7.61, 6.37, 8.19, 7.54, 10.14, 8.61 and 9.38, respectively.
E1727 Pimicotinib Pimicotinib (ABSK021) is an orally bioavailable inhibitor of colony stimulating factor 1 receptor (CSF1R). It enhances antitumor T-cell immune responses and inhibits the proliferation of tumor cells having potential immunomodulatory and antineoplastic activities.
S1550 Pimobendan Pimobendan (UD-CG 115 BS) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.
S9919 Pimonidazole Pimonidazole (Ro 03-8799) is a novel hypoxia marker used for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma.
S4358 Pimozide Pimozide (Orap, R6238) is an antagonist of Dopamine Receptors with Ki of 0.83 nM, 3.0 nM and 6600 nM for dopamine D3, D2 and D1 receptors, respectively. Pimozide also exhibits binding affinity at 5-HT1A and α1-adrenoceptor with Ki of 310 nM and 39 nM, respectively. Pimozide is an antipsychotic drug with anti-tumor activity and suppresses STAT3 and STAT5 activity.
S6893 PIN1 inhibitor API-1 PIN1 inhibitor API-1 is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor with IC50 of 72.3 nM. PIN1 inhibitor API-1 targets Pin1 peptidyl-prolyl isomerase domain and inhibits Pin1 cis-trans isomerizing activity. PIN1 inhibitor API-1 up-regulates miRNA biogenesis by retaining active XPO5 conformation and suppresses HCC development.
D4017 Pinatuzumab vedotin Pinatuzumab Vedotin (RG-7593, DCDT2980S, DCDT-2989S), is an antibody-drug conjugate (ADC) composed of CD22 (Sialic acid binding Ig-like lectin 2, SIGLEC2, SIGLEC-2, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14) antibody and cytotoxic agent monomethyl auristatin E (MMAE) conjugated through maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker.
S6473 Pinaverium bromide Pinaverium bromide (Icosapentaenoic acid) acts as a calcium channel blocker and is useful for functional gastrointestinal disorders.
E0848 Pinealon Pinealon is a tripeptide exhibiting neuroprotective effects. This peptide inhibits reactive oxygen species (ROS) buildup and blocks ERK 1/2 activation. It enhances functional activity of key brain tissue cellular components while decreasing spontaneous cell death rates. Studies demonstrate Pinealon's protective effects against prenatal hyperhomocysteinemia in rat offspring.
F0490 PINK1 Antibody [B2H2]
F3247 PINK1 Antibody [M4A21]
S3941 Pinocembrin Pinocembrin (Dihydrochrysin, Galangin flavanone, 5,7-Dihydroxyflavanone) is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry. Its vast range of pharmacological activities has been well researched including antimicrobial, anti-inflammatory, antioxidant, and anticancer activities.
S7062 Pinometostat (EPZ5676) Pinometostat (EPZ5676) is an S-adenosyl methionine (SAM) competitive inhibitor of protein methyltransferase DOT1L with Ki of 80 pM in a cell-free assay, demonstrating >37,000-fold selectivity against all other PMTs tested, inhibits H3K79 methylation in tumor. Phase 1.
S9436 Pinoresinol dimethyl ether Pinoresinol dimethyl ether, which could be isolated from the wood of the basal tree Humbertieae, show a variety of activities as the inhibitor of cyclic AMP phosphodiesterase.
S2590 Pioglitazone (U-72107) Pioglitazone is a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, used to treat diabetes; A weak activator for full-length hPPARα, but not full-length hPPARδ.
S2046 Pioglitazone HCl Pioglitazone HCl (AD-4833, U-72107E) is an inhibitor of cytochrome P450 (CYP)2C8 and CYP3A4 enzymes. Pioglitazone HCl inhibits CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively. Pioglitazone HCl is also a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist with EC50 of 0.93 μM and 0.99 μM for human PPARγ and mouse PPARγ, respectively. Pioglitazone HCl inhibits mitochondrial iron uptake, lipid peroxidation, and subsequent ferroptosis.
F1237 PIP4K2A Antibody [L5H16]
S6322 Pipecolic acid Pipecolic acid (piperidine-2-carboxylic acid), a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF, is an important regulator of immunity in plants and humans alike.
S5051 Pipemidic acid Pipemidic acid (Acido pipemidico) is a pyridopyrimidine antibiotic derivative of piromidic acid with activity against gram-negative bacteria including Pseudomonas aeruginosa and some gram-positive bacteria. Pipemidic acid is an inhibitor of DNA gyrase that is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA. It can be used for the research of intestinal, urinary, and biliary tract infections.
E8115 Piperacetazine Piperacetazine (Quide, Psymod) is a potent inhibitor of PAX3::FOXO1 and a prodrug of a phenothiazine antipsychotic drug with a mechanism of action similar to chlorpromazine. Piperacetazine has antitumor activity.
E4810 Piperacillin Piperacillin is a broad-spectrum β-lactam antibiotic with potent bactericidal activity against Gram-negative bacteria and selects Gram-positive strains via penicillin-binding proteins.
S4222 Piperacillin Sodium Piperacillin (CL227193,Pipracil) is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.
S5355 Piperaquine phosphate Piperaquine phosphate is an orally active bisquinolone antimalarial drug.
E4809 Piperaquine tetraphosphate tetrahydrate Piperaquine tetraphosphate tetrahydrate is an inhibitor of autophagy . It is a bisquinoline antimalarial agent effective against Plasmodium falciparum. Piperaquine tetraphosphate tetrahydrate is useful in antimalarial research.
S4443 Piperazine adipate Piperazine adipate is a broad spectrum anthelmintic agent that inhibits malate oxidation in Ascaridia galli and Heterakis gallinae.
E1063 Piperazine Erastin Piperazine Erastin is an analog of Erastin, which can induces ferroptosis in cancer cells, an iron-dependent form of nonapoptotic cell death.
S2344 Piperine Piperine (1-Piperoylpiperidine) is the alkaloid responsible for the pungency of black pepper and long pepper, which has also been used in some forms of traditional medicine and as an insecticide.
S7551 Piperlongumine Piperlongumine (PPLGM, Piplartine), a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1; also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells.
S6139 Piperonyl acetone Piperonyl acetone is a food additive used in food flavouring.
S4831 Piperonyl butoxide Piperonyl butoxide (PBO, Butacide, Ethanol butoxide, Pyrenone 606,ENT-14250) is a man-made pesticide synergist, working with insect killers to increase their effectiveness.Piperonyl butoxide is an inhibitor of cytochrome P450 monooxygenases(P450s).
S0116 Piperoxan hydrochloride Piperoxan hydrochloride (Benodaine, Fourneau 933, F933, DL-Piperoxan) is an antagonist of α2 (alpha 2) adrenoceptor.
E2941 PIPES PIPES (1,4-Piperazinediethanesulfonic acid) is an important component of PIPES buffer agent used in biochemistry. PIPES buffer in combination with glutaraldehyde and formaldehyde helps in optimal fixation of fungal zoospores for fluorescence microscopy and electron microscopy.
S4447 Pipobroman Pipobroman (PB, Vercyte), a neutral amide of piperazine, acts as an alkylating agent with antiproliferative activity.
S3070 Piracetam Piracetam (UCB 6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.
S1393 Pirarubicin Pirarubicin is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into DNA and interacts with topoisomerase II, used as an antineoplastic agent.
S0779 Pirenperone Pirenperone (R-47456, R-50656), a quinazoline derivative, is a selective antagonist of SR-2A (5-HT2 serotonin receptor) when employed in low doses. Pirenperone behaves like a typical neuroleptic when used in higher doses (greater than 0.1 mg/kg).
S3662 Pirenzepine dihydrochloride Pirenzepine is an antimuscarinic agent which inhibits gastric acid secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular and urinary functions.
S2907 Pirfenidone Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Pirfenidone attenuates chemokine (CC motif) ligand-2 (CCL2) and CCL12 production with anti-fibrotic activity. Phase 3.
S3656 Piribedil Piribedil (Trivastal, Trivastan) is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties.
S1713 Piroxicam Piroxicam (CP 16171) is a non-selective COX inhibitor, used in the treatment of rheumatoid and osteoarthritis.
S0159 Pirozadil Pirozadil is a hypolipidemic agent.
S9825 Pirtobrutinib (LOXO-305)

Pirtobrutinib (LOXO-305, LY 3527727, RXC-005) is a highly selective, non-covalent, next generation BTK inhibitor with an IC50 of 5.69 nM in WT BTK HEK cells. Pirtobrutinib shows more than 300-fold selective for BTK over 98% of 370 other kinases.

E6038 Pitavastatin Pitavastatin (NK-104) is a highly potent inhibitor of HMG-CoA reductase with an IC50 of 6.8 nmol/L, which significantly enhances LDL receptor activity and lowers LDL cholesterol (LDL-C) levels. It also inhibits cholesterol synthesis in vitro and has the potential to manage hypercholesterolemia and reducing cardiovascular risk. 
S1759 Pitavastatin (NK-104) Calcium Pitavastatin calcium, a novel member of the medication class of statins, is a calcium salt formulation of pitavastatin which is a highly effective HMG-CoA reductase inhibitor. Pitavastatin Calcium attenuates AGEs-induced mitophagy via inhibition of ROS generation. Pitavastatin Calcium induces autophagy and apoptosis.
E4955 Pitolisant Pitolisant(BF2.649, Tiprolisant) is a potent, selective antagonist of the non-imidazole histamine H3 receptor, with a Ki value of 0.16 nM and an EC50 of 1.5 nM as an inverse agonist. It enhances the activity of histaminergic neurons, promoting vigilance and cognitive function. It is useful in research on wakefulness, memory deficits, and cognitive disorders.
S5926 Pitolisant hydrochloride Pitolisant (Tiprolisant, BF-2649) acts as a high-affinity competitive antagonist (Ki=0.16 nM) and as an inverse agonist (EC50=1.5 nM) at the human histamine H3 receptor subtype.
F2651 PITSLRE/CDK11 Antibody [K17G19]
S9670 Pitstop 2 Pitstop 2 is an inhibitor of the interaction of amphiphysin with the amino terminal domain of clathrin that inhibits both clathrin-dependent endocytosis (CDE) and clathrin independent endocytosis (CIE).
S5473 Pivmecillinam hydrochloride Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections.
S5059 Pixantrone Maleate Pixantrone (BBR-2778) is a novel aza-anthracenedione compound with antitumor activity. It is a weak topoisomerase II inhibitor and forms stable DNA adducts through alkylation with specificity for DNA hypermethylated sites.
S5770 Pizotifen Pizotifen (Pizotyline, BC-105) is a potent antagonist of 5-Hydroxytryptamine (5-HT, Serotonin) 5-HT2 receptor with a high affinity for 5-HT1C binding site.
S1394 Pizotifen Malate Pizotifen Malate (Sandomigran, pizotyline,BC-105) is a benzocycloheptane based agent used for recurrent migraine headaches.
E4637 PK 11195 PK 11195 (RP 52028) is a translocator protein (TSPO) ligand, a potent and selective antagonist of peripheral benzodiazepine receptorwith high affinity Ki of 3.1 nM in cerebellum and 4.1 nM in spinal cord. It is also an antagonist of human constitutive androstane receptor (hCAR), and human pregnane X receptor (PXR). It displaces [3H] RO5-4864 from its binding sites across organs and also targets Leishmania in chemotherapy.
S8728 PK11000 PK11000 stabilizes the DBD of both WT and mutant p53 proteins by covalent cysteine modification without compromising DNA binding and effective in inducing cell death.
E1735 PK11007 PK11007 is a thiol-reactive anticancer agent that stabilizes p53 via selective alkylation of two surface cysteines without compromising its DNA binding. It induces mutant p53 cancer cell death by increasing reactive oxygen species (ROS) levels.
S0534 PK150 PK150 is an analogue of Sorafenib, which shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 µM, respectively.
E2367 PK68 PK68 is a potent orally active and specific inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM.
F0588 PKA C-α Antibody [P7L4] cAMP Protein Kinase Catalytic subunit,PKA C-α
F3842 PKA R2/PKR2 Antibody [D10M9]
F1294 PKA RI-α Antibody [J14D6]
F2343 PKC ζ Antibody [C22E16] PKC zeta,PKC ζ,PKCζ
F0745 PKC ζ Antibody [J7H1] PKC zeta,PKC ζ,PKCζ
S6577 PKC-theta inhibitor PKC-theta inhibitor (compound 20) inhibits PKC-θ with an IC50 of 18 nM.
F6058 PKCα Antibody [B21A18]
F1008 PKCα Antibody [H18C22] PKC,PKC alpha,PKC α,PKCα,Protein Kinase Calpha
F3769 PKCδ Antibody [G9A5] PKC delta,PKC δ,PKCδ
F0744 PKCδ Antibody [N6G7] PKC delta,PKC δ,PKCδ
F0644 PKCε Antibody [N2L13] PKC epsilon,PKC ε,PKCε
F0898 PKCθ Antibody [C21J10] PKC theta/PRKCQ,PKC θ,PKCθ
F0899 PKCι/λ Antibody [M11C7]
F3042 PKD/PKCμ Antibody [D22N3] PKC mu/PKD,PKD/PKCμ,PRKD1
F1238 PKD2 Antibody [F19K7]
F0792 PKD3/PKCν Antibody [N18G12]
S0152 PKG drug G1 PKG drug G1 is an activater of Protein Kinase G Iα (PKG Iα) targeting C42, resulting vasodilation and blood pressure lowering.
P1153 PKG inhibitor peptide PKG inhibitor peptide is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG), with a Ki of 86 μM.
F0589 PKG-1 Antibody [B18P19]
P1154 PKI 14-22 amide,myristoylated PKI 14-22 amide, myristoylated is a potent cAMP-dependent PKA inhibitor, which can reduce the IgG-mediated phagocytic response and also inhibits neutrophil adhesion.
E7109 PKI(5-24) PKI(5-24) is a potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase), with a Ki of 2.3 nM. It can be used for research to study hormonal regulation of the CAMP-dependent protein kinase.
S2739 PKI-402 PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3Kα/β/γ/δ and mTOR with IC50 of 2 nM/7 nM/16 nM/14 nM and 3 nM, respectively; also potent to PI3Kα mutants E545K and H1047R.
F4052 PKM Antibody [F7K24]
F0491 PKM1 Antibody [H3D14]
F0793 PKM1/2 Antibody [E6H20] PKM,PKM1/2
F0295 PKM2 Antibody [F23E18]
F2704 PKM2 Antibody [L22N15]
S8616 PKM2-IN-1 (Compound 3k) PKM2 inhibitor(Compound 3K, PKM2-IN-1) displays PKM2 inhibitory activity with the IC50 value of 2.95 μM. The IC50 value for PKM1 is 4-5-fold higher than that for PKM2.
E6517 PKN1 PKN1/2-IN-1 is a cell-permeable compound that inhibits PKN1 and PKN2, with IC50 values of 16 nM and 210 nM, and Ki values of 8 nM and 108 nM, respectively. In NanoBRET assays, it shows intracellular PKN2 binding with an IC50 of 2.1 μM. This compound is applicable for investigating tumor cell migration and related physiological processes.
F4608 PKR Antibody [F1M21]
F1207 PKR Antibody [K23G2]
E2388 PKR-IN-2 PKR-IN-2 is a pyruvate kinase isoform PKR activator extracted from patent WO2014139144A1, compound 160, which can be used for the research of PKR function related diseases, including cancer, diabetes, obesity, autoimmune disorders, and benign prostatic hyperplasia.
S9668 PKR-IN-C16 PKR-IN-C16 (imoxin, C16, Imidazolo-oxindole PKR inhibitor C16) is a specific inhibitor of RNA-dependent protein kinase (PKR, Protein Kinase R, EIF2AK2). PKR-IN-C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component.
E4677 PKUMDL-LC-101-D04 PKUMDL-LC-101-D04(GPX4-Activator-1d4) is a potent allosteric activator of Glutathione peroxidase 4 (GPX4) effectively suppressing ferroptosis and inflammation. It enhances GPX4 activity by 150% at 20 µM in a cell-free assay and 61 µM in cell extracts, also providing protection against cholesterol hydroperoxide (ChOOH)-induced damage.
F1350 Plac8 Antibody [P15H12]
S3254 Plantagoside Plantagoside, a flavanone glucoside isolated from the seeds of Plantago asiatica, is a specific and non-competitive alpha-mannosidase inhibitor with IC50 of 5 μM.
S9077 Plantamajoside Plantamajoside (Y0160, C10485), a hydroxycinnamic acid, is used as a biomarker in chemotaxonomical studies, and is a compound with numerous biological applications and considerable pharmacological potential.
F0492 PLC1 Antibody [H3H20] Phospholipase C gamma 1/PLC-gamma-1,PLC γ1,PLCgamma-1,PLCγ1
F4457 PLCβ1 Antibody [N12B19]
F7497 PLCβ3 Antibody [E24D14]
F3015 PLCγ2 Antibody [P20P21] PLC γ2,PLCγ2
F1493 PLD2 Antibody [B7K12]
P1121 Plecanatide

Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis.

S0436 Pleconaril Pleconaril (APO-P001, Picovir, VP 63843, WIN 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication with IC50 of < 0.050 μM.
F2118 Plectin Antibody [G16H14] Plectin,Plectin-1
S3013 Plerixafor (AMD3100) 8HCl Plerixafor (AMD3100, JM 3100,Plerixafor Octahydrochloride,AMD3100 octahydrochloride,SID791 octahydrochloride) 8HCl is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor can be used as an anti-HIV agent.
S4436 Pleuromutilin Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
F1351 Plexin A4 Antibody [G22C13]
S8145 Plicamycin Plicamycin (Mithramycin A) a selective inhibitor of Sp1, is a natural polycyclic aromatic polyketide isolated from Streptomyces strains. It binds to GC-rich DNA sequences, displacing Sp1 transcription factor from oncogene promoters, inhibiting their expression, with anti-tumor and neuroprotective effects.
S1176 Plinabulin Plinabulin is a vascular disrupting agent (VDA) against tubulin-depolymerizing with IC50 of 9.8~18 nM in tumor cells. Phase 1/2.
F3264 PLK1 Antibody [F22N13] Plk,PLK1
F0393 PLK1 Antibody [P4E9] Plk,PLK1
F1257 PLK3 Antibody [M9B6]
A2569 Plozalizumab (Anti-CCR2 / CD192) Plozalizumab (Anti-CCR2 / CD192) is a specific humanized monoclonal antibody targeting CCR2. Plozalizumab can be used for malignant melanoma research. MW:145.5 KD.
S0515 PLpro inhibitor  PLpro inhibitor (compound 6) is a potent papain-like protease (PLpro)/deubiquitinase (DUBs) inhibitor with IC50 of 2.6 μM and EC50 of 13.1 μM that blocks SARS virus replication.
S4777 Plumbagin Plumbagin (Plumbagine, Plumbaein, Plumbagone), a quinoid constituent isolated from the root of the medicinal plant Plumbago zeylanica L, exerts anticancer and antiproliferative activities in animal models and in cell culture.
S7752 Pluripotin (SC1) Pluripotin (SC1) is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Maintains embryonic stem cell (ESC) self-renewal. Pluripotin also inhibits RSK1, RSK2, RSK3 and RSK4 with IC50 of 0.5 µM, 2.5 µM, 3.3 µM and 10.0 µM, respectively.
S8076 PluriSIn #1 (NSC 14613) PluriSIn #1 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs.
S6936 Pluronic F-68 Pluronic F-68 (Poloxamer 188, P188, MST-188) is a triblock copolymer of the form polyethylene oxide-polypropylene oxide-polyethylene oxide (PEO-PPO-PEO) with surface-active properties. Pluronic F-68 is used in the pharmaceutical industry as an excipient in various formulations and drug delivery systems. Pluronic F-68 is effective in the repair/recovery of damaged cell membranes.
F2799 PLVAP/PV-1 Antibody [E23J22] Panendothelial Cell Antigen,PLVAP,PLVAP/PV-1
S1152 PLX-4720 PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.
S1267 PLX4032 (Vemurafenib) Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.
S8739 PLX51107 PLX51107 is as a novel BET inhibitor with modest preference for bromodomain-1 (BD1) versus bromodomain-2 (BD2) within each BET protein (Kd = 1.6, 2.1, 1.7, and 5 nM for BD1 and 5.9, 6.2, 6.1 and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively. Among non-BET proteins, PLX51107 shows significant interactions only with the bromodomains of CBP and EP300 (p300) (Kd in the 100 nM range).
S8874 PLX5622 PLX5622 is a highly selective CSF-1R inhibitor (IC50 < 10 nmol/L), showing > 20-fold selectivity over KIT and FLT3.
S7965 PLX8394 (Plixorafenib, FORE8394) Plixorafenib (PLX8394) is a next-generation, orally available, small-molecule BRAF inhibitor with IC50 values of 3.8 nM, 14 nM and 23 nM for BRAF(V600E), WT BRAF and CRAF respectively. It has potential antineoplastic activity.
E8284 PM534 PM534 is a potent microtubule-targeting agent (MTA) that binds the colchicine-binding domain (CBD) and inhibits tubulin assembly with IC50 values ranging from 0.8 to 3.2 nM. It also significantly inhibits tumor growth in mouse xenograft models of human non-small cell lung cancer.
S7791 PMA chemical (Phorbol 12-myristate 13-acetate) PMA (Phorbol 12-myristate 13-acetate), a potent activator of PKC, is active at nanomolar concentrations. Phorbol 12-myristate 13-acetate (PMA) induces sphingosine-1-phosphate (S1P).PMA has strong excitability on the skin and mucous membrane. Special protection is required when using PMA. Wear gloves and mask to avoid direct contact in any way.
F2711 PMCA ATPase Antibody [C12G10]
F2539 PML Antibody [F17K6] PML,PML Protein
S0189 PMPA tetrasodium salt PMPA tetrasodium salt (PMPA sodium) is a potent and selective inhibitor of glutamate carboxypeptidase 2 (GCP II/NAALADase).
F2023 PMS2 Antibody [N24N11]
S3025 PMSF PMSF (Phenylmethylsulfonyl Fluoride, Benzylsulfonyl fluoride) is an irreversible serine/cysteine protease inhibitor.
P1208 PMX 205 acetate

PMX 205 acetate is a cyclic hexapeptide that acts as a potent C5a receptor (C5aR, CD88) antagonist with an IC50 of 31 nM.

S6239 PMX-53 PMX-53 is a potent CD88 (C5aR) antagonist and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2).
S9200 Pneumocandin B0 Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S4614 PNPP PNPP (p-nitrophenyl phosphonate) is a substrate for alkaline and acid phosphatases used in enzyme-linked immunoassay (ELISA) and conventional spectrophotometric assays.
S5930 PNU 282987 HCl PNU 282987 is a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors with Ki value of 26 nM for the rat receptor.
S2629 PNU-120596 PNU-120596 (Nsc 216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.
S0720 PNU-282987 PNU-282987 is a novel selective agonist of the alpha7 nAChR with Ki of 26 nM for rat alpha7 nAChR. PNU-282987 shows no activity at all tested monoamine, muscarine, glutamate, and GABA receptors, except 5-HT3 receptors with Ki of 930 nM.
S0521 PNU-282987 S enantiomer free base PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base, which is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist.
S8429 PNU-74654 PNU-74654 disrupts the Wnt signaling pathway via inhibition of the interaction (KD50=450 nM) between β-catenin and Tcf4.
S2345 Podophyllotoxin (Podofilox) Podophyllotoxin (Condylox,Podofilox) is a lignan (lignans) found in podophyllin resin from the roots of podophyllum plants.
F0746 PODXL Antibody [F8E16] PODXL,TRA-1-60,TRA-1-60 (Podocalyxin),TRA-1-60 (R),TRA-1-60(S) (TRA-1-60(S))
S9094 Pogostone Pogostone is one of the secondary metabolites from Pogostemon cablin (Blanco) Benth. (Lamiaceae), serving as the effective component of the antimicrobial activity.
D4012 Polatuzumab vedotin-piiq Polatuzumab vedotin-piiq (polatuzumab vedotin, DCDS4501A, RG7596) is an antibody-drug conjugate (ADC) composed of a monoclonal antibody against CD79b (a B cell receptor component) and the anti-mitotic cytotoxic agent monomethyl auristatin (MMAE). It is used for the treatment of relapsed/refractory diffuse large B-cell lymphoma (DLBCL).
F2835 POLD1 Antibody [A14M15]
F3623 POLD3 Antibody [E13B7]
F3409 POLDIP2 Antibody [N1K14]
F2171 POLG Antibody [M21J18] DNA Polymerase γ,POLG
S3505 Polidocanol Polidocanol (Polyoxyethylene lauryl ether, Polyoxyethyleneglycol Dodecyl Ether, Brij30, Laureth-23, Varithena) is a sclerosant used for treating uncomplicated spider veins and reticular veins in the lower extremities.
S1074 Poliumoside Poliumoside exhibits significant inhibition of advanced glycation end product formation with IC50 values of 19.69 µM. In the rat lens aldose reductase assay.Poliumoside exhibits greater inhibitory effects on rat lens aldose reductase(RLAR) with IC50 values of 8.47 µM.
S5893 Poloxin Poloxin is a non-ATP competitive Polo-like Kinase 1 polo-box domain (Plk1 PBD) inhibitor with an apparent IC50 of 4.8 μM. Poloxin's IC50 values against the PBDs of Plk2 and Plk3 as Plk1 are approximately 4-fold and 11-fold higher, respectively in fluorescence polarization assays.
E6541 PolQi2 PolQi2 is a PolΘ inhibitor that specifically targets the N-terminal helicase domain of PolΘ, thereby suppressing alt-EJ (alternative end-joining) repair. This compound improves the accuracy and integration efficiency of gene editing across multiple loci and diverse cell lines. Additionally, PolQi2 demonstrates synergistic effects with DNA-PK inhibitors in reducing Cas9-mediated off-target activity. Its application is suitable for gene editing studies.
F5025 POLR1A Antibody [E1L22]
F1239 POLR3A Antibody [E12G4]
E4026 Poly(2-hydroxyethyl methacrylate) Poly(2-hydroxyethyl methacrylate) is one of the most important hydrogels in the world of biomaterials. It is the basic component of contact lenses and is also used in the implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agents, etc.
E0518 Poly(I:C) (Polyinosinic-Polycytidylic Acid) Polyinosinic acid-polycytidylic acid (Polyinosinic-polycytidylic acid; Poly(I:C)), a double-stranded RNA that induces innate immunity in mammals, is a candidate immunopotentiator for pharmaceuticals. Polyinosinic acid-polycytidylic acid is dsRNA formed by the long chain decomposition of muscle poly (I) homopolymer into poly (C) homopolymer.
E2904 Poly(vinyl alcohol) Poly(vinyl alcohol) is an artificial polymer that is used in many industries, such as textile, paper industry, and food packaging industry due to its high chemical and thermal stability. Poly(vinyl alcohol) is also an excellent source for fiber, polymer, textile, surface, organic.
E4024 Poly-D-lysine hydrobromide Poly-D-lysine hydrobromide is a synthetic polymeric substrate most widely used in neural cell culture. It removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells without affecting PrPC.
F0957 Poly/Mono-ADP Ribose Antibody [A22J18] Poly (ADP-Ribose) Polymer,Poly/Mono-ADP Ribose
E1299 Polybrene (Hexadimethrine Bromide) Polybrene (Hexadimethrine bromide) is a cationic polymer which is widely used as supplement for retroviral and lentiviral transduction.
E7055 Polydatin Polydatin is a natural potent stilbenoid polyphenol and a resveratrol derivative with improved bioavailability. Polydatin exhibits diverse biological effects primarily by influencing key signaling pathways linked to inflammation, oxidative stress, and programmed cell death. By regulating multiple inflammatory mediators, polydatin demonstrates strong anti-inflammatory potential, while simultaneously activating antioxidant defenses and inhibiting oxidative mechanisms across a range of pathological conditions.
E4019 Polyethylenimine Polyethylenimine (PEI) is a hydrophilic cationic polymer that acts as a low toxicity and efficient gene vector.
S9386 Polygalacic acid Polygalacic acid is the triterpenoid tetrahydroxyacid isolated from Polygala paenea L.. Polygalacic acid (0-100 μM; 24 hours) significantly decreases the mRNAexpressions of MMP-3, MMP-9, MMP-13 and COX-2, which are significantly increased by IL-1β, in a dose-dependent manner.
S9241 Polygalaxanthone III Polygalaxanthone III is a natural product with the efficacy of tranquilization, glaangal, eliminating sputum and detumescence. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM.
S9238 Polygalic acid Polygalic acid (Senegenic acid), a triterpenoid saponin, shows expectorant, emetic and stimulant effects.
E4998 Polyinosinic-polycytidylic acid sodium Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic double-stranded RNA (dsRNA) analogue that activates the MDA-5 receptor in the cytoplasm and TLR3 in endosomal compartments. This activation promotes the production of type I interferons and induces apoptosis in cancer cells, particularly those that lack protective anti-apoptotic mechanisms like Bcl-xL.
S1395 Polymyxin B sulphate Polymyxin B (Aerosporin, PMB, Poly-RX) is an antibiotic primarily used for resistant gram-negative infections.
S3279 Polyphyllin B (Formosanin C) Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis.
S9114 Polyphyllin I Polyphyllin I, a small molecular monomer extracted from Rhizoma of Paris polyphyllin, is used in the treatment of infectious disease and cancer. Polyphyllin I inhibits proliferation and induces apoptotic cell death in U251 cells. Polyphyllin I is an activator of the JNK signaling pathway with a potential anti-glioma effect.
S9302 Polyphyllin VI Polyphyllin VI derived from Paris polyphylla possess anti-cancer activities.
S9515 Polyphyllin VII Polyphyllin VII (Y-0166), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, cervical cancer, hepatocellular carcinoma and osteosarcoma.
E0185 Polytetrafluoroethylene

Polytetrafluoroethylene (PTFE) is a biomedical material and has excellent non-stick properties with an exceptionally low coefficient of friction.

S6001 pomaglumetad (LY404039) LY404039 is a potent agonist of recombinant human mGlu2/mGlu3 receptors with Ki of 149 nM/92 nM, shows >100-fold selectivity over ionotropic glutamate receptors, glutamate transporters, and other receptors. Phase 3.
S1567 Pomalidomide (CC-4047) Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN). Pomalidomide promotes apoptosis and cell cycle arrest.
F3420 POMC Antibody [B13A5] ACTH,POMC
E1028 POMHEX POMHEX, is a potent ENO2 -specific inhibitor of enolase and a racemic mixture, a cell-permeable pivaloyloxymethyl (POM) prodrug of HEX. It is also glycolysis inhibitor and can be used for the research of cancer.
S9562 Pomolic acid Pomolic acid is a pentacyclic triterpene isolated from Euscaphis japonica, and is highly effective in inhibiting cell growth and induces apoptosis.
F2376 PON1 Antibody [G1G1]
F3855 PON2 Antibody [K8P11]
S1490 Ponatinib (AP24534) Ponatinib is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively. Ponatinib (AP24534) inhibits autophagy.
E7000 Ponatinib hydrochloride Ponatinib hydrochloride is a potent, orally available multi-targeted inhibitor of Pan BCR-ABL kinase. It potently inhibits ABL with an IC50 of 0.37 nM, also inhibits SRC , VEGFR2, FGFR1, PDGFRα, LYN with an IC50s of 5.4 nM, 1.5 nM, 2.2 nM, 1.1 nM, 0.24 nM respectively and exhibits significant potential in cancer reserach.
S4497 Ponceau S Ponceau S (Acid Red 112) is the most commonly used stain for immunoblotting protocols. Ponceau S dye is applied as an acidic aqueous solution, and the proteins on the membrane are stained with red color.
S9165 Poncirin Poncirin (Isosakuranetin-7-neohesperidoside), extracted from trifoliate orange, has anti-bacterial and anti-inflammatory activities.
S8241 Ponesimod (ACT-128800) Ponesimod (ACT-128800) is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM.
E0204 Poricoic acid A Poricoic acid A is isolated from the surface layer of Poria cocos. Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis. Poricoic acid A also is a modulator of tryptophan hydroxylase-1 (TPH-1).
S1257 Posaconazole Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.
E2843 Poseltinib Poseltinib (HM71224, LY3337641) shows a highly selective inhibition for Bruton’s tyrosine kinase (BTK) with IC50 of 1.95 nM, in which the selectivity toward other BMX, TEC and TXK are 0.3, 2.3 and 2.4 fold, respectively. 
S4806 Potassium 1-Naphthaleneacetate Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.
S4843 Potassium acetate Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
E4470 Potassium Chloride Potassium chloride is an inorganic salt commonly used in fertilizer industry. It is also extensively used as a potassium supplement.
E4002 Potassium D-gluconate Potassium D-gluconate(Potassium Gluconate) is an orally active carboxylic acid by the oxidation with antiseptic and chelating properties.
S5799 Potassium guaiacolsulfonate hemihydrate Potassium guaiacolsulfonate hemihydrate (Potassium Hydroxymethoxybenzenesulfonate, Sulfogaiacol) is used as an expectorant for relieving symptoms of cough and mucus in the chest due to respiratory infections, asthma, colds, or hay fever.
S1897 Potassium Iodide Potassium Iodide is used to treat overactive thyroid and to protect the thyroid gland from the effects of radiation from inhaled or swallowed radioactive iodine.
E0353 Potassium Oxonate (Oteracil Potassium)

Potassium oxonate (Oxonic Acid Potassium Salt) is a selectively competitive uricase inhibitor, produced hyperuricemia (HUA) in rodents.

E0195 Potassium phosphate dibasic Potassium phosphate dibasic (Dipotassium phosphate, K2HPO4) is often used as a fertilizer, food additive, and buffering agent.
E0166 Potassium phosphate monobasic Potassium phosphate monobasic (Monopotassium phosphate) is a commonly used in biological assay buffers. Potassium phosphate monobasic is moderate to highly concentrated aqueous solutions of potassium phosphate monobasic for the production of phosphate buffers and other laboratory applications. Potassium phosphate monobasic (KH2PO4) also used as a fertilizer, food additive, and buffering agent.
S3142 Potassium sorbate

Potassium sorbate (Sorbic acid potassium) is a nonpoisonous food preservative isolated from Sorbus aucuparia. Potassium sorbate is an effective inhibitor of most molds and yeasts and some bacteria.

S6020 Potassium thioacetate Potassium thioacetate is widely used as a sulfur source in the synthesis of sulfur-containing organic compounds. It has been employed for the synthesis of heterocycles, polymers, transition-metal ligands, nanoparticles, bioactive compounds and macromolecular inclusion complexes.
E4737 Potrasertib Potrasertib (IMP7068, WEE1-IN-10) is a potent and selective inhibitor of WEE1 Kinase. It displays antitumor activity and is well-tolerated in patients with advanced solid tumors.
S4678 Povidone iodine Povidone iodine (Betadine, PVP iodine, PVP-I, Isodine) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. Povidone iodine displays excellent antibacterial activity against MRSA and MSSA strains with MICs of 31.25 mg/L and 7.82 mg/L, respectively. Povidone iodine is used as a topical antiseptic in surgery and for skin and mucous membrane infections, as well as as an aerosol.
S7358 Poziotinib (NOV120101, HM781-36B) Poziotinib is an irreversible pan-HER inhibitor with IC50 of 3.2 nM, 5.3 nM and 23.5 nM for HER1, HER2, and HER4, respectively. Poziotinib also induces apoptosis and G1 cell cycle arrest. Phase 2.
S7060 PP1 PP1 (AGL 1872, EI 275) is a potent and selective Src inhibitor for Lck/Fyn with IC50 of 5 nM/ 6 nM.
S7008 PP2 (AGL 1879) PP2 (AG 1879, AGL 1879), a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM in cell-free assays, ~100-fold less potent to EGFR, inactive for ZAP-70, JAK2 and PKA.
F0645 PP2A A Subunit Antibody [P15H17]
F0794 PP2A B Subunit Antibody [F20H10] PP2A B Subunit,PP2A-B55-α,PPP2R2A
F3812 PP2A C subunit Antibody [C1E4]
F0441 PP2A C Subunit Antibody [P20A19] PP2A alpha + beta,PP2A C Subunit,PP2A-Cα/β
F1240 PP2C-α Antibody [L3F21] PP2C-α,PPM1A
F4266 PPARα Antibody [P17E1]
F3621 PPP1CA + PPP1CB Antibody [D19B4]
F2108 PPP1CB Antibody [P21B20]
F3715 PPP2R5D Antibody [H6G7]
S0198 PPQ-102 PPQ-102 (CFTR Inhibitor IV) is a potent inhibitor of CFTR. PPQ-102 can completely inhibit CFTR chloride current with IC50 of ~90 nM.
S8003 PQ 401 PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.
S8784 PQR620 PQR620 is a novel, selective, orally bioavailable and brain penetrant dual TORC1/2 inhibitor. PQR620 has anti-tumor activity across 56 lymphoma models with a median IC50 of 250 nM after 72 h of exposure.
S2853 PR-171 (Carfilzomib) Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM in ANBL-6 cells, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities. Carfilzomib activates prosurvival autophagy and induces cell apoptosis.
S7130 PR-619 PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM in a cell-free assay. PR-619 activates autophagy.
S1515 Pracinostat (SB939) Pracinostat (SB939) is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with exception for HDAC6. It has no activity against the class III isoenzyme SIRT I. Pracinostat (SB939) induces apoptosis in tumor cells. Phase 2.
E7561 Pradigastat Pradigastat (LCQ-908) is a potent and selective inhibitor of DGAT1 with an IC50 of 57 nM in hDGAT1. It also inhibits OATP1B1, OATP1B3 , and OAT3 activity in a concentration-dependent manner, with an IC50 of 1.66 μM, 3.34 μM, and 0.973 μM, respectively.
S9315 Praeruptorin A Praeruptorin A, a naturally existing pyranocumarin, is isolated from the dried root of Peucedanum praeruptorum Dunn. Praeruptorin A inhibits p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca2+ oscillation. Praeruptorin A can significantly upregulates multidrug resistance-associated protein 2 expression via the constitutive androstane receptor-mediated pathway in vitro, and this should be taken as an herb-drug interaction.
S9392 Praeruptorin B Praeruptorin B is an important compound isolated from Bai-hua Qian-hu and has been reported to exert multiple biochemical and pharmacological activities.praeruptorin B exerts lipid-lowering effects through inhibits SREBPs and could serve as a possible therapeutic option to improve hyperlipidemia and hyperlipidemia-induced comorbidities.
S9151 Praeruptorin E Praeruptorin E, isolated from Peucedanum praeruptorum Dunn., is a cardiotonic agent with selective cardiac calcium channel agonistic effect.
S1497 Pralatrexate Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines. Pralatrexate induces tumor cell apoptosis.
S4575 Pralidoxime chloride Pralidoxime chloride (2-PAM) is an antidote to organophosphate pesticides and chemicals; An acetylcholinesterase (AChE) reactivator.
S5100 Pralidoxime Iodide Pralidoxime Iodide (2-PAM) is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning.
D4039 Praluzatamab ravtansine Praluzatamab ravtansine (CX-2009) is a conditionally activated Probody drug conjugate (PDC) comprising an anti-CD166 mAb conjugated to DM4, with a protease-cleavable linker and a peptide mask that limits target engagement in normal tissue and circulation.
S2460 Pramipexole Pramipexole (SND 919,Mirapexin,Sifrol,Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.
S2011 Pramipexole 2HCl Monohydrate Pramipexole 2HCl Monohydrate is a novel non-ergoline dopamine (DA) agonist, used to treat Parkinson's disease.
S5066 Pramipexole dihydrochloride Pramipexole dihydrochloride (SND919) is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS) with Ki values of 3.9 nM, 2.2 nM, 0.5 nM and 5.1 nM for D2S receptor, D2L receptor, D3 receptor and D4 receptor.
S2594 Pramiracetam Pramiracetam (CI-879,Pramistar) is a more potent nootropic drug derived from piracetam.
P1063 Pramlintide Acetate Pramlintide Acetate is a prescription drug that can lower blood sugar in people with diabetes.
S4092 Pramoxine HCl Pramoxine(Pramocaine hydrochloride) is a topical local anesthetic that has been shown to have antipruritic properties.
S2436 Pranidipine Pranidipine (Acalas, OPC 13340) is a new 1,4-dihydropyridine calcium channel blocker. Pranidipine can enhance cyclic GMP-independent nitric oxide-induced relaxation of the rat aorta.
S1829 Pranlukast Pranlukast (ONO-1078,ono-rs-411) is an orally administered, and selective antagonist of the cysteinyl leukotrienes (LT) C(4), LTD(4) and LTE(4), used in the prophylactic treatment of chronic bronchial asthma.
E6047 Pranlukast hemihydrate Pranlukast hemihydrate (ONO-1078 hemihydrate) is an antagonist of cysteinyl leukotriene receptor-1 (CysLT1) that blocks leukotrienes such as LTC4, LTD4, and LTE4, reducing bronchoconstriction and airway inflammation. It also inhibits NF-κB activation, thereby suppressing proinflammatory cytokine production (e.g., IL-6, IL-1, TNF-α) in monocytes/macrophages and T cells, contributing to its immunomodulatory effects.
S1960 Pranoprofen Pranoprofen (Pyranoprofen,Pranopulin) is a non-steroidal COX inhibitor, used as an anti-inflammatory drug in ophthalmology.
F0239 PRAS40 Antibody [P22K6]
S1258 Prasugrel Prasugrel (Effient, Efient, Prasita,CS-747, LY640315,PCR 4099) is a thienopyridine ADP receptor (P2Y12) antagonist, used for the reduction of thrombotic cardiovascular events.
S4637 Prasugrel Hydrochloride Prasugrel hydrochloride (Prasugrel HCl, LY640315,PCR 4099 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.
S5713 Pravastatin Pravastatin(CS-514) is a lipoprotein-lowering drug via reversibly inhibiting hydroxymethylglutaryl-CoA (HMG-CoA) reductase and the synthesis of very-low-density lipoproteins.
S3036 Pravastatin (CS-514) Sodium Pravastatin sodium (CS-514) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
S1691 Praziquantel Praziquantel is an anthelmintic effective against flatworms.
S5780 Prazosin Prazosin is an α1-blocker that acts as an inverse agonist at alpha-1 adrenergic receptors. It is used to treat hypertension.
S1424 Prazosin HCl Prazosin HCl (cp-12299-1) is a competitive alpha-1 adrenoceptor antagonist, used to treat high blood pressure or benign prostatic hyperplasia.
F2440 PRC1 Antibody [A3H10]
F3747 PRDM16 Antibody [P2E21]
E5960 PRDX1-IN-1 PRDX1-IN-1 is a celastrol-ligustrazine hybrid and a potent inhibitor of peroxiredoxin 1 (PRDX1) with an IC50 of 0.164 μM. It induces ROS accumulation, inhibits cancer cell growth and metastasis, and exhibits strong antitumor efficacy, making it a promising candidate for lung cancer therapy.
S6950 PRE-084 hydrochloride PRE-084 hydrochloride (HCl) is a potent, selective sigma-1 receptor (σ1, S1R) agonist with IC50 of 44 nM in the sigma receptor assay.
L3900 Preclinical/Clinical Compound Library A unique collection of 3603 preclinical and clinical compounds for high throughput screening (HTS) and high content screening (HCS).
E0530 Prednicarbate Prednicarbate (Dermatop) is a medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions.
S1737 Prednisolone Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
S2570 Prednisolone Acetate Prednisolone Acetate (Omnipred,Prednisolone-21-acetate) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.
S5961 Prednisolone disodium phosphate Prednisolone disodium phosphate (Hydeltrasol, Prednisolone 21-phosphate disodium) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties that exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells.
E6059 prednisolone hemisuccinate Prednisolone hemisuccinate (Prednisolone 21-hemisuccinate) is a synthetic glucocorticoid with anti-inflammatory properties. It is used in the treatment of inner ear diseases and vertigo caused by vestibular hypofunction.
E6078 Prednisolone Tebutate Prednisolone tebutate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester primarily used for its anti-inflammatory and immunosuppressive effects. It significantly suppresses inflammatory responses in models of monosodium urate (MSU) crystal-induced inflammation.
S1622 Prednisone Prednisone is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.
S5489 Prednisone acetate Prednisone acetate (Betapar, Cortan, Deltasone, Fernisone, Meticorten, Prednisone 21-acetate) is a glucocorticoid steroid that can be used as a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties.
S1914 Pregnenolone Pregnenolone(3β-Hydroxy-5-pregnen-20-one) is an endogenous steroid hormone, used in the treatment of fatigue, Alzheimer’s disease, trauma and injuries.
E4945 Pregnenolone monosulfate sodium Pregnenolone monosulfate sodium, a sodium salt form of pregnenolone monosulfate, is an active neurosteroid and a precursor of all steroid hormones. It functions act as a potent endogenous allosteric signal-specific inhibitor of CB1 receptors, reducing psychoactive effects associated with Δ9-tetrahydrocannabinol (THC).
S6910 Preladenant Preladenant (Privadenant, SCH 420814, MK-3814) is a potent, competitive and selective antagonist of the human adenosine A2A receptor with Ki of 1.1 nM.
F0755 Presenilin 1 Antibody [G5E7] Presenilin 1,Presenilin 1/PS-1,Presenilin-1
F3873 Presenilin 1/PS-1 Antibody [G24D17]
F4896 Presenilin 2 Antibody [M18A3]
F1375 Presenilin 2 Antibody [P6E5] Presenilin 2,Presenilin 2/AD5
S1162 Pretomanid (PA-824) PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM.Phase 2.
S6385 Prexasertib (LY2606368)

Prexasertib (LY2606368, ACR 368) is a selective ATP competitor inhibitor of Chk1 and Chk2 with IC50s of 1 nM and 8 nM in cell-free assays, respectively. Prexasertib also inhibits RSK1 with an IC50 of 9 nM in cell-free assay.

S7178 Prexasertib (LY2606368) Dihydrochloride Prexasertib(LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 nmol/L. For CHK2 and RSK, its IC50 values are 8 nM and 9 nM respectively in cell-free assay.
E1538 PRGL493 PRGL493 is a potent and selective inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4). PRGL493 blocks cell proliferation and tumor growth in both breast and prostate cellular and animal models. PRGL493 is used for cancer research.
S8968 PRI-724 (Foscenvivint) Foscenvivint (PRI-724) is a potent and specific inhibitor that disrupts the interaction of β-catenin and CBP.
E1258 Pridopidine Pridopidine (ACR16, ASP2314, FR310826) , a dopamine (DA) stabilizer, acts as an antagonist against sigma 1 receptor (S1R) and dopamine D2 receptor (D2R).
S1619 Prilocaine Prilocaine (NSC 40027) is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation.
S5482 Prilocaine hydrochloride Prilocaine hydrochloride is the hydrochloride salt form of prilocaine, which is a local anesthetic.
S9029 Prim-o-glucosylcimifugin Prim-O-glucosylcimifugin (Cimifugin beta-D-glucopyranoside, Cimifugin 7-glucoside) is a major constituent in Radix Saposhnikovia that has been long used for the treatment of pyrexia, rheumatism, and cancer in traditional Chinese medicine. It shows potential anticancer activity. Prim-O-glucosylcimifugin downregulates the mRNA and protein expression inducible NO synthase (iNOS) and cyclooxygenase 2 (COX-2) in LPS-activated RAW 264.7 macrophages in a concentration-dependent manner.
S7723 PRIMA-1 PRIMA-1 (2,2-Bis(hydroxymethyl)-3-quinuclidinone) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.
E6014 Primaquine Primaquine, an 8-aminoquinoline, is an antimalarial agent and a potent gametocytocidal in falciparum malaria. It also prevents relapse in vivax and ovale malaria.
S4237 Primaquine Diphosphate Primaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria.
S1965 Primidone Primidone (NCI-C56360) is an anticonvulsant of the pyrimidinedione class.
F2115 Prion Antibody [B8A2] Prion Protein,Prion protein PrP,PRNP
E0198 Pristane

Pristane (2,6,10,14-Tetramethylpentadecane, TMPD) is a natural saturated terpenoid alkane obtained primarily from shark liver oil that is widely used to induce tumorgenesis in mice and arthritis and lupus nephritis in rats.

Pristane can be used to induce animal models of Systemic Lupus Erythematosus.
S9404 Pristimerin Pristimerin is a naturally occurring triterpenoid that has been shown to suppress the proliferation of various cancer cell lines at the concentration (IC50) range of 0.2-4 μM, including those of breast, glioma, prostate, pancreatic, ovarian, colon. Pristimerin can inhibits monoacylglycerol lipase(MGL) with an IC50 of 93 nM through a reversible mechanism.
S7546 Pritelivir (BAY 57-1293) Pritelivir (BAY 57-1293, AIC316) is a potent helicase primase inhibitor, exhibiting antiviral effect on herpes simplex virus (HSV) with IC50 of 20 nM for both HSV-1 and HSV-2.
F3987 PRKACG Antibody [H19A15]
F2039 PRKAR2B Antibody [L21D1]
E0140 PRL-3 Inhibitor (Compound 5e)

PRL-3 Inhibitor (Compound 5e) is a potent PRL-3 inhibitor with an IC50 of 0.9 μM.

F2422 PRMT1 Antibody [B18H13] PRMT1
F4736 PRMT4/CARM1 Antibody [J8A9]
F1009 PRMT5 Antibody [N4N24] Protein arginine N-methyltransferase 5, PRMT5, 72 kDa ICln-binding protein, Histone-arginine N-methyltransferase PRMT5, Jak-binding protein 1 Shk1 kinase-binding protein 1 homolog, SKB1 homolog, SKB1Hs, PRMT5, HRMT1L5, IBP72, JBP1, SKB1
F1966 PRMT6 Antibody [H12B3]
F1295 PRMT7 Antibody [H13L7]
S9944 PRN1008 PRN1008 (Rilzabrutinib) is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK), with an IC50 of 1.3 nM.
S8578 PRN1371 PRN1371 is an irreversible covalent FGFR1-4 kinase inhibitor, with IC50s of 0.6, 1.3, 4.1, 19.3 and 8.1 nM for FGFR1, 2, 3, 4 and CSF1R, respectively.
F1715 pro Caspase3 Antibody [H9J6]
F1623 pro NGF Antibody [J14K17]
S5105 Proanthocyanidins Proanthocyanidins (PAs), also known as condensed tannins, are a class of polyphenols found in a variety of plants. They are very powerful antioxidants that remove harmful free oxygen radicals from cells.
S4022 Probenecid Probenecid (Benemid) is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16. Probenecid is also a clinically used broad-spectrum Pannexin1 (Panx1) blocker.
S2119 Probucol Probucol (DH-581) is an anti-hyperlipidemic drug by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
S4294 Procainamide HCl Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias.
S4023 Procaine HCl Procaine (Novocaine) is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM, which is also an inhibitor of 5-HT3 with KD of 1.7 μM.
S4979 Procaine penicillin G Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic.
S1995 Procarbazine HCl Procarbazine HCl (NSC-77213) is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound, used for the treatment of Hodgkin's lymphoma.
S2083 Procaterol HCl Procaterol HCl (OPC-2009) is a short-acting β2-adrenergic receptor agonist with Kp of 8 nM, used for the treatment of asthma
S4631 Prochlorperazine dimaleate salt Prochlorperazine dimaleate salt is a dopamine (D2) receptor antagonist.
S4408 Procodazole Procodazole (Propazol, 2-Benzimidazolepropionic acid, 3-(1H-benzimidazole-2) propanoic acid) is used as a potentiator which is non-specific active immunoprotective against viral and bacterial infections.
E0240 Procyanidin B1

Procyanidin B1, a natural polyphenolic compound that has antioxidant properties, inhibits Kv10.1 channel and suppresses the evolution of hepatoma.

S3290 Procyanidin B2 (PCB2) Procyanidin B2 (PCB2), a natural flavonoid found in commonly consumed foods, possess anti-inflammatory, anti-oxidant and anti-cancer activities. Procyanidin B2 activates PPARγ to induce M2 polarization in mouse macrophages. Procyanidin B2 significantly suppresses the activation of NLRP3 inflammasome in the lung tissue induced by paraquat in the rat model.
E0478 Procyanidin C1 Procyanidin C1 is a polyphenolic component of grape seed extract, increases the healthspan and lifespan of mice through its action on senescent cells. PCC1 is a natural senotherapeutic agent with in vivo activity and a potential intervention to delay, alleviate or prevent age-related pathologies.
S8233 Prodigiosin Prodigiosin is a natural red pigment produced by numerous bacterial species which can inhibit Wnt/β-catenin pathway.
F2974 Profilin 1 Antibody [M2C23] Profilin 1,Profilin-1
S5776 Proflavine Proflavine (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria. It is a topical antiseptic used mainly in wound dressings.
S4236 Proflavine Hemisulfate Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands.
F2441 Progerin Antibody [J17D10]
S1705 Progesterone Progesterone is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor.
F0452 Progesterone Receptor A/B Antibody [E5B3] Progesterone Receptor A/B
F0809 Progesterone Receptor B Antibody [B13J21]
S5927 Proguanil Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
S3082 Proguanil HCl(Atovaquone) Proguanil hydrochloride(Chloroguanil, Chlorguanide hydrochloride), an antimalarial proagent acts as an inhibitor of dihydrofolate reductase (DHFR). Proguanil acts as a biguanide to enhance the Atovaquone effect.
F2433 Prohibitin Antibody [A14G6] PHB1,Prohibitin
S5622 Prohydrojasmon Prohydrojasmon is a newly launched plant growth regulator, which has jasmonic acid activity.
S5428 Promazine hydrochloride Promazine (Romtiazin, Sinophenin) is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors with antipsychotic effects.
S3657 Promestriene Promestriene (3-propyl ethyl, 17B-methyl estradiol) is a synthetic estrogen analog that has been reported to significantly improve the symptoms of vaginal atrophy caused by estrogen deprivation in topical application.
S5196 Promethazine Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties.
S4293 Promethazine HCl Promethazine HCl is a potent histamine H1 receptor antagonist, used as a sedative and antiallergic medication.
S4867 Propacetamol hydrochloride Propacetamol hydrochloride (PRO) is a water-soluble prodrug of paracetamol (PA) which can be parenterally administered as analgesic for the treatment of postoperative pain, acute trauma, and gastric and/or intestinal disorders.
S5789 Propafenone Propafenone (SA-79) is an orally active sodium channel blocking agent and a beta-adrenoceptor (β-adrenergic receptor) antagonist. Propafenone offers a broad spectrum of activity in the treatment of cardiac arrhythmias.Propafenone can be used to induce animal models of Heart Failure.
S2500 Propafenone HCl Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.Propafenone HCl can be used to induce animal models of Heart Failure.
S4834 Propantheline bromide Propantheline bromide (Pro-Banthine, Neometantyl, Neopepulsan) is a muscarinic antagonist used to treat gastrointestinal conditions associated with intestinal spasm and to decrease secretions during anesthesia.
S1828 Proparacaine HCl Proparacaine HCl(Proxymetacaine Hydrochloride) is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.
S0655 Propargyl-PEG4-NHS ester Propargyl-PEG4-NHS ester is a 4-unit amine reactive PEG linker for antibody-drug-conjugation (ADC) which is noncleavable.
S6874 Propidium Iodide Propidium iodide (PI) is a red-fluorescent DNA stain which penetrates only damaged cellular membranes. Propidium iodide (PI) is described for use in the determination of cell viability in cell suspension.
E2869 Propiolactone Propiolactone(β-Propiolactone), a sterilizing and sporicidal agent, is used to sterilize blood plasma, vaccines, tissue grafts, surgical instruments and enzymes.
E4808 Propionyl-L-carnitine hydrochloride Propionyl-L-carnitine hydrochloride(Levocarnitine propionate hydrochloride) supports mitochondrial metabolism, offers cardiovascular benefits, acts as a free radical scavenger, and is used in treating colonic inflammatory bowel disease.
S4931 Propiverine hydrochloride Propiverine is an anticholinergic drug used for the treatment of overactive bladder and urinary incontinence. Propiverine is a muscarinic receptor antagonist possessing additional properties, i.e., block of L-type Ca2+ channels.
E5827 Propranolol Propranolol is a non-selective antagonist of β-adrenergic receptors (βAR), with Ki values of 1.8 nM for β1AR and 0.8 nM for β2AR, effectively lowering cAMP levels and activating the MAPK pathway downstream of βARs. It is an effective treatment for infantile hemangiomas (IHs), where it induces antiproliferative and antisurvival effects on hemangioma stem cells (HemSCs).
S4076 Propranolol HCl Propranolol HCl (AY-64043, ICI-45520, NCS-91523) is a competitive non-selective beta-adrenergic receptors inhibitor.
S5113 Propyl gallate Propyl gallate (Gallic acid propyl esterZ, n-Propyl gallate) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.
E0940 Propyl pyrazole triol (PPT) Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist.
S5405 Propylparaben Propylparaben (Propyl 4-hydroxybenzoate, Propyl p-hydroxybenzoate, nipasol), a natural substance found in many plants and some insects, is an antimicrobial, preservative and flavouring agent.
S1988 Propylthiouracil Propylthiouracil (NSC 6498, NSC 70461) is a thyroperoxidase and 5'-deiodinase inhibitor, used to treat hyperthyroidism.
S5309 Propyphenazone (4-Isopropylantipyrine) Propyphenazone(4-Isopropylantipyrine, Isopropyrine), an analgesic and antipyretic agent, is a selective cyclooxygenase-2 inhibitor with anti-inflammatory activity.
F2844 Prostaglandin D Synthase (Lipocalin)/PDS Antibody [A1L2]
F2783 Prostaglandin E Receptor EP2/PTGER2 Antibody [L20C8]
S3003 Prostaglandin E2 (PGE2) Prostaglandin E2 (PGE2, Dinoprostone) plays important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts. It is easy to discolor when stored in liquid environment for a long time. It is recommended to store it in powder form and try to use it as soon as possible!
F2479 Prosurfactant Protein C Antibody [N9F13] Prosurfactant Protein C,Prosurfactant Protein C (proSP-C),surfactant protein c/SP-C
S9672 PROTAC SGK3 degrader-1 PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC conjugate of the 308-R SGK inhibitor with the VH032 VHL binding ligand, targeting SGK3 (Serum/Glucocorticoid Regulated Kinase Family Member 3) for degradation.
P1169 Protamine sulfate Protamine sulfate is a polycationic, highly positively charged protein derived from salmon sperm protein, used to neutralize unfractionated heparin administration (UFH)-induced anticoagulation following cardiovascular surgical procedures.
L2500 Protease Inhibitor Library A unique collection of 454 small molecule inhibitors used for chemical genomics, high-throughput screening (HTS), and high content screening (HCS).
F3699 Proteasome 20S LMP7 Antibody [N6D20] Proteasome 20S LMP7,PSMB8/LMP7
F2405 Protein CASP Antibody [J23N1]
L8100 Protein-protein Interaction Inhibitor Library A unique collection of 407 protein-protein Interaction(PPI) Inhibitors used for high throughput screening(HTS) and high content screening(HCS).
P1242 Proteinase K Proteinase K is a serine endoprotease, is used for isolating amyloid cores and is effective over a wide pH range (4–12), including in the presence of SDS or urea. It is commonly used as a preparative reagent for destruction of proteins, including DNAses and RNAses, in DNA and RNA preparations.
S1881 Protionamide Protionamide (Prothionamide, 1321-TH) is a drug used in the treatment of tuberculosis.
S3975 Protocatechuic acid Protocatechuic acid (PCA, 3,4-Dihydroxybenzoic acid, Protocatechuate), a dihydroxybenzoic acid, is a type of widely distributed naturally occurring phenolic acid.
E1746 Protokylol hydrochloride Protokylol hydrochloride(Caytine hydrochloride, JB-251 hydrochloride) is a salt form of protokylol and is an agonist of β-adrenergic receptor. Protokylol hydrochloride is also used as a bronchodilator.
S3883 Protopine Protopine (Corydinine, Fumarine, Biflorine, Macleyine), an alkaloid present in different plants, has been shown to exhibit a number of activities, such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation. It also possesses anti-cholinergic and anti-histaminic as well as anti-bacterial activities.
S5145 Protoporphyrin IX (PPIX) Protoporphyrin IX (PPIX) is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.
S7880 Protoporphyrin IX Zinc Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an potent, orally active and competitive heme oxygenase-1 (HO-1) inhibitor and significantly reduces the protective effects of Phloroglucinol (PG) against hydrogen peroxide.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
S9243 Protosappanin B Protosappanin B (FT-0689654, Q-100961), extracted from Lignum Sappan, possesses anti-inflammation and anti-oxidation properties.
S9510 Protriptyline hydrochloride Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline. Protriptyline is a tricyclic secondary amine with antidepressant property which acts by inhibition of serotonin and norepinephrine reuptake.
F2796 PROX1 Antibody [E13N19] Prox 1,PROX1
S9898 Proxalutamide (GT0918)

Proxalutamide (GT0918) is a second-generation androgen receptor antagonist that binds to the ligand-binding domain of AR with an IC50 of 32 nM in the AR competive binding assays.

S4932 Proxyphylline Proxyphylline (Monophylline, Spasmolysin) is a derivative of theophylline which is used as a bronchodilator and for its cardiovascular properties. It selectively antagonizes A1 adenosine receptors (Ki = 82 nM for bovine brain) versus A2 adenosine receptors (Ki = 850 µM for platelets).
S7738 PRT-060318 2HCl PRT-060318 (PRT318) is a novel selective inhibitor of the Syk tyrosine kinase with an IC50 of 4 nM, as an approach to HIT treatment.
E7793 PRT062607 PRT062607 is a highly specific, potent and orally bioavailable inhibitor of purified Spleen tyrosine kinase (SYK) with an IC50 of 1-2 nM. It exhibits significant anti-inflammatory activity and can be used in non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL) and rheumatoid arthritis research.
S8032 PRT062607 (P505-15) HCl PRT062607 (P505-15, BIIB057, PRT-2607) HCl is a novel, highly selective Syk inhibitor with IC50 of 1 nM in cell-free assays, >80-fold selective for Syk than Fgr, PAK5, Lyn, FAK, Pyk2, FLT3, MLK1 and Zap70.
S5315 PRT4165 PRT4165 is a Bmi1/Ring1A inhibitor with an IC50 of 3.9 µM in the cell-free assay and also inhibits PRC1-mediated H2A ubiquitylation in vivo and in vitro.
E1658 PRT543 PRT543 is a potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) with broad antitumor activity in vitro and in vivo. It also inhibits the methyltransferase activity of the PRMT5/MEP50 complex with an IC50 of 10.8 nM.
S2875 Prucalopride Prucalopride (R-93877) is a selective, high affinity 5-HT receptor agonist for 5-HT4A and 5-HT4B receptor with Ki of 2.5 nM and 8 nM, respectively, exhibits >290-fold selectivity against other 5-HT receptor subtypes.
S4247 Prucalopride Succinate Prucalopride(R-108512) is a selective, high affinity 5-HT4 receptor agonist. The Ki values of prucalopride for human 5-HT(4a) and 5-HT(4b) receptor are 2.5 nM and 8 nM, respectively.
S2071 Prulifloxacin (NM441) Prulifloxacin (NM441, AF 3013), the prodrug of ulifloxacin, is a broad-spectrum oral fluoroquinolone antibacterial agent.
S8010 PRX-08066 Maleic acid PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2.
S7691 PS-1145 PS-1145 is a specific IKK inhibitor with IC50 of 88 nM.
S7586 PS-48 PS-48 is an allosteric activator of phosphoinositide-dependent protein kinase-1 (PDK1).
S3462 PS210 PS210 is a potent activator of PDK1 that binds to the PIF-pocket and allosterically modulates the active site of PDK1.
E2816 PS47 PS47 is an inactive E isomer of PS48, an activator of 3-Phosphoinositide-dependent protein kinase 1 (PDPK1).
F4660 PSA/KLK3 Antibody [M14P16]
F3124 PSD-95 Antibody [H11A14] Post Synaptic Density Protein 95,PSD95,PSD-95
F0240 PSD95 Antibody [F17C8] Post Synaptic Density Protein 95,PSD95,PSD-95
E0831 Pseudocoptisine chloride Pseudocoptisine chloride (Isocoptisine chloride) is a quaternary alkaloid with benzylisoquinoline skeleton isolated from Corydalis Tuber, inhibits acetylcholinesterase (AChE) activity with an IC50 of 12.8 μM, showing anti-inflammatory and anti-amnestic effects.
S9199 Pseudoginsenoside F11 Pseudoginsenoside F11, a natural product found in American ginseng but not in Asian ginseng, is a novel partial PPARγ agonist.
E0249 Pseudolaric Acid A Pseudolaric acid A, a Hsp90 inhibitor with an IC50 of 0.60 μM, 2.72 μM, 1.36 μM, 2.92 μM and 6.16 μM in HL-60, A549, SMMC-7721, HeLa and SW480 cells respectively, is the main bioactive ingredient in Pseudolarix cortex, and induces cell cycle arrest at G2/M phase and promotes cell death through caspase-8/caspase-3 pathway, demonstrating potent antiproliferation and anticancer activities.
S5373 Pseudolaric Acid B Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.
S9067 Pseudoprotodioscin Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
E4356 Pseudotropine Pseudotropine(3β-Tropanol, ψ-Tropine) is an alkaloid and a plant metabolite of the tropane tropinone that has been found in A. belladonna. It is used in the preparation of novel nicotinic receptor agonists.
F3447 PSF1 Antibody [E5F3]
S5307 PSI-6206 (GS-331007) PSI-6206 (RO-2433, GS-331007) is a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase, targeting NS5B polymerase.
F4988 PSMA Antibody [A11C13]
F1010 PSMA Antibody [N17H9] Prostate Specific Membrane Antigen,PSMA,PSMA (FOLH1)
F2843 PSMB10/MECL1 Antibody [D18D5]
F1421 PSMB5 Antibody [F16L3] PSMB5,PSMB5/MB1
F1514 PSMB6 Antibody [P14M13]
F1296 PSMD11 Antibody [L2N1]
F1105 PSMD14 Antibody [D2B20] PSMD14 Rabbit mAb recognizes endogenous levels of total PSMD14 protein.
F4741 PSMD14 Antibody [G24K15]
F6850 PSMD2 Antibody [B5P6]
S4737 Psoralen Psoralen (Psoralene, Ficusin, Furocoumarin) is a naturally occurring furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
F2123 Psoriasin Antibody [L12L3] Psoriasin,S100A7,S100A7/Psoriasin
F4483 PSR Antibody [F14P18]
E5952 PT 3 PT 3 is a benzamide-class, potent, and selective inhibitor of Histone Deacetylase 3 (HDAC3) with an IC50 of 245 nM. It crosses the blood-brain barrier and enhances learning and memory in novel object recognition models in mice.
E1937 PT-179 PT-179, an orthogonal Thalidomide derivative targets cereblon without causing off-target degradation effects. PT-179 specifically binds CRBN, forms a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediates the degradation of the tagged protein.
S8352 PT2385 PT2385 is a HIF-2α antagonist with luciferase EC50 of 27 nM and no significant off-target activity.
S8351 PT2399 PT2399 is a potent and orally available antagonist of HIF-2 that selectively disrupts the heterodimerization of HIF-2α with HIF-1β.
S8886 PT2977 (Belzutifan) Belzutifan (PT2977), an orally active and selective HIF-2α inhibitor, increases potency and improves pharmacokinetic profile, providing a potential treatment for clear cell renal cell carcinoma (ccRCC).
F2575 PTBP1 Antibody [P20K3]
S7372 PTC-209 PTC-209 is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM in HEK293T cell line, and results in irreversible reduction of cancer-initiating cells (CICs).
F2641 PTCH1 Antibody [K3H23] Patched / PTCH1,PTCH1
F3548 PTEN Antibody [J22G2]
S3937 Pterostilbene Pterostilbene is a natural dietary compound and the primary antioxidant component of blueberries. It has been implicated in anticarcinogenesis, modulation of neurological disease, anti-inflammation, attenuation of vascular disease, and amelioration of diabetes.
S0924 Pteryxin Pteryxin ((+)-Pteryxin), a dihydropyranocoumarin derivative found in Apiaceae family, is a potent inhibitor of butyrylcholinesterase (BChE) with IC50 of 12.96 μg/ml. Pteryxin inhibits LPS-induced nitric oxide production in mouse peritoneal macrophages with IC50 of 20 µM. Pteryxin is potential for Alzheimer's disease (AD) treatment.
E0791 PTGR2-IN-1 PTGR2-IN-1 is a potent prostaglandin reductase 2 (PTGR2) inhibitor with an IC50 of ~0.7 μM.
F3430 PTN Antibody [B1M21]
S3696 PTP Inhibitor I PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor with Ki values of 43 and 42 μM for SHP-1(ΔSH2) and PTP1B, respectively.
S3678 PTP Inhibitor II PTP Inhibitor II (NSC 129010, 4-(Bromoacetyl)anisole) is a cell-permeable protein tyrosine phosphatase (PTP) inhibitor that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with Ki value of 128 μM.
F0954 PTP-PEST Antibody [A18N23]
F3193 PTP1B Antibody [B2E10]
S0119 PTP1B-IN-2 PTP1B-IN-2 (MDK3465, Ptp1B-In-2, Compound P6) is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM. PTP1B-IN-2 enhances insulin-mediated insulin receptor β (IRβ) phosphorylation and insulin-stimulated glucose uptake.
F0442 PU.1 Antibody [B4N6] PU.1,PU.1/Spi1
E5829 PU139 PU139 is a potent inhibitor of pan-histone acetyltransferase (HAT) that blocks Gcn5, PCAF, CBP, and p300 with IC50 values of 8.39 μM, 9.74 μM, 2.49 μM, and 5.35 μM, respectively. It significantly impairs Smp14 promoter activity, suggesting that targeting SmGCN5 and SmCBP1 is a novel strategy to control S. mansoni egg development, it also exhibits anticancer activity.
S2346 Puerarin Puerarin (Kakonein), an isoflavones found in the root of Radix puerariae, is a 5-HT2C receptor and benzodiazepine site antagonist.
S9271 Pulchinenoside A Pulchinenoside A (Anemoside A3), a natural triterpenoid saponin, is a AMPARs and NMDAR modulator.
S9140 Pulegone Pulegone, a naturally occurring organic compound, is a fragrance and flavour ingredient.pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations.
S0356 Pulrodemstat (CC-90011) besylate Pulrodemstat (CC-90011) besylate (LSD1-IN-7 benzenesulfonate) is a potent and orally active lysine specific demethylase-1 (LSD1) inhibitor that is found to be effective in various tumors.
S9308 Pulsatilla saponin D Pulsatilla saponin D (SB365), isolated from the root of Pulsatilla koreana, targets c-Met and exerts antiangiogenic and antitumor activities.
F0558 Puma Antibody [L23F7] Puma,PUMAα/β
F4191 Puma Antibody [L5K18]
F2990 Pumilio 1 Antibody [N12C17]
S9131 Punicalagin Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects., Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects.
S6359 Purine Purine is a heterocyclic aromatic organic compound which plays crucial roles in DNA and RNA. It is also significant components in a number of other important biomolecules, such as ATP, GTP, cyclic AMP, NADH, and coenzyme A.
S3042 Purmorphamine Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM. Purmorphamine can reduce both basal and induced autophagy.
E4996 Puromycin Puromycin (CL13900, Puromycine) is an antibiotic, analog of the 3' end of aminoacyl-tRNA and an inhibitor of protein synthesis that mimics tyrosyl-tRNA, causing premature termination of translation. It blocks translation by labeling and releasing elongating polypeptide chains from ribosomes and has been widely used in molecular biology research.
S9631 Puromycin aminonucleoside Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN), the aminonucleoside portion of the antibiotic puromycin, is a reversible inhibitor of dipeptidyl-peptidase II and cytosol alanyl aminopeptidase that induces apoptosis in mesangial cells (MCs) accompanied by declined cell viability and enhanced inflammatory response.Puromycin aminonucleoside can be used to induce animal models of Kidney Disease.
S7417 Puromycin Dihydrochloride Puromycin 2HCl is an aminonucleoside antibiotic derived from Streptomyces alboniger. It is an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinated expression of genes during cell differentiation.
S4963 Purpurin Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin) is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. It exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. Purpurin strongly inhibits the activities of CYP1A1, CYP1A2 and CYP1B1.
E7081 Purpurin 18 Purpurin-18 is a chlorophyll-derived dihydroporphyrin, serves as a key precursor for photosensitizers like purpurinimides, which absorb light in the 700–850 nm range. It demonstrate potent photodynamic anti-tumor activity and generates ROS, disrupting mitochondrial membrane potential and inducing apoptosis against triple-negative breast cancer both in vitro and in vivo.
S7793 Purvalanol A Purvalanol A is a potent, and cell-permeable CDK inhibitor with IC50 of 4 nM, 70 nM, 35 nM, and 850 nM for cdc2-cyclin B, cdk2-cyclin A, cdk2-cyclin E, and cdk4-cyclin D1, respectively. Purvalanol A induces endoplasmic reticulum stress-mediated apoptosis and autophagy.
S0500 Purvalanol B Purvalanol B (NG-95) is a potent and selective inhibitor of cyclin-dependent kinase (CDK) with IC50 of 6 nM, 6 nM, 9 nM and 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively.
S3596 PVP (Polyvinylpyrrolidone) PVP (Polyvinylpyrrolidone) is an inert, water-soluble, non-toxic, temperature-resistant, pH-stable, biocompatible, biodegradable polymer that helps to encapsulate and cater both hydrophilic and lipophilic drugs. Polyvinylpyrrolidone has been widely tested and used as an effective wound healing accelerator.
F4102 PVR/CD155 Antibody [D7N14]
S7947 PX-12 PX-12 (DB05448, 1-methyl propyl 2-imidazolyl disulfide) is a potent thioredoxin-1 (Trx-1) inhibitor by irreversibly thioalkylation of Cys73 of Trx-1. Phase 2.
S7612 PX-478 Dihydrochloride PX-478 2HCl is an orally active, and selective hypoxia-inducible factor-1α (HIF-1α) inhibitor. PX-478 2HCl induces apoptosis and has anti-tumor activity. Phase 1.
S9861 PY-60 PY-60 is a small-molecule activator of the transcriptional coactivator Yes-associated protein (YAP) with EC50 of 1.6 µM, which acts by inhibiting a central scaffolding protein in the Hippo pathway, Annexin A2. It promotes the regenerative repair of cutaneous wounds in pig and human models.
F4657 Pyk2 Antibody [L19B9]
F1208 PYK2 Antibody [L4N9] Pyk2
E4633 Pyocyanin Pyocyanin(Pyocyanine; Sanazin; Sanasin) is a redox-active toxin produced by Pseudomonas aeruginosa that generates oxidative stress and selectively harms quorum sensing (QS)-defective mutant bacteria. It acts as a social policing agent, promoting the survival of QS-proficient and more virulent bacterial populations.
S7129 PYR-41 PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2. PYR-41 induce apoptosis.
E4659 Pyr3 Pyr3 is a selective and potent inhibitor of transient receptor potential canonical channel 3 (TRPC3). It inhibits TRPC3-mediated Ca2+ influx in a dose-dependent manner with the IC50 value of 0.7 μM. It holds potential for treating TRPC3-related diseases like cardiac hypertrophy.
S2501 Pyrantel Pamoate Pyrantel pamoate (Pyrantel Embonate), a broad-spectrum anthelmintic drug, is used to treat a number of parasitic worm infections.
S1762 Pyrazinamide Pyrazinamide (Pyrazinoic Acid Amide) is an agent used to treat tuberculosis.
S3093 Pyrazole

Pyrazole (1H-pyrazole) is a five membered heteroaromatic ring with two nitrogen atoms is of immense significance. Pyrazole is an indispensable anchor for design and development of new pharmacological agents.

S6789 Pyridone 6 Pyridone 6 is a pan-JAK inhibitor with IC50s of 1 nM, 1 nM, 5 nM and 15 nM for JAK2, TYK2, JAK3 and JAK1, respectively.
E8172 Pyridostatin Pyridostatin (RR82) is a highly selective small molecule that stabilizes telomeric DNA G-quadruplex with a Kd of 490 nM, promoting their folding and inducing dysfunctional telomeres by uncapping POT1 and activating DNA damage signaling. It also modulates gene expression, reducing SRC protein levels and SRC-dependent motility in breast cancer cells, contributing to its anti-proliferative effects.
S7444 Pyridostatin Trifluoroacetate Salt Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes.
S4871 Pyridoxal 5-phosphate monohydrate Pyridoxal 5-phosphate monohydrate is an active vitamin B6 metabolite, which is a cofactor in many reactions of amino acid metabolism.
S6115 Pyridoxal 5′-phosphate hydrate Pyridoxal 5′-phosphate (pyridoxal phosphate, Vitamin B6 phosphate, PAL-P, PLP), a vitamin B6 phosphate, is a coenzyme in a variety of enzymatic reactions. Pyridoxal 5′-phosphate at concentrations < 0.5 mM inhibits of polymerization deoxynucleoside triphosphate catalysed by variety of DNA polymerases isolated from type C RNA tumor viruses. The combination of Pyridoxal 5′-phosphate and NEIL2 will make NEIL2 completely lose its ability to bind damaged DNA.
S3111 Pyridoxal hydrochloride

Pyridoxal hydrochloride (HQ) is an active endogenous metabolite.

S5311 Pyridoxal phosphate Pyridoxal phosphate (Pyridoxal 5'-phosphate, PAL-P, PLP, Vitamin B6), the active form of vitamin B6, acts as a coenzyme in all transamination reactions, and in certain decarboxylation, deamination, and racemization reactions of amino acids.
S3980 Pyridoxine Pyridoxine (Pyridoxol, Vitamin B6, Gravidox), also known as vitamin B6, is a form of vitamin B6 found commonly in food and used as dietary supplement. It is a cofactor for both glutamic acid decarboxylase and GABA transaminase.
S3113 Pyridoxine HCl Pyridoxine HCl (Vitamin B6,Pyridoxol hydrochloride) is a form of vitamin B6.
S4382 Pyrilamine Maleate Pyrilamine Maleate (Mepyramine)is a histamine H1 receptor inverse agonist, it binds to a G protein-coupled form of the receptor and promotes a G protein-coupled inactive state of the H1 receptor that interferes with the Gq/11-mediated signaling.
E0608 Pyrilutamide (KX-826) Pyrilutamide (KX-826) is an antagonist of androgen receptor (AR) and a potential first-in-class topical drug for the treatment of androgenetic alopecia (AGA) and acne vulgaris.
S2006 Pyrimethamine Pyrimethamine(RP 4753) is a dihydrofolate reductase (DHFR) inhibitor, used as an antimalarial drug.
E4265 Pyrimidine Pyrimidine is an endogenous metabolite. It is used to study the photoinduced ion chemistry of the halogenated pyrimidines, a class of prototype radiosensitizing molecules, and is also used to assess pyrimidine/purine asymmetry quantitatively.
E0462 Pyrintegrin Pyrintegrin is an β1-integrin agonist and a 2,4-disubstituted pyrimidine that promotes embryonic stem cells survival, also enhances cell-extracellular matrix (ECM) adhesion-mediated integrin signaling.
S5798 Pyriproxyfen Pyriproxyfen (S-31183) is an insect growth regulator that has been widely used worldwide as a larvicide in vector control and in agriculture to fight a very large number of pests.
S5141 Pyrithioxin Pyrithioxin (Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide) is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.
S4730 Pyrithioxin Dihydrochloride Pyrithioxin (Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide) Dihydrochloride is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate with no vitamin B6 activity.
S3885 Pyrogallol Pyrogallol (1,2,3-trihydroxybenzene), an organic compound belonging to the phenol family, used as a photographic film developer and in the preparation of other chemicals. It is known to be a superoxide anion generator and ROS inducer.
E7970 Pyronaridine Pyronaridine is a lipophilic Mannich base with potent antimalarial and potential antiviral activities. It inhibits haemozoin formation in Plasmodium by binding haematin, leading to parasite death. Pyronaridine is also active against P. falciparum and has shown efficacy against Echinococcus granulosus infections.
E4451 Pyronin Y Pyronin Y is a fluorescent probe which stains double stranded RNA in living or fixed cells as well as in tissues.
L7400 Pyroptosis Compound Library A unique collection of 751 pyroptosis related compounds used for high throughput screening(HTS) and high content screening(HCS).
S8852 Pyrotinib dimaleate Pyrotinib dimaleate is a potent and selective irreversible dual tyrosine kinase inhibitor of EGFR and HER2 with IC50 of 0.013 μM and 0.038 μM, respectively.
S2190 Pyroxamide (NSC 696085) Pyroxamide(NSC 696085) is a potent inhibitor of affinity-purified HDAC1 with ID50 of 100 nM. It also induces growth suppression and cell death in human rhabdomyosarcoma in vitro.
S5832 Pyrrole-2-carboxylic acid Pyrrole-2-carboxylic acid (2-Pyrrolecarboxylic acid) is a degradation product of sialic acids and a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase.
S3578 Pyrroloquinoline quinone Pyrroloquinoline quinone (PQQ, Methoxatin) is a natural anti-oxidant with anti-oxidative and anti-aging effects. Pyrroloquinoline quinone prevents estrogen deficiency-induced osteoporosis.Pyrroloquinoline quinone can alleviate allergic airway inflammation in mice by improving the immune microenvironment and regulating the JAK-STAT signaling pathway. This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
S5263 Pyrroloquinoline Quinone Disodium Salt Pyrroloquinoline quinone (methoxatin disodium salt), an aromatic tricyclic o-quinone, is a redox cofactor for bacterial dehydrogenases. It is an efficient electron transfer catalyst from a number of organic substrates to molecular oxygen (O2), constructing quinoprotein model reactions.
F1657 Pyruvate dehydrogenase E2/E3bp Antibody [P23D24]
S3143 Pyruvic acid

Pyruvic acid (Acetylformic acid) is an important organic chemical intermediate that plays a role in cardiomyocyte pathophysiology and therapy. Pyruvic acid markedly increases the level of lactate dehydrogenase (LDH) and creatine kinase (CK) and reduces the level of Ca2+Mg2+-ATPase and Na+K+-ATPase.

S5816 Pyrvinium pamoate Pyrvinium pamoate(Pyrvinium embonate) is an anthelmintic effective for pinworms.
E7952 PYZD-4409 PYZD-4409 is a potent and specific small molecule inhibitor of the ubiquitin-activating enzyme UBA1 (E1) with an IC50 of 20 μM. It induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells and can be used as a research for developing treatments for hematologic malignancies.
S0798 PZ-2891 PZ-2891 is a selective, orally active and brain-penetrant pantothenate kinase (PANK) modulator that acts as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits PANK with IC50 of 40.2 nM, 0.7 nM and 1.3 nM for hPANK1β, hPANK2, and hPANK3, respectively.
E5989 PZL-A PZL-A is a activator of mitochondrial DNA (mtDNA) synthesis. PZL-A restores wild-type-like activity to mutant forms of polymerase γ (POLγ) with 160 nM for A467T and 20 nM for G848S. In cellular systems, PZL-A stimulates mtDNA synthesis, promoting oxidative phosphorylation complex biogenesis and improving cellular respiration. PZL-A is promising agent for relieving POLG disease and other severe conditions linked to depletion of mtDNA.
E7448 [Pyr1]-Apelin-13 [Pyr1]-Apelin-13 is one of the endogenous agonists of the APJ receptor with high binding affinity Kd of 4.5 nM for hAPJ, predominantly found in the myocardium and plasma. It exhibits analgesic effects and improves cardiovascular function, making it a promising candidate for neuropathic pain and heart failure research.
E2898 ε-poly-L-lysine HCl ε-poly-L-lysine (ε-PL) is a naturally occurring poly(amino acid), which possesses excellent antimicrobial activity and has been widely used in food and pharmaceutical industries.This product is very susceptible to moisture, please keep it sealed!